Page last updated: 2024-12-05

orange g

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

orange G : An organic sodium salt that is the disodium salt of 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid. It is often combined with other yellow dyes in alcoholic solution to stain erythrocytes in trichrome methods, and is used for demonstrating cells in the pancreas and pituitary. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID16015
CHEMBL ID410263
CHEBI ID82427
SCHEMBL ID81967
SCHEMBL ID340738
MeSH IDM0052800

Synonyms (157)

Synonym
disodium 7-hydroxy-8-[(z)-phenyldiazenyl]naphthalene-1,3-disulfonate
sulfacid light orange j
orange 2g
amacid crystal orange
orange g (indicator)
colacid orange g
crystal orange 2g
java orange 2g
acid orange 2g
fenazo light orange 2g
fast acid orange g
standacol orange g
erio fast orange as
nci-c53838
acid orange lightfast
acid orange gg
acid light orange j
acid lightfast orange
d and c orange no. 3
intracid fast orange g
tertracid light orange g
dolkwal orange g
straight orange g
c.i. acid orange no. 10
hispacid fast orange 2g
orange gmp
acid fast orange g
orange bpc
c.i. acid orange 10, disodium salt
orange g b.p.c
naphthalene fast orange 2g
certicol orange gs
neklacid fast light orange gg
unitertracid light orange g
orange g
hexacol orange g
neklacid fast orange gg
light orange g
acid leather orange kg
orange gg
nsc-10450
ink orange jsn
hidacid fast orange 2g
c.i. acid orange 10
acilan orange gx
xylene fast orange g
kiton fast orange g
orange #10
atul acid crystal orange g
hexacol orange gg crystals
schultz no. 39
bucacid fast orange g
food orange gg
1936-15-8
fast light orange ga
brasilan orange 2g
acid light orange ja export
acid light orange sx
c.i. 16230
neklacid fast orange 2g
acid light orange g
vendacid light orange 2g
solar light orange gx
fast light orange ga-cf
1370 orange
calcocid fast light orange 2g
eniacid light orange g
c.i. food orange 4
acid orange 10
naphthalene fast orange 2gs
cetil light orange gg
fast light orange g
vondacid light orange 2g
hidacid fast orange g
acid fast orange egg
apocid orange 2g
orange g dye
orange g (biological stain)
acid leather orange pgw
food orange 4
oranz kysela 10 [czech]
naphthalene orange solide gg
oranz gg [czech]
disodium 7-hydroxy-8-phenylazonaphthalene-1,3-disulphonate
nsc 10450
c.i. orange g
einecs 217-705-6
7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulfonic acid, disodium salt
oranz g [polish]
7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulphonic acid, disodium salt
oranz potravinarska 4 [czech]
ccris 881
1,3-naphthalenedisulfonic acid, 7-hydroxy-8-(phenylazo)-, disodium salt
disodium 7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulfonate
duasyn acid orange gg
1-phenylazo-2-naphthol-6,8-disulfonic acid, disodium salt
orange g bpc
hsdb 4348
ci 27
ci 16230
7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulfonic acid disodium salt
2-hydroxy-1-phenylazo-6,8-naphthalenedisulfonic acid, disodium salt
d&c orange no. 3
1-phenylazo-2-naphthol-6,8-disulphonic acid, disodium salt
orange g, certified by the biological stain commission
NCGC00164330-01
orange g, for na electrophoresis
CHEMBL410263
orange g sodium
chebi:82427 ,
AKOS000283092
bdbm50177800
O0093
C19372
ci orange g
oranz potravinarska 4
oranz kysela 10
unii-1q6eju80rn
1,3-naphthalenedisulfonic acid, 7-hydroxy-8-(2-phenyldiazenyl)-, sodium salt (1:2)
oranz gg
oranz g
1q6eju80rn ,
NCGC00256372-01
tox21_303019
dtxsid6021082 ,
dtxcid801474349
cas-1936-15-8
tox21_202154
NCGC00259703-01
AKOS024319578
AKOS015903035
1-phenylazo-2-naphthol-6,8-disulfonic acid disodium salt
c.i. orange g [hsdb]
ci orange g [iarc]
disodium 7-hydroxy-8-(phenylazo)-1,3-naphthalenedisulphonate
orange g [iarc]
ci 16230 [inci]
d&c orange no. 3 (delisted)
SCHEMBL81967
SCHEMBL340738
AKOS016372313
disodium 7-hydroxy-8-[(e)-phenyldiazenyl]naphthalene-1,3-disulfonate
orange g (c.i. 16230)
mfcd00012457
orange g, electrophoresis grade
orange g/blue loading dye (6x)
orange g loading dye (6x), glycerol based
orange g, certified by the biological stain commission, dye content 80 %
orange g, dye content >=60 %
J-012537
sodium (e)-7-hydroxy-8-(phenyldiazenyl)naphthalene-1,3-disulfonate
AMY22404
orangeg
sodium 7-hydroxy-8-(phenyldiazenyl)naphthalene-1,3-disulfonate
1082249-82-8
D91797
disodium;7-hydroxy-8-phenyldiazenylnaphthalene-1,3-disulfonate

