Proteins > Glycogen phosphorylase, muscle form
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Glycogen phosphorylase, muscle form
A glycogen phosphorylase, muscle form that is encoded in the genome of rabbit. [OMA:P00489, PRO:DNx]
Synonyms
EC 2.4.1.1;
Myophosphorylase
Research
Bioassay Publications (30)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 20 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (38)
Drugs with Inhibition Measurements
2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.European journal of medicinal chemistry, , Mar-23, Volume: 111, 2016
Synthesis, screening and docking of small heterocycles as glycogen phosphorylase inhibitors.European journal of medicinal chemistry, , Sep-12, Volume: 84, 2014
Synthesis and evaluation of novel oleanolic acid derivatives as potential antidiabetic agents.Chemical biology & drug design, , Volume: 83, Issue:3, 2014
Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.Journal of medicinal chemistry, , Feb-09, Volume: 55, Issue:3, 2012
Design and synthesis of novel photoaffinity probes for study of the target proteins of oleanolic acid.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 22, Issue:2, 2012
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.Bioorganic & medicinal chemistry letters, , Jan-01, Volume: 21, Issue:1, 2011
Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.Journal of natural products, , Volume: 72, Issue:8, 2009
Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives.Bioorganic & medicinal chemistry, , Jul-01, Volume: 17, Issue:13, 2009
Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry letters, , Dec-15, Volume: 19, Issue:24, 2009
Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase.Journal of natural products, , Volume: 71, Issue:11, 2008
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry letters, , Jun-01, Volume: 16, Issue:11, 2006
Synthesis and evaluation of novel oleanolic acid derivatives as potential antidiabetic agents.Chemical biology & drug design, , Volume: 83, Issue:3, 2014
Design and synthesis of novel photoaffinity probes for study of the target proteins of oleanolic acid.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 22, Issue:2, 2012
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.Journal of natural products, , Volume: 72, Issue:8, 2009
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry letters, , Jun-01, Volume: 16, Issue:11, 2006
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.Journal of natural products, , Volume: 72, Issue:8, 2009
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.Bioorganic & medicinal chemistry letters, , Jan-01, Volume: 21, Issue:1, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase.Journal of natural products, , Volume: 71, Issue:11, 2008
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.European journal of medicinal chemistry, , Nov-10, Volume: 123, 2016
1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.Bioorganic & medicinal chemistry, , May-15, Volume: 18, Issue:10, 2010
Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , Oct-15, Volume: 17, Issue:20, 2009
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , 11-01, Volume: 24, Issue:21, 2016
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.Bioorganic & medicinal chemistry, , Sep-01, Volume: 22, Issue:17, 2014
Synthesis, enzyme kinetics and computational evaluation of N-(β-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , Sep-15, Volume: 21, Issue:18, 2013
N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.Bioorganic & medicinal chemistry, , Mar-01, Volume: 20, Issue:5, 2012
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry, , Jul-01, Volume: 17, Issue:13, 2009
Novel design principle validated: glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent.Bioorganic & medicinal chemistry letters, , Oct-15, Volume: 18, Issue:20, 2008
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.Bioorganic & medicinal chemistry, , Sep-01, Volume: 22, Issue:17, 2014
N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.Bioorganic & medicinal chemistry, , Mar-01, Volume: 20, Issue:5, 2012
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry, , Jul-01, Volume: 17, Issue:13, 2009
Novel design principle validated: glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent.Bioorganic & medicinal chemistry letters, , Oct-15, Volume: 18, Issue:20, 2008
Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.Journal of medicinal chemistry, , 11-22, Volume: 60, Issue:22, 2017
Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.European journal of medicinal chemistry, , Nov-10, Volume: 123, 2016
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , 11-01, Volume: 24, Issue:21, 2016
4(5)-Aryl-2-C-glucopyranosyl-imidazoles as New Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase.ACS medicinal chemistry letters, , Dec-10, Volume: 6, Issue:12, 2015
New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase.European journal of medicinal chemistry, , Apr-09, Volume: 76, 2014
C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.ACS medicinal chemistry letters, , Jul-11, Volume: 4, Issue:7, 2013
Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.Journal of medicinal chemistry, , Feb-09, Volume: 55, Issue:3, 2012
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry, , Jul-01, Volume: 17, Issue:13, 2009
Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.European journal of medicinal chemistry, , Nov-10, Volume: 123, 2016
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , 11-01, Volume: 24, Issue:21, 2016
4(5)-Aryl-2-C-glucopyranosyl-imidazoles as New Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase.ACS medicinal chemistry letters, , Dec-10, Volume: 6, Issue:12, 2015
New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase.European journal of medicinal chemistry, , Apr-09, Volume: 76, 2014
C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.ACS medicinal chemistry letters, , Jul-11, Volume: 4, Issue:7, 2013
Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry, , Jul-01, Volume: 17, Issue:13, 2009
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.European journal of medicinal chemistry, , Jan-27, Volume: 108, 2016
N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.Bioorganic & medicinal chemistry, , Mar-01, Volume: 20, Issue:5, 2012
Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.Bioorganic & medicinal chemistry, , Oct-15, Volume: 17, Issue:20, 2009
Novel design principle validated: glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent.Bioorganic & medicinal chemistry letters, , Oct-15, Volume: 18, Issue:20, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase.Journal of natural products, , Volume: 71, Issue:11, 2008
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry letters, , Jun-01, Volume: 16, Issue:11, 2006
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.Bioorganic & medicinal chemistry letters, , Dec-15, Volume: 19, Issue:24, 2009
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.European journal of medicinal chemistry, , Volume: 46, Issue:6, 2011
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008