acetylcysteine has been researched along with Sensitivity and Specificity in 119 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 23 (19.33) | 18.2507 |
2000's | 69 (57.98) | 29.6817 |
2010's | 24 (20.17) | 24.3611 |
2020's | 3 (2.52) | 2.80 |
Authors | Studies |
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Hara, Y; Inoue, R; Mori, Y; Morii, T; Sato, Y; Shimizu, S; Takahashi, N; Tominaga, M; Yamamoto, S; Yoshida, T | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Chomchai, C; Chomchai, S; Mekavuthikul, P; Phuditshinnapatra, J | 1 |
Fujita, M; Kasahara, T; Sato, A; Wanibuchi, S; Yamamoto, Y | 1 |
Akrawi, SH; Nair, A; Shinu, P; Singh, VA; Venugopala, KN | 1 |
Akhlaq, A; Campochiaro, PA; Hafiz, G; Kong, X; Wehling, D | 1 |
Graudins, A; Sivilotti, MLA; Wong, A | 1 |
Nguyen, V | 1 |
Chan, BY; Lee, HH; Leung, DC; Ling, WH; Mak, CM; Ng, CW; Tsang, HM | 1 |
Cunha, EA; de Morais, CG; de Souza Ribeiro, C; Dietze, R; Ferro E Silva, RR; Lecco, R; Maia, R; Palaci, M; Peres, RL; Ribeiro, MO; Vianna, S; Vinhas, SA | 1 |
Hongwei, H; Qingyuan, H; Wei, X; Xiaotao, Z | 1 |
Chomchai, C; Chomchai, S; Lawattanatrakul, N | 1 |
Chomchai, C; Chomchai, S | 1 |
Jayasree, K; Sara George, P; Saraswathy Veena, V; Sujathan, K | 1 |
Green, JP; Johnson, DW; Nettel-Aguirre, A; Rumack, BH; Sivilotti, ML; Spyker, DA; Victorino, C; Yarema, MC | 1 |
Chen, JG; Egner, PA; Friesen, MD; Gange, SJ; Groopman, JD; Kensler, TW | 1 |
Dekant, W; Kellert, M; Kopp, EK; Sieber, M | 1 |
Angerer, J; Boettcher, MI; Bolt, HM; Drexler, H; Hartmann, EC | 1 |
Bartolucci, GB; Carrieri, M; Corsetti, F; Livieri, M; Paci, E; Pigini, D; Sisto, R; Tranfo, G | 1 |
Born, E; Goswami, PC; Itani, H; Keen, HL; Liu, X; Sarsour, EH; Sigmund, CD | 1 |
Fawcett, JP; Krittaphol, W; McDowell, A; Mikov, M; Thomson, CD; Tucker, IG | 1 |
Choi, MM; Dong, C; Dong, W; Shuang, S | 1 |
Kraus, T; Ochsmann, E; Reska, M; Schettgen, T | 1 |
Chen, S; Mei, Y; Song, S; Ye, F; Ye, Y | 1 |
Caneva, E; Colombi, A; Di Fabio, D; Meroni, G; Pappini, M; Pitton, M; Rubino, FM; Santaniello, E | 1 |
Gui, Y; Jia, J; Li, S; Liu, G; Liu, Y; Lu, C; Yu, C; Zhang, M | 1 |
Bertazzi, PA; Campo, L; Consonni, D; Fustinoni, S; Mercadante, R; Mielzynska, D | 1 |
Andrade, CF; Oliveira, E; Rabello, A; Saliba, SW | 1 |
Grant, AL; Kotapati, S; Matter, BA; Tretyakova, NY | 1 |
Aono, A; Azuma, Y; Kokuto, H; Kubota, M; Kudoh, S; Mitarai, S; Mori, T; Morimoto, K; Nagasawa, T; Nagayama, N; Ogata, H; Okumura, M; Sejimo, A; Sugahara, K; Toyota, E; Ueyama, M; Yamane, A; Yano, R; Yi, R; Yoshiyama, T | 1 |
Borrelli, MJ; Brown, AT; Chaudhuri, S; Jambhekar, K; James, LP; McCullough, S; Ou, X; Pandey, T | 1 |
Chiang, SY; Huang, YF; Shih, WC; Uang, SN; Wu, CF; Wu, KY | 1 |
Münch, G; Ooi, L; Srikanth, V; Wild, R | 1 |
Davis, F; Duarte, AJ; Esteves da Silva, JC; Gonçalves, HM; Higson, SP | 1 |
Aloisi, C; Arena, A; Baldari, S; Buemi, F; Buemi, M; Giardina, C; Lacquaniti, A; Lupica, R; Murè, G; Visalli, C | 1 |
Bishai, WR; Chaisson, RE; De Queiroz Mello, FC; Dos Anjos Filho, L; Fonseca, LS; Kritski, AL; Manabe, YC; Scott, CP; Thornton, CG | 1 |
Chen, L; Cohen, B; Jin, X; Li, G; Li, H; Li, Y; Melikian, AA; Mu, R; Qu, Q; Shore, R; Wang, Y; Yin, S; Zhang, X | 1 |
Lindstrom, AB; Rappaport, SM; Troester, MA; Waidyanatha, S | 1 |
Baldock, C; De Deene, Y; Healy, BJ; Hurley, C; Mather, M; Venning, A; Vergote, K | 1 |
Arakawa, R; Moriwaki, H; Noda, T; Shimizu, M; Tanaka, M; Tsujimoto, Y; Warashina, M; Watanabe, A | 1 |
Cavalieri, EL; Jankowiak, R; Markushin, Y; Small, GJ | 1 |
Demirtürk, L; Diler, M; Oncül, O; Ozel, M; Tarçin, O; Yazgan, Y; Yildirim, S | 1 |
Vaes, WH; van Rooijen, HJ; Vermeulen, M | 1 |
Günter, S; Wätzig, H | 1 |
Acampora, A; Genovese, G; Miraglia, N; Pieri, M; Sannolo, N; Soleo, L | 1 |
Gilch, G; Schepers, G; Scherer, G; Urban, M; van Miert, E | 1 |
Chen, LC; Cohen, BS; Jin, X; Li, G; Li, K; Li, Y; Melikian, AA; Mu, R; Qu, Q; Shore, R; Xu, B; Yan, H; Yin, S; Zhang, X | 1 |
Allen, SJ; Cox, CS; Fischer, UM; Laine, GA; Mehlhorn, U; Stewart, RH | 1 |
Ben Shlomo, I; Eyali, V; Goldman, S; Leibovitz, S; Shalev, E; Weiss, A | 1 |
Malmberg, P; Nygren, H; Sahlin, H | 1 |
Chang, YC; Liao, PC; Lin, LC; Shih, TS; Tyan, YC | 1 |
Faddy, SC | 1 |
Li, YJ; Liao, PC; Lin, LC; Shih, JF; Shih, TS | 1 |
Averbukh, M; Averbukh, Z; Berman, S; Dishy, V; Efrati, S; Feldman, L; Golik, A; Kachko, L; Weissgarten, J | 1 |
Atienza, MP; Broseta Viana, L; Fernández-Fúnez, A; Polo-Romero, FJ; Sánchez Gascón, F | 1 |
