piracetam has been researched along with Sensitivity and Specificity in 26 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a simple, fast and validated method for the determination of the new generation antiepileptic drug (AED) levetiracetam (LEV) in plasma of patients with epilepsy using high performance liquid chromatography (HPLC) with UV detection." | 7.74 | Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Mohamed, S; Riva, R, 2008) |
| "We present a simple, fast and validated method for the determination of the new generation antiepileptic drug (AED) levetiracetam (LEV) in plasma of patients with epilepsy using high performance liquid chromatography (HPLC) with UV detection." | 3.74 | Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Mohamed, S; Riva, R, 2008) |
| "Forty two had progressed to Alzheimer type dementia during a five year follow up period and were considered to have predementia Alzheimer's disease at baseline." | 2.71 | Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease? ( Scheltens, P; Verhey, FR; Visser, PJ, 2005) |
| "Levetiracetam (LEV) is an antiepileptic drug which has good safety and efficacy in neonatal seizure (NS), a common incident in neonates with weight <1500 g." | 1.48 | Determination of plasma Levetiracetam level by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS) and its application in pharmacokinetics studies in neonates. ( Horsuwan, S; Jenjirattithigarn, N; Khongkhatithum, C; Prempunpong, C; Prommas, S; Puangpetch, A; Sukasem, C; Thampratankul, L; Visudtibhan, A; Worachat, N, 2018) |
| " The proposed method was checked in bulk drugs, dosage formulations, physiological condition, and clinical investigations and excellent outcome was witnessed." | 1.40 | Development of new method for simultaneous analysis of piracetam and levetiracetam in pharmaceuticals and biological fluids: application in stability studies. ( Ahmad, M; Naseem, H; Shafi, N; Sher, N; Siddiqui, FA; Wafa Sial, A, 2014) |
| " The developed method was successfully applied to pharmacokinetic studies of piracetam in rats following single oral administration dose of 50 mg/kg." | 1.36 | Determination of piracetam in rat plasma by LC-MS/MS and its application to pharmacokinetics. ( Hu, L; Lin, D; Wang, X; Wu, H; Xu, R; Yang, X; Ye, F; Zhu, J, 2010) |
| " The active pharmaceutical ingredient was extracted from its finished dosage form (tablet) using isopropanol." | 1.32 | A validated chiral LC method for the enantioselective analysis of Levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide on amylose-based stationary phase. ( Acharyulu, PV; Gopi Chand, I; Om Reddy, G; Praveen Kumar, K; Rao, BM; Ravi, R; Shyam Sundar Reddy, B; Sivakumar, S; Srinivasu, MK, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 9 (34.62) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Omar, MA | 1 |
| Ahmed, AB | 1 |
| Abdelwahab, NS | 1 |
| Abdelrahman, MM | 1 |
| Derayea, SM | 1 |
| Linder, C | 1 |
| Hansson, A | 1 |
| Sadek, S | 1 |
| Gustafsson, LL | 1 |
| Pohanka, A | 1 |
| Jenjirattithigarn, N | 1 |
| Worachat, N | 1 |
| Horsuwan, S | 1 |
| Puangpetch, A | 1 |
| Prempunpong, C | 1 |
| Khongkhatithum, C | 1 |
| Thampratankul, L | 1 |
| Prommas, S | 1 |
| Visudtibhan, A | 1 |
