Proteins > ATPase family AAA domain-containing protein 5
Page last updated: 2024-08-08 00:39:08

ATPase family AAA domain-containing protein 5

An ATPase family AAA domain-containing protein 5 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q96QE3]

Synonyms

Chromosome fragility-associated gene 1 protein

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (684)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
dinitrochlorobenzeneHomo sapiens (human)Potency24.584320
acetaldehydeHomo sapiens (human)Potency0.639410
adenineHomo sapiens (human)Potency18.833610
chlordeconeHomo sapiens (human)Potency62.904010
4-aminophenolHomo sapiens (human)Potency47.710920
hydroquinoneHomo sapiens (human)Potency54.150410
niacinamideHomo sapiens (human)Potency16.896610
pentachlorophenolHomo sapiens (human)Potency27.243110
phenylalanineHomo sapiens (human)Potency18.833610
pyrogallolHomo sapiens (human)Potency13.333210
selenious acidHomo sapiens (human)Potency0.426920
1,10-phenanthrolineHomo sapiens (human)Potency2.455910
4-(2,4-dichlorophenoxy)butyric acidHomo sapiens (human)Potency61.130610
2,4-dinitrophenolHomo sapiens (human)Potency5.698720
2-aminofluoreneHomo sapiens (human)Potency52.150020
3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octaneHomo sapiens (human)Potency28.226220
p-chloromercuribenzoic acidHomo sapiens (human)Potency54.482710
oxyquinolineHomo sapiens (human)Potency68.589610
acetochlorHomo sapiens (human)Potency28.932310
albendazoleHomo sapiens (human)Potency5.990720
alprazolamHomo sapiens (human)Potency16.834620
amlexanoxHomo sapiens (human)Potency5.123320
ampiroxicamHomo sapiens (human)Potency3.349120
anethole trithioneHomo sapiens (human)Potency33.491510
astemizoleHomo sapiens (human)Potency39.736720
azathioprineHomo sapiens (human)Potency3.833610
2,2-bis(4-glycidyloxyphenyl)propaneHomo sapiens (human)Potency71.556420
benzocaineHomo sapiens (human)Potency43.277110
benzyl isothiocyanateHomo sapiens (human)Potency69.287710
butylbenzyl phthalateHomo sapiens (human)Potency76.958810
bepridilHomo sapiens (human)Potency10.590910
beta-naphthoflavoneHomo sapiens (human)Potency0.069120
bithionolHomo sapiens (human)Potency6.591620
brotizolamHomo sapiens (human)Potency24.655820
butambenHomo sapiens (human)Potency19.531520
cannabinolHomo sapiens (human)Potency18.833610
carmofurHomo sapiens (human)Potency10.391520
carbonyl cyanide m-chlorophenyl hydrazoneHomo sapiens (human)Potency31.105820
celecoxibHomo sapiens (human)Potency54.261110
chlorambucilHomo sapiens (human)Potency61.852820
chloroxineHomo sapiens (human)Potency13.865020
chlorprophamHomo sapiens (human)Potency61.440020
cilostamideHomo sapiens (human)Potency15.358420
ciprofibrateHomo sapiens (human)Potency65.878410
cisplatinHomo sapiens (human)Potency26.603210
clenbuterolHomo sapiens (human)Potency2.304720
clioquinolHomo sapiens (human)Potency12.752710
clofoctolHomo sapiens (human)Potency26.603210
clotrimazoleHomo sapiens (human)Potency18.164310
dimethyl 2,3,5,6-tetrachloroterephthalateHomo sapiens (human)Potency68.589610
diazepamHomo sapiens (human)Potency33.171420
dichlorophenHomo sapiens (human)Potency10.590910
dichlorvosHomo sapiens (human)Potency26.603210
pentetic acidHomo sapiens (human)Potency26.603220
dilazepHomo sapiens (human)Potency9.110620
dimercaprolHomo sapiens (human)Potency14.960110
dipyridamoleHomo sapiens (human)Potency23.710110
dipyrithioneHomo sapiens (human)Potency2.822620
disulfiramHomo sapiens (human)Potency33.335820
valproic acidHomo sapiens (human)Potency68.589610
domperidoneHomo sapiens (human)Potency24.173920
endothallHomo sapiens (human)Potency43.342020
ethacrynic acidHomo sapiens (human)Potency68.101610
etizolamHomo sapiens (human)Potency26.603220
fenbendazoleHomo sapiens (human)Potency9.589020
fluorouracilHomo sapiens (human)Potency7.819320
fluspirileneHomo sapiens (human)Potency31.670420
flutamideHomo sapiens (human)Potency32.583020
liquid crystal polymerHomo sapiens (human)Potency27.139510
glutaralHomo sapiens (human)Potency59.684320
gossypolHomo sapiens (human)Potency36.870620
haloperidolHomo sapiens (human)Potency18.833610
hexachloropheneHomo sapiens (human)Potency1.760610
idebenoneHomo sapiens (human)Potency13.333210
indoprofenHomo sapiens (human)Potency0.595620
ipriflavoneHomo sapiens (human)Potency2.041720
leflunomideHomo sapiens (human)Potency3.902220
liranaftateHomo sapiens (human)Potency26.603210
loperamideHomo sapiens (human)Potency18.833610
loratadineHomo sapiens (human)Potency28.153810
mebendazoleHomo sapiens (human)Potency3.083120
methiothepinHomo sapiens (human)Potency33.491510
nocodazoleHomo sapiens (human)Potency3.643420
milrinoneHomo sapiens (human)Potency22.799010
nabumetoneHomo sapiens (human)Potency4.610520
naledHomo sapiens (human)Potency52.079420
nicardipineHomo sapiens (human)Potency31.108520
niclosamideHomo sapiens (human)Potency5.472810
nifedipineHomo sapiens (human)Potency24.008420
nilutamideHomo sapiens (human)Potency24.336510