Hu, CW; Li, CM; Wu, KY | 1 |
Alary, J; Debrauwer, L; Guéraud, F; Martins, N; Peiro, G; Rathahao, E | 1 |
Cataldi, TR; Nardiello, D | 1 |
Ferrari, M; Ghittori, S; Imbriani, M; Maestri, L; Negri, S | 1 |
Alvarez-Sánchez, R; Dekant, W; Mally, A; Pähler, A; Völkel, W; Weick, I | 1 |
Chakravorty, S; Dudeja, M; Hanif, M; Tyagi, JS | 1 |
Bertazzi, PA; Bonzini, M; Buratti, M; Campo, L; Colombi, A; Consonni, D; Desideri, A; Farmer, PB; Foà, V; Fontana, V; Fustinoni, S; Garte, S; Levy, LS; Merlo, DF; Pala, M; Pesatori, AC; Valerio, F | 1 |
Dekant, W; Pähler, A; Scholz, K; Völkel, W | 1 |
Curci, S; Gerbino, A; Hofer, AM; Pozzan, T; Ruder, WC; Zaccolo, M | 1 |
Barreiro, E; Gáldiz, JB; Gea, J; Hussain, SN; Sánchez, D | 1 |
Ardia, A; De Backer, W; Decramer, M; Dekhuijzen, PN; Del Donno, M; Lankhorst, I; Olivieri, D; Pellegrino, R; Troosters, T; van Herwaarden, C; van Schayck, CP | 1 |
Alary, J; Bernard, H; Bories, G; Canlet, C; Créminon, C; Debrauwer, L; Drumare, MF; Guéraud, F; Peiro, G; Rathahao, E; Wal, JM | 1 |
Foth, H; Glahn, F; Stehfest, E; Torky, A | 1 |
Abu-El-Ardat, K; Diab-Assaf, M; Harakeh, S; Khalife, J; Niedzwiecki, A; Rath, M | 1 |
Bagshaw, SM; Ghali, WA; Manns, BJ; McAlister, FA | 1 |
Akan, P; Camsari, T; Celik, A; Ormen, M; Sarioglu, S; Yenicerioglu, Y; Yilmaz, O | 1 |
Ancha, H; Harty, RF; Lightfoot, S; Siddiqui, A; Stewart, CA; Tedesco, D | 1 |
Bieri, M; Bürgi, T | 1 |
Ak, M; Mrowietz, U; Schmidt, TJ | 1 |
Kellert, M; Scholz, K; Sieber, M; Voelkel, W; Wagner, S | 1 |
Dong, G; Jing, H; Luo, L; Shao, H; Yin, R; Zhu, J | 1 |
Feng, S; Hagedorn, HW; Kinser, RD; Liang, Q; Roethig, HJ; Sarkar, M; Scherer, G; Urban, M | 1 |
Banks, S; Danner, RL; Gonzales, DA; Kern, SJ; Natanson, C; Norsworthy, KJ; Sieving, PC; Star, RA | 1 |
Alt, A; Kraus, T; Musiol, A; Schettgen, T | 1 |
Powell, SR | 1 |
Boogaard, PJ; van Sittert, NJ | 1 |
Baak, JP; Beliën, JA; Braakhuis, BJ; Copper, MP; Snow, GB | 1 |
Dey, MS; Down, JA; Myers, N; Zwadyk, P | 1 |
Aigner, A; Jäger, M; Weber, P; Wolf, S | 1 |
Cui, T; Tang, XY; Wu, YQ; Yu, AR; Zhang, J | 1 |
Beulink, GD; Boogaard, PJ; van Sittert, NJ | 1 |
Prestera, T; Talalay, P; Wade, KL; Zhang, Y | 1 |
Maes, RF | 1 |
Ercal, N; Hammond, TC; Matthews, RH; Oztezcan, S; Spitz, DR | 1 |
Dehnen, W; Dunemann, L; Einig, T | 1 |
Groopman, JD; Musser, SM; Scholl, PF | 1 |
Ghittori, S; Imbriani, M; Maestri, L | 1 |
Eskinja, M; Lamprecht, G; Scherer, G; Schmid, ER | 1 |
Angerer, J; Göen, T; Käfferlein, HU; Krämer, A | 1 |
Edelbroek, PM; Vermeij, TA | 1 |
Frölich, JC; Rossa, S; Sandmann, J; Tsikas, D | 1 |
Dab, W; Dor, F; Empereur-Bissonnet, P; Zmirou, D | 1 |
Hu, P; Kagan, M; Li, H; Melikian, AA; O'Connor, R; Prahalad, AK; Thompson, S | 1 |
Dekant, W; Pähler, A; Völkel, W | 1 |
Hu, P; Melikian, AA; Meng, M; O'Connor, R; Thompson, SM | 1 |
Angerer, J; Käfferlein, HU | 1 |
Chassaing, C; Gonin, J; Wainer, IW; Wilcox, CS | 1 |
Allué, JA; Celma, C; Obach, R; Peraire, C; Pruñonosa, J | 1 |
Chen, L; Cohen, B; Jin, X; Kagan, MR; Li, G; Li, H; Li, K; Li, Y; Melikian, AA; Meng, M; Mu, R; Qu, Q; Shore, R; Winnik, W; Yin, S | 1 |
Angerer, J; Göen, T; Käfferlein, HU; Müller, J; Wrbitzky, R | 1 |
Adams, J; Chau, V; Elliott, PJ; Lightcap, ES; McCormack, TA; Pien, CS | 1 |
Hata, T; Hayashibara, T; Honda, M; Joh, T; Kamihira, S; Maeda, T; Miyazaki, Y; Mori, N; Nohda, K; Sugahara, K; Tawara, M; Tomonaga, M; Tsuruda, K; Yamada, Y | 1 |
Andreoli, R; Bergamaschi, E; De Palma, G; Manini, P; Mutti, A; Niessen, WM | 1 |
Nakagomi, M; Suzuki, E | 1 |
Mascher, DG; Mascher, HJ; Scherer, G; Schmid, ER | 1 |
Gee, SJ; Hammock, BD; Jaeger, LL; Jones, AD; Langó, J; Lohse, C; Sanborn, JR; Staimer, N | 1 |
Campíns-Falcó, P; Molins-Legua, C; Sevillano-Cabeza, A; Tortajada Genaro, LA | 1 |
Brugnone, F; Maestri, L; Perbellini, L; Romani, S; Veronese, N | 1 |
de Groot, J; Hageman, GJ; Mykkänen, H; Rauma, AL; Törrönen, R; van Herwijnen, MH; Verhagen, H; Versluis-de Haan, G | 1 |
Bahadori, M; Farnia, P; Farnia, PK; Ganavi, J; Ghazisaeedi, K; Gheydi, M; Masjedi, MR; Mohammadi, F; Tabatabee, DJ; Velayati, AA; Zarifi, Z | 1 |
Makino, N; Sugano, M; Tomita, H; Tsuchida, K | 1 |
Hiraku, Y; Kawanishi, S; Murata, M | 1 |
Beard, RH; Farrar, HC; James, LP; Wells, E | 1 |
Gabard, B; Mascher, H | 1 |
4 review(s) available for acetylcysteine and Sensitivity and Specificity
Article | Year |
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Capillary electrophoresis-a high performance analytical separation technique.
