liquiritigenin profile

liquiritigenin: structure given in first source; isolated from Pterocarpus marsupium [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

4',7-dihydroxyflavanone : A dihydroxyflavanone in which the two hydroxy substituents are located at positions 4' and 7. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

liquiritigenin : A dihydroxyflavanone compound having the two hydroxy substituents at the 4'- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Related Flora

Pathways (3)

liquiritigenin is involved in 3 pathway(s), involving a total of 4 unique proteins and 72 unique compounds

Flora	Rank	Flora Definition	Family	Family Definition
Pterocarpus	genus	A plant genus of the family FABACEAE. Members contain TRITERPENES.[MeSH]	Fabaceae	The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH]
Pterocarpus marsupium	species	[no description available]	Fabaceae	The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH]

ID Source	ID
PubMed CID	114829
CHEMBL ID	252642
CHEBI ID	28777
SCHEMBL ID	74552
MeSH ID	M0221321

Synonym
4h-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (2s)-
7,4'-dihydroxyflavanone
DFV ,
7-hydroxy-2-(4-hydroxy-phenyl)-chroman-4-one
4',7-dihydroxyflavanone
C09762
liquiritigenin
578-86-9
DB03601
5-deoxyflavanone
(2s)-liquiritigenin
LMPK12140061
bdbm50241408
(2s)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4h-chromen-4-one
(-)-liquiritigenin
CHEBI:28777 ,
(2s)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4h-1-benzopyran-4-one
CHEMBL252642 ,
liquirtigenin
(2s)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
A831662
(2s)-7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-1-benzopyran-4-one
A826663
(2s)-2-(4-hydroxyphenyl)-7-oxidanyl-2,3-dihydrochromen-4-one
4h-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (s)-
menerba
t194lkp9w6 ,
mf101
unii-t194lkp9w6
S3929
AKOS015903151
flavanone, 4',7-dihydroxy-
liquiritigenin [inci]
(-)-(2s)-7,4'-dihydroxyflavanone
SCHEMBL74552
(2s)-7-hydroxy-2-(4-hydroxyphenyl)chroman-4-one
(s)-7-hydroxy-2-(4-hydroxyphenyl)chroman-4-one ,
FURUXTVZLHCCNA-AWEZNQCLSA-N
(s)-2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one
AC-33949
DTXSID90206493 ,
(s)-liquiritigenin
gtpl8899
liquiritigenin, >=97.0% (hplc)
NCGC00370972-01
HY-N0377
CS-6977
BCP18371
AS-18739
Q6557526
mf-101
CCG-267019
4h-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-,(2s)-
A869565
STL578166
GLXC-13419
dtxcid90128984

Excerpt	Reference
"Liquiritigenin (LQG) is a natural flavonoid from the herb Glycyrrhiza uralensis Fisch that exhibits multiple biological activities. "	( Ali, A; Qin, H; Song, Z; Wang, L; Xia, F; Yang, J; Zhao, C; Zheng, W, 2022)
"Liquiritigenin (LG) is a triterpene with anti-inflammatory properties."	( Cao, J; Ni, Y; Ning, X; Zhang, H, 2023)
"Liquiritigenin is a flavonoid extracted from Glycyrrhiza glabra roots which has been reported to have positive effects in vitro on osteoblasts activity and bone mineralization as well as inhibitory effect on osteoclasts differentiation and activity in vitro."	( Banfi, G; Carnovali, M; Mariotti, M, 2020)
"Liquiritigenin (LQ) is a major active component of licorice root, which is a flavone used for treating many diseases, including diabetes. "	( Bae, GD; Baek, DJ; Jun, HS; Oh, YS; Park, EY, 2018)
"Liquiritigenin (LQ) is an aglycone of liquiritin and has been reported to protect the liver from injury. "	( Baek, SY; Jang, EJ; Kim, KY; Kim, SC; Kim, YW; Ku, SK; Lee, EH; Lee, JH; Park, JY; Park, KI; Suk, HY, 2019)
"Liquiritigenin (LQ) is a flavanone extracted from glycyrrhizae. "	( Cai, Y; Chen, Z; Gu, D; Shi, H; Wang, Y; Wu, Y; Yan, S; Zhou, M, 2015)
"Liquiritigenin is a plant-derived flavonoid and has various pharmacological effects, such as antioxidative, antitumor, and antiinflammatory effects."	( Fukuma, Y; Iwatake, M; Nishishita, K; Okamoto, K; Sakai, E; Tsukuba, T; Uchino, K; Yoneshima, E, 2015)
"Liquiritigenin (LQ) is an active flavonoid in licorice and plays a role in the liver as a hepatic protectant."	( Jung, EH; Kim, SC; Kim, YW; Lee, JH, 2017)
"Liquiritigenin is a flavanone, isolated from Radix glycyrrhiza, which exhibits various biological properties, including anti-cancer and anti-inflammatory activities."	( Xie, XW, 2017)
"Liquiritigenin is a flavanone existed in Radix glycyrrhizae. "	( Cai, YQ; Liu, Y; Zhang, SP; Zhou, YJ, 2009)
"Liquiritigenin (LQ) is a candidate for the treatment of inflammatory liver disease. "	( Baek, SR; Kang, HE; Lee, JW; Lee, MG; Sohn, SI, 2010)
"Liquiritigenin is a flavanone extracted from Glycyrrhizae."	( Cai, Y; Li, X; Liu, C; Ren, X; Wang, Y; Xie, S; Zhou, Y, 2011)
"Liquiritigenin (LQ) is a non-toxic dietary flavonoid with chemopreventive and anticancer properties. "	( Cai, YQ; Liu, CW; Luo, K; Wang, Y; Xie, SR, 2012)
"Liquiritigenin (LQ) is a flavanone extracted from Glycyrrhizae, which has multiple biological effects, such as antiinflammation and anticancer. "	( Cai, Y; Liu, C; Liu, Y; Wang, Y; Wu, Y; Xie, S, 2012)

Excerpt	Reference
"Liquiritigenin has been isolated and identified from Sargassum pallidum."	( Guan, L; Jia, J; Jiang, H; Peng, D; Zhang, L, 2021)
"Liquiritigenin (LQ) has protective effects against various hepatotoxicities. "	( Chu, L; Chu, X; Han, X; Li, L; Wu, Y; Wu, Z; Xue, Y; Zhang, J; Zhang, M; Zhao, Y; Zheng, B, 2021)

Excerpt	Reference
"Liquiritigenin treatment of zebrafish embryo significantly enhances the osteogenesis during development in a dose-dependent manner."	( Banfi, G; Carnovali, M; Mariotti, M, 2020)
"Liquiritigenin treatment also resulted in increased apoptosis and enhanced Caspase3 activity."	( Cheng, D; Du, J; Du, P; Gao, H; Liang, F; Yin, L; Yue, J; Zhang, H; Zhang, N; Zhao, B, 2021)
"Liquiritigenin-treated murine osteoblastic MC3T3-E1 cells showed an increased alkaline phosphatase activity and enhanced phosphorylation of Smad1/5 compared with untreated cells."	( Fukuma, Y; Iwatake, M; Nishishita, K; Okamoto, K; Sakai, E; Tsukuba, T; Uchino, K; Yoneshima, E, 2015)
"Liquiritigenin treatment also attenuated Abeta(25-35)-induced increases in [Ca(2+)](i) and ROS level and decreased the apoptotic rate of neurons."	( Liu, RT; Lü, QJ; Zou, LB, 2009)
"Liquiritigenin treatment prevented LPS from increasing the levels of iNOS protein and mRNA in a concentration-dependent manner."	( Cho, IJ; Kim, SC; Kim, SG; Kim, YW; Lee, JR; Park, SJ; Yang, CH; Zhao, RJ, 2008)
"Pretreatment with liquiritigenin prior to antimycin A exposure significantly reduced antimycin A-induced PI3K inactivation, mitochondrial membrane potential dissipation, complex IV inactivation, and ATP loss."	( Choi, EM; Lee, YS; Suh, KS, 2014)
"Pretreatment with liquiritigenin prior to MG exposure reduced MG-induced mitochondrial dysfunction by preventing mitochondrial membrane potential dissipation and adenosine triphosphate loss."	( Choi, EM; Kim, YS; Rhee, SY; Suh, KS, 2014)
"Treatment with liquiritigenin resulted in a significant decrease of CXCR4 protein expression."	( Emons, G; Girgert, R; Gründker, C; Hinsche, O, 2015)
"Mice treated with liquiritigenin showed restored levels of neurotransmitter norepinephrine (NE) and serotonin (5-HT)."	( Chen, C; Chen, G; Chen, Y; Dong, Y; Duan, J; Su, Q; Tao, W; Wang, H; Xia, B; Xue, W, 2016)
"Treatment with liquiritigenin induced an elongated mitochondrial morphology in SK-N-MC cells."	( Bae, JE; Cho, DH; Jo, DS; Kim, JB; Kim, JS; Oh, JS; Park, NY; Park, SJ; Shin, DW; Shin, JW, 2016)

Role	Description
hormone agonist	A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
plant metabolite	Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
4',7-dihydroxyflavanone	A dihydroxyflavanone in which the two hydroxy substituents are located at positions 4' and 7.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathway	Proteins	Compounds
echinatin biosynthesis	0	10
6,7,4'-trihydroxyisoflavone biosynthesis	1	6
isoflavonoid biosynthesis I	0	14
isoflavonoid biosynthesis I	1	20
6,7,4'-trihydroxyisoflavone biosynthesis	2	6
6,7,4'-Trihydroxyisoflavone biosynthesis	0	6

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	16.9330	0.0123	7.9835	43.2770	AID1645841
G	Vesicular stomatitis virus	Potency	11.9877	0.0123	8.9648	39.8107	AID1645842
Interferon beta	Homo sapiens (human)	Potency	11.9877	0.0033	9.1582	39.8107	AID1645842
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	11.9877	0.0123	8.9648	39.8107	AID1645842
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	11.9877	0.0123	8.9648	39.8107	AID1645842
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	11.9877	0.0123	8.9648	39.8107	AID1645842
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50 (µMol)	5.2000	0.0000	0.5035	10.0000	AID1073043; AID1073044
Acetylcholinesterase	Electrophorus electricus (electric eel)	IC50 (µMol)	9.1000	0.0000	0.9453	9.9400	AID1809143
Tyrosine-protein kinase Yes	Homo sapiens (human)	IC50 (µMol)	11.3000	0.0004	0.5740	8.9000	AID1649932
Aromatase	Homo sapiens (human)	IC50 (µMol)	1.2200	0.0000	1.2904	10.0000	AID321164; AID387613
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)	IC50 (µMol)	70.0000	0.0005	3.4984	9.7600	AID379219; AID447165; AID612168
Proteasome subunit beta type-5	Homo sapiens (human)	IC50 (µMol)	100.0000	0.0005	0.9394	10.0000	AID1633148
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	IC50 (µMol)	11.3000	0.0030	3.1015	9.8000	AID338975
Cholinesterase	Equus caballus (horse)	IC50 (µMol)	14.0400	0.0000	2.2214	9.4000	AID1809144
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Estrogen receptor beta	Homo sapiens (human)	EC50 (µMol)	0.0365	0.0000	0.4795	4.8900	AID1855801
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell activation involved in immune response	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to virus	Interferon beta	Homo sapiens (human)
positive regulation of autophagy	Interferon beta	Homo sapiens (human)
cytokine-mediated signaling pathway	Interferon beta	Homo sapiens (human)
natural killer cell activation	Interferon beta	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Interferon beta	Homo sapiens (human)
cellular response to interferon-beta	Interferon beta	Homo sapiens (human)
B cell proliferation	Interferon beta	Homo sapiens (human)
negative regulation of viral genome replication	Interferon beta	Homo sapiens (human)
innate immune response	Interferon beta	Homo sapiens (human)
positive regulation of innate immune response	Interferon beta	Homo sapiens (human)
regulation of MHC class I biosynthetic process	Interferon beta	Homo sapiens (human)
negative regulation of T cell differentiation	Interferon beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Interferon beta	Homo sapiens (human)
defense response to virus	Interferon beta	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interferon beta	Homo sapiens (human)
neuron cellular homeostasis	Interferon beta	Homo sapiens (human)
cellular response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
cellular response to virus	Interferon beta	Homo sapiens (human)
negative regulation of Lewy body formation	Interferon beta	Homo sapiens (human)
negative regulation of T-helper 2 cell cytokine production	Interferon beta	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell differentiation	Interferon beta	Homo sapiens (human)
natural killer cell activation involved in immune response	Interferon beta	Homo sapiens (human)
adaptive immune response	Interferon beta	Homo sapiens (human)
T cell activation involved in immune response	Interferon beta	Homo sapiens (human)
humoral immune response	Interferon beta	Homo sapiens (human)
positive regulation of T cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
adaptive immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of T cell anergy	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
defense response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
detection of bacterium	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-12 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-6 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protection from natural killer cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
innate immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of dendritic cell differentiation	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of glucose transmembrane transport	Tyrosine-protein kinase Yes	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase Yes	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of vascular permeability	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase Yes	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
negative regulation of chronic inflammatory response	Aromatase	Homo sapiens (human)
steroid biosynthetic process	Aromatase	Homo sapiens (human)
estrogen biosynthetic process	Aromatase	Homo sapiens (human)
androgen catabolic process	Aromatase	Homo sapiens (human)
syncytium formation	Aromatase	Homo sapiens (human)
negative regulation of macrophage chemotaxis	Aromatase	Homo sapiens (human)
sterol metabolic process	Aromatase	Homo sapiens (human)
female genitalia development	Aromatase	Homo sapiens (human)
mammary gland development	Aromatase	Homo sapiens (human)
uterus development	Aromatase	Homo sapiens (human)
prostate gland growth	Aromatase	Homo sapiens (human)
testosterone biosynthetic process	Aromatase	Homo sapiens (human)
positive regulation of estradiol secretion	Aromatase	Homo sapiens (human)
female gonad development	Aromatase	Homo sapiens (human)
response to estradiol	Aromatase	Homo sapiens (human)
positive regulation of JUN kinase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein dephosphorylation	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
insulin receptor signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
regulation of signal transduction	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of signal transduction	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
actin cytoskeleton organization	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
regulation of endocytosis	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
endoplasmic reticulum unfolded protein response	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
regulation of intracellular protein transport	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cellular response to unfolded protein	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
peptidyl-tyrosine dephosphorylation	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
IRE1-mediated unfolded protein response	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
insulin receptor recycling	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of MAP kinase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
regulation of type I interferon-mediated signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
positive regulation of protein tyrosine kinase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
regulation of hepatocyte growth factor receptor signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
positive regulation of IRE1-mediated unfolded protein response	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
negative regulation of PERK-mediated unfolded protein response	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
positive regulation of receptor catabolic process	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
proteolysis	Proteasome subunit beta type-5	Homo sapiens (human)
response to oxidative stress	Proteasome subunit beta type-5	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Proteasome subunit beta type-5	Homo sapiens (human)
xanthine catabolic process	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
inositol phosphate metabolic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Estrogen receptor beta	Homo sapiens (human)
regulation of DNA-templated transcription	Estrogen receptor beta	Homo sapiens (human)
signal transduction	Estrogen receptor beta	Homo sapiens (human)
cell-cell signaling	Estrogen receptor beta	Homo sapiens (human)
negative regulation of cell growth	Estrogen receptor beta	Homo sapiens (human)
intracellular estrogen receptor signaling pathway	Estrogen receptor beta	Homo sapiens (human)
positive regulation of DNA-templated transcription	Estrogen receptor beta	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Estrogen receptor beta	Homo sapiens (human)
cellular response to estradiol stimulus	Estrogen receptor beta	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Estrogen receptor beta	Homo sapiens (human)
cellular response to estrogen stimulus	Estrogen receptor beta	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
cytokine activity	Interferon beta	Homo sapiens (human)
cytokine receptor binding	Interferon beta	Homo sapiens (human)
type I interferon receptor binding	Interferon beta	Homo sapiens (human)
protein binding	Interferon beta	Homo sapiens (human)
chloramphenicol O-acetyltransferase activity	Interferon beta	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
signaling receptor binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
peptide antigen binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein-folding chaperone binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
iron ion binding	Aromatase	Homo sapiens (human)
steroid hydroxylase activity	Aromatase	Homo sapiens (human)
electron transfer activity	Aromatase	Homo sapiens (human)
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Aromatase	Homo sapiens (human)
oxygen binding	Aromatase	Homo sapiens (human)
heme binding	Aromatase	Homo sapiens (human)
aromatase activity	Aromatase	Homo sapiens (human)
RNA binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein tyrosine phosphatase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
insulin receptor binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
zinc ion binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
enzyme binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein kinase binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
receptor tyrosine kinase binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cadherin binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein phosphatase 2A binding	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
non-membrane spanning protein tyrosine phosphatase activity	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
threonine-type endopeptidase activity	Proteasome subunit beta type-5	Homo sapiens (human)
protein binding	Proteasome subunit beta type-5	Homo sapiens (human)
peptidase activity	Proteasome subunit beta type-5	Homo sapiens (human)
endopeptidase activity	Proteasome subunit beta type-5	Homo sapiens (human)
xanthine dehydrogenase activity	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
xanthine oxidase activity	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
iron ion binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
molybdenum ion binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
protein homodimerization activity	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
molybdopterin cofactor binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
flavin adenine dinucleotide binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
2 iron, 2 sulfur cluster binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
FAD binding	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
inositol-1,3,4,5,6-pentakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol heptakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
ATP binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 1-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 3-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Estrogen receptor beta	Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specific	Estrogen receptor beta	Homo sapiens (human)
DNA binding	Estrogen receptor beta	Homo sapiens (human)
nuclear steroid receptor activity	Estrogen receptor beta	Homo sapiens (human)
nuclear receptor activity	Estrogen receptor beta	Homo sapiens (human)
steroid binding	Estrogen receptor beta	Homo sapiens (human)
protein binding	Estrogen receptor beta	Homo sapiens (human)
zinc ion binding	Estrogen receptor beta	Homo sapiens (human)
enzyme binding	Estrogen receptor beta	Homo sapiens (human)
nuclear estrogen receptor activity	Estrogen receptor beta	Homo sapiens (human)
estrogen response element binding	Estrogen receptor beta	Homo sapiens (human)
receptor antagonist activity	Estrogen receptor beta	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular space	Interferon beta	Homo sapiens (human)
extracellular region	Interferon beta	Homo sapiens (human)
Golgi membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
endoplasmic reticulum	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
Golgi apparatus	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
cell surface	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
ER to Golgi transport vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
secretory granule membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
phagocytic vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
early endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
recycling endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular exosome	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
lumenal side of endoplasmic reticulum membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
MHC class I protein complex	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular space	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
external side of plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Yes	Homo sapiens (human)
centrosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Yes	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase Yes	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
endoplasmic reticulum	Aromatase	Homo sapiens (human)
endoplasmic reticulum membrane	Aromatase	Homo sapiens (human)
membrane	Aromatase	Homo sapiens (human)
endoplasmic reticulum	Aromatase	Homo sapiens (human)
plasma membrane	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cytoplasm	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
mitochondrial matrix	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
early endosome	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
endoplasmic reticulum	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cytosol	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
mitochondrial crista	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
endosome lumen	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
sorting endosome	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cytoplasmic side of endoplasmic reticulum membrane	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
protein-containing complex	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
endoplasmic reticulum	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
cytoplasm	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
early endosome	Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)
nucleus	Proteasome subunit beta type-5	Homo sapiens (human)
cytoplasm	Proteasome subunit beta type-5	Homo sapiens (human)
proteasome complex	Proteasome subunit beta type-5	Homo sapiens (human)
nucleus	Proteasome subunit beta type-5	Homo sapiens (human)
nucleoplasm	Proteasome subunit beta type-5	Homo sapiens (human)
centrosome	Proteasome subunit beta type-5	Homo sapiens (human)
cytosol	Proteasome subunit beta type-5	Homo sapiens (human)
extracellular exosome	Proteasome subunit beta type-5	Homo sapiens (human)
proteasome core complex	Proteasome subunit beta type-5	Homo sapiens (human)
proteasome core complex, beta-subunit complex	Proteasome subunit beta type-5	Homo sapiens (human)
cytosol	Proteasome subunit beta type-5	Homo sapiens (human)
extracellular space	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
peroxisome	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
xanthine dehydrogenase complex	Xanthine dehydrogenase/oxidase	Bos taurus (cattle)
fibrillar center	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytosol	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleus	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleus	Estrogen receptor beta	Homo sapiens (human)
nucleoplasm	Estrogen receptor beta	Homo sapiens (human)
mitochondrion	Estrogen receptor beta	Homo sapiens (human)
intracellular membrane-bounded organelle	Estrogen receptor beta	Homo sapiens (human)
chromatin	Estrogen receptor beta	Homo sapiens (human)
nucleus	Estrogen receptor beta	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (131)

