Substance | Relationship Strength | Studies | Trials | Classes | Roles |
2-nitropropane 2-nitropropane: RN given refers to cpd with locant for nitro moiety in 2 position. 2-nitropropane : A secondary nitroalkane that is propane in which a hydrogen at position 2 has been replaced by a nitro group. Mainly used as a solvent (b.p. 120degreeC). | 2.1 | 1 | 0 | secondary nitroalkane | carcinogenic agent; hepatotoxic agent; polar aprotic solvent; xenobiotic |
dimethyl sulfoxide Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. | 2.07 | 1 | 0 | sulfoxide; volatile organic compound | alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger |
benzocaine Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.. dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.. benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina. | 2.1 | 1 | 0 | benzoate ester; substituted aniline | allergen; antipruritic drug; sensitiser; topical anaesthetic |
diphenylpyraline diphenylpyraline: RN given refers to parent cpd; structure. allergen : A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.. diphenylpyraline : A member of the class of piperidines that is the benzhydryl ether derivative of 1-methyl-4-hydroxypiperidine. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders. It is also used as the teoclate salt (piprinhydrinate) as an ingredient in compound preparations for the symptomatic relief of coughs and the common cold. | 2.1 | 1 | 0 | piperidines; tertiary amine | cholinergic antagonist; H1-receptor antagonist |
p-aminoazobenzene p-Aminoazobenzene: Used in the form of its salts as a dye and as an intermediate in manufacture of Acid Yellow, diazo dyes, and indulines.. 4-(phenylazo)aniline : Azobenzene substituted at one of the 4-positions by an amino group. It has a role as a dye and an allergen. | 2.17 | 1 | 0 | | |
propane Propane: A three carbon alkane with the formula H3CCH2CH3. | 2.1 | 1 | 0 | alkane; gas molecular entity | food propellant |
isoprene isoprene: used in manufacture of ''synthetic'' rubber, butyl rubber; copolymer in production of elastomers; structure. isoprene : A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds. | 2.15 | 1 | 0 | alkadiene; hemiterpene; volatile organic compound | plant metabolite |
2,5-diaminotoluene 2,5-diaminotoluene: RN given refers to parent cpd. 2-methyl-1,4-phenylenediamine : A diamine in which the two amino groups are substituted into toluene at the 2- and 5-positions. | 3.44 | 1 | 1 | diamine | allergen |
4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane: RN given refers to parent cpd; structure. 4,4'-diaminodiphenylmethane : An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group. | 1.97 | 1 | 0 | aromatic amine | allergen; carcinogenic agent |
4-phenylenediamine 4-phenylenediamine: agent hair dye responsible for contact dermatitis; RN given refers to parent cpd. 1,4-phenylenediamine : A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus. | 4.68 | 6 | 1 | phenylenediamine | allergen; dye; hapten; reagent |
disperse blue 1 [no description available] | 2.07 | 1 | 0 | anthraquinone | |
disperse orange 1 [no description available] | 2.69 | 2 | 0 | | |
dispersion yellow 3 Dispersion Yellow 3: used in carpet industry; river pollutant. 4-(2-hydroxy-5-methylphenylazo)acetanilide : An azo dye with a structure consisting of acetanilide substituted on the 4-position of the phenyl group with a 6-hydroxy-m-tolylazo group. | 2.92 | 4 | 0 | | |
disperse red 1 Disperse Red 1 : An azo dye with a structure consisting of nitrobenzene substituted on the 4-position of the phenyl group with a 4-[N-ethyl-N-(2-hydroxyethyl)]phenylazo group. | 2.69 | 3 | 0 | | |
n-isopropyl-n-phenyl-4-phenylenediamine N-isopropyl-N-phenyl-4-phenylenediamine: RN given refers to parent cpd; structure in sixth source | 2.1 | 1 | 0 | | |
disperse blue 35 disperse blue 35: not a single chemical cpd | 2.57 | 2 | 0 | | |
disperse blue 124 Disperse Blue 124: RN given refers to cpd with unknown MF. Disperse Blue 124 : A monoazo compound consisting of diazene with a 5-nitrothiazol-2-yl group attached to one nitrogen and a substituted 4-aminophenyl group attached to the other; used as a dye standard for the assay of allergy-releasing dyes in textiles. | 4.38 | 6 | 0 | 1,3-thiazoles; monoazo compound; tertiary amine | allergen; dye; hapten |
disperse blue 106 disperse blue 106: monoazo textile dye used on polyester blouses; no other info available 12/85 | 4.11 | 4 | 0 | | |
metanil yellow metanil yellow: RN given refers to parent cpd; structure. metanil yellow : An organic sodium salt having 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate as the counterion. Used in one variant of Masson's trichrome to stain collagen yellow in contrast to the red muscle, but is not in common used. | 2.17 | 1 | 0 | organic sodium salt | histological dye |
basic red 46 basic red 46: monoazoic dye used for acrylic textiles implicated in contact dermatitis | 2.17 | 1 | 0 | | |
piperidines Piperidines: A family of hexahydropyridines. | 2.1 | 1 | 0 | | |