Topics: Acetylcysteine; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Acetylcysteine in the prevention of contrast-induced nephropathy: a case study of the pitfalls in the evolution of evidence.
Topics: Acetylcysteine; Acute Kidney Injury; Contrast Media; Controlled Clinical Trials as Topic; Female; Humans; Male; Premedication; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Treatment Outcome | 2006 |
A meta-analysis of N-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity.
Topics: Acetylcysteine; Aged; Cluster Analysis; Contrast Media; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; Models, Biological; Publication Bias; Randomized Controlled Trials as Topic; Regression Analysis; Renal Dialysis; Risk Factors; Sensitivity and Specificity | 2007 |
Validity of biomarkers in environmental health studies: the case of PAHs and benzene.
Topics: Acetylcysteine; Benzene; Biomarkers; DNA Adducts; Environmental Exposure; Environmental Health; Humans; Hydrocarbons, Aromatic; Hydrocarbons, Cyclic; Pyrenes; Risk Assessment; Sensitivity and Specificity; Sorbic Acid | 1999 |
7 trial(s) available for acetylcysteine and Sensitivity and Specificity
Article | Year |
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Locus-Level Changes in Macular Sensitivity in Patients with Retinitis Pigmentosa Treated with Oral N-acetylcysteine.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Female; Free Radical Scavengers; Humans; Macula Lutea; Male; Middle Aged; Prospective Studies; Retinitis Pigmentosa; Retrospective Studies; Sensitivity and Specificity; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult | 2021 |
Can neutrophil gelatinase-associated lipocalin help depict early contrast material-induced nephropathy?
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Contrast Media; Creatinine; Diagnostic Imaging; Enzyme-Linked Immunosorbent Assay; Female; Gelatinases; Glomerular Filtration Rate; Humans; Iopamidol; Kidney Diseases; Lipocalins; Male; Meglumine; Middle Aged; Organometallic Compounds; Proportional Hazards Models; Prospective Studies; Radiopharmaceuticals; Risk Factors; ROC Curve; Sensitivity and Specificity; Sodium Bicarbonate; Sodium Chloride | 2013 |
Does N-acetyl cystein affect the sensitivity and specificity of Helicobacter pylori stool antigen test?
Topics: Acetylcysteine; Administration, Oral; Adult; Antigens, Bacterial; Expectorants; Feces; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity | 2003 |
Quality control of spirometry: a lesson from the BRONCUS trial.
Topics: Acetylcysteine; Aged; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality Control; Reference Values; Respiratory Function Tests; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Spirometry | 2005 |
Determination of N-acetylcysteine in human plasma by liquid chromatography coupled to tandem mass spectrometry.
Topics: Acetylcysteine; Calibration; Chromatography, Liquid; Humans; Mass Spectrometry; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2000 |
Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid.
Topics: Acetylcysteine; Antioxidants; Biomarkers; Case-Control Studies; Diet, Vegetarian; Eating; Female; Garlic; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Patient Compliance; Plants, Medicinal; Sensitivity and Specificity | 2001 |
Endogenous plasma N-acetylcysteine and single dose oral bioavailability from two different formulations as determined by a new analytical method.
Topics: Acetylcysteine; Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Dosage Forms; Humans; Male; Sensitivity and Specificity | 1991 |
108 other study(ies) available for acetylcysteine and Sensitivity and Specificity
Article | Year |
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Nitric oxide activates TRP channels by cysteine S-nitrosylation.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Chickens; Cysteine; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Nitrogen Compounds; Protein Binding; Sensitivity and Specificity; Signal Transduction; Sulfhydryl Compounds; Time Factors; Transient Receptor Potential Channels | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Sensitivity of dose-estimations for acute acetaminophen overdose in predicting hepatotoxicity risk using the Rumack-Matthew Nomogram.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Male; Middle Aged; Nomograms; Retrospective Studies; Sensitivity and Specificity; Young Adult | 2022 |
The amino acid derivative reactivity assay with fluorescence detection and its application to multi-constituent substances.
Topics: Acetylcysteine; Alanine; Animal Testing Alternatives; Dermatitis, Contact; Fluorometry; Models, Theoretical; Naphthalenes; Organic Chemicals; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Sensitivity and Specificity | 2019 |
Papain-cetylpyridinium chloride and pepsin-cetylpyridinium chloride; two novel, highly sensitive, concentration, digestion and decontamination techniques for culturing mycobacteria from clinically suspected pulmonary tuberculosis cases.
