Genome polyprotein

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
erythrosine	Zika virus	IC50	1.7000	1	1
hydroxychloroquine	Zika virus	Ki	92.3000	1	1
bromocriptine	Zika virus	IC50	17.3200	2	2
epigallocatechin gallate	Zika virus	IC50	87.0000	1	1
epicatechin gallate	Zika virus	IC50	89.0000	1	1
(-)-gallocatechin gallate	Zika virus	IC50	99.0000	1	1
benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester	Zika virus	IC50	1.5000	1	1
luteolin	Zika virus	IC50	53.0000	1	1
rutin	Zika virus	IC50	104.0000	1	1
myricetin	Zika virus	IC50	11.6500	2	2
myricetin	Zika virus	Ki	0.8000	1	1
astragalin	Zika virus	IC50	112.0000	1	1
at 406	Zika virus	IC50	4.1000	1	1
at 406	Zika virus	Ki	13.5000	1	1
novobiocin	Zika virus	IC50	14.2000	1	1
temoporfin	Zika virus	IC50	1.1000	1	1

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
erythrosine	Zika virus	EC50	0.6000	1	1
bromocriptine	Zika virus	EC50	13.0200	2	2
at 406	Zika virus	Kd	9.0000	1	1
birinapant	Zika virus	EC50	0.3000	1	1
novobiocin	Zika virus	EC50	24.8000	1	1
temoporfin	Zika virus	EC50	0.0220	1	1

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
temoporfin	Zika virus	EC90	0.1200	1	1

Inhibitors of the Zika virus protease NS2B-NS3.
Bioorganic & medicinal chemistry letters, , 03-01, Volume: 30, Issue:5, 2020

Drugs for the Treatment of Zika Virus Infection.
Journal of medicinal chemistry, , 01-23, Volume: 63, Issue:2, 2020

Inhibitors of the Zika virus protease NS2B-NS3.
Bioorganic & medicinal chemistry letters, , 03-01, Volume: 30, Issue:5, 2020

Cell-active carbazole derivatives as inhibitors of the zika virus protease.
European journal of medicinal chemistry, , Oct-15, Volume: 180, 2019

Drugs for the Treatment of Zika Virus Infection.
Journal of medicinal chemistry, , 01-23, Volume: 63, Issue:2, 2020

Inhibitors of the Zika virus protease NS2B-NS3.
Bioorganic & medicinal chemistry letters, , 03-01, Volume: 30, Issue:5, 2020

Research