A valacyclovir hydrolase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q86WA6]
VACVase;
Valacyclovirase;
EC 3.1.-.-;
Biphenyl hydrolase-like protein;
Biphenyl hydrolase-related protein;
Bph-rp;
Breast epithelial mucin-associated antigen;
MCNAA
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| valacyclovir | Homo sapiens (human) | Km | 68.0000 | 1 | 1 |
This protein enables 1 target(s):
| Target | Category | Definition |
|---|---|---|
| alpha-amino-acid esterase activity | molecular function | Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol. [EC:3.1.1.43, MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN] |
This protein is located in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| mitochondrion | cellular component | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732] |
| mitochondrial outer membrane | cellular component | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. [GOC:ai] |
This protein is involved in 3 target(s):
| Target | Category | Definition |
|---|---|---|
| amino acid metabolic process | biological process | The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. [ISBN:0198506732] |
| xenobiotic metabolic process | biological process | The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc] |
| response to toxic substance | biological process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. [GOC:lr] |