cypermethrin : A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
zeta-cypermethrin : A diastereoisomeric mixture comprising the isomeric pair (1R)-cis-(alphaS)- and (1S)-trans-(alphaR)-cypermethrin together with the isomeric pair (1S)-cis-(alphaS)- and (1S)-trans-(alphaS)-cypermethrin where the ratio between the isomeric pairs lies in the range 45:55 to 55:45. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 2912 |
| CHEMBL ID | 373204 |
| CHEBI ID | 4042 |
| SCHEMBL ID | 21972 |
| MeSH ID | M0067698 |
| Synonym |
|---|
| DIVK1C_006814 |
| (+)-alpha-cyano-3-phenoxybenzyl-(+)-cis,trans-2,2-dichlorovinyl-2,2-dimethylcyclopropanecarboxylate |
| excis |
| einecs 257-842-9 |
| agrothrin |
| cymperator |
| hsdb 6600 |
| creokhin |
| cypermetryna [polish] |
| ectopor |
| cyrux |
| cympa-ti |
| (+-)-alpha-cyano-3-phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane carboxylate |
| nrdc-149 |
| basathrin |
| ecofleece sheep dip (non-op) |
| cymbush |
| fmc 45497 |
| neramethrin ec 50 |
| cypersect |
| jf 5705f |
| kordon |
| dysect |
| ambush cy |
| fury |
| cypermethrine |
| (+-)-alpha-cyano-3-phenoxybenzyl-(+-)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate |
| fmc 45806 |
| cypercare |
| exp 5598 |
| sherpa |
| sf 06646 |
| (rs)-alpha-cyano-3-phenoxybenzyl (1rs,3rs)-(1rs,3rs)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| fenom |
| ccris 2499 |
| colt |
| ustaad |
| topclip parasol |
| zeta-cypermethrin |
| neramethrin |
| demon |
| barricade 10ec |
| hilcyperin |
| 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)-, methyl ester |
| fury insecticide |
| ardap |
| wrdc149 |
| nurele |
| cypermethrin [ban] |
| wl 8517 |
| cypercopal |
| ru 27998 |
| ambush c |
| fmc 30980 |
| arrivo |
| caswell no. 268aa |
| cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester |
| brn 2422506 |
| (rs)-alpha-cyano-3-phenoxybenzyl (1rs)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| demon tc |
| kreokhin |
| epa pesticide chemical code 129064 |
| ammo (pesticide) |
| cyperkill |
| kalif super |
| yt 305 |
| cypermethrine [iso-french] |
| supercypermethrin forte |
| ccn 52 |
| mustang |
| cyperco |
| barricade (insecticide) |
| wl 43467 |
| asymmethrin |
| flectron |
| cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcycloptopanecarboxylate |
| supercypermethrin |
| cypermethrin [ansi:bsi:iso] |
| cypermethrin-25ec |
| ammo |
| pp 383 |
| ripcord |
| antiborer 3767 |
| cis-cypermethrin |
| toppel |
| cyperil |
| cypor |
| fenom (pesticide) |
| siperin |
| vucht 424 |
| rycopel |
| epa pesticide chemical code 109702 |
| nrdc 149 |
| drago |
| alpha-cyano-3-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| SPECTRUM_001862 |
| BCBCMAP01_000010 |
| BIO1_000414 |
| BIO1_000903 |
| BIO2_000318 |
| BIO2_000798 |
| BIO1_001392 |
| IDI1_034068 |
| cypermethrin (ban) |
| zetagard (tn) |
| D07763 |
| BSPBIO_001598 |
| SPECTRUM5_001858 |
| cypermethrin |
| 52315-07-8 |
| NCGC00160389-01 |
| cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| CHEBI:4042 , |
| alpha-cyano(3-phenoxyphenyl)methyl (+-)cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| NCGC00160389-03 |
| NCGC00163438-01 |
| NCGC00160389-02 |
| KBIO2_000318 |
| KBIO2_002886 |
| KBIO2_007511 |
| KBIO2_004943 |
| KBIOSS_000318 |
| KBIO3_000635 |
| KBIO2_005454 |
| KBIO1_001758 |
| KBIOGR_000318 |
| KBIO3_000636 |
| KBIOSS_002379 |
| KBIO2_002375 |
| SPECPLUS_000718 |
| cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| NCGC00160389-04 |
| NCGC00160389-05 |
| ccris 4067 |
| supermethrin |
| 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, cyano(3-phenoxyphenyl)methyl ester |
| HMS1989P20 |
| avicade |
| BMK1-H8 |
| HMS1361P20 |
| HMS1791P20 |
| .zeta.-cypermethrin |
| CHEMBL373204 |
| dudu alpha |
| .alpha.-cypermethrin |
| cypermethrin, .zeta.- |
| wl85871 |
| nsc-760420 |
| [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate |
| (s)-alpha-cyano-3-phenoxybenzyl(1rs,3rs |
| 1rs,3sr)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-carboxylate |
| (1rs)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| NCGC00160389-06 |
| NCGC00160389-07 |
| HMS3264O17 |
| tox21_300892 |
| dtxsid1023998 , |
| NCGC00254796-01 |
| dtxcid003998 |
| tox21_113579 |
| cas-52315-07-8 |
| nsc760420 |
| pharmakon1600-01503606 |
| c22h19cl2no3 |
| cypromethin |
| [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylate |
| unii-1tr49121np |
| cypermetryna |
| nsc 760420 |
| 1tr49121np , |
| FT-0603149 |
| FT-0603150 |
| AKOS015899999 |
| cypermethrin [who-dd] |
| cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-,(r)-cyano(3-phenoxyphenyl)methyl ester, (1s,3r)-rel- |
| cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-,cyano(3-phenoxyphenyl)methyl ester |
| cypermethrin [mart.] |
| cypermethrin [iso] |
| cypermethrin [mi] |
| cypermethrin [hsdb] |
| (rs)-.alpha.-cyano-3-phenoxybenzyl (1rs,3rs)-(1rs,3rs)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| CCG-213883 |
| beta cypermethrin |
| alphamethrine |
| 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid 3-phenoxy-alpha-cyano-benzyl ester |
| alpha-cyano-3-phenoxybenzyl 2-(2',2'-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylate |
| alpha-cyano-3-phenoxybenzyl 2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylate |
| alpha-cyano-3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| SCHEMBL21972 |
| tox21_113579_1 |
| NCGC00160389-09 |
| KS-5077 |
| ralothrin |
| aimcocyper |
| cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate # |
| folcord |
| prevail |
| kafil super |
| ccn52 |
| fligene ci |
| stockade |
| 137497-61-1 |
| HB0222 |
| AC-22284 |
| HMS3402P20 |
| AB00052361_02 |
| mfcd00055328 |
| cypermethrin, >=98% (hplc) |
| SR-01000872736-1 |
| sr-01000872736 |
| cypermethrin, certified reference material, tracecert(r) |
| alpha-cypermethrin, pestanal(r), analytical standard |
| cypermethrin, pestanal(r), analytical standard |
| alpha-cyano-3-phenoxybenzyl [1s-[1alpha(r*),3beta]]-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| cypermethrin 100 microg/ml in acetonitrile |
| cypermethrin 10 microg/ml in isooctane |
| cypermethrin 100 microg/ml in cyclohexane |
| SBI-0051832.P002 |
| 3-(2,2-dichloro-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid cyano-(3-phenoxy-phenyl)-methyl ester |
| FT-0773601 |
| 97955-44-7 |
| Q412024 |
| 86753-92-6 |
| cypermethrin, high effect |
| DB13721 |
| 3-(2,2-dichloro-vinyl)-2,2-dimethyl-cyclopropane carboxylic acid, cyano (3-phenoxy-phenyl) methyl ester |
| 211504-93-7 |
| fastac duo; fendona; fendona 65c; mageos; ultimate; wl 85871 |
| alpha-cypermethrin1-epimericmixture |
| cypermethrin, solid |
| alpha -cypermethrin |
| cypermethrin (mart.) |
| 3-(2,2-dichlorovinyl-2,2-dimethylcyclopropanecarboxylate) |
| (+)alpha-cyano-3-phenoxybenzyl-(+)cis,trans-2,2-dichlorovinyl-2,2-dimethylcyclopropanecarboxylate |
| pp383 |
| nrdc 166 |
| nrdc 160 |
| zetagard |
| cybil |
| cypermethrin technical |
| 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)-methyl ester |
| (rs)-alpha-cyano-3-phenoxybenzyl (1rs)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
| usepa/opp pesticide code: 109702 |
| (+-)-alpha-cyano-3-phenoxybenzyl-(+-)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate |
| (cyano(3-phenoxyphenyl)methyl |
| cynoff |
| cnn52 |
| cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethyl-cyclopropanecarboxylate. |
Cypermethrin (CMN) is a widely used artificial synthetic pesticide that causes neurotoxicity in the hippocampus. Beta-cypermethin (β-CY) is an organic compound that is widely used as a synthetic pesticide in agriculture and family.
