Page last updated: 2024-08-07 18:35:47
Solute carrier organic anion transporter family member 1A1
A solute carrier organic anion transporter family member 1A1 that is encoded in the genome of rat. [OMA:P46720, PRO:DNx]
Synonyms
Organic anion-transporting polypeptide 1;
OATP-1;
Sodium-independent organic anion transporter 1;
Solute carrier family 21 member 1
Research
Bioassay Publications (18)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (72.22) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (35)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ibuprofen | Rattus norvegicus (Norway rat) | Ki | 126.0000 | 1 | 1 |
| probenecid | Rattus norvegicus (Norway rat) | Ki | 74.4000 | 1 | 1 |
| corticosterone | Rattus norvegicus (Norway rat) | Ki | 5.3000 | 1 | 1 |
| estriol | Rattus norvegicus (Norway rat) | Ki | 9.8000 | 1 | 1 |
| estrone | Rattus norvegicus (Norway rat) | Ki | 15.7000 | 1 | 1 |
| androsterone | Rattus norvegicus (Norway rat) | Ki | 10.6000 | 1 | 1 |
| sulfobromophthalein sodium | Rattus norvegicus (Norway rat) | Ki | 1.9800 | 1 | 1 |
| taurocholic acid | Rattus norvegicus (Norway rat) | Ki | 21.4000 | 2 | 2 |
| estradiol-3-sulfate | Rattus norvegicus (Norway rat) | Ki | 1.1000 | 1 | 1 |
| ethinyl estradiol-17-sulfate | Rattus norvegicus (Norway rat) | Ki | 1.3000 | 1 | 1 |
| testosterone 17-glucosiduronate | Rattus norvegicus (Norway rat) | Ki | 3.8000 | 1 | 1 |
| androsterone sulfate | Rattus norvegicus (Norway rat) | Ki | 2.4000 | 1 | 1 |
| corticosterone sulfate | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| estradiol-3-glucuronide | Rattus norvegicus (Norway rat) | Ki | 9.7000 | 1 | 1 |
| quinidine | Rattus norvegicus (Norway rat) | Ki | 9.2700 | 1 | 1 |
| estrone sulfate | Rattus norvegicus (Norway rat) | Ki | 1.3000 | 1 | 1 |
| quinine | Rattus norvegicus (Norway rat) | Ki | 76.7000 | 1 | 1 |
| rifamycin sv | Rattus norvegicus (Norway rat) | Ki | 6.6000 | 1 | 1 |
| rifampin | Rattus norvegicus (Norway rat) | Ki | 18.2000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| fexofenadine | Rattus norvegicus (Norway rat) | Km | 32.0000 | 1 | 1 |
| aldosterone | Rattus norvegicus (Norway rat) | Km | 0.0150 | 1 | 1 |
| sulfobromophthalein sodium | Rattus norvegicus (Norway rat) | Km | 2.6000 | 3 | 2 |
| taurocholic acid | Rattus norvegicus (Norway rat) | Km | 36.5200 | 4 | 5 |
| glycocholic acid | Rattus norvegicus (Norway rat) | Km | 54.0000 | 1 | 1 |
| dehydroepiandrosterone sulfate | Rattus norvegicus (Norway rat) | Km | 5.0000 | 1 | 1 |
| pravastatin | Rattus norvegicus (Norway rat) | Km | 30.0000 | 1 | 1 |
| taurochenodeoxycholic acid | Rattus norvegicus (Norway rat) | Km | 5.9500 | 2 | 1 |
| ouabain | Rattus norvegicus (Norway rat) | Km | 2,350.0000 | 2 | 2 |
| ochratoxin a | Rattus norvegicus (Norway rat) | Km | 22.8000 | 2 | 2 |
| temocaprilat | Rattus norvegicus (Norway rat) | Km | 46.7000 | 1 | 1 |
| bq 123 | Rattus norvegicus (Norway rat) | Km | 600.0000 | 1 | 1 |
| sodium taurodeoxycholate | Rattus norvegicus (Norway rat) | Km | 3.5000 | 1 | 1 |
| estrone sulfate | Rattus norvegicus (Norway rat) | Km | 7.7500 | 2 | 2 |
| estradiol-17 beta-glucuronide | Rattus norvegicus (Norway rat) | Km | 7.9114 | 7 | 7 |
| hyodeoxycholic acid | Rattus norvegicus (Norway rat) | Km | 17.5000 | 1 | 1 |
| enalapril | Rattus norvegicus (Norway rat) | Km | 252.0000 | 1 | 1 |
| ursodoxicoltaurine | Rattus norvegicus (Norway rat) | Km | 13.0000 | 1 | 1 |
| deltorphin ii, ala(2)- | Rattus norvegicus (Norway rat) | Km | 137.0000 | 1 | 1 |