| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
quinacrine
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.. quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9. | 2.76 | 3 | 0 | acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound | antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor |
levoplast
Levoplast: mixture of acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-, castor oil, celluloidin, collodion & tannins | 2.15 | 1 | 0 | C-nitro compound | |
hippuric acid
hippuric acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #4591. N-benzoylglycine : An N-acylglycine in which the acyl group is specified as benzoyl. | 2.15 | 1 | 0 | N-acylglycine | human blood serum metabolite;
uremic toxin |
imidazole
imidazole: RN given refers to parent cpd. 1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1. | 7.17 | 1 | 0 | imidazole | |
xanthine
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.. 9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated. | 2.15 | 1 | 0 | xanthine | Saccharomyces cerevisiae metabolite |
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. | 2.06 | 1 | 0 | non-proteinogenic alpha-amino acid | |
atrolactic acid
atrolactic acid: see also 3-isomer; RN given refers to parent cpd without isomeric designation; structure | 2.15 | 1 | 0 | 2-hydroxy monocarboxylic acid | |
1,3-dipropyl-8-cyclopentylxanthine
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group. | 2.46 | 2 | 0 | oxopurine | adenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor |
nsc-267703
[no description available] | 2.06 | 1 | 0 | anthracycline | |
etofylline
etofylline: etophyllin appeared once in PubMed: Wien Med Wochenschr. 1986 May 15;136(9):213-8 as a combination drug with theophylline (spelt without e, theophllin) | 2.15 | 1 | 0 | oxopurine | |
n-acetyltryptophan
N-acetyltryptophan : An N-acetylamino acid that is the N-acetyl derivative of tryptophan. | 2.15 | 1 | 0 | N-acetyl-amino acid;
tryptophan derivative | metabolite |
ethacridine
Ethacridine: A topically applied anti-infective agent. | 2.15 | 1 | 0 | acridines | |
dactinomycin
[no description available] | 2.06 | 1 | 0 | cyclodepsipeptide | |
1-aminoindan-1,5-dicarboxylic acid
1-aminoindan-1,5-dicarboxylic acid: structure given in first source | 2.46 | 2 | 0 | | |
altretamine
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine. | 2.15 | 1 | 0 | triamino-1,3,5-triazine | |
amodiaquine
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.. amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position. | 4.18 | 4 | 0 | aminoquinoline;
organochlorine compound;
phenols;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
drug allergen;
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug |
astemizole
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.. astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position. | 2.46 | 2 | 0 | benzimidazoles;
piperidines | anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist |
berberine
[no description available] | 2.06 | 1 | 0 | alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound | antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker |
2,5-di-tert-butylhydroquinone
2,5-di-tert-butylbenzene-1,4-diol : A member of the class of hydroquinones that is benzene-1,4-diol substituted by tert-butyl groups at position 2 and 5. | 2.15 | 1 | 0 | hydroquinones | |
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | 10.09 | 13 | 0 | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug |
aricine
[no description available] | 2.46 | 2 | 0 | cinchona alkaloid | |
clofilium
clofilium: RN given refers to parent cpd; structure | 2.06 | 1 | 0 | benzenes;
organic amino compound | |
clotrimazole
[no description available] | 2.46 | 2 | 0 | conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes | antiinfective agent;
environmental contaminant;
xenobiotic |
cx546
1-(1,4-benzodioxan-6-ylcarbonyl)piperidine: structure in first source | 2.15 | 1 | 0 | | |
dequalinium
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.. dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group. | 2.06 | 1 | 0 | quinolinium ion | antifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor |
diphenhydramine
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.. diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.. antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. | 2.15 | 1 | 0 | ether;
tertiary amino compound | anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative |
diuron
Diuron: A pre-emergent herbicide.. diuron : A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group. | 2.15 | 1 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene | environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic |
nsc-526417
[no description available] | 2.06 | 1 | 0 | | |
gentian violet
crystal violet cation : An iminium ion that is malachite green cation in which the hydrogen at the para- psition of the monosubstituted phenyl group is replaced by a dimethylamino group. | 2.06 | 1 | 0 | iminium ion | antibacterial agent;
antifungal agent |
glafenine
Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.. glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market. | 2.31 | 1 | 0 | aminoquinoline;
carboxylic ester;
glycol;
organochlorine compound;
secondary amino compound | inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
hexahydrosiladifenidol
[no description available] | 2.06 | 1 | 0 | | |
hydroxychloroquine
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970). hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. | 2.25 | 1 | 0 | aminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug |
ibuprofen
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine | 2.15 | 1 | 0 | monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic |
ipriflavone
ipriflavone : A member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. | 2.15 | 1 | 0 | aromatic ether;
isoflavones | bone density conservation agent |
mebendazole
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.. mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5. | 2.15 | 1 | 0 | aromatic ketone;
benzimidazoles;
carbamate ester | antinematodal drug;
microtubule-destabilising agent;
tubulin modulator |
mefloquine hydrochloride
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol : An organofluorine compound that consists of quinoline bearing trifluoromethyl substituents at positions 2 and 8 as well as a (2-piperidinyl)hydroxymethyl substituent at position 4. | 2.74 | 3 | 0 | organofluorine compound;
piperidines;
quinolines;
secondary alcohol | |
nocodazole
[no description available] | 2.15 | 1 | 0 | aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes | antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator |
moclobemide
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.. moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression. | 2.46 | 2 | 0 | benzamides;
monochlorobenzenes;
morpholines | antidepressant;
environmental contaminant;
xenobiotic |
n-acetyl-4-nitrophenylserinol
N-acetyl-4-nitrophenylserinol: RN given refers to cpd without isomeric designation; structure | 2.46 | 2 | 0 | | |
oxaprozin
Oxaprozin: An oxazole-propionic acid derivative, cyclooxygenase inhibitor, and non-steroidal anti-inflammatory drug that is used in the treatment of pain and inflammation associated with of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; and ARTHRITIS, JUVENILE.. oxaprozin : A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis. | 3.51 | 1 | 0 | 1,3-oxazoles;
monocarboxylic acid | analgesic;
non-steroidal anti-inflammatory drug |
oxiracetam
oxiracetam: structure in first source | 2.46 | 2 | 0 | organonitrogen compound;
organooxygen compound | |
pentamidine
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.. pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. | 2.46 | 2 | 0 | aromatic ether;
carboxamidine;
diether | anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic |
piribedil
Piribedil: A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist. | 2.15 | 1 | 0 | N-arylpiperazine | |
primaquine
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404). primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. | 2.05 | 1 | 0 | aminoquinoline;
aromatic ether;
N-substituted diamine | antimalarial |
procainamide
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.. procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias. | 2.15 | 1 | 0 | benzamides | anti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker |
prometone
prometone: structure. prometon : A methoxy-1,3,5-triazine that is 6-methoxy-1,3,5-triazine-2,4-diamine in which the one of the hydrogens of each amino group is substituted by an isopropyl group. | 2.15 | 1 | 0 | diamino-1,3,5-triazine;
methoxy-1,3,5-triazine | environmental contaminant;
herbicide;
xenobiotic |
pronethalol
pronethalol: was heading 1964-94 (Prov 1964-66); NAPHTHYLISOPROTERENOL was see PRONETHALOL 1977-94; use ETHANOLAMINES to search PRONETHALOL 1966-94 | 2.46 | 2 | 0 | naphthalenes | |
propafenone
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.. propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. | 2.46 | 2 | 0 | aromatic ketone;
secondary alcohol;
secondary amino compound | anti-arrhythmia drug |
propanil
Propanil: A chlorinated anilide that is used as an herbicide.. propanil : An anilide resulting from the formal condensation of the carboxy group of propanoic acid with the amino group of 3,4-dichloroaniline. It is a herbicide used for the treatment of numerous grasses and broad-leaved weeds in rice, potatoes, and wheat. | 2.15 | 1 | 0 | anilide;
dichlorobenzene | herbicide |
pyrimethamine
Maloprim: contains above 2 cpds | 2.46 | 2 | 0 | aminopyrimidine;
monochlorobenzenes | antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor |
scriptaid
scriptide: provokes translocation of GLUT4 to increase glucose uptake; structure in first source | 2.46 | 2 | 0 | isoquinolines | |
sulfadimethoxine
Sulfadimethoxine: A sulfanilamide that is used as an anti-infective agent.. sulfadimethoxine : A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. | 2.15 | 1 | 0 | aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic |
sulfamethazine
Sulfamethazine: A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.. sulfamethazine : A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position. | 2.15 | 1 | 0 | pyrimidines;
sulfonamide antibiotic;
sulfonamide | antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic |
sulfathiazole
Sulfathiazole: A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.. sulfathiazole : A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position. | 2.15 | 1 | 0 | 1,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic |
testosterone
[no description available] | 2.15 | 1 | 0 | 3-hydroxy steroid | androgen |
6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nona(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
[no description available] | 2.46 | 2 | 0 | cyclodepsipeptide | |
2-hydroxybenzylbenzimidazole
2-hydroxybenzylbenzimidazole: RN given refers to cpd without isomeric designation | 2.15 | 1 | 0 | | |
aniline
[no description available] | 2.1 | 1 | 0 | anilines;
primary arylamine | |
etimizol
Etimizol: A xanthine-related, putative nootropic drug. | 2.15 | 1 | 0 | | |
cycloheximide
Cycloheximide: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.. cycloheximide : A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. | 2.46 | 2 | 0 | antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol | anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor |
nifenalol
nifenalol: adrenergic beta-blocker with good antiarrhythmic properties; also tends to lower blood pressure & provide protection against angina; minor descriptor (75-86); on-line & INDEX MEDICUS search ETHANOLAMINES (75-86); RN given refers to parent cpd without isomeric designation | 2.15 | 1 | 0 | C-nitro compound | |
n,n'-diphenyl-4-phenylenediamine
N,N'-diphenyl-4-phenylenediamine: in veterinary medicine, has been used to prevent vitamin E deficiency in lambs; structure. N,N'-diphenyl-1,4-phenylenediamine : An N-substituted diamine that is 1,4-phenylenediamine in which one hydrogen from each amino group is replaced by a phenyl group. | 2.1 | 1 | 0 | N-substituted diamine;
secondary amino compound | antioxidant |
bis(4-hydroxyphenyl)sulfone
bis(4-hydroxyphenyl)sulfone: structure and RN in first source. 4,4'-sulfonyldiphenol : A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. | 2.15 | 1 | 0 | bisphenol;
sulfone | endocrine disruptor;
metabolite |
phanquinone
phanquinone: structure. phanquone : An orthoquinone that is the 5,6-diketo derivative of 4,7-phenanthroline. | 2.46 | 2 | 0 | orthoquinones | |
8-hydroxyquinoline-5-sulfonic acid