Cypermethrin (CYP) has been identified as one kind of endocrine-disrupting chemicals (EDCs) to induce male reproduction damage. It has been administered for decades to control salmon lice (Lepeophtheirus salmonis) infestations in Atlantic salmon farming regions globally. Cypermethin and DDT have been detected in human breast milk from malaria endemic area in South Africa.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Cypermethrin (CYP) has been identified as one kind of endocrine-disrupting chemicals (EDCs) to induce male reproduction damage. " | ( MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro. Guo, QW; Wang, LS; Wang, Q; Wang, XX; Xie, JF; Xu, LC; Yao, TT; Yu, Y, 2023) | 2.65 |
| "Cypermethrin has been administered for decades to control salmon lice (Lepeophtheirus salmonis) infestations in Atlantic salmon farming regions globally. " | ( Cypermethrin exposure induces metabolic and stress-related gene expression in copepodid salmon lice (Lepeophtheirus salmonis). Braden, LM; Fast, MD; Koop, BF; Messmer, AM; Poley, JD; Whyte, SK, 2016) | 3.32 |
| "Cypermethrin and DDT have been detected in human breast milk from malaria endemic area in South Africa." | ( Biochemical investigation of cypermethrin toxicity in rabbits. Dahamna, S; Guemache, A; Harzallah, D; Sekfali, N, 2009) | 1.37 |
| "The cypermethrin has induced micronuclei in cultured cells without metabolic activation in toxic concentrations, similar effects being observed in polychromatic erythrocytes after treatment with subtoxic concentrations." | ( [Cypermethrin induction of micronuclei in mammalian somatic cells]. Bakhitova, LM; Pashin, IuV, ) | 1.52 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "s Cypermethrin could increase oxidative stress in cerebellar tissue of mice, induces the nuclear translocation of Nrf2 from the cytoplasm to the nucleus, and upregulating downstream gene of HO-1 expression. " | ( [Protective effect of proanthocyanidin on oxidative stress and mRNA expression of Nrf2 and HO-1 of mice cerebellar tissue induced by cypermethrin]. Liu, C; Zhao, W; Zhou, L; Zhou, Y, 2016) | 1.36 |
Cypermethrin treatment caused significant decrease in non enzymatic antioxidants, glutathione (GSH), vitamin E, vitamin C, increased methemoglobin formation in erythrocytes and increased their mechanical fragility. Cypermethin pretreatment potentiated the actions of pentobarbital and pentylene-tetrazole.
Endosulfan and cypermethrin were highly toxic towards eggs and larvae with mortality rates ranging from 80% to 100%.Beta-cypermethin (β-CYP) is a universally used pyrethroid pesticide with adverse effects on human health.
| Excerpt | Reference | Relevance |
|---|---|---|
| " The toxicity of cis- and trans-cypermethrin to rainbow trout was investigated and the concentrations of the two isomers in brain associated with toxic signs (excitability and loss of equilibrium) were determined." | ( The toxicity and metabolism of the pyrethroids cis- and trans-cypermethrin in rainbow trout, Salmo gairdneri. Edwards, R; Hutson, DH; Millburn, P, 1987) | 0.8 |
| " Covalent binding is often associated with toxic effects." | ( Cytotoxicity, cytogenotoxicity and allergenicity tests on certain pyrethroids. Hoellinger, H; Lecorsier, A; Leger, C; Sonnier, M, 1987) | 0.27 |
| " Concentrations of [14C]cis-cypermethrin in the brains of representative members of each of these classes of chordates were measured at toxic signs (an onset of hyperactivity followed by seizures and loss of balance/equilibrium) as an indicator of target organ sensitivity." | ( Comparative toxicity of cis-cypermethrin in rainbow trout, frog, mouse, and quail. Edwards, R; Hutson, DH; Millburn, P, 1986) | 0.86 |
| " The response of splenocytes to the mitogens phytohaemagglutin and concanavalin A, and to a T-dependent antigen (sheep red blood cells), was enhanced at 1/40 LD50 SCM, and at 1/20 and 1/14 LD50 these variables were suppressed." | ( Investigation of immunotoxicity of supercypermethrin forte in the Wistar rat. Janota, S; Kubová, J; Nyulassy, S; Tulinská, J, 1995) | 0.56 |
| "Chronic toxic effects of supermethrin on some biochemical parameters (AST, ALT, LDH, creatinine and total proteins) were investigated in 84 individuals of Japanese quail divided into four groups (control-K, experimental group I-P1, experimental group II-P2, experimental group III-P3) in the conditions of 140-day avian reproductive test." | ( [Biochemical aspects of the toxic effects of Supermethrin in a 140-day avian reproductive test]. Dudríková, E; Kovác, G; Legáth, J; Mlynarcíková, H; Porácová, J, 1995) | 0.29 |
| " Our experiments show that CY is more toxic than PERM to adult and neonatal rats." | ( Acute toxicity of two pyrethroids, permethrin, and cypermethrin in neonatal and adult rats. Cantalamessa, F, 1993) | 0.54 |
| ") were tested as toxic standards." | ( Virulence of the entomopathogenic fungus Metarhizium flavoviride Gams and Rozsypal and toxicity of diflubenzuron, fenitrothion-esfenvalerate and profenofos-cypermethrin to nontarget arthropods in Mauritania. Demba, SA; Peveling, R, 1997) | 0.49 |
| " Also IC50 values of these pesticides were compared with LD50 values obtained from the literature." | ( A new sensitive cell culture test for the assessment of pesticide toxicity. Bertheussen, K; Figenschau, Y; Yousef, MI, 1997) | 0.3 |
| "The aim of the study was to assess the immunotoxic effect of dermally applied alpha-cypermethrin in rats based on phagocytic and bactericidal activity of neutrophils of peripheral blood, and the general toxic effect based on histological and ultrastructural examination of internal organs." | ( Toxicity of dermally applied alpha-cypermethrin in rats. Halliop, J; Korczak, E; Latuszyńska, J; Luty, S; Obuchowska, D; Przylepa, E; Tochman, A, 1998) | 0.8 |
| "The aim of the study was the evaluation of the toxic effect of a two-component, preparation Nurelle D 550 EC (500 g of chlorpyrifos and 50 g cypermethrin per 1 l), administrated dermally." | ( Studies of toxicity of dermally-absorbed nurelle D 550 EC preparations. Halliop, J; Korczak, E; Latuszyńska, J; Luty, S; Obuchowska, D; Przylepa, E; Tochman, A, 1999) | 0.5 |
| " Most samples taken after the releases of azamethiphos were not toxic to test organisms in 48 h exposures and none were beyond 20 min post-release." | ( Dispersion and toxicity to non-target aquatic organisms of pesticides used to treat sea lice on salmon in net pen enclosures. Doe, K; Ernst, W; Jackman, P; Julien, G; Mackay, K; Page, F; Sutherland, T, 2001) | 0.31 |
| "The toxic effect of Cypermethrin 10 EC (0." | ( Residual toxicity of Cypermethrin in the larvae of coconut pest Oryctes rhinoceros (Coleoptera: Scarabaeidae). Venkatarajappa, P, 2001) | 0.95 |
| "Based on 48 h LD50 estimates from topical bioassays, cypermethrin was more toxic than permethrin to Helicoverpa zea (Boddie) larvae and adults; however, the two pyrethroids did not differ significantly in their relative toxicities to Spodoptera frugiperda (J." | ( Toxicity of pyrethroids and effect of synergists to larval and adult Helicoverpa zea, Spodoptera frugiperda, and Agrotis ipsilon (Lepidoptera: Noctuidae). Knowles, CO; Usmani, KA, 2001) | 0.56 |
| "Beta-cypermethrin, a synthetic pyrethroid pesticide and potential toxic pollutant, contaminating aquatic ecosystems was investigated in the present study for acute toxicity." | ( Investigation of acute toxicity of beta-cypermethrin on guppies Poecilia reticulata. Erkoç, FU; Koçak, O; Polat, H; Viran, R, 2002) | 1.1 |
| "This study determined the effects of acute cypermethrin toxicity in the rat and its dose-response characteristics The intraperitoneal LD50 of cypermethrin from the study was 44." | ( The acute intraperitoneal toxicity of cypermethrin. Iyaniwura, TT; Okonkwo, CA, 2004) | 0.86 |
| " Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated after administering orally different doses in rats and was determined as 145 mg/kg." | ( Repeated dose toxicity of alfa-cypermethrin in rats. Bhattacharyya, D; Das, S; Mandal, TK; Manna, S, 2004) | 1.12 |
| "The acute toxic effect of the pesticide cypermethrin to Daphnia magna HB was examined." | ( Toxicity of cypermethrin to Daphnia magna HB. Liu, T; Sheng, XM; Tang, HF; Wang, Y; Wu, ZB; Xiong, L, 2004) | 0.97 |
| " In cis-bifenthrin (cis-BF) and cis-permethrin (cis-PM), the 1R-cis isomer was 15-38 times more active than the 1S-cis enantiomer, while in trans-PM, the 1R-trans isomer was substantially more toxic than the 1S-trans enantiomer." | ( Separation and aquatic toxicity of enantiomers of synthetic pyrethroid insecticides. Gan, JJ; Liu, W; Qin, S, 2005) | 0.33 |
| "Compared with the toxicity test on single organism, the effects of toxic pollutants on organisms at community level are more reliable." | ( [Joint acute toxicity of fipronil and bata-cypermethrin to protozoa community]. Liu, GG; Wang, LX; Xu, HJ; Zheng, LQ, 2005) | 0.59 |
| " For both formulations, no adverse affects on zooplankton were detected, instead observed changes in zooplankton abundance and community composition displayed natural seasonal cycles of abundance." | ( Sea lice treatments on salmon farms have no adverse effects on zooplankton communities: a case study. Black, KD; Cromey, CJ; Gillibrand, PA; Willis, KJ, 2005) | 0.33 |
| " Moreover, some separate experiments indicated that this extract was safe to human and environment." | ( Efficiency of Thai derris extract and cypermethrin: toxicity and detoxification enzyme mechanism in the tropical armyworm, Spodoptera litura F. Milne, J; Ngernsiri, L; Rattanapan, A; Visetson, S, 2006) | 0.6 |
| " Endosulfan and cypermethrin were highly toxic towards eggs and larvae with mortality rates ranging from 80% to 100%." | ( Side effects of conventional and non-conventional insecticides on eggs and larvae of Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) in Argentine. Pineda, P; Schneider, MI; Smagghe, G, 2006) | 0.68 |
| "The indiscriminate use of pesticides and herbicides to increase crop productivity has aroused a great concern among the environmental and health scientists due to their adverse effects in both target as well as non-target species." | ( In vitro induction of cytotoxicity and DNA strand breaks in CHO cells exposed to cypermethrin, pendimethalin and dichlorvos. Bajpayee, M; Dhawan, A; Pandey, AK; Parmar, D; Patel, S, 2007) | 0.57 |
| " The lambda-cyhalothrin was found to be about 50 times more toxic to the fish than cypermethrin." | ( Preliminary evaluation of the acute toxicity of cypermethrin and lambda-cyhalothrin to Channa Punctatus. Kumar, A; Pandey, RS; Sharma, B, 2007) | 0.82 |