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The effect of the initial pH of the solution and the dosage of hydrogen peroxide under different light sources was also investigated."( Photocatalytic degradation of Orange G on nitrogen-doped TiO2 catalysts under visible light and sunlight irradiation.
Qiao, L; Sun, J; Sun, S; Wang, G, 2008
)
0.35
"Three rapid, simple, reproducible and sensitive extractive colorimetric methods (A--C) for assaying dothiepin hydrochloride (I) and risperidone (II) in bulk sample and in dosage forms were investigated."( Extractive colorimetric method for the determination of dothiepin hydrochloride and risperidone in pure and in dosage forms.
Hassan, Wel-S, 2008
)
0.35
" The effects of various parameters such as agitation time, initial dye concentration and adsorbent dosage were studied using response surface methodology (RSM)."( Optimization of Orange G dye adsorption by activated carbon of Thespesia populnea pods using response surface methodology.
Arulkumar, M; Palvannan, T; Sathishkumar, P, 2011
)
0.37
" Moreover, the dosage of PDS and GAC, temperature and initial concentration of OG had an impact on OG oxidation, higher temperature and GAC dosage resulted in higher OG degrading rates."( [Degradation kinetics of activated carbon catalyzed persulfate oxidation orange G].
Liu, D; Yang, MM; Zheng, K; Zhou, SQ, 2013
)
0.39
" An increase in the oxidant dosage (0."( Oxidation of Orange G by persulfate activated by Fe(II), Fe(III) and zero valent iron (ZVI).
Costa, D; Rodriguez, S; Romero, A; Santos, A; Vasquez, L, 2014
)
0.4
" Preliminary experiments were carried out to study the effects of pH, catalyst dosage and initial dye concentration on the extent of dye degradation."( Nitrogen doped nanocrystalline semiconductor metal oxide: An efficient UV active photocatalyst for the oxidation of an organic dye using slurry Photoreactor.
Kumar, BD; Ramachandran, S; Sivasamy, A, 2016
)
0.43
" Cl(-) and SO4 (2-) exhibited a promoting effect on OG decolorization, and the accelerating rate increased with elevating dosage of ions."( Activated carbon fiber for heterogeneous activation of persulfate: implication for the decolorization of azo dye.
Chen, J; Hong, W; Huang, T; Li, W; Wang, Y; Zhang, L, 2016
)
0.43
" Although this method has been proven successful in testing dose-response analysis, the microliter consumption of expensive reagents and hours of reaction and analysis time call for innovative methods for improvements."( Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications.
Chan, S; Chen, X; Courtney, M; Mohamed, T; Rao, PP; Ren, CL, 2017
)
0.46
" The significant factors that affected adsorption were identified to be solution temperature, solution pH, adsorbent dosage and initial solution concentration."( Combined Homogeneous Surface Diffusion Model - Design of experiments approach to optimize dye adsorption considering both equilibrium and kinetic aspects.
Aravamudan, K; Muthukkumaran, A, 2017
)
0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (11)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency79.96570.007215.758889.3584AID1224835
acetylcholinesteraseHomo sapiens (human)Potency63.38990.002541.796015,848.9004AID1347395; AID1347398
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency0.39160.000214.376460.0339AID588532; AID720692
retinoid X nuclear receptor alphaHomo sapiens (human)Potency50.11870.000817.505159.3239AID588546
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency0.24340.001530.607315,848.9004AID1224848; AID1224849
pregnane X nuclear receptorHomo sapiens (human)Potency70.79460.005428.02631,258.9301AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency22.75420.000229.305416,493.5996AID743069; AID743075; AID743079
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency21.96070.001024.504861.6448AID743215
thyroid stimulating hormone receptorHomo sapiens (human)Potency17.22890.001628.015177.1139AID1259385
Histone H2A.xCricetulus griseus (Chinese hamster)Potency78.79650.039147.5451146.8240AID1224845
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Amyloid-beta precursor proteinHomo sapiens (human)IC50 (µMol)5.85000.00053.889510.0000AID1305341; AID1305342
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (79)