| Sukasem, C | 1 |
| Kalaria, SN | 1 |
| Dahmane, E | 1 |
| Armahizer, M | 1 |
| McCarthy, P | 1 |
| Gopalakrishnan, M | 1 |
| Siddiqui, FA | 1 |
| Sher, N | 1 |
| Shafi, N | 1 |
| Wafa Sial, A | 1 |
| Ahmad, M | 1 |
| Naseem, H | 1 |
| Deeb, S | 1 |
| McKeown, DA | 1 |
| Torrance, HJ | 1 |
| Wylie, FM | 1 |
| Logan, BK | 1 |
| Scott, KS | 1 |
| Matar, KM | 1 |
| Contin, M | 1 |
| Mohamed, S | 1 |
| Albani, F | 1 |
| Riva, R | 1 |
| Baruzzi, A | 1 |
| Subramanian, NH | 1 |
| Manigandan, P | 1 |
| Jeevan, RG | 1 |
| Radhakrishnan, G | 1 |
| Blonk, MI | 1 |
| van der Nagel, BC | 1 |
| Smit, LS | 1 |
| Mathot, RA | 1 |
| Wang, X | 1 |
| Zhu, J | 1 |
| Xu, R | 1 |
| Yang, X | 1 |
| Wu, H | 1 |
| Lin, D | 1 |
| Ye, F | 1 |
| Hu, L | 1 |
| Antonilli, L | 1 |
| Brusadin, V | 1 |
| Filipponi, F | 1 |
| Guglielmi, R | 1 |
| Nencini, P | 1 |
| Oláh, E | 1 |
| Bacsói, G | 1 |
| Fekete, J | 1 |
| Sharma, VK | 1 |
| Pucci, V | 1 |
| Bugamelli, F | 1 |
| Mandrioli, R | 1 |
| Ferranti, A | 1 |
| Kenndler, E | 1 |
| Raggi, MA | 1 |
| Rao, BM | 1 |
| Ravi, R | 1 |
| Shyam Sundar Reddy, B | 1 |
| Sivakumar, S | 1 |
| Gopi Chand, I | 1 |
| Praveen Kumar, K | 1 |
| Acharyulu, PV | 1 |
| Om Reddy, G | 1 |
| Srinivasu, MK | 1 |
| Visser, PJ | 1 |
| Scheltens, P | 1 |
| Verhey, FR | 1 |
| Curticapean, A | 1 |
| Imre, S | 1 |
| Mangelings, D | 1 |
| Saevels, J | 1 |
| Vander Heyden, Y | 1 |
| Meador, KJ | 1 |
| Gevins, A | 1 |
| Loring, DW | 1 |
| McEvoy, LK | 1 |
| Ray, PG | 1 |
| Smith, ME | 1 |
| Motamedi, GK | 1 |
| Evans, BM | 1 |
| Baum, C | 1 |
| Dierckx, RA | 1 |
| Dobbeleir, A | 1 |
| Pickut, BA | 1 |
| Timmermans, L | 1 |
| Dierckx, I | 1 |
| Vervaet, A | 1 |
| Vandevivere, J | 1 |
| Deberdt, W | 1 |
| De Deyn, PP | 1 |
| Lagarde, P | 1 |
| Gheuens, EE | 1 |
| De Pooter, CM | 1 |
| De Bruijn, EA | 1 |
| van der Heyden, S | 1 |
| Chomy, F | 1 |
| Van Oosterom, AT | 1 |
| Scalliet, PG | 1 |
| Matagne, A | 1 |
| Klitgaard, H | 1 |
| Karamancheva, I | 1 |
| Staneva, T | 1 |
| Isoherranen, N | 1 |
| Roeder, M | 1 |
| Soback, S | 1 |
| Yagen, B | 1 |
| Schurig, V | 1 |
| Bialer, M | 1 |
| Mascher, H | 1 |
| Kikuta, C | 1 |
3 trials available for piracetam and Sensitivity and Specificity
| Article | Year |
|---|---|
Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase | 2005 |
Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam.
Topics: Adolescent; Adult; Carbamazepine; Cross-Over Studies; Double-Blind Method; Electroencephalography; F | 2007 |
Technetium-99m HMPAO SPET in acute supratentorial ischaemic infarction, expressing deficits as millilitre of zero perfusion.
Topics: Aged; Cerebral Infarction; Cerebrovascular Circulation; Double-Blind Method; Female; Humans; Male; O | 1995 |
23 other studies available for piracetam and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Spectrofluorimetric approach for determination of citicoline in the presence of co-formulated piracetam through fluorescence quenching of eosin Y.
Topics: Buffers; Calibration; Cytidine Diphosphate Choline; Drug Combinations; Eosine Yellowish-(YS); Fluore | 2020 |
Carbamazepine, lamotrigine, levetiracetam and valproic acid in dried blood spots with liquid chromatography tandem mass spectrometry; method development and validation.