| " dimidiata, the effectiveness of the pyrethroids and the organophosphate differed in the LD50 comparison--the nymphs required much higher doses compared with the other triatomines and suggested a low susceptibility." | ( [Toxic effect of beta-cipermethrin, deltamethrin and fenitrothion in colonies of Triatoma dimidiata (Latreille, 1811) and Triatoma maculata (Erichson, 1848) (Hemiptera, Reduviidae)]. Angulo, VM; Reyes, M; Sandoval, CM, 2007) | 0.34 |
| "Cartap and cypermethrin, which are among the most widely used pesticides in many countries, are considered safe because of their low mammalian toxicity and their low persistence in the environment." | ( Aquatic toxicity of cartap and cypermethrin to different life stages of Daphnia magna and Oryzias latipes. Choi, K; Jung, J; Kim, Y; Oh, S, 2008) | 1.02 |
| " Effect assessments conducted according to European guideline for risk assessment of pesticides reveal that assessments based on acute toxicity tests are not always conservative enough to determine environmentally safe concentrations in soil." | ( Toxicity of the pesticide alpha-cypermethrin to four soil nontarget invertebrates and implications for risk assessment. Hartnik, T; Jensen, J; Sverdrup, LE, 2008) | 0.63 |
| " During five surveys of two on-farm VTS ponds, 88% of inlet and outlet water samples were toxic to Ceriodaphnia dubia." | ( Use of toxicity identification evaluations to determine the pesticide mitigation effectiveness of on-farm vegetated treatment systems. Anderson, B; Beretti, M; Bern, A; Hunt, J; Largay, B; Phillips, B; Tjeerdema, R, 2008) | 0.35 |
| "A series of calorimetric experiments were performed to investigate the toxic effects of beta-cypermethrin (BCP), bensulfuron-methyl (BSM) and prometryne (PM) on Pseudomonas putida (P." | ( Acute toxic effects of three pesticides on Pseudomonas putida monitored by microcalorimeter. Bramanti, E; Chen, HL; Maskow, T; Wang, F; Yao, J; Zaray, G, 2009) | 0.57 |
| " A pronounced toxic effect was observed at the 50-ppm concentration." | ( Genotoxic effects of the insecticide cypermethrin on the root meristem cells of sunflowers (Helianthus annuus L.). Hayirlioglu-Ayaz, S; Inceer, H; Ozcan, M, 2009) | 0.63 |
| "This study was planned and executed with the aims to explore corpus luteal primary cell culture as an "animal alternate testing system" in toxicity studies and in vitro toxic effects of cypermethrin (CY) 90% (pyrethroid) and methamidophos (MTP) 73% (organophosphate) on morphology and progesterone secretory activity of bovine corpus luteal cells and tissue." | ( Toxic effects of cypermethrin and methamidophos on bovine corpus luteal cells and progesterone production. Gill, SA; Khan, A; Khan, MZ; Rizvi, F, 2011) | 0.9 |
| " As a result, the findings showed that although pyrethroids are considered to be of low acute toxicity, they become more toxic when combined with piperonyl butoxide or tetramethrin in certain doses." | ( Repeated-dose 14-day dermal toxicity of different combinations of some synthetic pyrethroid insecticides, piperonyl butoxide, and tetramethrin in rats. Aksoy, A; Atmaca, E; Cenesiz, M; Das, YK; Gulbahar, MY; Guvenc, D; Yarim, GF; Yavuz, O, 2010) | 0.36 |
| "Pesticides often cause environmental pollution and adverse effects on human health." | ( Genotoxic effects of chlorpyrifos, cypermethrin, endosulfan and 2,4-D on human peripheral lymphocytes cultured from smokers and nonsmokers. Sandal, S; Yilmaz, B, 2011) | 0.65 |
| " Cypermethrin, a composite pyrethroid is moderately toxic to mammals." | ( Biochemical investigation of cypermethrin toxicity in rabbits. Dahamna, S; Guemache, A; Harzallah, D; Sekfali, N, 2009) | 1.55 |
| " Male of domestic rabbits Oryctolagus cuniculus (1 kg) received per week and per gavage 1/10 LD50 of Cypermetherin (ARRIVO 25%, active substance of Cypermetherin 250 g/l)." | ( Biochemical, hematological and histological parameters induced by cypermetherin toxicity in domestic rabbits. Belgeit, A; Bouriche, H; Boussahel, S; Dahamna, S; Harzallah, D; Merghem, M, 2010) | 0.36 |
| " The animals were gavaged by 1/5, 1/20 LD50 for 2 and 4 weeks respectively, and with 1/5 LD50 for 12 weeks, then sacrificed." | ( Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs. Belgeit, A; Bencheikh, F; Bouriche, H; Boussahel, S; Dahamna, S; Harzallah, D; Merghem, M, 2010) | 0.36 |
| " aegypti resting sites are treated with chemicals, even at reduced treatment coverage area, mosquitoes do not simply move to safe sites (untreated areas) following contact with the treated material." | ( Effects of irritant chemicals on Aedes aegypti resting behavior: is there a simple shift to untreated "safe sites"? Achee, NL; Arce, LM; Foggie, T; Grieco, JP; Manda, H; Shah, P, 2011) | 0.37 |
| " To further investigate the toxic effects of cypermethrin on fish, acridine orange (AO) staining was performed at 400 μg L⁻¹ cypermethrin and the result showed notable signs of apoptosis mainly in the nervous system." | ( Developmental toxicity of cypermethrin in embryo-larval stages of zebrafish. Di, J; Gu, A; Hu, F; Ji, G; Jin, J; Li, Y; Long, Y; Lu, C; Shi, X; Song, L; Wang, S; Wang, X; Xia, Y, 2011) | 0.93 |
| " An antagonistic toxic response was observed when the benthic invertebrate Chironomus dilutus was simultaneously exposed to the two contaminants in both water and sediment exposures." | ( Joint toxicity of a pyrethroid insecticide, cypermethrin, and a heavy metal, lead, to the benthic invertebrate Chironomus dilutus. Du, J; Lydy, MJ; Mehler, WT; You, J, 2011) | 0.63 |
| " These results illustrate the ameliorating effect of SA under stress conditions and reveal that SA is more effective in alleviating the toxic effects of insecticides at higher concentrations than that at lower concentrations." | ( Exogenous application of salicylic acid to alleviate the toxic effects of insecticides in Vicia faba L. Singh, A; Singh, AK; Srivastava, AK, 2013) | 0.39 |
| "Long term inhalation of toxic pesticides used for the domestic and industrial purposes have been shown to cause moderate to severe hematotoxicity and increased incidence of several marrow degenerative diseases, specifically hypoplastic bone marrow failure condition in humans." | ( Pesticide induced marrow toxicity and effects on marrow cell population and on hematopoietic stroma. Basak, P; Chaklader, M; Chatterjee, S; Chaudhuri, S; Das, P; Law, S; Pereira, JA, 2013) | 0.39 |
| "Two synthetic pyrethroid pesticides, α-cypermethrin and deltamethrin were investigated as potential toxic contaminants." | ( Comparative study on the toxicity of pyrethroids, α-cypermethrin and deltamethrin to Ceriodaphnia dubia. Ding, SY; Grocke, S; Kumar, A; Shen, MF, 2012) | 0.9 |
| " The mixture of permethrin and etofenprox was significantly less toxic than permethrin." | ( The joint toxicity of type I, II, and nonester pyrethroid insecticides. Peterson, RK; Schleier, JJ, 2012) | 0.38 |
| ", fungi that produce toxic aflatoxins." | ( Effects of a naturally occurring and a synthetic synergist on toxicity of three insecticides and a phytochemical to navel orangeworm (Lepidoptera: Pyralidae). Berenbaum, MR; Lawrance, A; Niu, G; Pollock, HS; Siegel, JP, 2012) | 0.38 |
| " The animals were gavaged by 1/5 LD50 (LD50 = 485 mg/kg b/w) for 2 and 4 weeks respectively, and with 1/20 LD50 for 12 weeks, then the animals sacrificed at the end of the experiment." | ( Evaluation of the toxicity of cypermethrin pesticide on organs weight loss and some biochemical and histological parameters. Belguet, A; Bouamra, D; Dahamna, S; Guendouz, A; Harzallah, D; Mergham, M, 2011) | 0.66 |
| "To investigate the separate and combined toxic effects of di-2-ethylhexylphthalate (DEHP) and cypermethrin (CYP) on prepubertal male rats." | ( [Single and combined toxic effects of di-2-ethylhexyl phthalate and cypermethrin on fertility and development in the the prepubertal male rats]. Cai, D; Li, X, 2012) | 0.83 |
| " Rats exposed to DEHP alone showed main toxic effect." | ( [Single and combined toxic effects of di-2-ethylhexyl phthalate and cypermethrin on fertility and development in the the prepubertal male rats]. Cai, D; Li, X, 2012) | 0.61 |
| " During the trial, ACYP was well tolerated by all animals as there were no observed clinically adverse reactions." | ( The efficacy and safety of alphacypermethrin as a pour-on treatment for water buffalo (Bubalus bubalis) infested with Haematopinus tuberculatus (Phthiraptera: Haematopinidae). Balestrieri, A; Bastianetto, E; Cimmino, R; Gokbulut, C; Neglia, G; Rufrano, D; Santoro, M; Veneziano, V, 2013) | 0.67 |
| " NAC reduced the adverse effects of α-CYP on lung tissues and improved the histological architecture of lung since it showed antioxidant, anti-inflammatory and antifibrotic effects on lung tissues." | ( Ameliorative effect of N-acetyl cysteine on alpha-cypermethrin-induced pulmonary toxicity in male rats. Arafa, MH; Atteia, HH; Mohamed, DA, 2015) | 0.67 |
| "Pyrethroids, the widely used pesticides, are highly toxic to aquatic organisms." | ( Joint toxicity of permethrin and cypermethrin at sublethal concentrations to the embryo-larval zebrafish. Liu, J; Liu, W; Ma, H; Yang, Y; Zhou, J, 2014) | 0.68 |
| " Among the tested chemicals, carbofuran was the most toxic to both the earthworm species." | ( Comparative toxicity of carbaryl, carbofuran, cypermethrin and fenvalerate in Metaphire posthuma and Eisenia fetida -a possible mechanism. Gupta, SK; Murthy, RC; Saxena, PN, 2014) | 0.66 |
| " Toxic symptoms were observed in mice treated with 40 or 80 mg/kg β-cypermethrin." | ( β-cypermethrin-induced acute neurotoxicity in the cerebral cortex of mice. An, L; Cao, D; Chen, N; Liu, L; Yang, J; Zhao, Y; Zhu, C, 2015) | 1.37 |
| " The strongest toxic effect on unengorged and engorged Ir and Dr females was exerted by D, whereas the effect of AC was weaker." | ( Comparison of the toxic effect of pyrethroids on Ixodes ricinus and Dermacentor reticulatus females. Bartosik, K; Buczek, A; Kuczyński, P, 2014) | 0.4 |
| " Conventional toxic unit analysis in phase II testing identified Cr, Cu, Ni, Pb, and Zn as the toxic metals, with cypermethrin, lambda-cyhalothrin, deltamethrin, and fipronils being the toxic organics." | ( Identifying the causes of sediment-associated toxicity in urban waterways in South China: incorporating bioavailabillity-based measurements into whole-sediment toxicity identification evaluation. Li, H; Ma, P; Yi, X; You, J, 2015) | 0.63 |
| "This study was aimed at determining the acute and chronic toxic effects of cypermethrin, propetamphos, and combined cypermethrin and propetamphos." | ( The acute and chronic toxic effect of cypermethrin, propetamphos, and their combinations in rats. Eraslan, G; Kanbur, M; Karabacak, M; Şahin, S; Siliğ, Y; Soyer Sarica, Z, 2016) | 0.94 |