Topics: Acetylcysteine; Bacteriological Techniques; Cetylpyridinium; Culture Media; Humans; Mycobacterium tuberculosis; Papain; Pepsin A; Sensitivity and Specificity; Specimen Handling; Sputum; Tuberculosis, Pulmonary | 2020 |
Accuracy of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity in modified-release paracetamol overdose.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Alanine Transaminase; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Humans; Male; Middle Aged; Retrospective Studies; Sensitivity and Specificity; Young Adult | 2017 |
Calculated decisions: King's College Criteria for Acetaminophen Toxicity
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Biomarkers; Decision Making; Humans; Liver Failure, Acute; Liver Transplantation; Prognosis; Sensitivity and Specificity; Time Factors | 2018 |
Performance evaluation of five commercial assays for detection of acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Bilirubin; Hemolysis; Humans; Immunoenzyme Techniques; Linear Models; Reproducibility of Results; Sensitivity and Specificity | 2019 |
Contribution of the Ogawa-Kudoh swab culture method to the diagnosis of pulmonary tuberculosis in Brazil.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Bacteriological Techniques; Brazil; Humans; Middle Aged; Prospective Studies; Retrospective Studies; Sensitivity and Specificity; Sodium Hydroxide; Sputum; Tuberculosis, Pulmonary; Young Adult | 2013 |
Simultaneous measurement of N-Acetyl-S-(2-cyanoethyl)-cysteine and N-acetyl-S-(2-hydroxyethyl)-cysteine in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Acetonitriles; Acetylcysteine; Chromatography, High Pressure Liquid; Drug Stability; Formates; Humans; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization | 2014 |
Acetaminophen Psi Nomogram: a sensitive and specific clinical tool to predict hepatotoxicity secondary to acute acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Humans; Nomograms; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Thailand | 2014 |
Predicting acute acetaminophen hepatotoxicity with acetaminophen-aminotransferase multiplication product and the Psi parameter.
Topics: Acetaminophen; Acetylcysteine; Adult; Alanine Transaminase; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Humans; Likelihood Functions; Male; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Thailand; Time Factors; Young Adult | 2014 |
Comparative analysis of cell morphology in sputum samples homogenized with dithiothreitol, N-acetyl-L cysteine, Cytorich(®) red preservative and in cellblock preparations to enhance the sensitivity of sputum cytology for the diagnosis of lung cancer.
Topics: Acetylcysteine; Cytodiagnosis; Dithiothreitol; DNA, Neoplasm; Early Detection of Cancer; Humans; Immunohistochemistry; Lung; Lung Neoplasms; Preservatives, Pharmaceutical; Sensitivity and Specificity; Sputum; Tumor Cells, Cultured | 2015 |
Can a serum acetaminophen concentration obtained less than 4 hours post-ingestion determine which patients do not require treatment with acetylcysteine?
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Analgesics, Non-Narcotic; Antidotes; Female; Humans; Male; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Time Factors; Young Adult | 2017 |
Quantification of sulforaphane mercapturic acid pathway conjugates in human urine by high-performance liquid chromatography and isotope-dilution tandem mass spectrometry.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Humans; Indicator Dilution Techniques; Isotopes; Sensitivity and Specificity; Tandem Mass Spectrometry; Urine | 2008 |
Rapid and sensitive HILIC-ESI-MS/MS quantitation of polar metabolites of acrylamide in human urine using column switching with an online trap column.
Topics: Acetylcysteine; Acrylamide; Adult; Chromatography, Liquid; Female; Humans; Male; Sensitivity and Specificity; Tandem Mass Spectrometry; Young Adult | 2008 |
N-Acetyl-S-(1-carbamoyl-2-hydroxy-ethyl)-L-cysteine (iso-GAMA) a further product of human metabolism of acrylamide: comparison with the simultaneously excreted other mercaptuic acids.
Topics: Acetylcysteine; Acrylamide; Carcinogens; Cysteine; Epoxy Compounds; Humans; Kinetics; Male; Molecular Structure; Oxidation-Reduction; Sensitivity and Specificity | 2009 |
Quantitative determination of the 1,3-butadiene urinary metabolite 1,2-dihydroxybutyl mercapturic acid by high-performance liquid chromatography/tandem mass spectrometry using polynomial calibration curves.
Topics: Acetylcysteine; Butadienes; Calibration; Chromatography, High Pressure Liquid; Humans; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Uncertainty | 2009 |
Regulation of renin gene expression by oxidative stress.
Topics: Acetylcysteine; Analysis of Variance; Cells, Cultured; Gene Expression Regulation; Humans; Luciferases; Microarray Analysis; Oxidative Stress; Probability; Reactive Oxygen Species; Renin; RNA; Sensitivity and Specificity; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2009 |
An improved HPLC method for the investigation of L-selenomethionine metabolism in rat gut contents.
Topics: Acetylcysteine; Animals; Benzenesulfonates; Chromatography, High Pressure Liquid; Gastrointestinal Contents; Male; o-Phthalaldehyde; Rats; Rats, Wistar; Reproducibility of Results; Salicylates; Selenomethionine; Sensitivity and Specificity | 2009 |
Near-infrared luminescence quenching method for the detection of phenolic compounds using N-acetyl-L-cysteine-protected gold nanoparticles-tyrosinase hybrid material.
Topics: Acetylcysteine; Biosensing Techniques; Equipment Design; Equipment Failure Analysis; Gold; Luminescent Measurements; Monophenol Monooxygenase; Nanoparticles; Nanotechnology; Phenols; Reproducibility of Results; Sensitivity and Specificity; Spectroscopy, Near-Infrared | 2010 |
Accurate quantification of mercapturic acids of styrene (PHEMAs) in human urine with direct sample injection using automated column-switching high-performance liquid chromatography coupled with tandem mass spectrometry.
Topics: Acetylcysteine; Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Occupational Exposure; Sensitivity and Specificity; Styrene; Tandem Mass Spectrometry | 2010 |
[Determination of S-phenylmercapturic acid in human urine by HPLC-MS].
Topics: Acetylcysteine; Benzene; Biomarkers; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Mass Spectrometry; Occupational Exposure; Sensitivity and Specificity | 2010 |
Measurement of S-methylcysteine and S-methyl-mercapturic acid in human urine by alkyl-chloroformate extractive derivatization and isotope-dilution gas chromatography-mass spectrometry.
Topics: Acetylcysteine; Adult; Biomarkers; Calibration; Cysteine; Female; Formates; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Male; Methylhistidines; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Liquid chromatography tandem mass spectrometry method for determination of N-acetylcysteine in human plasma using an isotope-labeled internal standard.
Topics: Acetylcysteine; Chromatography, Liquid; Drug Stability; Humans; Linear Models; Male; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Therapeutic Equivalency; Trichloroacetic Acid | 2011 |
A quantitative approach to evaluate urinary benzene and S-phenylmercapturic acid as biomarkers of low benzene exposure.
Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Benzene; Biomarkers; Case-Control Studies; Cotinine; Environmental Monitoring; Female; Humans; Male; Methods; Middle Aged; Occupational Exposure; Sensitivity and Specificity | 2011 |
Direct agglutination test (DAT): improvement of biosafety for laboratory diagnosis of visceral leishmaniasis.
Topics: Acetylcysteine; Agglutination Tests; Clinical Laboratory Techniques; Humans; Kaolin; Leishmania infantum; Leishmaniasis, Visceral; Mercaptoethanol; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans.