8-hydroxyquinoline-5-sulfonic acid: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
4,7-dichloroquinoline
[no description available] | 2.46 | 2 | 0 | | |
salicylanilide
salicylanilide: RN given refers to parent cpd. salicylanilide : An amide of salicylic acid and of aniline; it is therefore both a salicylamide and an anilide. | 2.15 | 1 | 0 | benzanilide fungicide;
salicylamides;
salicylanilides | |
2-phenylbutyric acid
2-phenylbutyric acid : A monocarboxylic acid that is butyric acid substituted by a phenyl group at position 2. | 2.15 | 1 | 0 | benzenes;
monocarboxylic acid | human xenobiotic metabolite |
aminacrine
Aminacrine: A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.. 9-aminoacridine : An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections. | 2.1 | 1 | 0 | aminoacridines;
primary amino compound | acid-base indicator;
antiinfective agent;
antiseptic drug;
fluorescent dye;
MALDI matrix material;
mutagen |
4,4'-dimethoxybenzophenone
4,4'-dimethoxybenzophenone: structure in first source | 2.15 | 1 | 0 | | |
quinoline
[no description available] | 2 | 1 | 0 | azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinolines | |
6-phenyl-1,3,5-triazine-2,4-diamine
6-phenyl-1,3,5-triazine-2,4-diamine: structure in first source | 2.15 | 1 | 0 | | |
quinaldic acid
[no description available] | 2.15 | 1 | 0 | quinolinemonocarboxylic acid | human metabolite;
Saccharomyces cerevisiae metabolite |
N-(2-methoxyphenyl)acetamide
[no description available] | 2.15 | 1 | 0 | acetamides;
methoxybenzenes | |
fast red b
Fast Red B: structure in first source. fast red B : An organosulfonate salt composed from 2-methoxy-4-nitrobenzene-1-diazonium and 5-sulfonaphthalene-1-sulfonate in a 1:1 ratio. Used for demostrating enterochromaffin in carcinoid tumours. | 2.15 | 1 | 0 | | |
methylenebis(chloroaniline)
Methylenebis(chloroaniline): Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms.. 4,4'-methylene-bis-(2-chloroaniline) : A chloroaniline that consists of two 2-chloroaniline units joined by a methylene bridge. | 2.15 | 1 | 0 | chloroaniline | metabolite |
4-aminodiphenylamine
4-aminodiphenylamine: RN given refers to parent cpd. p-aminodiphenylamine : An aromatic amine that is the 4-amino derivative of diphenylamine. | 2.1 | 1 | 0 | aromatic amine;
secondary amino compound | allergen |
diphenan
[no description available] | 2.46 | 2 | 0 | diarylmethane | |
di-(4-aminophenyl)ether
di-(4-aminophenyl)ether: structure | 2.15 | 1 | 0 | aromatic ether | |
diphenylguanidine
diphenylguanidine: vulcanization accelerator; RN given refers to parent cpd. 1,3-diphenylguanidine : Guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry. | 2.15 | 1 | 0 | guanidines | allergen |
4-Anilino-4-oxobutanoic acid
[no description available] | 2.15 | 1 | 0 | anilide | |
2-phenylacetamide
2-phenylacetamide: structure. 2-phenylacetamide : A monocarboxylic acid amide that is acetamide substituted by a phenyl group at position 2. | 2.46 | 2 | 0 | monocarboxylic acid amide | mouse metabolite |
4-phenylenediamine
4-phenylenediamine: agent hair dye responsible for contact dermatitis; RN given refers to parent cpd. 1,4-phenylenediamine : A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus. | 2.1 | 1 | 0 | phenylenediamine | allergen;
dye;
hapten;
reagent |
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. | 2.05 | 1 | 0 | pyrrole;
secondary amine | |
mephobarbital
Mephobarbital: A barbiturate that is metabolized to PHENOBARBITAL. It has been used for similar purposes, especially in EPILEPSY, but there is no evidence mephobarbital offers any advantage over PHENOBARBITAL.. mephobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by ethyl and phenyl groups. | 2.15 | 1 | 0 | barbiturates | anticonvulsant |
etryptamine
etryptamine: RN given refers to cpd without isomeric designation | 2.15 | 1 | 0 | indoles | |
sulfacetamide
[no description available] | 2.15 | 1 | 0 | | |
cinchophen
cinchophen: was heading 1963-94; ACIPHENOCHINOLIUM was see CHINOPHEN 1978-94; use QUINOLINES to search CINCHOPHEN 1966-94 | 2.15 | 1 | 0 | quinolines | |
2-aminobenzothiazole
[no description available] | 2.15 | 1 | 0 | benzothiazoles | |
carzenide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
nitrilotriacetic acid
Nitrilotriacetic Acid: A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.) | 2.15 | 1 | 0 | NTA;
tricarboxylic acid | carcinogenic agent;
nephrotoxic agent |
tetraphenylborate
Tetraphenylborate: An anionic compound that is used as a reagent for determination of potassium, ammonium, rubidium, and cesium ions. It also uncouples oxidative phosphorylation and forms complexes with biological materials, and is used in biological assays. | 2.46 | 2 | 0 | | |
n-(2-cyanoethyl)-2-phenylethylamine
N-(2-cyanoethyl)-2-phenylethylamine: prodrug of 2-phenylethylamine | 2.15 | 1 | 0 | | |
cycloguanil hydrochloride
cycloguanil hydrochloride : The hydrochloride salt of cycloguanil. | 2.46 | 2 | 0 | hydrochloride;
organic molecular entity | |
cycloguanil
cycloguanil: the active metabolite of proguanil; antifolate drug; structure in first source. cycloguanil : A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil. | 2.06 | 1 | 0 | triazines | antifolate;
antiinfective agent;
antimalarial;
antiparasitic agent;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor |
cyclooctane
[no description available] | 2.15 | 1 | 0 | | |
triphenyltetrazolium chloride
2,3,5-triphenyltetrazolium chloride : An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. | 2.15 | 1 | 0 | organic chloride salt | dye;
indicator |
triphenyltetrazolium
triphenyltetrazolium: RN given refers to parent cpd. 2,3,5-triphenyltetrazolium : An organic cation that is tetrazole carrying three phenyl substituents at positions 2, 3 and 5. | 2.06 | 1 | 0 | organic cation | |
2,7-diacetylaminofluorene
2,7-diacetylaminofluorene: has been found to induce leukemia in animals; minor descriptor (75-84); on-line search 2-ACETYLAMINOFLUORENE/AA (75-84); Index Medicus search 2-ACETYLAMINOFLUORENE/AA (80-82), FLUORENES (75-79) | 2.15 | 1 | 0 | | |
berbamine
[no description available] | 2.06 | 1 | 0 | phenylpropanoid | |
emetine
Emetine: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.. emetine : A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. | 2.46 | 2 | 0 | isoquinoline alkaloid;
pyridoisoquinoline | antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor |
3,4-pyridinedicarboxylic acid
3,4-pyridinedicarboxylic acid: structure in first source | 2.15 | 1 | 0 | pyridinedicarboxylic acid | |
dequalinium chloride
dequalinium chloride : An organic chloride salt that is the dichloride salt of dequalinium. | 2.46 | 2 | 0 | organic chloride salt | antifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor |
4-(benzoylamino)-2-hydroxybenzoic acid
4-(benzoylamino)-2-hydroxybenzoic acid: Bepask is calcium salt | 2.15 | 1 | 0 | benzamides | |
tropic acid
tropic acid: acid moiety of ester alkaloids hyoscyamine & scopolamine; RN given refers to parent cpd with unspecified isomeric designation; structure. tropic acid : A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a phenyl group, and one of the methyl hydrogens is substituted by a hydroxy group. | 2.15 | 1 | 0 | 3-hydroxy monocarboxylic acid | human xenobiotic metabolite |
8-hydroxy-7-iodo-5-quinolinesulfonic acid
8-hydroxy-7-iodo-5-quinolinesulfonic acid: used with iodine isotopes in radioisotope scanning; structure | 2.15 | 1 | 0 | hydroxyquinoline | |
gentian violet
Gentian Violet: A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.. crystal violet : An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain. | 2.04 | 1 | 0 | organic chloride salt | anthelminthic drug;
antibacterial agent;
antifungal agent;
antiseptic drug;
histological dye |
1-acetylisatin
1-acetylisatin: structure in first source | 2.15 | 1 | 0 | indoledione | |
8-aminoquinoline
[no description available] | 2 | 1 | 0 | | |
6-aminoquinoline
[no description available] | 2 | 1 | 0 | | |
1,2-Dihydroquinolin-2-imine
[no description available] | 2 | 1 | 0 | aminoquinoline | |
4-cumylphenol
[no description available] | 2.15 | 1 | 0 | diarylmethane | |
5-methylisatin
5-methylisatin: structure in first source | 2.15 | 1 | 0 | | |
5-aminoquinoline
[no description available] | 2 | 1 | 0 | | |
2-hydrazinobenzothiazole
[no description available] | 2.15 | 1 | 0 | | |
Berberine chloride (TN)
[no description available] | 2.46 | 2 | 0 | organic molecular entity | |
1,2,3-trimethoxybenzene
1,2,3-trimethoxybenzene : A methoxybenzene that is benzene substituted by methoxy groups at positions 1, 2 and 3 respectively. | 2.15 | 1 | 0 | methoxybenzenes | plant metabolite |
2-amino-5-chlorobenzophenone
2-amino-5-chlorbenzophenone: structure given in first source | 2.15 | 1 | 0 | | |
9,10-dimethylanthracene
9,10-dimethylanthracene: RN given refers to parent ion | 2.46 | 2 | 0 | | |
diphenamid
diphenamid: do not confuse with anti-inflammatory agent difenpiramide; structure | 2.15 | 1 | 0 | diarylmethane | |
4-(4-nitrobenzyl)pyridine
[no description available] | 2.15 | 1 | 0 | | |
c 137
C 137: RN given refers to parent cpd | 2.46 | 2 | 0 | | |
5-methyl-3-phenylisoxazole-4-carboxylic acid
5-methyl-3-phenylisoxazole-4-carboxylic acid: has anti-tumor, antiviral, hypoglycemic, antifungal and anti-HIV activities; structure in first source | 2.15 | 1 | 0 | | |
2-acetylbenzofuran
2-acetylbenzofuran: structure in first source | 2.15 | 1 | 0 | | |
pyrazon
pyrazon: structure; do not confuse with phenazone which is a synonym to antipyrine. chloridazon : A pyridazinone that is pyridazin-3(2H)-one substituted by an amino group at position 5, a chloro group at position 4 and a phenyl group at position 2. | 2.15 | 1 | 0 | benzenes;
organochlorine compound;
primary amino compound;
pyridazinone | environmental contaminant;
herbicide;
xenobiotic |
2-amino-5-nitrobenzophenone
2-amino-5-nitrobenzophenone: urinary metabolite of nitrazepam | 2.15 | 1 | 0 | | |
(4-tert-Butyl-phenoxy)-acetic acid
[no description available] | 2.15 | 1 | 0 | monocarboxylic acid | |
lenacil
lenacil: Russian drug. herbicide : A substance used to destroy plant pests.. lenacil : A cyclopentapyrimidine that is 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione substituted by a cyclohexyl group at position 3. | 2.15 | 1 | 0 | cyclopentapyrimidine | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
chlordesmethyldiazepam
[no description available] | 2.15 | 1 | 0 | benzodiazepine | |
2-amino-2',5-dichlorobenzophenone
2-amino-2',5-dichlorobenzophenone: structure given in first source | 2.15 | 1 | 0 | | |
2-(2'-hydroxyphenyl)benzimidazole
2-(2'-hydroxyphenyl)benzimidazole: structure in first source | 2.15 | 1 | 0 | | |
4-phthalimidobutyric acid
4-phthalimidobutyric acid: teratogen; RN given refers to parent cpd | 2.15 | 1 | 0 | | |
azabutyrone
azabutyrone: Russian drug; RN given refers to parent cpd; structure | 2.15 | 1 | 0 | | |
2-(2-hydroxyphenyl)benzothiazole
2-(1,3-benzothiazol-2-yl)phenol : A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a 2-hydroxyphenyl group at position 2. | 2.15 | 1 | 0 | benzothiazoles;
phenols | geroprotector |
4,5-dichlorocatechol
[no description available] | 2.15 | 1 | 0 | | |
palmatine
burasaine: structure in first source | 2.06 | 1 | 0 | berberine alkaloid;
organic heterotetracyclic compound | plant metabolite |
9-amino-6-chloro-2-methoxyacridine
[no description available] | 2.1 | 1 | 0 | | |
n-butylbenzenesulfonamide
N-butylbenzenesulfonamide: a neurotoxic plasticising agent. N-butylbenzenesulfonamide : A sulfonamide that is benzenesulfonamide substituted by a butyl group at the nitrogen atom. It has been isolated from the plant Prunus africana and has been shown to exhibit antiandrogenic activity. | 2.15 | 1 | 0 | sulfonamide | neurotoxin;
plant metabolite |
3-phenoxybenzoic acid
3-phenoxybenzoic acid: metabolite associated with exposure to pyrethroid insecticides. 3-phenoxybenzoic acid : A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides. | 2.15 | 1 | 0 | phenoxybenzoic acid | human xenobiotic metabolite;
marine xenobiotic metabolite |
4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine
4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine: structure in first source | 2.06 | 1 | 0 | | |
2-(2-hydroxyethylmercapto)benzothiazole
2-(2-hydroxyethylmercapto)benzothiazole: reaction product of 2-mercaptobenzothiazole, well-known rubber vulcanization accelerator; structure in first source | 2.15 | 1 | 0 | | |
carboxin
Carboxin: A systemic agricultural fungicide and seed treatment agent.. carboxin : An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment. | 2.15 | 1 | 0 | anilide fungicide;
anilide;
enamide;
organosulfur heterocyclic compound;
oxacycle;
secondary carboxamide | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