nimetazepamHomo sapiens (human)Potency13.372220
nisoldipineHomo sapiens (human)Potency20.993420
osalmideHomo sapiens (human)Potency27.243520
oxatomideHomo sapiens (human)Potency21.131710
oxibendazoleHomo sapiens (human)Potency1.836720
phenacetinHomo sapiens (human)Potency61.130610
oxophenylarsineHomo sapiens (human)Potency0.077020
o-phthalaldehydeHomo sapiens (human)Potency9.807420
prazosinHomo sapiens (human)Potency33.491520
propachlorHomo sapiens (human)Potency15.969210
propentofyllineHomo sapiens (human)Potency23.710110
pyrimethamineHomo sapiens (human)Potency41.598010
raloxifeneHomo sapiens (human)Potency61.192710
riluzoleHomo sapiens (human)Potency12.235220
sanguinarineHomo sapiens (human)Potency13.333220
semustineHomo sapiens (human)Potency29.849310
vorinostatHomo sapiens (human)Potency1.993820
temazepamHomo sapiens (human)Potency26.603210
thiabendazoleHomo sapiens (human)Potency29.580020
thioridazineHomo sapiens (human)Potency30.433220
thiramHomo sapiens (human)Potency25.994920
tofisopamHomo sapiens (human)Potency24.655820
triamtereneHomo sapiens (human)Potency64.471820
triazolamHomo sapiens (human)Potency33.491510
triclosanHomo sapiens (human)Potency8.837310
octoxynolHomo sapiens (human)Potency13.333210
zardaverineHomo sapiens (human)Potency13.333220
zolpidemHomo sapiens (human)Potency13.333210
prednisoloneHomo sapiens (human)Potency0.015010
lysergic acid diethylamideHomo sapiens (human)Potency2.972910
norethindrone acetateHomo sapiens (human)Potency18.833610
spironolactoneHomo sapiens (human)Potency27.812420
methantheline bromideHomo sapiens (human)Potency11.883210
1,2,5,6-dibenzanthraceneHomo sapiens (human)Potency1.138020
2-acetylaminofluoreneHomo sapiens (human)Potency40.279220
idoxuridineHomo sapiens (human)Potency12.744810
methyldimethylaminoazobenzeneHomo sapiens (human)Potency1.539520
mechlorethamine hydrochlorideHomo sapiens (human)Potency22.558120
benz(a)anthraceneHomo sapiens (human)Potency53.684820
cetrimonium bromideHomo sapiens (human)Potency3.757810
vincristineHomo sapiens (human)Potency0.722120
9,10-dimethyl-1,2-benzanthraceneHomo sapiens (human)Potency61.187710
apomorphineHomo sapiens (human)Potency26.603210
methyltestosteroneHomo sapiens (human)Potency21.689910
promethazine hydrochlorideHomo sapiens (human)Potency62.960820
2,3,4,6-tetrachlorophenolHomo sapiens (human)Potency49.287210
bromodeoxyuridineHomo sapiens (human)Potency13.728220
p-aminoazobenzeneHomo sapiens (human)Potency15.222420
p-dimethylaminoazobenzeneHomo sapiens (human)Potency7.284820
methylene blueHomo sapiens (human)Potency14.960110
dimethylnitrosamineHomo sapiens (human)Potency60.819910
colchicineHomo sapiens (human)Potency0.135920
cycloheximideHomo sapiens (human)Potency0.317220
fluocinolone acetonideHomo sapiens (human)Potency0.008610
benziodaroneHomo sapiens (human)Potency26.603210
dinitrofluorobenzeneHomo sapiens (human)Potency26.025110
trypan blueHomo sapiens (human)Potency16.785510
chlorquinaldolHomo sapiens (human)Potency5.631920
carbon disulfideHomo sapiens (human)Potency42.749510
triamcinolone acetonideHomo sapiens (human)Potency0.072320
bromcresol greenHomo sapiens (human)Potency1.395920
hexachlorocyclopentadieneHomo sapiens (human)Potency25.969220
triparanolHomo sapiens (human)Potency29.849310
tris(2-butoxyethyl) phosphateHomo sapiens (human)Potency68.659410
tetrabromobisphenol aHomo sapiens (human)Potency57.850710
1,4-dihydroxyanthraquinoneHomo sapiens (human)Potency21.689910
1-amino-2-methylanthraquinoneHomo sapiens (human)Potency13.453420
acenaphthenequinoneHomo sapiens (human)Potency27.278310
quinophthaloneHomo sapiens (human)Potency0.082520
pindoneHomo sapiens (human)Potency3.935110
methylprednisoloneHomo sapiens (human)Potency0.034410
syrosingopineHomo sapiens (human)Potency9.932920
2-methylanthraquinoneHomo sapiens (human)Potency14.302820
santowhite powderHomo sapiens (human)Potency30.861920
2,2'-methylenebis(ethyl-6-tert-butylphenol)Homo sapiens (human)Potency27.840220
dinosebHomo sapiens (human)Potency1.269320
michler's ketoneHomo sapiens (human)Potency42.113020
3,3'-dichlorobenzidineHomo sapiens (human)Potency52.981620
4-phenylphenolHomo sapiens (human)Potency64.003620
benzidineHomo sapiens (human)Potency60.447420
4,4'-dihydroxybiphenylHomo sapiens (human)Potency57.001820
n,n-diethyl 4-phenylenediamineHomo sapiens (human)Potency15.777910
propylparabenHomo sapiens (human)Potency76.958810
isocaineHomo sapiens (human)Potency29.849310
benzylparabenHomo sapiens (human)Potency25.417420
butylparabenHomo sapiens (human)Potency47.932220
bis(1-piperidylthiocarbonyl)disulfideHomo sapiens (human)Potency29.849320
thiohexamHomo sapiens (human)Potency29.849310
1,2-diaminobenzeneHomo sapiens (human)Potency4.646320
2-methyl-1,4-hydroquinoneHomo sapiens (human)Potency65.586320
4-chloro-1,2-diaminobenzeneHomo sapiens (human)Potency39.018020
2-amino-4-methylphenolHomo sapiens (human)Potency68.659420
2,4,5-trichlorophenolHomo sapiens (human)Potency68.032010