Assay ID	Title	Year	Journal	Article
AID378533	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	2005	Journal of natural products, Mar, Volume: 68, Issue:3	Cytotoxic flavonoids from Platymiscium floribundum.
AID1073043	Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assay	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID404181	Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID422532	Inhibition of melanin synthesis in NHEM after 24 hrs by liquid scintillation	2009	Journal of natural products, Jan, Volume: 72, Issue:1	Melanin synthesis inhibitors from Lespedeza cyrtobotrya.
AID626863	Antibacterial activity against Prevotella intermedia ATCC 25611 at 40 ug/ml assessed as growth inhibition by microdilution technique relative to untreated control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID404184	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID404179	Cytotoxicity against mouse colon 26-L5 cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID612168	Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 mins	2011	Bioorganic & medicinal chemistry, Jun-01, Volume: 19, Issue:11	New 5-deoxyflavonoids and their inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) activity.
AID387613	Inhibition of human aromatase by fluorometric assay	2008	Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18	Screening of herbal constituents for aromatase inhibitory activity.
AID404180	Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID1875269	Inhibition of MMP13 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID626957	Antibacterial activity against Prevotella intermedia ATCC 25611 by microdilution technique in presence of 10% unstimulated whole salive	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID339156	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as serum HDLC level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID404183	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID1453625	Inhibition of mushroom tyrosinase at 10 uM using L-tyrosine as substrate incubated for 15 mins followed by substrate addition relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID494422	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	2010	European journal of medicinal chemistry, Aug, Volume: 45, Issue:8	Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.
AID1372447	Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 to 5 hrs after test compound dosing measured for 3 mins in presence of opioid receptor ant	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID1372448	Expectorant activity in ICR mouse assessed as increase in phenol red secretion in trachea at 50 mg/kg, po for 3 days followed by phenol red treatment at 30 mins post last dose measured after 30 mins by UV-Vis spectrophotometric assay relative to control	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID378532	Cytotoxicity against human CEM cells after 72 hrs by MTT assay	2005	Journal of natural products, Mar, Volume: 68, Issue:3	Cytotoxic flavonoids from Platymiscium floribundum.
AID339158	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as serum VLDLC level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID1875272	Inhibition of MMP3 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID458820	Inhibition of Spanish flu (A/Bervig_Mission/1/18) neuraminidase	2010	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3	Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.
AID1453619	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 10 uM after 24 hrs by Griess reagent based assay relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID469801	Estrogenic activity in human T47D cells assessed as drug level causing stimulation of cell proliferation equivalent to 100 pM estradiol after 96 hrs by alamar blue assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID378534	Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay	2005	Journal of natural products, Mar, Volume: 68, Issue:3	Cytotoxic flavonoids from Platymiscium floribundum.
AID469805	Estrogenic activity in luciferase transfected human T47D cells assessed as drug level causing stimulation of cell proliferation equivalent to 10 pM estradiol by luciferase reporter gene assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID494421	Cytotoxicity against human K562 cells after 72 hrs by MTT assay	2010	European journal of medicinal chemistry, Aug, Volume: 45, Issue:8	Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.
AID626891	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced TNFalpha secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID626887	Inhibition of Porphyromonas gingivalis ATCC 33277 collagenase assessed at 100 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1372142	Inhibition of recombinant human CYP1A1 expressed in yeast microsomal membranes at 10 uM by fluorescence assay relative to control
AID339161	Antihyperlipidemic activity in Triton-induced hyperlipidemic rat model assessed as serum total cholesterol level at 75 mg/kg, po administered for 2 days through gastric intubation immediately and 20 hrs after triton challenge measured after 4 hrs of last	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID1484045	Antiproliferative activity against human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID404182	Cytotoxicity against human A549 cells after 72 hrs by MTT assay	2008	Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10	Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship.
AID347889	Inhibition of human recombinant PTP1B	2008	Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24	Flavanones from the stem bark of Erythrina abyssinica.
AID775570	Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate at 100 uM	2013	Bioorganic & medicinal chemistry letters, Nov-01, Volume: 23, Issue:21	Evaluation of licorice flavonoids as protein tyrosine phosphatase 1B inhibitors.
AID313354	Cytotoxicity against human PANC1 cells in nutrient deprived medium after 24 hrs	2008	Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1	Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition.
AID626866	Inhibition of Porphyromonas gingivalis ATCC 33277 collagenase assessed as remaining activity at 100 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1809144	Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate incubated for 15 to 20 mins by Ellman's method	2021	Bioorganic & medicinal chemistry letters, 11-15, Volume: 52	Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity.
AID378535	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	2005	Journal of natural products, Mar, Volume: 68, Issue:3	Cytotoxic flavonoids from Platymiscium floribundum.
AID1453614	Growth inhibition of human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID1875271	Inhibition of MMP7 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID1484039	Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM after 6 hrs by ARE-driven luciferase reporter gene assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID1372143	Inhibition of human CYP1B1 expressed in yeast microsomal membranes at 10 uM using 7-ethoxyresorufin as substrate by fluorescence assay relative to control
AID1809146	Antioxidant activity assessed as ABTS radical scavenging activity	2021	Bioorganic & medicinal chemistry letters, 11-15, Volume: 52	Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity.
AID1372445	Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 hr after test compound dosing measured for 3 mins in presence of 5-HT receptor antagonist	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID1484046	Antiproliferative activity against human A549 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID494423	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	2010	European journal of medicinal chemistry, Aug, Volume: 45, Issue:8	Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.
AID1073038	Antiviral activity against Influenza A virus (A/Hong Kong/1/1968(H3N2)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect at 50 uM after 48 hrs	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID469799	Estrogenic activity in human T47D cells assessed as drug level causing stimulation of cell proliferation equivalent to 10 pM estradiol after 96 hrs by alamar blue assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID626888	Inhibition of human MMP9 assessed as remaining activity at 5 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID469806	Estrogenic activity in luciferase transfected human T47D cells assessed as drug level causing stimulation of cell proliferation equivalent to 100 pM estradiol by luciferase reporter gene assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID1410197	Cytotoxicity against human Ishikawa cells assessed as cell death	2018	Journal of natural products, 04-27, Volume: 81, Issue:4	Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.
AID469802	Estrogenic activity in human MCF7 cells assessed as drug level causing stimulation of cell proliferation equivalent to 10 pM estradiol after 96 hrs by alamar blue assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID494425	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	2010	European journal of medicinal chemistry, Aug, Volume: 45, Issue:8	Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.
AID626894	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced IL1-beta secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1875274	Inhibition of MMP1 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID419369	Antioxidant activity assessed as DPPH radical scavenging activity at 200 ug after 30 mins by UV-visible spectrophotometry	2009	European journal of medicinal chemistry, May, Volume: 44, Issue:5	Synthesis of (+/-)Abyssinone I and related compounds: Their anti-oxidant and cytotoxic activities.
AID626889	Inhibition of human MMP9 assessed as remaining activity at 25 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1484040	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production at 10 uM after 24 hrs by Griess assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID1372438	Antitussive activity in po dosed ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency treated with ammonia 1 hr before and 1 to 5 hrs after test compound dosing measured for 3 mins	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID1372449	Expectorant activity in ICR mouse assessed as phenol red secretion in trachea at 20 to 50 mg/kg, po for 3 days followed by phenol red treatment at 30 mins post last dose measured after 30 mins by UV-Vis spectrophotometric assay relative to control	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID626903	Cytotoxicity against human U937 cells assessed as loss of cell viability by MTT assay	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID338974	Inhibition of cow milk xanthine oxidase at 50 ug/mL
AID338975	Inhibition of cow milk xanthine oxidase
AID1649932	Inhibition of YES (unknown origin)	2019	European journal of medicinal chemistry, Mar-15, Volume: 166	Pharmacological urate-lowering approaches in chronic kidney disease.
AID1484037	Inhibition of recombinant human PTP1B using pNPP as substrate at 10 uM after 30 mins relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID339159	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as ratio of HDLC to serum total cholesterol level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID626890	Inhibition of human MMP9 assessed as remaining activity at 100 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID447165	Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 mins	2009	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 19, Issue:17	Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B.
AID1484047	Antiproliferative activity against human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID494424	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	2010	European journal of medicinal chemistry, Aug, Volume: 45, Issue:8	Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.
AID1484034	Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate at 10 uM preincubated for 15 mins followed by substrate addition relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID626892	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced CCL5 secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID379219	Inhibition of human recombinant PTP1B	2006	Journal of natural products, Nov, Volume: 69, Issue:11	Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii.
AID419368	Antioxidant activity assessed as ferric ion reducing activity at 200 ug after 20 mins by UV-visible spectrophotometry	2009	European journal of medicinal chemistry, May, Volume: 44, Issue:5	Synthesis of (+/-)Abyssinone I and related compounds: Their anti-oxidant and cytotoxic activities.
AID458821	Inhibition of Spanish flu (A/Bervig_Mission/1/18) neuraminidase by noncompetitive inhibition assay	2010	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3	Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.
AID1463920	Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM incubated for 6 hrs by ARE-driven luciferase reporter gene assay relative to untreated control	2017	Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20	Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl
AID385354	Cytotoxicity against rat H4IIE cells after 24 hrs by MTT assay	2008	Journal of natural products, Apr, Volume: 71, Issue:4	Prenylated flavonoid derivatives from the bark of Erythrina addisoniae.
AID1875270	Inhibition of MMP9 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID1484042	Inhibition of LPS-induced NF-kappaB (unknown origin) transactivation expressed in human SW480 cells at 10 uM administered 1 hr after LPS stimulation measured after 6 hrs by luciferase reporter gene assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID1809143	Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 to 20 mins by Ellman's method	2021	Bioorganic & medicinal chemistry letters, 11-15, Volume: 52	Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity.
AID469804	Estrogenic activity in luciferase transfected human MCF7 cells assessed as drug level causing stimulation of cell proliferation equivalent to 100 pM estradiol by luciferase reporter gene assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID321165	Inhibition of human aromatase in placental microsomes relative to aminogluthetimide	2008	Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3	New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation.
AID1073037	Cytotoxicity against MDCK cells after 72 hrs	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID1410198	Cytotoxicity against human MDA-MB-231/beta41 cells assessed as cell death	2018	Journal of natural products, 04-27, Volume: 81, Issue:4	Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.
AID1809145	Selectivity index, ratio of IC50 for equine serum BuChE using butyrylthiocholine chloride as substrate to IC50 for electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 to 20 mins by Ellman's method	2021	Bioorganic & medicinal chemistry letters, 11-15, Volume: 52	Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity.
AID378536	Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay	2005	Journal of natural products, Mar, Volume: 68, Issue:3	Cytotoxic flavonoids from Platymiscium floribundum.
AID1073042	Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assay	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID339154	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as serum total cholesterol level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID339160	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as atherogenic index at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID422533	Cytotoxicity against NHEM cells assessed as cell viability 24 hrs by WST-8 assay	2009	Journal of natural products, Jan, Volume: 72, Issue:1	Melanin synthesis inhibitors from Lespedeza cyrtobotrya.
AID1633148	Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as substrate preincubated for 10 mins and measured by fluorescence based method	2019	European journal of medicinal chemistry, Apr-01, Volume: 167	Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.
AID469800	Estrogenic activity in human MCF7 cells assessed as drug level causing stimulation of cell proliferation equivalent to 100 pM estradiol after 96 hrs by alamar blue assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID626864	Inhibition of Porphyromonas gingivalis ATCC 33277 collagenase assessed as remaining activity at 5 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1855801	Agonist activity at ER-beta (unknown origin)	2022	European journal of medicinal chemistry, Nov-05, Volume: 241	An overview on Estrogen receptors signaling and its ligands in breast cancer.
AID469803	Estrogenic activity in luciferase transfected human MCF7 cells assessed as drug level causing stimulation of cell proliferation equivalent to 10 pM estradiol by luciferase reporter gene assay	2009	Journal of natural products, Dec, Volume: 72, Issue:12	Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
AID1372435	Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 5 hrs after test compound dosing measured for 3 mins relative to control	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID1372437	Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 to 5 hrs after test compound dosing measured for 3 mins relative to control	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID1453621	Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human SW480 cells at 10 uM by luciferase reporter gene assay	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID1484048	Antiproliferative activity against human SW480 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Journal of natural products, 02-24, Volume: 80, Issue:2	Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
AID339157	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as serum LDLC level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID1453616	Growth inhibition of human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID1453615	Growth inhibition of human SW480 cells at 10 uM after 24 hrs by MTS assay relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID1410191	Estrogenic activity at ERalpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-nitrophenol as substrate treated for 96 hrs followed by substrate addition by spectrophotometric method	2018	Journal of natural products, 04-27, Volume: 81, Issue:4	Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.
AID1372446	Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 hr after test compound dosing measured for 3 mins in presence of ATP-sensitive K+ channel	2018	Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1	Antitussive and expectorant activities of licorice and its major compounds.
AID339163	Antihyperlipidemic activity in Triton-induced hyperlipidemic rat model assessed as serum total lipid level at 75 mg/kg, po administered for 2 days through gastric intubation immediately and 20 hrs after triton challenge measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID321164	Inhibition of human aromatase in placental microsomes	2008	Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3	New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation.
AID1410193	Estrogenic activity at ERbeta (unknown origin) expressed in human MDA-MB-231/beta41 cells after 18 hrs by renilla luciferase reporter gene assay	2018	Journal of natural products, 04-27, Volume: 81, Issue:4	Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.
AID626895	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced IL8 secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID626952	Antibacterial activity against Prevotella intermedia ATCC 25611 by microdilution technique in presence of 1% fetal bovine serum	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1073045	Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assay	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID1301467	Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate at 25 uM after 30 mins relative to control	2016	Journal of natural products, Feb-26, Volume: 79, Issue:2	Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
AID626904	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced MMP9 secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID419370	Cytotoxicity against human MCF7 cells at 25 to 150 uM after 72 hrs by MTT assay	2009	European journal of medicinal chemistry, May, Volume: 44, Issue:5	Synthesis of (+/-)Abyssinone I and related compounds: Their anti-oxidant and cytotoxic activities.
AID626893	Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced of IL6 secretion at 5 ug/ml after 24 hrs by ELISA relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1875273	Inhibition of MMP2 in human U2OS cells at 5 umol/L by peptide microarray-based fluorescence assay	2022	Journal of natural products, 10-28, Volume: 85, Issue:10	Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.
AID1073044	Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assay	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID1334868	Inhibition of LPS-stimulated nitric oxide production in ddy mouse peritoneal macrophages measured after 20 hrs by Greiss method	2017	Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2	Structure-activity relationship of the inhibitory effects of flavonoids on nitric oxide production in RAW264.7 cells.
AID626906	Inhibition of LPS-induced AP-1 activation in human U937 cells at 5 ug/ml after 1 hr relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID626865	Inhibition of Porphyromonas gingivalis ATCC 33277 collagenase assessed as remaining activity at 25 ug/ml after 4 hrs by fluorimetric analysis relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID1073039	Antiviral activity against Influenza A virus J/8178/09 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect at 50 uM after 48 hrs	2014	Journal of natural products, Mar-28, Volume: 77, Issue:3	Computer-guided approach to access the anti-influenza activity of licorice constituents.
AID1453623	Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate at 10 uM after 30 mins relative to control	2017	Bioorganic & medicinal chemistry, 07-15, Volume: 25, Issue:14	Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
AID339162	Antihyperlipidemic activity in Triton-induced hyperlipidemic rat model assessed as serum triglyceride level at 75 mg/kg, po administered for 2 days through gastric intubation immediately and 20 hrs after triton challenge measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID626905	Inhibition of LPS-induced NF-kappaB p65 activation in human U937 cells at 5 ug/ml after 1 hr relative to control	2011	Journal of natural products, Sep-23, Volume: 74, Issue:9	Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential.
AID339155	Antihyperlipidemic activity in diet-induced hyperlipidemic rat model assessed as serum triglyceride level at 40 mg/kg, po administered once daily in morning through gastric intubation for 14 days measured after 4 hrs of last dose	1993	Journal of natural products, Jul, Volume: 56, Issue:7	Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium.
AID1347159	Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347160	Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346880	Human Estrogen receptor-beta (3A. Estrogen receptors)	2008	Molecular and cellular endocrinology, Feb-13, Volume: 283, Issue:1-2	Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	5 (2.42)	18.2507
2000's	43 (20.77)	29.6817
2010's	126 (60.87)	24.3611
2020's	33 (15.94)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	6 (2.84%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	205 (97.16%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
flavone	[no description available]	medium	1	flavones	metabolite; nematicide
quercetin pentaacetate	[no description available]	medium	1
sakuranetin	[no description available]	medium	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; flavonoid phytoalexin; monomethoxyflavanone	antimycobacterial drug; plant metabolite
prunin protein, prunus	[no description available]	medium	2	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; flavanone 7-O-beta-D-glucoside; monosaccharide derivative	antibacterial agent; antilipemic drug; hypoglycemic agent; metabolite
daidzin	[no description available]	medium	3	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative	plant metabolite
homoorientin	[no description available]	medium	1	flavone C-glycoside; tetrahydroxyflavone	antineoplastic agent; radical scavenger
astilbin	[no description available]	medium	1	3'-hydroxyflavanones; 4'-hydroxyflavanones; alpha-L-rhamnoside; flavanone glycoside; monosaccharide derivative; tetrahydroxyflavanone	anti-inflammatory agent; plant metabolite; radical scavenger
aromadedrin	[no description available]	medium	2	4'-hydroxyflavanones; dihydroflavonols; secondary alpha-hydroxy ketone; tetrahydroxyflavanone	metabolite
swertisin	[no description available]	medium	1	dihydroxyflavone; flavone C-glycoside; monomethoxyflavone; monosaccharide derivative; polyphenol	adenosine A1 receptor antagonist; anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite
cirsimarin	[no description available]	medium	1	flavonoids; glycoside
cirsiliol	[no description available]	medium	1	dimethoxyflavone; trihydroxyflavone	plant metabolite
isosakuranetin	[no description available]	medium	3	(2S)-flavan-4-one; 4'-methoxyflavanones; dihydroxyflavanone; monomethoxyflavanone	plant metabolite
cirsilineol	[no description available]	medium	1	dihydroxyflavone; trimethoxyflavone	antineoplastic agent; plant metabolite
pectolinarin	[no description available]	medium	1	dimethoxyflavone; disaccharide derivative; glycosyloxyflavone; monohydroxyflavanone; rutinoside	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; plant metabolite
irisflorentin	[no description available]	medium	1	4'-methoxyisoflavones
scutellarin	[no description available]	medium	2	glucosiduronic acid; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antineoplastic agent; proteasome inhibitor
cirsimaritin	[no description available]	medium	1	dihydroxyflavone; dimethoxyflavone
phellamurin	[no description available]	medium	1	4'-hydroxyflavanones; beta-D-glucoside; dihydroflavonols; flavanone glycoside; monosaccharide derivative; trihydroxyflavanone	metabolite
taxifolin	[no description available]	medium	1	taxifolin	metabolite
eriodictyol	[no description available]	medium	3	3'-hydroxyflavanones; tetrahydroxyflavanone
5,6,7-trimethoxyflavone	[no description available]	medium	1	trimethoxyflavone	anti-HSV-1 agent; plant metabolite
likviriton	[no description available]	medium	29	beta-D-glucoside; flavanone glycoside; monohydroxyflavanone; monosaccharide derivative	anti-inflammatory agent; anticoronaviral agent; plant metabolite
quercetin 3-o-glucuronide	[no description available]	medium	1	beta-D-glucosiduronic acid; quercetin O-glycoside	antidepressant; antioxidant; metabolite
formononetin	[no description available]	medium	16	4'-methoxyisoflavones; 7-hydroxyisoflavones	phytoestrogen; plant metabolite
vitexin	[no description available]	medium	2	C-glycosyl compound; trihydroxyflavone	antineoplastic agent; EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite; platelet aggregation inhibitor
acacetin	[no description available]	medium	2	dihydroxyflavone; monomethoxyflavone	anticonvulsant; plant metabolite
luteolin-7-glucoside	[no description available]	medium	1	beta-D-glucoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antioxidant; plant metabolite
chrysoeriol	[no description available]	medium	1	monomethoxyflavone; trihydroxyflavone	antineoplastic agent; antioxidant; metabolite
quercetin 3-o-methyl ether	[no description available]	medium	1	monomethoxyflavone; tetrahydroxyflavone	antimicrobial agent; metabolite
apigetrin	[no description available]	medium	2	beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative	antibacterial agent; metabolite; non-steroidal anti-inflammatory drug
genistein	[no description available]	medium	17	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
genistin	[no description available]	medium	1	7-hydroxyisoflavones 7-O-beta-D-glucoside
amentoflavone	[no description available]	medium	1	biflavonoid; hydroxyflavone; ring assembly	angiogenesis inhibitor; antiviral agent; cathepsin B inhibitor; P450 inhibitor; plant metabolite
baicalein	[no description available]	medium	2	trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; ferroptosis inhibitor; geroprotector; hormone antagonist; plant metabolite; prostaglandin antagonist; radical scavenger
diosmin	[no description available]	medium	1	dihydroxyflavanone; disaccharide derivative; glycosyloxyflavone; monomethoxyflavone; rutinoside	anti-inflammatory agent; antioxidant
hyperoside	[no description available]	medium	1	beta-D-galactoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	hepatoprotective agent; plant metabolite
3-methylquercetin	[no description available]	medium	1	7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone	anticoagulant; EC 1.14.18.1 (tyrosinase) inhibitor; metabolite
orientin	[no description available]	medium	1	3'-hydroxyflavonoid; C-glycosyl compound; tetrahydroxyflavone	antioxidant; metabolite
robinetin	[no description available]	medium	2	7-hydroxyflavonol; pentahydroxyflavone	plant metabolite
sciadopitysin	[no description available]	medium	1	biflavonoid; hydroxyflavone; methoxyflavone; ring assembly	bone density conservation agent; platelet aggregation inhibitor
scutellarein	[no description available]	medium	1	tetrahydroxyflavone	metabolite
wogonin	[no description available]	medium	1	dihydroxyflavone; monomethoxyflavone	angiogenesis inhibitor; antineoplastic agent; cyclooxygenase 2 inhibitor; plant metabolite
daidzein	[no description available]	medium	11	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite
iridin	[no description available]	medium	1	4'-methoxyisoflavones; 7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative	plant metabolite
tectoridin	[no description available]	medium	1	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; methoxyisoflavone; monosaccharide derivative	plant metabolite
tectorigenin	[no description available]	medium	2	7-hydroxyisoflavones; methoxyisoflavone	anti-inflammatory agent; plant metabolite
kaempferol-3-o-galactoside	[no description available]	medium	1	beta-D-galactoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antifungal agent; plant metabolite
rhoifolin	[no description available]	medium	1	dihydroxyflavone; glycosyloxyflavone; neohesperidoside	metabolite
veronicastroside	[no description available]	medium	1	disaccharide derivative; glycosyloxyflavone; neohesperidoside; trihydroxyflavone	antibacterial agent; metabolite
quercimeritrin	[no description available]	medium	1	beta-D-glucoside; flavonols; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antioxidant; metabolite
linarin	[no description available]	medium	1
fustin	[no description available]	medium	1
juglanin	[no description available]	medium	1	flavonoids; glycoside
5,7-dihydroxy-4',6-dimethoxyflavone	[no description available]	medium	1	dihydroxyflavone; dimethoxyflavone	plant metabolite
sophoricoside	[no description available]	medium	1	acrovestone; isoflavonoid
tilianin	[no description available]	medium	1
4',5,7-trihydroxy-3,6-dimethoxyflavone	[no description available]	medium	1
irigenin	[no description available]	medium	1	4'-methoxyisoflavones; hydroxyisoflavone	plant metabolite
narcissin flavonol	[no description available]	medium	1	disaccharide derivative; glycosyloxyflavone; monomethoxyflavone; trihydroxyflavone
lespenefril	[no description available]	medium	1	alpha-L-rhamnoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative; polyphenol	anti-inflammatory agent; antidepressant; antineoplastic agent; apoptosis inducer; bone density conservation agent; hypoglycemic agent; immunomodulator; plant metabolite
avicularin	[no description available]	medium	1	alpha-L-arabinofuranoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	hepatoprotective agent; plant metabolite
kaempferol 7-o-glucoside	[no description available]	medium	1	beta-D-glucoside; flavonols; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone	metabolite; plant metabolite; radical scavenger
Diosmetin 7-O-beta-D-glucopyranoside	[no description available]	medium	1	flavonoids; glycoside
marsupsin	[no description available]	medium	1	1-benzofurans; aromatic ether; polyphenol	antilipemic drug; hypoglycemic agent; metabolite
homopterocarpin	[no description available]	medium	1	pterocarpans
ursolic acid	[no description available]	medium	7	hydroxy monocarboxylic acid; pentacyclic triterpenoid	geroprotector; plant metabolite
abyssinone v	[no description available]	medium	3	4'-hydroxyflavanones; phenols; trihydroxyflavanone	metabolite
naringin	[no description available]	medium	3	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; neohesperidoside	anti-inflammatory agent; antineoplastic agent; metabolite
isoliquiritigenin	[no description available]	medium	44	chalcones	antineoplastic agent; biological pigment; EC 1.14.18.1 (tyrosinase) inhibitor; GABA modulator; geroprotector; metabolite; NMDA receptor antagonist
alpinumisoflavone	[no description available]	medium	3	isoflavanones	metabolite
rk 682	[no description available]	medium	3
fluorouracil	[no description available]	medium	3	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
paclitaxel	[no description available]	medium	1	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
arctigenin	[no description available]	medium	1	lignan
medicarpin, (6as-cis)-isomer	[no description available]	medium	2	medicarpin
(+)-Eudesmin	[no description available]	medium	2	lignan
naringenin	[no description available]	medium	16	(2S)-flavan-4-one; naringenin	expectorant; plant metabolite
mucronulatol	[no description available]	medium	2	hydroxyisoflavans; methoxyisoflavan	antineoplastic agent; plant metabolite
syringaresinol	[no description available]	medium	2	syringaresinol	antineoplastic agent
(2S)-7-hydroxyflavanone	[no description available]	medium	3	7-hydroxyflavanone
biochanin a	[no description available]	medium	5	4'-methoxyisoflavones; 7-hydroxyisoflavones	antineoplastic agent; EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
7,3'-dihydroxy-4'-methoxyisoflavone	[no description available]	medium	3	4'-methoxyisoflavones; 7-hydroxyisoflavones	antioxidant; metabolite
2'-hydroxyformononetin	[no description available]	medium	4	4'-methoxyisoflavones; 7-hydroxyisoflavones	anti-inflammatory agent
4'-methoxy-3',5,7-trihydroxyisoflavone	[no description available]	medium	3	4'-methoxyisoflavones; 7-hydroxyisoflavones
3-deoxysappanchalcone	[no description available]	medium	3	chalcones; monomethoxybenzene; phenols	metabolite
2',4'-dihydroxychalcone	[no description available]	medium	2
(-)-pinoresinol	[no description available]	medium	2	pinoresinol	plant metabolite
7-hydroxyflavanone	[no description available]	medium	1	monohydroxyflavanone
flavanone	[no description available]	medium	3	flavanones
alpha-naphthoflavone	[no description available]	medium	2	extended flavonoid; naphtho-gamma-pyrone; organic heterotricyclic compound	aryl hydrocarbon receptor agonist; aryl hydrocarbon receptor antagonist; EC 1.14.14.14 (aromatase) inhibitor
abyssinone ii	[no description available]	medium	1
Kanzonol B	[no description available]	medium	5	chalcones
ketoconazole	[no description available]	medium	1	dichlorobenzene; dioxolane; ether; imidazoles; N-acylpiperazine; N-arylpiperazine
apigenin	[no description available]	medium	5	trihydroxyflavone	antineoplastic agent; metabolite
gossypetin	[no description available]	medium	1	7-hydroxyflavonol; hexahydroxyflavone	plant metabolite
galangin	[no description available]	medium	1	7-hydroxyflavonol; trihydroxyflavone	antimicrobial agent; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; plant metabolite
myricetin	[no description available]	medium	3	7-hydroxyflavonol; hexahydroxyflavone	antineoplastic agent; antioxidant; cyclooxygenase 1 inhibitor; food component; geroprotector; hypoglycemic agent; plant metabolite
hydroquinone	[no description available]	medium	1	benzenediol; hydroquinones	antioxidant; carcinogenic agent; cofactor; Escherichia coli metabolite; human xenobiotic metabolite; mouse metabolite; skin lightening agent
phaseollidin	[no description available]	medium	1	pterocarpans
isobavachin	[no description available]	medium	2	flavanones
arbutin	[no description available]	medium	1	beta-D-glucoside; monosaccharide derivative	Escherichia coli metabolite; plant metabolite
xanthoangelol	[no description available]	medium	1
leachianone g	[no description available]	medium	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; tetrahydroxyflavanone
isobavachalcone	[no description available]	medium	5	chalcones; polyphenol	antibacterial agent; metabolite; platelet aggregation inhibitor
neobavaisoflavone	[no description available]	medium	1	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; plant metabolite; platelet aggregation inhibitor
bavachin	[no description available]	medium	1
licochalcone a	[no description available]	medium	7	chalcones
licochalcone c	[no description available]	medium	4
pinocembrin	[no description available]	medium	2	(2S)-flavan-4-one; dihydroxyflavanone	antineoplastic agent; antioxidant; metabolite; neuroprotective agent; vasodilator agent
pinobanksin	[no description available]	medium	1	secondary alpha-hydroxy ketone; trihydroxyflavanone	antimutagen; antioxidant; metabolite
7,4'-dihydroxy-3'-methoxyisoflavone	[no description available]	medium	2	7-hydroxyisoflavones; methoxyisoflavone	antiplasmodial drug; metabolite
oseltamivir	[no description available]	medium	2	acetamides; amino acid ester; cyclohexenecarboxylate ester; primary amino compound	antiviral drug; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; environmental contaminant; prodrug; xenobiotic
gu 7	[no description available]	medium	1	isoflavonoid; organic hydroxy compound
ononin	[no description available]	medium	2	4'-methoxyisoflavones; 7-hydroxyisoflavones 7-O-beta-D-glucoside; monosaccharide derivative	plant metabolite
glycyrin	[no description available]	medium	2	aromatic ether; coumarins; hydroxyisoflavans	antibacterial agent; metabolite; plant metabolite
glyasperin D	[no description available]	medium	2	aromatic ether; hydroxyisoflavans; methoxyisoflavan	plant metabolite
licocoumarone	[no description available]	medium	2	1-benzofurans; aromatic ether; resorcinols	antibacterial agent; apoptosis inducer; EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
Kumatakenin	[no description available]	medium	1	ether; flavonoids
neoglycyrol	[no description available]	medium	2	aromatic ether; coumestans; delta-lactone; polyphenol	antineoplastic agent; plant metabolite
glabridin	[no description available]	medium	7	hydroxyisoflavans	antiplasmodial drug
vicenin ii	[no description available]	medium	1	C-glycosyl compound; trihydroxyflavone	metabolite
Euchrestaflavanone A	[no description available]	medium	3	flavanones
isoschaftoside	[no description available]	medium	1	C-glycosyl compound; trihydroxyflavone	metabolite
quercetin 3-o-glucopyranoside	[no description available]	medium	1	beta-D-glucoside; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antineoplastic agent; antioxidant; antipruritic drug; bone density conservation agent; geroprotector; histamine antagonist; osteogenesis regulator; plant metabolite
7-hydroxy-6,4'-dimethoxyisoflavone	[no description available]	medium	2	4'-methoxyisoflavones; 7-hydroxyisoflavones	plant metabolite
4',7-dihydroxyflavone	[no description available]	medium	5	dihydroxyflavone	metabolite
astragalin	[no description available]	medium	1	beta-D-glucoside; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone	plant metabolite; trypanocidal drug
eurycarpin b	[no description available]	medium	5	isoflavonoid
licochalcone b	[no description available]	medium	3	chalcones
4-hydroxylonchocarpin	[no description available]	medium	1
glabrol	[no description available]	medium	5	flavanones
odoratin	[no description available]	medium	1
honokiol	[no description available]	medium	1	biphenyls
Licoflavone B	[no description available]	medium	3	flavones
galantamine	[no description available]	medium	1	benzazepine alkaloid fundamental parent; benzazepine alkaloid; organic heterotetracyclic compound; tertiary amino compound	antidote to curare poisoning; cholinergic drug; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant metabolite
glycyrrhizic acid	[no description available]	medium	23	enone; glucosiduronic acid; pentacyclic triterpenoid; tricarboxylic acid; triterpenoid saponin	EC 3.4.21.5 (thrombin) inhibitor; plant metabolite
2-tert-butylhydroquinone	[no description available]	medium	2	hydroquinones	food antioxidant
irinotecan	[no description available]	medium	2	carbamate ester; delta-lactone; N-acylpiperidine; pyranoindolizinoquinoline; ring assembly; tertiary alcohol; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 5.99.1.2 (DNA topoisomerase) inhibitor; prodrug