buquinolate
[no description available] | 2.46 | 2 | 0 | | |
meturin
[no description available] | 2.15 | 1 | 0 | | |
2-bromo-N-phenylbenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
4-chlorohippuric acid
4-chlorohippuric acid: metabolite of zomepirac; RN given refers to parent cpd | 2.15 | 1 | 0 | | |
4-chlorophenoxyacetic acid
4-chlorophenoxyacetic acid: RN given refers to parent cpd; structure. (4-chlorophenoxy)acetic acid : A chlorophenoxyacetic acid that is phenoxyacetic acid carrying a chloro substituent at position 4. | 2.15 | 1 | 0 | chlorophenoxyacetic acid;
monochlorobenzenes | phenoxy herbicide |
2,5-dichloro-1,4-phenylenediamine
2,5-dichloro-1,4-phenylenediamine: structure in first source | 2.15 | 1 | 0 | | |
metribuzin
metribuzin : A member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3. | 2.15 | 1 | 0 | 1,2,4-triazines;
cyclic ketone;
organic sulfide | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
2,5-dimethyl-3-furancarboxanilide
2,5-dimethyl-3-furancarboxanilide: structure | 2.15 | 1 | 0 | | |
moricizine hydrochloride
moricizine hydrochloride : A hydrochloride salt obtained from equimola amounts of moricizine and hydrogen chloride. | 2.15 | 1 | 0 | hydrochloride | anti-arrhythmia drug |
2-benzimidazolylguanidine
2-benzimidazolylguanidine: effects chloride efflux in tissue; RN given refers to parent cpd | 2.15 | 1 | 0 | aminoimidazole | |
diflubenzuron
Diflubenzuron: An insect growth regulator which interferes with the formation of the insect cuticle. It is effective in the control of mosquitoes and flies.. diflubenzuron : A benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group. | 2.15 | 1 | 0 | benzoylurea insecticide;
monochlorobenzenes | insect sterilant |
propranolol glycol
propranolol glycol: propranolol metabolite; potent anticonvulsant against strychnine induced convulsions | 2.46 | 2 | 0 | | |
pentafluorobenzoyl-n-phenylethylamine
[no description available] | 2.15 | 1 | 0 | | |
thidiazuron
[no description available] | 2.15 | 1 | 0 | ureas | |
phenthiazamine
phenthiazamine: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
naphthoxybutanolcyclohexylamine
naphthoxybutanolcyclohexylamine: structure | 2.06 | 1 | 0 | | |
staurosporine
[no description available] | 2.06 | 1 | 0 | indolocarbazole alkaloid;
organic heterooctacyclic compound | apoptosis inducer;
bacterial metabolite;
EC 2.7.11.13 (protein kinase C) inhibitor;
geroprotector |
5,5-diphenylbarbituric acid
5,5-diphenylbarbituric acid: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
3-acetamidobenzoic acid
N-acetyl-m-aminobenzoic acid: from Solanum laciniatum; structure in first source | 2.15 | 1 | 0 | | |
dazoxiben hydrochloride
[no description available] | 2.15 | 1 | 0 | | |
simvastatin
Simvastatin: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.. simvastatin : A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug. | 3.51 | 1 | 0 | delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic) | EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug |
succinylsulfanilamide
[no description available] | 2.15 | 1 | 0 | | |
benzylaminopurine
benzylaminopurine: a plant growth regulator. N-benzyladenine : A member of the class of 6-aminopurines that is adenine in which one of the hydrogens of the amino group is replaced by a benzyl group. | 2.15 | 1 | 0 | 6-aminopurines | cytokinin;
plant metabolite |
ciprofloxacin hydrochloride anhydrous
[no description available] | 2.15 | 1 | 0 | hydrochloride | antibacterial drug;
antiinfective agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor |
src-820 r
[no description available] | 2.15 | 1 | 0 | | |
propamidine
propamidine: structure given in first source. propamidine : A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. | 2.06 | 1 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
n(4)-acetylsulfadiazine
N(4)-acetylsulfadiazine: main metabolite of sulfadiazine. N(4)-acetylsulfadiazine : A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a pyrimidin-2-yl group at the nitrogen atom. It is a metabolite of the drug sulfadiazine. | 2.15 | 1 | 0 | acetamides;
pyrimidines;
sulfonamide | marine xenobiotic metabolite |
thionine
thionine: do not confuse with the thionins which is a class of polypeptides; RN above is for the chloride;. thionine : An organic chloride salt composed of 3,7-diaminophenothiazin-5-ium and chloride ions in a 1:1 ratio. A strongly metachromatic dye, useful for the staining of acid mucopolysaccharides. It is also a common nuclear stain and can be used for the demonstration of Nissl substance in nerve cells of the CNS. | 2.04 | 1 | 0 | | |
4-nitro-alpha-acetylamino-beta-hydroxypropiophenone
4-nitro-alpha-acetylamino-beta-hydroxypropiophenone: inhibitory agent for the differentiation of mammalian tuberculosis strains from other Mycobacteria | 2.15 | 1 | 0 | | |
neocuproine
neocuproine: Spectrophotometric determination of copper and ultramicro blood sugar determinations; structure; RN given refers to parent cpd. neocuproine : A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two methyl substituents at positions 2 and 9. | 2.46 | 2 | 0 | phenanthrolines | chelator;
copper chelator |
mefloquine hydrochloride
[no description available] | 2.04 | 1 | 0 | hydrochloride | |
formetamide
formetamide: RN given refers to cpd with unspecified isomeric designation | 2.15 | 1 | 0 | | |
isbufylline
isbufylline: RN from Toxlit | 2.15 | 1 | 0 | | |
toxoflavin
toxoflavin: azapteridine antibiotic; structure. toxoflavin : A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7. | 2.46 | 2 | 0 | carbonyl compound;
pyrimidotriazine | antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
toxin;
virulence factor;
Wnt signalling inhibitor |
7-chloro-4-hydroxyquinoline
7-chloro-4-hydroxyquinoline: structure given in first source | 6.96 | 1 | 0 | | |
phenylacetylglycine
phenylacetylglycine : A N-acylglycine that is glycine substituted on nitrogen with a phenylacetyl group. | 2.15 | 1 | 0 | monocarboxylic acid amide;
monocarboxylic acid;
N-acylglycine | human metabolite;
mouse metabolite |
4-aminoquinoline
[no description available] | 2.98 | 4 | 0 | | |
N-benzoylanthranilic acid
N-benzoylanthranilic acid : An amidobenzoic acid comprising benzoic acid having a benzamido group at the 2-position. | 2.15 | 1 | 0 | amidobenzoic acid | |
selfotel
selfotel: a N-methyl-D-aspartate (NMDA) antagonist; used to treat stroke-induced impairment | 2.04 | 1 | 0 | non-proteinogenic alpha-amino acid | |
artemisinin
(+)-artemisinin : A sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. | 2.1 | 1 | 0 | organic peroxide;
sesquiterpene lactone | antimalarial;
plant metabolite |
plasmenylserine
plasmenylserine: RN given refers to (L)-isomer. O-phospho-L-serine : The L-enantiomer of O-phosphoserine.. O-phosphoserine : A serine derivative that is serine substituted at the oxygen atom by a phosphono group. | 2.46 | 2 | 0 | O-phosphoserine | EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
quinocide
quinocide: Russian drug; RN given refers to parent cpd; structure | 2.06 | 1 | 0 | | |
butinoline
[no description available] | 2.15 | 1 | 0 | diarylmethane | |
n-(2-carboxyphenyl)glycine
[no description available] | 2.15 | 1 | 0 | | |
n,n-dimethyl-4-anisidine
[no description available] | 2.15 | 1 | 0 | | |
n-benzoylpiperidine
[no description available] | 2.15 | 1 | 0 | benzamides;
N-acylpiperidine | |
2-phenylcyclopropanecarboxylic acid
2-phenylcyclopropanecarboxylic acid: RN given for (trans)-isomer; structure in first source | 2.15 | 1 | 0 | | |
n-demethylantipyrine
[no description available] | 2.15 | 1 | 0 | pyrazoles;
ring assembly | |
3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine
[no description available] | 2.15 | 1 | 0 | 1,2,4-triazines | |
2-amino-5-bromopyridine
[no description available] | 2.15 | 1 | 0 | | |
2,2',2''-terpyridine
2,2',2''-terpyridine: RN given refers to parent cpd. 2,2':6',2''-terpyridine : A tridentate heterocyclic ligand that binds metals at three meridional sites giving two adjacent 5-membered MN2C2 chelate rings. | 2.46 | 2 | 0 | terpyridines | chelator |
n-benzoylalanine, (dl-ala)-isomer
[no description available] | 2.15 | 1 | 0 | alanine derivative;
N-acyl-amino acid | metabolite |
bicinchoninic acid
[no description available] | 2.15 | 1 | 0 | | |
clobetasone butyrate
[no description available] | 2.06 | 1 | 0 | organic molecular entity | |
betamipron
[no description available] | 2.15 | 1 | 0 | organonitrogen compound;
organooxygen compound | |
cletoquine
[no description available] | 2.46 | 2 | 0 | | |
jatrorrhizine
jatrorrhizine: isolated from bark of Enantia chlorantha (Annonaceae); structure given in first source | 2.06 | 1 | 0 | alkaloid | |
lycorine
lycorine: from bulbs of LYCORIS & other plants; RN given refers to (1 alpha,2 beta)-isomer; structure in Merck Index, 9th ed, #5444. lycorine : An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. | 2.46 | 2 | 0 | indolizidine alkaloid | anticoronaviral agent;
antimalarial;
plant metabolite;
protein synthesis inhibitor |
bathophenanthroline
4,7-diphenyl-1,10-phenanthroline : A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two phenyl substituents at positions 4 and 7. | 2.46 | 2 | 0 | benzenes;
phenanthrolines | chelator |
benzoylpropionic acid
benzoylpropionic acid: structure in first source. 4-oxo-4-phenylbutyric acid : A 4-oxo monocarboxylic acid that is butyric acid bearing oxo and phenyl substituents at position 4. | 2.15 | 1 | 0 | 4-oxo monocarboxylic acid | hapten |
fascaplysine
fascaplysine: from tropic sea sponges | 2.04 | 1 | 0 | | |
LSM-4272
[no description available] | 2.06 | 1 | 0 | beta-carbolines | |
Evoxine
[no description available] | 2.15 | 1 | 0 | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle | |
1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid
1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid: precursor of mutagenic nitroso cpd in soy sauce; structure given in first source | 2.15 | 1 | 0 | harmala alkaloid | |
tryptanthrine
tryptanthrine: minor constituent of traditional Chinese medicine qing dai | 2.46 | 2 | 0 | alkaloid antibiotic;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound | |
N-Benzylphthalimide
[no description available] | 2.15 | 1 | 0 | isoindoles | |
pyromellitic diimide
pyromellitic diimide: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
4'-bromosalicylanilide
4'-bromosalicylanilide: photoproduct from UV-irradiation of tribromsalan; structure | 2.15 | 1 | 0 | | |
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane: methoxychlor metabolite | 2.15 | 1 | 0 | bisphenol | |
terephthalamide
[no description available] | 2.15 | 1 | 0 | benzenedicarboxamide | |
3(2h)-pyridazinone, 4-chloro-5-(dimethylamino)-2-phenyl-
[no description available] | 2.15 | 1 | 0 | | |
2-nitrophenylacetic acid
(2-nitrophenyl)acetic acid : A member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the ortho- position by a nitro group. | 2.15 | 1 | 0 | C-nitro compound;
phenylacetic acids | |
onychine
[no description available] | 2.15 | 1 | 0 | | |
4'-methoxyflavone
4'-methoxyflavone: from seeds of Psoralea corylifolia (Fabaceae); structure in first source | 2.15 | 1 | 0 | ether;
flavonoids | |
1,3-diphenyl-2-aminopropane
1,3-diphenyl-2-aminopropane: structure given in the first source | 2.15 | 1 | 0 | | |
2,2-diphenylpropionic acid
2,2-diphenylpropionic acid: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
3,4-dimethoxyphenylacetamide
3,4-dimethoxyphenylacetamide: structure | 2.15 | 1 | 0 | | |
2-amino-5-bromobenzoic acid
2-amino-5-bromobenzoic acid: structure in first source | 2.15 | 1 | 0 | | |
2-(1H-benzimidazol-2-yl)aniline
2-(1H-benzimidazol-2-yl)aniline : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a 2-aminophenyl group at position 2. | 2.15 | 1 | 0 | benzimidazoles;
primary arylamine;
substituted aniline | geroprotector |
N-Acetylhomoveratrylamine
[no description available] | 2.15 | 1 | 0 | acetamides | |
2-chlorobenzenesulfonamide
[no description available] | 2.15 | 1 | 0 | | |
4-nitrophenyl dimethylcarbamate
[no description available] | 2.15 | 1 | 0 | | |
8-(4-tolylsulfonylamino)quinoline
8-(4-tolylsulfonylamino)quinoline: has diabetogenic properties; can be used for fluorometric determination of zinc; structure given in first source | 2.15 | 1 | 0 | sulfonamide | |
5-methoxyindole-3-carbaldehyde
[no description available] | 2.15 | 1 | 0 | indoles | |
2-oxo-1,2-dihydroquinoline-4-carboxylic acid
[no description available] | 2.15 | 1 | 0 | quinolinemonocarboxylic acid | |
5-chloroindole
5-chloroindole: a positive allosteric modulator of the 5-HT3 receptor | 3.51 | 1 | 0 | | |
6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one
[no description available] | 2.15 | 1 | 0 | beta-carbolines | |
ethylhydrocupreine