4,4'-thiobis(6-tert-butyl-3-cresol)Homo sapiens (human)Potency36.882420
fentichlorHomo sapiens (human)Potency6.992320
o-aminoazotolueneHomo sapiens (human)Potency6.774120
tetramethylthiuram monosulfideHomo sapiens (human)Potency64.860120
p-tert-butyl catecholHomo sapiens (human)Potency64.053210
n,n-dimethylcyclohexylamineHomo sapiens (human)Potency76.255010
adrenaloneHomo sapiens (human)Potency42.163210
dimethyl-4-phenylenediamineHomo sapiens (human)Potency18.860320
4-nitroanilineHomo sapiens (human)Potency8.634910
4-nitrobenzyl chlorideHomo sapiens (human)Potency75.708310
phenylmercuric chlorideHomo sapiens (human)Potency10.074920
barbanHomo sapiens (human)Potency39.597820
n-isopropyl-n-phenyl-4-phenylenediamineHomo sapiens (human)Potency40.925910
diphenylguanidineHomo sapiens (human)Potency14.535220
monobenzoneHomo sapiens (human)Potency20.737720
citronellyl formateHomo sapiens (human)Potency61.130610
4-phenylenediamineHomo sapiens (human)Potency53.744020
diethanolamineHomo sapiens (human)Potency13.685410
bromphenol blueHomo sapiens (human)Potency12.538610
linalyl acetateHomo sapiens (human)Potency54.482710
2-aminoanthraquinoneHomo sapiens (human)Potency5.408620
dichloneHomo sapiens (human)Potency68.798910
2,2'-methylenebis(4-methyl-6-tert-butylphenol)Homo sapiens (human)Potency28.610420
dianisidineHomo sapiens (human)Potency53.584420
2-tolidineHomo sapiens (human)Potency71.532620
dibenzoylmethaneHomo sapiens (human)Potency11.680920
benzethonium chlorideHomo sapiens (human)Potency7.017620
sulfan blueHomo sapiens (human)Potency3.437610
deserpidineHomo sapiens (human)Potency3.349120
captanHomo sapiens (human)Potency42.373420
folpetHomo sapiens (human)Potency68.589610
phenyl 4-aminosalicylateHomo sapiens (human)Potency9.439220
2-Phenylethyl 2-aminobenzoateHomo sapiens (human)Potency0.919420
menthyl anthranilateHomo sapiens (human)Potency47.867210
neozoneHomo sapiens (human)Potency34.166620
1,3-diphenyl-1-triazeneHomo sapiens (human)Potency34.861220
phenazopyridine hydrochlorideHomo sapiens (human)Potency10.458020
4-nitrosodimethylanilineHomo sapiens (human)Potency45.495220
zephiramineHomo sapiens (human)Potency19.626410
4'-(chloroacetyl)acetanilideHomo sapiens (human)Potency24.336520
pentamidine isethionateHomo sapiens (human)Potency14.398220
4-tert-octylphenolHomo sapiens (human)Potency54.482710
sterogenolHomo sapiens (human)Potency8.934020
ethyl acetateHomo sapiens (human)Potency68.938510
benzo(e)pyreneHomo sapiens (human)Potency3.829610
benzo(b)fluorantheneHomo sapiens (human)Potency59.703510
chryseneHomo sapiens (human)Potency0.881320
ronnelHomo sapiens (human)Potency54.095110
hydralazine hydrochlorideHomo sapiens (human)Potency21.577020
disophenolHomo sapiens (human)Potency23.710110
evans blueHomo sapiens (human)Potency13.333210
azacitidineHomo sapiens (human)Potency3.947820
fluocinonideHomo sapiens (human)Potency0.004510
bucladesineHomo sapiens (human)Potency23.710110
cloflucarbanHomo sapiens (human)Potency8.412710
4-fluoroanilineHomo sapiens (human)Potency71.670010
triphenyltin fluorideHomo sapiens (human)Potency0.136910
cyproterone acetateHomo sapiens (human)Potency28.022010
emetineHomo sapiens (human)Potency0.334920
9-phenanthrolHomo sapiens (human)Potency13.487220
methyl redHomo sapiens (human)Potency49.726420
benzohydroxamic acidHomo sapiens (human)Potency73.295310
fenazoxHomo sapiens (human)Potency16.785510
3,4-toluenediamineHomo sapiens (human)Potency68.694320
chlorazanilHomo sapiens (human)Potency33.491520
chlorobenzilateHomo sapiens (human)Potency19.527910
dihydroergotamineHomo sapiens (human)Potency26.603210
podophyllotoxinHomo sapiens (human)Potency0.015520
dequalinium chlorideHomo sapiens (human)Potency2.266410
flavoneHomo sapiens (human)Potency19.629920
chrysoidineHomo sapiens (human)Potency2.347320
1,3-dichloroacetoneHomo sapiens (human)Potency22.344820
4,6-dinitro-o-cresolHomo sapiens (human)Potency10.953220
4,4'-diaminoazobenzeneHomo sapiens (human)Potency6.352320
domiphen bromideHomo sapiens (human)Potency29.038720
maleimideHomo sapiens (human)Potency78.998120
gentian violetHomo sapiens (human)Potency7.178720
amitriptyline hydrochlorideHomo sapiens (human)Potency68.589610
thallium acetateHomo sapiens (human)Potency8.687610
2-chloroacetanilideHomo sapiens (human)Potency54.482710
megestrol acetateHomo sapiens (human)Potency38.570810
2-bromopropionic acid, (dl)-isomerHomo sapiens (human)Potency76.958810
pentabromophenolHomo sapiens (human)Potency6.900810
2-anthramineHomo sapiens (human)Potency19.360820
4-EthoxyphenolHomo sapiens (human)Potency76.958810
dimethyl disulfideHomo sapiens (human)Potency69.427510
c.i. 42510Homo sapiens (human)Potency1.883410
brilliant greenHomo sapiens (human)Potency2.371020
Berberine chloride (TN)Homo sapiens (human)Potency1.946910
tridecanoic acidHomo sapiens (human)Potency48.705910
dibutyldichlorotinHomo sapiens (human)Potency0.332220
n-(1,3-dimethylbutyl)-n'-phenyl-1,4-phenylenediamineHomo sapiens (human)Potency67.405610
