Page last updated: 2024-08-07 12:45:32
5-hydroxytryptamine receptor 3A
[no definition available]
Synonyms
5-HT3-A;
5-HT3A;
5-hydroxytryptamine receptor 3;
5-HT-3;
5-HT3R;
Serotonin receptor 3A;
Serotonin-gated ion channel receptor
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
Compounds (12)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| granisetron | Cavia porcellus (domestic guinea pig) | Ki | 0.0040 | 1 | 1 |
| quipazine | Cavia porcellus (domestic guinea pig) | Ki | 6.6670 | 2 | 3 |
| aripiprazole | Cavia porcellus (domestic guinea pig) | IC50 | 630.0000 | 1 | 1 |
| 3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole | Cavia porcellus (domestic guinea pig) | IC50 | 0.6900 | 1 | 1 |
| trichostatin a | Cavia porcellus (domestic guinea pig) | IC50 | 7.6900 | 1 | 1 |
| 2-(1-(2-allylphenoxy)ethyl)-4,5-dihydro-1h-imidazole | Cavia porcellus (domestic guinea pig) | Ki | 0.0851 | 1 | 1 |
| clozapine | Cavia porcellus (domestic guinea pig) | IC50 | 110.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| clonidine | Cavia porcellus (domestic guinea pig) | EC50 | 0.0083 | 1 | 1 |
| ondansetron | Cavia porcellus (domestic guinea pig) | Kd | 0.0776 | 1 | 1 |
| benziodarone | Cavia porcellus (domestic guinea pig) | Kd | 8.0000 | 1 | 1 |
| 3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone | Cavia porcellus (domestic guinea pig) | Kd | 5.0000 | 1 | 1 |
| 3-methoxy-n-p-tolylquinoxalin-2-carboxamide | Cavia porcellus (domestic guinea pig) | Kd | 0.0501 | 1 | 1 |