| " Exposure to these substances during early development may lead to adverse behavior effects manifested at a later phase of life." | ( Developmental neurotoxic effects of two pesticides: Behavior and neuroprotein studies on endosulfan and cypermethrin. Buratovic, S; Eriksson, P; Fredriksson, A; Lee, I; Viberg, H, 2015) | 0.63 |
| " Cadmium (Cd) has been recognized as 1 of the most toxic metals and is a common contaminant in the aquatic system." | ( Cadmium potentiates toxicity of cypermethrin in zebrafish. He, B; Liu, J; Yang, Y; Ye, X, 2016) | 0.72 |
| " In result, it was determined that CYP, AMT and their combinations led to significant changes in the parameters investigated, and it was ascertained that long-term exposure to insecticides and the administration of insecticide combinations produced greater toxic effects in comparison with the administration of insecticides alone." | ( The toxic effect of cypermethrin, amitraz and combinations of cypermethrin-amitraz in rats. Eraslan, G; Kanbur, M; Karabacak, M; Şahin, S; Siliğ, Y; Soyer Sarıca, Z, 2016) | 0.76 |
| " Most urban samples would be expected to be highly toxic to benthic organisms due to the residue of SPs based on a calculation of toxic units (TUs) using toxicity data of the amphipod Hyalella azteca." | ( Occurrence, compositional distribution, and toxicity assessment of pyrethroid insecticides in sediments from the fluvial systems of Chaohu Lake, Eastern China. Bai, YS; Chen, TH; Peng, SC; Wang, JZ; Wu, Y; Xie, YW; Zhang, S; Zhang, XW, 2016) | 0.43 |
| " But little is known about assimilation, accumulation and toxic effects of BCYP in reptiles." | ( Distribution, Metabolism and Toxic Effects of Beta-Cypermethrin in Lizards (Eremias argus) Following Oral Administration. Chen, L; Di, S; Diao, J; Li, R; Xu, P; Zhou, Z, 2016) | 0.69 |
| " Treatment with betel leaf oil at these concentrations had no adverse effect on earthworm populations." | ( Developmental response of Spodoptera litura Fab. to treatments of crude volatile oil from Piper betle L. and evaluation of toxicity to earthworm, Eudrilus eugeniae Kinb. Al-Dhabi, NA; Duraipandiyan, V; Edwin, ES; Hunter, WB; Kalaivani, K; Ponsankar, A; Pradeepa, V; Sakthi-Bhagavathy, M; Selin-Rani, S; Senthil-Nathan, S; Thanigaivel, A; Vasantha-Srinivasan, P, 2016) | 0.43 |
| " Cypermethrin was the most toxic to both eggs (EHC50 in static system = 36." | ( Burrowing mayfly Ephemera orientalis (Ephemeroptera: Ephemeridae) as a new test species for pesticide toxicity. Bae, YJ; Cho, K; Khim, JS; Kim, Y; Lee, YS; Mo, HH, 2016) | 1.34 |
| " The present study aimed to determine the acute toxicity and evaluate the secondary toxic effects of a commercial formulation of cypermethrin on silkworm Philosamia ricini Hutt of Northeast India." | ( Cypermethrin Formulation (Ustad-10 EC) Induces Genotoxicity via Apoptosis, Affects Nutritional Physiology, and Modulates Immune Response in Silkworm Philosamia ricini (Lepidoptera: Saturniidae). Devi, D; Haloi, K; Kalita, MK, 2017) | 2.1 |
| " According to the maximum residue limits (MRLs) and acceptable daily intakes (ADIs), the final residues of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron, and chlorothalonil were safe for human consumption after these pesticides were applied by spraying 2 times at the dosages of 900, 750, 540, 562." | ( Evaluation of the safe use and dietary risk of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron and chlorothalonil in button mushroom. Dong, F; Du, P; He, H; Liu, X; Wu, X; Xu, J; Zhang, Y; Zheng, Y, 2017) | 0.92 |
| " Although CYP has been shown to pose toxic effects in some immune cells, as of now the immunotoxicity of CYP on immune progenitor cells has not been well studied." | ( β-Cypermethrin and its metabolite 3-phenoxybenzoic acid induce cytotoxicity and block granulocytic cell differentiation in HL-60 cells. Fu, Z; He, B; Jin, Y; Kong, B; Wang, X; Wei, L; Xie, X, 2018) | 1.2 |
| "To find the adverse effects induced by cypermethrin, the ecotoxicological model copepods Tigriopus japonicus and Paracyclopina nana were exposed under cypermethrin, which is a widely used type-II pyrethroid insecticide in agriculture." | ( Adverse effects of a synthetic pyrethroid insecticide cypermethrin on life parameters and antioxidant responses in the marine copepods Paracyclopina nana and Tigriopus japonicus. Jeong, CB; Kang, HM; Lee, JS; Lee, YH; Park, JC; Zhou, J, 2019) | 1.03 |
| " Moreover, cotreatment with an autophagy agonist, rapamycin (RAPA), partially blocked mitochondrial dysfunction and oxidative stress in the two cell types, whereas cotreatment with an autophagy inhibitor, 3-methyladenine (3-MA), augmented the abovementioned toxic effects." | ( Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress. Fu, Z; He, B; Jin, Y; Kong, B; Wang, X; Wei, L; Zhu, J, 2019) | 0.77 |
| " Therefore, it can be inferred that exposure to a mixture of the pesticides beta-cypermethrin and emamectin benzoate in the greenhouse environment may have adverse effects on the reproductive health of male mice." | ( Effect of a beta-cypermethrin and emamectin benzoate pesticide mixture on reproductive toxicity in male mice in a greenhouse environment. Chi, H; Kong, C; Li, J; Shao, L; Wang, F; Xing, J; Zhai, Q; Zhang, Y, 2020) | 1.12 |
| "Cypermethrin, a pyrethroid insecticide, may cause several adverse effects including nephrotoxicity." | ( Nephroprotective effects of curcumin loaded chitosan nanoparticles in cypermethrin induced renal toxicity in rabbits. Akhtar, B; Anwar, M; Muhammad, F; Saleemi, MK; Ur Rehman, S, 2020) | 2.23 |
| " These results demonstrated that beta-cypermethrin might have an adverse effect on the reproduction system of zebrafish through delaying gonadal development, disturbing sex hormone secretion, and affecting HPG axis gene expression." | ( Molecular mechanism of reproductive toxicity induced by beta-cypermethrin in zebrafish. Duan, C; Duan, S; He, X; Huang, Z; Jiang, J; Li, G; Liu, Y; Lu, J; Peng, X; Wang, R; Wu, Q; Yan, W; Yang, Q, 2021) | 1.13 |
| " In conclusion, Cypermethrin is found to be toxic to mammals." | ( Nephrotoxicity of cypermethrin in rats. Histopathological aspects. Alalwani, AD, 2020) | 1.24 |
| " However, most studies only focus on individual toxic effects, rather combined." | ( Environmentally relevant concentration of cypermethrin or/and sulfamethoxazole induce neurotoxicity of grass carp: Involvement of blood-brain barrier, oxidative stress and apoptosis. Guo, M; Liu, Y; Wang, Y; Xing, M; Yu, H; Zhao, H, 2021) | 0.89 |
| "Cypermethrin (CP) is a frequently used chiral pesticide comprised of different enantiomers that can induce a variable toxic response in biota, dependent on conformational change." | ( New insight into the enantioselective cytotoxicity of cypermethrin: imbalance between cell cycle and apoptosis. Ji, C; Magnuson, JT; Zhang, W; Zhao, M, 2021) | 2.31 |
| " The findings suggest that sub-lethal concentration of cypermethrin is toxic to fish." | ( Cassia fistula ameliorates chronic toxicity of cypermethrin in Catla catla. Faggio, C; Jindal, R; Sharma, R, 2021) | 1.13 |
| "The toxic effects of the insecticides chlorpyrifos and cypermethrin, and the herbicide glyphosate on the growth, biovolume and ultrastructure of the green microalgae Selenastrum capricornutum were evaluated." | ( Toxic effects of chlorpyrifos, cypermethrin and glyphosate on the non-target organism Selenastrum capricornutum (Chlorophyta). Asselborn, V; Fernández, C; Parodi, ER, 2021) | 1.15 |
| " Cypermethrin, the chosen pesticide, contaminates the aquatic environment after being washed off from the agricultural field to nearby water bodies leading to biomagnification-related perturbation of the ecological balance and overall environmental health by elevating adverse effects on non-target organisms producing toxic metabolites through biotransformation." | ( Poly lactide-co-glycolide encapsulated nano-curcumin promoting antagonistic interactions between HSP 90 and XRCC1 proteins to prevent cypermethrin-induced toxicity: An in silico predicted in vitro and in vivo approach. Bera, M; Dey, R; Dey, S; Majumder, A; Nandi, S; Samadder, A; Sow, P, 2022) | 1.84 |
| " The toxic effects were evaluated considering the increases in serum hepatic biomarkers alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total protein and albumin, and lipid peroxidation (LPO), as well as a decrease in antioxidative activity (reduced glutathione (GSH), superoxide dismutase (SOD), and catalase) and the upregulation of inflammatory cytokines (IL-1β, IL-6, and TNF-α)." | ( Hepatoprotective Effect of Curcumin Nano-Lipid Carrier against Cypermethrin Toxicity by Countering the Oxidative, Inflammatory, and Apoptotic Changes in Wistar Rats. Ahmed, RA; Alam, MI; Almoshari, Y; Alqahtani, SS; Alshahrani, S; Ashafaq, M; Bokar, IAM; Hussain, S; Jali, AM; Qadri, M; Siddiqui, R; Taha, MME, 2023) | 1.15 |
| "Beta-cypermethrin (β-CYP) is a universally used pyrethroid pesticide with adverse effects on human health." | ( Toxicity mechanism of peri-implantation pesticide beta-cypermethrin exposure on endometrial remodeling in early pregnant mice. Chen, QD; Cui, MX; Qiao, QF; Sheng, TY; Wang, CY; Wang, LQ; Zhang, YX; Zhou, YJ, 2023) | 1.67 |
| " Microbial degradation has been established as a reliable technique for mineralizing CP into less toxic chemicals." | ( Cypermethrin toxicity in the environment: analytical insight into detection methods and microbial degradation pathways. Kansal, I; Kapoor, A; Singh, R; Solanki, S, 2023) | 2.35 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "0 mg/kg) and pharmacodynamic interactions of insecticide were studied with centrally acting drugs viz." | ( Pharmacodynamic interactions of cypermethrin and centrally acting drugs in mice. Kanwar, RS; Varshneya, C, 1995) | 0.57 |
| " These pharmacokinetic events usually were higher with trans-cypermethrin-14C than with cis-cypermethrin-14C." | ( Pharmacokinetic mechanisms associated with synergism by DEF of cypermethrin toxicity in larval and adult Helicoverpa zea, Spodoptera frugiperda, and Agrotis ipsilon (Lepidoptera: Noctuidae). Knowles, CO; Usmani, KA, 2001) | 0.79 |
In combination with carbendazim clastogen, properties of imazalils and cypermethrins were potentiated compared to all other treatments and control. Female Wistar rats were given 1/25 LD50 of dimethoate by gavage, combined with the same LD50 fractions of propoxur and Cypermethrin.
| Excerpt | Reference | Relevance |
|---|---|---|
| " In this study, female Wistar rats were given 1/25 LD50 of dimethoate by gavage, combined with the same LD50 fractions of propoxur and cypermethrin or with arsenic (6." | ( Changes in the central nervous activity of rats treated with dimethoate in combination with other neurotoxicants in different phases of ontogenesis. Fazakas, Z; Lengyel, Z; Nagymajtényi, L, 2005) | 0.53 |