gliclazide	[no description available]	medium	1
tamiflu	[no description available]	medium	1	phosphate salt
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	[no description available]	medium	3	amino aldehyde; carbamate ester; tripeptide	proteasome inhibitor
gancaonin I	[no description available]	medium	1	1-benzofurans; aromatic ether; resorcinols	antibacterial agent; plant metabolite
6,8-diprenylgenistein	[no description available]	medium	3	7-hydroxyisoflavones	antibacterial agent; plant metabolite
licoricidin	[no description available]	medium	1	aromatic ether; hydroxyisoflavans; methoxyisoflavan	antibacterial agent; plant metabolite
curcumin	[no description available]	medium	4	aromatic ether; beta-diketone; diarylheptanoid; enone; polyphenol	anti-inflammatory agent; antifungal agent; antineoplastic agent; biological pigment; contraceptive drug; dye; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; flavouring agent; food colouring; geroprotector; hepatoprotective agent; immunomodulator; iron chelator; ligand; lipoxygenase inhibitor; metabolite; neuroprotective agent; nutraceutical; radical scavenger
kaempferol	[no description available]	medium	4	7-hydroxyflavonol; flavonols; tetrahydroxyflavone	antibacterial agent; geroprotector; human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; plant metabolite
glycycoumarin	[no description available]	medium	3	aromatic ether; coumarins; resorcinols	antispasmodic drug; plant metabolite
Isolicoflavonol	[no description available]	medium	1	flavones
Licoflavone A	[no description available]	medium	4	flavones
3-o-methylbutein	[no description available]	medium	1	chalcones
isoangustone a	[no description available]	medium	2	isoflavanones
quercetin	[no description available]	medium	4	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger
luteolin	[no description available]	medium	4	3'-hydroxyflavonoid; tetrahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist
diosmetin	[no description available]	medium	1	3'-hydroxyflavonoid; monomethoxyflavone; trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; bone density conservation agent; cardioprotective agent; plant metabolite; tropomyosin-related kinase B receptor agonist; vasodilator agent
tamarixetin	[no description available]	medium	1	7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone	antioxidant; metabolite
tricin	[no description available]	medium	1	3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite
3',4',7-trihydroxyflavone	[no description available]	medium	1	flavones
etoposide	[no description available]	medium	1	beta-D-glucoside; furonaphthodioxole; organic heterotetracyclic compound	antineoplastic agent; DNA synthesis inhibitor
abyssinone i	[no description available]	medium	1	monohydroxyflavanone; phenols	apoptosis inhibitor; plant metabolite
glabrene	[no description available]	medium	1	isoflavonoid
lupiwighteone	[no description available]	medium	2	isoflavones
derrone	[no description available]	medium	1	isoflavonoid
licoisoflavone a	[no description available]	medium	2	7-hydroxyisoflavones	metabolite
wighteone	[no description available]	medium	2	7-hydroxyisoflavones	antifungal agent; plant metabolite
3',4',7-trihydroxyisoflavone	[no description available]	medium	1	7-hydroxyisoflavones	antineoplastic agent; EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor; metabolite
licoisoflavone b	[no description available]	medium	2
semilicoisoflavone b	[no description available]	medium	2	7-hydroxyisoflavones	EC 1.1.1.21 (aldehyde reductase) inhibitor; plant metabolite
licoflavone c	[no description available]	medium	3
licochalcone e	[no description available]	medium	2
licochalcone d	[no description available]	medium	1
11-deoxy glycyrrhetinic acid	[no description available]	medium	1	triterpenoid
glycyrrhetinic acid	[no description available]	medium	2	cyclic terpene ketone; hydroxy monocarboxylic acid; pentacyclic triterpenoid	immunomodulator; plant metabolite
guaifenesin	[no description available]	medium	1	methoxybenzenes
carbetapentane citrate	[no description available]	medium	1	carbonyl compound
2,3-bis(4-hydroxyphenyl)-propionitrile	[no description available]	medium	2	nitrile; phenols	estrogen receptor agonist
8-prenylnaringenin	[no description available]	medium	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; trihydroxyflavanone	plant metabolite; platelet aggregation inhibitor
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole	[no description available]	medium	1	phenols; pyrazoles	estrogen receptor agonist
benzbromarone	[no description available]	medium	1	1-benzofurans; aromatic ketone	uricosuric drug
probenecid	[no description available]	medium	1	benzoic acids; sulfonamide	uricosuric drug
febuxostat	[no description available]	medium	1	1,3-thiazolemonocarboxylic acid; aromatic ether; nitrile	EC 1.17.3.2 (xanthine oxidase) inhibitor
merbarone	[no description available]	medium	1
morin	[no description available]	medium	1	7-hydroxyflavonol; pentahydroxyflavone	angiogenesis modulating agent; anti-inflammatory agent; antibacterial agent; antihypertensive agent; antineoplastic agent; antioxidant; EC 5.99.1.2 (DNA topoisomerase) inhibitor; hepatoprotective agent; metabolite; neuroprotective agent
topiroxostat	[no description available]	medium	1
arhalofenate	[no description available]	medium	1
lesinurad	[no description available]	medium	1	aryl sulfide; cyclopropanes; monocarboxylic acid; naphthalenes; organobromine compound; triazoles	uricosuric drug
allopurinol	[no description available]	medium	2	nucleobase analogue; organic heterobicyclic compound	antimetabolite; EC 1.17.3.2 (xanthine oxidase) inhibitor; gout suppressant; radical scavenger
ulodesine	[no description available]	medium	1
gallic acid	[no description available]	medium	1	trihydroxybenzoic acid	antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite
emodin	[no description available]	medium	1	trihydroxyanthraquinone	antineoplastic agent; laxative; plant metabolite; tyrosine kinase inhibitor
epigallocatechin gallate	[no description available]	medium	1	flavans; gallate ester; polyphenol	antineoplastic agent; antioxidant; apoptosis inducer; geroprotector; Hsp90 inhibitor; neuroprotective agent; plant metabolite
gallocatechol	[no description available]	medium	1	catechin; flavan-3,3',4',5,5',7-hexol	antioxidant; food component; plant metabolite
epicatechin gallate	[no description available]	medium	1	catechin; gallate ester; polyphenol	EC 3.2.1.1 (alpha-amylase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; metabolite
(-)-gallocatechin gallate	[no description available]	medium	1	catechin; gallate ester; polyphenol	antineoplastic agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; human xenobiotic metabolite; plant metabolite
medicarpin	[no description available]	medium	5	medicarpin	plant metabolite
chrysin	[no description available]	medium	1	7-hydroxyflavonol; dihydroxyflavone	anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite
broussonin b	[no description available]	medium	1
(-)-catechin-3-O-gallate	[no description available]	medium	1	flavans; gallate ester; polyphenol	metabolite
donepezil	[no description available]	medium	1	aromatic ether; indanones; piperidines; racemate	EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; nootropic agent
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	[no description available]	medium	1	chromanol; monocarboxylic acid; phenols	antioxidant; ferroptosis inhibitor; neuroprotective agent; radical scavenger; Wnt signalling inhibitor
aminoglutethimide	[no description available]	medium	2	dicarboximide; piperidones; substituted aniline	adrenergic agent; anticonvulsant; antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
anastrozole	[no description available]	medium	1	nitrile; triazoles	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
letrozole	[no description available]	medium	1	nitrile; triazoles	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
formestane	[no description available]	medium	1	17-oxo steroid; 3-oxo-Delta(4) steroid; enol; hydroxy steroid	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
fadrozole	[no description available]	medium	1	imidazopyridine
aromasil	[no description available]	medium	1	17-oxo steroid; 3-oxo-Delta(1),Delta(4)-steroid	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor; environmental contaminant; xenobiotic
equol	[no description available]	medium	2	hydroxyisoflavans
fulvestrant	[no description available]	medium	2	17beta-hydroxy steroid; 3-hydroxy steroid; organofluorine compound; sulfoxide	antineoplastic agent; estrogen antagonist; estrogen receptor antagonist
7-((4'-aminophenyl)thio)-1,4-androstadiene-3,17-dione	[no description available]	medium	1
irosustat	[no description available]	medium	1
marimastat	[no description available]	medium	1	hydroxamic acid; secondary carboxamide	antineoplastic agent; matrix metalloproteinase inhibitor
sinensetin	[no description available]	medium	1	pentamethoxyflavone	plant metabolite
mangiferin	[no description available]	medium	1	C-glycosyl compound; xanthones	anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite
arsenic trioxide	[no description available]	medium	1
ro 48-8071	[no description available]	medium	1	aromatic ether; aromatic ketone; bromobenzenes; monofluorobenzenes; olefinic compound; tertiary amino compound	antineoplastic agent; EC 5.4.99.7 (lanosterol synthase) inhibitor
chloroquine	[no description available]	medium	1	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
4-methylimidazole	[no description available]	medium	1	imidazoles	carcinogenic agent; reaction intermediate
lysine	[no description available]	medium	1	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
pyruvaldehyde	[no description available]	medium	2	2-oxo aldehyde; propanals	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
5-hydroxymethylfurfural	[no description available]	medium	1	arenecarbaldehyde; furans; primary alcohol	indicator; Maillard reaction product
glucose, (beta-d)-isomer	[no description available]	medium	31	D-glucopyranose	epitope; mouse metabolite
monocrotaline	[no description available]	medium	2	pyrrolizidine alkaloid
carbon tetrachloride	[no description available]	medium	3	chlorocarbon; chloromethanes	hepatotoxic agent; refrigerant
hydroxyproline	[no description available]	medium	1	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite
guttiferone e	[no description available]	medium	1
oleanolic acid	[no description available]	medium	2	hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
vestitol	[no description available]	medium	1	aromatic ether; hydroxyisoflavans; methoxyisoflavan	anti-inflammatory agent; phytoalexin; plant metabolite
beta-amyrin	[no description available]	medium	1	pentacyclic triterpenoid; secondary alcohol	Aspergillus metabolite; plant metabolite
glutinol	[no description available]	medium	1	pentacyclic triterpenoid; secondary alcohol
warfarin	[no description available]	medium	3	benzenes; hydroxycoumarin; methyl ketone
morroniside	[no description available]	medium	1
schizandrin b	[no description available]	medium	1
schizandrol b	[no description available]	medium	1	tannin
lignans	[no description available]	medium	2
nodakenin	[no description available]	medium	1	furanocoumarin
puerarin	[no description available]	medium	2	C-glycosyl compound; isoflavonoid
decursin	[no description available]	medium	1	coumarins
loganin	[no description available]	medium	1	beta-D-glucoside; cyclopentapyran; enoate ester; iridoid monoterpenoid; methyl ester; monosaccharide derivative; secondary alcohol	anti-inflammatory agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; EC 3.4.23.46 (memapsin 2) inhibitor; neuroprotective agent; plant metabolite
schizandrin	[no description available]	medium	1
glycosides	[no description available]	medium	3
iridoids	[no description available]	medium	1
neoisoliquiritin	[no description available]	medium	7	flavonoids; glycoside
amygdalin	[no description available]	medium	1
sesamin	[no description available]	medium	1	benzodioxoles; furofuran; lignan	antineoplastic agent; neuroprotective agent; plant metabolite
chalcone	[no description available]	medium	15	chalcone	EC 3.2.1.1 (alpha-amylase) inhibitor
chlorogenic acid	[no description available]	medium	2	cinnamate ester; tannin	food component; plant metabolite
3-nitrotyrosine	[no description available]	medium	1	2-nitrophenols; C-nitro compound; nitrotyrosine; non-proteinogenic alpha-amino acid
tyrosine	[no description available]	medium	2	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
erteberel	[no description available]	medium	1
thioflavin t	[no description available]	medium	1	organic chloride salt	fluorochrome; geroprotector; histological dye
1-anilino-8-naphthalenesulfonate	[no description available]	medium	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
angiotensin ii	[no description available]	medium	1	amino acid zwitterion; angiotensin II	human metabolite
isoproterenol	[no description available]	medium	1	catechols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; sympathomimetic agent
trans-4-coumaric acid	[no description available]	medium	1	4-coumaric acid	food component; mouse metabolite; plant metabolite
brucine	[no description available]	medium	1	monoterpenoid indole alkaloid; organic heteroheptacyclic compound
strychnine	[no description available]	medium	1	monoterpenoid indole alkaloid; organic heteroheptacyclic compound	avicide; cholinergic antagonist; glycine receptor antagonist; neurotransmitter agent; rodenticide
androstane-3,17-diol	[no description available]	medium	2	17-hydroxy steroid; 3-hydroxy steroid; androstanoid
oxazoles	[no description available]	medium	2	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
erb 041	[no description available]	medium	2
way 200070	[no description available]	medium	1
beta-escin	[no description available]	medium	1
platycodin d	[no description available]	medium	1	triterpenoid saponin	metabolite
scopolamine hydrobromide	[no description available]	medium	1
citrinin	[no description available]	medium	1
cardamonin	[no description available]	medium	1	chalcones
4'-hydroxychalcone	[no description available]	medium	1	chalcones; phenols	anti-inflammatory agent; antineoplastic agent
kushenin	[no description available]	medium	1
gamma-sitosterol	[no description available]	medium	2	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; phytosterols	marine metabolite; plant metabolite
cytellin	[no description available]	medium	2
neoline	[no description available]	medium	1
songorine	[no description available]	medium	1
aconitine	[no description available]	medium	2
malondialdehyde	[no description available]	medium	1	dialdehyde	biomarker
isotalatizidine	[no description available]	medium	1
gingerol	[no description available]	medium	1	beta-hydroxy ketone; guaiacols	antineoplastic agent; plant metabolite
hesperidin	[no description available]	medium	2	3'-hydroxyflavanones; 4'-methoxyflavanones; dihydroxyflavanone; disaccharide derivative; flavanone glycoside; monomethoxyflavanone; rutinoside	mutagen
hesperetin	[no description available]	medium	1	3'-hydroxyflavanones; 4'-methoxyflavanones; monomethoxyflavanone; trihydroxyflavanone	antineoplastic agent; antioxidant; plant metabolite
sulfamethoxazole	[no description available]	medium	1	isoxazoles; substituted aniline; sulfonamide antibiotic; sulfonamide	antibacterial agent; antiinfective agent; antimicrobial agent; drug allergen; EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; epitope; P450 inhibitor; xenobiotic
ochratoxin a	[no description available]	medium	1	isochromanes; monocarboxylic acid amide; N-acyl-L-phenylalanine; organochlorine compound; phenylalanine derivative	Aspergillus metabolite; calcium channel blocker; carcinogenic agent; mycotoxin; nephrotoxin; Penicillium metabolite; teratogenic agent
albiflorin	[no description available]	medium	3	benzoate ester; beta-D-glucoside; bridged compound; gamma-lactone; monoterpene glycoside; secondary alcohol	neuroprotective agent; plant metabolite
peoniflorin	[no description available]	medium	4
oxypaeoniflora	[no description available]	medium	1	4-hydroxybenzoate ester; beta-D-glucoside; bridged compound; cyclic acetal; lactol; monoterpene glycoside	plant metabolite
dinoprostone	[no description available]	medium	1	prostaglandins E	human metabolite; mouse metabolite; oxytocic
atractylenolide i	[no description available]	medium	1
benzoylmesaconine	[no description available]	medium	1	benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol	analgesic; antiinfective agent; plant metabolite
benzoylhypaconine	[no description available]	medium	1
benzoylaconine	[no description available]	medium	1	benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol	phytotoxin; plant metabolite
e-z cinnamic acid	[no description available]	medium	2	cinnamic acid	plant metabolite
sesquiterpenes	[no description available]	medium	3
atractylenolide iii	[no description available]	medium	1	naphthofuran	metabolite
benzoin	[no description available]	medium	1	benzoins; secondary alpha-hydroxy ketone	EC 3.1.1.1 (carboxylesterase) inhibitor
betadex	[no description available]	medium	1	cyclodextrin
phytoestrogens	[no description available]	medium	2
pinostrobin	[no description available]	medium	1	ether; flavonoids
pregnenolone sulfate	[no description available]	medium	1	steroid sulfate	EC 2.7.1.33 (pantothenate kinase) inhibitor; human metabolite
pregnenolone	[no description available]	medium	1	20-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; C21-steroid	human metabolite; mouse metabolite
glutamic acid	[no description available]	medium	1	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical
antimycin a	[no description available]	medium	1	amidobenzoic acid
cytochrome c-t	[no description available]	medium	3
trinitrobenzenesulfonic acid	[no description available]	medium	1	arenesulfonic acid; C-nitro compound	epitope; explosive; reagent
mesalamine	[no description available]	medium	1	amino acid; aromatic amine; monocarboxylic acid; monohydroxybenzoic acid; phenols	non-steroidal anti-inflammatory drug
temozolomide	[no description available]	medium	1	imidazotetrazine; monocarboxylic acid amide; triazene derivative	alkylating agent; antineoplastic agent; prodrug
dacarbazine	[no description available]	medium	1	dacarbazine
tacrine	[no description available]	medium	1	acridines; aromatic amine	EC 3.1.1.7 (acetylcholinesterase) inhibitor
indomethacin	[no description available]	medium	1	aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole	analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic
deoxycytidine	[no description available]	medium	1	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
gemcitabine	[no description available]	medium	1	organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; environmental contaminant; immunosuppressive agent; photosensitizing agent; prodrug; radiosensitizing agent; xenobiotic
fisetin	[no description available]	medium	2	3'-hydroxyflavonoid; 7-hydroxyflavonol; tetrahydroxyflavone	anti-inflammatory agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; metabolite; plant metabolite
3-hydroxyflavone	[no description available]	medium	2	flavonols; monohydroxyflavone
potassium oxonate	[no description available]	medium	1	organic molecular entity
oxonic acid	[no description available]	medium	1	1,3,5-triazines; monocarboxylic acid
uric acid	[no description available]	medium	1	uric acid	Escherichia coli metabolite; human metabolite; mouse metabolite
D-fructopyranose	[no description available]	medium	1	cyclic hemiketal; D-fructose; fructopyranose	sweetening agent
galactosamine	[no description available]	medium	3	D-galactosamine; primary amino compound	toxin
acetylcysteine	[no description available]	medium	1	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
amyloid beta-peptides	[no description available]	medium	1
uridine diphosphate glucuronic acid	[no description available]	medium	2	UDP-D-glucuronic acid	Escherichia coli metabolite; human metabolite; mouse metabolite
t0901317	[no description available]	medium	1
homoeriodictyol	[no description available]	medium	1	3'-methoxyflavanones; 4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone	flavouring agent; metabolite
psi-baptigenin	[no description available]	medium	1	7-hydroxyisoflavones; benzodioxoles	antiprotozoal drug; plant metabolite
pisatin	[no description available]	medium	1
fucose	[no description available]	medium	1	fucopyranose; L-fucose	Escherichia coli metabolite; mouse metabolite
2-o-methylfucose	[no description available]	medium	1
nitrogenase	[no description available]	medium	1
neohesperidin	[no description available]	medium	1
4-hydroxyphenylacetic acid	[no description available]	medium	1	monocarboxylic acid; phenols	fungal metabolite; human metabolite; mouse metabolite; plant metabolite
sucrose	[no description available]	medium	1	glycosyl glycoside	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; sweetening agent
cadaverine	[no description available]	medium	1	alkane-alpha,omega-diamine	Daphnia magna metabolite; Escherichia coli metabolite; mouse metabolite; plant metabolite
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	[no description available]	medium	1	chromones; morpholines; organochlorine compound	autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector
u 0126	[no description available]	medium	1	aryl sulfide; dinitrile; enamine; substituted aniline	antineoplastic agent; antioxidant; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; osteogenesis regulator; vasoconstrictor agent
pentobarbital	[no description available]	medium	1	barbiturates	GABAA receptor agonist
flumazenil	[no description available]	medium	1	ethyl ester; imidazobenzodiazepine; organofluorine compound	antidote to benzodiazepine poisoning; GABA antagonist
sodium thiosulfate	[no description available]	medium	1	inorganic sodium salt	antidote to cyanide poisoning; antifungal drug; nephroprotective agent
1,1-diphenyl-2-picrylhydrazyl	[no description available]	medium	1
davidigenin	[no description available]	medium	1	dihydrochalcones; polyphenol	anti-allergic agent; anti-asthmatic agent; antioxidant; metabolite
cysteine	[no description available]	medium	1	cysteinium	fundamental metabolite
thiosulfates	[no description available]	medium	1	divalent inorganic anion; sulfur oxide; sulfur oxoanion	human metabolite
hymecromone	[no description available]	medium	1	hydroxycoumarin	antineoplastic agent; hyaluronic acid synthesis inhibitor
dantrolene	[no description available]	medium	1	hydrazone; imidazolidine-2,4-dione	muscle relaxant; neuroprotective agent; ryanodine receptor antagonist
isoliquiritin apioside	[no description available]	medium	1	flavonoids; glycoside
calycosin-7-o-beta-d-glucopyranoside	[no description available]	medium	1	4'-methoxyisoflavones; 7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative
2,7,4'-trihydroxyisoflavanone	[no description available]	medium	2	hydroxyisoflavanone; lactol
3-hydroxyflavanone	[no description available]	medium	1	3'-hydroxyflavanones; monohydroxyflavanone	metabolite
salicylic acid	[no description available]	medium	1	monohydroxybenzoic acid	algal metabolite; antifungal agent; antiinfective agent; EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor; keratolytic drug; plant hormone; plant metabolite
cadmium chloride	[no description available]	medium	1	cadmium coordination entity
europium	[no description available]	medium	1	f-block element atom; lanthanoid atom
vestitone	[no description available]	medium	1	(3R)-2'-hydroxyisoflavanones; hydroxyisoflavanone; methoxyisoflavanone	antibacterial agent; metabolite
butin	[no description available]	medium	1	flavanones
acetaminophen	[no description available]	medium	1	acetamides; phenols	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; cyclooxygenase 3 inhibitor; environmental contaminant; ferroptosis inducer; geroprotector; hepatotoxic agent; human blood serum metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
buthionine sulfoximine	[no description available]	medium	1	diastereoisomeric mixture; homocysteines; non-proteinogenic alpha-amino acid; sulfoximide	EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor; ferroptosis inducer
7-hydroxyflavone	[no description available]	medium	1	hydroxyflavonoid
5,7-dimethoxyflavone	[no description available]	medium	1	dimethoxyflavone	plant metabolite
7-methoxyflavone	[no description available]	medium	1	ether; flavonoids
benzoylpaeoniflorin	[no description available]	medium	1
hexacosanoic acid	[no description available]	medium	1	fatty acid 26:0; straight-chain saturated fatty acid; very long-chain fatty acid
lyoniside	[no description available]	medium	1
thiazolyl blue	[no description available]	medium	1	organic bromide salt	colorimetric reagent; dye
nitrites	[no description available]	medium	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species	human metabolite
thiazoles	[no description available]	medium	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
senegalensin	[no description available]	medium	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; trihydroxyflavanone	antibacterial agent; plant metabolite
lupinifolin	[no description available]	medium	1
indocyanine green	[no description available]	medium	1	1,1-diunsubstituted alkanesulfonate; benzoindole; cyanine dye
sulfobromophthalein	[no description available]	medium	1	2-benzofurans; organobromine compound; organosulfonic acid; phenols	dye
dibromosulphthalein	[no description available]	medium	1
benzofurans	[no description available]	medium	1
isoflavanone	[no description available]	medium	1	isoflavanones
tibolone	[no description available]	low	0	17beta-hydroxy steroid; terminal acetylenic compound	bone density conservation agent; hormone agonist
2,3-dihydroxybenzoic acid	[no description available]	low	0	dihydroxybenzoic acid	human xenobiotic metabolite; plant metabolite
tartronic acid	[no description available]	low	0	dicarboxylic acid; dicarboxylic fatty acid	plant metabolite
protocatechuic acid	[no description available]	low	0	catechols; dihydroxybenzoic acid	antineoplastic agent; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor; human xenobiotic metabolite; plant metabolite
3-phenylpropionic acid	[no description available]	low	0	benzenes; monocarboxylic acid	antifungal agent; human metabolite; plant metabolite
4-hydroxybenzyl alcohol	[no description available]	low	0	benzyl alcohols; phenols	plant metabolite
4-hydroxybenzaldehyde	[no description available]	low	0	hydroxybenzaldehyde	EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor; mouse metabolite; plant metabolite
4-hydroxybenzoic acid	[no description available]	low	0	monohydroxybenzoic acid	algal metabolite; plant metabolite
aminolevulinic acid	[no description available]	low	0	4-oxo monocarboxylic acid; amino acid zwitterion; delta-amino acid	antineoplastic agent; dermatologic drug; Escherichia coli metabolite; human metabolite; mouse metabolite; photosensitizing agent; plant metabolite; prodrug; Saccharomyces cerevisiae metabolite
allantoic acid	[no description available]	low	0	ureas	mouse metabolite; plant metabolite
benzaldehyde	[no description available]	low	0	benzaldehydes	EC 3.1.1.3 (triacylglycerol lipase) inhibitor; EC 3.5.5.1 (nitrilase) inhibitor; flavouring agent; fragrance; odorant receptor agonist; plant metabolite
benzoic acid	[no description available]	low	0	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
betaine aldehyde	[no description available]	low	0	quaternary ammonium ion	Aspergillus metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite
catechol	[no description available]	low	0	catechols	allelochemical; genotoxin; plant metabolite
choline	[no description available]	low	0	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite
coumarin	[no description available]	low	0	coumarins	fluorescent dye; human metabolite; plant metabolite
cuminol	[no description available]	low	0	benzyl alcohols; p-menthane monoterpenoid	fragrance; insect repellent; plant metabolite; volatile oil component; xenobiotic metabolite
cuminaldehyde	[no description available]	low	0	benzaldehydes	insecticide; plant metabolite; volatile oil component
4-vinylguaiacol	[no description available]	low	0	phenols	flavouring agent; pheromone; plant metabolite
4-methylumbelliferyl acetate	[no description available]	low	0	acetate ester; coumarins	plant metabolite
indoleacetamide	[no description available]	low	0	indoles; monocarboxylic acid amide; N-acylammonia	bacterial metabolite; fungal metabolite; plant metabolite
caprylic aldehyde	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	plant metabolite
n(1)-methylnicotinamide	[no description available]	low	0	pyridinium ion	algal metabolite; anti-inflammatory agent; human urinary metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
guaiacol	[no description available]	low	0	guaiacols	disinfectant; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; expectorant; plant metabolite
1-aminocyclopropane-1-carboxylic acid	[no description available]	low	0	amino acid zwitterion; monocarboxylic acid; non-proteinogenic alpha-amino acid	ethylene releasers; plant metabolite
3,4-dihydrocoumarin	[no description available]	low	0	chromanone	plant metabolite
homogentisic acid	[no description available]	low	0	dihydroxyphenylacetic acid; hydroquinones	human metabolite; plant metabolite
indoleacetic acid	[no description available]	low	0	indole-3-acetic acids; monocarboxylic acid	auxin; human metabolite; mouse metabolite; plant hormone; plant metabolite
indol-3-yl pyruvic acid	[no description available]	low	0	2-oxo monocarboxylic acid; indol-3-yl carboxylic acid	plant metabolite; Saccharomyces cerevisiae metabolite
melilotic acid	[no description available]	low	0	monocarboxylic acid; phenols	bacterial xenobiotic metabolite; fungal xenobiotic metabolite; human xenobiotic metabolite; plant metabolite
racemethionine	[no description available]	low	0	alpha-amino acid; amino acid zwitterion; sulfur-containing amino acid	algal metabolite; Daphnia magna metabolite; Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
n-methylphenylethanolamine	[no description available]	low	0	alkaloid; phenylethanolamines	human metabolite; plant metabolite
naphthalene	[no description available]	low	0	naphthalenes; ortho-fused bicyclic arene	apoptosis inhibitor; carcinogenic agent; environmental contaminant; mouse metabolite; plant metabolite; volatile oil component
niacin	[no description available]	low	0	pyridine alkaloid; pyridinemonocarboxylic acid; vitamin B3	antidote; antilipemic drug; EC 3.5.1.19 (nicotinamidase) inhibitor; Escherichia coli metabolite; human urinary metabolite; metabolite; mouse metabolite; plant metabolite; vasodilator agent
1-octanol	[no description available]	low	0	octanol; primary alcohol	antifungal agent; bacterial metabolite; fuel additive; kairomone; plant metabolite
oxalic acid	[no description available]	low	0	alpha,omega-dicarboxylic acid	algal metabolite; human metabolite; plant metabolite
4-aminobenzoic acid	[no description available]	low	0	aminobenzoic acid; aromatic amino-acid zwitterion	allergen; Escherichia coli metabolite; plant metabolite
palmitic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite
phenylacetic acid	[no description available]	low	0	benzenes; monocarboxylic acid; phenylacetic acids	allergen; Aspergillus metabolite; auxin; EC 6.4.1.1 (pyruvate carboxylase) inhibitor; Escherichia coli metabolite; human metabolite; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite; toxin
prephenic acid	[no description available]	low	0	oxo dicarboxylic acid	Escherichia coli metabolite; plant metabolite
pyridoxamine	[no description available]	low	0	aminoalkylpyridine; hydroxymethylpyridine; monohydroxypyridine; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite
pyrogallol	[no description available]	low	0	benzenetriol; phenolic donor	plant metabolite
tryptamine	[no description available]	low	0	aminoalkylindole; aralkylamino compound; indole alkaloid; tryptamines	human metabolite; mouse metabolite; plant metabolite
vanillin	[no description available]	low	0	benzaldehydes; monomethoxybenzene; phenols	anti-inflammatory agent; anticonvulsant; antioxidant; flavouring agent; plant metabolite
aminopropionitrile	[no description available]	low	0	aminopropionitrile	antineoplastic agent; antirheumatic drug; collagen cross-linking inhibitor; plant metabolite
meglutol	[no description available]	low	0	3-hydroxy carboxylic acid; dicarboxylic acid; tertiary alcohol	anticholesteremic drug; antimetabolite; EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor; human metabolite; plant metabolite
methylbufotenin	[no description available]	low	0	aromatic ether; tertiary amino compound; tryptamine alkaloid	hallucinogen; plant metabolite
7,8-dihydroxyflavone	[no description available]	low	0	dihydroxyflavone	antidepressant; antineoplastic agent; antioxidant; plant metabolite; tropomyosin-related kinase B receptor agonist
anabasine	[no description available]	low	0	piperidine alkaloid; pyridine alkaloid	nicotinic acetylcholine receptor agonist; plant metabolite; teratogenic agent
acetovanillone	[no description available]	low	0	acetophenones; aromatic ketone; methyl ketone	antirheumatic drug; EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite
azelaic acid	[no description available]	low	0	alpha,omega-dicarboxylic acid; dicarboxylic fatty acid	antibacterial agent; antineoplastic agent; dermatologic drug; plant metabolite
benzyl benzoate	[no description available]	low	0	benzoate ester; benzyl ester	acaricide; plant metabolite; scabicide
5-methoxypsoralen	[no description available]	low	0	5-methoxyfurocoumarin; organic heterotricyclic compound; psoralens	hepatoprotective agent; plant metabolite
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one	[no description available]	low	0	aromatic ether; benzoxazine; cyclic hydroxamic acid; lactol	allelochemical; plant metabolite
caffeic acid	[no description available]	low	0	catechols; hydroxycinnamic acid	antioxidant; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 2.5.1.18 (glutathione transferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; plant metabolite
caffeine	[no description available]	low	0	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic
beta-glycerophosphoric acid	[no description available]	low	0	glycerol monophosphate	Escherichia coli metabolite; plant metabolite
camphor, (+-)-isomer	[no description available]	low	0	bornane monoterpenoid; cyclic monoterpene ketone	plant metabolite
cetyl alcohol	[no description available]	low	0	hexadecanol; long-chain primary fatty alcohol	algal metabolite; flavouring agent; human metabolite; plant metabolite
chrysanthemic acid	[no description available]	low	0	cyclopropanes; monocarboxylic acid	plant metabolite
colchicine, (+-)-isomer	[no description available]	low	0	acetamides; alkaloid; aromatic ether; carbotricyclic compound	microtubule-destabilising agent; plant metabolite
danthron	[no description available]	low	0	dihydroxyanthraquinone	apoptosis inducer; plant metabolite
decanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; anti-inflammatory agent; antibacterial agent; human metabolite; plant metabolite; volatile oil component
benzophenone	[no description available]	low	0	benzophenones	photosensitizing agent; plant metabolite
ellipticine	[no description available]	low	0	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound; polycyclic heteroarene	antineoplastic agent; plant metabolite
embelin	[no description available]	low	0	dihydroxy-1,4-benzoquinones	antimicrobial agent; antineoplastic agent; hepatitis C protease inhibitor; plant metabolite
guvacine	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; beta-amino acid; pyridine alkaloid; secondary amino compound; tetrahydropyridine	GABA reuptake inhibitor; plant metabolite
beta-thujaplicin	[no description available]	low	0	cyclic ketone; enol; monoterpenoid	antibacterial agent; antifungal agent; antineoplastic agent; antiplasmodial drug; plant metabolite
indole-3-carbinol	[no description available]	low	0	indolyl alcohol	antineoplastic agent; plant metabolite
indolepropionic acid	[no description available]	low	0	indol-3-yl carboxylic acid	auxin; human metabolite; plant metabolite
beta-lapachone	[no description available]	low	0	benzochromenone; orthoquinones	anti-inflammatory agent; antineoplastic agent; plant metabolite
lauric acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; antibacterial agent; plant metabolite
methoxsalen	[no description available]	low	0	aromatic ether; psoralens	antineoplastic agent; cross-linking reagent; dermatologic drug; photosensitizing agent; plant metabolite
masoprocol	[no description available]	low	0	catechols; lignan; tetrol	antioxidant; ferroptosis inhibitor; geroprotector; plant metabolite
phloretin	[no description available]	low	0	dihydrochalcones	antineoplastic agent; plant metabolite
4-aminobenzoic acid	[no description available]	low	0	aminobenzoate; aromatic amino-acid anion	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
protopine	[no description available]	low	0	dibenzazecine alkaloid	plant metabolite
safrole	[no description available]	low	0	benzodioxoles	flavouring agent; insecticide; metabolite; plant metabolite
sebacic acid	[no description available]	low	0	alpha,omega-dicarboxylic acid; dicarboxylic fatty acid	human metabolite; plant metabolite
stearic acid	[no description available]	low	0	long-chain fatty acid; saturated fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; human metabolite; plant metabolite
sulforaphane	[no description available]	low	0	isothiocyanate; sulfoxide	antineoplastic agent; antioxidant; EC 3.5.1.98 (histone deacetylase) inhibitor; plant metabolite
theobromine	[no description available]	low	0	dimethylxanthine	adenosine receptor antagonist; bronchodilator agent; food component; human blood serum metabolite; mouse metabolite; plant metabolite; vasodilator agent
triacetin	[no description available]	low	0	triglyceride	adjuvant; antifungal drug; food additive carrier; food emulsifier; food humectant; fuel additive; plant metabolite; solvent
trigonelline	[no description available]	low	0	alkaloid; iminium betaine	food component; human urinary metabolite; plant metabolite
undecylenic acid	[no description available]	low	0	undecenoic acid	antifungal drug; plant metabolite
reserpine	[no description available]	low	0	alkaloid ester; methyl ester; yohimban alkaloid	adrenergic uptake inhibitor; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; first generation antipsychotic; plant metabolite; xenobiotic
dipropylenetriame	[no description available]	low	0	polyazaalkane	algal metabolite; plant metabolite
vincristine	[no description available]	low	0	acetate ester; formamides; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
levodopa	[no description available]	low	0	amino acid zwitterion; dopa; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	allelochemical; antidyskinesia agent; antiparkinson drug; dopaminergic agent; hapten; human metabolite; mouse metabolite; neurotoxin; plant growth retardant; plant metabolite; prodrug
phenylethyl alcohol	[no description available]	low	0	benzenes; primary alcohol	Aspergillus metabolite; fragrance; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite
phlorhizin	[no description available]	low	0	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	antioxidant; plant metabolite
leucine	[no description available]	low	0	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
phenylalanine	[no description available]	low	0	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
ficusin	[no description available]	low	0	psoralens	plant metabolite
asparagine	[no description available]	low	0	amino acid zwitterion; asparagine; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
n-pentanol	[no description available]	low	0	pentanol; short-chain primary fatty alcohol	human metabolite; plant metabolite
threonine	[no description available]	low	0	amino acid zwitterion; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid; threonine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
alizarin	[no description available]	low	0	dihydroxyanthraquinone	chromophore; dye; plant metabolite
tryptophan	[no description available]	low	0	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
isoleucine	[no description available]	low	0	aspartate family amino acid; isoleucine; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
ethane	[no description available]	low	0	alkane; gas molecular entity	plant metabolite; refrigerant
gibberellic acid	[no description available]	low	0	C19-gibberellin; gibberellin monocarboxylic acid; lactone; organic heteropentacyclic compound	mouse metabolite; plant metabolite
isophorone	[no description available]	low	0	cyclic ketone; enone	plant metabolite; solvent
linalool	[no description available]	low	0	monoterpenoid; tertiary alcohol	antimicrobial agent; fragrance; plant metabolite; volatile oil component
isoprene	[no description available]	low	0	alkadiene; hemiterpene; volatile organic compound	plant metabolite
isobutylamine	[no description available]	low	0	alkylamines	plant metabolite
