Page last updated: 2024-09-22

4-dimethylaminophenol

Description

4-dimethylaminophenol: in combination with SODIUM NITRITE antagonizes experimental cyanide poisoning; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID22174
CHEMBL ID3707216
CHEBI ID135941
SCHEMBL ID224308
MeSH IDM0073886

Synonyms (37)

Synonym
unii-x387l5559o
x387l5559o ,
619-60-3
4-(dimethylamino)phenol
phenol, 4-(dimethylamino)-
AE-562/43286954
n,n-dimethyl-4-aminophenol
p-(dimethylamino)phenol
einecs 210-604-8
phenol, p-(dimethylamino)-
dmap (antidote)
4-dimethylaminophenol
n,n-dimethyl-p-hydroxyaniline
p-hydroxy-n,n-dimethylaniline
CHEBI:135941
JVVRCYWZTJLJSG-UHFFFAOYSA-N
AKOS006220509
SCHEMBL224308
MB02001
para-dimethylaminophenol
4-(dimethylamino)phenol [who-dd]
p-dimethylaminophenol
CHEMBL3707216
mfcd01707548
DTXSID70210932
CS-W008911
Z137981254
DB13549
DS-15612
Q229950
4-(dimethylamino)phenol; 4-n,n-dimethylaminophenol; p-hydroxy-n,n-dimethylaniline
4-dimethyl amino phenol
4-dimethylamino-phenol
A868587
EN300-176799
HY-34154
PD071838

Drug Classes (2)

ClassDescription
tertiary amino compoundA compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups.
dialkylarylamine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (47)

TimeframeStudies, This Drug (%)All Drugs %
pre-199034 (72.34)18.7374
1990's11 (23.40)18.2507
2000's2 (4.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (3.64%)6.00%
Case Studies4 (7.27%)4.05%
Observational0 (0.00%)0.25%
Other49 (89.09%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (2)

ArticleYear
The acute intravenous and oral toxicity in mice, rats and guinea-pigs of 4-dimethylaminophenol (DMAP) and its effects on haematological variables.
Toxicology, May-14, Volume: 31, Issue: 2
1984
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (2)

ArticleYear
Analysis of hemoglobin derivatives by capillary isoelectric focusing and its application in the antidotal research of cyanide poisoning.
Analytical biochemistry, Jul-01, Volume: 238, Issue: 2
1996
The acute intravenous and oral toxicity in mice, rats and guinea-pigs of 4-dimethylaminophenol (DMAP) and its effects on haematological variables.
Toxicology, May-14, Volume: 31, Issue: 2
1984
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Determination of 4-dimethylaminophenol concentrations in dog blood using LC-ESI/MS/MS combined with precolumn derivatization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Dec-01, Volume: 876, Issue: 1
2008
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]