levonorgestrelHomo sapiens (human)Potency48.557710
tetrachloronitrobenzeneHomo sapiens (human)Potency68.310720
dodecylamineHomo sapiens (human)Potency65.582810
3-methoxycatecholHomo sapiens (human)Potency57.701820
n-phenylmaleimideHomo sapiens (human)Potency68.589610
dinobutonHomo sapiens (human)Potency21.689910
rhodamine 6gHomo sapiens (human)Potency0.072420
phenylglyoxalHomo sapiens (human)Potency68.659410
dichlofluanidHomo sapiens (human)Potency30.637910
dodecyltrimethylammonium bromideHomo sapiens (human)Potency4.327710
tetradecyltrimethylammonium bromideHomo sapiens (human)Potency12.096510
lauryl gallateHomo sapiens (human)Potency28.903810
1,8-octanedithiolHomo sapiens (human)Potency76.958810
furazabolHomo sapiens (human)Potency21.131710
ethidium bromideHomo sapiens (human)Potency18.709420
dinoterbHomo sapiens (human)Potency0.860910
flurandrenoloneHomo sapiens (human)Potency0.010110
bisphenol a-glycidyl methacrylateHomo sapiens (human)Potency17.228910
2,4-dinitrothiocyanatobenzeneHomo sapiens (human)Potency68.589610
4-hydroxyazobenzeneHomo sapiens (human)Potency12.711820
ioxynilHomo sapiens (human)Potency15.355310
bromoxynilHomo sapiens (human)Potency18.112910
bromoxynil octanoateHomo sapiens (human)Potency30.513310
2-amino-6-methoxybenzothiazoleHomo sapiens (human)Potency79.238820
tetrachloroisophthalonitrileHomo sapiens (human)Potency0.756920
tartrazineHomo sapiens (human)Potency0.118810
dronabinolHomo sapiens (human)Potency33.491510
pimozideHomo sapiens (human)Potency24.096320
bromophosHomo sapiens (human)Potency54.482710
flumethasoneHomo sapiens (human)Potency0.001410
phenethyl isothiocyanateHomo sapiens (human)Potency68.729110
ethoxazeneHomo sapiens (human)Potency0.202520
fast green fcfHomo sapiens (human)Potency16.579710
dexamethasone sodium phosphateHomo sapiens (human)Potency0.029810
2-tert-butyl-4-methylphenolHomo sapiens (human)Potency54.371910
captafolHomo sapiens (human)Potency6.138620
1,4-bis(2,3-epoxypropoxy)butaneHomo sapiens (human)Potency67.544710
drometrizoleHomo sapiens (human)Potency9.493620
1,3,5-triglycidyl-s-triazinetrioneHomo sapiens (human)Potency35.520220
azinphos ethylHomo sapiens (human)Potency27.306010
bromotriethylstannaneHomo sapiens (human)Potency3.063820
benzyl thiocyanateHomo sapiens (human)Potency77.272010
dichloroacetonitrileHomo sapiens (human)Potency74.928510
cyclohexylisocyanateHomo sapiens (human)Potency54.593510
dibromoacetonitrileHomo sapiens (human)Potency73.663920
dithianoneHomo sapiens (human)Potency24.336510
pentaerythrityl triacrylateHomo sapiens (human)Potency5.513320
n-butylbenzenesulfonamideHomo sapiens (human)Potency42.705610
chlorophacinoneHomo sapiens (human)Potency2.730610
2-(alpha-thenoylamino)-2-nitro-5-thiazoleHomo sapiens (human)Potency3.757820
Brilliant BlueHomo sapiens (human)Potency19.401710
flurazepam hydrochlorideHomo sapiens (human)Potency13.333210
fuberidazoleHomo sapiens (human)Potency29.356420
nitroxolineHomo sapiens (human)Potency4.216310
2,2',4'-trichloroacetophenoneHomo sapiens (human)Potency37.008320
cladribineHomo sapiens (human)Potency9.439210
fluoropheneHomo sapiens (human)Potency0.834610
carboxinHomo sapiens (human)Potency63.446620
1-nitropyreneHomo sapiens (human)Potency48.508420
methylene bis(thiocyanate)Homo sapiens (human)Potency29.195120
dimethyldodecylbenzylammoniumHomo sapiens (human)Potency10.274420
potassium dichromateHomo sapiens (human)Potency38.924110
phenmediphamHomo sapiens (human)Potency15.355310
hexadimethrine bromideHomo sapiens (human)Potency33.491510
antimony trichlorideHomo sapiens (human)Potency13.685410
sodium seleniteHomo sapiens (human)Potency13.143510
carbendazimHomo sapiens (human)Potency34.376210
1,6-hexanediol diacrylateHomo sapiens (human)Potency19.343220
pyrithione zincHomo sapiens (human)Potency1.320520
hydrocortisone-17-butyrateHomo sapiens (human)Potency0.037610
tris(1,3-dichloro-2-propyl)phosphateHomo sapiens (human)Potency68.241010
parbendazoleHomo sapiens (human)Potency0.853220
trimethylolpropane triacrylateHomo sapiens (human)Potency7.868320
2,3,4-trichlorophenolHomo sapiens (human)Potency63.375310
gestrinoneHomo sapiens (human)Potency13.421620
danazolHomo sapiens (human)Potency61.130610
tomatineHomo sapiens (human)Potency1.333310
deslanosideHomo sapiens (human)Potency0.326620
benomylHomo sapiens (human)Potency54.205810
tetraethylene glycol diacrylateHomo sapiens (human)Potency28.013620
methabenzthiazuronHomo sapiens (human)Potency62.326420
daunorubicinHomo sapiens (human)Potency0.443320
2-(thiocyanomethylthio)benzothiazoleHomo sapiens (human)Potency68.589620
2-bromoergocryptine mesylateHomo sapiens (human)Potency14.639310
bromocriptineHomo sapiens (human)Potency11.883220
fenitrothionHomo sapiens (human)Potency30.637910
cetalkonium chlorideHomo sapiens (human)Potency13.653920
dodecylbenzeneHomo sapiens (human)Potency68.659410
cetylpyridinium chloride anhydrousHomo sapiens (human)Potency6.859020
cetyldimethylethylammonium bromideHomo sapiens (human)Potency21.721020