Processvia Protein(s)Taxonomy
regulation of gene expressionAmyloid-beta precursor proteinHomo sapiens (human)
cognitionAmyloid-beta precursor proteinHomo sapiens (human)
G2/M transition of mitotic cell cycleAmyloid-beta precursor proteinHomo sapiens (human)
microglial cell activationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of protein phosphorylationAmyloid-beta precursor proteinHomo sapiens (human)
suckling behaviorAmyloid-beta precursor proteinHomo sapiens (human)
astrocyte activation involved in immune responseAmyloid-beta precursor proteinHomo sapiens (human)
regulation of translationAmyloid-beta precursor proteinHomo sapiens (human)
protein phosphorylationAmyloid-beta precursor proteinHomo sapiens (human)
intracellular copper ion homeostasisAmyloid-beta precursor proteinHomo sapiens (human)
endocytosisAmyloid-beta precursor proteinHomo sapiens (human)
response to oxidative stressAmyloid-beta precursor proteinHomo sapiens (human)
cell adhesionAmyloid-beta precursor proteinHomo sapiens (human)
regulation of epidermal growth factor-activated receptor activityAmyloid-beta precursor proteinHomo sapiens (human)
Notch signaling pathwayAmyloid-beta precursor proteinHomo sapiens (human)
axonogenesisAmyloid-beta precursor proteinHomo sapiens (human)
learning or memoryAmyloid-beta precursor proteinHomo sapiens (human)
learningAmyloid-beta precursor proteinHomo sapiens (human)
mating behaviorAmyloid-beta precursor proteinHomo sapiens (human)
locomotory behaviorAmyloid-beta precursor proteinHomo sapiens (human)
axo-dendritic transportAmyloid-beta precursor proteinHomo sapiens (human)
cholesterol metabolic processAmyloid-beta precursor proteinHomo sapiens (human)
negative regulation of cell population proliferationAmyloid-beta precursor proteinHomo sapiens (human)
adult locomotory behaviorAmyloid-beta precursor proteinHomo sapiens (human)
visual learningAmyloid-beta precursor proteinHomo sapiens (human)
regulation of gene expressionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of gene expressionAmyloid-beta precursor proteinHomo sapiens (human)
negative regulation of gene expressionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of peptidyl-threonine phosphorylationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycleAmyloid-beta precursor proteinHomo sapiens (human)
microglia developmentAmyloid-beta precursor proteinHomo sapiens (human)
axon midline choice point recognitionAmyloid-beta precursor proteinHomo sapiens (human)
neuron remodelingAmyloid-beta precursor proteinHomo sapiens (human)
dendrite developmentAmyloid-beta precursor proteinHomo sapiens (human)
regulation of Wnt signaling pathwayAmyloid-beta precursor proteinHomo sapiens (human)
extracellular matrix organizationAmyloid-beta precursor proteinHomo sapiens (human)
forebrain developmentAmyloid-beta precursor proteinHomo sapiens (human)
neuron projection developmentAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of chemokine productionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of interleukin-1 beta productionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of interleukin-6 productionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of tumor necrosis factor productionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylationAmyloid-beta precursor proteinHomo sapiens (human)
ionotropic glutamate receptor signaling pathwayAmyloid-beta precursor proteinHomo sapiens (human)
regulation of multicellular organism growthAmyloid-beta precursor proteinHomo sapiens (human)
negative regulation of neuron differentiationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of glycolytic processAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of mitotic cell cycleAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of JNK cascadeAmyloid-beta precursor proteinHomo sapiens (human)
astrocyte activationAmyloid-beta precursor proteinHomo sapiens (human)
regulation of long-term neuronal synaptic plasticityAmyloid-beta precursor proteinHomo sapiens (human)
collateral sprouting in absence of injuryAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of inflammatory responseAmyloid-beta precursor proteinHomo sapiens (human)
regulation of peptidyl-tyrosine phosphorylationAmyloid-beta precursor proteinHomo sapiens (human)
regulation of synapse structure or activityAmyloid-beta precursor proteinHomo sapiens (human)
synapse organizationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of calcium-mediated signalingAmyloid-beta precursor proteinHomo sapiens (human)
neuromuscular process controlling balanceAmyloid-beta precursor proteinHomo sapiens (human)
synaptic assembly at neuromuscular junctionAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of protein metabolic processAmyloid-beta precursor proteinHomo sapiens (human)
neuron apoptotic processAmyloid-beta precursor proteinHomo sapiens (human)
smooth endoplasmic reticulum calcium ion homeostasisAmyloid-beta precursor proteinHomo sapiens (human)
neuron cellular homeostasisAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of ERK1 and ERK2 cascadeAmyloid-beta precursor proteinHomo sapiens (human)
response to interleukin-1Amyloid-beta precursor proteinHomo sapiens (human)
modulation of excitatory postsynaptic potentialAmyloid-beta precursor proteinHomo sapiens (human)
NMDA selective glutamate receptor signaling pathwayAmyloid-beta precursor proteinHomo sapiens (human)
regulation of spontaneous synaptic transmissionAmyloid-beta precursor proteinHomo sapiens (human)
cytosolic mRNA polyadenylationAmyloid-beta precursor proteinHomo sapiens (human)
negative regulation of long-term synaptic potentiationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of long-term synaptic potentiationAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transductionAmyloid-beta precursor proteinHomo sapiens (human)
cellular response to amyloid-betaAmyloid-beta precursor proteinHomo sapiens (human)
regulation of presynapse assemblyAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of amyloid fibril formationAmyloid-beta precursor proteinHomo sapiens (human)
amyloid fibril formationAmyloid-beta precursor proteinHomo sapiens (human)
neuron projection maintenanceAmyloid-beta precursor proteinHomo sapiens (human)
positive regulation of T cell migrationAmyloid-beta precursor proteinHomo sapiens (human)
central nervous system developmentAmyloid-beta precursor proteinHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (13)