isobutyric acid	[no description available]	low	0	branched-chain saturated fatty acid; fatty acid 4:0; methyl-branched fatty acid	Daphnia magna metabolite; plant metabolite; volatile oil component
camphene	[no description available]	low	0	carbobicyclic compound; monoterpene	fragrance; plant metabolite
alpha-pinene	[no description available]	low	0	pinene	plant metabolite
purpurin	[no description available]	low	0	trihydroxyanthraquinone	biological pigment; histological dye; plant metabolite
visnagin	[no description available]	low	0	aromatic ether; furanochromone; polyketide	anti-inflammatory agent; antihypertensive agent; EC 1.1.1.37 (malate dehydrogenase) inhibitor; phytotoxin; plant metabolite; vasodilator agent
2,6-dihydroxyanthraquinone	[no description available]	low	0	dihydroxyanthraquinone	antimutagen; plant metabolite
methyl n-methylanthranilate	[no description available]	low	0	benzoate ester; methyl ester; secondary amino compound; substituted aniline	animal metabolite; fungal metabolite; plant metabolite
gramine	[no description available]	low	0	aminoalkylindole; indole alkaloid; tertiary amino compound	antibacterial agent; antiviral agent; plant metabolite; serotonergic antagonist
2-furoic acid	[no description available]	low	0	furoic acid	bacterial xenobiotic metabolite; human xenobiotic metabolite; inhibitor; plant metabolite; Saccharomyces cerevisiae metabolite
piperitone	[no description available]	low	0	cyclic terpene ketone; p-menthane monoterpenoid	plant metabolite; volatile oil component
resacetophenone	[no description available]	low	0	dihydroxyacetophenone; resorcinols	plant metabolite
salicylaldehyde	[no description available]	low	0	hydroxybenzaldehyde	nematicide; plant metabolite
1-methylnaphthalene	[no description available]	low	0	methylnaphthalene	carcinogenic agent; plant metabolite
pseudoephedrine	[no description available]	low	0	phenylethanolamines; secondary alcohol; secondary amino compound	anti-asthmatic drug; bronchodilator agent; central nervous system drug; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
pyrogallol 1,3-dimethyl ether	[no description available]	low	0	dimethoxybenzene; phenols	plant metabolite
veratrole	[no description available]	low	0	dimethoxybenzene	plant metabolite
isatin	[no description available]	low	0	indoledione	EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
phenothiazine	[no description available]	low	0	phenothiazine	ferroptosis inhibitor; plant metabolite; radical scavenger
veratric acid	[no description available]	low	0	benzoic acids	allergen; plant metabolite
synephrine	[no description available]	low	0	ethanolamines; phenethylamine alkaloid; phenols	alpha-adrenergic agonist; plant metabolite
piperonylic acid	[no description available]	low	0	aromatic carboxylic acid; benzodioxoles; monocarboxylic acid	antifungal agent; EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor; plant metabolite; vulnerary
benzothiazole	[no description available]	low	0	benzothiazoles	environmental contaminant; plant metabolite; xenobiotic
2-methylbutanal	[no description available]	low	0	2-methyl-branched fatty aldehyde; methylbutanal	plant metabolite; Saccharomyces cerevisiae metabolite; volatile oil component
methylcyclopentane	[no description available]	low	0	cycloalkane; volatile organic compound	human metabolite; plant metabolite
phosphoribosyl pyrophosphate	[no description available]	low	0	5-O-phosphono-D-ribofuranosyl diphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite
2-methylvaleric acid	[no description available]	low	0	branched-chain saturated fatty acid; methyl-branched fatty acid; monocarboxylic acid; short-chain fatty acid	flavouring agent; fragrance; plant metabolite
ethyl 2-methylpropanoate	[no description available]	low	0	fatty acid ethyl ester	plant metabolite
3-hydroxybenzoic acid	[no description available]	low	0	monohydroxybenzoic acid	bacterial metabolite; plant metabolite
methyl gallate	[no description available]	low	0	gallate ester	anti-inflammatory agent; antioxidant; plant metabolite
carveol	[no description available]	low	0	limonene monoterpenoid	plant metabolite; volatile oil component
methylparaben	[no description available]	low	0	paraben	antifungal agent; antimicrobial food preservative; neuroprotective agent; plant metabolite
alpha phellandrene	[no description available]	low	0	cyclohexadiene; phellandrene	antimicrobial agent; plant metabolite; volatile oil component
gamma-terpinene	[no description available]	low	0	cyclohexadiene; monoterpene	antioxidant; human xenobiotic metabolite; plant metabolite; volatile oil component
alpha-terpinene	[no description available]	low	0	cyclohexadiene; monoterpene	plant metabolite; volatile oil component
4-cymene	[no description available]	low	0	monoterpene; toluenes	human urinary metabolite; plant metabolite; volatile oil component
4-hydroxyacetophenone	[no description available]	low	0	monohydroxyacetophenone	fungal metabolite; mouse metabolite; plant metabolite
4-anisic acid	[no description available]	low	0	methoxybenzoic acid	plant metabolite
styrene	[no description available]	low	0	styrenes; vinylarene; volatile organic compound	mouse metabolite; mutagen; plant metabolite
benzylamine	[no description available]	low	0	aralkylamine; primary amine	allergen; EC 3.5.5.1 (nitrilase) inhibitor; plant metabolite
anisole	[no description available]	low	0	monomethoxybenzene	plant metabolite
phenyl ether	[no description available]	low	0	aromatic ether	plant metabolite
1,3-diphenylurea	[no description available]	low	0	phenylureas	cytokinin; plant metabolite
3-phenylpropanal	[no description available]	low	0	aldehyde; benzenes	flavouring agent; plant metabolite
2-ethylhexanol	[no description available]	low	0	primary alcohol	plant metabolite; volatile oil component
4-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
ethyl butyrate	[no description available]	low	0	butyrate ester	plant metabolite
12-hydroxy stearic acid	[no description available]	low	0	hydroxyoctadecanoic acid; secondary alcohol	bacterial xenobiotic metabolite; plant metabolite
methyl caproate	[no description available]	low	0	fatty acid methyl ester; hexanoate ester	flavouring agent; plant metabolite
propanethiol	[no description available]	low	0	alkanethiol	plant metabolite
allyl alcohol	[no description available]	low	0	primary allylic alcohol; propenol	antibacterial agent; fungicide; herbicide; insecticide; plant metabolite
isoamylamine	[no description available]	low	0	primary aliphatic amine	bacterial metabolite; plant metabolite
2-pentanone	[no description available]	low	0	methyl ketone; pentanone	plant metabolite
methylcyclohexane	[no description available]	low	0	cycloalkane; volatile organic compound	aprotic solvent; human metabolite; plant metabolite
n-pentanoic acid	[no description available]	low	0	short-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
propyl acetate	[no description available]	low	0	acetate ester	fragrance; plant metabolite
allyl cyanide	[no description available]	low	0	aliphatic nitrile; olefinic compound	antifeedant; neurotoxin; plant metabolite
ethyl formate	[no description available]	low	0	ethyl ester; formate ester	fumigant; plant metabolite
pentanal	[no description available]	low	0	saturated fatty aldehyde	plant metabolite
piperidine	[no description available]	low	0	azacycloalkane; piperidines; saturated organic heteromonocyclic parent; secondary amine	base; catalyst; human metabolite; non-polar solvent; plant metabolite; protic solvent; reagent
heptanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
1-hexanol	[no description available]	low	0	hexanol; primary alcohol	alarm pheromone; antibacterial agent; fragrance; plant metabolite
ethyl stearate	[no description available]	low	0	long-chain fatty acid ethyl ester; octadecanoate ester	plant metabolite
heptanol	[no description available]	low	0	heptanol; primary alcohol	flavouring agent; fragrance; gap junctional intercellular communication inhibitor; plant metabolite
nonane	[no description available]	low	0	alkane	plant metabolite; volatile oil component
pelargonic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; antifeedant; Daphnia magna metabolite; plant metabolite
undecan-2-one	[no description available]	low	0	dialkyl ketone; methyl ketone	plant metabolite; rodenticide
octyl acetate	[no description available]	low	0	acetate ester	plant metabolite
decanaldehyde	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	antifungal agent; fragrance; plant metabolite
n-dodecane	[no description available]	low	0	alkane	plant metabolite
undecan-1-ol	[no description available]	low	0	primary alcohol; undecanol	flavouring agent; plant metabolite
undecanal	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	antimycobacterial drug; plant metabolite; volatile oil component
dodecanol	[no description available]	low	0	dodecanol; primary alcohol	bacterial metabolite; cosmetic; insect attractant; insecticide; pheromone; plant metabolite
1-tridecanol	[no description available]	low	0	long-chain primary fatty alcohol; tridecanol	bacterial metabolite; human metabolite; plant metabolite
myristyl alcohol	[no description available]	low	0	long-chain primary fatty alcohol; tetradecanol	pheromone; plant metabolite; volatile oil component
behenic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
stearyl alcohol	[no description available]	low	0	long-chain primary fatty alcohol; octadecanol	algal metabolite; human metabolite; plant metabolite
eicosane	[no description available]	low	0	long-chain alkane	plant metabolite
3-hydroxy-3-methylbutene	[no description available]	low	0	olefinic compound; tertiary alcohol	animal metabolite; fragrance; pheromone; plant metabolite
3,4,5-trimethoxybenzoic acid	[no description available]	low	0	benzoic acids; methoxybenzenes	human urinary metabolite; human xenobiotic metabolite; plant metabolite
2-chlorobenzoic acid	[no description available]	low	0	2-halobenzoic acid; monochlorobenzoic acid	plant hormone; plant metabolite
scoparone	[no description available]	low	0	aromatic ether; coumarins	anti-allergic agent; anti-inflammatory agent; antihypertensive agent; antilipemic drug; immunosuppressive agent; plant metabolite
dimethoxyphenylethylamine	[no description available]	low	0	alkaloid; aromatic ether; phenylethylamine	allergen; plant metabolite
ethyl-p-hydroxybenzoate	[no description available]	low	0	ethyl ester; paraben	antifungal agent; antimicrobial food preservative; phytoestrogen; plant metabolite
piperonal	[no description available]	low	0	arenecarbaldehyde; benzodioxoles	fragrance; insect repellent; plant metabolite
vanillic acid	[no description available]	low	0	methoxybenzoic acid; monohydroxybenzoic acid	plant metabolite
peucedanin	[no description available]	low	0	aromatic ether; furanocoumarin; lactone	plant metabolite
indolebutyric acid	[no description available]	low	0	indol-3-yl carboxylic acid	auxin; plant hormone; plant metabolite
syringaldehyde	[no description available]	low	0	dimethoxybenzene; hydroxybenzaldehyde	hypoglycemic agent; plant metabolite
2-aminothiophenol	[no description available]	low	0	aryl thiol; substituted aniline	plant metabolite
shikimic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; cyclohexenecarboxylic acid; hydroxy monocarboxylic acid	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
estragole	[no description available]	low	0	alkenylbenzene; monomethoxybenzene; phenylpropanoid	carcinogenic agent; flavouring agent; genotoxin; insect attractant; plant metabolite
citronellol	[no description available]	low	0	monoterpenoid	plant metabolite
ethyl acetoacetate	[no description available]	low	0	ethyl ester	antibacterial agent; flavouring agent; plant metabolite
2-hydroxypyridine	[no description available]	low	0	monohydroxypyridine	plant metabolite
hexanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	human metabolite; plant metabolite
n-heptane	[no description available]	low	0	alkane; volatile organic compound	non-polar solvent; plant metabolite
1-nonanol	[no description available]	low	0	nonanol; primary alcohol	antifungal agent; flavouring agent; plant metabolite; volatile oil component
2-vanillin	[no description available]	low	0	benzaldehydes; guaiacols	antimutagen; plant metabolite
citronellyl acetate	[no description available]	low	0	acetate ester; monoterpenoid	plant metabolite
catechin	[no description available]	low	0	catechin	antioxidant; plant metabolite
chrysene	[no description available]	low	0	ortho-fused polycyclic arene	plant metabolite
azulene	[no description available]	low	0	azulenes; mancude carbobicyclic parent; ortho-fused bicyclic arene	plant metabolite; volatile oil component
ephedrine	[no description available]	low	0	phenethylamine alkaloid; phenylethanolamines	bacterial metabolite; environmental contaminant; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
pseudoephedrine hydrochloride	[no description available]	low	0	hydrochloride	plant metabolite
citrulline	[no description available]	low	0	amino acid zwitterion; citrulline	Daphnia magna metabolite; EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; protective agent; Saccharomyces cerevisiae metabolite
4-methylcatechol	[no description available]	low	0	methylcatechol	antioxidant; carcinogenic agent; hapten; human metabolite; plant metabolite
beta-erythroidine	[no description available]	low	0	delta-lactone; indole alkaloid; organic heterotetracyclic compound; tertiary amino compound	muscle relaxant; plant metabolite
pinane	[no description available]	low	0	carbobicyclic compound; monoterpene; terpenoid fundamental parent	plant metabolite
naphthazarin	[no description available]	low	0	hydroxy-1,4-naphthoquinone	acaricide; antibacterial agent; antineoplastic agent; apoptosis inducer; geroprotector; plant metabolite
aloe emodin	[no description available]	low	0	aromatic primary alcohol; dihydroxyanthraquinone	antineoplastic agent; plant metabolite
chrysophanic acid	[no description available]	low	0	dihydroxyanthraquinone	anti-inflammatory agent; antiviral agent; plant metabolite
emetine	[no description available]	low	0	isoquinoline alkaloid; pyridoisoquinoline	antiamoebic agent; anticoronaviral agent; antiinfective agent; antimalarial; antineoplastic agent; antiprotozoal drug; antiviral agent; autophagy inhibitor; emetic; expectorant; plant metabolite; protein synthesis inhibitor
reticulin	[no description available]	low	0	benzylisoquinoline alkaloid; benzyltetrahydroisoquinoline; isoquinolinol	plant metabolite
cytisine	[no description available]	low	0	alkaloid; bridged compound; lactam; organic heterotricyclic compound; secondary amino compound	nicotinic acetylcholine receptor agonist; phytotoxin; plant metabolite
indole-3-carbaldehyde	[no description available]	low	0	heteroarenecarbaldehyde; indole alkaloid; indoles	bacterial metabolite; human xenobiotic metabolite; marine metabolite; plant metabolite
thymoquinone	[no description available]	low	0	1,4-benzoquinones	adjuvant; anti-inflammatory agent; antidepressant; antineoplastic agent; antioxidant; cardioprotective agent; plant metabolite
phenylpropanolamine	[no description available]	low	0	amphetamines; phenethylamine alkaloid	plant metabolite
4-hydroxyphenylethanol	[no description available]	low	0	phenols	anti-arrhythmia drug; antioxidant; cardiovascular drug; fungal metabolite; geroprotector; plant metabolite; protective agent
phloretic acid	[no description available]	low	0	hydroxy monocarboxylic acid	plant metabolite
citronellic acid	[no description available]	low	0	medium-chain fatty acid; monoterpenoid; monounsaturated fatty acid	flavouring agent; plant metabolite
isovaleric acid	[no description available]	low	0	branched-chain saturated fatty acid; methylbutyric acid; short-chain fatty acid	mammalian metabolite; plant metabolite
iberin	[no description available]	low	0	isothiocyanate; sulfoxide	apoptosis inducer; plant metabolite; quorum sensing inhibitor
16-hydroxypalmitic acid	[no description available]	low	0	hydroxypalmitic acid; omega-hydroxy-long-chain fatty acid	plant metabolite
arachidic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
octacosanoic acid	[no description available]	low	0	straight-chain saturated fatty acid; ultra-long-chain fatty acid	plant metabolite
ascaridole	[no description available]	low	0	organic heterobicyclic compound; organic peroxide; p-menthane monoterpenoid	antileishmanial agent; antinematodal drug; plant metabolite
abietic acid	[no description available]	low	0	abietane diterpenoid; monocarboxylic acid	plant metabolite
hematoxylin	[no description available]	low	0	organic heterotetracyclic compound; oxacycle; polyphenol; tertiary alcohol	histological dye; plant metabolite
podophyllotoxin	[no description available]	low	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antimitotic; antineoplastic agent; keratolytic drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
pyridoxamine dihydrochloride	[no description available]	low	0	hydrochloride; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite
tryptophol	[no description available]	low	0	indolyl alcohol	auxin; plant metabolite; Saccharomyces cerevisiae metabolite
hemimellitene	[no description available]	low	0	trimethylbenzene	neurotoxin; plant metabolite
2-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
syringic acid	[no description available]	low	0	benzoic acids; dimethoxybenzene; phenols	plant metabolite
6-methoxybenzoxazolinone	[no description available]	low	0	aromatic ether; benzoxazole	antibacterial agent; anticonvulsant; antifungal agent; muscle relaxant; plant metabolite
1,1-dimethoxyethane	[no description available]	low	0	acetal; diether	flavouring agent; plant metabolite
2-methylfuran	[no description available]	low	0	furans; volatile organic compound	flavouring agent; fuel; hepatotoxic agent; human urinary metabolite; plant metabolite
perillyl alcohol	[no description available]	low	0	limonene monoterpenoid	plant metabolite; volatile oil component
cumic acid	[no description available]	low	0	cumic acid	plant metabolite
tricaprylin	[no description available]	low	0	octanoate ester; triglyceride	anticonvulsant; plant metabolite
senecioic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; methyl-branched fatty acid; monounsaturated fatty acid; short-chain fatty acid	plant metabolite
3-hexen-1-ol	[no description available]	low	0	alkenyl alcohol; homoallylic alcohol; primary alcohol; volatile organic compound	plant metabolite
n-hexadecane	[no description available]	low	0	long-chain alkane	non-polar solvent; plant metabolite; volatile oil component
beta-phellandrene	[no description available]	low	0	phellandrene	plant metabolite
tristearin	[no description available]	low	0	triacylglycerol 54:0	Caenorhabditis elegans metabolite; plant metabolite
lignoceric acid	[no description available]	low	0	straight-chain saturated fatty acid; very long-chain fatty acid	Daphnia tenebrosa metabolite; human metabolite; plant metabolite; volatile oil component
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol	[no description available]	low	0	terpineol; tertiary alcohol	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiparasitic agent; apoptosis inducer; plant metabolite; volatile oil component
6-methylsalicylic acid	[no description available]	low	0	monohydroxybenzoic acid	Penicillium metabolite; plant metabolite
1-phenyl-1,2-propanedione	[no description available]	low	0	alpha-diketone; aromatic ketone	plant metabolite
2-methylcyclohexanone	[no description available]	low	0	cyclohexanones	flavouring agent; plant metabolite
terpinolene	[no description available]	low	0	p-menthadiene	insect repellent; plant metabolite; sedative; volatile oil component
isovalerylaldehyde	[no description available]	low	0	methylbutanal	flavouring agent; plant metabolite; Saccharomyces cerevisiae metabolite; volatile oil component
levulinic acid	[no description available]	low	0	oxopentanoic acid; straight-chain saturated fatty acid	plant metabolite
2-tridecanone	[no description available]	low	0	methyl ketone	flavouring agent; plant metabolite
octadecane	[no description available]	low	0	long-chain alkane	bacterial metabolite; plant metabolite
dimethylselenide	[no description available]	low	0	organoselenium compound	bacterial xenobiotic metabolite; plant metabolite
chorismic acid	[no description available]	low	0	5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
2-methyl-5-(1-methylethenyl)cyclohexanol	[no description available]	low	0	p-menthane monoterpenoid; secondary alcohol	acaricide; plant metabolite; volatile oil component
4-carboxybenzaladehyde	[no description available]	low	0	benzaldehydes; benzoic acids; monocarboxylic acid	plant metabolite
3-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
isovanillin	[no description available]	low	0	benzaldehydes; monomethoxybenzene; phenols	animal metabolite; antidiarrhoeal drug; antifungal agent; EC 1.2.3.1 (aldehyde oxidase) inhibitor; HIV protease inhibitor; plant metabolite
2,5-dimethylfuran	[no description available]	low	0	furans	antifungal agent; bacterial metabolite; fuel; fumigant; human urinary metabolite; Maillard reaction product; plant metabolite
2-hexanol	[no description available]	low	0	hexanol; secondary alcohol	human metabolite; plant metabolite; semiochemical
ethyl palmitate	[no description available]	low	0	hexadecanoate ester; long-chain fatty acid ethyl ester	plant metabolite
2-nonanol	[no description available]	low	0	nonanol; secondary alcohol	bacterial metabolite; flavouring agent; pheromone; plant metabolite; rat metabolite; volatile oil component
n-propyl disulfide	[no description available]	low	0	organic disulfide	plant metabolite
tridecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
n-tetradecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
pentadecane	[no description available]	low	0	long-chain alkane	animal metabolite; plant metabolite; volatile oil component
heptadecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
nonadecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
n-heneicosane	[no description available]	low	0	long-chain alkane	pheromone; plant metabolite; volatile oil component
docosane	[no description available]	low	0	long-chain alkane	plant metabolite
octacosane	[no description available]	low	0	long-chain alkane	plant metabolite
nonacosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
bulbocapnine	[no description available]	low	0	aporphine alkaloid; aromatic ether; oxacycle; phenols	EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor; EC 1.4.3.22 (diamine oxidase) inhibitor; plant metabolite
1,2,3-trimethoxybenzene	[no description available]	low	0	methoxybenzenes	plant metabolite
2-pyrrolecarboxylic acid	[no description available]	low	0	pyrrolecarboxylic acid	plant metabolite
tridecanoic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
n-tricosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
2-propylphenol	[no description available]	low	0	phenols	flavouring agent; plant metabolite
isovanillic acid	[no description available]	low	0	methoxybenzoic acid; monohydroxybenzoic acid	antibacterial agent; plant metabolite
tetracosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
docosanol	[no description available]	low	0	docosanol; long-chain primary fatty alcohol	antiviral drug; plant metabolite
2-methylpyrrolidine	[no description available]	low	0	pyrrolidines	plant metabolite
2-nonanone	[no description available]	low	0	methyl ketone	plant metabolite
ethyl gallate	[no description available]	low	0	gallate ester	plant metabolite
3-methylfuran	[no description available]	low	0	furans; volatile organic compound	Aspergillus metabolite; environmental contaminant; fungal metabolite; Penicillium metabolite; plant metabolite
pentadecanoic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; food component; human blood serum metabolite; plant metabolite
dihydroferulic acid	[no description available]	low	0	guaiacols; monocarboxylic acid; phenylpropanoid	antioxidant; human xenobiotic metabolite; mouse metabolite; plant metabolite
fenchone, (+-)-isomer	[no description available]	low	0	carbobicyclic compound; cyclic terpene ketone; fenchane monoterpenoid	plant metabolite
beta-pinene	[no description available]	low	0	pinene	plant metabolite
d-alpha tocopherol	[no description available]	low	0	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite
selenomethionine	[no description available]	low	0	selenoamino acid; selenomethionines	plant metabolite
1-pentene-3-one	[no description available]	low	0	enone	flavouring agent; genotoxin; human metabolite; plant metabolite
dodecyldimethylamine oxide	[no description available]	low	0	tertiary amine oxide	detergent; plant metabolite
2-undecanol	[no description available]	low	0	secondary alcohol; undecanol	animal metabolite; flavouring agent; pheromone; plant metabolite; volatile oil component
digoxigenin	[no description available]	low	0	12beta-hydroxy steroid; 14beta-hydroxy steroid; 3beta-hydroxy steroid; 3beta-sterol	hapten; plant metabolite
heliamine	[no description available]	low	0	aromatic ether; diether; isoquinoline alkaloid; isoquinolines	plant metabolite
6h-dibenzo-(b,d)-pyran-6-one	[no description available]	low	0	benzochromenone	plant metabolite
diallyl disulfide	[no description available]	low	0	organic disulfide	antifungal agent; antineoplastic agent; plant metabolite
glaucine	[no description available]	low	0	aporphine alkaloid; organic heterotetracyclic compound; polyether; tertiary amino compound	antibacterial agent; antineoplastic agent; antitussive; muscle relaxant; NF-kappaB inhibitor; plant metabolite; platelet aggregation inhibitor; rat metabolite
dihydroconiferyl alcohol	[no description available]	low	0	eugenol; primary alcohol	plant metabolite
propyl benzoate	[no description available]	low	0	benzoate ester	antimicrobial food preservative; flavouring agent; plant metabolite
2-methoxy-1,4-naphthoquinone	[no description available]	low	0	1,4-naphthoquinones; enol ether	antimicrobial agent; metabolite; plant metabolite
tricosanoic acid	[no description available]	low	0	straight-chain saturated fatty acid; very long-chain fatty acid	Daphnia magna metabolite; human metabolite; plant metabolite
alpha-terpineol	[no description available]	low	0	terpineol	plant metabolite
acetosyringone	[no description available]	low	0	acetophenones; dimethoxybenzene; phenols	anti-asthmatic drug; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite
pentadecanal	[no description available]	low	0	2,3-saturated fatty aldehyde; long-chain fatty aldehyde	antimicrobial agent; plant metabolite; volatile oil component
2-ethylfuran	[no description available]	low	0	furans; volatile organic compound	bacterial metabolite; fragrance; Maillard reaction product; plant metabolite
sabinene	[no description available]	low	0	thujene	plant metabolite
palmatine	[no description available]	low	0	berberine alkaloid; organic heterotetracyclic compound	plant metabolite
n-butylbenzenesulfonamide	[no description available]	low	0	sulfonamide	neurotoxin; plant metabolite
furaneol	[no description available]	low	0	cyclic ketone; enol; furans	flavouring agent; fragrance; plant metabolite
methyl vanillate	[no description available]	low	0	aromatic ether; benzoate ester; phenols	antioxidant; plant metabolite
2-octanol	[no description available]	low	0	octanol; secondary alcohol	plant metabolite; volatile oil component
5-methoxyindole-2-carboxylic acid	[no description available]	low	0	aromatic ether; indolecarboxylic acid	EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor; hypoglycemic agent; plant metabolite
canadine, (s)-isomer	[no description available]	low	0	an (S)-7,8,13,14-tetrahydroprotoberberine; canadine	plant metabolite
14-methylhexadecanoic acid	[no description available]	low	0	branched-chain saturated fatty acid; long-chain fatty acid; methyl-branched fatty acid	mammalian metabolite; plant metabolite
helenalin	[no description available]	low	0	cyclic ketone; gamma-lactone; organic heterotricyclic compound; secondary alcohol; sesquiterpene lactone	anti-inflammatory agent; antineoplastic agent; metabolite; plant metabolite
dimethyldiselenide	[no description available]	low	0	organoselenium compound	bacterial metabolite; human xenobiotic metabolite; mammalian metabolite; plant metabolite
camptothecin	[no description available]	low	0	delta-lactone; pyranoindolizinoquinoline; quinoline alkaloid; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; genotoxin; plant metabolite
isopentenyladenosine	[no description available]	low	0	N-ribosyl-N(6)-isopentenyladenine; nucleoside analogue	antineoplastic agent; plant growth regulator; plant metabolite
s-methylcysteine	[no description available]	low	0	S-alkyl-L-cysteine zwitterion; S-alkyl-L-cysteine	human urinary metabolite; plant metabolite
dihydrocarvone	[no description available]	low	0	dihydrocarvones	plant metabolite
marmesin, (r)-isomer	[no description available]	low	0	marmesin	plant metabolite; rat metabolite; xenobiotic metabolite
4-hydroxybenzylcyanide	[no description available]	low	0	hydroxynitrile	plant metabolite
2,3,5-trimethylpyrazine	[no description available]	low	0	pyrazines	animal metabolite; bacterial metabolite; flavouring agent; pheromone; plant metabolite
tetradecanoylphorbol acetate	[no description available]	low	0	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator
2,4-dihydroxy-1,4-benzoxazin-3-one	[no description available]	low	0	benzoxazine; cyclic hydroxamic acid; lactol	allelochemical; herbicide; phytotoxin; plant metabolite
precocene i	[no description available]	low	0	aromatic ether; chromenes	plant metabolite; precocenes
1-deoxynojirimycin	[no description available]	low	0	2-(hydroxymethyl)piperidine-3,4,5-triol; piperidine alkaloid	anti-HIV agent; anti-obesity agent; bacterial metabolite; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; plant metabolite
neohesperidin dihydrochalcone	[no description available]	low	0	dihydrochalcones; disaccharide derivative; neohesperidoside	environmental contaminant; plant metabolite; sweetening agent; xenobiotic
zingerone	[no description available]	low	0	methyl ketone; monomethoxybenzene; phenols	anti-inflammatory agent; antiemetic; antioxidant; flavouring agent; fragrance; plant metabolite; radiation protective agent
4-anisaldehyde	[no description available]	low	0	benzaldehydes	bacterial metabolite; human urinary metabolite; insect repellent; plant metabolite
myrcene	[no description available]	low	0	monoterpene	anabolic agent; anti-inflammatory agent; flavouring agent; fragrance; plant metabolite; volatile oil component
diacetone alcohol	[no description available]	low	0	beta-hydroxy ketone	plant metabolite
methyl tetradecanoate	[no description available]	low	0	fatty acid methyl ester	flavouring agent; fragrance; plant metabolite
nonanal	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	human metabolite; plant metabolite
tetradecanal	[no description available]	low	0	2,3-saturated fatty aldehyde; long-chain fatty aldehyde	bacterial metabolite; plant metabolite
silybin	[no description available]	low	0	aromatic ether; benzodioxine; flavonolignan; polyphenol; secondary alpha-hydroxy ketone	antineoplastic agent; antioxidant; hepatoprotective agent; plant metabolite
oxypeucadanin, (s)-(-)-isomer	[no description available]	low	0	epoxide; furanocoumarin; lactone	plant metabolite
amygdalin	[no description available]	low	0	cyanogenic glycoside; disaccharide derivative; gentiobioside	plant metabolite
colforsin	[no description available]	low	0	acetate ester; cyclic ketone; labdane diterpenoid; organic heterotricyclic compound; tertiary alpha-hydroxy ketone; triol	adenylate cyclase agonist; anti-HIV agent; antihypertensive agent; plant metabolite; platelet aggregation inhibitor; protein kinase A agonist
swainsonine	[no description available]	low	0	indolizidine alkaloid	antineoplastic agent; EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor; immunological adjuvant; plant metabolite
octyl gallate	[no description available]	low	0	gallate ester	food antioxidant; hypoglycemic agent; plant metabolite
vanillyl alcohol	[no description available]	low	0	benzyl alcohols; guaiacols	plant metabolite
benzylaminopurine	[no description available]	low	0	6-aminopurines	cytokinin; plant metabolite
allyl methyl disulfide	[no description available]	low	0	organic disulfide	plant metabolite; volatile oil component
octyl glucoside	[no description available]	low	0	beta-D-glucoside	plant metabolite
dihydrochalcone	[no description available]	low	0	dihydrochalcones	plant metabolite
betulinic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid	anti-HIV agent; anti-inflammatory agent; antimalarial; antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; plant metabolite
calanolide a	[no description available]	low	0	cyclic ether; delta-lactone; organic heterotetracyclic compound; secondary alcohol	HIV-1 reverse transcriptase inhibitor; plant metabolite
baicalin	[no description available]	low	0	dihydroxyflavone; glucosiduronic acid; glycosyloxyflavone; monosaccharide derivative	antiatherosclerotic agent; antibacterial agent; anticoronaviral agent; antineoplastic agent; antioxidant; cardioprotective agent; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; ferroptosis inhibitor; neuroprotective agent; non-steroidal anti-inflammatory drug; plant metabolite; prodrug
aica ribonucleotide	[no description available]	low	0	1-(phosphoribosyl)imidazolecarboxamide; aminoimidazole	cardiovascular drug; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
salvin	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; catechols; monocarboxylic acid	angiogenesis modulating agent; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; food preservative; HIV protease inhibitor; plant metabolite
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose	[no description available]	low	0	gallate ester; galloyl beta-D-glucose	anti-inflammatory agent; antineoplastic agent; geroprotector; hepatoprotective agent; plant metabolite; radiation protective agent; radical scavenger
obtusifoliol	[no description available]	low	0	14alpha-methyl steroid; 3beta-sterol	mouse metabolite; plant metabolite
baccatin iii	[no description available]	low	0	acetate ester; benzoate ester; tetracyclic diterpenoid	plant metabolite
secoisolariciresinol	[no description available]	low	0	secoisolariciresinol	antidepressant; phytoestrogen; plant metabolite
solanidine	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; solanid-5-en-3-ol; steroid alkaloid fundamental parent	plant metabolite; toxin
valerophenone	[no description available]	low	0	aromatic ketone	plant metabolite; volatile oil component
2,4,6-trihydroxyacetophenone	[no description available]	low	0	aromatic ketone; benzenetriol; methyl ketone	MALDI matrix material; plant metabolite
tangeretin	[no description available]	low	0	pentamethoxyflavone	antineoplastic agent; plant metabolite
djenkolic acid	[no description available]	low	0	dithioacetal; L-cysteine derivative; non-proteinogenic L-alpha-amino acid	plant metabolite; toxin
1-hexacosanol	[no description available]	low	0	hexacosanol; very long-chain primary fatty alcohol	insecticide; plant metabolite
actinidine	[no description available]	low	0	cyclopentapyridine; pyridine alkaloid	pheromone; plant metabolite
7-methylxanthine	[no description available]	low	0	oxopurine; purine alkaloid	human xenobiotic metabolite; mouse metabolite; plant metabolite
1-octacosanol	[no description available]	low	0	fatty alcohol 28:0; ultra-long-chain primary fatty alcohol	plant metabolite
suberosin	[no description available]	low	0	aromatic ether; coumarins	anticoagulant; plant metabolite
artemisinin	[no description available]	low	0	organic peroxide; sesquiterpene lactone	antimalarial; plant metabolite
isoscopoletin	[no description available]	low	0	aromatic ether; hydroxycoumarin	plant metabolite
methyl syringate	[no description available]	low	0	benzoate ester; dimethoxybenzene; phenols	plant metabolite
tetrahydroalstonine	[no description available]	low	0	methyl ester; organic heteropentacyclic compound; yohimban alkaloid	plant metabolite
nobiletin	[no description available]	low	0	methoxyflavone	antineoplastic agent; plant metabolite
lycorine	[no description available]	low	0	indolizidine alkaloid	anticoronaviral agent; antimalarial; plant metabolite; protein synthesis inhibitor
picropodophyllin	[no description available]	low	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antineoplastic agent; insulin-like growth factor receptor 1 antagonist; plant metabolite; tyrosine kinase inhibitor
alantolactone	[no description available]	low	0	naphthofuran; olefinic compound; sesquiterpene lactone	antineoplastic agent; apoptosis inducer; plant metabolite
vexibinol	[no description available]	low	0	(2S)-flavan-4-one; 4'-hydroxyflavanones; tetrahydroxyflavanone	antimalarial; antimicrobial agent; antioxidant; plant metabolite
kaurenoic acid	[no description available]	low	0	ent-kaurane diterpenoid	anti-HIV-1 agent; antineoplastic agent; plant metabolite
pinostrobin	[no description available]	low	0	monohydroxyflavanone; monomethoxyflavanone	antidote; plant metabolite
xanthomicrol	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	antineoplastic agent; plant metabolite
voacamine	[no description available]	low	0	alkaloid ester; methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; plant metabolite
isoalantolactone	[no description available]	low	0	eudesmane sesquiterpenoid; sesquiterpene lactone	antifungal agent; apoptosis inducer; plant metabolite
pulsatilla saponin a	[no description available]	low	0	disaccharide derivative; hydroxy monocarboxylic acid; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
hederagenin	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid; sapogenin	plant metabolite
magnoflorine	[no description available]	low	0	aporphine alkaloid; quaternary ammonium ion	plant metabolite
brazilin	[no description available]	low	0	catechols; organic heterotetracyclic compound; tertiary alcohol	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; apoptosis inducer; biological pigment; hepatoprotective agent; histological dye; NF-kappaB inhibitor; plant metabolite
strychnine n-oxide	[no description available]	low	0	monoterpenoid indole alkaloid; organic heteroheptacyclic compound; tertiary amine oxide	plant metabolite
pinoresinol	[no description available]	low	0	pinoresinol	hypoglycemic agent; phytoestrogen; plant metabolite
dauricine	[no description available]	low	0	aromatic ether; bisbenzylisoquinoline alkaloid; isoquinolines; phenols; tertiary amino compound	plant metabolite
madecassic acid	[no description available]	low	0	monocarboxylic acid; pentacyclic triterpenoid; tetrol	antioxidant; plant metabolite
uvaretin	[no description available]	low	0	aromatic ether; dihydrochalcones; polyketide; resorcinol	antineoplastic agent; plant metabolite
fangchinoline	[no description available]	low	0	aromatic ether; bisbenzylisoquinoline alkaloid; macrocycle	anti-HIV-1 agent; anti-inflammatory agent; antineoplastic agent; antioxidant; neuroprotective agent; plant metabolite
maslinic acid	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; plant metabolite
indole-5-carboxylic acid	[no description available]	low	0	indolecarboxylic acid	plant metabolite
1,3,7,9-tetramethyluric acid	[no description available]	low	0	oxopurine; purine alkaloid	analgesic; anti-inflammatory agent; human xenobiotic metabolite; plant metabolite
phenylalanylleucine	[no description available]	low	0	dipeptide zwitterion; dipeptide	plant metabolite
ethyl protocatechuate	[no description available]	low	0	catechols; ethyl ester	antibacterial agent; antioxidant; apoptosis inducer; EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor; plant metabolite
3,5-dimethoxytoluene	[no description available]	low	0	methoxybenzenes; toluenes	fragrance; plant metabolite
methylthioethanol	[no description available]	low	0	aliphatic sulfide; primary alcohol	plant metabolite; xenobiotic metabolite
cryptolepine	[no description available]	low	0	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound	anti-inflammatory agent; antimalarial; antineoplastic agent; cysteine protease inhibitor; plant metabolite
alpha-bergamotene	[no description available]	low	0	bridged compound; polycyclic olefin; sesquiterpene	plant metabolite; volatile oil component
4-methyl-4-sulfanylpentan-2-one	[no description available]	low	0	alkanethiol; methyl ketone	plant metabolite; Saccharomyces cerevisiae metabolite
nicotine	[no description available]	low	0	3-(1-methylpyrrolidin-2-yl)pyridine	anxiolytic drug; biomarker; immunomodulator; mitogen; neurotoxin; nicotinic acetylcholine receptor agonist; peripheral nervous system drug; phytogenic insecticide; plant metabolite; psychotropic drug; teratogenic agent; xenobiotic
loganic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; cyclopentapyran; glucoside	plant metabolite
friedelin	[no description available]	low	0	cyclic terpene ketone; pentacyclic triterpenoid	anti-inflammatory drug; antipyretic; non-narcotic analgesic; plant metabolite
cholest-4-en-3-one	[no description available]	low	0	3-oxo-Delta(4) steroid; cholestanoid	human metabolite; plant metabolite
