A neuraminidase subtype N2 (Influenza A virus) that is encoded in the genome of the H2N2 strain A/Singapore/1/1957. [PMID:14741372, PMID:15380362, PMID:15567494, PMID:15744059, PMID:16192481, PRO:CNA, PRO:DNx, UniProtKB:Q6XUE4]
EC 3.2.1.18
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| zanamivir | Influenza A virus (A/Singapore/1/1957(H2N2)) | IC50 | 0.0070 | 2 | 4 |
| oseltamivir | Influenza A virus (A/Singapore/1/1957(H2N2)) | IC50 | 0.0030 | 1 | 2 |
| bcx 1812 | Influenza A virus (A/Singapore/1/1957(H2N2)) | IC50 | 0.0030 | 1 | 2 |
| bana 113 | Influenza A virus (A/Singapore/1/1957(H2N2)) | IC50 | 10.0000 | 1 | 1 |
| bana-108 | Influenza A virus (A/Singapore/1/1957(H2N2)) | IC50 | 10,000.0000 | 1 | 1 |