| "With a goal of minimal application of environmentally hazardous chemical insecticides, the larvicidal activity of cypermethrin was studied alone and in combination with the root extract of Solanum xanthocarpum against anopheline larvae." | ( Comparative efficacy of Solanum xanthocarpum extracts alone and in combination with a synthetic pyrethroid, cypermethrin, against malaria vector, Anopheles stephensi. Mohan, L; Sharma, P; Srivastava, CN, 2007) | 0.76 |
| " In combination with carbendazim clastogen, properties of imazalils and cypermethrins were potentiated compared to all other treatments and control." | ( Carbendazim combined with imazalil or cypermethrin potentiate DNA damage in hepatocytes of mice. Benković, V; Cupor, I; Horvat-Knezević, A; Lisicić, D; Mojsović-Cuić, A; Orsolić, N; Ðikić, D, 2012) | 0.88 |
| " Low doses of carbendazim in combination with low doses of imazalil or cypermethrin caused very pronounced hepatic necrosis, more than any of the three individually applied pesticides or combination of imazalil and cypermethrin." | ( Carbendazim impends hepatic necrosis when combined with imazalil or cypermethrin. Benković, V; Dikić, D; Horvat-Knežević, A; Knežević, F; Landeka, I; Lončar, G; Mojsović-Ćuić, A; Rogić, D; Teparić, R, 2012) | 0.85 |
Male Sprague-Dawley rats dosed with N-nitrosodiethylamine (NDEA) 24 h after two-thirds partial hepatectomy were treated with the pyrethroid insecticides fenvalerate, flucythrinate or cypermethrin in the diet for 20 weeks.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following oral dosing approx." | ( The metabolism of cypermethrin in man: differences in urinary metabolite profiles following oral and dermal administration. Laird, WJ; Lesser, JE; Marsh, JR; Woollen, BH, 1992) | 0.62 |
| " Using the guinea-pig flank model which has been developed to study this cutaneous phenomenon we have constructed dose-response curves to three structurally related pyrethroids (permethrin, cypermethrin and deltamethrin) and to a mixture of veratrum alkaloids (veratrine)." | ( A quantitative assessment of pyrethroid-induced paraesthesia in the guinea-pig flank model. Brock, JA; McKillop, CM; Oliver, GJ; Rhodes, C, 1987) | 0.46 |
| " When stickleback fish were tested, no mortality occurred at the lowest effective dosage in each trial." | ( Efficacy of cypermethrin for the control of mosquito larvae and pupae, and impact on non-target organisms, including fish. Helson, BV; Surgeoner, GA, 1986) | 0.65 |
| " A transient functional impairment was found in animals treated with any one of the four pyrethroids tested and in all cases this was maximal at the end of the 7 day subacute dosing regimen." | ( Intoxication with four synthetic pyrethroids fails to show any correlation between neuromuscular dysfunction and neurobiochemical abnormalities in rats. Dewar, AJ; Rose, GP, 1983) | 0.27 |
| "Male Sprague-Dawley rats dosed with N-nitrosodiethylamine (NDEA) 24 h after two-thirds partial hepatectomy were treated with the pyrethroid insecticides fenvalerate, flucythrinate or cypermethrin in the diet for 20 weeks." | ( Enhancement of altered hepatic foci in rat liver and inhibition of intercellular communication in vitro by the pyrethroid insecticides fenvalerate, flucythrinate and cypermethrin. Flodström, S; Hemming, H; Wärngård, L, 1993) | 0.67 |
| " Following dermal dosing the ratio of trans/cis cyclopropane acids is approximately 1:1, compared to 2:1 after oral administration." | ( Biological monitoring for pesticide exposure--the role of human volunteer studies. Batten, PL; Chester, G; Marsh, JR; Wilkes, MF; Woollen, BH, 1993) | 0.29 |
| " Sixteen rats per group were dosed with either deltametrin 0, 1, 5, or 10 mg/kg body wt." | ( Immunotoxicity of the pyrethroid insecticides deltametrin and alpha-cypermetrin. Claesson, MH; Madsen, C; Röpke, C, 1996) | 0.29 |
| "After a survey of the gonotrophic cycle of 5147 female Phlebotomus chinensis collected from the caves in the mountain area 1500 m above sea level in Nanping County, Sichuan Province where this sandfly was proved to be the typical predominant wild species living mostly in the wild cave at a very high density, a large cave was sprayed with alphamethrin at a dosage of 50 mg/m2 in July, 1993." | ( [Studies on the bionomics of Phlebotomus chinensis in mountain cave and its relation to control in northern Sichuan]. Gao, B; Hong, Y; Jin, C; Li, G; Su, Z; Xiong, G, 1995) | 0.29 |
| " First tier tests (structured observation, motor activity measurement, simple neurological examination) were applied after the first dose, during repeated dosing phase and in the restitution phase." | ( Neurotoxicity profile of supermethrin, a new pyrethroid insecticide. Formanek, J; Frantik, E; Hornychova, M; Kubat, J, 1995) | 0.29 |
| " In the dosage used, cypermethrin and cadmium alone caused no significant increase in the chromosomal aberrations, and lead acetate caused an increase of the numerical aberrations only." | ( Simultaneous action of cypermethrin and two environmental pollutant metals, cadmium and lead, on bone marrow cell chromosomes of rats in subchronic administration. Dési, I; Lorencz, R; Nehéz, M, 2000) | 0.94 |
| " cornicina were exposed to dung collected from calves dosed with topical preparations of deltamethrin, flumethrin, cyfluthrin, and alpha-cypermethrin." | ( Topical treatment of calves with synthetic pyrethroids: effects on the non-target dung fly Neomyia cornicina (Diptera: Muscidae). Jespersen, JB; Sommer, C; Vagn Jensen, KM, 2001) | 0.51 |
| " The dose-response relationships of males of susceptible and resistant strains to codlemone did not differ significantly." | ( Is attract-and-kill technology potent against insecticide-resistant Lepidoptera? Beslay, D; Bouvier, JC; Poullot, D; Sauphanor, B, 2001) | 0.31 |
| " However, no significant dose-response correlation could be found for either of the pesticides." | ( Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo. Giri, A; Giri, S; Prasad, SB; Sharma, GD, 2003) | 0.58 |
| " The results showed that cypermethrin and permethrin in the concentration of 10(-9)-10(-4) mol/L could inhibit the high affinity uptake of glutamate in the synaptosomes of cerebral cortex, hippocampus and striatum in a dose-response manner." | ( [Effects of pyrethroids on the glutamate uptake system in synaptic vesicle of rats]. Liu, Y; Shi, N; Wu, J; Xia, R, 1999) | 0.61 |
| "This study determined the effects of acute cypermethrin toxicity in the rat and its dose-response characteristics The intraperitoneal LD50 of cypermethrin from the study was 44." | ( The acute intraperitoneal toxicity of cypermethrin. Iyaniwura, TT; Okonkwo, CA, 2004) | 0.86 |
| " Larval mortality was observed at the higher dosed groups (0." | ( Synthetic pyrethroid cypermethrin induced cellular damage in reproductive tissues of Drosophila melanogaster: Hsp70 as a marker of cellular damage. Bajpai, VK; Chowdhuri, DK; Mukhopadhyay, I; Saxena, DK; Siddique, HR, 2006) | 0.65 |
| "To study dose-response relationship effects of mixed cypermethrin and methyl parathion on reproductive hormones, thyroid hormones, and immune functions in rats." | ( [Effects of mixed cypermethrin and methylparathion on endocrine hormone levels and immune functions in rats: I. Dose-response relationship]. Liu, P; Song, XX; Wen, WH; Yuan, WH, 2006) | 0.92 |
| " Next-generation third-instar larvae of each colony were topically dosed with technical cypermethrin or spinosad at 1 microL per larva, and mortality was recorded 24 h post-treatment." | ( Impact of spray application methodology on the development of resistance to cypermethrin and spinosad by fall armyworm Spodoptera frugiperda (JE Smith). Al-Sarar, A; Downer, RA; Hall, FR, 2006) | 0.79 |
| " The reproducibility of the method was assessed by three tests with alpha-cypermethrin against a reference strain, which produced dose-response lines that did not differ significantly (chi(2)=1." | ( Assessment of susceptibility of the poultry red mite Dermanyssus gallinae (Acari: Dermanyssidae) to some acaricides using an adapted filter paper based bioassay. Ford, HL; Thind, BB, 2007) | 0.57 |
| "A series of dose-response experiments was conducted to compare the relative sensitivities of toxicity test protocols using the amphipods Ampelisca abdita and Eohaustorius estuarius." | ( Relative sensitivities of toxicity test protocols with the amphipods Eohaustorius estuarius and Ampelisca abdita. Anderson, BS; Clark, S; Hunt, JW; Lowe, S; Phillips, BM; Tjeerdema, RS; Vorhees, J, 2008) | 0.35 |
| " The dosage of the two pesticides were (0, 1/300, 1/95 and 1/30) LD50, respectively." | ( [Studies on DNA damage of the neuron cell in rat offspring induced by cypermerthrin and methylparathrion during embryo exposure]. Liu, P; Wang, F; Wang, J; Wu, X, 2007) | 0.34 |
| "A nationwide yearly cycle of indoor residual spraying (IRS) with a pyrethroid, alphacypermethrin, at a dosage of 50 mg/m(2) was instituted in 2004 in the Democratic Republic of São Tomé and Príncipe." | ( Rapid control of malaria by means of indoor residual spraying of alphacypermethrin in the Democratic Republic of São Tomé and Príncipe. Chang, WC; Ferreira, MC; Lien, JC; Rampão, HS; Tseng, LF; Wu, CH, 2008) | 0.8 |
| "7 microg tick(-1), respectively and the steep slopes of dose-response curves indicated that the field population of these soft tick strains were homogenous in response to cypermethrin." | ( Comparative susceptibility of cypermethrin in Ornithodoros lahorensis Neuman and Argas persicus Oken (Acari: Argasidae) field populations. Abuolhassani, M; Banafshi, O; Faghihi, F; Nasirian, H; Rafinejad, J; Salarielac, S; Tavakoli, M; Telmadarraiy, Z; Vatandoost, H; Zarei, Z, 2007) | 0.82 |
| " anguillarum in our study may reflect a dose-response range that did not elicit an effect on those immune responses responsible for control and clearance of this particular pathogen." | ( Immunotoxicological effects of a sub-chronic exposure to selected current-use pesticides in rainbow trout (Oncorhynchus mykiss). Balfry, SK; Kennedy, CJ; Ross, PS; Shelley, LK, 2009) | 0.35 |
| " Dose-response bioassays were conducted on area-wide collection of bollworm populations from major host plants, while biochemical techniques were used to evaluate basic mechanisms underlying resistance." | ( Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. Achaleke, J; Brévault, T; Ghogomu, RT; Martin, T; Vaissayre, M, 2009) | 0.35 |