ethylhydrocupreine: structure; RN given refers to parent cpd. optochin : A cinchona alkaloid consisting of 10,11-dihydrocinchonan bearing hydroxy and ethoxy substituents at positions 9 and 6' respectively. | 2.46 | 2 | 0 | aromatic ether;
cinchona alkaloid | EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor |
pd 147953
[no description available] | 2.15 | 1 | 0 | | |
fenozan
fenozan: do not confuse with the phenothiazine phenosan | 2.15 | 1 | 0 | | |
2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine
2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine: RN given refers to parent cpd; structure given in first source | 2.06 | 1 | 0 | | |
5-phenylbarbituric acid
5-phenylbarbituric acid: RN given refers to parent cpd | 2.15 | 1 | 0 | | |
cinchonine
[no description available] | 2.46 | 2 | 0 | (8xi)-cinchonan-9-ol;
cinchona alkaloid | metabolite |
diethylpropion hydrochloride
diethylpropion hydrochloride : The hydrochloride salt of diethylpropion. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as an anoretic in the short term management of obesity. | 2.15 | 1 | 0 | hydrochloride | appetite depressant |
lupinine
lupinine: RN given refers to parent cpd(1R-trans)-isomer; structure | 2.07 | 1 | 0 | quinolizidine alkaloid | |
1-(4'-nitrophenyl)-2-aminopropane-1,3-diol
1-(4'-nitrophenyl)-2-aminopropane-1,3-diol: chloramphenicol minus dichloroacetamide side chain; RN given refers to cpd without isomeric designation | 2.15 | 1 | 0 | | |
beta-hydroxyphenylalanine
beta-hydroxyphenylalanine: RN given refers to beta cpd | 2.15 | 1 | 0 | | |
3-(n-salicyloyl)amino-1,2,4-triazole
3-(N-salicyloyl)amino-1,2,4-triazole: synthetic chelating agent used chiefly to inhibit corrosion of copper | 2.15 | 1 | 0 | | |
acridine-9-carboxylic acid
[no description available] | 2.15 | 1 | 0 | | |
1-phenazinecarboxylic acid
1-phenazinecarboxylic acid: from Streptomyces cinnamonensis; RN given refers to parent cpd; structure given in first source. phenazine-1-carboxylic acid : An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group. | 2.15 | 1 | 0 | aromatic carboxylic acid;
monocarboxylic acid;
phenazines | antifungal agent;
antimicrobial agent;
bacterial metabolite |
4,5-diphenyl-1,5-dihydroimidazol-2-one
[no description available] | 2.15 | 1 | 0 | stilbenoid | |
desethylchloroquine
desethylchloroquine: metabolite of chloroquine | 2 | 1 | 0 | aminoquinoline | |
2-hydroxy-1,2-bis(methoxyphenyl)ethanone
2-hydroxy-1,2-bis(methoxyphenyl)ethanone: structure given in first source | 2.15 | 1 | 0 | | |
mmv665852
MMV665852: an antischistosomal agent | 2.46 | 2 | 0 | | |
4-methyl-N-(phenylmethyl)benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4-n-butylaminobenzoic acid
4-n-butylaminobenzoic acid: degradation product of tetracaine. 4-(butylamino)benzoic acid : 4-Aminobenzoic acid in which one of the hydrogens attached to the nitrogen is substituted by a butyl group. | 2.15 | 1 | 0 | aromatic amino acid | |
1,3,4,10-Tetrahydro-9(2H)-acridinone
[no description available] | 2.46 | 2 | 0 | acridines | |
fluoren-9-ol
[no description available] | 2.15 | 1 | 0 | | |
1-(2-carboxyethyl)uracil
[no description available] | 2.15 | 1 | 0 | | |
1-benzylindole
1-benzylindole: structure | 2.15 | 1 | 0 | | |
2,3-bis(2-pyridinyl)quinoxaline
[no description available] | 2.15 | 1 | 0 | quinoxaline derivative | |
3,3',5,5'-tetrachlorobiphenyl-4,4'-diol
3,3',5,5'-tetrachlorobiphenyl-4,4'-diol : A member of the class of hydroxybiphenyls formed formally by chlorination of biphenyl-4,4'-diol at C-3, -3', -5 and -5'. | 2.15 | 1 | 0 | dichlorobenzene;
hydroxybiphenyls | |
5-nitro-2-(1-piperidinyl)pyridine
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
2-amino-5,7-dimethyl-1,8-naphthyridine
2-amino-5,7-dimethyl-1,8-naphthyridine: structure in first source | 2.15 | 1 | 0 | | |
5-benzyloxytryptophan
[no description available] | 2.15 | 1 | 0 | | |
2,5-diethoxy-4-morpholinoaniline
2,5-diethoxy-4-morpholinoaniline: structure in first source | 2.15 | 1 | 0 | | |
wr 158122
WR 158122: structure | 2.46 | 2 | 0 | | |
3-hydroxy-3-phenacyloxindole
[no description available] | 2.15 | 1 | 0 | | |
carbobenzoxyphenylalanine, (dl-phe)-isomer
[no description available] | 2.15 | 1 | 0 | | |
10-deazaaminopterin
[no description available] | 2.06 | 1 | 0 | | |
4-hydroxycarbazole
4-hydroxycarbazole: structure in first source | 2.01 | 1 | 0 | | |
dihydroergocristine
Dihydroergocristine: A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position of the molecule.. dihydroergocristine : Ergocristine in which a single bond replaces the double bond between positions 9 and 10. It is used as the mesylate salt for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. | 2.46 | 2 | 0 | ergot alkaloid | adrenergic antagonist;
vasodilator agent |
gamma-fagarine
gamma-fagarine: active alkaloid of Chinese medicines from Dictamni radicis cortex (Rutaceae); structure given in first source | 2.15 | 1 | 0 | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle | |
benzamil
[no description available] | 2.06 | 1 | 0 | guanidines;
pyrazines | |
3',4'-dichlorobenzamil
3',4'-dichlorobenzamil: inhibits Na-Ca exchange in membrane vesicle & papillary muscle preparations from guinea pig heart | 2.46 | 2 | 0 | guanidines;
pyrazines | |
cleistanthin b
cleistanthin B: toxic constituent of Cleistanthus collinus. cleistanthin B : A member of the class of cleistanthins that is cleistanthin A in which the 3,4-di-O-methyl-D-xylopyranosyl group is replaced by a beta-D-glucopyranosyl group. | 2.46 | 2 | 0 | beta-D-glucoside;
cleistanthins;
monosaccharide derivative | alpha-adrenergic antagonist;
antihypertensive agent;
diuretic |
3-carboxymethyl-6-benzyl-2,5-diketopiperazine
3-carboxymethyl-6-benzyl-2,5-diketopiperazine: formed in aqueous solution by aspartame; structure given in first source | 2.15 | 1 | 0 | organonitrogen compound;
organooxygen compound | |
parecoxib
parecoxib: structure in first source. parecoxib : An N-acylsulfonamide resulting from the formal condensation of valdecoxib with propionic acid. It is a prodrug for valdecoxib. | 3.51 | 1 | 0 | isoxazoles;
N-sulfonylcarboxamide | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug |
4-fluorobenzenesulfonamide
4-fluorobenzenesulfonamide: structure given in first source | 2.15 | 1 | 0 | | |
n-acetyltyramine
N-acetyltyramine: structure given in first source. N-acetyltyramine : A member of the class of tyramines that is tyramine in which one of the hydrogens of the amino group is replaced by an acetyl group. | 2.46 | 2 | 0 | acetamides;
tyramines | animal metabolite;
Aspergillus metabolite;
bacterial metabolite;
marine metabolite;
quorum sensing inhibitor |
emoxypine succinate
emoxypine succinate: has antihypoxic effects | 2.15 | 1 | 0 | | |
1,3-di(4-imidazolinophenoxyl)propane
1,3-di(4-imidazolinophenoxyl)propane: structure given in first source | 2.46 | 2 | 0 | | |
n-carbamyltryptophan
N-carbamyltryptophan: RN given refers to (D)-isomer | 2.15 | 1 | 0 | | |
2,4,6-trimethoxyacetophenone
2,4,6-trimethoxyacetophenone: structure in first source | 2.15 | 1 | 0 | | |
1-(2-hydroxyethyl)-3,5-diphenyl-1h-pyrazole
1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole: structure given in first source | 2.15 | 1 | 0 | | |
4-methyoxybenzoyl-n-glycine
[no description available] | 2.15 | 1 | 0 | N-acylglycine | |
5-ethoxy-2-ethylmercaptobenzimidazole
5-ethoxy-2-ethylmercaptobenzimidazole: has activating effect on peritoneal macrophages; RN given does not give position for ethoxy group | 2.15 | 1 | 0 | | |
7h-pyrido(4,3-c)carbazole
7H-pyrido(4,3-c)carbazole: structure given in first source | 2.46 | 2 | 0 | | |
5(6)-1(2h)-phthalazinonyl-4(1h)-benzimidazole-2-carbamate methyl ester
[no description available] | 2.15 | 1 | 0 | | |
imiloxan
[no description available] | 2.06 | 1 | 0 | benzodioxine | |
cl 246738
3,6-bis(2-piperidinoethoxy)acridine trihydrochloride: immunomodulator; structure given in first source; RN given for tri-HCl | 2.46 | 2 | 0 | | |
n-phenyliminodiacetic acid
[no description available] | 2.15 | 1 | 0 | | |
teomorfolin
teomorfolin: structure given in first source | 2.15 | 1 | 0 | | |
1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanone
[no description available] | 2.15 | 1 | 0 | benzodioxoles | |
n-(aminocarbonyl)-2-chlorobenzenesulfonamide
[no description available] | 2.15 | 1 | 0 | | |
3-hydroxy-2-quinoxalinepropionic acid
[no description available] | 2.15 | 1 | 0 | | |
8-(methylsulfonylamino)quinoline
8-(methylsulfonylamino)quinoline: has diabetogenic properties; structure given in first source | 2.15 | 1 | 0 | | |
celastrol methyl ester
celastrol methyl ester: isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME | 2.46 | 2 | 0 | carboxylic ester | |
n(4)-acetylsulfamonomethoxine
N(4)-acetylsulfamonomethoxine: main urinary metabolite of sulfamonomethoxine in pigs | 2.15 | 1 | 0 | | |
epiberberine
epiberberine: isolated in plants of Coptis from China | 2.06 | 1 | 0 | | |
2-phenyl-4-oxohydroquinoline
2-phenyl-4-oxohydroquinoline: structure given in first source | 2.46 | 2 | 0 | | |
8-(4-benzenesulfonylamino)quinoline
8-(4-benzenesulfonylamino)quinoline: has diabetogenic properties; structure given in first source | 2.15 | 1 | 0 | | |
methindione
methindione: used in treatment of epilepsy; RN given refers to parent cpd; structure | 2.15 | 1 | 0 | | |
3,4-dihydroxybenzophenone
3,4-dihydroxybenzophenone: structure in first source | 2.15 | 1 | 0 | | |
gamma-propanol
[no description available] | 2.15 | 1 | 0 | | |
cypripedin
cypripedin: sensitizing agent for contact dermatitis from Lady Slipper (Cypripedium calceolus); structure | 2.46 | 2 | 0 | phenanthrol | |
2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile
[no description available] | 2.15 | 1 | 0 | benzenes;
nitrile | |
respinomycin d
respinomycin D: structure given in first source; isolated from Streptomyces xanthocidicus | 2.46 | 2 | 0 | | |
azacrin
azacrin: structure | 2.04 | 1 | 0 | | |
isonicotinylamide gaba
[no description available] | 2.15 | 1 | 0 | | |
5-fluorotryptamine monohydrochloride
[no description available] | 2.15 | 1 | 0 | | |
4-iodo-n-(2-(4-morpholinyl)ethyl)benzamide
4-iodo-N-(2-(4-morpholinyl)ethyl)benzamide: the iodinated analog of moclobemide; structure given in first source | 2.15 | 1 | 0 | | |
3-(hydroxyacetyl)indole
3-(hydroxyacetyl)indole: structure in first source | 2.15 | 1 | 0 | indoles | |
n-(4-aminophenylsulfonyl)morpholine
compound 82 208: structure given in first source | 2.15 | 1 | 0 | | |
1H-indol-3-yl-(4-methoxyphenyl)methanone
[no description available] | 2.15 | 1 | 0 | N-acylindole | |
2-amino-5-phenyl-1,3,4-thiadiazole
2-amino-5-phenyl-1,3,4-thiadiazole: structure in first source | 2.15 | 1 | 0 | | |
N-(1-phenylethyl)acetamide
N-(1-phenylethyl)acetamide : A member of the class of acetamides resulting from the formal condensation of the amino group of 1-phenylethylamine with 1 mol eq. of acetic acid. | 2.15 | 1 | 0 | acetamides;
secondary carboxamide | |
alpha-(trichloromethyl)-4-pyridineethanol
alpha-(trichloromethyl)-4-pyridineethanol: activates caspase-3 | 2.15 | 1 | 0 | pyridines | |
3-cyanoindole
[no description available] | 2.01 | 1 | 0 | | |
ml 204
ML 204: modulates both TRPC4 and TRPC5 channels; structure in first source | 2.15 | 1 | 0 | | |
acetoxycycloheximide
acetoxycycloheximide: structure | 2.46 | 2 | 0 | | |
eudesmin
eudesmin: RN refers to (1R-(1alpha,3aalpha,4alpha,6aalpha))-isomer; structure given in first source; very similar to pinoresinol | 2.15 | 1 | 0 | | |
(R)-Roemerine
[no description available] | 2.46 | 2 | 0 | isoquinoline alkaloid | |
2-amino-4-methyl-3-nitropyridine
[no description available] | 2.15 | 1 | 0 | | |
anisomycin
Anisomycin: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.. (-)-anisomycin : An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | 2.04 | 1 | 0 | monohydroxypyrrolidine;
organonitrogen heterocyclic antibiotic | anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
DNA synthesis inhibitor;
protein synthesis inhibitor |
4,4-bis(hydroxymethyl)-2-phenyl-2-oxazoline
4,4-bis(hydroxymethyl)-2-phenyl-2-oxazoline: Anticonvulsant | 2.15 | 1 | 0 | | |
n-acetylhistidine
[no description available] | 2.15 | 1 | 0 | histidine derivative;
N-acetyl-amino acid | |
1-(1-oxo-2-phenylethyl)-4-piperidinecarboxylic acid
[no description available] | 2.15 | 1 | 0 | acetamides | |
1-(4-chlorophenyl)-3-(2-ethoxyphenyl)urea
[no description available] | 2.15 | 1 | 0 | ureas | |
4-methoxyxanthone
4-methoxyxanthone: a vasodilator; structure in first source | 2.15 | 1 | 0 | | |
N-(4-nitrophenyl)-2-phenoxyacetamide
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
1-phenylindolin-2-one
1-phenylindolin-2-one: structure in first source | 2.15 | 1 | 0 | | |
1-(benzenesulfonyl)indole
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