Topics: Acetylcysteine; Butadienes; Carcinogens; Chromatography, High Pressure Liquid; Humans; Sensitivity and Specificity; Smoking; Smoking Cessation; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2011 |
Evaluation of a simple loop-mediated isothermal amplification test kit for the diagnosis of tuberculosis.
Topics: Acetylcysteine; Developing Countries; DNA, Bacterial; Humans; Mycobacterium tuberculosis; Nucleic Acid Amplification Techniques; Sensitivity and Specificity; Sodium Hydroxide; Sputum; Tuberculosis | 2011 |
Correlation of MRI findings to histology of acetaminophen toxicity in the mouse.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antidotes; Expectorants; Liver Failure, Acute; Magnetic Resonance Imaging; Male; Mice; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Treatment Outcome | 2012 |
Simultaneous quantitation of urinary cotinine and acrylonitrile-derived mercapturic acids with ultraperformance liquid chromatography-tandem mass spectrometry.
Topics: Acetylcysteine; Acrylonitrile; Carcinogens; Chromatography, High Pressure Liquid; Cotinine; Humans; Sensitivity and Specificity; Smoking; Tandem Mass Spectrometry | 2012 |
A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-L-cysteine assay.
Topics: Acetylcysteine; Enzyme Assays; Lactoylglutathione Lyase; Phenylhydrazines; Pyruvaldehyde; Saccharomyces cerevisiae; Sensitivity and Specificity; Spectrophotometry; Time Factors | 2012 |
Layer-by-layer immobilization of carbon dots fluorescent nanomaterials on single optical fiber.
Topics: Acetylcysteine; Carbon; Cations, Divalent; Fluorescent Dyes; Mercury; Nanoparticles; Optical Fibers; Sensitivity and Specificity; Spectrometry, Fluorescence | 2012 |
Comparison of C(18)-carboxypropylbetaine and standard N-acetyl-L-cysteine-NaOH processing of respiratory specimens for increasing tuberculosis smear sensitivity in Brazil.
Topics: Acetylcysteine; Bacteriological Techniques; Betaine; Brazil; Culture Media; Humans; Mycobacterium tuberculosis; Sensitivity and Specificity; Sodium Hydroxide; Specimen Handling; Sputum; Staining and Labeling; Tuberculosis, Pulmonary | 2002 |
Personal exposure to different levels of benzene and its relationships to the urinary metabolites S-phenylmercapturic acid and trans,trans-muconic acid.
Topics: Acetylcysteine; Animals; Benzene; Carbon Isotopes; China; Demography; Female; Humans; Male; Occupational Exposure; Rats; Rats, Inbred F344; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Sorbic Acid | 2002 |
Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats.
Topics: Acetylcysteine; Animals; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Mesylates; Molecular Structure; Naphthalenes; Naphthoquinones; Protein Binding; Rats; Rats, Inbred F344; Sensitivity and Specificity; Serum Albumin | 2002 |
A basic study of some normoxic polymer gel dosimeters.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Models, Chemical; Organophosphorus Compounds; Oxygen; Phantoms, Imaging; Phosphates; Polymers; Radiometry; Radiotherapy, Conformal; Sensitivity and Specificity; Time Factors | 2002 |
Simultaneous determination of metabolites of trimethylbenzenes, dimethylbenzylmercapturicacid and dimethylhippuric acid, in human urine by solid-phase extraction followed by liquid chromatography tandem mass spectrometry.
Topics: Acetylcysteine; Air Pollutants, Occupational; Chromatography, Liquid; Environmental Exposure; Hippurates; Humans; Molecular Structure; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Urinalysis; Xylenes | 2002 |
Spectroscopic characterization of the 4-hydroxy catechol estrogen quinones-derived GSH and N-acetylated Cys conjugates.
Topics: Acetylcysteine; Biomarkers, Tumor; Estrogens, Catechol; Glutathione; Luminescent Measurements; Models, Molecular; Quinones; Sensitivity and Specificity; Spectrometry, Fluorescence; Thermodynamics | 2003 |
Analysis of isothiocyanate mercapturic acids in urine: a biomarker for cruciferous vegetable intake.
Topics: Acetylcysteine; Biomarkers; Brassicaceae; Chromatography, High Pressure Liquid; Humans; Isothiocyanates; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Urinalysis; Urine | 2003 |
Determination of urinary S-phenylmercapturic acid by liquid chromatography-tandem mass spectrometry.
Topics: Acetylcysteine; Benzene; Calibration; Chromatography, High Pressure Liquid; Feasibility Studies; Humans; Occupational Exposure; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization | 2003 |
Determination of the major mercapturic acids of 1,3-butadiene in human and rat urine using liquid chromatography with tandem mass spectrometry.
Topics: Acetylcysteine; Adult; Animals; Calibration; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Benzene exposure measurement in shoe and glue manufacturing: a study to validate biomarkers.
Topics: Acetylcysteine; Adhesives; Benzene; Biomarkers; China; Humans; Industry; Occupational Exposure; Quality Control; Sensitivity and Specificity; Shoes; Toluene; Xylenes | 2003 |
The antioxidant N-acetylcysteine preserves myocardial function and diminishes oxidative stress after cardioplegic arrest.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiopulmonary Bypass; Disease Models, Animal; Dogs; Female; Heart Arrest, Induced; Heart Function Tests; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Oxidative Stress; Probability; Random Allocation; Reference Values; Risk Assessment; Sensitivity and Specificity; Ventricular Function, Left | 2003 |
Mechanisms of matrix metalloproteinase-9 and matrix metalloproteinase-2 inhibition by N-acetylcysteine in the human term decidua and fetal membranes.
Topics: Acetylcysteine; Adult; Blotting, Western; Case-Control Studies; Cesarean Section; Culture Techniques; Decidua; Extraembryonic Membranes; Female; Gestational Age; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pregnancy; Probability; Reference Values; Sampling Studies; Sensitivity and Specificity | 2003 |
Development of a wound dressing targeting neutrophil function.
Topics: Acetylcysteine; Bandages; Blood Bactericidal Activity; Cells, Cultured; Down-Regulation; Glutathione; Humans; Luminescent Measurements; Neutrophils; Nitric Oxide; Reactive Oxygen Species; Sensitivity and Specificity; Staphylococcus aureus; Tissue Engineering; Wound Healing; Wounds and Injuries | 2004 |
Development and validation of an isotope-dilution electrospray ionization tandem mass spectrometry method with an on-line sample clean-up device for the quantitative analysis of the benzene exposure biomarker S-phenylmercapturic acid in human urine.