tetramethylolphosphonium chlorideHomo sapiens (human)Potency61.130610
triamcinoloneHomo sapiens (human)Potency0.011910
tris(2,3-dibromopropyl)phosphateHomo sapiens (human)Potency51.356920
rafoxanideHomo sapiens (human)Potency33.491510
metipranololHomo sapiens (human)Potency29.849310
mono-benzyl phthalateHomo sapiens (human)Potency76.958810
cambendazoleHomo sapiens (human)Potency10.590920
frentizoleHomo sapiens (human)Potency0.829120
2-n-octyl-4-isothiazolin-3-oneHomo sapiens (human)Potency77.115410
lofepramine hydrochlorideHomo sapiens (human)Potency37.578010
penfluridolHomo sapiens (human)Potency31.063420
norflurazoneHomo sapiens (human)Potency52.570020
etoposideHomo sapiens (human)Potency8.412710
4-hexyloxyanilineHomo sapiens (human)Potency56.655820
ciclopirox olamineHomo sapiens (human)Potency14.299920
nicardipine hydrochlorideHomo sapiens (human)Potency34.166610
nitazoxanideHomo sapiens (human)Potency0.899120
closantelHomo sapiens (human)Potency26.603210
dinalineHomo sapiens (human)Potency9.302420
laurocapramHomo sapiens (human)Potency54.482710
midazolam hydrochlorideHomo sapiens (human)Potency26.603220
propiconazoleHomo sapiens (human)Potency55.481510
paroxetineHomo sapiens (human)Potency26.603210
flutolanilHomo sapiens (human)Potency24.336510
colforsinHomo sapiens (human)Potency0.230120
talniflumateHomo sapiens (human)Potency13.333210
triclabendazoleHomo sapiens (human)Potency18.833610
mitoxantrone hydrochlorideHomo sapiens (human)Potency3.137720
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanoneHomo sapiens (human)Potency42.805020
fanetizoleHomo sapiens (human)Potency3.482720
simvastatinHomo sapiens (human)Potency8.041410
benfuracarbHomo sapiens (human)Potency10.870710
raloxifene hydrochlorideHomo sapiens (human)Potency57.784720
ilmofosineHomo sapiens (human)Potency13.333210
mifepristoneHomo sapiens (human)Potency18.134820
mibefradil dihydrochlorideHomo sapiens (human)Potency10.904720
tenidapHomo sapiens (human)Potency21.131710
temoporfinHomo sapiens (human)Potency26.720920
fananserinHomo sapiens (human)Potency29.849310
monatepilHomo sapiens (human)Potency26.603210
duloxetine hydrochlorideHomo sapiens (human)Potency23.710110
aptiganel hydrochlorideHomo sapiens (human)Potency26.603210
ziprasidoneHomo sapiens (human)Potency26.603220
saquinavir monomethanesulfonateHomo sapiens (human)Potency43.868420
phenelzine sulfateHomo sapiens (human)Potency12.744810
1,2-dibromo-2,4-dicyanobutaneHomo sapiens (human)Potency68.589610
3-iodo-2-propynylbutylcarbamateHomo sapiens (human)Potency73.739220
benoxacorHomo sapiens (human)Potency15.957820
iberverinHomo sapiens (human)Potency57.806620
pentaerythritol tetraacrylateHomo sapiens (human)Potency6.356820
dioctyldimethyl ammonium chlorideHomo sapiens (human)Potency5.631920
daunorubicin hydrochlorideHomo sapiens (human)Potency0.286920
trovanHomo sapiens (human)Potency26.603210
sertraline hydrochlorideHomo sapiens (human)Potency33.491510
dexamethasone dipropionateHomo sapiens (human)Potency26.603210
efavirenzHomo sapiens (human)Potency29.849310
diphenylcyclopropenoneHomo sapiens (human)Potency37.578010
alpha-terthienylHomo sapiens (human)Potency31.237220
mefloquine hydrochlorideHomo sapiens (human)Potency28.810220
proadifen hydrochlorideHomo sapiens (human)Potency29.849310
triciribineHomo sapiens (human)Potency33.491510
narasinHomo sapiens (human)Potency0.188310
lauryloxypropylamineHomo sapiens (human)Potency33.491510
metrifudilHomo sapiens (human)Potency1.059110
pifexoleHomo sapiens (human)Potency7.547520
cgs 9343bHomo sapiens (human)Potency29.849310
azelnidipineHomo sapiens (human)Potency13.333220
4-nitrobenzyl bromideHomo sapiens (human)Potency53.787810
thioridazine hydrochlorideHomo sapiens (human)Potency62.072920
trifluoperazine hydrochlorideHomo sapiens (human)Potency26.950120
hexaconazoleHomo sapiens (human)Potency61.068410
moskeneHomo sapiens (human)Potency24.336510
4,4,4-trifluoro-1-phenyl-1,3-butanedioneHomo sapiens (human)Potency43.894010
6-methyladenineHomo sapiens (human)Potency50.587420
dyclonine hydrochlorideHomo sapiens (human)Potency5.692920
econazole nitrateHomo sapiens (human)Potency16.785510
artemisininHomo sapiens (human)Potency34.297720
drospirenoneHomo sapiens (human)Potency29.849310
quinocideHomo sapiens (human)Potency9.439220
ethyl 4-chloro-3-oxobutanoateHomo sapiens (human)Potency44.429420
2,6-di-tert-butyl-4-nitrophenolHomo sapiens (human)Potency1.087110
butanediol diacrylateHomo sapiens (human)Potency27.306020
2,3,4-trihydroxbenzophenoneHomo sapiens (human)Potency65.139310
amidonalHomo sapiens (human)Potency13.333220
maprotiline hydrochlorideHomo sapiens (human)Potency68.589610
mexenoneHomo sapiens (human)Potency33.491510
tioxidazoleHomo sapiens (human)Potency1.998320
tosyllysine chloromethyl ketoneHomo sapiens (human)Potency33.491520
gramicidin sHomo sapiens (human)Potency0.154020
clofentezineHomo sapiens (human)Potency45.039820
perfluorooctane sulfonic acidHomo sapiens (human)Potency1.535510