2,4,4,6-Tetramethyl-1,4-dihydro-3,5-pyridinedicarbonitrile
[no description available] | 2.15 | 1 | 0 | dihydropyridine | |
pifithrin mu
2-phenylacetylenesulfonamide: induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia cells; also inhibits Hsp70 and autophagy | 2.15 | 1 | 0 | benzenes | |
2-benzyloxybenzaldehyde
[no description available] | 2.15 | 1 | 0 | | |
2-guanidine-4-methylquinazoline
2-guanidine-4-methylquinazoline: structure given in first source | 2.77 | 3 | 0 | | |
N-phenylcarbamic acid 2-phenoxyethyl ester
[no description available] | 2.15 | 1 | 0 | carbamate ester | |
jatrorrhizine chloride
[no description available] | 2.04 | 1 | 0 | | |
3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
mensacarcin
mensacarcin: structure in first source | 2.06 | 1 | 0 | | |
mequindox
Mequindox: a synthetic quinoxaline 1,4-dioxide derivative which can effectively improve growth and feed efficiency in animals; structure in first source | 2.15 | 1 | 0 | | |
N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide
[no description available] | 2.15 | 1 | 0 | diarylmethane | |
puromycin
[no description available] | 2.46 | 2 | 0 | puromycins | antiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor |
quinidine
Quinidine: An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.. quinidine : A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. | 2.76 | 3 | 0 | cinchona alkaloid | alpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker |
cephaelin
cephaelin: do not confuse with cephalin of brain; after emetine this is the most important alkaloid of ipecac; protein synthesis inhibitor. cephaeline : A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions. | 2.06 | 1 | 0 | pyridoisoquinoline | |
Girgensonine
[no description available] | 2.15 | 1 | 0 | nitrile | |
Dubinidine
[no description available] | 2.15 | 1 | 0 | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle | |
trichostatin a
trichostatin A: chelates zinc ion in the active site of histone deacetylases, resulting in preventing histone unpacking so DNA is less available for transcription; do not confuse with TRICHOSANTHIN which is a protein; found in STREPTOMYCES | 2.04 | 1 | 0 | antibiotic antifungal agent;
hydroxamic acid;
trichostatin | bacterial metabolite;
EC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector |
arachidonic acid
icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid. | 3.51 | 1 | 0 | icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid | Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite |
docosahexaenoate
efalex: a mixture of fish oil and primrose oil; used as a high-docosahexaenoic acid fatty acid supplement. docosahexaenoic acid : Any C22 polyunsaturated fatty acid containing six double bonds.. docosahexaenoate : A polyunsaturated fatty acid anion that is the conjugate base of docosahexaenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.. all-cis-docosa-4,7,10,13,16,19-hexaenoic acid : A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19. | 3.51 | 1 | 0 | docosahexaenoic acid;
omega-3 fatty acid | algal metabolite;
antineoplastic agent;
Daphnia tenebrosa metabolite;
human metabolite;
mouse metabolite;
nutraceutical |
oleic acid
Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed). oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry. | 3.51 | 1 | 0 | octadec-9-enoic acid | antioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent |
(3R,5S)-fluvastatin
(3R,5S)-fluvastatin : A (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid diastereoisomer in which the stereocentres beta- and delta- to the carboxy group have R and S configuration, respectively. The drug fluvastatin is an equimolar mixture of this compound and its enantiomer. | 3.51 | 1 | 0 | (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid;
statin (synthetic) | |
mycophenolic acid
Mycophenolic Acid: Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.. mycophenolate : A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid.. mycophenolic acid : A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases. | 2.01 | 1 | 0 | 2-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols | anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic |
epothilone b
[no description available] | 2.46 | 2 | 0 | epothilone;
epoxide | antineoplastic agent;
apoptosis inducer;
microtubule-stabilising agent |
wr-142,490
(+)-(11R,2'S)-erythro-mefloquine : An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown. | 2.06 | 1 | 0 | [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol | antimalarial |
dactinomycin
Dactinomycin: A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) | 2.46 | 2 | 0 | actinomycin | mutagen |
N-[4-(methanesulfonamido)phenyl]acetamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
[no description available] | 2.46 | 2 | 0 | pyrimidotriazine | |
4-(2-oxazolo[4,5-b]pyridinyl)aniline
[no description available] | 2.15 | 1 | 0 | 1,3-oxazoles | |
2-[(4-nitrophenyl)methylthio]-1,3-benzoxazole
[no description available] | 2.15 | 1 | 0 | benzoxazole | |
jp-1302
[no description available] | 2.46 | 2 | 0 | | |
3-oxido-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium
[no description available] | 2.15 | 1 | 0 | pyridazines | |
3-(2,4-difluoroanilino)-5,5-dimethyl-1-cyclohex-2-enone
[no description available] | 2.15 | 1 | 0 | substituted aniline | |
1-phenyl-4-pyrazolol
[no description available] | 2.15 | 1 | 0 | pyrazoles;
ring assembly | |
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide
[no description available] | 2.15 | 1 | 0 | benzothiazoles | |
3-benzamido-2-benzofurancarboxamide
[no description available] | 2.15 | 1 | 0 | benzofurans | |
N-[2-(4-methoxyphenyl)ethyl]acetamide
[no description available] | 2.15 | 1 | 0 | acetamides | |
N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
methyl indole-3-carboxylate
methyl indole-3-carboxylate : The methyl ester of indole-3-carboxylic acid. | 3.51 | 1 | 0 | indoles;
methyl ester | metabolite |
2-(1H-indol-3-ylthio)acetic acid
[no description available] | 2.15 | 1 | 0 | indoles | |
3-bromo-N-[2-(4-nitroanilino)ethyl]benzamide
[no description available] | 2.15 | 1 | 0 | carbonyl compound;
organohalogen compound | |
3-Methylbenzofuran-2-carboxylic acid
[no description available] | 2.15 | 1 | 0 | benzofurans | |
5-(3,4-dimethoxyphenyl)-2H-tetrazole
[no description available] | 2.15 | 1 | 0 | tetrazoles | |
1-(4-fluorophenyl)sulfonyl-4-(2-methoxyphenyl)piperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
4-[[bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol
[no description available] | 2.15 | 1 | 0 | alkylbenzene | |
2-phenylindole-3-carbaldehyde
2-phenylindole-3-carbaldehyde: structure in first source | 2.15 | 1 | 0 | | |
4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine
[no description available] | 2.15 | 1 | 0 | aryl sulfide | |
5-(4-nitrophenyl)-4-phenyl-2-thiazolamine
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
3-[6-(4-aminophenyl)-2-phenyl-4-pyrimidinyl]aniline
[no description available] | 2.15 | 1 | 0 | pyrimidines | |
7-hydroxy-2-methoxy-1,4-phenanthrenedione
7-hydroxy-2-methoxy-1,4-phenanthrenedione: structure in first source; from Dendrobium densiflorum | 2.46 | 2 | 0 | | |
7-methoxyisoflavone
7-methoxyisoflavone : A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 7. | 2.15 | 1 | 0 | 7-methoxyisoflavones | |
cgp 60474
[no description available] | 2.46 | 2 | 0 | substituted aniline | |
LSM-32392
[no description available] | 2.15 | 1 | 0 | monoterpenoid | |
N-[2-(1-cyclohexenyl)ethyl]-4-(4-morpholinylmethyl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
N-[2-(2-furanylmethylthio)ethyl]-4-methoxybenzenesulfonamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
3-acetamido-5-chloro-2-benzofurancarboxylic acid
[no description available] | 2.15 | 1 | 0 | benzofurans | |
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(2,6-dimethoxyphenyl)methanone
[no description available] | 2.15 | 1 | 0 | dimethoxybenzene | |
4-[4-methyl-6-(4-methyl-1-piperazinyl)-2-pyrimidinyl]morpholine
[no description available] | 2.15 | 1 | 0 | N-arylpiperazine | |
haplamine
haplamine: isolated from Haplophyllum acutifolium; structure in first source | 2.15 | 1 | 0 | organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle | |
5-(3,4-dimethoxyphenyl)-1H-1,2,4-triazol-3-amine
[no description available] | 2.15 | 1 | 0 | triazoles | |
2-ethoxy-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol
[no description available] | 2.06 | 1 | 0 | alkylbenzene | |
2-[2-hydroxy-6,7-dimethoxy-4-(4-morpholinyl)-1-naphthalenyl]-N-phenylacetamide
[no description available] | 2.46 | 2 | 0 | naphthols | |
1-ethyl-6-methoxy-4-oxo-3-quinolinecarboxylic acid
[no description available] | 2.15 | 1 | 0 | quinolines | |
2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline
2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline : A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by pyridin-4-yl and pyrrolidin-1-yl groups, respectively. | 2.15 | 1 | 0 | pyridines;
pyrrolidines;
quinazolines | |
scp 1
[no description available] | 2.15 | 1 | 0 | | |
N-(3-acetamidophenyl)-4-methoxybenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-(3-acetamidophenyl)-3-chlorobenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
4-methoxy-N-(5-methyl-3-isoxazolyl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-(2-fluorophenyl)-4-phenylmethoxybenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-[4-(diethylamino)phenyl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
N-(2-furanylmethyl)-2-benzofurancarboxamide
[no description available] | 2.15 | 1 | 0 | benzofurans | |
5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine
[no description available] | 2.15 | 1 | 0 | aromatic amine;
thiadiazoles | |
te 5
[no description available] | 2.15 | 1 | 0 | | |
2-[[anilino(oxo)methyl]amino]-4,5-dimethyl-3-thiophenecarboxamide
[no description available] | 2.15 | 1 | 0 | ureas | |
N-(4,6-dimethyl-2-pyrimidinyl)-1,3-benzothiazol-2-amine
[no description available] | 2.15 | 1 | 0 | benzothiazoles | |
6-methylflavone
6-methylflavone: structure in first source | 2.15 | 1 | 0 | | |
2-methoxy-N-(2-pyridinyl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
2-chloro-N-(2-phenylethyl)benzamide
[no description available] | 2.15 | 1 | 0 | carbonyl compound;
organohalogen compound | |
N1-(4H-1,2,4-triazol-4-yl)-4-nitrobenzamide
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
N-[2-(1-cyclohexenyl)ethyl]-4-fluorobenzamide
[no description available] | 2.15 | 1 | 0 | carbonyl compound;
organohalogen compound | |
tioxazafen
tioxazafen : A 1,2,4-oxadizole in which the hydrogens at positions 3 and 5 have been replaced by phenyl and thiophen-2-yl groups, respectively. It is used as a broad spectrum nematicidal seed treatment. | 2.15 | 1 | 0 | 1,2,4-oxadiazole;
thiophenes | agrochemical;
nematicide |
N4-(3-chlorophenyl)-6-methyl-N2-(phenylmethyl)pyrimidine-2,4-diamine
[no description available] | 2.46 | 2 | 0 | aralkylamine | |
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
1-(4-Methoxyphenyl)-2-nitroethylene
4-methoxy-beta-nitrostyrene: has vasodilator activity; structure in first source | 2.15 | 1 | 0 | methoxybenzenes | |
brd32048
BRD32048: inhibits ETV1 oncoprotein; structure in first source | 2.15 | 1 | 0 | methoxybenzenes;
substituted aniline | |
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
n-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine
N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine: calcium-activated small conductance potassium channels inhibitor; structure in first source | 2.06 | 1 | 0 | | |
2-(3,4-dichlorophenyl)imidazo[1,2-a]pyrimidine
[no description available] | 2.15 | 1 | 0 | imidazoles | |
5-(2-phenyl-4-triazolyl)-2H-tetrazole
[no description available] | 2.15 | 1 | 0 | triazoles | |
N-cyclohexyl-2,3-dihydroindole-1-carboxamide
[no description available] | 2.15 | 1 | 0 | indolyl carboxylic acid | |
4-(benzylsulfanyl)thieno[2,3-d]pyrimidine
4-(benzylsulfanyl)thieno[2,3-d]pyrimidine : A thienopyrimidine that is thieno[2,3-d]pyrimidine which is substituted at position 4 by a benzylsulfanediyl group. | 2.15 | 1 | 0 | aryl sulfide;
benzenes;
thienopyrimidine | |
2-methyl-5-(5-methyl-2-furanyl)-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinone
[no description available] | 2.15 | 1 | 0 | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamide
[no description available] | 2.15 | 1 | 0 | indolecarboxamide | |
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methoxybenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
4-(1H-benzimidazol-2-yl)quinoline
[no description available] | 2.15 | 1 | 0 | quinolines | |
1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
