Proteins > Uridine-cytidine kinase 1
Page last updated: 2024-08-07 13:45:09

Uridine-cytidine kinase 1

A uridine-cytidine kinase 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9HA47]

Synonyms

UCK 1;
EC 2.7.1.48;
Cytidine monophosphokinase 1;
Uridine monophosphokinase 1

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (2)

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
uridineHomo sapiens (human)Km407.000011
cytidineHomo sapiens (human)Km131.000011

Enables

This protein enables 3 target(s):

TargetCategoryDefinition
uridine kinase activitymolecular functionCatalysis of the reaction: ATP + uridine = ADP + UMP. [RHEA:16825]
ATP bindingmolecular functionBinding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
cytidine kinase activitymolecular functionCatalysis of the reaction: ATP + cytidine = ADP + CMP. [PMID:211379, RHEA:24674]

Located In

This protein is located in 1 target(s):

TargetCategoryDefinition
cytosolcellular componentThe part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
cytoplasmcellular componentThe contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

Involved In

This protein is involved in 3 target(s):

TargetCategoryDefinition
CMP biosynthetic processbiological processThe chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate. [ISBN:0198506732]
UMP salvagebiological processAny process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis. [GOC:ecd, PMID:15096496]
CTP salvagebiological processAny process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis. [GOC:ecd, GOC:jl, PMID:10501935]