Topics: Acetylcysteine; Adult; Benzene; Biomarkers; Environmental Exposure; Humans; Infant, Newborn; Online Systems; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Urinalysis | 2004 |
Significant statistical heterogeneity in a meta-analysis of the usefulness of acetylcysteine for prevention of contrast nephropathy.
Topics: Acetylcysteine; Acute Kidney Injury; Angiography; Contrast Media; Female; Humans; Incidence; Kidney; Kidney Function Tests; Male; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Statistics as Topic; Tomography, X-Ray Computed | 2004 |
An electrospray ionization tandem mass spectrometry based system with an online dual-loop cleanup device for simultaneous quantitation of urinary benzene exposure biomarkers trans,trans-muconic acid and S-phenylmercapturic acid.
Topics: Acetylcysteine; Benzene; Benzene Derivatives; Biomarkers; Computers; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Software; Sorbic Acid; Spectrometry, Mass, Electrospray Ionization | 2004 |
N-Acetylcysteine ameliorates lithium-induced renal failure in rats.
Topics: Acetylcysteine; Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Immunohistochemistry; Injections, Intraperitoneal; Kidney Function Tests; Lithium; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sensitivity and Specificity | 2005 |
Effect of N-acetylcysteine on antioxidant status in glycerol-induced acute renal failure in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Disease Models, Animal; Female; Glycerol; Kidney Function Tests; Male; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2004 |
Quantification of urinary N-acetyl-S- (propionamide)cysteine using an on-line clean-up system coupled with liquid chromatography/tandem mass spectrometry.
Topics: Acetylcysteine; Automation; Chromatography, Liquid; Electronic Data Processing; Health; Humans; Molecular Structure; Radioisotope Dilution Technique; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization | 2005 |
Liquid chromatography-multistage tandem mass spectrometry for the quantification of dihydroxynonene mercapturic acid (DHN-MA), a urinary end-metabolite of 4-hydroxynonenal.
Topics: Acetylcysteine; Aldehydes; Animals; Chromatography, Liquid; Deuterium; Linear Models; Male; Mass Spectrometry; Rats; Rats, Wistar; Sensitivity and Specificity | 2005 |
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.
Topics: Acetylcysteine; Biotin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Cystine; Electrochemistry; Electrodes; Glutathione; Gold; Homocysteine; Methionine; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Sulfur Compounds; Thioctic Acid | 2005 |
Determination of urinary S-phenylmercapturic acid, a specific metabolite of benzene, by liquid chromatography/single quadrupole mass spectrometry.
Topics: Acetylcysteine; Air Pollutants, Occupational; Benzene; Biomarkers; Calibration; Chromatography, Liquid; Humans; Mass Spectrometry; Sensitivity and Specificity | 2005 |
Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats.
Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Free Radicals; Glutathione; Hepatocytes; Lipid Peroxidation; Liver; Male; Models, Chemical; Oxidative Stress; Rats; Rats, Inbred F344; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2005 |
Utility of universal sample processing methodology, combining smear microscopy, culture, and PCR, for diagnosis of pulmonary tuberculosis.
Topics: Acetylcysteine; Bacteriological Techniques; Culture Media; DNA, Bacterial; Humans; Microscopy; Mycobacterium tuberculosis; Polymerase Chain Reaction; Sensitivity and Specificity; Sodium Hydroxide; Specimen Handling; Sputum; Staining and Labeling; Tuberculosis, Pulmonary | 2005 |
Monitoring low benzene exposure: comparative evaluation of urinary biomarkers, influence of cigarette smoking, and genetic polymorphisms.
Topics: Acetylcysteine; Adult; Benzene; Carcinogens; Case-Control Studies; Female; Humans; Male; Middle Aged; Occupational Exposure; Polymorphism, Genetic; Reference Values; Risk Assessment; Sensitivity and Specificity; Smoking; Sorbic Acid; Transportation | 2005 |
Rapid detection and identification of N-acetyl-L-cysteine thioethers using constant neutral loss and theoretical multiple reaction monitoring combined with enhanced product-ion scans on a linear ion trap mass spectrometer.
Topics: Acetylcysteine; Algorithms; Animals; Chromatography, High Pressure Liquid; Computer Simulation; Computer Systems; Models, Chemical; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfides; Xenobiotics | 2005 |
Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations.
Topics: Acetylcysteine; Biosensing Techniques; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Fluorescence Resonance Energy Transfer; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Pertussis Toxin; Receptors, Calcium-Sensing; Sensitivity and Specificity; Signal Transduction | 2005 |
N-acetylcysteine increases manganese superoxide dismutase activity in septic rat diaphragms.
Topics: Acetylcysteine; Analysis of Variance; Animals; Biopsy, Needle; Diaphragm; Disease Models, Animal; Immunohistochemistry; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Sepsis; Superoxide Dismutase | 2005 |
Enzyme immunoassay for a urinary metabolite of 4-hydroxynonenal as a marker of lipid peroxidation.
Topics: Acetylcysteine; Aldehydes; Alkenes; Animals; Biomarkers; Bromotrichloromethane; Chromatography, Liquid; Cross Reactions; Free Radicals; Immunoenzyme Techniques; Lipid Peroxidation; Male; Rabbits; Rats; Rats, Wistar; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trinitrobenzenesulfonic Acid | 2006 |
Non-destructive micromethod for MRP1 functional assay in human lung tumor cells.
Topics: Acetylcysteine; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Buthionine Sulfoximine; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Fluorometry; Glutathione; Humans; Immunohistochemistry; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Sensitivity and Specificity; Verapamil | 2006 |
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arginine; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Copper; Dietary Supplements; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Human T-lymphotropic virus 1; Humans; Lysine; Manganese; Proline; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sensitivity and Specificity; Structure-Activity Relationship; T-Lymphocytes; Transforming Growth Factors | 2006 |
Effects of N-acetylcysteine on radiocontrast nephropathy in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney Function Tests; Kidney Tubules; Probability; Radiopharmaceuticals; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Factors; Sensitivity and Specificity | 2006 |
Antioxidant therapy with N-acetylcysteine plus mesalamine accelerates mucosal healing in a rodent model of colitis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biopsy, Needle; Colitis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Immunohistochemistry; Inflammation Mediators; Male; Mesalamine; Peroxidase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2006 |
Adsorption kinetics, orientation, and self-assembling of N-acetyl-L-cysteine on gold: a combined ATR-IR, PM-IRRAS, and QCM study.
Topics: Acetylcysteine; Adsorption; Carboxylic Acids; Gold; Kinetics; Membranes, Artificial; Models, Chemical; Quartz; Sensitivity and Specificity; Spectrophotometry, Infrared; Surface Properties; Time Factors | 2005 |
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.
