tazarotene has been researched along with Sensitivity and Specificity in 8 studies
tazarotene: a topical acetylenic retinoid; a topical kerytolytic
tazarotene : The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retinoids like tazarotene are approved for the treatment of chronic plaque psoriasis." | 5.10 | Instrumental evaluation of retinoid-induced skin irritation. ( Altmeyer, P; Hoffmann, M; Stücker, M, 2002) |
| " Tazarotene (AGN 190168), a retinoic acid receptor (RAR)-specific retinoid, is effective in the treatment of psoriasis, a hyperproliferative and inflammatory skin disease." | 3.69 | Negative regulation of two hyperproliferative keratinocyte differentiation markers by a retinoic acid receptor-specific retinoid: insight into the mechanism of retinoid action in psoriasis. ( Asano, AT; Chandraratna, RA; Duvic, M; Friant, S; Krasinski, G; Malhotra, M; Nagpal, S; Patel, S; Shafer, J; Teng, M; Thacher, SM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, YT | 1 |
| Hu, ZL | 1 |
| Shao, FX | 1 |
| Song, M | 1 |
| Hang, TJ | 1 |
| Tong, Y | 1 |
| Pan, H | 1 |
| Sun, C | 1 |
| Xin, X | 1 |
| Ding, L | 1 |
| Ma, P | 1 |
| Epstein, E | 1 |
| Greenspan, A | 1 |
| Loesche, C | 1 |
| Vendetti, N | 1 |
| Georgeian, K | 1 |
| Gilbert, R | 1 |
| Poncet, M | 1 |
| Baker, MD | 1 |
| Soto, P | 1 |
| Nagpal, S | 1 |
| Thacher, SM | 1 |
| Patel, S | 1 |
| Friant, S | 1 |
| Malhotra, M | 1 |
| Shafer, J | 1 |
| Krasinski, G | 1 |
| Asano, AT | 1 |
| Teng, M | 1 |
| Duvic, M | 1 |
| Chandraratna, RA | 1 |
| Fleischer, AB | 1 |
| Feldman, SR | 1 |
| Dekle, CL | 1 |
| Smith, KC | 1 |
| Lebwohl, M | 1 |
| Stücker, M | 1 |
| Hoffmann, M | 1 |
| Altmeyer, P | 1 |
1 review available for tazarotene and Sensitivity and Specificity
| Article | Year |
|---|---|
Topical antipsoriatics.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Anti-Inflammatory Agents; Calcitriol; D | 2000 |
3 trials available for tazarotene and Sensitivity and Specificity
| Article | Year |
|---|---|
Cumulative irritation comparison of adapalene gel and solution with 2 tazarotene gels and 3 tretinoin formulations.
Topics: Adapalene; Adult; Aged; Dermatologic Agents; Double-Blind Method; Drug Interactions; Erythema; Femal | 2003 |
The SAPASI is valid and responsive to psoriasis disease severity changes in a multi-center clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Dermatologic Agents; Double-Blind Method; Female; Follow-Up Studies; | 1999 |
Instrumental evaluation of retinoid-induced skin irritation.
Topics: Administration, Cutaneous; Adult; Calcitriol; Dose-Response Relationship, Drug; Drug Therapy, Combin | 2002 |
4 other studies available for tazarotene and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of tazarotene, clindamycin phosphate and their active metabolites in Bama mini-pig skin by LC-MS/MS: Application to the development of a tazarotene/clindamycin phosphate cream.
Topics: Animals; Chromatography, Liquid; Clindamycin; Female; Linear Models; Male; Nicotinic Acids; Reproduc | 2021 |
Simultaneous determination of tazarotene and its active metabolite tazarotenic acid in minipig plasma by LC-MS/MS and its application in pharmacokinetic study after topical administration of tazarotene gel.
Topics: Administration, Topical; Animals; Chromatography, Liquid; Female; Linear Models; Male; Nicotinic Aci | 2015 |
Questionable techniques for evaluating photodamage.
Topics: Administration, Topical; Humans; Nicotinic Acids; Ointments; Sensitivity and Specificity; Severity o | 2002 |
Negative regulation of two hyperproliferative keratinocyte differentiation markers by a retinoic acid receptor-specific retinoid: insight into the mechanism of retinoid action in psoriasis.
Topics: Antigens, Differentiation; Antineoplastic Agents; Biomarkers; Calcium-Binding Proteins; Calgranulin | 1996 |