| " The results were tested against the concentration addition reference model using dose-response surface analyses." | ( Pesticide cocktails can interact synergistically on aquatic crustaceans. Cedergreen, N; Nørgaard, KB, 2010) | 0.36 |
| "The results of the binary dose-response surface studies showed that mixtures with prochloraz increased toxicity up to 12-fold compared with what was expected using the reference model concentration addition (CA)." | ( Pesticide cocktails can interact synergistically on aquatic crustaceans. Cedergreen, N; Nørgaard, KB, 2010) | 0.36 |
| " Blood was collected before dosing and after 24, 72, 144 hours after the treatment." | ( Biochemical investigation of cypermethrin toxicity in rabbits. Dahamna, S; Guemache, A; Harzallah, D; Sekfali, N, 2009) | 0.64 |
| "0 L ha(-1)) and double dosage (1." | ( Dissipation of cypermethrin, chlorpyriphos, and profenofos in tomato fruits and soil following application of pre-mix formulations. Gajbhiye, VT; Gupta, RK; Gupta, S; Sharma, RK, 2011) | 0.72 |
| " The avoidance of soils treated with cypermethrin by compost worms Eisenia andrei was studied here as a bioindicator of the influence of treatment dosage and the pesticide formulation in three different agricultural soils indicated by the Brazilian environmental authorities for ecotoxicological tests." | ( Earthworm (Eisenia andrei) avoidance of soils treated with cypermethrin. de Andréa, MM; de Sousa, AP, 2011) | 0.89 |
| " The use of chlorpyriphos and cypermethrin mixture at the recommended dosage does not seem to pose any hazards to the consumers, and a waiting period of 1 day is suggested to reduce the risk before consumption of green chilli." | ( Estimation of chlorpyriphos and cypermethrin residues in chilli (Capsicum annuum L.) by gas-liquid chromatography. Battu, RS; Jyot, G; Mandal, K; Singh, B, 2013) | 0.96 |
| " Therapeutics, such as antiparasitic compounds, is often administered to buffaloes based on dosage and intervals recommended for cattle because very few drugs have buffalo-specific label indications." | ( The efficacy and safety of alphacypermethrin as a pour-on treatment for water buffalo (Bubalus bubalis) infested with Haematopinus tuberculatus (Phthiraptera: Haematopinidae). Balestrieri, A; Bastianetto, E; Cimmino, R; Gokbulut, C; Neglia, G; Rufrano, D; Santoro, M; Veneziano, V, 2013) | 0.67 |
| " Full dose-response bioassays on third instar larvae were performed by topical application." | ( Resurgence of the cotton bollworm Helicoverpa armigera in northern Greece associated with insecticide resistance. Bentila, M; Kapantaidaki, D; Mironidis, GK; Morou, E; Savopoulou-Soultani, M; Vontas, J, 2013) | 0.39 |
| "Alpha-cypermethrin WG-SB showed residual efficacy (>80% mortality) for 13-15 weeks for the 20 mg/m2 dosage and 13-16 weeks for the 30 mg/m2 dosage, whereas alpha-cypermethrin WP showed residual efficacy for 11-15 weeks for the 20 mg/m2 dosage and 11-14 weeks for the 30 mg/m2 dosage on the surfaces tested." | ( Small-scale evaluation of the efficacy and residual activity of alpha-cypermethrin WG (250 g AI/kg) for indoor spraying in comparison with alpha-cypermethrin WP (50 g AI/kg) in India. Ghosh, SK; Kamaraju, R; Tiwari, S; Uragayala, S; Valecha, N, 2015) | 1.13 |
| " Three different experimental setups were applied: A standard 48h acute toxicity test, an adapted 48h test using passive dosing for constant chemical exposure concentrations, and a 14-day test." | ( Determining lower threshold concentrations for synergistic effects. Bjergager, MA; Cedergreen, N; Dalhoff, K; Kretschmann, A; Mayer, P; Nørgaard, KB, 2017) | 0.46 |
| " Although no significant differences were observed after two days of treatment with cypermethrin, a dose-response relationship in syrup consumption and locomotor activity was observed." | ( Effects of Bacillus thuringiensis strains virulent to Varroa destructor on larvae and adults of Apis mellifera. Alquisira-Ramírez, EV; Alvear-García, A; Arenas-Sosa, I; Hernández-Velázquez, VM; Peña-Chora, G; Suarez-Rodríguez, R, 2017) | 0.68 |
| " The impact of IRS can be affected by the dosage of insecticide, spray coverage, vector behavior, vector susceptibility to insecticides, and the residual efficacy of the insecticide applied." | ( Multi-country assessment of residual bio-efficacy of insecticides used for indoor residual spraying in malaria control on different surface types: results from program monitoring in 17 PMI/USAID-supported IRS countries. Belemvire, A; Caranci, A; Dengela, D; Fornadel, CM; George, K; Johns, B; Lucas, B; Norris, LC; Seyoum, A, 2018) | 0.48 |
| " The results emerged from this research are a further contribution to the knowledge of the risks of implementing higher dosage regimens of OPs-containing antiparasitic formulations." | ( In vitro and in vivo effects of chlorpyrifos and cypermethrin on blood cholinesterases in sheep. Lanusse, CE; Larsen, KE; Lifschitz, AL; Virkel, GL, 2019) | 0.77 |
| " Dose-response survival curves were generated for each insecticide using QCal software and lethal concentrations causing 50%, 90% and 95% mortality were determined." | ( Assessing insecticide susceptibility, diagnostic dose and time for the sand fly Phlebotomus argentipes, the vector of visceral leishmaniasis in India, using the CDC bottle bioassay. Bernhardt, SA; Chaubey, R; Hennings, S; Kumar Singh, S; Kushwaha, AK; Lawyer, P; Petersen, CA; Rowton, E; Shukla, A; Singh, OP; Sundar, S; Tiwary, P, 2023) | 0.91 |
| " In the present study, the median effect plot and the combination index isobologram were studied to evaluate the dose-response curve for individual and interactive impacts of chlorpyrifos (Chl), cypermethrin (Cyp), and arsenic (As) on soil dehydrogenase, a potential marker of soil health." | ( Effect of toxicological interaction of chlorpyrifos, cypermethrin, and arsenic on soil dehydrogenase activity in the terrestrial environment. Kumar, A; Nistala, S, 2023) | 1.35 |
| Role | Description |
|---|---|
| pyrethroid ester insecticide | null |
| pyrethroid ester acaricide | null |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| molluscicide | A substance used to destroy pests of the phylum Mollusca. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| organochlorine compound | An organochlorine compound is a compound containing at least one carbon-chlorine bond. |
| nitrile | A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it. |
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| cyclopropanecarboxylate ester | A carboxylic ester resulting from the formal condensation of the hydroxy group of an alcohol or phenol with the carboxy group of cyclopropanecarboxylic acid or its substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 12.5893 | 0.0040 | 23.8416 | 100.0000 | AID485290 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 28.1838 | 0.0251 | 27.9203 | 501.1870 | AID651751 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 61.4736 | 0.0060 | 38.0041 | 19,952.5996 | AID1159521; AID1159523 |
| TDP1 protein | Homo sapiens (human) | Potency | 8.0041 | 0.0008 | 11.3822 | 44.6684 | AID686978; AID686979 |
| AR protein | Homo sapiens (human) | Potency | 55.9734 | 0.0002 | 21.2231 | 8,912.5098 | AID1259243; AID1259247; AID743063 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 25.1189 | 0.0112 | 12.4002 | 100.0000 | AID1030 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 28.5638 | 0.0010 | 22.6508 | 76.6163 | AID1224839 |
| progesterone receptor | Homo sapiens (human) | Potency | 24.5804 | 0.0004 | 17.9460 | 75.1148 | AID1346795 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 4.3649 | 0.0123 | 7.9835 | 43.2770 | AID1645841 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 56.4312 | 0.0015 | 30.6073 | 15,848.9004 | AID1224841; AID1224848; AID1224849; AID1259401; AID1259403 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 54.9141 | 0.3758 | 27.4851 | 61.6524 | AID743217 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 18.3315 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982; AID720659 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 38.8762 | 0.0002 | 29.3054 | 16,493.5996 | AID743075 |
| G | Vesicular stomatitis virus | Potency | 9.7717 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 35.4813 | 0.0355 | 20.9770 | 89.1251 | AID504332 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 68.5199 | 0.0007 | 23.0674 | 1,258.9301 | AID743085 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 76.8806 | 0.0016 | 28.0151 | 77.1139 | AID1224843 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 61.6146 | 0.1434 | 27.6121 | 59.8106 | AID1159516 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.6146 | 19.7391 | 45.9784 | 64.9432 | AID1159509 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 43.6198 | 0.0578 | 21.1097 | 61.2679 | AID1159526 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 47.9545 | 0.0003 | 23.4451 | 159.6830 | AID743065; AID743067 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 54.9141 | 0.0420 | 27.3789 | 61.6448 | AID743210 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 61.1306 | 0.0006 | 27.2152 | 1,122.0200 | AID651741 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 0.0316 | 22.3146 | 100.0000 | AID588579 |
| Interferon beta | Homo sapiens (human) | Potency | 9.7717 | 0.0033 | 9.1582 | 39.8107 | AID1645842 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 9.7717 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 21.1317 | 0.0023 | 19.5956 | 74.0614 | AID651631 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 9.7717 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 9.7717 | 0.0123 | 8.9648 | 39.8107 | AID1645842 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID1111093 | Insecticidal activity against adult of Helicoverpa zea (corn earworm) assessed as mortality per insecticide vial after 24 hr | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID324522 | Increase in light chain 3-GFP+ autophagosome vesicle intensity per cell in human H4 cells at 6.0 uM after 24 hrs by high throughput fluorescence microscopy relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1104203 | Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioa | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104168 | Insecticidal activity against fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR08 assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1090747 | Insecticidal activity against Trichoplusia ni (cabbage looper) second-instar larvae infested on compound pre-treated cabbage leaf disk assessed as insect mortality measured 5 days post compound treatment under green house conditions | 2007 | Journal of agricultural and food chemistry, Sep-05, Volume: 55, Issue:18 | Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. |