victoria blue boHomo sapiens (human)Potency0.085820
2-hydroxyfluoreneHomo sapiens (human)Potency61.130610
di-n-octyltin dichlorideHomo sapiens (human)Potency61.068410
isopropyl thioxanthoneHomo sapiens (human)Potency4.206720
tetraconazoleHomo sapiens (human)Potency62.373420
ethyl 2-cyanoacrylateHomo sapiens (human)Potency62.326420
bexaroteneHomo sapiens (human)Potency30.637910
flunisolideHomo sapiens (human)Potency4.006320
4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrileHomo sapiens (human)Potency43.277110
difenoconazoleHomo sapiens (human)Potency4.855810
metconazoleHomo sapiens (human)Potency61.130610
isoamyl 4-n,n-dimethylaminobenzoateHomo sapiens (human)Potency13.333220
bisphenol f diglycidyl etherHomo sapiens (human)Potency68.868720
acid green 50Homo sapiens (human)Potency14.960110
pencycuronHomo sapiens (human)Potency48.557710
penconazoleHomo sapiens (human)Potency43.277110
triflumizolHomo sapiens (human)Potency68.519910
ac 263,222Homo sapiens (human)Potency68.589610
chlorfenapyrHomo sapiens (human)Potency0.544810
riboflavin tetrabutyrateHomo sapiens (human)Potency23.710110
lopinavirHomo sapiens (human)Potency23.710110
tetrabromophenolphthalein ethyl esterHomo sapiens (human)Potency51.284910
alexidine dihydrchlorideHomo sapiens (human)Potency29.849320
vanoxerineHomo sapiens (human)Potency8.412710
ecteinascidin 743Homo sapiens (human)Potency0.243410
sm 9018Homo sapiens (human)Potency10.590910
clofarabineHomo sapiens (human)Potency0.530810
zoxamideHomo sapiens (human)Potency71.052820
lomerizine dihydrochlorideHomo sapiens (human)Potency12.908820
4'-demethylepipodophyllotoxinHomo sapiens (human)Potency1.781020
imatinib mesylateHomo sapiens (human)Potency11.883210
lestaurtinibHomo sapiens (human)Potency0.754720
methotrexateHomo sapiens (human)Potency0.133310
e 5880Homo sapiens (human)Potency21.131710
ilomastatHomo sapiens (human)Potency0.473110
febuxostatHomo sapiens (human)Potency0.158720
10-propargyl-10-deazaaminopterinHomo sapiens (human)Potency14.157220
docetaxel anhydrousHomo sapiens (human)Potency33.491510
nsc-141549Homo sapiens (human)Potency5.631920
centchromanHomo sapiens (human)Potency23.710110
canertinibHomo sapiens (human)Potency9.439210
cinacalcet hydrochlorideHomo sapiens (human)Potency29.287420
lercanidipine hydrochlorideHomo sapiens (human)Potency10.590910
cloperastine hydrochlorideHomo sapiens (human)Potency18.002510
fasudil hydrochlorideHomo sapiens (human)Potency18.833610
y 23023Homo sapiens (human)Potency27.601120
farglitazarHomo sapiens (human)Potency68.589610
abt 980Homo sapiens (human)Potency28.226220
mesotrioneHomo sapiens (human)Potency69.777110
bifenazateHomo sapiens (human)Potency63.691210
spirodiclofenHomo sapiens (human)Potency27.306010
deflazacortHomo sapiens (human)Potency24.507820
dronedaroneHomo sapiens (human)Potency33.491520
roxindoleHomo sapiens (human)Potency10.590910
demecolcineHomo sapiens (human)Potency0.237120
norethindrone enanthateHomo sapiens (human)Potency3.349110
epinastineHomo sapiens (human)Potency0.005110
niguldipine hydrochlorideHomo sapiens (human)Potency11.176620
o-(chloroacetylcarbamoyl)fumagillolHomo sapiens (human)Potency18.782410
bortezomibHomo sapiens (human)Potency0.020420
ritonavirHomo sapiens (human)Potency9.439210
bardoxolone methylHomo sapiens (human)Potency3.349120
nexavarHomo sapiens (human)Potency4.299620
methylmercuric chlorideHomo sapiens (human)Potency5.973320
ouabainHomo sapiens (human)Potency1.741520
griseofulvinHomo sapiens (human)Potency26.805220
digitoxinHomo sapiens (human)Potency1.916620
nortriptyline hydrochlorideHomo sapiens (human)Potency33.491510
securinineHomo sapiens (human)Potency6.682420
acriflavineHomo sapiens (human)Potency33.491510
devazepideHomo sapiens (human)Potency12.115620
calcium pantothenateHomo sapiens (human)Potency8.412710
carubicinHomo sapiens (human)Potency0.942420
doxorubicin hydrochlorideHomo sapiens (human)Potency0.302020
medigoxinHomo sapiens (human)Potency0.075520
amcinonideHomo sapiens (human)Potency0.010610
tretinoinHomo sapiens (human)Potency31.144820
resveratrolHomo sapiens (human)Potency2.975120
tacrolimusHomo sapiens (human)Potency16.785510
mycophenolic acidHomo sapiens (human)Potency9.022610
afimoxifeneHomo sapiens (human)Potency77.113920
decitabineHomo sapiens (human)Potency1.188310
valrubicinHomo sapiens (human)Potency3.286120
ketoconazoleHomo sapiens (human)Potency16.508320
diclazurilHomo sapiens (human)Potency13.333210
dactinomycinHomo sapiens (human)Potency0.149310
melphalanHomo sapiens (human)Potency30.433220
posaconazoleHomo sapiens (human)Potency5.308010
rubitecanHomo sapiens (human)Potency4.730810
idarubicin hydrochlorideHomo sapiens (human)Potency0.892620
fumaronitrileHomo sapiens (human)Potency60.521220
retinaldehydeHomo sapiens (human)Potency69.504820
piperineHomo sapiens (human)Potency11.823720
4-stilbazoleHomo sapiens (human)Potency21.978920
lanatoside cHomo sapiens (human)Potency0.086620