delta-tocopherol	[no description available]	low	0	tocopherol; vitamin E	food antioxidant; plant metabolite
cycloartenol	[no description available]	low	0	3beta-sterol; pentacyclic triterpenoid; phytosterols	plant metabolite
beta-peltatin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; organic heterotetracyclic compound; phenols	antineoplastic agent; plant metabolite
elemol	[no description available]	low	0	olefinic compound; sesquiterpenoid; tertiary alcohol	fragrance; plant metabolite
spathulenol	[no description available]	low	0	carbotricyclic compound; olefinic compound; sesquiterpenoid; tertiary alcohol	anaesthetic; plant metabolite; vasodilator agent; volatile oil component
mor-14	[no description available]	low	0	hydroxypiperidine; piperidine alkaloid; tertiary amino compound	anti-HIV agent; cardioprotective agent; EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite
gamma-tocopherol	[no description available]	low	0	tocopherol; vitamin E	algal metabolite; food antioxidant; plant metabolite
orotidine	[no description available]	low	0	nucleoside; pyrimidinemonocarboxylic acid; uridines	bacterial metabolite; fungal metabolite; plant metabolite
sugiol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; cyclic terpene ketone; meroterpenoid; phenols	antineoplastic agent; antioxidant; antiviral agent; plant metabolite; radical scavenger
erythrose	[no description available]	low	0	erythrose	plant metabolite
24-methylene cycloartanol	[no description available]	low	0	3beta-hydroxy steroid; pentacyclic triterpenoid	plant metabolite
panose	[no description available]	low	0	trisaccharide	plant metabolite
bursehernin	[no description available]	low	0	aromatic ether; benzodioxoles; butan-4-olide; lignan	plant metabolite
sesaminol	[no description available]	low	0	benzodioxoles; furofuran; organic hydroxy compound	antioxidant; plant metabolite
4',5,6,7-tetramethoxyflavone	[no description available]	low	0	tetramethoxyflavone	antimutagen; plant metabolite
gardenin b	[no description available]	low	0	monohydroxyflavone; tetramethoxyflavone	plant metabolite
quercetin 5,7,3',4'-tetramethyl ether	[no description available]	low	0	flavonols; tetramethoxyflavone	plant metabolite
1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid	[no description available]	low	0	alpha-amino acid; aromatic amino acid; beta-carboline alkaloid	human urinary metabolite; human xenobiotic metabolite; plant metabolite; rat metabolite
sarsasapogenin, (3beta,5alpha,25r)-isomer	[no description available]	low	0	sapogenin	gout suppressant; plant metabolite
syringaresinol	[no description available]	low	0	aromatic ether; furofuran; lignan; polyether; polyphenol	plant metabolite
cyclolaudenol	[no description available]	low	0	3beta-hydroxy steroid; pentacyclic triterpenoid	plant metabolite
galgravin	[no description available]	low	0	aryltetrahydrofuran; dimethoxybenzene; lignan; ring assembly	bone density conservation agent; neuroprotective agent; plant metabolite; platelet aggregation inhibitor
erythrodiol	[no description available]	low	0	diol; pentacyclic triterpenoid; primary alcohol; secondary alcohol	plant metabolite
6,6-dimethyl-2-methylenebicyclo(3.1.1)heptan-3-ol	[no description available]	low	0	carbobicyclic compound; pinane monoterpenoid; secondary alcohol	GABA modulator; mouse metabolite; plant metabolite; volatile oil component
selenomethionine	[no description available]	low	0	amino acid zwitterion; selenomethionine	plant metabolite
deguelin	[no description available]	low	0	aromatic ether; diether; organic heteropentacyclic compound; rotenones	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor; plant metabolite
1,9-dideoxyforskolin	[no description available]	low	0	acetate ester; labdane diterpenoid; organic heterotricyclic compound	plant metabolite
triptolide	[no description available]	low	0	diterpenoid; epoxide; gamma-lactam; organic heteroheptacyclic compound	antispermatogenic agent; plant metabolite
indospicine	[no description available]	low	0	carboxamidine; non-proteinogenic L-alpha-amino acid	hepatotoxic agent; plant metabolite
cafestol	[no description available]	low	0	diterpenoid; furans; organic heteropentacyclic compound; primary alcohol; tertiary alcohol	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; plant metabolite
nimbin	[no description available]	low	0	acetate ester; cyclic terpene ketone; enone; furans; limonoid; methyl ester; tetracyclic triterpenoid	pesticide; plant metabolite
neoeriocitrin	[no description available]	low	0	4'-hydroxyflavanones; disaccharide derivative; flavanone glycoside; neohesperidoside; trihydroxyflavanone	plant metabolite
kahweol	[no description available]	low	0	diterpenoid; furans; organic heteropentacyclic compound; primary alcohol; tertiary alcohol	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; plant metabolite
valerates	[no description available]	low	0	short-chain fatty acid anion; straight-chain saturated fatty acid anion	plant metabolite
s-sulphocysteine	[no description available]	low	0	organic thiosulfate; S-substituted L-cysteine	human metabolite; plant metabolite
megestrol acetate	[no description available]	low	0	bridged compound; organic heterotetracyclic compound; secondary alcohol; sesquiterpene lactone; spiro compound; tertiary alcohol; tetrol	GABA antagonist; neurotoxin; phytogenic insecticide; plant metabolite
stachydrine	[no description available]	low	0	alkaloid; amino-acid betaine; N-methyl-L-alpha-amino acid	food component; human blood serum metabolite; plant metabolite
echinuline	[no description available]	low	0	2,5-diketopiperazines; indole alkaloid; indoles; olefinic compound	Aspergillus metabolite; marine metabolite; plant metabolite
cubebin	[no description available]	low	0	benzodioxoles; cyclic acetal; lactol; lignan; secondary alcohol	analgesic; anti-inflammatory agent; antimicrobial agent; histamine antagonist; plant metabolite; trypanocidal drug
1'-acetoxychavicol acetate	[no description available]	low	0	acetate ester; phenylpropanoid	antineoplastic agent; NF-kappaB inhibitor; plant metabolite
hydrangenol	[no description available]	low	0	dihydroisocoumarins; phenols	anti-allergic agent; plant metabolite
matairesinol	[no description available]	low	0	gamma-lactone; lignan; polyphenol	angiogenesis inhibitor; anti-asthmatic agent; phytoestrogen; plant metabolite
ginsenoside rh2	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; bone density conservation agent; cardioprotective agent; hepatoprotective agent; plant metabolite
mannopine	[no description available]	low	0	amino acid opine; dicarboxylic acid monoamide; hexitol derivative; L-glutamine derivative; non-proteinogenic L-alpha-amino acid; secondary amino compound	plant metabolite
ribulose-1,5 diphosphate	[no description available]	low	0	ribulose phosphate	Escherichia coli metabolite; plant metabolite
glabranin	[no description available]	low	0	(2S)-flavan-4-one; dihydroxyflavanone	plant metabolite
rubiadin	[no description available]	low	0	dihydroxyanthraquinone	antibacterial agent; antioxidant; hepatoprotective agent; plant metabolite
soranjidiol	[no description available]	low	0	dihydroxyanthraquinone	antibacterial agent; plant metabolite
skullcapflavone ii	[no description available]	low	0	dihydroxyflavone; tetramethoxyflavone	anti-asthmatic drug; plant metabolite
rubimaillin	[no description available]	low	0	benzochromene; methyl ester; phenols	acyl-CoA:cholesterol acyltransferase 2 inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; neuroprotective agent; NF-kappaB inhibitor; plant metabolite
tiglic acid	[no description available]	low	0	2-methylbut-2-enoic acid	plant metabolite
psorospermin	[no description available]	low	0	epoxide; organic heterotetracyclic compound; xanthones	antineoplastic agent; plant metabolite
delphinidin	[no description available]	low	0	5-hydroxyanthocyanidin	antineoplastic agent; biological pigment; plant metabolite
n-methylserotonin	[no description available]	low	0	phenols; tryptamines	human metabolite; plant metabolite
lyxonic acid	[no description available]	low	0	lyxonic acid	plant metabolite
kolaviron	[no description available]	low	0	4'-methoxyflavanones; biflavonoid; dihydroflavonols; ring assembly; secondary alpha-hydroxy ketone	hepatoprotective agent; plant metabolite
spinosin	[no description available]	low	0	dihydroxyflavone; flavone C-glycoside; monomethoxyflavone	anxiolytic drug; plant metabolite
schizandrin b	[no description available]	low	0	aromatic ether; cyclic acetal; organic heterotetracyclic compound; oxacycle; tannin	anti-asthmatic agent; anti-inflammatory agent; antilipemic drug; antioxidant; apoptosis inhibitor; hepatoprotective agent; nephroprotective agent; neuroprotective agent; plant metabolite
acrovestone	[no description available]	low	0	acetophenones; aromatic ether; olefinic compound; polyphenol	antioxidant; EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
matteucinol	[no description available]	low	0	4'-methoxyflavanones; dihydroxyflavanone; monomethoxyflavanone	plant metabolite; radical scavenger
guvacoline	[no description available]	low	0	alpha,beta-unsaturated carboxylic ester; beta-amino acid ester; enoate ester; methyl ester; pyridine alkaloid; secondary amino compound; tetrahydropyridine	muscarinic agonist; plant metabolite
corytuberine	[no description available]	low	0	aporphine alkaloid; aromatic ether; organic heterotetracyclic compound; polyphenol; tertiary amino compound	plant metabolite
actinodaphine	[no description available]	low	0	aporphine alkaloid; aromatic ether; organic heteropentacyclic compound; phenols; secondary amino compound	antibacterial agent; antifungal agent; antineoplastic agent; apoptosis inducer; plant metabolite; platelet aggregation inhibitor; topoisomerase inhibitor
ar-turmerone	[no description available]	low	0	enone; sesquiterpenoid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; plant metabolite
isolariciresinol	[no description available]	low	0	guaiacols; lignan; polyphenol; primary alcohol	plant metabolite
4'-demethyldesoxypodophyllotoxin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes; phenols	antineoplastic agent; antioxidant; immunosuppressive agent; plant metabolite
t-cadinol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	plant metabolite; volatile oil component
1-hydroxy-2-methylanthraquinone	[no description available]	low	0	monohydroxyanthraquinone	plant metabolite
nevadensin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
salvigenin	[no description available]	low	0	monohydroxyflavone; trimethoxyflavone	antilipemic drug; antineoplastic agent; apoptosis inhibitor; autophagy inducer; hypoglycemic agent; immunomodulator; neuroprotective agent; plant metabolite
secologanin	[no description available]	low	0	aldehyde; beta-D-glucoside; enoate ester; methyl ester; pyrans; secoiridoid glycoside	plant metabolite
columbianetin acetate	[no description available]	low	0	acetate ester; furanocoumarin	plant metabolite
maprounic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid	HIV-1 reverse transcriptase inhibitor; plant metabolite
acetyl aleuritolic acid	[no description available]	low	0	acetate ester; monocarboxylic acid; pentacyclic triterpenoid	antineoplastic agent; plant metabolite
myricanone	[no description available]	low	0	aromatic ether; cyclic ketone; diarylheptanoid; methoxybenzenes; phenols	antineoplastic agent; plant metabolite
glycyrrhetyl 3-monoglucuronide	[no description available]	low	0	beta-D-glucosiduronic acid; enone; monosaccharide derivative; oxo dicarboxylic acid; pentacyclic triterpenoid; triterpenoid saponin	anti-allergic agent; EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor; human xenobiotic metabolite; plant metabolite; sweetening agent
hydroxysitosterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 7alpha-hydroxy steroid	metabolite; plant metabolite
capsidiol	[no description available]	low	0	eremophilane sesquiterpenoid; octahydronaphthalenes; sesquiterpene phytoalexin	antifungal agent; plant metabolite
phaseollin (isoflavan)	[no description available]	low	0	hydroxyisoflavans	plant metabolite
secoxyloganin	[no description available]	low	0	beta-D-glucoside; dicarboxylic acid monoester; enoate ester; methyl ester; monosaccharide derivative; pyrans; secoiridoid glycoside	anti-allergic agent; antioxidant; plant metabolite
sclareol	[no description available]	low	0	labdane diterpenoid	antifungal agent; antimicrobial agent; apoptosis inducer; fragrance; plant metabolite
butrin	[no description available]	low	0	4'-hydroxyflavanones; flavanone glycoside; monohydroxyflavanone	anti-inflammatory agent; plant metabolite
diplopterol	[no description available]	low	0	hopanoid; pentacyclic triterpenoid; tertiary alcohol	plant metabolite
anacardic acid	[no description available]	low	0	hydroxy monocarboxylic acid; hydroxybenzoic acid	anti-inflammatory agent; antibacterial agent; anticoronaviral agent; apoptosis inducer; EC 2.3.1.48 (histone acetyltransferase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; neuroprotective agent; plant metabolite
confertin	[no description available]	low	0	cyclic ketone; gamma-lactone; organic heterotricyclic compound; pseudoguaianolide	anti-inflammatory agent; metabolite; plant metabolite
pluviatolide	[no description available]	low	0	aromatic ether; benzodioxoles; butan-4-olide; lignan; phenols	plant metabolite
albicanol	[no description available]	low	0	carbobicyclic compound; homoallylic alcohol; primary alcohol; sesquiterpenoid	antifeedant; antifungal agent; antineoplastic agent; fungal metabolite; mammalian metabolite; marine metabolite; plant metabolite
inuviscolide	[no description available]	low	0	gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone; tertiary alcohol	anti-inflammatory agent; plant metabolite
helioxanthin	[no description available]	low	0	benzodioxoles; furonaphthodioxole; lignan	anti-HBV agent; antineoplastic agent; plant metabolite
(2S)-5,7-dihydroxy-6,8-dimethylflavanone	[no description available]	low	0	dihydroxyflavanone	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
medioresinol	[no description available]	low	0	dimethoxybenzene; furofuran; lignan; polyphenol	plant metabolite
5-heptadecylresorcinol	[no description available]	low	0	5-alkylresorcinol	antineoplastic agent; plant metabolite
(+)-epicatechin	[no description available]	low	0	catechin; polyphenol	cyclooxygenase 1 inhibitor; plant metabolite
kobusin	[no description available]	low	0	benzodioxoles; dimethoxybenzene; furofuran; lignan	plant metabolite
nootkatol	[no description available]	low	0	6-isopropenyl-4,4a-dimethyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol	plant metabolite
ergolide	[no description available]	low	0	acetate ester; cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	anti-inflammatory agent; antineoplastic agent; metabolite; NF-kappaB inhibitor; plant metabolite
dihydroresveratrol	[no description available]	low	0	stilbenol	plant metabolite; xenobiotic metabolite
glycitin	[no description available]	low	0	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; methoxyisoflavone; monosaccharide derivative	plant metabolite
benzyl d-glucopyranoside	[no description available]	low	0	benzenes; beta-D-glucoside	plant metabolite
chrysosplenol c	[no description available]	low	0	trihydroxyflavone; trimethoxyflavone	antineoplastic agent; antiviral agent; plant metabolite
5-o-methyllicoricidin	[no description available]	low	0	aromatic ether; hydroxyisoflavans; methoxyisoflavan	antibacterial agent; plant metabolite
pronuciferine	[no description available]	low	0	aromatic ether; cyclic ketone; isoquinoline alkaloid; isoquinolines; organic heterotetracyclic compound	plant metabolite
santonin	[no description available]	low	0	botanical anti-fungal agent; santonin	plant metabolite
sandaracopimaric acid	[no description available]	low	0	monocarboxylic acid; pimarane diterpenoid; tricyclic diterpenoid	plant metabolite
sitosterol, (3beta)-isomer	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; C29-steroid; phytosterols; stigmastane sterol	anticholesteremic drug; antioxidant; mouse metabolite; plant metabolite; sterol methyltransferase inhibitor
erythritol	[no description available]	low	0	butane-1,2,3,4-tetrol	antioxidant; human metabolite; plant metabolite
stigmastanol	[no description available]	low	0	3-hydroxy steroid; phytosterols	anticholesteremic drug; plant metabolite
vincaleukoblastine	[no description available]	low	0	acetate ester; indole alkaloid fundamental parent; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; immunosuppressive agent; microtubule-destabilising agent; plant metabolite
3-octanone	[no description available]	low	0	dialkyl ketone	antifeedant; biomarker; fungal metabolite; human urinary metabolite; insect attractant; plant metabolite; toxin
lanosterol	[no description available]	low	0	14alpha-methyl steroid; 3beta-sterol; tetracyclic triterpenoid	bacterial metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
lupeol	[no description available]	low	0	pentacyclic triterpenoid; secondary alcohol	anti-inflammatory drug; plant metabolite
noscapine	[no description available]	low	0	aromatic ether; benzylisoquinoline alkaloid; cyclic acetal; isobenzofuranone; organic heterobicyclic compound; organic heterotricyclic compound; tertiary amino compound	antineoplastic agent; antitussive; apoptosis inducer; plant metabolite
aromaticin	[no description available]	low	0	cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	anti-inflammatory agent; metabolite; plant metabolite
methyl 3,4-dihydroxybenzoate	[no description available]	low	0	catechols; methyl ester	antioxidant; neuroprotective agent; plant metabolite
2-hydroxy-1,4-benzoxazin-3-one	[no description available]	low	0	benzoxazine; lactam; lactol	allelochemical; plant metabolite
menthofuran	[no description available]	low	0	1-benzofurans; monoterpenoid	nematicide; plant metabolite
lariciresinol	[no description available]	low	0	aromatic ether; lignan; oxolanes; phenols; primary alcohol	antifungal agent; plant metabolite
anthricin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes	antineoplastic agent; apoptosis inducer; plant metabolite
indole-3-acetonitrile	[no description available]	low	0	indoles; nitrile	auxin; human xenobiotic metabolite; plant hormone; plant metabolite
taiwanin c	[no description available]	low	0	benzodioxoles; furonaphthodioxole; lignan	antineoplastic agent; plant metabolite; platelet aggregation inhibitor
sampangine	[no description available]	low	0	alkaloid; organic heterotetracyclic compound	antifungal agent; plant metabolite
isochamaejasmin	[no description available]	low	0	biflavonoid; hydroxyflavone	plant metabolite
norbelladine	[no description available]	low	0	catechols; phenethylamine alkaloid; polyphenol; secondary amino compound	plant metabolite
canavanine	[no description available]	low	0	amino acid zwitterion; non-proteinogenic L-alpha-amino acid	phytogenic insecticide; plant metabolite
raffinose	[no description available]	low	0	raffinose family oligosaccharide; trisaccharide	mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
5-hydroxytryptophan	[no description available]	low	0	5-hydroxytryptophan; amino acid zwitterion; hydroxy-L-tryptophan; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; plant metabolite
theanine	[no description available]	low	0	amino acid zwitterion; N(5)-alkyl-L-glutamine	geroprotector; neuroprotective agent; plant metabolite
ouabain	[no description available]	low	0	11alpha-hydroxy steroid; 14beta-hydroxy steroid; 5beta-hydroxy steroid; alpha-L-rhamnoside; cardenolide glycoside; steroid hormone	anti-arrhythmia drug; cardiotonic drug; EC 2.3.3.1 [citrate (Si)-synthase] inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; ion transport inhibitor; plant metabolite
scopolin	[no description available]	low	0	beta-D-glucoside; coumarins; monosaccharide derivative	plant metabolite
stachyose	[no description available]	low	0	raffinose family oligosaccharide; tetrasaccharide	mouse metabolite; plant metabolite
isomaltulose	[no description available]	low	0	glycosylfructose	animal metabolite; plant metabolite; sweetening agent
discretamine	[no description available]	low	0	berberine alkaloid; organic heterotetracyclic compound	EC 5.99.1.2 (DNA topoisomerase) inhibitor; plant metabolite
mimosine	[no description available]	low	0	4-pyridones; amino acid zwitterion; non-proteinogenic L-alpha-amino acid	EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
pelargonidin	[no description available]	low	0	5-hydroxyanthocyanidin	plant metabolite
(+)-limonene	[no description available]	low	0	limonene	plant metabolite
hygrine	[no description available]	low	0	1-(1-methylpyrrolidin-2-yl)acetone; pyrrolidine alkaloid	plant metabolite
conessine	[no description available]	low	0	steroid alkaloid; tertiary amino compound	antibacterial agent; antimalarial; H3-receptor antagonist; plant metabolite
canaline	[no description available]	low	0	amino acid zwitterion; non-proteinogenic L-alpha-amino acid	antimetabolite; antineoplastic agent; phytogenic insecticide; plant metabolite
norpseudoephedrine	[no description available]	low	0	amphetamines; phenethylamine alkaloid	central nervous system stimulant; plant metabolite; psychotropic drug
sophoranone	[no description available]	low	0	4'-hydroxyflavanones; dihydroxyflavanone	plant metabolite
petunidin	[no description available]	low	0	5-hydroxyanthocyanidin	plant metabolite
glaucarubinone	[no description available]	low	0	carboxylic ester; organic heteropentacyclic compound; quassinoid; secondary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone; tetrol	antimalarial; antineoplastic agent; geroprotector; plant metabolite
helveticoside	[no description available]	low	0	14beta-hydroxy steroid; 5beta-hydroxy steroid; cardenolide glycoside; digitoxoside; monosaccharide derivative; steroid aldehyde; steroid lactone	antineoplastic agent; apoptosis inducer; plant metabolite
ginsenoside re	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; nephroprotective agent; neuroprotective agent; plant metabolite
ginsenoside rf	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; plant metabolite
3-o-(alpha-l-arabinopyranosyl)hederagenin	[no description available]	low	0	alpha-L-arabinopyranoside; hydroxy monocarboxylic acid; monosaccharide derivative; pentacyclic triterpenoid; triterpenoid saponin	plant metabolite
notoginsenoside r1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antioxidant; apoptosis inducer; neuroprotective agent; phytoestrogen; plant metabolite
2-(2-phenylethyl)chromone	[no description available]	low	0	benzenes; chromones	plant metabolite
ferruginol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; meroterpenoid; phenols	antibacterial agent; antineoplastic agent; plant metabolite; protective agent
stevioside	[no description available]	low	0	beta-D-glucoside; bridged compound; diterpene glycoside; ent-kaurane diterpenoid; tetracyclic diterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; hypoglycemic agent; plant metabolite; sweetening agent
lenticin	[no description available]	low	0	amino-acid betaine; indole alkaloid; L-tryptophan derivative	fungal metabolite; plant metabolite; xenobiotic
absynthin	[no description available]	low	0	organic heteroheptacyclic compound; sesquiterpene lactone; triterpenoid	anti-inflammatory agent; plant metabolite
afzelechin	[no description available]	low	0	catechin; tetrahydroxyflavan	EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite
asebogenin	[no description available]	low	0	dihydrochalcones	plant metabolite
lactucin	[no description available]	low	0	azulenofuran; cyclic terpene ketone; enone; primary alcohol; secondary alcohol; sesquiterpene lactone	antimalarial; plant metabolite; sedative
picrotin	[no description available]	low	0	diol; epoxide; gamma-lactone; organic heteropentacyclic compound; picrotoxane sesquiterpenoid; tertiary alcohol	plant metabolite
picrotoxinin	[no description available]	low	0	epoxide; gamma-lactone; organic heteropentacyclic compound; picrotoxane sesquiterpenoid; tertiary alcohol	GABA antagonist; plant metabolite; serotonergic antagonist
solavetivone	[no description available]	low	0	cyclic ketone; sesquiterpenoid; spiro compound	phytoalexin; plant metabolite
thujopsene	[no description available]	low	0	thujopsene	plant metabolite
agnuside	[no description available]	low	0	benzoate ester; beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monosaccharide derivative; phenols; terpene glycoside	anti-inflammatory agent; cyclooxygenase 2 inhibitor; plant metabolite; pro-angiogenic agent
dolichodial	[no description available]	low	0	dialdehyde; iridoid monoterpenoid; olefinic compound	animal metabolite; plant metabolite; volatile oil component
theasinensin a	[no description available]	low	0	biflavonoid; gallate ester; proanthocyanidin	anti-inflammatory agent; anticoronaviral agent; apoptosis inducer; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; melanin synthesis inhibitor; plant metabolite
ammodendrine	[no description available]	low	0	acetamides; N-acylpiperidine; piperidine alkaloid	plant metabolite; teratogenic agent
carpaine	[no description available]	low	0	alkaloid; macrodiolide	cardiovascular drug; plant metabolite
myosmine	[no description available]	low	0	pyridine alkaloid; pyrroline	EC 1.14.14.14 (aromatase) inhibitor; mutagen; plant metabolite
dihydropinosylvin	[no description available]	low	0	diphenylethane; resorcinols	EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
yatein	[no description available]	low	0	benzodioxoles; butan-4-olide; lignan; methoxybenzenes	plant metabolite
solasodine	[no description available]	low	0	alkaloid antibiotic; azaspiro compound; hemiaminal ether; oxaspiro compound; sapogenin; steroid alkaloid	anticonvulsant; antifungal agent; antiinfective agent; antioxidant; antipyretic; antispermatogenic agent; apoptosis inducer; cardiotonic drug; central nervous system depressant; diuretic; immunomodulator; plant metabolite; teratogenic agent
1-alpha-terpineol	[no description available]	low	0	alpha-terpineol	plant metabolite
7-deoxyloganic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monosaccharide derivative; monoterpene glycoside	plant metabolite
epiafzelechin	[no description available]	low	0	catechin	plant metabolite
maleic acid	[no description available]	low	0	butenedioic acid	algal metabolite; mouse metabolite; plant metabolite
farnesol	[no description available]	low	0	farnesol	plant metabolite
resveratrol	[no description available]	low	0	resveratrol	antioxidant; phytoalexin; plant metabolite; quorum sensing inhibitor; radical scavenger
retinol	[no description available]	low	0	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite
oleic acid	[no description available]	low	0	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent
ferulic acid	[no description available]	low	0	ferulic acids	anti-inflammatory agent; antioxidant; apoptosis inhibitor; cardioprotective agent; MALDI matrix material; plant metabolite
cocaine	[no description available]	low	0	benzoate ester; methyl ester; tertiary amino compound; tropane alkaloid	adrenergic uptake inhibitor; central nervous system stimulant; dopamine uptake inhibitor; environmental contaminant; local anaesthetic; mouse metabolite; plant metabolite; serotonin uptake inhibitor; sodium channel blocker; sympathomimetic agent; vasoconstrictor agent; xenobiotic
lycopene	[no description available]	low	0	acyclic carotene	antioxidant; plant metabolite
benzoylecgonine	[no description available]	low	0	benzoate ester; tropane alkaloid	epitope; human xenobiotic metabolite; marine xenobiotic metabolite; plant metabolite
zeatin	[no description available]	low	0	zeatin	plant metabolite
costatolide	[no description available]	low	0	cyclic ether; delta-lactone; organic heterotetracyclic compound; secondary alcohol	HIV-1 reverse transcriptase inhibitor; plant metabolite
euscaphic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid; triol	plant metabolite
cinnamtannin b-1	[no description available]	low	0	proanthocyanidin	cyclooxygenase 2 inhibitor; plant metabolite
meso-dihydroguaiaretic acid	[no description available]	low	0	guaiacols; lignan	plant metabolite
pallidol	[no description available]	low	0	carbopolycyclic compound; polyphenol; stilbenoid	antifungal agent; antioxidant; plant metabolite
egonol	[no description available]	low	0	1-benzofurans; aromatic ether; benzodioxoles; primary alcohol	plant metabolite
23-hydroxytormentic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid; tetrol	anti-inflammatory agent; plant metabolite
riboflavin	[no description available]	low	0	flavin; vitamin B2	anti-inflammatory agent; antioxidant; cofactor; Escherichia coli metabolite; food colouring; fundamental metabolite; human urinary metabolite; mouse metabolite; photosensitizing agent; plant metabolite
sodium benzoate	[no description available]	low	0	organic sodium salt	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
3-mercaptohexanol	[no description available]	low	0	alkanethiol; primary alcohol	flavouring agent; plant metabolite; Saccharomyces cerevisiae metabolite
3'-methoxyflavone	[no description available]	low	0	3'-methoxyflavones	plant metabolite
piperlactam s	[no description available]	low	0	alkaloid; aromatic ether; gamma-lactam; organic heterotetracyclic compound; phenols	anti-inflammatory agent; antioxidant; plant metabolite
piperyline	[no description available]	low	0	benzodioxoles; N-acylpyrrolidine; pyrrolidine alkaloid; tertiary carboxamide	antifungal agent; apoptosis inducer; plant metabolite
crotonic acid	[no description available]	low	0	2-butenoic acid	plant metabolite
rhapontin	[no description available]	low	0	rhaponticin	angiogenesis inhibitor; anti-allergic agent; anti-inflammatory agent; antilipemic drug; antineoplastic agent; apoptosis inducer; EC 2.3.1.85 (fatty acid synthase) inhibitor; hypoglycemic agent; neuroprotective agent; plant metabolite
cinnamaldehyde	[no description available]	low	0	3-phenylprop-2-enal; cinnamaldehydes	antifungal agent; EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor; flavouring agent; hypoglycemic agent; plant metabolite; sensitiser; vasodilator agent
methyl cinnamate	[no description available]	low	0	methyl cinnamate	antibacterial agent; fungal metabolite; nematicide; plant metabolite
2,4-hexadienal	[no description available]	low	0	hexadienal; polyunsaturated fatty aldehyde; volatile organic compound	flavouring agent; plant metabolite
geraniol	[no description available]	low	0	3,7-dimethylocta-2,6-dien-1-ol; monoterpenoid; primary alcohol	allergen; fragrance; plant metabolite; volatile oil component
epipinoresinol	[no description available]	low	0	pinoresinol	marine metabolite; plant metabolite
sinapinic acid	[no description available]	low	0	sinapic acid	MALDI matrix material; plant metabolite
citral	[no description available]	low	0	enal; monoterpenoid; polyprenal	plant metabolite; volatile oil component
piperine	[no description available]	low	0	benzodioxoles; N-acylpiperidine; piperidine alkaloid; tertiary carboxamide	food component; human blood serum metabolite; NF-kappaB inhibitor; plant metabolite
squalene	[no description available]	low	0	triterpene	human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
coumestan	[no description available]	low	0	coumestans; delta-lactone	phytoestrogen; plant metabolite
antofine	[no description available]	low	0	alkaloid antibiotic; alkaloid; aromatic ether; organic heteropentacyclic compound	angiogenesis inhibitor; anti-inflammatory agent; antimicrobial agent; antineoplastic agent; antiviral agent; phytotoxin; plant metabolite
p-hydroxycinnamaldehyde	[no description available]	low	0	cinnamaldehydes	apoptosis inducer; EC 1.14.13.39 (nitric oxide synthase) inhibitor; plant metabolite
n-methylproline	[no description available]	low	0	L-alpha-amino acid zwitterion; L-proline derivative; tertiary amino compound	human metabolite; plant metabolite
vedelianin	[no description available]	low	0	cyclic ether; organic heterotricyclic compound; resorcinols; stilbenoid	antineoplastic agent; plant metabolite
pedilstatin	[no description available]	low	0	acetate ester; phorbol ester; primary allylic alcohol	plant metabolite
nerol	[no description available]	low	0	3,7-dimethylocta-2,6-dien-1-ol	fragrance; plant metabolite; volatile oil component
cannabidiol	[no description available]	low	0	olefinic compound; phytocannabinoid; resorcinols	antimicrobial agent; plant metabolite
amygdalin	[no description available]	low	0	amygdalin	antineoplastic agent; apoptosis inducer; plant metabolite
3,3',4,5'-tetrahydroxystilbene	[no description available]	low	0	catechols; polyphenol; resorcinols; stilbenol	antineoplastic agent; apoptosis inducer; geroprotector; hypoglycemic agent; plant metabolite; protein kinase inhibitor; tyrosine kinase inhibitor
dehydrovomifoliol	[no description available]	low	0	dehydrovomifoliol	plant metabolite
isoeugenol	[no description available]	low	0	isoeugenol	plant metabolite
cotinine	[no description available]	low	0	N-alkylpyrrolidine; pyridines; pyrrolidin-2-ones; pyrrolidine alkaloid	antidepressant; biomarker; human xenobiotic metabolite; plant metabolite
huperzine a	[no description available]	low	0	organic heterotricyclic compound; primary amino compound; pyridone; sesquiterpene alkaloid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; neuroprotective agent; nootropic agent; plant metabolite
nootkatone	[no description available]	low	0	carbobicyclic compound; enone; sesquiterpenoid	fragrance; insect repellent; plant metabolite
geranyl acetate	[no description available]	low	0	acetate ester; monoterpenoid	plant metabolite
coniferyl alcohol	[no description available]	low	0	guaiacols; phenylpropanoid	animal metabolite; monolignol; mouse metabolite; pheromone; plant metabolite; volatile oil component
geranylacetone	[no description available]	low	0	monoterpene ketone	flavouring agent; fragrance; plant metabolite; volatile oil component
aurapten	[no description available]	low	0	coumarins; monoterpenoid	antihypertensive agent; antineoplastic agent; antioxidant; apoptosis inducer; dopaminergic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; gamma-secretase modulator; gastrointestinal drug; hepatoprotective agent; matrix metalloproteinase inhibitor; neuroprotective agent; plant metabolite; PPARalpha agonist; vulnerary
goitrin	[no description available]	low	0	5-ethenyl-1,3-oxazolidine-2-thione	antiviral agent; plant metabolite
7-deacetylgedunin	[no description available]	low	0	cyclic terpene ketone; delta-lactone; enone; epoxide; furans; limonoid; pentacyclic triterpenoid	anti-inflammatory agent; antimalarial; metabolite; plant metabolite
manool	[no description available]	low	0	labdane diterpenoid; tertiary alcohol	antibacterial agent; antineoplastic agent; plant metabolite
2-oxindole-3-acetic acid	[no description available]	low	0	indole-3-acetic acids; monocarboxylic acid; oxindoles	plant metabolite
bigelovin	[no description available]	low	0	acetate ester; cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	antineoplastic agent; apoptosis inducer; immunomodulator; plant metabolite
cyclanoline	[no description available]	low	0	berberine alkaloid; quaternary ammonium ion	EC 3.1.1.7 (acetylcholinesterase) inhibitor; plant metabolite
sideroxylin	[no description available]	low	0	dihydroxyflavone; monomethoxyflavone	plant metabolite
ladanein	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	antiviral agent; plant metabolite; radical scavenger
t-muurolol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	bacterial metabolite; fungicide; marine metabolite; plant metabolite; volatile oil component
alpha-carotene	[no description available]	low	0	carotenoid beta-end derivative; cyclic carotene	plant metabolite; provitamin A
citramalate	[no description available]	low	0	dicarboxylic acid dianion	human metabolite; plant metabolite
fraxin	[no description available]	low	0	aromatic ether; beta-D-glucoside; hydroxycoumarin	anti-inflammatory agent; hepatoprotective agent; plant metabolite
decaprenoic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; methyl-branched fatty acid; monoterpenoid; polyunsaturated fatty acid	antifungal agent; EC 1.14.18.1 (tyrosinase) inhibitor; melanin synthesis inhibitor; pheromone; plant metabolite
gallocatechin-3-gallate	[no description available]	low	0	catechin; gallate ester; polyphenol	plant metabolite
coniferin	[no description available]	low	0	aromatic ether; cinnamyl alcohol beta-D-glucoside; monosaccharide derivative	plant metabolite
gibberellin a1	[no description available]	low	0	C19-gibberellin; gibberellin monocarboxylic acid; lactone	plant metabolite
leukotriene a4	[no description available]	low	0	epoxy fatty acid; leukotriene; long-chain fatty acid; oxylipin; polyunsaturated fatty acid	human metabolite; mouse metabolite; plant metabolite
sinapine	[no description available]	low	0	acylcholine	antioxidant; photosynthetic electron-transport chain inhibitor; plant metabolite
trans-phytol	[no description available]	low	0	diterpenoid; long-chain primary fatty alcohol	algal metabolite; plant metabolite; schistosomicide drug
linoleic acid	[no description available]	low	0	octadecadienoic acid; omega-6 fatty acid	algal metabolite; Daphnia galeata metabolite; plant metabolite
quercitrin	[no description available]	low	0	alpha-L-rhamnoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	antileishmanial agent; antioxidant; EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
scopoletin	[no description available]	low	0	hydroxycoumarin	plant growth regulator; plant metabolite
beta carotene	[no description available]	low	0	carotenoid beta-end derivative; cyclic carotene	antioxidant; biological pigment; cofactor; ferroptosis inhibitor; human metabolite; mouse metabolite; plant metabolite; provitamin A
leukotriene b4	[no description available]	low	0	dihydroxy monocarboxylic acid; hydroxy polyunsaturated fatty acid; leukotriene; long-chain fatty acid	human metabolite; mouse metabolite; plant metabolite; vasoconstrictor agent
coniferaldehyde	[no description available]	low	0	cinnamaldehydes; guaiacols; phenylpropanoid	antifungal agent; plant metabolite
herbacetin	[no description available]	low	0	7-hydroxyflavonol; pentahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antilipemic drug; antineoplastic agent; apoptosis inducer; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; plant metabolite
5'-o-caffeoylquinic acid	[no description available]	low	0	cinnamate ester; cyclitol carboxylic acid	plant metabolite
ayanin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
apiin	[no description available]	low	0	beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
(all-e) phytoene	[no description available]	low	0	phytoene	plant metabolite
vitamin d 2	[no description available]	low	0	hydroxy seco-steroid; seco-ergostane; vitamin D	bone density conservation agent; nutraceutical; plant metabolite; rodenticide
stigmasterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; phytosterols; stigmastane sterol	plant metabolite
sinapaldehyde	[no description available]	low	0	cinnamaldehydes; dimethoxybenzene; phenols	antifungal agent; plant metabolite
3-methylkaempferol	[no description available]	low	0	monomethoxyflavone; trihydroxyflavone	plant metabolite
abscisic acid	[no description available]	low	0	2-cis-abscisic acid	plant hormone; plant metabolite
senecionine	[no description available]	low	0	lactone; pyrrolizidine alkaloid; tertiary alcohol	plant metabolite
gamma-linolenic acid	[no description available]	low	0	linolenic acid; omega-6 fatty acid	human metabolite; mouse metabolite; plant metabolite
petroselinic acid	[no description available]	low	0	octadec-6-enoic acid	plant metabolite
cyclobenzaprine	[no description available]	low	0	9,11,13-octadecatrienoic acid	antineoplastic agent; plant metabolite
jasmonic acid	[no description available]	low	0	oxo monocarboxylic acid	jasmonates; plant metabolite
2-hexenal, z-isomer	[no description available]	low	0	2-hexenal	antibacterial agent; flavouring agent; plant metabolite
aureusidin	[no description available]	low	0	hydroxyaurone	plant metabolite
butein	[no description available]	low	0	chalcones; polyphenol	antineoplastic agent; antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor; geroprotector; hypoglycemic agent; plant metabolite; radiosensitizing agent; tyrosine kinase inhibitor
antheraxanthin	[no description available]	low	0	epoxycarotenol	biological pigment; marine metabolite; plant metabolite
astaxanthine	[no description available]	low	0	carotenol; carotenone	animal metabolite; anticoagulant; antioxidant; food colouring; plant metabolite
capsanthin	[no description available]	low	0	carotenone	plant metabolite
gardenia yellow	[no description available]	low	0	diester; disaccharide derivative; diterpenoid	antioxidant; food colouring; histological dye; plant metabolite
cryptoxanthins	[no description available]	low	0	carotenol	antioxidant; biomarker; plant metabolite; provitamin A
lutein	[no description available]	low	0	carotenol	food colouring; plant metabolite
hispidol	[no description available]	low	0	hydroxyaurone	plant metabolite