Topics: Acetylcysteine; Dimethyl Fumarate; Esters; Fumarates; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Sensitivity and Specificity; Succinates; Time Factors | 2007 |
Tools in metabonomics: an integrated validation approach for LC-MS metabolic profiling of mercapturic acids in human urine.
Topics: Acetylcysteine; Adult; Chromatography, Liquid; Databases as Topic; Female; Humans; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Reference Values; Sensitivity and Specificity; Time Factors | 2007 |
N-acetylcysteine to ameliorate acute renal injury in a rat cardiopulmonary bypass model.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Cardiopulmonary Bypass; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Kidney Function Tests; Male; Oxidative Stress; Postoperative Complications; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sensitivity and Specificity | 2007 |
Determination of two mercapturic acids related to crotonaldehyde in human urine: influence of smoking.
Topics: Acetylcysteine; Adult; Aged; Alcohol Drinking; Aldehydes; Biomarkers; Calibration; Chromatography, Liquid; Female; Humans; Male; Middle Aged; Reference Standards; Sensitivity and Specificity; Smoking; Tandem Mass Spectrometry | 2007 |
Fast determination of urinary S-phenylmercapturic acid (S-PMA) and S-benzylmercapturic acid (S-BMA) by column-switching liquid chromatography-tandem mass spectrometry.
Topics: Acetylcysteine; Adult; Automation; Biomarkers; Calibration; Chromatography, Liquid; Environmental Exposure; Environmental Monitoring; Female; Humans; Male; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Proteasome inhibitors in myocardial ischemia, some concerns.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Ischemic Preconditioning, Myocardial; Mice; Myocardial Ischemia; NF-kappa B; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reperfusion Injury; Risk Factors; Sensitivity and Specificity | 2008 |
Biological monitoring of exposure to benzene: a comparison between S-phenylmercapturic acid, trans,trans-muconic acid, and phenol.
Topics: Acetylcysteine; Air Pollutants, Occupational; Benzene; Environmental Monitoring; Half-Life; Humans; Male; Occupational Exposure; Phenols; Sensitivity and Specificity; Smoking; Sorbic Acid | 1995 |
Standardization of counting micronuclei: definition of a protocol to measure genotoxic damage in human exfoliated cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Cell Count; Cells, Cultured; Confidence Intervals; Gamma Rays; Head and Neck Neoplasms; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mouth Mucosa; Mouth Neoplasms; Mutagenicity Tests; Mutagens; Observer Variation; Patient Selection; Recurrence; Regression Analysis; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Vitamin A | 1995 |
Rendering of mycobacteria safe for molecular diagnostic studies and development of a lysis method for strand displacement amplification and PCR.
Topics: Acetylcysteine; Bacteriolysis; Base Sequence; Buffers; Containment of Biohazards; Disinfectants; DNA, Bacterial; Feasibility Studies; Hot Temperature; Humans; Molecular Sequence Data; Mycobacterium; Mycobacterium Infections; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Safety; Sensitivity and Specificity; Sodium Hydroxide; Time Factors | 1994 |
A nonradioactive assay for microsomal cysteine-S-conjugate N-acetyltransferase activity by high-pressure liquid chromatography.
Topics: Acetyl Coenzyme A; Acetylcysteine; Acetyltransferases; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; In Vitro Techniques; Kidney; Kinetics; Microsomes; Sensitivity and Specificity; Substrate Specificity; Swine | 1994 |
Determination of acrylamide metabolite, mercapturic acid by high performance liquid chromatography.
Topics: Acetylcysteine; Acrylamide; Acrylamides; Animals; Chromatography, High Pressure Liquid; Environmental Monitoring; Humans; Hydrolysis; Male; Occupational Exposure; Rats; Rats, Wistar; Sensitivity and Specificity | 1993 |
Application of the urinary S-phenylmercapturic acid test as a biomarker for low levels of exposure to benzene in industry.
Topics: Acetylcysteine; Air; Benzene; Biomarkers; Chemical Industry; Creatinine; Humans; Occupational Exposure; Sensitivity and Specificity; Time Factors | 1993 |
Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2-benzenedithiol.
Topics: Acetylcysteine; Carbon Disulfide; Chromatography, High Pressure Liquid; Disulfiram; Environmental Monitoring; Hydrogen-Ion Concentration; Isothiocyanates; Metals; Sensitivity and Specificity; Sulfhydryl Compounds; Thiocarbamates; Thiones; Thiourea; Thiram | 1996 |
Detection of human IgG antibodies against free N-acetyl-L-cysteine.
Topics: Acetylcysteine; Autoantibodies; HIV Seropositivity; Humans; Immunocompromised Host; Immunoconjugates; Immunoglobulin G; Nitric Oxide; Sensitivity and Specificity; Serum Albumin, Bovine; Tuberculosis | 1995 |
High-performance liquid chromatography assay for N-acetylcysteine in biological samples following derivatization with N-(1-pyrenyl)maleimide.
Topics: Acetylcysteine; Animals; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Free Radical Scavengers; Linear Models; Male; Maleimides; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sulfhydryl Reagents; Tissue Distribution | 1996 |
Sensitive gas chromatographic method for determination of mercapturic acids in human urine.
Topics: Acetylcysteine; Chromatography, Gas; Environmental Exposure; Humans; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Smoking | 1996 |
Synthesis and characterization of aflatoxin B1 mercapturic acids and their identification in rat urine.
Topics: Acetylcysteine; Aflatoxin B1; Animals; Biomarkers; Carcinogens; Circular Dichroism; Male; Mass Spectrometry; Rats; Rats, Inbred F344; Sensitivity and Specificity; Stereoisomerism | 1997 |
Determination of specific mercapturic acids as an index of exposure to environmental benzene, toluene, and styrene.
Topics: Acetylcysteine; Benzene; Biomarkers; Case-Control Studies; Humans; Linear Models; Occupational Exposure; Sensitivity and Specificity; Styrene; Styrenes; Toluene | 1997 |
Assay of S-ethyl-N-acetyl-l-cysteine in urine by high-performance liquid chromatography using post-column reaction detection.
Topics: Acetylation; Acetylcysteine; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Ethyl Chloride; Formates; Humans; Mercaptoethanol; Methanol; o-Phthalaldehyde; Sensitivity and Specificity; Solvents | 1997 |
N-methylcarbamoyl adducts at the N-terminal valine of globin in workers exposed to N,N-dimethylformamide.