| AID1111153 | Insecticidal activity against Aphis gossypii clone Auber (cotton aphid) in egg plant leaf assessed as mortality after 24 hr by leaf disk assay in presence of S,S,S-tri-n-butyl phosphorotrithioate | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID256018 | Lethal concentration required for 50% mortality in Tobacco budworm | 2005 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 15, Issue:22 | Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators. |
| AID1111090 | Resistant ratio, ratio of LC50 for F1 generation of third-instar of Helicoverpa zea (corn earworm) to LC50 for third-instar of corn earworm | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID379117 | Insecticidal activity against insecticide-resistant Blattella germanica Muncie fifth instars | 1999 | Journal of natural products, Mar, Volume: 62, Issue:3 | Annonaceous acetogenins: recent progress. |
| AID1104141 | Insecticidal activity against fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR06 assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104158 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Djalingo isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104150 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Tchollire to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104165 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Sorga isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111156 | Resistant factor, ratio of LC50 for Aphis gossypii clone Ivo (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID324418 | Increase in light chain 3-GFP+ autophagosome vesicle number per cell in human H4 cells at 6.0 uM after 24 hrs by high throughput fluorescence microscopy relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID324580 | Decrease in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 4 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1104144 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Ngong to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID379118 | Ratio of LT50 for Blattella germanica Muncie second instars to LT50 for Blattella germanica Jwax second instars | 1999 | Journal of natural products, Mar, Volume: 62, Issue:3 | Annonaceous acetogenins: recent progress. |
| AID1111147 | Synergist ratio, ratio of LC50 for Aphis gossypii clone NM1 (cotton aphid) in presence of piperonyl butoxide to LC50 for Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104138 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from tomato plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO ap | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111166 | Insecticidal activity against Aphis gossypii clone C4 (cotton aphid) in zucchini or squash leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104145 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Djalingo to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111144 | Synergist ratio, ratio of LC50 for Aphis gossypii clone Burk (cotton aphid) in presence of S,S,S-tri-n-butyl phosphorotrithioate to LC50 for Aphis gossypii clone Burk | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111148 | Synergist ratio, ratio of LC50 for Aphis gossypii clone Auber (cotton aphid) in presence of piperonyl butoxide to LC50 for Aphis gossypii clone Auber | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104157 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Gaschiga isolated from hyptis plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104137 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera Foumbot isolated from tomato plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO application m | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1082320 | Adulticidal activity against female Bemisia tabaci biotype B (sweet potato whitefly) in cucumber leaves assessed as residual contact toxicity treated for 30 secs before adult insect infestation measured after 24 hr by leaf dip bioassay | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID1104129 | Synergism factor, ratio of LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera field strain Pitoa isolated from tomato plant to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from toma | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111150 | Insecticidal activity against Aphis gossypii clone Burk (cotton aphid) in egg plant leaf assessed as mortality after 24 hr by leaf disk assay in presence of S,S,S-tri-n-butyl phosphorotrithioate | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111155 | Insecticidal activity against Aphis gossypii clone NM1 (cotton aphid) in zucchini or squash leaf assessed as mortality after 24 hr by leaf disk assay in presence of piperonyl butoxide | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111159 | Resistant factor, ratio of LC50 for Aphis gossypii clone PsP4 (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104135 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Ngong isolated from cotton plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO ap | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111088 | Resistant ratio, ratio of LC90 for F1 generation of third-instar of Helicoverpa zea (corn earworm) to LC90 for third-instar of corn earworm | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID1104139 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from maize plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO app | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104154 | Resistance factor, ratio of LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR08 to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1092231 | Insecticidal activity against Spodoptera litura third-instar larvae exposed to 0.1% compound on ventral side of larvae assessed as mortality after 24 hr post compound treatment by contact method | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Synthesis of novel 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-thiones and evaluation of their biocidal effects. |
| AID1104147 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Mokong to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1081870 | Insecticidal activity against Culex pipiens pallens (mosquito) fourth-instar larvae assessed as insect mortality measured 24 hr post compound exposure by dipping method | 2011 | Journal of agricultural and food chemistry, Feb-23, Volume: 59, Issue:4 | Design, synthesis, and insecticidal activities of novel monohalovinylated pyrethroids. |
| AID1082321 | Biotype susceptibility ratio, ratio of LC50 for female adult Bemisia tabaci biotype Q (sweet potato whitefly) to LC50 for female adult Bemisia tabaci biotype B | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID1111087 | Resistant ratio, ratio of LC90 for F1 generation of adult of Helicoverpa zea (corn earworm) to LC90 for adult of corn earworm | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID1111092 | Insecticidal activity against F1 generation of third-instar of Helicoverpa zea (corn earworm) assessed as mortality per insecticide vial after 48 hr | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID1081867 | Potency index, ratio of LC50 for cypermethrin to LC50 for test compound against Culex pipiens pallens (mosquito) fourth-instar larvae assessed as insect mortality measured 24 hr post compound exposure by dipping method | 2011 | Journal of agricultural and food chemistry, Feb-23, Volume: 59, Issue:4 | Design, synthesis, and insecticidal activities of novel monohalovinylated pyrethroids. |
| AID1111094 | Insecticidal activity against third-instar of Helicoverpa zea (corn earworm) assessed as mortality per insecticide vial after 48 hr | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID1104132 | Synergism factor, ratio of LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR06 to LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR06 in presen | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111091 | Insecticidal activity against F1 generation of adult of Helicoverpa zea (corn earworm) assessed as mortality per insecticide vial after 24 hr | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID256017 | Lethal concentration required for 50% mortality in Fall armyworm | 2005 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 15, Issue:22 | Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators. |
| AID1111158 | Resistant factor, ratio of LC50 for Aphis gossypii clone Auber (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111162 | Insecticidal activity against Aphis gossypii clone Ivo (cotton aphid) in cotton plant leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104131 | Synergism factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Home to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Home in presence of 10 microg/larva cytochrome P450 monooxygenase inhibito | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104136 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Guider isolated from cotton plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO a | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104124 | Synergism factor, ratio of LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR08 to LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR08 in presen | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104202 | Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioa | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID324579 | Decrease in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 2 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID324366 | Induction of light chain 3-GFP level in human H4 cells at 6.0 uM after 24 hrs by high throughput fluorescence microscopy relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1111157 | Resistant factor, ratio of LC50 for Aphis gossypii clone Burk (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111145 | Synergist ratio, ratio of LC50 for Aphis gossypii clone Burk (cotton aphid) in presence of piperonyl butoxide to LC50 for Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104204 | Insecticidal activity against adult female imidacloprid-susceptible Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104200 | Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104140 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Home isolated from cotton plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO app | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104153 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Home to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111151 | Insecticidal activity against Aphis gossypii clone Burk (cotton aphid) in egg plant leaf assessed as mortality after 24 hr by leaf disk assay in presence of piperonyl butoxide | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104126 | Synergism factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Ngong to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Ngong in presence of 10 microg/larva cytochrome P450 monooxygenase inhibi | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104152 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Sorga to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111152 | Insecticidal activity against Aphis gossypii clone Auber (cotton aphid) in egg plant leaf assessed as mortality after 24 hr by leaf disk assay in presence of piperonyl butoxide | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1111164 | Insecticidal activity against Aphis gossypii clone Auber (cotton aphid) in egg plant leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104162 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera Foumbot isolated from tomato plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104167 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Home isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104151 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from maize plant to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID255461 | Ability to release internal calcium stores mediated by ryanodine receptor without activating voltage-gated calcium channel of cockroach in CMT assay; na = not applicable | 2005 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 15, Issue:22 | Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators. |