isobutrin	[no description available]	low	0	beta-D-glucoside; chalcones; monosaccharide derivative; phenols	anti-inflammatory agent; hepatoprotective agent; plant metabolite
cassaine	[no description available]	low	0	enoate ester; organic hydroxy compound; tertiary amino compound; tricyclic diterpenoid	antihypertensive agent; cardiotonic drug; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; local anaesthetic; plant metabolite; poison
okanin	[no description available]	low	0	benzenetriol; chalcones	plant metabolite
cucurbitacin i	[no description available]	low	0	cucurbitacin; tertiary alpha-hydroxy ketone	antineoplastic agent; plant metabolite
brassicasterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols	algal metabolite; animal metabolite; biomarker; EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor; human metabolite; marine metabolite; plant metabolite; sterol biosynthesis inhibitor
harman	[no description available]	low	0	harmala alkaloid; indole alkaloid fundamental parent; indole alkaloid	anti-HIV agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
esculetin	[no description available]	low	0	hydroxycoumarin	antioxidant; plant metabolite; ultraviolet filter
7-hydroxycoumarin	[no description available]	low	0	hydroxycoumarin	fluorescent probe; food component; plant metabolite
eupatolide	[no description available]	low	0	gamma-lactone; germacranolide; homoallylic alcohol; secondary alcohol	antineoplastic agent; plant metabolite
petasin	[no description available]	low	0	alicyclic ketone; enoate ester; enone; sesquiterpenoid	anti-allergic agent; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator; plant metabolite; vasodilator agent
oleuropein	[no description available]	low	0	beta-D-glucoside; catechols; diester; methyl ester; pyrans; secoiridoid glycoside	anti-inflammatory agent; antihypertensive agent; antineoplastic agent; antioxidant; apoptosis inducer; NF-kappaB inhibitor; nutraceutical; plant metabolite; radical scavenger
apigenin dimethylether	[no description available]	low	0	dimethoxyflavone; monohydroxyflavone	plant metabolite
axillarin	[no description available]	low	0	dimethoxyflavone; tetrahydroxyflavone	plant metabolite
azaleatin	[no description available]	low	0	7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone	plant metabolite
chrysosplenetin b	[no description available]	low	0	dihydroxyflavone; tetramethoxyflavone	antiviral agent; plant metabolite
gossypin	[no description available]	low	0	7-hydroxyflavonol; glycosyloxyflavone; monosaccharide derivative; pentahydroxyflavone	neuroprotective agent; plant metabolite
hispidulin	[no description available]	low	0	monomethoxyflavone; trihydroxyflavone	anti-inflammatory agent; anticonvulsant; antineoplastic agent; antioxidant; apoptosis inducer; plant metabolite
euxanthone	[no description available]	low	0	phenols; xanthones	metabolite; plant metabolite
gartanin	[no description available]	low	0	polyphenol; xanthones	antineoplastic agent; plant metabolite
gentiacaulein	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
gentisein	[no description available]	low	0	polyphenol; xanthones	plant metabolite
gentisin	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
isogentisin	[no description available]	low	0	aromatic ether; polyphenol; xanthones	EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
mangostin	[no description available]	low	0	aromatic ether; phenols; xanthones	antimicrobial agent; antineoplastic agent; antioxidant; plant metabolite
1,8-dihydroxy-3,7-dimethoxyxanthone	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
norathyriol	[no description available]	low	0	polyphenol; xanthones	antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor; plant metabolite
1,2,8-trihydroxy-6-methoxyxanthone	[no description available]	low	0	aromatic ether; polyphenol; xanthones	antioxidant; plant metabolite
kuwanon g	[no description available]	low	0	resorcinols; tetrahydroxyflavone	anti-inflammatory agent; plant metabolite
kuwanon h	[no description available]	low	0	resorcinols; tetrahydroxyflavone	plant metabolite
morusin	[no description available]	low	0	extended flavonoid; trihydroxyflavone	antineoplastic agent; plant metabolite
myricitrin	[no description available]	low	0	alpha-L-rhamnoside; glycosyloxyflavone; monosaccharide derivative; pentahydroxyflavone	anti-allergic agent; EC 1.14.13.39 (nitric oxide synthase) inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; plant metabolite
pachypodol	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	antiemetic; plant metabolite
quercetagetin	[no description available]	low	0	flavonols; hexahydroxyflavone	antioxidant; antiviral agent; plant metabolite
robinin	[no description available]	low	0	dihydroxyflavone; glycosyloxyflavone	plant metabolite
santin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
coumestrol	[no description available]	low	0	coumestans; delta-lactone; polyphenol	anti-inflammatory agent; antioxidant; plant metabolite
pterostilbene	[no description available]	low	0	diether; methoxybenzenes; stilbenol	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; neuroprotective agent; neurotransmitter; plant metabolite; radical scavenger
genistein-8-c-glucoside	[no description available]	low	0	7-hydroxyisoflavones; C-glycosyl compound	plant metabolite
5-o-caffeoylshikimic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; carboxylic ester; catechols; cyclohexenecarboxylic acid	plant metabolite
cynarine	[no description available]	low	0	alkyl caffeate ester; quinic acid	plant metabolite
rosmarinic acid	[no description available]	low	0	rosmarinic acid	geroprotector; plant metabolite
acteoside	[no description available]	low	0	catechols; cinnamate ester; disaccharide derivative; glycoside; polyphenol	anti-inflammatory agent; antibacterial agent; antileishmanial agent; neuroprotective agent; plant metabolite
orobol	[no description available]	low	0	7-hydroxyisoflavones	anti-inflammatory agent; fungal metabolite; plant metabolite; radical scavenger
psoralidin	[no description available]	low	0	coumestans; delta-lactone; polyphenol	estrogen receptor agonist; plant metabolite
puerarin	[no description available]	low	0	C-glycosyl compound; hydroxyisoflavone	plant metabolite
maytansine	[no description available]	low	0	alpha-amino acid ester; carbamate ester; epoxide; maytansinoid; organic heterotetracyclic compound; organochlorine compound	antimicrobial agent; antimitotic; antineoplastic agent; plant metabolite; tubulin modulator
ellagic acid	[no description available]	low	0	catechols; cyclic ketone; lactone; organic heterotetracyclic compound; polyphenol	antioxidant; EC 1.14.18.1 (tyrosinase) inhibitor; EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor; EC 2.4.1.1 (glycogen phosphorylase) inhibitor; EC 2.5.1.18 (glutathione transferase) inhibitor; EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor; EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor; EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; food additive; fungal metabolite; geroprotector; plant metabolite; skin lightening agent
savinin	[no description available]	low	0	benzodioxoles; gamma-lactone; lignan	anti-inflammatory agent; anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; plant metabolite; T-cell proliferation inhibitor
tectochrysin	[no description available]	low	0	monohydroxyflavone; monomethoxyflavone	antidiarrhoeal drug; antineoplastic agent; plant metabolite
2'-hydroxygenistein	[no description available]	low	0	hydroxyisoflavone	plant metabolite
cinnamyl acetate	[no description available]	low	0	acetate ester	plant metabolite
vitexin rhamnoside	[no description available]	low	0	C-glycosyl compound; disaccharide derivative; trihydroxyflavone	plant metabolite
kaempferol 3-o-sophoroside	[no description available]	low	0	sophoroside; trihydroxyflavone	plant metabolite
quercetin-3-o-sophoroside	[no description available]	low	0	sophoroside; tetrahydroxyflavone	antioxidant; plant metabolite
ethyl linoleate	[no description available]	low	0	long-chain fatty acid ethyl ester	anti-inflammatory agent; plant metabolite
plaunotol	[no description available]	low	0	diterpenoid; primary alcohol	anti-ulcer drug; antibacterial agent; antineoplastic agent; apoptosis inducer; nephroprotective agent; plant metabolite; vulnerary
sofalcone	[no description available]	low	0	aromatic ether; chalcones; monocarboxylic acid	anti-ulcer drug; antibacterial agent; gastrointestinal drug; plant metabolite
xanthoxin	[no description available]	low	0	apo carotenoid sesquiterpenoid; enal	plant growth retardant; plant metabolite
tocotrienol, alpha	[no description available]	low	0	tocotrienol; vitamin E	ferroptosis inhibitor; human metabolite; neuroprotective agent; plant metabolite
tocotrienol, beta	[no description available]	low	0	tocotrienol; vitamin E	antineoplastic agent; apoptosis inducer; plant metabolite
gamma-tocotrienol	[no description available]	low	0	tocotrienol; vitamin E	antineoplastic agent; antioxidant; apoptosis inducer; hepatoprotective agent; plant metabolite; radiation protective agent
tocotrienol, delta	[no description available]	low	0	tocotrienol; vitamin E	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bone density conservation agent; NF-kappaB inhibitor; plant metabolite; radiation protective agent; Saccharomyces cerevisiae metabolite
4-hydroxychalcone	[no description available]	low	0	chalcones; phenols	antihypertensive agent; plant metabolite
9-hydroxy-10,12-octadecadienoic acid	[no description available]	low	0	HODE; octadecadienoic acid	human metabolite; metabolite; mouse metabolite; plant metabolite
2-heptenal	[no description available]	low	0	enal; medium-chain fatty aldehyde; monounsaturated fatty aldehyde	plant metabolite; uremic toxin
2-nonenal, (trans)-isomer	[no description available]	low	0	enal; medium-chain fatty aldehyde; monounsaturated fatty aldehyde	plant metabolite
oleylamide	[no description available]	low	0	primary fatty amide	human metabolite; plant metabolite
1-monooleoyl-rac-glycerol	[no description available]	low	0	1-acylglycerol 18:1; monooleoylglycerol	plant metabolite
monolinolein	[no description available]	low	0	1-acylglycerol 18:2; rac-1-monoacylglycerol	antiviral agent; human metabolite; plant metabolite
methyl linoleate	[no description available]	low	0	fatty acid methyl ester	plant metabolite
vitamin k 1	[no description available]	low	0	phylloquinones; vitamin K	cofactor; human metabolite; plant metabolite
morphine	[no description available]	low	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic
delta(3)-hexadecenoic acid	[no description available]	low	0	hexadecenoic acid	plant metabolite
stearidonic acid	[no description available]	low	0	long-chain fatty acid; octadecatetraenoic acid; omega-3 fatty acid	Daphnia galeata metabolite; mouse metabolite; plant metabolite
juniperonic acid	[no description available]	low	0	icosatetraenoic acid	plant metabolite
casticin	[no description available]	low	0	dihydroxyflavone; tetramethoxyflavone	apoptosis inducer; plant metabolite
rosmarinic acid	[no description available]	low	0	carboxylic ester; monocarboxylic acid; phenylpropanoid; polyphenol	antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite; serine proteinase inhibitor
cannabigerol	[no description available]	low	0	phytocannabinoid; resorcinols	anti-inflammatory agent; antibacterial agent; antioxidant; appetite enhancer; cannabinoid receptor agonist; neuroprotective agent; plant metabolite
centaureidin	[no description available]	low	0	trihydroxyflavone; trimethoxyflavone	antineoplastic agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; plant metabolite
cinnamyl alcohol	[no description available]	low	0	cinnamyl alcohol	plant metabolite
7-demethylsuberosin	[no description available]	low	0	hydroxycoumarin	plant metabolite
kaempferol 3-o-rhamnoside	[no description available]	low	0	glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	anti-inflammatory agent; antibacterial agent; plant metabolite
syringin	[no description available]	low	0	beta-D-glucoside; dimethoxybenzene; monosaccharide derivative; primary alcohol	hepatoprotective agent; plant metabolite
3,3'-di-o-methylquercetin	[no description available]	low	0	3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone	antibacterial agent; antineoplastic agent; apoptosis inducer; plant metabolite
glycitein	[no description available]	low	0	7-hydroxyisoflavone; methoxyisoflavone	fungal metabolite; phytoestrogen; plant metabolite
quadrangularin a	[no description available]	low	0	indanes; polyphenol; stilbenoid	antioxidant; plant metabolite
isoginkgetin	[no description available]	low	0	aromatic ether; biflavonoid	antineoplastic agent; EC 3.4.24.35 (gelatinase B) inhibitor; plant metabolite
isomangiferin	[no description available]	low	0	C-glycosyl compound; polyphenol; xanthones	anti-HSV-1 agent; plant metabolite
isosalipurposide	[no description available]	low	0	beta-D-glucoside; chalcones; monosaccharide derivative; resorcinols	antioxidant; plant metabolite
kaempferol-3-o-rutinoside	[no description available]	low	0	disaccharide derivative; kaempferol O-glucoside; rutinoside; trihydroxyflavone	metabolite; plant metabolite; radical scavenger
luteolin 4'-o-glucoside	[no description available]	low	0	beta-D-glucoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	plant metabolite
methyl linolenate	[no description available]	low	0	fatty acid methyl ester	insect attractant; plant metabolite
3'-o-methylorobol	[no description available]	low	0	hydroxyisoflavone; methoxyisoflavone	plant metabolite
1,3,6-trihydroxy-2-methyl-9,10-anthraquinone	[no description available]	low	0	trihydroxyanthraquinone	plant metabolite
cudraflavone c	[no description available]	low	0	tetrahydroxyflavone	antibacterial agent; antineoplastic agent; plant metabolite
muromonab-cd3	[no description available]	low	0	extended flavonoid; pyranochromane; trihydroxyflavone	anti-inflammatory agent; plant metabolite
beta-ocimene	[no description available]	low	0	beta-ocimene	plant metabolite
ombuine	[no description available]	low	0	dimethoxyflavone; flavonols; trihydroxyflavone	anti-inflammatory agent; plant metabolite
osthenol	[no description available]	low	0	hydroxycoumarin	antifungal agent; plant metabolite
tiliroside	[no description available]	low	0	cinnamate ester; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	plant metabolite
spiraeoside	[no description available]	low	0	beta-D-glucoside; flavonols; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antineoplastic agent; antioxidant; plant metabolite
rhamnazin	[no description available]	low	0	aromatic ether; dimethoxyflavone; phenols; trihydroxyflavone	antineoplastic agent; plant metabolite
kaempferol-7-methyl ether	[no description available]	low	0	flavonols; monomethoxyflavone; trihydroxyflavone	plant metabolite
oridonin	[no description available]	low	0	cyclic hemiketal; enone; ent-kaurane diterpenoid; organic heteropentacyclic compound; secondary alcohol	angiogenesis inhibitor; anti-asthmatic agent; antibacterial agent; antineoplastic agent; apoptosis inducer; plant metabolite
7,8-dimethylalloxazine	[no description available]	low	0	7,8-dimethylbenzo[g]pteridine-2,4-dione	plant metabolite
ergothioneine	[no description available]	low	0	1,3-dihydroimidazole-2-thiones; amino-acid betaine; L-histidine derivative; sulfur-containing amino acid	antioxidant; chelator; fungal metabolite; plant metabolite; xenobiotic metabolite
ermanin	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	anti-inflammatory agent; antimycobacterial drug; antineoplastic agent; apoptosis inducer; plant metabolite
5-hydroxy-3,3',4',7-tetramethoxyflavone	[no description available]	low	0	3'-methoxyflavones; monohydroxyflavone; tetramethoxyflavone	plant metabolite
methyl 2,5-dihydroxycinnamate	[no description available]	low	0	cinnamate ester; hydroquinones; methyl ester	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; geroprotector; human urinary metabolite; plant metabolite
methyl ferulate	[no description available]	low	0	cinnamate ester; guaiacols; methyl ester	plant metabolite
lichexanthone	[no description available]	low	0	aromatic ether; phenols; xanthones	plant metabolite
glyceryl behenate	[no description available]	low	0	1-monoglyceride; fatty acid ester	antineoplastic agent; plant metabolite
ethyl oleate	[no description available]	low	0	long-chain fatty acid ethyl ester	acaricide; plant metabolite
2-pentenal	[no description available]	low	0	2-pentenal	plant metabolite
erucyl amide	[no description available]	low	0	13-docosenamide	EC 3.1.1.7 (acetylcholinesterase) inhibitor; human metabolite; mammalian metabolite; plant metabolite; rat metabolite
beta-damascenone	[no description available]	low	0	apo carotenoid monoterpenoid; cyclic monoterpene ketone; enone	fragrance; plant metabolite; volatile oil component
piperic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; benzodioxoles	plant metabolite
pipercallosidine	[no description available]	low	0	alkaloid; benzodioxoles; enamide; secondary carboxamide	apoptosis inducer; metabolite; plant metabolite
dehydrodiconiferyl alcohol	[no description available]	low	0	1-benzofurans; guaiacols; guaiacyl lignin; primary alcohol	anti-inflammatory agent; plant metabolite
noreugenin	[no description available]	low	0	chromones; resorcinols	plant metabolite
decussatin	[no description available]	low	0	aromatic ether; phenols; xanthones	plant metabolite
ecdysterone	[no description available]	low	0	14alpha-hydroxy steroid; 20-hydroxy steroid; 22-hydroxy steroid; 25-hydroxy steroid; 2beta-hydroxy steroid; 3beta-sterol; ecdysteroid; phytoecdysteroid	animal metabolite; plant metabolite
beta-aminopropionitrile fumarate (2:1)	[no description available]	low	0	fumarate salt	antineoplastic agent; antirheumatic drug; collagen cross-linking inhibitor; plant metabolite
gamma-mangostin	[no description available]	low	0	phenols; xanthones	antineoplastic agent; plant metabolite; protein kinase inhibitor
5,4'-dihydroxy-7,3'-dimethoxyflavone	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	anti-allergic agent; anti-inflammatory agent; antibacterial agent; antioxidant; melanin synthesis inhibitor; plant metabolite
1,7-dihydroxy-4-methoxyxanthone	[no description available]	low	0	aromatic ether; phenols; xanthones	metabolite; plant metabolite
tetrahydroxycurcumin	[no description available]	low	0	beta-diketone; catechols; diarylheptanoid; enone; polyphenol	anti-inflammatory agent; neuroprotective agent; plant metabolite
zerumbone	[no description available]	low	0	cyclic ketone; sesquiterpenoid	anti-inflammatory agent; glioma-associated oncogene inhibitor; plant metabolite
solanesol	[no description available]	low	0	nonaprenol; primary alcohol	plant metabolite
quercetin 3-sambubioside	[no description available]	low	0	disaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antioxidant; plant metabolite
baohuoside i	[no description available]	low	0	glycosyloxyflavone	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; plant metabolite
ochnaflavone	[no description available]	low	0	aromatic ether; biflavonoid; hydroxyflavone	anti-inflammatory agent; antiatherogenic agent; antibacterial agent; EC 3.1.1.4 (phospholipase A2) inhibitor; leukotriene antagonist; plant metabolite
isowighteone	[no description available]	low	0	7-hydroxyisoflavones	plant metabolite
triolein	[no description available]	low	0	triglyceride	Caenorhabditis elegans metabolite; plant metabolite
resiniferatoxin	[no description available]	low	0	carboxylic ester; diterpenoid; enone; monomethoxybenzene; organic heteropentacyclic compound; ortho ester; phenols; tertiary alpha-hydroxy ketone	analgesic; neurotoxin; plant metabolite; TRPV1 agonist
lyoniside	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; steroid saponin	plant metabolite
4-hydroxycordoin	[no description available]	low	0	aromatic ether; chalcones; polyphenol	anti-inflammatory agent; antibacterial agent; plant metabolite
n-feruloylserotonin	[no description available]	low	0	aromatic ether; cinnamamides; hydroxyindoles; phenols; secondary carboxamide	plant metabolite
zosteric acid	[no description available]	low	0	aryl sulfate; cinnamic acids	antifouling biocide; plant metabolite
eupomatenoid 6	[no description available]	low	0	benzofurans; phenols	anti-inflammatory agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; NF-kappaB inhibitor; plant metabolite
amaranthin betacyanin	[no description available]	low	0	disaccharide derivative; indoles; olefinic compound; tetrahydropyridine	biological pigment; plant metabolite
mevalonolactone	[no description available]	low	0	4-hydroxy-4-methyloxan-2-one	fungal metabolite; plant metabolite
coronardine	[no description available]	low	0	alkaloid ester; methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound	antileishmanial agent; antineoplastic agent; apoptosis inducer; plant metabolite
columbianadin	[no description available]	low	0	alpha,beta-unsaturated carboxylic ester; furanocoumarin	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; hepatoprotective agent; plant metabolite; rat metabolite
germacrone	[no description available]	low	0	germacrane sesquiterpenoid; olefinic compound	androgen antagonist; anti-inflammatory agent; antifeedant; antifungal agent; antimicrobial agent; antineoplastic agent; antioxidant; antitussive; antiviral agent; apoptosis inducer; autophagy inducer; hepatoprotective agent; insecticide; neuroprotective agent; plant metabolite; volatile oil component
salannin	[no description available]	low	0	acetate ester; furans; limonoid; methyl ester; organic heteropentacyclic compound	antifeedant; insect growth regulator; plant metabolite
thunberginol f	[no description available]	low	0	catechols; gamma-lactone; isobenzofuranone	metabolite; plant metabolite
9-hydroxy-10,12,15-octadecatrienoic acid	[no description available]	low	0	9-HOTrE	plant metabolite
valerenic acid	[no description available]	low	0	carbobicyclic compound; monocarboxylic acid; sesquiterpenoid	GABA modulator; plant metabolite; sedative; volatile oil component
zeatin riboside	[no description available]	low	0	9-ribosylzeatin; nucleoside analogue	cytokinin; plant metabolite
acuminatin	[no description available]	low	0	1-benzofurans; dimethoxybenzene; neolignan; olefinic compound; ring assembly	fungal metabolite; plant metabolite
cucurbitacin I 2-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; cucurbitacin; monosaccharide derivative; tertiary alpha-hydroxy ketone; triterpenoid saponin	plant metabolite
perflubron	[no description available]	low	0	2-acyl-4-prenylphloroglucinol; chalcones	plant metabolite
tuberonic acid	[no description available]	low	0	cyclopentanones; homoallylic alcohol; oxo monocarboxylic acid; primary alcohol	jasmonates; plant metabolite
salvianolic acid B	[no description available]	low	0	1-benzofurans; catechols; dicarboxylic acid; enoate ester; polyphenol	anti-inflammatory agent; antidepressant; antineoplastic agent; antioxidant; apoptosis inducer; autophagy inhibitor; cardioprotective agent; hepatoprotective agent; hypoglycemic agent; neuroprotective agent; osteogenesis regulator; plant metabolite
trilobatin	[no description available]	low	0	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	anti-inflammatory agent; antioxidant; plant metabolite; sweetening agent
2',4',6'-trihydroxychalcone	[no description available]	low	0	chalcones	antifungal agent; plant metabolite
beta-tocopherol	[no description available]	low	0	tocopherol; vitamin E	food component; plant metabolite
nyasol	[no description available]	low	0	1,3-bis(p-hydroxyphenyl)pentane-1,4-diene	plant metabolite
ginsenoside rb2	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antiviral agent; hypoglycemic agent; plant metabolite
yunaconitine	[no description available]	low	0	acetate ester; aromatic ether; benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound	antifeedant; human urinary metabolite; phytotoxin; plant metabolite; xenobiotic
3-tyrosine	[no description available]	low	0	hydroxyphenylalanine; L-alpha-amino acid zwitterion; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; phenols	plant metabolite
alpha-solanine	[no description available]	low	0	glycoalkaloid; organic heterohexacyclic compound; steroid saponin; trisaccharide derivative	antineoplastic agent; apoptosis inducer; phytotoxin; plant metabolite
3-O-feruloyl-D-quinic acid	[no description available]	low	0	enoate ester; quinic acid	plant metabolite
ginsenoside f1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; 6alpha-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	apoptosis inhibitor; plant metabolite
capsiate	[no description available]	low	0	carboxylic ester; monomethoxybenzene; phenols	angiogenesis inhibitor; anti-allergic agent; anti-inflammatory agent; antioxidant; capsaicin receptor agonist; hypoglycemic agent; plant metabolite
p-coumaric acid glucoside	[no description available]	low	0	4-O-beta-D-glucosyl-4-coumaric acid	plant metabolite
ginsenoside m1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	anti-allergic agent; anti-inflammatory agent; antineoplastic agent; hepatoprotective agent; plant metabolite
nicotianamine	[no description available]	low	0	amino acid zwitterion; nicotianamine	chelator; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; plant metabolite
ginsenoside rb1	[no description available]	low	0	ginsenoside; glycoside; tetracyclic triterpenoid	anti-inflammatory drug; anti-obesity agent; apoptosis inhibitor; neuroprotective agent; plant metabolite; radical scavenger
6''-o-malonyldaidzin	[no description available]	low	0	glycosyloxyisoflavone; hydroxyisoflavone; malonate ester; monosaccharide derivative	plant metabolite
ginsenoside f2	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; plant metabolite
ginsenoside rg3	[no description available]	low	0	ginsenoside; glycoside; tetracyclic triterpenoid	angiogenesis modulating agent; antineoplastic agent; apoptosis inducer; plant metabolite
4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acid	[no description available]	low	0	11-oxo steroid; 3-oxo steroid; 7-oxo steroid; ergostanoid; monocarboxylic acid; steroid acid	anti-inflammatory agent; antineoplastic agent; plant metabolite
hetacillin	[no description available]	low	0	guaiacols; lignan; oxolanes; polyphenol; tetrol	plant metabolite
3-epi-fagomine	[no description available]	low	0	amino monosaccharide; hydroxypiperidine; primary alcohol; secondary alcohol; secondary amino compound; triol	EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor; EC 3.2.1.23 (beta-galactosidase) inhibitor; plant metabolite
akuammicine	[no description available]	low	0	methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	plant metabolite
demethylzeylasteral	[no description available]	low	0	arenecarbaldehyde; benzenediols; carbopolycyclic compound; cyclic ketone; enone; oxo monocarboxylic acid	anti-inflammatory agent; EC 2.4.1.17 (glucuronosyltransferase) inhibitor; immunosuppressive agent; nephroprotective agent; plant metabolite
alpha-cadinol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	fungicide; plant metabolite; volatile oil component
11-hydroxysugiol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; catechols; cyclic terpene ketone; meroterpenoid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant metabolite
triptohypol C	[no description available]	low	0	benzenediols; monocarboxylic acid; pentacyclic triterpenoid	apoptosis inducer; plant metabolite
trilobacin	[no description available]	low	0	butenolide; polyketide; triol	antineoplastic agent; plant metabolite
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone	[no description available]	low	0	chalcones; monomethoxybenzene; resorcinols	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one	[no description available]	low	0	diarylheptanoid; enone; phenols	plant metabolite
6-deacetylnimbin	[no description available]	low	0	cyclic terpene ketone; diester; enone; furans; limonoid; methyl ester; tetracyclic triterpenoid	antifeedant; insect growth regulator; plant metabolite
1,7-bis(4-hydroxyphenyl)hepta-4E-6E-dien-3-one	[no description available]	low	0	diarylheptanoid; enone; phenols	plant metabolite
2,3-dihydro-3beta-methoxy withaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; secondary alcohol; withanolide	metabolite; plant metabolite
azadirone	[no description available]	low	0	acetate ester; cyclic terpene ketone; furans; limonoid; tetracyclic triterpenoid	antineoplastic agent; antiplasmodial drug; plant metabolite
dihydroartemisinic acid	[no description available]	low	0	carbobicyclic compound; monocarboxylic acid; octahydronaphthalenes; sesquiterpenoid	plant metabolite
atractyligenine	[no description available]	low	0	carbotetracyclic compound; dihydroxy monocarboxylic acid; ent-kaurane diterpenoid; tetracyclic diterpenoid	plant metabolite
dihydrogenistin	[no description available]	low	0	beta-D-glucoside; hydroxyisoflavanone; monosaccharide derivative	plant metabolite
n-benzylhexadecanamide	[no description available]	low	0	macamide; secondary carboxamide	EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; neuroprotective agent; plant metabolite
triphosphate	[no description available]	low	0	aldehyde; indole alkaloid; organic heteropentacyclic compound	plant metabolite
aspalathin	[no description available]	low	0	C-glycosyl compound; catechols; dihydrochalcones; polyketide; polyphenol	antioxidant; EC 1.17.3.2 (xanthine oxidase) inhibitor; hypoglycemic agent; plant metabolite
glyceryl ferulate	[no description available]	low	0	1-monoglyceride; aromatic ether; enoate ester; phenols	antioxidant; plant metabolite; ultraviolet filter
obolactone	[no description available]	low	0	2-pyranones; 4-pyranones	antineoplastic agent; plant metabolite
quinine	[no description available]	low	0	Aspidosperma alkaloid; epoxide; methyl ester; monoterpenoid indole alkaloid; organic heterohexacyclic compound	plant metabolite
alpha-onocerin	[no description available]	low	0	diol; olefinic compound; secondary alcohol; triterpenoid	plant metabolite
kalopanax saponin b	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
ginsenoside rd	[no description available]	low	0	beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	anti-inflammatory drug; apoptosis inducer; immunosuppressive agent; neuroprotective agent; plant metabolite; vulnerary
(+)-dehydrodiconiferyl alcohol	[no description available]	low	0	dehydrodiconiferyl alcohol	antioxidant; plant metabolite
viridiflorol	[no description available]	low	0	carbotricyclic compound; sesquiterpenoid; tertiary alcohol	anti-inflammatory agent; antifeedant; antimycobacterial drug; plant metabolite; volatile oil component
gedunin	[no description available]	low	0	acetate ester; enone; epoxide; furans; lactone; limonoid; organic heteropentacyclic compound; pentacyclic triterpenoid	antimalarial; antineoplastic agent; Hsp90 inhibitor; plant metabolite
morelloflavone	[no description available]	low	0	biflavonoid; hydroxyflavanone; hydroxyflavone	plant metabolite
2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
azadiradione	[no description available]	low	0	acetate ester; cyclic terpene ketone; furans; limonoid; tetracyclic triterpenoid	anti-inflammatory agent; antimycobacterial drug; plant metabolite
oplodiol	[no description available]	low	0	carbobicyclic compound; octahydronaphthalenes; secondary alcohol; sesquiterpenoid; tertiary alcohol	plant metabolite
roburic acid	[no description available]	low	0	monocarboxylic acid; olefinic compound; tetracyclic triterpenoid	plant metabolite
ginsenoside rc	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	hypoglycemic agent; plant metabolite
ginsenoside rh1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	plant metabolite
ginsenoside rb3	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antidepressant; antioxidant; cardioprotective agent; neuroprotective agent; NMDA receptor antagonist; plant metabolite
eriodictyol 7-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; flavanone glycoside; monosaccharide derivative; trihydroxyflavanone	plant metabolite; radical scavenger
5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one	[no description available]	low	0	alkaloid; chromones; hydroxypiperidine; resorcinols; tertiary amino compound	anti-inflammatory agent; anti-ulcer drug; anticholesteremic drug; antileishmanial agent; antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; fungal metabolite; plant metabolite
astragaloside IV	[no description available]	low	0	pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; antioxidant; EC 4.2.1.1 (carbonic anhydrase) inhibitor; neuroprotective agent; plant metabolite; pro-angiogenic agent
1-O-feruloyl-beta-D-glucose	[no description available]	low	0	aromatic ether; beta-D-glucoside; cinnamate ester; phenols	antioxidant; plant metabolite
astragaloside ii	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; oxolanes; pentacyclic triterpenoid; triterpenoid saponin	plant metabolite
ligstroside	[no description available]	low	0	beta-D-glucoside; diester; methyl ester; phenols; pyrans; secoiridoid glycoside	antineoplastic agent; plant metabolite
23-hydroxyursolic acid	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
dihydroconiferyl alcohol glucoside	[no description available]	low	0	beta-D-glucoside; monomethoxybenzene; monosaccharide derivative; primary alcohol	plant metabolite
oroxylin a-7-o-glucuronide	[no description available]	low	0	beta-D-glucosiduronic acid; glycosyloxyflavone; monohydroxyflavone; monomethoxyflavone; monosaccharide derivative	plant metabolite
5-deoxystrigol	[no description available]	low	0	indenofuran; strigolactone	plant metabolite
2,3-dihydrowithaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; secondary alcohol; withanolide	plant metabolite
vibsanin b	[no description available]	low	0	cyclic terpene ketone; enone; tertiary alcohol; vibsane diterpenoid	plant growth retardant; plant metabolite
malonylgenistin	[no description available]	low	0	beta-D-glucoside; glycosyloxyisoflavone; hydroxyisoflavone; malonate ester; monosaccharide derivative	plant metabolite
adonixanthin	[no description available]	low	0	carotenone; cyclic ketone; secondary alcohol	algal metabolite; animal metabolite; antineoplastic agent; bacterial metabolite; marine metabolite; plant metabolite
niga-ichigoside f1	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; pentacyclic triterpenoid; tetrol; triterpenoid saponin	plant metabolite
cinnamtannin a2	[no description available]	low	0	proanthocyanidin	plant metabolite
miltiradiene	[no description available]	low	0	abietadiene; carbotricyclic compound	plant metabolite
tricin 4'-o-(threo-beta-guaiacylglyceryl) ether	[no description available]	low	0	dimethoxybenzene; flavonolignan; polyphenol; primary alcohol; secondary alcohol	plant metabolite
triptotriterpenic acid a	[no description available]	low	0	diol; hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
cycloeucalenone	[no description available]	low	0	3-oxo-5alpha-steroid; cyclic terpene ketone; pentacyclic triterpenoid	plant metabolite
deoxyaconitine	[no description available]	low	0	acetate ester; benzoate ester; bridged compound; diol; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary amino compound	plant metabolite
ginsenoside rg2	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	anticoagulant; cardioprotective agent; plant metabolite
cauloside D	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one	[no description available]	low	0	aromatic ether; homoisoflavonoid; polyphenol	angiogenesis modulating agent; plant metabolite
vindolinine	[no description available]	low	0	methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	plant metabolite
rubusoside	[no description available]	low	0	beta-D-glucoside; bridged compound; steviol glycoside; tetracyclic diterpenoid	plant metabolite; sweetening agent
madecassoside	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; trisaccharide derivative; triterpenoid saponin	anti-inflammatory agent; antioxidant; antirheumatic drug; plant metabolite; vulnerary
6-tuliposide b	[no description available]	low	0	6-O-acyl-D-glucose; enoate ester	antibacterial agent; antifungal agent; plant metabolite
quercetin 3-o-glucoside-7-o-rhamnoside	[no description available]	low	0	beta-D-glucoside; quercetin O-glucoside; trihydroxyflavone	plant metabolite; trypanocidal drug
10-nonacosanol	[no description available]	low	0	secondary fatty alcohol; ultra-long-chain fatty alcohol	plant metabolite
(E)-sinapaldehyde 4-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; cinnamaldehydes; dimethoxybenzene; monosaccharide derivative	plant metabolite
1-(4-hydroxyphenyl)-7-phenyl-(6E)-hept-6-en-3-one	[no description available]	low	0	diarylheptanoid; ketone; phenols	plant metabolite
kurarinol	[no description available]	low	0	4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone	anti-inflammatory agent; antioxidant; plant metabolite
2,3-dihydro-3beta-O-sulfate withaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; steroid sulfate; withanolide	antineoplastic agent; metabolite; plant metabolite
gypenoside XVII	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	plant metabolite
euonine	[no description available]	low	0	acetate ester; dihydroagarofuran sesquiterpenoid; macrolide; pyridine alkaloid; sesquiterpene alkaloid	immunosuppressive agent; insecticide; plant metabolite
picrinine	[no description available]	low	0	alkaloid ester; indole alkaloid; methyl ester; organic heteropentacyclic compound; polycyclic ether	analgesic; anti-asthmatic agent; anti-inflammatory agent; antitussive; plant metabolite
(20R)-ginsenoside Rg3	[no description available]	low	0	ginsenoside; glycoside; tetracyclic triterpenoid	antioxidant; plant metabolite
epoxyazadiradione	[no description available]	low	0	acetate ester; cyclic terpene ketone; epoxide; furans; limonoid; pentacyclic triterpenoid	anti-inflammatory agent; insecticide; plant metabolite
n-(2-(5-methoxy-2-oxo-2,3-dihydro-1h-indol-3-yl)ethyl)acetamide	[no description available]	low	0	acetamides; hydroxyindoles; tryptamines	antineoplastic agent; apoptosis inducer; plant metabolite
ascorbic acid	[no description available]	low	0	ascorbic acid; vitamin C	coenzyme; cofactor; flour treatment agent; food antioxidant; food colour retention agent; geroprotector; plant metabolite; skin lightening agent
salicylates	[no description available]	low	0	monohydroxybenzoate	plant metabolite
orobanchol	[no description available]	low	0	indenofuran; secondary alcohol; strigolactone	plant metabolite
oleuropein aglycone	[no description available]	low	0	catechols; diester; lactol; methyl ester; pyrans; secoiridoid	anti-inflammatory agent; antioxidant; mTOR inhibitor; neuroprotective agent; plant metabolite; TRPA1 channel agonist
stemmadenine	[no description available]	low	0	Aspidosperma alkaloid; methyl ester; monoterpenoid indole alkaloid; organic heterotetracyclic compound; primary alcohol	plant metabolite
capilliposide b	[no description available]	low	0	alpha-L-arabinopyranoside; bridged compound; cyclic ether; diol; hexacyclic triterpenoid; hexanoate ester; lactol; secondary alcohol; tetrasaccharide derivative; triterpenoid saponin	antineoplastic agent; plant metabolite
paeoniflorigenone	[no description available]	low	0	alicyclic ketone; benzoate ester; bridged compound; cyclic acetal; lactol; monoterpenoid	neuromuscular agent; plant metabolite
maysin	[no description available]	low	0	disaccharide derivative; flavone C-glycoside; secondary alpha-hydroxy ketone; tetrahydroxyflavone	insecticide; neuroprotective agent; plant metabolite
cryptocaryol a	[no description available]	low	0	2-pyranones; pentol	plant metabolite
gypenoside LXXV	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	plant metabolite
chrysopine	[no description available]	low	0	amino acid opine; carboxamide; delta-lactone; secondary amino compound; spiroketal; triol	plant metabolite
ebc-46	[no description available]	low	0	diester; diterpenoid; organic heteropentacyclic compound; phorbol ester	antineoplastic agent; plant metabolite; protein kinase C agonist
wilforgine	[no description available]	low	0	acetate ester; dihydroagarofuran sesquiterpenoid; furans; macrocyclic lactone; organic heteropentacyclic compound; pyridine alkaloid	plant metabolite
dehydrotomatine	[no description available]	low	0	alkaloid antibiotic; glycoside; steroid alkaloid; tetrasaccharide derivative	antifungal agent; phytotoxin; plant metabolite
biliatresone	[no description available]	low	0	aromatic ether; aromatic ketone; benzodioxoles; enone; phenols	plant metabolite; toxin
cyclic gmp	[no description available]	low	0	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
deoxyinosine	[no description available]	low	0	purine 2'-deoxyribonucleoside; purines 2'-deoxy-D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
deoxyguanosine triphosphate	[no description available]	low	0	deoxyguanosine phosphate; guanyl deoxyribonucleotide; purine 2'-deoxyribonucleoside 5'-triphosphate	Arabidopsis thaliana metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
guanosine diphosphate mannose	[no description available]	low	0	GDP-D-mannose	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite

Article	Year
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function. Molecules (Basel, Switzerland), Jun-14, Volume: 27, Issue: 12	2022
Exploring the inhibitory effects of liquiritigenin against tau fibrillation and related neurotoxicity as a model of preventive care in Alzheimer's disease. International journal of biological macromolecules, Jul-31, Volume: 183	2021
Liquiritigenin-Loaded Submicron Emulsion Protects Against Doxorubicin-Induced Cardiotoxicity via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activity. International journal of nanomedicine, Volume: 15	2020
Attenuation of Aβ toxicity by promotion of mitochondrial fusion in neuroblastoma cells by liquiritigenin. Archives of pharmacal research, Volume: 39, Issue: 8	2016
Extracts of Glycyrrhiza uralensis and isoliquiritigenin counteract amyloid-β toxicity in Caenorhabditis elegans. Planta medica, Volume: 81, Issue: 5	2015
Protective effect of liquiritigenin against methylglyoxal cytotoxicity in osteoblastic MC3T3-E1 cells. Food & function, Jul-25, Volume: 5, Issue: 7	2014
Liquiritigenin inhibits Abeta(25-35)-induced neurotoxicity and secretion of Abeta(1-40) in rat hippocampal neurons. Acta pharmacologica Sinica, Volume: 30, Issue: 7	2009
Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Volume: 45, Issue: 1	2007
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Liquiritigenin-Loaded Submicron Emulsion Protects Against Doxorubicin-Induced Cardiotoxicity via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activity. International journal of nanomedicine, Volume: 15	2020
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology, Volume: 96, Issue: 5	2019
Influence of Jiegeng on Pharmacokinetic Properties of Flavonoids and Saponins in Gancao. Molecules (Basel, Switzerland), Sep-21, Volume: 22, Issue: 10	2017
In vivo gastroprotective effect along with pharmacokinetics, tissue distribution and metabolism of isoliquiritigenin in mice. Planta medica, Volume: 81, Issue: 7	2015
Pharmacokinetics of isoliquiritigenin and its metabolites in rats: low bioavailability is primarily due to the hepatic and intestinal metabolism. Planta medica, Volume: 79, Issue: 17	2013
Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect. Xenobiotica; the fate of foreign compounds in biological systems, Volume: 39, Issue: 6	2009
Aromatase inhibition by bioavailable methylated flavones. The Journal of steroid biochemistry and molecular biology, Volume: 107, Issue: 1-2	2007
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

