Page last updated: 2024-08-07 23:12:15
Interleukin-5
An interleukin-5 that is encoded in the genome of mouse. [OMA:P04401, PRO:DNx]
Synonyms
IL-5;
B-cell growth factor II;
BCGF-II;
Cytotoxic T-lymphocyte inducer;
Eosinophil differentiation factor;
T-cell replacing factor;
TRF
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pulmicort | Mus musculus (house mouse) | IC50 | 26.5375 | 8 | 8 |
| sophoricoside | Mus musculus (house mouse) | IC50 | 8.3000 | 7 | 8 |
Novel analogs of N-acylhydroxyethylaminomethyl-4H-chromen-4-one scaffold as IL-5 inhibitors.Bioorganic & medicinal chemistry, , 08-15, Volume: 25, Issue:16, 2017
Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors.European journal of medicinal chemistry, , Oct-20, Volume: 139, 2017
Exploration of benzamidochromenone derivatives with conformational restrictor as interleukin-5 inhibitors.Bioorganic & medicinal chemistry, , May-15, Volume: 23, Issue:10, 2015
Design and synthesis of novel chromenone derivatives as interleukin-5 inhibitors.Bioorganic & medicinal chemistry, , May-01, Volume: 21, Issue:9, 2013
Identification of novel chromenone derivatives as interleukin-5 inhibitors.European journal of medicinal chemistry, , Volume: 59, 2013
Novel interleukin-5 inhibitors based on hydroxyethylaminomethyl-4H-chromen-4-one scaffold.Bioorganic & medicinal chemistry, , Oct-01, Volume: 20, Issue:19, 2012
The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5.Bioorganic & medicinal chemistry, , Jun-15, Volume: 18, Issue:12, 2010
Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity.Bioorganic & medicinal chemistry, , Jul-01, Volume: 18, Issue:13, 2010
Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors.European journal of medicinal chemistry, , Oct-20, Volume: 139, 2017
Exploration of benzamidochromenone derivatives with conformational restrictor as interleukin-5 inhibitors.Bioorganic & medicinal chemistry, , May-15, Volume: 23, Issue:10, 2015
Design and synthesis of novel chromenone derivatives as interleukin-5 inhibitors.Bioorganic & medicinal chemistry, , May-01, Volume: 21, Issue:9, 2013
Identification of novel chromenone derivatives as interleukin-5 inhibitors.European journal of medicinal chemistry, , Volume: 59, 2013
Novel interleukin-5 inhibitors based on hydroxyethylaminomethyl-4H-chromen-4-one scaffold.Bioorganic & medicinal chemistry, , Oct-01, Volume: 20, Issue:19, 2012
The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5.Bioorganic & medicinal chemistry, , Jun-15, Volume: 18, Issue:12, 2010
Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity.Bioorganic & medicinal chemistry, , Jul-01, Volume: 18, Issue:13, 2010