N-(2,5-dimethylphenyl)-2-benzofurancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
N-(4-methoxyphenyl)-2-benzofurancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
2-(9h-xanthen-9-yl)-malonic acid
[no description available] | 2.15 | 1 | 0 | xanthenes | |
1-(1,3-benzothiazol-2-yl)-3-phenylurea
[no description available] | 2.15 | 1 | 0 | ureas | |
1-hydroxy-2-phenyl-1,5,6,7-tetrahydro-4H-benzimidazol-4-one
[no description available] | 2.15 | 1 | 0 | imidazoles | |
N-(4-acetamidophenyl)-2-bromobenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
4-bromo-N-phenacylbenzamide
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone
[no description available] | 2.15 | 1 | 0 | indoles | |
N-[6-methyl-2-(4-methylphenyl)-5-benzotriazolyl]-3-pyridinecarboxamide
[no description available] | 2.15 | 1 | 0 | triazoles | |
N,N-dimethyl-N'-p-tolylsulfamide
N,N-dimethyl-N'-p-tolylsulfamide : A member of the class of sulfamides that is N,N-dimethylsulfuric diamide substituted by a 4-methylphenyl group at the amino nitrogen atom. It is a metabolite of the agrochemical tolylfluanid. | 2.15 | 1 | 0 | sulfamides | marine xenobiotic metabolite |
2-(1-piperidinylmethyl)phenol
2-(1-piperidinylmethyl)phenol: structure in first source | 2.15 | 1 | 0 | | |
2,6-bis(benzimidazol-2-yl)pyridine
2,6-bis(benzimidazol-2-yl)pyridine: structure in first source | 2.77 | 3 | 0 | benzimidazoles | |
1-cyclohexyl-3-(2-phenylethyl)urea
[no description available] | 2.15 | 1 | 0 | benzenes | |
1-(3,5-dichlorophenyl)-3-phenylurea
[no description available] | 2.15 | 1 | 0 | ureas | |
1-(cyclohexylmethyl)-4-phenylpiperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
N-phenethyl-2-furamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
heteroarene | |
paromomycin sulfate
[no description available] | 2.15 | 1 | 0 | | |
N,N,2-trimethyl-1-phenyl-5-benzimidazolesulfonamide
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
N-(phenylmethyl)-4-(3-pyridinyl)-2-thiazolamine
[no description available] | 2.15 | 1 | 0 | aralkylamine | |
N-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | monoterpenoid | |
2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile
[no description available] | 2.15 | 1 | 0 | nitrile;
pyridines | |
2-ethoxy-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
vu0099704
VU0099704: an antagonist of protease activated receptor 4 (PAR-4); structure in first source | 2.15 | 1 | 0 | | |
3-(4-chlorophenyl)-2,5-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
[no description available] | 2.15 | 1 | 0 | pyrazoles;
ring assembly | |
1-(2-chloro-6-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoline
[no description available] | 2.15 | 1 | 0 | triazoles | |
2-methyl-N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)propanamide
[no description available] | 2.15 | 1 | 0 | pyrroloquinoline | |
2-methyl-5-[(2-methyl-4-quinolinyl)thio]-1,3,4-thiadiazole
[no description available] | 2.15 | 1 | 0 | aryl sulfide | |
5-methyl-1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1h-pyrido(3,2-b)indole-3-carbonitrile
VRX-413638: structure in first source | 2.15 | 1 | 0 | | |
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
2-fluoro-N-phenacylbenzamide
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile
[no description available] | 2.15 | 1 | 0 | nitrile;
pyridines | |
1-azepanyl-[2-methoxy-4-(methylthio)phenyl]methanone
[no description available] | 2.15 | 1 | 0 | carbonyl compound;
thiol | |
GS4012 free base
GS4012 free base : A member of the class of pyridines that is 2-(pyridin-4-yl)ethane-1-thiol in which the thiol hydrogen is replaced by a 4-methoxyphenyl group. | 2.15 | 1 | 0 | aryl sulfide;
monomethoxybenzene;
pyridines | VEGF activator |
N-[1-(4-methylphenyl)-5-benzimidazolyl]acetamide
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
2-(4-methylanilino)-1-(4-nitrophenyl)ethanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide
N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide : An amino acid amide obtained by the formal condensation of 2,6-dimethylaniline with N-(3,5-dimethylphenyl)glycine. | 2.15 | 1 | 0 | amino acid amide;
glycine derivative | |
2-[4-[(3-fluorophenyl)methyl]-1-piperazinyl]pyrimidine
[no description available] | 2.15 | 1 | 0 | N-arylpiperazine | |
1-[(3,4-dimethoxyphenyl)methyl]-4-(2,3-dimethylphenyl)piperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
4-Piperidinobenzoic acid
[no description available] | 2.15 | 1 | 0 | piperidines | |
1-(2-methoxyphenyl)-4-(3-thiophenylmethyl)piperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-(1-pyrrolidinyl)acetamide
[no description available] | 2.15 | 1 | 0 | pyrroloquinoline | |
4-[(1H-benzimidazol-2-ylthio)methyl]-2-thiazolamine
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
N-[7-(1-oxopropyl)-2,3-dihydro-1,4-benzodioxin-6-yl]benzamide
[no description available] | 2.15 | 1 | 0 | benzodioxine | |
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
n-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine
N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine: an SK channel inhibitor | 2.77 | 3 | 0 | | |
8-(3,5-dimethyl-1-pyrazolyl)quinoline
[no description available] | 2.15 | 1 | 0 | quinolines | |
2'-nitroflavone
2'-nitroflavone: has antineoplastic activity | 2.15 | 1 | 0 | | |
N-(4-methoxyphenyl)-3,4-dihydroquinolin-2-amine
[no description available] | 2.15 | 1 | 0 | aminoquinoline | |
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
[no description available] | 2.15 | 1 | 0 | aromatic compound | |
vrt 532
VRT 532: a CFTR potentiator; structure in first source | 2.15 | 1 | 0 | | |
4-[[4-(2,5-dimethylphenyl)-1-piperazinyl]methyl]-2-methoxyphenol
[no description available] | 2.15 | 1 | 0 | piperazines | |
1-piperonylpiperidine
1-piperonylpiperidine: an AMPA receptor modulator; structure in first source | 2.15 | 1 | 0 | | |
2-[(3-fluorophenyl)methyl-(phenylmethyl)amino]ethanol
[no description available] | 2.15 | 1 | 0 | aromatic amine | |
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenol
[no description available] | 2.15 | 1 | 0 | aromatic amine | |
6-ethyl-5-methyl-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
[no description available] | 2.15 | 1 | 0 | pyrazolopyrimidine | |
N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-(6-phenyl-5-imidazo[2,1-b]thiazolyl)benzamide
[no description available] | 2.15 | 1 | 0 | imidazoles | |
2-(phenylmethylthio)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
[no description available] | 2.15 | 1 | 0 | aryl sulfide | |
5-methyl-N-(4,5,6-trimethyl-2-pyrimidinyl)-1,3-benzoxazol-2-amine
[no description available] | 2.15 | 1 | 0 | benzoxazole | |
1-(4-methoxyphenyl)-3-(6-methyl-2-pyridinyl)urea
[no description available] | 2.15 | 1 | 0 | ureas | |
2-{[hydroxy(2-methoxyphenyl)methylidene]amino}acetic acid
[no description available] | 2.15 | 1 | 0 | N-acylglycine | |
(4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
N-(3-acetamidophenyl)-2-chlorobenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamine
[no description available] | 2.15 | 1 | 0 | dialkylarylamine;
tertiary amino compound | |
2-bromo-N-(3-methoxyphenyl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-[4-(1-azepanyl)phenyl]-2-chloroacetamide
[no description available] | 2.46 | 2 | 0 | anilide | |
2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol
[no description available] | 2.15 | 1 | 0 | aromatic ether;
C-nitro compound | |
3-[[(2,5-dimethyl-3-furanyl)-oxomethyl]amino]benzoic acid
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
1-(4-ethoxyphenyl)-3-(6-quinoxalinyl)urea
[no description available] | 2.15 | 1 | 0 | quinoxaline derivative | |
2-(dimethylsulfamoylamino)-9H-fluorene
[no description available] | 2.15 | 1 | 0 | fluorenes | |
4-chloro-1-ethyl-3-nitro-2-quinolinone
[no description available] | 2.15 | 1 | 0 | nitro compound;
quinolines | |
4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone
[no description available] | 2.15 | 1 | 0 | quinolines | |
2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde
[no description available] | 2.15 | 1 | 0 | arenecarbaldehyde | |
2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone
[no description available] | 2.15 | 1 | 0 | stilbenoid | |
4-methyl-N-(3-nitrophenyl)-5-phenyl-3-thiophenecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
N-(5-amino-1-phenyl-1,2,4-triazol-3-yl)-2,2,2-trichloroacetamide
[no description available] | 2.15 | 1 | 0 | triazoles | |
N-(2-fluoro-5-methylphenyl)-3-phenylpropanamide
[no description available] | 2.15 | 1 | 0 | anilide | |
N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide
[no description available] | 2.15 | 1 | 0 | organofluorine compound | |
4-tert-butyl-N-(1,4-dioxo-2,3-dihydrophthalazin-5-yl)benzamide
[no description available] | 2.15 | 1 | 0 | phthalazines | |
N-[2-(2-methylpropyl)-1,3-dioxo-5-isoindolyl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | phthalimides | |
6-(1,4,5,7-tetramethyl-6-pyrrolo[3,4-d]pyridazinyl)quinoline
[no description available] | 2.15 | 1 | 0 | quinolines | |
2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone
[no description available] | 2.15 | 1 | 0 | stilbenoid | |
5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole
[no description available] | 2.15 | 1 | 0 | oxadiazole;
ring assembly | |
5-(phenylmethyl)-3-(2-pyridinyl)-1,2,4-oxadiazole
[no description available] | 2.15 | 1 | 0 | pyridines | |
2-methyl-5-(1-pyrrolidinyl)isoindole-1,3-dione
[no description available] | 2.15 | 1 | 0 | phthalimides | |
N-(4-methylphenyl)carbamic acid (cyclopentylideneamino) ester
[no description available] | 2.46 | 2 | 0 | toluenes | |
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)
[no description available] | 2.77 | 3 | 0 | benzimidazoles | |
N-(4-bromo-2-fluorophenyl)-2-methyl-3-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
6,7,8,9-tetrahydro-5H-carbazole-3-carbohydrazide
[no description available] | 2.15 | 1 | 0 | carbazoles | |
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamide
[no description available] | 2.15 | 1 | 0 | primary carboxamide;
pyrazines;
secondary carboxamide | |
N-(1,3-benzodioxol-5-yl)-5-methyl-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | benzodioxoles | |
1-cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea
[no description available] | 2.15 | 1 | 0 | benzodioxine | |
8-[(2-methyl-5-nitro-1,2,4-triazol-3-yl)thio]quinoline
[no description available] | 2.15 | 1 | 0 | aryl sulfide | |
1-[2-(2-chlorophenoxy)ethyl]benzimidazole
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
4,5-dimethyl-2-[4-(3-nitrophenyl)-2-thiazolyl]-1H-pyrazol-3-one
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
2-(4-fluoro-N-methylsulfonylanilino)-N-(3-methylphenyl)acetamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
1,4,8-trimethyl-12-quinolino[2,3-b]quinolinamine
[no description available] | 2.46 | 2 | 0 | aminoquinoline | |
1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
3-methyl-6-(1-pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazine
[no description available] | 2.15 | 1 | 0 | triazolopyridazine | |
N-(3-acetylphenyl)-2-thiophen-2-ylacetamide
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
oncrasin-1
oncrasin-1: an antineoplastic agent; structure in first source. oncrasin-1 : A member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations. | 2.15 | 1 | 0 | arenecarbaldehyde;
indoles;
monochlorobenzenes | antineoplastic agent;
apoptosis inducer |
N-[2-(4-fluorophenyl)ethyl]-4-nitrobenzamide
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
N-(4-anilinophenyl)-2-methylpropanamide
[no description available] | 2.15 | 1 | 0 | anilide | |
N-(2-fluorophenyl)-3-phenylpropanamide
[no description available] | 2.15 | 1 | 0 | anilide | |
1-[(Phenylthio)acetyl]piperidine
[no description available] | 2.15 | 1 | 0 | N-acylpiperidine | |
N-(3-hydroxyphenyl)-5-methyl-3-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole
[no description available] | 2.15 | 1 | 0 | oxadiazole;
ring assembly | |
4-[(4-carboxy-2,6-dimethoxyphenoxy)methyl]-5-methyl-2-furancarboxylic acid
[no description available] | 2.15 | 1 | 0 | trihydroxybenzoic acid | |
4-(4-morpholinylmethyl)-3-quinolinol
[no description available] | 2.15 | 1 | 0 | quinolines | |
2-bromo-N-[3-(1-oxopropylamino)phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
3-acetyl-2-methylbenzo[f]benzofuran-4,9-dione
[no description available] | 2.15 | 1 | 0 | naphthofuran | |
5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
heteroarene | |
1-azepanyl-[4-[(phenylthio)methyl]phenyl]methanone
[no description available] | 2.15 | 1 | 0 | benzamides | |
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-nitrophenyl)acetamide
[no description available] | 2.15 | 1 | 0 | acetamides | |
3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
1-propylsulfonyl-4-(2-pyridinyl)piperazine