Processvia Protein(s)Taxonomy
RNA polymerase II cis-regulatory region sequence-specific DNA bindingAmyloid-beta precursor proteinHomo sapiens (human)
DNA bindingAmyloid-beta precursor proteinHomo sapiens (human)
serine-type endopeptidase inhibitor activityAmyloid-beta precursor proteinHomo sapiens (human)
signaling receptor bindingAmyloid-beta precursor proteinHomo sapiens (human)
protein bindingAmyloid-beta precursor proteinHomo sapiens (human)
heparin bindingAmyloid-beta precursor proteinHomo sapiens (human)
enzyme bindingAmyloid-beta precursor proteinHomo sapiens (human)
identical protein bindingAmyloid-beta precursor proteinHomo sapiens (human)
transition metal ion bindingAmyloid-beta precursor proteinHomo sapiens (human)
receptor ligand activityAmyloid-beta precursor proteinHomo sapiens (human)
PTB domain bindingAmyloid-beta precursor proteinHomo sapiens (human)
protein serine/threonine kinase bindingAmyloid-beta precursor proteinHomo sapiens (human)
signaling receptor activator activityAmyloid-beta precursor proteinHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (41)

Processvia Protein(s)Taxonomy
extracellular spaceAmyloid-beta precursor proteinHomo sapiens (human)
dendriteAmyloid-beta precursor proteinHomo sapiens (human)
extracellular regionAmyloid-beta precursor proteinHomo sapiens (human)
extracellular spaceAmyloid-beta precursor proteinHomo sapiens (human)
nuclear envelope lumenAmyloid-beta precursor proteinHomo sapiens (human)
cytoplasmAmyloid-beta precursor proteinHomo sapiens (human)
mitochondrial inner membraneAmyloid-beta precursor proteinHomo sapiens (human)
endosomeAmyloid-beta precursor proteinHomo sapiens (human)
early endosomeAmyloid-beta precursor proteinHomo sapiens (human)
endoplasmic reticulumAmyloid-beta precursor proteinHomo sapiens (human)
endoplasmic reticulum lumenAmyloid-beta precursor proteinHomo sapiens (human)
smooth endoplasmic reticulumAmyloid-beta precursor proteinHomo sapiens (human)
Golgi apparatusAmyloid-beta precursor proteinHomo sapiens (human)
Golgi lumenAmyloid-beta precursor proteinHomo sapiens (human)
Golgi-associated vesicleAmyloid-beta precursor proteinHomo sapiens (human)
cytosolAmyloid-beta precursor proteinHomo sapiens (human)
plasma membraneAmyloid-beta precursor proteinHomo sapiens (human)
clathrin-coated pitAmyloid-beta precursor proteinHomo sapiens (human)
cell-cell junctionAmyloid-beta precursor proteinHomo sapiens (human)
synaptic vesicleAmyloid-beta precursor proteinHomo sapiens (human)
cell surfaceAmyloid-beta precursor proteinHomo sapiens (human)
membraneAmyloid-beta precursor proteinHomo sapiens (human)
COPII-coated ER to Golgi transport vesicleAmyloid-beta precursor proteinHomo sapiens (human)
axonAmyloid-beta precursor proteinHomo sapiens (human)
growth coneAmyloid-beta precursor proteinHomo sapiens (human)
platelet alpha granule lumenAmyloid-beta precursor proteinHomo sapiens (human)
neuromuscular junctionAmyloid-beta precursor proteinHomo sapiens (human)
endosome lumenAmyloid-beta precursor proteinHomo sapiens (human)
