Page last updated: 2024-08-08 00:40:46

Solute carrier family 2, facilitated glucose transporter member 9

A solute carrier family 2, facilitated glucose transporter member 9 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NRM0]

Synonyms

Glucose transporter type 9;
GLUT-9;
Urate transporter

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (2)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
orotic acidHomo sapiens (human)IC501,000.000010
uric acidHomo sapiens (human)IC50300.000010

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
orotic acidHomo sapiens (human)EC501,000.000020
uric acidHomo sapiens (human)EC50300.000010

Enables

This protein enables 6 target(s):

TargetCategoryDefinition
carbohydrate:proton symporter activitymolecular functionEnables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in). [TC:2.A.1.1]
fructose transmembrane transporter activitymolecular functionEnables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
glucose transmembrane transporter activitymolecular functionEnables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
urate transmembrane transporter activitymolecular functionEnables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. [GOC:ai]
transmembrane transporter activitymolecular functionEnables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. [GOC:jid, GOC:mtg_transport, ISBN:0815340729]
hexose transmembrane transporter activitymolecular functionEnables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]

Located In

This protein is located in 4 target(s):

TargetCategoryDefinition
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
membranecellular componentA lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
basolateral plasma membranecellular componentThe region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators]
apical plasma membranecellular componentThe region of the plasma membrane located at the apical end of the cell. [GOC:curators]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

Involved In

This protein is involved in 7 target(s):

TargetCategoryDefinition
hexose transmembrane transportbiological processThe process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule. [GOC:vw]
urate transportbiological processThe directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]
fructose transmembrane transportbiological processThe directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. [GOC:ai]
urate metabolic processbiological processThe chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. [ISBN:0198506732]
proton transmembrane transportbiological processThe directed movement of a proton across a membrane. [GO_REF:0000069, GOC:pr, GOC:TermGenie]
glucose transmembrane transportbiological processThe process in which glucose is transported across a membrane. [GO_REF:0000069, GOC:TermGenie, PMID:9090050]
monosaccharide transmembrane transportbiological processThe process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. [GO_REF:0000069, GOC:TermGenie, GOC:vw]