| AID1081384 | Insecticidal activity against third-instar larval stage of prestarved Spodoptera litura in castor leaf assessed as mortality at 0.1% treated for 2 secs before larval infestation measured after 24 hr by feeding method | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis of nalidixic acid based hydrazones as novel pesticides. |
| AID324584 | Increase in long-lived protein degradation in human H4 cells after 4 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1111165 | Insecticidal activity against Aphis gossypii clone PsP4 (cotton aphid) in pepper plant leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104155 | Resistance factor, ratio of LD50 for fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR06 to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104128 | Synergism factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera Foumbot to LD50 for fourth-instar larval stage of Helicoverpa armigera Foumbot in presence of 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104148 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera Foumbot to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111149 | Synergist ratio, ratio of LC50 for Aphis gossypii clone Auber (cotton aphid) in presence of S,S,S-tri-n-butyl phosphorotrithioate to LC50 for Aphis gossypii clone Auber | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1090750 | Insecticidal activity against Spodoptera exigua second-instar larvae feeded on compound treated lepidopteran diet assessed as insect mortality measured 5 days post compound treatment under green house conditions | 2007 | Journal of agricultural and food chemistry, Sep-05, Volume: 55, Issue:18 | Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. |
| AID1111089 | Resistant ratio, ratio of LC50 for F1 generation of adult of Helicoverpa zea (corn earworm) to LC50 for adult of corn earworm | 2010 | Pest management science, Feb, Volume: 66, Issue:2 | Differential efficacy of three commonly used pyrethroids against laboratory and field-collected larvae and adults of Helicoverpa zea (Lepidoptera: Noctuidae) and significance for pyrethroid resistance management. |
| AID1104164 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from maize plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104170 | Insecticidal activity against fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111163 | Insecticidal activity against Aphis gossypii clone Burk (cotton aphid) in cotton plant leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104161 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Mokong isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1090753 | Insecticidal activity against Heliothis virescens (tobacco budworm) second-instar larvae infested on compound pre-treated cotton cotyledon disk assessed as insect mortality measured 5 days post compound treatment under green house conditions | 2007 | Journal of agricultural and food chemistry, Sep-05, Volume: 55, Issue:18 | Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. |
| AID1111161 | Resistant factor, ratio of LC50 for Aphis gossypii clone C9 (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID324582 | Increase in long-lived protein degradation in human H4 cells after 1 hr relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID324583 | Increase in long-lived protein degradation in human H4 cells after 2 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID379114 | Insecticidal activity against insecticide-susceptible Blattella germanica Jwax second instars | 1999 | Journal of natural products, Mar, Volume: 62, Issue:3 | Annonaceous acetogenins: recent progress. |
| AID1111168 | Insecticidal activity against Aphis gossypii clone NM1 (cotton aphid) in zucchini or squash leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID324470 | Increase in light chain 3-GFP+ autophagosome vesicle area per cell in human H4 cells at 6.0 uM after 24 hrs by high throughput fluorescence microscopy relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1104134 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Gaschiga isolated from hyptis plant assessed as mortality applied topically onto thorax 30 min after 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111167 | Insecticidal activity against Aphis gossypii clone C9 (cotton aphid) in zucchini or squash leaf assessed as mortality after 24 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104201 | Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104127 | Synergism factor, ratio of LD50 for Helicoverpa armigera field strain Guider to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Guider in presence of 10 microg/larva cytochrome P450 monooxygenase inhibitor, PBO | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104166 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Tchollire isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID324581 | Decrease in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 8 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1104125 | Synergism factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Gaschiga isolated form hyptis plant to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Gaschiga isolated from hyptis plant in pres | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104146 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Guider to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104130 | Synergism factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from maize plant to LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Pitoa isolated from maize plant in presence of | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104159 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Ngong isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID379115 | Insecticidal activity against insecticide-resistant Blattella germanica Muncie second instars | 1999 | Journal of natural products, Mar, Volume: 62, Issue:3 | Annonaceous acetogenins: recent progress. |
| AID1111160 | Resistant factor, ratio of LC50 for Aphis gossypii clone C4 (cotton aphid) to Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID324585 | Increase in long-lived protein degradation in human H4 cells after 24 hrs relative to control | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48 | Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
| AID1111154 | Insecticidal activity against Aphis gossypii clone NM1 (cotton aphid) in zucchini or squash leaf assessed as mortality after 24 hr by leaf disk assay in presence of S,S,S-tri-n-butyl phosphorotrithioate | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1082322 | Adulticidal activity against female Bemisia tabaci biotype Q (sweet potato whitefly) in cucumber leaves assessed as residual contact toxicity treated for 30 secs before adult insect infestation measured after 24 hr by leaf dip bioassay | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID256019 | Lethal concentration required for 50% mortality in Diamondback moth | 2005 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 15, Issue:22 | Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators. |
| AID1104160 | Insecticidal activity against fourth-instar larval stage of Helicoverpa armigera field strain Guider isolated from cotton plant assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104143 | Resistance factor, ratio of LD50 for fourth-instar larval stage of Helicoverpa armigera field strain Gaschiga isolated from hyptis plant to LD50 for fourth-instar larval stage of pyrethroid-susceptible Helicoverpa armigera laboratory strain BK-77 | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1104169 | Insecticidal activity against fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR06 assessed as mortality applied topically onto thorax measured after 48 hr | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1111146 | Synergist ratio, ratio of LC50 for Aphis gossypii clone NM1 (cotton aphid) in presence of S,S,S-tri-n-butyl phosphorotrithioate to LC50 for Aphis gossypii clone NM1 | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Insecticide resistance traits differ among and within host races in Aphis gossypii. |
| AID1104133 | Insecticidal activity against fourth-instar larval stage of pyrethroid-resistance Helicoverpa armigera laboratory strain GS-RR08 assessed as mortality applied topically onto thorax measured after 48 hr in presence of 3.2 microg/larva propenofos | 2009 | Pest management science, Oct, Volume: 65, Issue:10 | Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7 | High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 100 (6.20) | 18.7374 |
| 1990's | 172 (10.67) | 18.2507 |
| 2000's | 368 (22.83) | 29.6817 |
| 2010's | 698 (43.30) | 24.3611 |
| 2020's | 274 (17.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (48.40) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 33 (1.94%) | 5.53% |
| Reviews | 12 (0.71%) | 6.00% |
| Case Studies | 13 (0.77%) | 4.05% |
| Observational | 2 (0.12%) | 0.25% |
| Other | 1,637 (96.46%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||