Topics: Acetylcysteine; Case-Control Studies; Chemical Industry; Chromatography, Gas; Dimethylformamide; Globins; Heterocyclic Compounds; Humans; Male; Occupational Exposure; Sensitivity and Specificity; Solvents; Valine | 1998 |
High-performance liquid chromatographic analysis of vigabatrin enantiomers in human serum by precolumn derivatization with o-phthaldialdehyde-N-acetyl-L-cysteine and fluorescence detection.
Topics: Acetylcysteine; Adolescent; Adult; Anticonvulsants; Chromatography, High Pressure Liquid; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; Male; Middle Aged; o-Phthalaldehyde; Quality Control; Sensitivity and Specificity; Stereoisomerism; Vigabatrin | 1998 |
High-performance liquid chromatographic analysis of nitrite and nitrate in human plasma as S-nitroso-N-acetylcysteine with ultraviolet absorbance detection.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Humans; Nitrates; Nitrites; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1999 |
Determination of the urinary benzene metabolites S-phenylmercapturic acid and trans,trans-muconic acid by liquid chromatography-tandem mass spectrometry.
Topics: Acetylcysteine; Animals; Benzene; Biomarkers; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Environmental Exposure; Evaluation Studies as Topic; Humans; Mass Spectrometry; Rats; Rats, Inbred F344; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Smoking; Sorbic Acid; Urinalysis | 1999 |
Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins.
Topics: Acetylcysteine; Animals; Biomarkers; Biotransformation; DNA Damage; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Rats; Reference Standards; Sensitivity and Specificity; Tetrachloroethylene | 1999 |
Development of liquid chromatography-electrospray ionization-tandem mass spectrometry methods for determination of urinary metabolites of benzene in humans.
Topics: Acetylcysteine; Benzene; Biomarkers; Biotransformation; Carcinogens; Catechols; Chromatography, High Pressure Liquid; Humans; Hydroquinones; Mass Spectrometry; Sensitivity and Specificity; Smoking; Sorbic Acid; Urinalysis | 1999 |
Simultaneous determination of two human urinary metabolites of N,N-dimethylformamide using gas chromatography-thermionic sensitive detection with mass spectrometric confirmation.
Topics: Acetylcysteine; Dimethylformamide; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Linear Models; Occupational Exposure; Quality Control; Reference Values; Sensitivity and Specificity; Solvents | 1999 |
Determination of reduced and oxidized homocysteine and related thiols in plasma by thiol-specific pre-column derivatization and capillary electrophoresis with laser-induced fluorescence detection.
Topics: Acetylcysteine; Electrophoresis, Capillary; Glutathione; Homocysteine; Humans; Lasers; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
Validation of biomarkers in humans exposed to benzene: urine metabolites.
Topics: Acetylcysteine; Adhesives; Adult; Benzene; Biomarkers; Catechols; China; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydroquinones; Male; Mass Spectrometry; Mutagens; Occupational Exposure; Phenol; Reproducibility of Results; Sensitivity and Specificity; Shoes; Sorbic Acid | 2000 |
Biological monitoring of workers exposed to N,N-dimethylformamide in the synthetic fibre industry.
Topics: Acetylcysteine; Biomarkers; Chemical Industry; Chromatography, Gas; Dimethylformamide; Formamides; Humans; Male; Occupational Exposure; Sensitivity and Specificity | 2000 |
Proteasome inhibition measurements: clinical application.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cysteine Endopeptidases; Humans; In Vitro Techniques; Kinetics; Male; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2000 |
Lactacystin activates FLICE (caspase 8) protease and induces apoptosis in Fas-resistant adult T-cell leukemia cell lines.
Topics: Acetylcysteine; Adult; Anti-Bacterial Agents; Antigens, Surface; Apoptosis; Caspase 8; Caspase 9; Caspases; Cysteine Proteinase Inhibitors; Drug Resistance; Enzyme Activation; fas Receptor; Humans; Lactams; Leukemia, T-Cell; Sensitivity and Specificity; Tumor Cells, Cultured | 2000 |
A new method for the analysis of styrene mercapturic acids by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Acetylcysteine; Chromatography, Liquid; Environmental Pollutants; Epoxy Compounds; Glutathione; Glyoxylates; Humans; Mandelic Acids; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Styrene | 2000 |
Quantitation of catechol estrogens and their N-acetylcysteine conjugates in urine of rats and hamsters.
Topics: Acetylcysteine; Animals; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Cricetinae; Cross Reactions; Electrochemistry; Estradiol; Estrogens, Catechol; Female; Injections, Intraperitoneal; Male; Mesocricetus; Rabbits; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2000 |
High-performance liquid chromatographic-tandem mass spectrometric determination of 3-hydroxypropylmercapturic acid in human urine.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2001 |
Development of a class-selective enzyme-linked immunosorbent assay for mercapturic acids in human urine.
Topics: Acetylcysteine; Environmental Exposure; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Humans; Pesticide Residues; Sensitivity and Specificity | 2000 |
o-Phthalaldelhyde-N-acetylcysteine polyamine derivatives: formation and stability in solution and in C18 supports.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Drug Stability; o-Phthalaldehyde; Polyamines; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2001 |
Analysis of urinary N-acetyl-S-(N-methylcarbamoyl)cysteine, the mercapturic acid derived from N,N-dimethylformamide.
Topics: Acetylcysteine; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Dimethylformamide; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2001 |
Improving sensitivity of direct microscopy for detection of acid-fast bacilli in sputum: use of chitin in mucus digestion.
Topics: Acetylcysteine; Centrifugation; Chitin; Humans; Microbiological Techniques; Microscopy; Mycobacterium tuberculosis; Sensitivity and Specificity; Sodium Hypochlorite; Sputum; Tuberculosis | 2002 |
Increased proliferation of endothelial cells with overexpression of soluble TNF-alpha receptor I gene.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antigens, CD; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gene Expression; Genetic Vectors; Humans; Muscle, Smooth, Vascular; NF-kappa B; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins | 2002 |
Determination of intracellular glutathione and thiols by high performance liquid chromatography with a gold electrode at the femtomole level: comparison with a spectroscopic assay.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Electrochemistry; Electrodes; Glutathione; Gold; HL-60 Cells; Humans; Sensitivity and Specificity; Spectrophotometry; Sulfhydryl Compounds | 2002 |
Predictors of outcome after acetaminophen poisoning in children and adolescents.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Alanine Transaminase; Analgesics, Non-Narcotic; Arkansas; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Decision Making; Drug Overdose; Female; Free Radical Scavengers; Humans; Infant; Liver Diseases; Liver Function Tests; Male; Predictive Value of Tests; Prothrombin Time; Retrospective Studies; Sensitivity and Specificity | 2002 |