[no description available] | 2.15 | 1 | 0 | piperazines;
pyridines | |
2-(2-phenylethylthio)-3-pyridinecarboxylic acid
[no description available] | 2.15 | 1 | 0 | aromatic carboxylic acid;
pyridines | |
2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
2-[[anilino(oxo)methyl]amino]-N-(phenylmethyl)benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | thiazoles | |
1-cyclohexyl-3-(3-ethylphenyl)urea
[no description available] | 2.15 | 1 | 0 | ureas | |
n-phenylpiracetam
N-phenylpiracetam: structure given in first source | 2.15 | 1 | 0 | | |
2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide
[no description available] | 2.15 | 1 | 0 | biphenyls | |
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-nitrobenzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(2,6-dimethylphenyl)benzamide
[no description available] | 2.15 | 1 | 0 | isoquinolines | |
5-(4-bromophenyl)-N-(2-methoxyphenyl)-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
3-[[(3,5-dichloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid
[no description available] | 2.15 | 1 | 0 | benzamides | |
1,4-bis(thiophen-2-ylsulfonyl)piperazine
[no description available] | 2.15 | 1 | 0 | N-sulfonylpiperazine;
thiophenes | |
2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
1-(2-fluorophenyl)-4-[(6-nitro-1,3-benzodioxol-5-yl)methyl]piperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
n-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide
N-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide: inhibits the betaine-GABA transporter 1; structure in first source | 2.15 | 1 | 0 | | |
2-[[2-(5-methyl-2-thiophenyl)-2-oxoethyl]thio]-3-phenyl-4-quinazolinone
[no description available] | 2.15 | 1 | 0 | quinazolines | |
1-(2,1,3-benzothiadiazol-5-yl)-3-[4-(4-morpholinyl)phenyl]urea
[no description available] | 2.15 | 1 | 0 | morpholines | |
ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate
ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate : A sulfonamide in which the nitrogen carries methyl and 2-[4-(ethoxycarbonyl)piperazin-1-yl]-2-oxoethyl substituents and the sulfonyl a 4-chlorophenyl group. | 2.15 | 1 | 0 | carbamate ester;
sulfonamide | |
LSM-4563
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
1-(4-chloro-3-methoxyphenyl)sulfonyl-4-phenylpiperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
N-[4-[(3,4-dimethoxyphenyl)sulfamoyl]phenyl]acetamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
1-(2,5-dimethoxyphenyl)sulfonyl-4-(phenylmethyl)piperazine
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
2-furanyl-(4,4,8-trimethyl-1-sulfanylidene-5-dithiolo[3,4-c]quinolinyl)methanone
[no description available] | 2.46 | 2 | 0 | aromatic amide;
heteroarene | |
2-(4-methoxyphenyl)-N-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]acetamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4-[4-(benzenesulfonyl)-1-piperazinyl]-2-methylquinoline
[no description available] | 2.15 | 1 | 0 | piperazines;
pyridines | |
1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanone
[no description available] | 2.77 | 3 | 0 | quinolines | |
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine
[no description available] | 2.15 | 1 | 0 | tetrazoles | |
2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-(4,5-diphenyl-2-oxazolyl)acetamide
[no description available] | 2.15 | 1 | 0 | 1,3-oxazoles | |
2-(4-bromophenyl)-1-[4-(2-pyridinyl)-1-piperazinyl]ethanone
[no description available] | 2.15 | 1 | 0 | piperazines;
pyridines | |
2-amino[1,3]thiazolo[4,5-d]pyrimidine-5,7-diol
[no description available] | 2.15 | 1 | 0 | thiazolopyrimidine | |
3-[[(2-cyclohexyl-1,3-dioxo-5-isoindolyl)-oxomethyl]amino]benzoic acid
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
3-[[[3-(1-azepanylsulfonyl)-4-chlorophenyl]-oxomethyl]amino]benzoic acid
[no description available] | 2.15 | 1 | 0 | benzamides | |
2-(4-bromophenyl)-N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)acetamide
[no description available] | 2.15 | 1 | 0 | acetamides | |
5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid
[no description available] | 2.15 | 1 | 0 | methoxybenzoic acid | |
N-cycloheptyl-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
N-[3-[[(4-nitrophenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
N-(2-methyl-1,3-benzothiazol-6-yl)-4-(4-morpholinylsulfonyl)benzamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4-(dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
3-chloro-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
N-(3,4-dimethoxyphenyl)-4-[(4-phenyl-1-piperazinyl)methyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
stk295900
[no description available] | 2.77 | 3 | 0 | | |
1-(3-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine
[no description available] | 2.15 | 1 | 0 | piperazines | |
2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide
[no description available] | 2.15 | 1 | 0 | pyridazines;
ring assembly | |
1-(2-fluorophenyl)-3-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]urea
[no description available] | 2.15 | 1 | 0 | ureas | |
N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | methoxybenzenes | |
N-(1,3-benzodioxol-5-yl)-4-methyl-1-phthalazinamine
[no description available] | 2.15 | 1 | 0 | phthalazines | |
6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazole
[no description available] | 2.46 | 2 | 0 | benzimidazoles | |
SMER 28
SMER 28 : A member of the class of quinazolines that is quinazoline which is substituted by a prop-2-en-1-ylnitrilo group and a bromo group at positions 4 and 6, respectively. It is a modulator of mammalian autophagy. | 2.15 | 1 | 0 | organobromine compound;
quinazolines;
secondary amino compound | autophagy inducer |
N-[4-(4-morpholinyl)phenyl]carbamic acid butyl ester
[no description available] | 2.15 | 1 | 0 | morpholines | |
4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
4-(4-chlorophenoxy)-1-(1-piperidinyl)-1-butanone
[no description available] | 2.15 | 1 | 0 | N-acylpiperidine | |
N-(3-phenylpropyl)methanesulfonamide
[no description available] | 2.15 | 1 | 0 | benzenes | |
4-acetamido-N-(2-methoxyethyl)benzamide
[no description available] | 2.15 | 1 | 0 | amidobenzoic acid | |
2-methyl-N-(2,3,4,5,6-pentafluorophenyl)-3-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine
[no description available] | 2.46 | 2 | 0 | aromatic ether | |
3,4-dihydro-2H-quinolin-1-yl-(4-propoxyphenyl)methanone
[no description available] | 2.15 | 1 | 0 | quinolines | |
5-bromo-N-(2-phenylphenyl)-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
2-[2-(4-chlorophenoxy)ethylthio]pyrimidine
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
3-(3-bromoanilino)-1-(5-methyl-2-furanyl)-1-propanone
[no description available] | 2.15 | 1 | 0 | aralkylamine | |
4-[2-(4-bromo-2-chlorophenoxy)-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester
[no description available] | 2.15 | 1 | 0 | piperazinecarboxylic acid | |
2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acid
[no description available] | 2.15 | 1 | 0 | benzamides | |
1-[2-(2-chlorophenoxy)ethoxy]-2-methoxy-4-methylbenzene
[no description available] | 2.15 | 1 | 0 | methoxybenzenes | |
N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | biphenyls | |
N-[2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-2-benzimidazol-3-iumyl]ethenyl]-N-methylaniline
[no description available] | 2.46 | 2 | 0 | benzimidazoles | |
5,6,7,8-tetrafluoro-2-(2,3,4,5,6-pentafluorophenyl)-4h-1-benzopyran-4-one
5,6,7,8-tetrafluoro-2-(2,3,4,5,6-pentafluorophenyl)-4H-1-benzopyran-4-one: structure in first source | 2.15 | 1 | 0 | | |
4-(1-adamantyl)-2-methyl-1,3-thiazole
[no description available] | 2.46 | 2 | 0 | thiazoles | |
2-[bis(5-methyl-2-furanyl)methyl]-6-nitrophenol
[no description available] | 2.15 | 1 | 0 | nitrophenol | |
2-amino-6-[4-(6-chloro-2-pyridinyl)-1-piperazinyl]pyridine-3,5-dicarbonitrile
[no description available] | 2.46 | 2 | 0 | piperazines;
pyridines | |
2-(4-nitrophenyl)-N-(2-oxolanylmethyl)-4-quinazolinamine
[no description available] | 2.15 | 1 | 0 | quinazolines | |
2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one
[no description available] | 2.15 | 1 | 0 | aromatic ketone | |
1-(4-fluorophenyl)-3-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)-3-pyrazolyl]urea
[no description available] | 2.46 | 2 | 0 | pyrazoles;
ring assembly | |
Methyl(2-furoylamino)acetic acid
[no description available] | 2.15 | 1 | 0 | N-acyl-amino acid | |
5-nitro-8-(1-pyrrolidinyl)quinoline
[no description available] | 2.15 | 1 | 0 | nitro compound;
quinolines | |
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamide
[no description available] | 2.15 | 1 | 0 | amino acid amide | |
2-[(4-methylphenyl)sulfonylamino]pentanoic acid
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
4,6-dimorpholino-n-(4-nitrophenyl)-1,3,5-triazin-2-amine
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine: an mTOR activator; structure in first source | 2.15 | 1 | 0 | | |
1-[(3-chlorophenyl)methyl]-N,N-diethyl-3-piperidinecarboxamide
[no description available] | 2.15 | 1 | 0 | piperidines | |
1-(2,6-dimethyl-1-piperidinyl)-2-phenylethanone
[no description available] | 2.15 | 1 | 0 | acetamides | |
2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile
[no description available] | 2.15 | 1 | 0 | methoxybenzenes | |
3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
4-(5,6-diphenyl-1,2,4-triazin-3-yl)morpholine
[no description available] | 2.15 | 1 | 0 | dialkylarylamine;
tertiary amino compound | |
(3,5-Dimethyl-1-adamantyl)amine nitrate
[no description available] | 2.15 | 1 | 0 | nitrates | |
1-(4-tert-butylphenoxy)-3-(1H-1,2,4-triazol-5-ylthio)-2-propanol
[no description available] | 2.15 | 1 | 0 | alkylbenzene | |
N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamine
[no description available] | 2.15 | 1 | 0 | N-alkylpyrrolidine | |
4-phenyl-N-(pyridin-4-ylmethyl)-2-butanamine
[no description available] | 2.15 | 1 | 0 | aralkylamine | |
N-(5-nitro-2-pyridinyl)cyclopropanecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
3-[(4-bromophenyl)methyl]-4-(4-methoxyanilino)-4-oxobutanoic acid
[no description available] | 2.15 | 1 | 0 | anilide | |
3-ethyl-N-(2H-tetrazol-5-yl)-1-adamantanecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
N-(4-propan-2-ylphenyl)-3-bicyclo[2.2.1]heptanecarboxamide
[no description available] | 2.15 | 1 | 0 | monoterpenoid | |
2-(4,6,7-Trimethyl-2-quinazolinyl)guanidine
[no description available] | 2.46 | 2 | 0 | quinazolines | |
4-chloro-N-[2-(4-nitroanilino)ethyl]benzamide
[no description available] | 2.15 | 1 | 0 | carbonyl compound;
organohalogen compound | |
polysulfide rubber
[no description available] | 2.46 | 2 | 0 | | |
2-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)-oxomethyl]-1-cyclohexanecarboxylic acid
[no description available] | 2.15 | 1 | 0 | benzodioxine | |
2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenol
[no description available] | 2.15 | 1 | 0 | aromatic compound | |
2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
1-ethoxy-3-(2-methoxy-4-prop-2-enylphenoxy)-2-propanol
[no description available] | 2.15 | 1 | 0 | methoxybenzenes | |
6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile
[no description available] | 2.15 | 1 | 0 | organochlorine compound;
pyranopyrazole | |
1-(2-chlorophenoxy)-3-(2-methyl-1-benzimidazolyl)-2-propanol
[no description available] | 2.15 | 1 | 0 | benzimidazoles | |
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide
[no description available] | 2.15 | 1 | 0 | hydroxyquinoline | |
N-(2-hydroxy-5-methylphenyl)-2-furancarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
furans | |
4-amino-7,8,9,10-tetrahydro-6H-pyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile
[no description available] | 2.15 | 1 | 0 | organic heterobicyclic compound;
organonitrogen heterocyclic compound | |
1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
6-[(3,4-difluoroanilino)-oxomethyl]-1-cyclohex-3-enecarboxylic acid
[no description available] | 2.15 | 1 | 0 | anilide | |
4-[(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)amino]-4-oxobutanoic acid
[no description available] | 2.15 | 1 | 0 | organosulfur heterocyclic compound | |
[3-methyl-4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-thiophen-2-ylmethanone
[no description available] | 2.15 | 1 | 0 | aromatic amide;
thiophenes | |
[4-(2-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanone
[no description available] | 2.15 | 1 | 0 | piperazines | |
N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
heteroarene | |
4-[2-nitro-5-[4-(phenylmethyl)sulfonyl-1-piperazinyl]phenyl]morpholine
[no description available] | 2.15 | 1 | 0 | piperazines | |
5-(4-ethylsulfonyl-1-piperazinyl)-2-nitro-N-(3-pyridinylmethyl)aniline