polidocanolHomo sapiens (human)Potency2.113210
prednisolone hemisuccinateHomo sapiens (human)Potency0.167910
(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanolHomo sapiens (human)Potency13.728220
mercaptopurineHomo sapiens (human)Potency2.371010
4,4'-sulfonylbis[2-(prop-2-en-1-yl)phenol]Homo sapiens (human)Potency61.130610
flunarizineHomo sapiens (human)Potency13.333210
thiothixeneHomo sapiens (human)Potency33.491510
curcuminHomo sapiens (human)Potency48.369620
tenovin-1Homo sapiens (human)Potency1.333310
n-(fluorenyl-9-methoxycarbonyl)leucineHomo sapiens (human)Potency14.388820
1-phenyl-2-nitropropeneHomo sapiens (human)Potency31.860020
3-(4-methoxyphenyl)-2-propenoic acid 3-methylbutyl esterHomo sapiens (human)Potency26.603210
cyqualonHomo sapiens (human)Potency33.491510
indigo carmineHomo sapiens (human)Potency34.376210
digoxinHomo sapiens (human)Potency1.531820
malachite greenHomo sapiens (human)Potency0.650420
quinacrine monohydrochlorideHomo sapiens (human)Potency29.849320
tamoxifen citrateHomo sapiens (human)Potency50.230420
tamoxifenHomo sapiens (human)Potency61.317210
tetraoctylammonium bromideHomo sapiens (human)Potency0.364020
1-methyl-3-octylimidazolium chlorideHomo sapiens (human)Potency8.573510
1-hexadecyl-3-methylimidazolium chlorideHomo sapiens (human)Potency6.422320
1-octyl-3-methylimidazolium hexafluorophosphateHomo sapiens (human)Potency14.376220
2,4-dithiobiuretHomo sapiens (human)Potency43.277110
zeranolHomo sapiens (human)Potency40.737010
timiperoneHomo sapiens (human)Potency23.710110
tandutinibHomo sapiens (human)Potency33.491510
trequinsin hydrochlorideHomo sapiens (human)Potency27.123620
dasatinibHomo sapiens (human)Potency17.809620
emetine dihydrochlorideHomo sapiens (human)Potency0.316120
1,8-dinitro-4,5-dihydroxyanthraquinoneHomo sapiens (human)Potency1.032120
tripropylene glycol diacrylateHomo sapiens (human)Potency34.653420
tolcaponeHomo sapiens (human)Potency19.051120
diethyl maleateHomo sapiens (human)Potency76.958810
benzyl cinnamateHomo sapiens (human)Potency6.859010
5,6-dehydrokawainHomo sapiens (human)Potency8.756820
biochanin aHomo sapiens (human)Potency3.001520
formononetinHomo sapiens (human)Potency2.125920
apigeninHomo sapiens (human)Potency5.448220
zeaxanthinHomo sapiens (human)Potency28.810220
genisteinHomo sapiens (human)Potency8.163920
pulmicortHomo sapiens (human)Potency0.006010
prochlorperazine maleateHomo sapiens (human)Potency31.039920
entacaponeHomo sapiens (human)Potency33.491510
yangoninHomo sapiens (human)Potency20.992020
zearalenoneHomo sapiens (human)Potency16.593510
coumestrolHomo sapiens (human)Potency62.165220
daidzeinHomo sapiens (human)Potency33.534020
hydramethylnonHomo sapiens (human)Potency76.958820
flupenthixolHomo sapiens (human)Potency33.491510
cilnidipineHomo sapiens (human)Potency26.603210
gamma-oryzanolHomo sapiens (human)Potency18.965520
uf 021Homo sapiens (human)Potency25.092720
pelubiprofenHomo sapiens (human)Potency16.785510
tranilastHomo sapiens (human)Potency1.066120
misoprostolHomo sapiens (human)Potency5.308010
2,4-decadienalHomo sapiens (human)Potency68.032010
di-allateHomo sapiens (human)Potency34.586110
perhexiline maleateHomo sapiens (human)Potency29.849320
beta-nitrostyreneHomo sapiens (human)Potency25.089420
tetrachlorvinphosHomo sapiens (human)Potency10.870710
toxapheneHomo sapiens (human)Potency29.849310
zinc dibutyldithiocarbamateHomo sapiens (human)Potency13.775020
ethisteroneHomo sapiens (human)Potency54.482710
proscillaridinHomo sapiens (human)Potency0.013120
fenretinideHomo sapiens (human)Potency26.370420
desonideHomo sapiens (human)Potency0.011910
lacidipineHomo sapiens (human)Potency29.849310
vitamin b 12Homo sapiens (human)Potency12.744810
nifuroxazideHomo sapiens (human)Potency2.542910
bromebric acidHomo sapiens (human)Potency10.798120
alloocimeneHomo sapiens (human)Potency67.753420
2-Phenylethyl 3-phenyl-2-propenoateHomo sapiens (human)Potency28.972020
vinblastine sulfateHomo sapiens (human)Potency0.794520
parthenolideHomo sapiens (human)Potency28.226220
aztreonamHomo sapiens (human)Potency14.299910
indinavir sulfateHomo sapiens (human)Potency26.603220
quinaldine blueHomo sapiens (human)Potency3.916320
fenoterolHomo sapiens (human)Potency9.439210
fendiline hydrochlorideHomo sapiens (human)Potency33.491510
3,3'-diethylthiacarbocyanine iodideHomo sapiens (human)Potency3.064420
nitrovinHomo sapiens (human)Potency2.984920
22,23-dihydroavermectin b(1)aHomo sapiens (human)Potency1.678510
triphenyltin hydroxideHomo sapiens (human)Potency0.062820
lasalocid sodiumHomo sapiens (human)Potency25.490520
mg 624Homo sapiens (human)Potency11.237010
avermectin b(1)aHomo sapiens (human)Potency5.100310
diniconazoleHomo sapiens (human)Potency73.958210
everolimusHomo sapiens (human)Potency29.416820
axitinibHomo sapiens (human)Potency0.355120
su 11248Homo sapiens (human)Potency8.412710
cefpodoxime proxetilHomo sapiens (human)Potency1.496010
norgestimateHomo sapiens (human)Potency26.603210