trans-Golgi network membraneAmyloid-beta precursor proteinHomo sapiens (human)
ciliary rootletAmyloid-beta precursor proteinHomo sapiens (human)
dendritic spineAmyloid-beta precursor proteinHomo sapiens (human)
dendritic shaftAmyloid-beta precursor proteinHomo sapiens (human)
perikaryonAmyloid-beta precursor proteinHomo sapiens (human)
membrane raftAmyloid-beta precursor proteinHomo sapiens (human)
apical part of cellAmyloid-beta precursor proteinHomo sapiens (human)
synapseAmyloid-beta precursor proteinHomo sapiens (human)
perinuclear region of cytoplasmAmyloid-beta precursor proteinHomo sapiens (human)
presynaptic active zoneAmyloid-beta precursor proteinHomo sapiens (human)
spindle midzoneAmyloid-beta precursor proteinHomo sapiens (human)
recycling endosomeAmyloid-beta precursor proteinHomo sapiens (human)
extracellular exosomeAmyloid-beta precursor proteinHomo sapiens (human)
receptor complexAmyloid-beta precursor proteinHomo sapiens (human)
early endosomeAmyloid-beta precursor proteinHomo sapiens (human)
membrane raftAmyloid-beta precursor proteinHomo sapiens (human)
cell surfaceAmyloid-beta precursor proteinHomo sapiens (human)
Golgi apparatusAmyloid-beta precursor proteinHomo sapiens (human)
plasma membraneAmyloid-beta precursor proteinHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1542227Inhibition of synthetic AcPHF6 peptide aggregation in pH 7.4 phosphate buffer assessed as reduction in fluorescence intensity at 50 uM and measured every minute over 2 hrs with 5 secs shaking prior to each reading by ThT fluorescence assay2019European journal of medicinal chemistry, Apr-01, Volume: 167Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6.
AID1305341Inhibition of self-induced amyloid beta 40 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysis2016ACS medicinal chemistry letters, May-12, Volume: 7, Issue:5
Structure-Activity Relationship Studies of Isomeric 2,4-Diaminoquinazolines on β-Amyloid Aggregation Kinetics.
AID322958Inhibition of synthetic amyloid beta-42 fibrillation by light scattering analysis relative to control2007The Journal of biological chemistry, Apr-06, Volume: 282, Issue:14
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
AID1305342Inhibition of self-induced amyloid beta 42 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysis2016ACS medicinal chemistry letters, May-12, Volume: 7, Issue:5
Structure-Activity Relationship Studies of Isomeric 2,4-Diaminoquinazolines on β-Amyloid Aggregation Kinetics.
AID322957Inhibition of synthetic amyloid beta-42 fibrillation by ThT fluorescence analysis relative to control2007The Journal of biological chemistry, Apr-06, Volume: 282, Issue:14
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (115)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (7.83)18.7374
1990's9 (7.83)18.2507
2000's34 (29.57)29.6817
2010's49 (42.61)24.3611
2020's14 (12.17)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (0.83%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other119 (99.17%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]