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Carbonic anhydrase
[no definition available]
Synonyms
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (51)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| acetazolamide | Astrosclera willeyana | Ki | 0.0510 | 2 | 2 |
| celecoxib | Astrosclera willeyana | Ki | 0.7320 | 1 | 1 |
| dichlorphenamide | Astrosclera willeyana | Ki | 0.0620 | 1 | 1 |
| ethoxzolamide | Astrosclera willeyana | Ki | 0.3870 | 1 | 1 |
| hydrochlorothiazide | Astrosclera willeyana | Ki | 0.3940 | 1 | 1 |
| mafenide | Astrosclera willeyana | Ki | 0.9730 | 1 | 1 |
| methazolamide | Astrosclera willeyana | Ki | 0.3260 | 1 | 1 |
| saccharin | Astrosclera willeyana | Ki | 0.7510 | 1 | 1 |
| sodium fluoride | Astrosclera willeyana | Ki | 940.0000 | 1 | 1 |
| sodium iodide | Astrosclera willeyana | Ki | 10,400.0000 | 1 | 1 |
| sulfanilamide | Astrosclera willeyana | Ki | 7.7000 | 1 | 1 |
| sulpiride | Astrosclera willeyana | Ki | 0.3780 | 1 | 1 |
| sulthiame | Astrosclera willeyana | Ki | 0.2760 | 1 | 1 |
| zonisamide | Astrosclera willeyana | Ki | 0.1650 | 1 | 1 |
| 4-toluenesulfonamide | Astrosclera willeyana | Ki | 0.6750 | 1 | 1 |
| benzenearsonic acid | Astrosclera willeyana | Ki | 72.0000 | 1 | 1 |
| carzenide | Astrosclera willeyana | Ki | 1.2150 | 1 | 1 |
| sodium cyanide | Astrosclera willeyana | Ki | 630.0000 | 1 | 1 |
| sodium carbonate | Astrosclera willeyana | Ki | 13,500.0000 | 1 | 1 |
| benzolamide | Astrosclera willeyana | Ki | 0.0320 | 1 | 1 |
| sodium nitrate | Astrosclera willeyana | Ki | 76,400.0000 | 1 | 1 |
| sodium pyrophosphate | Astrosclera willeyana | Ki | 57,700.0000 | 1 | 1 |
| sodium sulfate | Astrosclera willeyana | Ki | 76,300.0000 | 1 | 1 |
| sodium selenate | Astrosclera willeyana | Ki | 880.0000 | 1 | 1 |
| sodium bisulfide | Astrosclera willeyana | Ki | 490.0000 | 1 | 1 |
| sodium azide | Astrosclera willeyana | Ki | 27,800.0000 | 1 | 1 |
| sodium persulfate | Astrosclera willeyana | Ki | 70,600.0000 | 1 | 1 |
| benzeneboronic acid | Astrosclera willeyana | Ki | 9.6000 | 1 | 1 |
| 4-amino-6-chloro-1,3-benzenedisulfonamide | Astrosclera willeyana | Ki | 0.8200 | 1 | 1 |
| brinzolamide | Astrosclera willeyana | Ki | 0.2780 | 1 | 1 |
| 2,4-disulfamyl-5-trifluoromethylaniline | Astrosclera willeyana | Ki | 0.5520 | 1 | 1 |
| 2-aminobenzenesulfonamide | Astrosclera willeyana | Ki | 7.7500 | 1 | 1 |
| sulfamide | Astrosclera willeyana | Ki | 8.9000 | 1 | 1 |
| 5-amino-1,3,4-thiadiazole-2-sulfonamide | Astrosclera willeyana | Ki | 0.3700 | 1 | 1 |
| valdecoxib | Astrosclera willeyana | Ki | 0.5170 | 1 | 1 |
| chlorzolamide | Astrosclera willeyana | Ki | 0.7920 | 1 | 1 |
| 4-(2-aminoethyl)benzenesulfonamide | Astrosclera willeyana | Ki | 0.7150 | 1 | 1 |
| n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | Astrosclera willeyana | Ki | 0.4230 | 1 | 1 |
| sodium bromide | Astrosclera willeyana | Ki | 30,600.0000 | 1 | 1 |
| sodium thiocyanate | Astrosclera willeyana | Ki | 670.0000 | 1 | 1 |
| sodium bicarbonate | Astrosclera willeyana | Ki | 22,800.0000 | 1 | 1 |
| sodium cyanate | Astrosclera willeyana | Ki | 230.0000 | 1 | 1 |
| sodium perchlorate | Astrosclera willeyana | Ki | 5,110.0000 | 1 | 1 |
| ditiocarb sodium | Astrosclera willeyana | Ki | 450.0000 | 1 | 1 |
| 2,6-dibromosulfanilamide | Astrosclera willeyana | Ki | 0.9650 | 1 | 1 |
| dorzolamide | Astrosclera willeyana | Ki | 0.2800 | 1 | 1 |
| topiramate | Astrosclera willeyana | Ki | 0.0380 | 1 | 1 |
| 6-hydroxybenzothiazide-2-sulfonamide | Astrosclera willeyana | Ki | 0.8660 | 1 | 1 |
| sodium bisulfate | Astrosclera willeyana | Ki | 88,100.0000 | 1 | 1 |
| sodium bisulfite | Astrosclera willeyana | Ki | 320.0000 | 1 | 1 |
| sodium nitrite | Astrosclera willeyana | Ki | 63,800.0000 | 1 | 1 |
Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 22, Issue:3, 2012
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.Bioorganic & medicinal chemistry, , Feb-15, Volume: 20, Issue:4, 2012