Compounds > 2,7-diamino-1,8-naphthyridine
Page last updated: 2024-11-12

2,7-diamino-1,8-naphthyridine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,7-diamino-1,8-naphthyridine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11240647
CHEMBL ID4513776
SCHEMBL ID1765925
MeSH IDM0528302

Synonyms (8)

Synonym
1,8-naphthyridine-2,7-diamine
[1,8]naphthyridine-2,7-diamine
AKOS006291347
145325-89-9
2,7-diamino-1,8-naphthyridine
SCHEMBL1765925
DTXSID50459726
CHEMBL4513776
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID1594526Binding affinity to pre-miR-136 RNA delta-C-bulge mutant (unknown origin) at 0.063 to 1 uM by SPR assay2019Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10
Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer.
AID1594528Binding affinity to pre-miR-136 RNA hairpin mutant (unknown origin) at 0.063 to 1 uM by SPR assay2019Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10
Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer.
AID1594527Binding affinity to pre-miR-136 RNA delta-internal loop mutant (unknown origin) at 0.063 to 1 uM by SPR assay2019Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10
Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer.
AID1594525Binding affinity to pre-miR-136 RNA (unknown origin) at 0.063 to 1 uM by SPR assay2019Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10
Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.28 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index5.08 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
ConditionIndicatedRelationship StrengthStudiesTrials
Alpha Virus Infections
[description not available]		02.0810
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.0810