Page last updated: 2024-08-07 16:06:49
Androgen receptor
An androgen receptor that is encoded in the genome of mouse. [OMA:P19091, PRO:DNx]
Synonyms
Dihydrotestosterone receptor;
Nuclear receptor subfamily 3 group C member 4
Research
Bioassay Publications (11)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
Compounds (14)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| bicalutamide | Mus musculus (house mouse) | IC50 | 1.8350 | 2 | 2 |
| dihydrotestosterone | Mus musculus (house mouse) | IC50 | 0.0010 | 1 | 1 |
| hydroxyflutamide | Mus musculus (house mouse) | IC50 | 0.6073 | 3 | 3 |
| 17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one | Mus musculus (house mouse) | IC50 | 0.4630 | 1 | 1 |
| lg190155 | Mus musculus (house mouse) | IC50 | 1.9000 | 1 | 1 |
| lg190178 | Mus musculus (house mouse) | IC50 | 0.0190 | 1 | 1 |
| 5-(2,5-difluorophenyl)-N-(2,6-dimethylphenyl)-2-furancarboxamide | Mus musculus (house mouse) | IC50 | 25.0000 | 1 | 0 |
| 5-(2,5-dichlorophenyl)-N-(2,6-dimethoxyphenyl)-2-furancarboxamide | Mus musculus (house mouse) | IC50 | 10.5400 | 1 | 0 |
| 5-(2,5-dichlorophenyl)-N-[2,6-di(propan-2-yl)phenyl]-2-furancarboxamide | Mus musculus (house mouse) | IC50 | 25.0000 | 1 | 0 |
| 5-(2,5-dichlorophenyl)-N-(2,6-diethylphenyl)-2-furancarboxamide | Mus musculus (house mouse) | IC50 | 25.0000 | 1 | 0 |
| N-(2,6-dimethylphenyl)-5-(4-methyl-3-thiophenyl)-2-furancarboxamide | Mus musculus (house mouse) | IC50 | 25.0000 | 1 | 0 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| testosterone propionate | Mus musculus (house mouse) | EC50 | 0.0028 | 1 | 1 |
| medroxyprogesterone acetate | Mus musculus (house mouse) | EC50 | 0.0061 | 2 | 2 |
| dihydrotestosterone | Mus musculus (house mouse) | EC50 | 0.0040 | 1 | 1 |
| bms-564929 | Mus musculus (house mouse) | EC50 | 0.0014 | 2 | 2 |