Page last updated: 2024-11-12
2,7-diamino-1,8-naphthyridine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
2,7-diamino-1,8-naphthyridine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11240647 |
| CHEMBL ID | 4513776 |
| SCHEMBL ID | 1765925 |
| MeSH ID | M0528302 |
Synonyms (8)
| Synonym |
|---|
| 1,8-naphthyridine-2,7-diamine |
| [1,8]naphthyridine-2,7-diamine |
| AKOS006291347 |
| 145325-89-9 |
| 2,7-diamino-1,8-naphthyridine |
| SCHEMBL1765925 |
| DTXSID50459726 |
| CHEMBL4513776 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1594526 | Binding affinity to pre-miR-136 RNA delta-C-bulge mutant (unknown origin) at 0.063 to 1 uM by SPR assay | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer. |
| AID1594528 | Binding affinity to pre-miR-136 RNA hairpin mutant (unknown origin) at 0.063 to 1 uM by SPR assay | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer. |
| AID1594527 | Binding affinity to pre-miR-136 RNA delta-internal loop mutant (unknown origin) at 0.063 to 1 uM by SPR assay | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer. |
| AID1594525 | Binding affinity to pre-miR-136 RNA (unknown origin) at 0.063 to 1 uM by SPR assay | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.28
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.28) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||