Page last updated: 2024-11-12

fp-tztp

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

FP-TZTP: a subtype selective muscarinic cholinergic ligand [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10107360
CHEMBL ID2112939
MeSH IDM0296709

Synonyms (12)

Synonym
FT-0668870
chembl2112939 ,
bdbm50407330
424829-90-3
fp-tztp
DTXSID50435762
unii-c2lni0yp8z
3-(3-(3-fluoropropyl)thio)-1,2,5-thiadiazol-4-yl-1,2,5,6-tetrahydro-1-methylpyridine
3-(4-((3-fluoropropyl)thio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine
pyridine, 3-(4-((3-fluoropropyl)thio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl-
C2LNI0YP8Z ,
3-(3-fluoropropylsulfanyl)-4-(1-methyl-3,6-dihydro-2h-pyridin-5-yl)-1,2,5-thiadiazole
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID142923In vitro binding affinity towards Muscarinic acetylcholine receptor M1 was determined by measuring its ability to displace [3H]pirenzepine from bovine striatal membranes1995Journal of medicinal chemistry, Jan-06, Volume: 38, Issue:1
Preparation of 18F-labeled muscarinic agonist with M2 selectivity.
AID142957In vitro binding affinity towards Muscarinic acetylcholine receptor M2 was determined by measuring its ability to displace [3H]-AF-DX 384 from rat heart membranes1995Journal of medicinal chemistry, Jan-06, Volume: 38, Issue:1
Preparation of 18F-labeled muscarinic agonist with M2 selectivity.
AID204639In vitro binding affinity towards Sigma receptor type 1 was determined by measuring its ability to displace [3H](+)-pentazocine from guinea pig brain membrane1995Journal of medicinal chemistry, Jan-06, Volume: 38, Issue:1
Preparation of 18F-labeled muscarinic agonist with M2 selectivity.
AID141084In vitro binding affinity towards Muscarinic acetylcholine receptor M3 was determined by measuring its ability to displace [3H]-N-methyl- Scopolamine from guinea pig ileum1995Journal of medicinal chemistry, Jan-06, Volume: 38, Issue:1
Preparation of 18F-labeled muscarinic agonist with M2 selectivity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's16 (80.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.82 (24.57)
Research Supply Index3.09 (2.92)
Research Growth Index4.91 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (9.52%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (90.48%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]