[no description available] | 2.15 | 1 | 0 | piperazines | |
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide
[no description available] | 2.15 | 1 | 0 | benzothiazoles | |
N-ethyl-N-[2-[(5-nitro-8-quinolinyl)amino]ethyl]benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | nitro compound;
quinolines | |
1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
3,4,5-trimethoxy-N-[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]benzamide
[no description available] | 2.15 | 1 | 0 | benzamides | |
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene
BRL-50481 : A C-nitro compound that is benzene substituted by N,N-dimethylaminosulfonyl, methyl and nitro groups at positions 1, 2 and 5, respectively. It is a phosphodiesterase inhibitor selective for the PDE7 subtype (Ki = 180 nM). | 2.15 | 1 | 0 | C-nitro compound;
sulfonamide;
toluenes | bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector |
6,3',4'-Trimethoxyflavanone
[no description available] | 2.15 | 1 | 0 | ether;
flavonoids | |
1-[4-(3-ethoxyphenoxy)butyl]imidazole
[no description available] | 2.15 | 1 | 0 | aromatic ether | |
5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole
[no description available] | 2.15 | 1 | 0 | oxadiazole;
ring assembly | |
2-[1-(3,4-dihydro-2H-quinolin-1-yl)-1-oxopropan-2-yl]isoindole-1,3-dione
[no description available] | 2.15 | 1 | 0 | phthalimides | |
[4-(benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide
[no description available] | 2.15 | 1 | 0 | amidobenzoic acid | |
6-[[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
2,5-dimethoxy-n-(quinolin-3-yl)benzenesulfonamide
2,5-dimethoxy-N-(quinolin-3-yl)benzenesulfonamide: a tissue-nonspecific alkaline phosphatase inhibitor; structure in first source | 2.15 | 1 | 0 | quinolines | |
LSM-25805
[no description available] | 2.15 | 1 | 0 | isoindoles | |
4-ethoxy-N-(3-quinolinyl)benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | quinolines | |
3-chloro-N-[3-(1-imidazolyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide
[no description available] | 2.15 | 1 | 0 | 1-benzothiophenes | |
lch-7749944
LCH-7749944: potent p21-activated kinase 4 inhibitor, structure in first source | 2.06 | 1 | 0 | | |
4-(4-nitrophenyl)-N-prop-2-enyl-1-piperazinecarbothioamide
[no description available] | 2.46 | 2 | 0 | piperazines | |
nsc 727447
NSC 727447: structure in first source | 2.15 | 1 | 0 | | |
quinine
[no description available] | 2.05 | 1 | 0 | cinchona alkaloid | antimalarial;
muscle relaxant;
non-narcotic analgesic |
zd 6474
CH 331: structure in first source | 2.46 | 2 | 0 | aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine | antineoplastic agent;
tyrosine kinase inhibitor |
2-methoxy-N-[(4-methylphenyl)methyl]-2-phenylacetamide
[no description available] | 2.15 | 1 | 0 | acetamides | |
2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide
[no description available] | 2.15 | 1 | 0 | C-nitro compound;
thiazoles | |
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine
[no description available] | 2.15 | 1 | 0 | methoxybenzenes | |
N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide
[no description available] | 2.15 | 1 | 0 | pyrrolidines | |
5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide
[no description available] | 2.46 | 2 | 0 | indoles | |
3,4-dimethoxy-N-[3-(methylthio)phenyl]benzenesulfonamide
[no description available] | 2.15 | 1 | 0 | sulfonamide | |
N-cyclohexyl-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide
[no description available] | 2.46 | 2 | 0 | aromatic amide;
heteroarene | |
3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamide
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
2-[(4-chlorophenyl)methylthio]-N-(2-hydroxy-5-nitrophenyl)acetamide
[no description available] | 2.15 | 1 | 0 | nitrophenol | |
2-(4-ethoxyphenyl)-N-[3-(1-imidazolyl)propyl]-4-quinolinecarboxamide
[no description available] | 2.15 | 1 | 0 | quinolines | |
2-[(3-ethyl-7-methyl-4-oxo-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide
[no description available] | 2.46 | 2 | 0 | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
N-(4-bromophenyl)-5-methyl-4-nitro-1H-pyrazol-3-amine
[no description available] | 2.15 | 1 | 0 | C-nitro compound | |
3,3-bis(4-hydroxyphenyl)-7-methyl-1,3-dihydro-2h-indol-2-one
3,3-bis(4-hydroxyphenyl)-7-methyl-1,3-dihydro-2H-indol-2-one: an estrogen receptor alpha inhibitor | 2.15 | 1 | 0 | | |
N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide | |
N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide
[no description available] | 2.15 | 1 | 0 | aromatic amide;
thiazoles | |
7-chloro-N-(phenylmethyl)-4-quinolinamine
[no description available] | 2.31 | 1 | 0 | aminoquinoline | |
ex 527
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide: structure in first source. 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide : A member of the class of carbazoles that is 2,3,4,9-tetrahydro-1H-carbazole which is substituted at position 1 by an aminocarbohyl group and at position 6 by a chlorine. | 2.15 | 1 | 0 | carbazoles;
monocarboxylic acid amide;
organochlorine compound | |
quercetin
[no description available] | 2.1 | 1 | 0 | 7-hydroxyflavonol;
pentahydroxyflavone | antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger |
linoleic acid
Linoleic Acid: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed). linoleic acid : An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry. | 3.51 | 1 | 0 | octadecadienoic acid;
omega-6 fatty acid | algal metabolite;
Daphnia galeata metabolite;
plant metabolite |
alprostadil
[no description available] | 3.51 | 1 | 0 | prostaglandins E | anticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent |
prostaglandin a1
[no description available] | 3.51 | 1 | 0 | prostaglandins A | |
pitavastatin
pitavastatin : A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise. | 3.51 | 1 | 0 | cyclopropanes;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
quinolines;
statin (synthetic) | antioxidant |
trichomonacid
trichomonacid: RN given refers to phosphate (1:3) salt | 2.46 | 2 | 0 | | |
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
[no description available] | 2.46 | 2 | 0 | triazolopyrimidines | |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-4-carboxamide
[no description available] | 2.46 | 2 | 0 | isoindoles | |
3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one
[no description available] | 2.15 | 1 | 0 | indoles | |
cgp 71683 a
[no description available] | 2.06 | 1 | 0 | naphthalenes;
sulfonic acid derivative | |
4-methyl-2,7-diphenyl-8H-pyrido[2,3-d]pyrimidin-5-one
[no description available] | 2.15 | 1 | 0 | phenylpyridine | |
3-methylharman
[no description available] | 2.15 | 1 | 0 | | |
2-(dimethylaminostyryl)-1-ethylpyridinium
2-(dimethylaminostyryl)-1-ethylpyridinium: fluorescent monitor for energetic state of isolated brown- adipose-tissue mitochondria; RN given refers to parent cpd; synonym DASPEI refers to iodide | 2.06 | 1 | 0 | pyridinium ion | |
1-methyl-beta-carboline-3-carboxylic acid
1-methyl-beta-carboline-3-carboxylic acid: metabolite from cows fed with corn silage; structure in first source | 2.15 | 1 | 0 | | |
penicillin v
[no description available] | 2.04 | 1 | 0 | 1,1'-diethyl-2,2'-cyanine;
quinolines | |
hydrocortisone acetate, (11beta)-isomer
[no description available] | 2.46 | 2 | 0 | | |
xib 4035
XIB 4035: a GFRalpha-1 agonist; structure in first source | 2.46 | 2 | 0 | | |
10-hydroxy-3-methyl-8-pentyl-2,4-dihydro-1H-[1]benzopyrano[3,4-c]pyridin-5-one
[no description available] | 2.46 | 2 | 0 | pyridochromene | |
lumefantrine
Lumefantrine: A fluorene derivative that is used in combination with ARTEMETHER for the treatment of MALARIA (see ARTEMETHER-LUMEFANTRINE DRUG COMBINATION).. lumefantrine : A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria. | 2.46 | 2 | 0 | fluorenes;
monochlorobenzenes;
secondary alcohol;
tertiary amine | antimalarial |
suloctidil
Suloctidil: A peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312) | 2.04 | 1 | 0 | | |
edatrexate
edatrexate: structure given in first source | 2.46 | 2 | 0 | glutamic acid derivative | |
mannich bases
Mannich Bases: Ketonic amines prepared from the condensation of a ketone with formaldehyde and ammonia or a primary or secondary amine. A Mannich base can act as the equivalent of an alpha,beta unsaturated ketone in synthesis or can be reduced to form physiologically active amino alcohols. | 7.08 | 1 | 0 | | |
cgp 71683 a
CGP 71683 A: selective NPY Y(5) receptor antagonist; structure in first source | 2.04 | 1 | 0 | | |
norketotifen
norketotifen: Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy; structure in first source | 2.06 | 1 | 0 | organosulfur heterocyclic compound | |
artenimol
artenimol: derivative of antimalarial drug artemisinin (quinghaosu) | 2.04 | 1 | 0 | | |
aee 788
AEE 788: structure in first source | 2.46 | 2 | 0 | 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist;
trypanocidal drug |
6-chlorotacrine
6-chlorotacrine: structure given in first source | 2.1 | 1 | 0 | | |
tomaymycin
tomaymycin: structure. tomaymycin : A pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine which is substituted at positions 2,5,7,8 and 11R by ethylidene, oxo, methoxy, hydroxy and methoxy groups, respectively. It is a natural product of Streptomyces achromogenes that binds covalently with guanine in the minor groove of DNA. It is an antitumoral compound which is active in ovarian, plasmacytoma, and leukemia cancer cell lines at nanomolar concentrations.. (Z)-tomaymycin : The (Z)-isomer of tomaymycin. | 2.46 | 2 | 0 | tomaymycin | |
amodiaquine hydrochloride
[no description available] | 2.45 | 2 | 0 | | |
gramicidin a
Gramicidin: A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN. | 2.46 | 2 | 0 | | |
N-methyl-3-[5-(3-phenylpropyl)-1,3,4-oxadiazol-2-yl]-N-(3-thiophenylmethyl)propanamide
[no description available] | 2.46 | 2 | 0 | benzenes | |
rs 39604
RS 39604 hydrochloride : A hydrochloride salt obtained by mixing equimolar amounts of RS 39604 with hydrochloric acid. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.. RS 39604 : An aromatic ether that is the 3,5-dimethoxybenzyl derivative of N-(2-{4-[3-(4-amino-5-chloro-2-hydroxyphenyl)-3-oxopropyl]piperidin-1-yl}ethyl)methanesulfonamide. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies. | 2.04 | 1 | 0 | hydrochloride | serotonergic antagonist |
chiniofon
Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses. | 1.96 | 1 | 0 | | |
heme
Heme: The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.. ferroheme : Any iron(II)--porphyrin coordination complex.. ferroheme b : Heme b in which the iron has oxidation state +2.. heme : A heme is any tetrapyrrolic chelate of iron. | 2.15 | 1 | 0 | | |
hypoxanthine
[no description available] | 2.1 | 1 | 0 | nucleobase analogue;
oxopurine;
purine nucleobase | fundamental metabolite |
inosinic acid
Inosine Monophosphate: Inosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. | 2.01 | 1 | 0 | inosine phosphate;
purine ribonucleoside 5'-monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite |
sildenafil
sildenafil : A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position. | 2.15 | 1 | 0 | piperazines;
pyrazolopyrimidine;
sulfonamide | EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent |
2-methyl-4(3h)-quinazolinone
2-methyl-4(3H)-quinazolinone: from Bacillus cereus; structure given in first source | 2.15 | 1 | 0 | | |
n(4)-desoxychlordiazepoxide
N(4)-desoxychlordiazepoxide: not phototoxic; structure given in first source | 2.15 | 1 | 0 | | |
1-[amino-[(6-methoxy-4-methyl-2-quinazolinyl)amino]methylidene]-3-phenylurea
[no description available] | 2.46 | 2 | 0 | quinazolines | |
2-amino-3-hydroxyphenazine
2-amino-3-hydroxyphenazine: structure given in first source | 2.15 | 1 | 0 | | |
2-styrylquinazolin-4(3h)-one
2-styrylquinazolin-4(3H)-one: structure given in first source | 2.15 | 1 | 0 | | |
2-amino-5-iodo-6-phenyl-4-pyrimidinone
[no description available] | 2.15 | 1 | 0 | | |
quininib
quininib: has antiangiogenic activity; structure in first source. quininib : A styrylquinoline that is trans-2-styrylquinoline in which the the phenyl group has been substituted at position 2 by a hydroxy group. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1. The major species at pH 7.3 | 2.15 | 1 | 0 | phenols;
styrylquinoline | angiogenesis inhibitor |
bropirimine
[no description available] | 2.15 | 1 | 0 | pyrimidines | |
2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-1H-quinazolin-4-one
[no description available] | 2.15 | 1 | 0 | quinazolines | |
2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-6-(methoxymethyl)-1H-pyrimidin-4-one
[no description available] | 2.15 | 1 | 0 | quinazolines | |