liquiritigenin

Description

Cross-References

Synonyms (57)

Research Excerpts

Overview

Effects

Treatment

Roles (2)

Drug Classes (1)

Pathways (3)

Protein Targets (15)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (117)

Molecular Functions (60)

Ceullar Components (41)

Bioassays (131)

Research

Studies (207)

Study Types

Research Highlights

Safety/Toxicity (8)

Pharmacokinetics (15)

Bioavailability (7)

Dosage (2)

Interactions (1)

Condition	Relationship Strength	Studies
Academic Disorder, Developmental	low	1
Acute Confusional Senile Dementia	low	4
Acute Disease	low	1
Acute Kidney Failure	low	2
Acute Kidney Injury	low	2
Acute Kidney Insufficiency	low	2
Acute Liver Injury, Drug-Induced	low	5
Acute Lung Injury	low	1
Acute Renal Failure	low	2
Acute Renal Injury	low	2
Acute Renal Insufficiency	low	2
Adenocarcinoma	low	1
Adenocarcinoma, Basal Cell	low	1
Adenocarcinoma, Granular Cell	low	1
Adenocarcinoma, Oxyphilic	low	1
Adenocarcinoma, Tubular	low	1
Adenoma, Malignant	low	1
Adjuvant Arthritis	low	2
Adult Learning Disabilities	low	1
Adult Learning Disorders	low	1
Age-Related Memory Disorders	low	3
Age-Related Osteoporosis	low	2
Allodynia	low	2
Allodynia, Mechanical	low	2
Allodynia, Tactile	low	2
Allodynia, Thermal	low	2
Alloxan Diabetes	low	2
Alzheimer Dementia	low	4
Alzheimer Disease	low	4
Alzheimer Disease, Early Onset	low	4
Alzheimer Disease, Late Onset	low	4
Alzheimer Sclerosis	low	4
Alzheimer Syndrome	low	4
Alzheimer Type Senile Dementia	low	4
Alzheimer-Type Dementia (ATD)	low	4
Alzheimer's Disease	low	4
Alzheimer's Disease, Focal Onset	low	4
Alzheimer's Diseases	low	4
Anasarca	low	1
Angiogenesis, Pathologic	low	2
Angiogenesis, Pathological	low	2
Arthritis, Adjuvant	low	2
Arthritis, Adjuvant-Induced	low	2
Arthritis, Collagen-Induced	low	2
Arthritis, Experimental	low	2
Arthritis, Rheumatoid	low	1
Asthma	low	1
Asthma, Bronchial	low	1
Astrocytosis	low	1
Astrogliosis	low	1
Atrophy, Muscle	low	1
B16 Melanoma	low	1
Benign Neoplasms	low	5
Benign Neoplasms, Brain	low	1
Bilirubinemia	low	1
Body Weight	low	4
Bone Cancer	low	1
Bone Loss, Age-Related	low	2
Bone Loss, Osteoclastic	low	2
Bone Neoplasms	low	1
Bone Resorption	low	2
Brain Cancer	low	1
Brain Inflammation	low	1
Brain Metastases	low	1
Brain Neoplasm, Primary	low	1
Brain Neoplasms	low	1
Brain Neoplasms, Benign	low	1
Brain Neoplasms, Malignant	low	1
Brain Neoplasms, Malignant, Primary	low	1
Brain Neoplasms, Primary Malignant	low	1
Brain Tumor, Primary	low	1
Brain Tumor, Recurrent	low	1
Brain Tumors	low	1
Breast Cancer	low	7
Breast Carcinoma	low	7
Breast Neoplasms	low	7
Breast Tumors	low	7
Bright Disease	low	1
Bronchial Asthma	low	1
Cancer	low	5
Cancer of Bone	low	1
Cancer of Brain	low	1
Cancer of Breast	low	7
Cancer of Liver	low	3
Cancer of Lung	low	2
Cancer of Ovary	low	1
Cancer of Pancreas	low	2
Cancer of Pituitary	low	1
Cancer of the Bone	low	1
Cancer of the Brain	low	1
Cancer of the Breast	low	7
Cancer of the Liver	low	3
Cancer of the Lung	low	2
Cancer of the Ovary	low	1
Cancer of the Pancreas	low	2
Cancer of the Pituitary	low	1
Cancer, Hepatocellular	low	3
Candida Infection	low	1
Candidiasis	low	1
Capillary Leak Syndrome	low	1
Carcinogenesis	low	1
Carcinoma, Cribriform	low	1
Carcinoma, Granular Cell	low	1
Carcinoma, Hepatocellular	low	4
Carcinoma, Small Cell Lung	low	1
Carcinoma, Tubular	low	1
Cardiac Diseases	low	2
Cardiac Disorders	low	2
Cardiac Failure	low	1
Cardiac Rupture, Traumatic	low	1
Cardiac Toxicity	low	1
Cardiotoxicity	low	1
Chemical and Drug Induced Liver Injury	low	5
Chemically-Induced Liver Toxicity	low	5
Chronic Disease	low	1
Chronic Illness	low	1
Chronic Kidney Diseases	low	1
Chronic Kidney Insufficiency	low	1
Chronic Lung Injury	low	1
Chronic Renal Diseases	low	1
Chronic Renal Insufficiency	low	1
Chronically Ill	low	1
Cirrhosis	low	2
Cirrhosis, Liver	low	2
Clarkson Disease	low	1
Clinical Capillary Leak Syndrome	low	1
Cognitive Decline	low	2
Cognitive Dysfunction	low	2
Cognitive Impairments	low	2
Colitis	low	1
Collagen Arthritis	low	2
Colorectal Cancer	low	1
Colorectal Carcinoma	low	1
Colorectal Neoplasms	low	1
Colorectal Tumors	low	1
Complications of Diabetes Mellitus	low	1
Congenital Zika Syndrome	low	1
Congenital Zika Virus Infection	low	1
Congestive Heart Failure	low	1
Cough	low	1
Cramp	low	1
Dementia, Alzheimer Type	low	4
Dementia, Presenile	low	4
Dementia, Primary Senile Degenerative	low	4
Dementia, Senile	low	4
Depression	low	2
Depression, Endogenous	low	1
Depression, Neurotic	low	1
Depression, Unipolar	low	1
Depressive Disorder	low	1
Depressive Syndrome	low	1
Dermatitis	low	1
Developmental Academic Disability	low	1
Developmental Academic Disorder	low	1
Developmental Disabilities of Scholastic Skills	low	1
Developmental Disorders of Scholastic Skills	low	1
Diabetes Complications	low	1
Diabetes Mellitus	low	1
Diabetes Mellitus, Experimental	low	2
Diabetes-Related Complications	low	1
Diabetic Complications	low	1
Diabetic Glomerulosclerosis	low	1
Diabetic Kidney Disease	low	1
Diabetic Nephropathies	low	1
Diabetic Nephropathy	low	1
Disease Models, Animal	low	18
Dropsy	low	1
Drug-Induced Acute Liver Injury	low	5
Drug-Induced Liver Disease	low	5
Drug-Induced Liver Injury	low	5
Dyspepsia	low	1
Early Onset Alzheimer Disease	low	4
Edema	low	1
Encephalitis	low	1
Encephalitis, Rasmussen	low	1
ER-Negative PR-Negative HER2-Negative Breast Cancer	low	2
ER-Negative PR-Negative HER2-Negative Breast Neoplasms	low	2
Experimental Diabetes Mellitus	low	2
Experimental Melanoma	low	1
Experimental Melanomas	low	1
Extravascular Hemolysis	low	1
Familial Alzheimer Disease (FAD)	low	4
Fatty Liver	low	1
Fatty Liver, Nonalcoholic	low	2
Fever, Zika	low	1
Fibrosis	low	2
Fibrosis, Liver	low	2
Focal Onset Alzheimer's Disease	low	4
Gastric Ulcer	low	1
Glial Cell Tumors	low	4
Glial Scar	low	1
Glioma	low	4
Gliosis	low	1
Glomerulonephritis	low	1
Glomerulosclerosis, Diabetic	low	1
Grippe	low	1
Haemolysis	low	1
Harding Passey Melanoma	low	1
Heart Decompensation	low	1
Heart Disease, Ischemic	low	1
Heart Diseases	low	2
Heart Disorders	low	2
Heart Failure	low	1
Heart Failure, Congestive	low	1
Heart Failure, Left-Sided	low	1
Heart Failure, Right-Sided	low	1
Heart Injuries	low	1
Heart Rupture, Traumatic	low	1
Hemolysis	low	1
Hepatic Cancer	low	3
Hepatic Cirrhosis	low	2
Hepatic Neoplasms	low	3
Hepatic Veno Occlusive Disease	low	2
Hepatic Veno-Occlusive Disease	low	2
Hepatitis, Animal	low	1
Hepatitis, Drug-Induced	low	5
Hepatitis, Toxic	low	5
Hepatocellular Cancer	low	3
Hepatocellular Carcinoma	low	4
Hepatoma	low	4
Human Flu	low	1
Human Influenza	low	1
Human Mammary Carcinoma	low	7
Hydrops	low	1
Hyperalgesia	low	2
Hyperalgesia, Mechanical	low	2
Hyperalgesia, Primary	low	2
Hyperalgesia, Secondary	low	2
Hyperalgesia, Tactile	low	2
Hyperalgesia, Thermal	low	2
Hyperalgesic Sensations	low	2
Hyperalgia	low	2
Hyperalgia, Mechanical	low	2
Hyperalgia, Primary	low	2
Hyperalgia, Secondary	low	2
Hyperbilirubinemia	low	1
Hyperglycemia	low	1
Hyperglycemia, Postprandial	low	1
Hyperlipemia	low	1
Hyperlipidemia	low	1
Hyperlipidemias	low	1
Hyperuricemia	low	1
Indigestion	low	1
Infections, Plasmodium	low	1
Inflammation	low	6
Inflammation, Brain	low	1
Influenza	low	1
Influenza in Humans	low	1
Influenza, Human	low	1
Injuries, Heart	low	1
Innate Inflammatory Response	low	6
Insulin Resistance	low	2
Insulin Sensitivity	low	2
Intracapillary Glomerulosclerosis	low	1
Intracranial Neoplasms	low	1
Intravascular Hemolysis	low	1
Invasiveness, Neoplasm	low	4
Ischemia, Myocardial	low	1
Ischemic Heart Disease	low	1
Kidney Failure, Acute	low	2
Kidney Insufficiency, Acute	low	2
Kidney Insufficiency, Chronic	low	1
Kidney Scarring	low	1
Kimmelstiel-Wilson Disease	low	1
Kimmelstiel-Wilson Syndrome	low	1
Late Onset Alzheimer Disease	low	4
Learning Disabilities	low	1
Learning Disorders	low	1
Learning Disorders, Adult	low	1
Learning Disturbance	low	1
Left-Sided Heart Failure	low	1
Limb Cramp	low	1
Lipemia	low	1
Lipidemia	low	1
Liver Cancer	low	3
Liver Cancer, Adult	low	4
Liver Cell Carcinoma	low	4
Liver Cell Carcinoma, Adult	low	4
Liver Cirrhosis	low	2
Liver Diseases	low	1
Liver Dysfunction	low	1
Liver Fibrosis	low	2
Liver Injury, Drug-Induced	low	5
Liver Injury, Drug-Induced, Acute	low	5
Liver Neoplasms	low	3
Liver Steatosis	low	1
Lung Cancer	low	2
Lung Injuries	low	1
Lung Injury	low	1
Lung Injury, Acute	low	1
Lung Neoplasms	low	2
Malaria	low	1
Malignancy	low	5
Malignant Glioma	low	4
Malignant Neoplasm of Breast	low	7
Malignant Neoplasms	low	5
Malignant Neoplasms, Brain	low	1
Malignant Primary Brain Neoplasms	low	1
Malignant Primary Brain Tumors	low	1
Malignant Tumor of Breast	low	7
Malnourishment	low	1
Malnutrition	low	1
Mammary Cancer	low	7
Mammary Carcinoma, Human	low	7
Mammary Neoplasm, Human	low	7
Mammary Neoplasms, Human	low	7
Marsh Fever	low	1
Mechanical Allodynia	low	2
Mechanical Hyperalgesia	low	2
Melancholia	low	1
Melanoma, B16	low	1
Melanoma, Cloudman S91	low	1
Melanoma, Experimental	low	1
Melanoma, Harding-Passey	low	1
Melanomas, Experimental	low	1
Memory Deficits	low	3
Memory Disorder, Semantic	low	3
Memory Disorder, Spatial	low	3
Memory Disorders	low	3
Memory Disorders, Age-Related	low	3
Memory Loss	low	3
Menopause	low	1
Mental Deterioration	low	2
Mild Cognitive Impairment	low	2
Mild Neurocognitive Disorder	low	2
Mixed Glioma	low	4
Moniliasis	low	1
Muscle Contraction	low	1
Muscle Cramp	low	1
Muscular Atrophy	low	1
Muscular Cramp	low	1
Myocardial Failure	low	1
Myocardial Ischemia	low	1
NAFLD	low	2
Necrosis	low	1
Neoplasia	low	5
Neoplasm	low	5
Neoplasm Invasion	low	4
Neoplasm Invasiveness	low	4
Neoplasms	low	5
Neoplasms, Benign	low	5
Neoplasms, Bone	low	1
Neoplasms, Brain	low	1
Neoplasms, Brain, Benign	low	1
Neoplasms, Brain, Malignant	low	1
Neoplasms, Brain, Primary	low	1
Neoplasms, Breast	low	7
Neoplasms, Colorectal	low	1
Neoplasms, Hepatic	low	3
Neoplasms, Intracranial	low	1
Neoplasms, Liver	low	3
Neoplasms, Lung	low	2
Neoplasms, Ovarian	low	1
Neoplasms, Pancreatic	low	2
Neoplasms, Pulmonary	low	2
Neovascularization, Pathologic	low	2
Neovascularization, Pathological	low	2
Nerve Pain	low	1
Neuralgia	low	1
Neuralgia, Atypical	low	1
Neuralgia, Iliohypogastric Nerve	low	1
Neuralgia, Ilioinguinal	low	1
Neuralgia, Perineal	low	1
Neuralgia, Stump	low	1
Neuralgia, Supraorbital	low	1
Neuralgia, Vidian	low	1
Neuroblastoma	low	1
Neurodynia	low	1
Neurogenic Muscular Atrophy	low	1
Neuropathic Pain	low	1
Neurosis, Depressive	low	1
Neurotrophic Muscular Atrophy	low	1
Nodular Glomerulosclerosis	low	1
Non-alcoholic Fatty Liver Disease	low	2
Nonalcoholic Fatty Liver Disease	low	2
Nonalcoholic Steatohepatitis	low	2
Nutritional Deficiency	low	1
Oat Cell Carcinoma of Lung	low	1
Oat Cell Lung Cancer	low	1
Oncogenesis	low	1
Osteoclastic Bone Loss	low	2
Osteogenic Sarcoma	low	1
Osteoporosis	low	2
Osteoporosis, Age-Related	low	2
Osteoporosis, Involutional	low	2
Osteoporosis, Post-Traumatic	low	2
Osteoporosis, Senile	low	2
Osteosarcoma	low	1
Osteosarcoma Tumor	low	1
Ovarian Cancer	low	1
Ovarian Neoplasms	low	1
Ovary Cancer	low	1
Ovary Neoplasms	low	1
Paludism	low	1
Pancreas Cancer	low	2
Pancreas Neoplasms	low	2
Pancreatic Cancer	low	2
Pancreatic Neoplasms	low	2
Paroxysmal Nerve Pain	low	1
Pathologic Angiogenesis	low	2
Pathologic Neovascularization	low	2
Pituitary Adenoma	low	1
Pituitary Cancer	low	1
Pituitary Carcinoma	low	1
Pituitary Neoplasms	low	1
Pituitary Tumors	low	1
Plasmodium Infections	low	1
Polycystic Ovarian Syndrome	low	1
Polycystic Ovary Syndrome	low	1
Polycystic Ovary Syndrome 1	low	1
Postprandial Hyperglycemia	low	1
Pregnancy	low	1
Presenile Alzheimer Dementia	low	4
Primary Brain Neoplasms	low	1
Primary Malignant Brain Neoplasms	low	1
Primary Malignant Brain Tumors	low	1
Primary Senile Degenerative Dementia	low	4
Pulmonary Cancer	low	2
Pulmonary Injury	low	1
Pulmonary Neoplasms	low	2
Rasmussen Encephalitis	low	1
Rasmussen Syndrome	low	1
Rasmussen's Syndrome	low	1
Remittent Fever	low	1
Renal Failure, Acute	low	2
Renal Insufficiency, Acute	low	2
Renal Insufficiency, Chronic	low	1
Retention Disorders, Cognitive	low	3
Rheumatoid Arthritis	low	1
Right-Sided Heart Failure	low	1
Sarcoma, Osteogenic	low	1
Scholastic Skills Development Disorders	low	1
Sclerocystic Ovarian Degeneration	low	1
Sclerocystic Ovaries	low	1
Sclerocystic Ovary Syndrome	low	1
Semantic Memory Disorder	low	3
Senile Dementia, Acute Confusional	low	4
Senile Dementia, Alzheimer Type	low	4
Senile Osteoporosis	low	2
Sensitivity and Specificity	low	3
Sinusoidal Obstruction Syndrome	low	2
Skin Aging	low	1
Small Cell Cancer Of The Lung	low	1
Small Cell Lung Cancer	low	1
Small Cell Lung Carcinoma	low	1
Spatial Memory Disorder	low	3
Steatohepatitis	low	1
Steatosis of Liver	low	1
Stein-Leventhal Syndrome	low	1
Stomach Ulcer	low	1
Streptozocin Diabetes	low	2
Streptozotocin Diabetes	low	2
Systemic Capillary Leak Syndrome	low	1
Tactile Allodynia	low	2
Thermal Allodynia	low	2
Toxic Hepatitis	low	5
Triple Negative Breast Cancer	low	2
Triple Negative Breast Neoplasms	low	2
Triple-Negative Breast Cancer	low	2
Triple-Negative Breast Neoplasm	low	2
Tumorigenesis	low	1
Tumors	low	5
Tumors, Breast	low	7
Undernutrition	low	1
Unipolar Depression	low	1
Veno-Occlusive Disease, Hepatic	low	2
Visceral Steatosis	low	1
Weight Gain	low	1
Zika Fever	low	1
Zika Virus Disease	low	1
Zika Virus Infection	low	1
ZikV Infection	low	1

Article	Year
Simultaneous Determination and Pharmacokinetic Characterization of Glycyrrhizin, Isoliquiritigenin, Liquiritigenin, and Liquiritin in Rat Plasma Following Oral Administration of Glycyrrhizae Radix Extract. Molecules (Basel, Switzerland), May-10, Volume: 24, Issue: 9	2019
Influence of Jiegeng on Pharmacokinetic Properties of Flavonoids and Saponins in Gancao. Molecules (Basel, Switzerland), Sep-21, Volume: 22, Issue: 10	2017
An LC-MS/MS method for determination of bioactive components of liquorice and Semen Strychni in rat plasma: Application to a pharmacokinetics study. Drug testing and analysis, Volume: 10, Issue: 2	2018
Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats. Molecules (Basel, Switzerland), Sep-30, Volume: 20, Issue: 10	2015
The influence of compatibility of processed radix Aconiti Kusnezoffii on the pharmacokinetic of four components in Glycyrrhiza uralensis Fisch. Journal of ethnopharmacology, Jul-01, Volume: 169	2015
In vivo gastroprotective effect along with pharmacokinetics, tissue distribution and metabolism of isoliquiritigenin in mice. Planta medica, Volume: 81, Issue: 7	2015
Simultaneous determination of puerarin, daidzin, daidzein, paeoniflorin, albiflorin, liquiritin and liquiritigenin in rat plasma and its application to a pharmacokinetic study of Ge-Gen Decoction by a liquid chromatography-electrospray ionization-tandem m Journal of pharmaceutical and biomedical analysis, Volume: 95	2014
Pharmacokinetics of isoliquiritigenin and its metabolites in rats: low bioavailability is primarily due to the hepatic and intestinal metabolism. Planta medica, Volume: 79, Issue: 17	2013
Chiral analytical method development of liquiritigenin with application to a pharmacokinetic study. Biomedical chromatography : BMC, Volume: 27, Issue: 3	2013
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats. The Journal of pharmacy and pharmacology, Volume: 63, Issue: 1	2011
Pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats with acute hepatitis induced by d-galactosamine/lipopolysaccharide or CCl(4). Xenobiotica; the fate of foreign compounds in biological systems, Volume: 40, Issue: 6	2010
Liquiritigenin pharmacokinetics in a rat model of diabetes mellitus induced by streptozotocin: greater formation of glucuronides in the liver, especially M2, due to increased hepatic uridine 5'-diphosphoglucuronic acid level. Metabolism: clinical and experimental, Volume: 59, Issue: 10	2010
Pharmacokinetic interaction between liquiritigenin (LQ) and DDB: increased glucuronidation of LQ in the liver possibly due to increased hepatic blood flow rate by DDB. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Jan-31, Volume: 39, Issue: 1-3	2010
Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect. Xenobiotica; the fate of foreign compounds in biological systems, Volume: 39, Issue: 6	2009
Pharmacokinetics of liquiritigenin in mice, rats, rabbits, and dogs, and animal scale-up. Journal of pharmaceutical sciences, Volume: 98, Issue: 11	2009
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women's breast tissue. Scientific reports, 05-30, Volume: 13, Issue: 1	2023
Pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats with acute hepatitis induced by d-galactosamine/lipopolysaccharide or CCl(4). Xenobiotica; the fate of foreign compounds in biological systems, Volume: 40, Issue: 6	2010
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Preparative separation of liquiritigenin and glycyrrhetic acid from Glycyrrhiza uralensis Fisch using hydrolytic extraction combined with high-speed countercurrent chromatography. Biomedical chromatography : BMC, Volume: 34, Issue: 4	2020
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

liquiritigenin

Description

Related Flora

Cross-References

Synonyms (57)

Research Excerpts

Overview

Effects

Treatment

Roles (2)

Drug Classes (1)

Pathways (3)

Protein Targets (15)

Potency Measurements

Inhibition Measurements

Activation Measurements

Biological Processes (117)

Molecular Functions (60)

Ceullar Components (41)

Bioassays (131)

Research

Studies (207)

Study Types

Related Drugs (1,323)

Related Conditions (472)

Research Highlights

Safety/Toxicity (8)

Pharmacokinetics (15)

Bioavailability (7)

Dosage (2)

Interactions (1)