Proteins > Seed linoleate 13S-lipoxygenase-1
Page last updated: 2024-08-07 15:45:19
Seed linoleate 13S-lipoxygenase-1
A protein that is a translation product of the LOX1.1 gene in Glycine max. [PRO:DNx, UniProtKB:P08170]
Synonyms
EC 1.13.11.12;
Lipoxygenase-1;
L-1
Research
Bioassay Publications (17)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (22)
Drugs with Inhibition Measurements
Drugs with Other Measurements
Substituted furans as potent lipoxygenase inhibitors: Synthesis, in vitro and molecular docking studies.Bioorganic chemistry, , Volume: 71, 2017
Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.European journal of medicinal chemistry, , Volume: 47, Issue:1, 2012
Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties.Bioorganic & medicinal chemistry, , Jan-15, Volume: 15, Issue:2, 2007
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.Journal of medicinal chemistry, , Mar-09, Volume: 49, Issue:5, 2006
Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases.Bioorganic & medicinal chemistry letters, , Nov-01, Volume: 15, Issue:21, 2005
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.Journal of medicinal chemistry, , Jun-06, Volume: 45, Issue:12, 2002
Synthesis and biological evaluation of fused oxepinocoumarins as free radicals scavengers.Journal of enzyme inhibition and medicinal chemistry, , Volume: 26, Issue:6, 2011
Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 17, Issue:23, 2007
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.Journal of medicinal chemistry, , Mar-09, Volume: 49, Issue:5, 2006
Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases.Bioorganic & medicinal chemistry letters, , Nov-01, Volume: 15, Issue:21, 2005
Inhibition of LOX by flavonoids: a structure-activity relationship study.European journal of medicinal chemistry, , Jan-24, Volume: 72, 2014
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.Journal of medicinal chemistry, , Mar-09, Volume: 49, Issue:5, 2006
Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases.Bioorganic & medicinal chemistry letters, , Nov-01, Volume: 15, Issue:21, 2005