Topics: Carbamazepine; Chromatography, Liquid; Dried Blood Spot Testing; Female; Humans; Lamotrigine; Leveti | 2018 |
Determination of plasma Levetiracetam level by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS) and its application in pharmacokinetics studies in neonates.
Topics: Chromatography, Liquid; Drug Stability; Female; Humans; Infant, Newborn; Levetiracetam; Linear Model | 2018 |
Development and validation of a HPLC-UV assay for quantification of levetiracetam concentrations in critically ill patients undergoing continuous renal replacement therapy.
Topics: Chromatography, High Pressure Liquid; Critical Illness; Drug Stability; Humans; Levetiracetam; Linea | 2018 |
Development of new method for simultaneous analysis of piracetam and levetiracetam in pharmaceuticals and biological fluids: application in stability studies.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Contami | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Mo | 2014 |
Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: application to therapeutic drug monitoring.
Topics: Adenosine; Anticonvulsants; Calibration; Chromatography, Liquid; Drug Monitoring; Drug Stability; Dr | 2008 |
Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy.
Topics: Chromatography, High Pressure Liquid; Epilepsy; Humans; Levetiracetam; Piracetam; Reproducibility of | 2008 |
Ion chromatographic determination of residual phase transfer catalyst in active pharmaceutical ingredient.
Topics: Catalysis; Chromatography, Liquid; Levetiracetam; Piracetam; Quaternary Ammonium Compounds; Reproduc | 2009 |
Quantification of levetiracetam in plasma of neonates by ultra performance liquid chromatography-tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Drug Stability; Humans; Infant, Newborn; Leve | 2010 |
Determination of piracetam in rat plasma by LC-MS/MS and its application to pharmacokinetics.
Topics: Acetonitriles; Animals; Chromatography, Liquid; Drug Stability; Linear Models; Male; Piracetam; Pyrr | 2010 |
Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma.
Topics: Anticonvulsants; Calibration; Chromatography, Thin Layer; Drug Monitoring; Humans; Isoxazoles; Lamot | 2011 |
Determination of ng/mL levetiracetam using ultra-high-performance liquid chromatography-photodiode absorbance.
Topics: Blood Proteins; Chromatography, High Pressure Liquid; Epilepsy; Humans; Hydrogen-Ion Concentration; | 2012 |
High-performance liquid chromatographic determination of Levetiracetam in human plasma: comparison of different sample clean-up procedures.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Levetiracetam; Piracetam; Reproducibi | 2004 |
A validated chiral LC method for the enantioselective analysis of Levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide on amylose-based stationary phase.
Topics: Amides; Amylose; Anticonvulsants; Butyrates; Chromatography, Liquid; Levetiracetam; Molecular Struct | 2004 |
New validated method for piracetam HPLC determination in human plasma.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Humans; Methanol; Piracetam; Sensitivity and Sp | 2007 |
Enantiomeric impurity determination of levetiracetam using capillary electrochromatography.
Topics: Calibration; Chromatography, Micellar Electrokinetic Capillary; Levetiracetam; Piracetam; Reproducib | 2006 |
[In vitro effects of piracetam on the radiosensitivity of hypoxic cells (adaptation of MTT assay to hypoxic conditions)].
Topics: Animals; Cell Count; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; In Vitro Techniques; Neurop | 1995 |
Validation of corneally kindled mice: a sensitive screening model for partial epilepsy in man.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Cornea; Disease Models, Animal; Dizocilpine Malea | 1998 |
Determination of possible impurities in piracetam using FTIR spectroscopy.
Topics: Nootropic Agents; Piracetam; Pyrrolidines; Reproducibility of Results; Sensitivity and Specificity; | 2000 |
Enantioselective analysis of levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide using gas chromatography and ion trap mass spectrometric detection.
Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Levetiracetam; Piracetam; Reproducibility of Re | 2000 |
Rapid method for the sensitive determination of piracetam in plasma by high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Piracetam; Reproduci | 1989 |