An aldo-keto reductase family 1 member A1 that is encoded in the genome of rat. [OMA:P51635, PRO:DNx]
EC 1.1.1.2;
EC 1.1.1.33;
EC 1.1.1.372;
EC 1.1.1.54;
3-DG-reducing enzyme;
Alcohol dehydrogenase [NADP(+)];
Aldehyde reductase;
Glucuronate reductase;
1.1.1.19;
Glucuronolactone reductase;
1.1.1.20
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| valproic acid | Rattus norvegicus (Norway rat) | IC50 | 53.1000 | 2 | 2 |
| tolrestat | Rattus norvegicus (Norway rat) | IC50 | 1.2100 | 1 | 1 |
| sorbinil | Rattus norvegicus (Norway rat) | IC50 | 0.8845 | 2 | 2 |
| epalrestat | Rattus norvegicus (Norway rat) | IC50 | 1.5000 | 1 | 1 |
| quercetin | Rattus norvegicus (Norway rat) | IC50 | 2.3200 | 1 | 1 |
| ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate | Rattus norvegicus (Norway rat) | IC50 | 147.8916 | 5 | 5 |