nitrofurantoinHomo sapiens (human)Potency17.972220
bufogeninHomo sapiens (human)Potency1.968320
pd 184352Homo sapiens (human)Potency16.785510
chlorhexidineHomo sapiens (human)Potency54.873620
dectomaxHomo sapiens (human)Potency9.439210
proflavine hemisulfateHomo sapiens (human)Potency13.333220
cyazofamidHomo sapiens (human)Potency12.184710
cp 105696Homo sapiens (human)Potency76.958810
sr 271425Homo sapiens (human)Potency35.291620
hmr 1275Homo sapiens (human)Potency0.016810
(2S,3S)-nemonaprideHomo sapiens (human)Potency29.849310
pazopanibHomo sapiens (human)Potency9.302420
ptc 124Homo sapiens (human)Potency0.025720
pirarubicinHomo sapiens (human)Potency2.515720
trihexyltetradecylphosphonium chlorideHomo sapiens (human)Potency1.158120
carfilzomibHomo sapiens (human)Potency0.110120
nebivolol hydrochlorideHomo sapiens (human)Potency31.039920
decominol hydrochlorideHomo sapiens (human)Potency33.491520
tanninsHomo sapiens (human)Potency6.949020
phenylmercuric acetateHomo sapiens (human)Potency2.163120
dibutyltin diacetateHomo sapiens (human)Potency9.615420
phentin acetateHomo sapiens (human)Potency0.306410
tri-n-butylstannylmethacrylateHomo sapiens (human)Potency5.152020
thimerosalHomo sapiens (human)Potency4.733820
mk 0571Homo sapiens (human)Potency5.519720
montelukast sodiumHomo sapiens (human)Potency27.664420
monensinHomo sapiens (human)Potency0.473110
docusate sodiumHomo sapiens (human)Potency68.589610
salinomycinHomo sapiens (human)Potency0.595610
ro3280Homo sapiens (human)Potency2.040120
mobicHomo sapiens (human)Potency76.958810
bromadioloneHomo sapiens (human)Potency26.603210
chlortetracycline hydrochlorideHomo sapiens (human)Potency49.589510
nelfinavirHomo sapiens (human)Potency14.960110
clozapineHomo sapiens (human)Potency10.590910
salinazidHomo sapiens (human)Potency21.974620
heliomycinHomo sapiens (human)Potency1.333310
febantelHomo sapiens (human)Potency11.883210
2-(1-(ethoxyimino)propyl)-3-hydroxy-5-(2,4,6-trimethylphenyl)cyclohex-2-enoneHomo sapiens (human)Potency76.958810
pp242Homo sapiens (human)Potency9.815720

Enables

This protein enables 5 target(s):

TargetCategoryDefinition
protein bindingmolecular functionBinding to a protein. [GOC:go_curators]
ATP bindingmolecular functionBinding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
ATP hydrolysis activitymolecular functionCatalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. [RHEA:13065]
DNA clamp unloader activitymolecular functionFacilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis. [GOC:vw, PMID:23499004]
DNA bindingmolecular functionAny molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
nucleuscellular componentA membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]

Part Of

This protein is part of 1 target(s):

TargetCategoryDefinition
Elg1 RFC-like complexcellular componentA pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. [PMID:14614842, PMID:23499004, PMID:27664980]

Involved In

This protein is involved in 12 target(s):

TargetCategoryDefinition
cell population proliferationbiological processThe multiplication or reproduction of cells, resulting in the expansion of a cell population. [GOC:mah, GOC:mb]
positive regulation of B cell proliferationbiological processAny process that activates or increases the rate or extent of B cell proliferation. [GOC:mah]
nuclear DNA replicationbiological processThe DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. [GOC:mtg_cell_cycle]
signal transduction in response to DNA damagebiological processA cascade of processes induced by the detection of DNA damage within a cell. [GOC:go_curators]
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorbiological processThe series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. [GOC:go_curators, GOC:mtg_apoptosis]
isotype switchingbiological processThe switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. [ISBN:0781735149]
positive regulation of DNA replicationbiological processAny process that activates or increases the frequency, rate or extent of DNA replication. [GOC:go_curators]
positive regulation of isotype switching to IgG isotypesbiological processAny process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes. [GOC:jid]
DNA clamp unloadingbiological processThe process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates. [GOC:rb, PMID:23499004]
regulation of mitotic cell cycle phase transitionbiological processAny process that modulates the frequency, rate or extent of mitotic cell cycle phase transition. [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721]
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorbiological processAny process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. [GOC:TermGenie, PMID:17719541]
positive regulation of cell cycle G2/M phase transitionbiological processAny signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. [GO_REF:0000058, GOC:jl, GOC:TermGenie]
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