Page last updated: 2024-08-07 15:45:19
Seed linoleate 13S-lipoxygenase-1
A protein that is a translation product of the LOX1.1 gene in Glycine max. [PRO:DNx, UniProtKB:P08170]
Synonyms
EC 1.13.11.12;
Lipoxygenase-1;
L-1
Research
Bioassay Publications (17)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (22)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| aspirin | Glycine max (soybean) | IC50 | 1.3750 | 1 | 2 |
| celecoxib | Glycine max (soybean) | IC50 | 16.5850 | 1 | 2 |
| ketoprofen | Glycine max (soybean) | IC50 | 130.0000 | 1 | 1 |
| masoprocol | Glycine max (soybean) | IC50 | 11.7829 | 7 | 7 |
| rofecoxib | Glycine max (soybean) | IC50 | 50.2500 | 1 | 2 |
| methyleugenol | Glycine max (soybean) | IC50 | 33.3000 | 1 | 1 |
| masoprocol | Glycine max (soybean) | IC50 | 6.7500 | 1 | 2 |
| l 656224 | Glycine max (soybean) | IC50 | 30.0000 | 1 | 1 |
| 3',4'-dihydroxyflavone | Glycine max (soybean) | Ki | 84.5000 | 1 | 1 |
| anacardic acid | Glycine max (soybean) | IC50 | 51.9000 | 1 | 1 |
| oleic acid | Glycine max (soybean) | Ki | 22.0000 | 1 | 1 |
| caffeic acid | Glycine max (soybean) | IC50 | 301.5000 | 4 | 4 |
| quercetin | Glycine max (soybean) | Ki | 106.7000 | 1 | 1 |
| biochanin a | Glycine max (soybean) | IC50 | 100.0000 | 1 | 1 |
| apigenin | Glycine max (soybean) | Ki | 178.3000 | 1 | 1 |
| luteolin | Glycine max (soybean) | IC50 | 3.2000 | 3 | 3 |
| luteolin | Glycine max (soybean) | Ki | 121.7000 | 1 | 1 |
| linoleic acid | Glycine max (soybean) | IC50 | 8.3333 | 3 | 3 |
| 7-hydroxycoumarin | Glycine max (soybean) | IC50 | 43.0000 | 1 | 1 |
| zearalenone | Glycine max (soybean) | IC50 | 51.0000 | 1 | 1 |
| baicalein | Glycine max (soybean) | IC50 | 22.6000 | 1 | 1 |
| chrysin | Glycine max (soybean) | Ki | 19.4000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 3',4'-dihydroxyflavone | Glycine max (soybean) | Km | 163.8500 | 2 | 2 |
| 3',4'-dihydroxyflavone | Glycine max (soybean) | Vmax | 0.0090 | 2 | 2 |
| quercetin | Glycine max (soybean) | Km | 114.8000 | 2 | 2 |
| quercetin | Glycine max (soybean) | Vmax | 0.0070 | 2 | 2 |
| apigenin | Glycine max (soybean) | Km | 191.2000 | 2 | 2 |
| apigenin | Glycine max (soybean) | Vmax | 0.0090 | 2 | 2 |
| luteolin | Glycine max (soybean) | Km | 169.0500 | 2 | 2 |
| luteolin | Glycine max (soybean) | Vmax | 0.0105 | 2 | 2 |
| chrysin | Glycine max (soybean) | Km | 62.9900 | 2 | 2 |
| chrysin | Glycine max (soybean) | Vmax | 0.0055 | 2 | 2 |
| 3',4',7-trihydroxyflavone | Glycine max (soybean) | Km | 143.9300 | 2 | 2 |
| 3',4',7-trihydroxyflavone | Glycine max (soybean) | Vmax | 0.0085 | 2 | 2 |