sibutramine has been researched along with Sensitivity and Specificity in 12 studies
sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The model could also be used to assess dose-response relationships." | 1.38 | Assessment of maximum weight change and duration of therapeutic effect for non-surgical treatment of obesity using an exponential model. ( Chan, LS; Kaptein, EM; Kaptein, JS, 2012) |
| " The validated method was successfully applied to a pharmacokinetic study in human." | 1.37 | Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study. ( Bae, JW; Choi, CI; Jang, CG; Lee, SY, 2011) |
| "Sibutramine was administered to 5 (five) volunteers and the excretion profile followed for 92h." | 1.35 | Analysis of sibutramine metabolites as N-trifluoroacetamide and O-trimethylsilyl derivatives by gas chromatography-mass spectrometry in urine. ( Motta, MT; Neto, FR; Padilha, MC; Pereira, HM; Sardela, VF, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, R | 1 |
| Li, L | 1 |
| Guo, L | 1 |
| Li, W | 1 |
| Shen, Q | 1 |
| Um, SY | 1 |
| Kim, KB | 1 |
| Kim, SH | 1 |
| Ju, YC | 1 |
| Lee, HS | 1 |
| Oh, Hy | 1 |
| Choi, KH | 1 |
| Chung, MW | 1 |
| Huang, Z | 1 |
| Xiao, S | 1 |
| Luo, D | 1 |
| Chen, B | 1 |
| Yao, S | 1 |
| Sardela, VF | 1 |
| Motta, MT | 1 |
| Padilha, MC | 1 |
| Pereira, HM | 1 |
| Neto, FR | 1 |
| Bae, JW | 1 |
| Choi, CI | 1 |
| Jang, CG | 1 |
| Lee, SY | 1 |
| Wang, Y | 1 |
| Zhang, WT | 1 |
| Li, ST | 1 |
| Li, Y | 1 |
| Sun, CJ | 1 |
| Shi, Y | 1 |
| Sun, C | 1 |
| Gao, B | 1 |
| Sun, A | 1 |
| Kaptein, EM | 1 |
| Chan, LS | 1 |
| Kaptein, JS | 1 |
| Künnecke, B | 1 |
| Verry, P | 1 |
| Bénardeau, A | 1 |
| von Kienlin, M | 1 |
| Bhatt, J | 1 |
| Shah, B | 1 |
| Kambli, S | 1 |
| Subbaiah, G | 1 |
| Singh, S | 1 |
| Ameta, S | 1 |
| Ara, R | 1 |
| Brennan, A | 1 |
| Chandorkar, JG | 1 |
| Kotwal, VB | 1 |
| Dhande, NS | 1 |
| Pachpor, MP | 1 |
| Pande, VV | 1 |
1 trial available for sibutramine and Sensitivity and Specificity
| Article | Year |
|---|---|
The cost-effectiveness of sibutramine in non-diabetic obese patients: evidence from four Western countries.
Topics: Adult; Age Distribution; Aged; Appetite Depressants; Cohort Studies; Coronary Disease; Cost-Benefit | 2007 |
11 other studies available for sibutramine and Sensitivity and Specificity
| Article | Year |
|---|---|
A graphene tip coupled with liquid chromatography tandem mass spectrometry for the determination of four synthetic adulterants in slimming supplements.
Topics: Appetite Depressants; Bumetanide; Chromatography, Liquid; Cyclobutanes; Dietary Supplements; Fenflur | 2017 |
Determination of the active metabolites of sibutramine in rat serum using column-switching HPLC.
Topics: Administration, Oral; Animals; Calibration; Chromatography, High Pressure Liquid; Cyclobutanes; Male | 2008 |
Simultaneous determination of sibutramine and N-Di-desmethylsibutramine in dietary supplements for weight control by HPLC-ESI-MS.
Topics: Chromatography, High Pressure Liquid; Cyclobutanes; Dietary Supplements; Reproducibility of Results; | 2008 |
Analysis of sibutramine metabolites as N-trifluoroacetamide and O-trimethylsilyl derivatives by gas chromatography-mass spectrometry in urine.
Topics: Acetamides; Cyclobutanes; Doping in Sports; Drug Stability; Female; Fluoroacetates; Gas Chromatograp | 2009 |
Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study.
Topics: Adult; Chromatography, High Pressure Liquid; Cyclobutanes; Humans; Linear Models; Male; Reproducibil | 2011 |
[Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography].
Topics: Bumetanide; Chromatography, High Pressure Liquid; Clopamide; Cyclobutanes; Food Contamination; Food, | 2010 |
Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods.
Topics: Anthraquinones; Chromatography, Liquid; Clopamide; Cyclobutanes; Diet, Reducing; Emodin; Ephedrine; | 2011 |
Assessment of maximum weight change and duration of therapeutic effect for non-surgical treatment of obesity using an exponential model.
Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Benzazepines; Body Mass Index; Body Weight; Cyclob | 2012 |
Quantitative body composition analysis in awake mice and rats by magnetic resonance relaxometry.
Topics: Animals; Anti-Obesity Agents; Body Composition; Calibration; Cross-Sectional Studies; Cyclobutanes; | 2004 |
Rapid and sensitive method for the determination of sibutramine active metabolites in human plasma by reversed-phase liquid chromatography-tandem mass spectroscopy.
Topics: Anti-Obesity Agents; Chromatography, Liquid; Cyclobutanes; Humans; Reproducibility of Results; Sensi | 2007 |
Development and validation of high performance liquid chromatography method for analysis of sibutramine hydrochloride and its impurity.
Topics: Antidepressive Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cyclobutanes | 2008 |