phycoerythrobilin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

phycoerythrobilin: tetrapyrrole prosthetic group of phycoerythrin protein [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	193526
MeSH ID	M0057096

Synonyms (1)

Synonym
phycoerythrobilin

Research Excerpts

Overview

Phycoerythrobilin (PEB) is an open-chain tetrapyrrole derived from heme. PEB plays an important role as light-harvesting pigment in the phycobiliproteins of cyanobacteria and red algae.

Excerpt	Reference	Relevance
"Phycoerythrobilin (PEB) is an open-chain tetrapyrrole derived from heme and plays an important role as light-harvesting pigment in the phycobiliproteins of cyanobacteria and red algae. "	( Pink bacteria-Production of the pink chromophore phycoerythrobilin with Escherichia coli. Banek, A; Frankenberg-Dinkel, N; Geib, D; Ledermann, B; Sorg, M; Stiefelmaier, J; Ulber, R, 2018)	2.18
"PEB (phycoerythrobilin) is a pink-coloured open-chain tetrapyrrole molecule found in the cyanobacterial light-harvesting phycobilisome. "	( Radical mechanism of cyanophage phycoerythrobilin synthase (PebS). Busch, AW; Frankenberg-Dinkel, N; Hofmann, E; Lubitz, W; Reijerse, EJ, 2011)	1.17
"Phycoerythrobilin is a linear tetrapyrrole molecule found in cyanobacteria, red algae, and cryptomonads. "	( Insights into phycoerythrobilin biosynthesis point toward metabolic channeling. Dammeyer, T; Frankenberg-Dinkel, N, 2006)	2.14

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (63)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (7.94)	18.7374
1990's	5 (7.94)	18.2507
2000's	21 (33.33)	29.6817
2010's	27 (42.86)	24.3611
2020's	5 (7.94)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.95

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	27.95 (24.57)
Research Supply Index	4.16 (2.92)
Research Growth Index	4.92 (4.65)
Search Engine Demand Index	34.37 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (27.95)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (1.59%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	62 (98.41%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
iodoacetamide [no description available]	2.01	1
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	4.34	20	pyrrole; secondary amine
glycofurol [no description available]	2.02	1
15,16-dihydrobiliverdin ixa 15,16-dihydrobiliverdin IXa: partially reduced intermediate in the formation of phycobilins for biliverdin IXa; structure given in first source	2.76	3	biladienes
biliverdine [no description available]	3.74	10
phycocyanobilin phycocyanobilin: tetrapyrrole prosthetic group of phycocyanin protein. phycocyanobilin : A bilin that consists of 8,12-bis(2-carboxyethyl)-18-ethyl-3-ethylidene-2,7,13,17-tetramethyl-2,3-dihydrobilin bearing two oxo substituents at positions 1 and 19.	4.14	16
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.	2.8	3	cysteinium	fundamental metabolite
urobilin [no description available]	3.98	13
ammonium sulfate Ammonium Sulfate: Sulfuric acid diammonium salt. It is used in CHEMICAL FRACTIONATION of proteins.. ammonium sulfate : An inorganic sulfate salt obtained by reaction of sulfuric acid with two equivalents of ammonia. A high-melting (decomposes above 280degreeC) white solid which is very soluble in water (70.6 g/100 g water at 0degreeC; 103.8 g/100 g water at 100degreeC), it is widely used as a fertilizer for alkaline soils.	2.11	1	ammonium salt; inorganic sulfate salt	fertilizer
tetrodotoxin Tetrodotoxin: An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.. tetrodotoxin : A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.	3.16	1	azatetracycloalkane; oxatetracycloalkane; quinazoline alkaloid	animal metabolite; bacterial metabolite; marine metabolite; neurotoxin; voltage-gated sodium channel blocker
chlorophyll chlorophyll a': RN refers to (SP-4-2-(3S-(3alpha(2E,7S,11S),4beta,21alpha)))-isomer	2.13	1
chlorophyll a Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.	2.13	1	chlorophyll; methyl ester	cofactor
silanediol silanediol: structure in first source	2.25	1	silicon hydroxide
phytochromobilin phytochromobilin: structure given in first source; this bilin is a pigment derived from phycoerythrobilin-containing proteins. phytochromobilin : A member of the class of bilins which functions as the chromophore of light-sensing phytochromes in plants.. (3Z)-phytochromobilin(2-) : Dicarboxylate anion of (3Z)-phytochromobilin.	7.91	4
saxitoxin Saxitoxin: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.. saxitoxin : An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning.	3.16	1	alkaloid; carbamate ester; guanidines; ketone hydrate; paralytic shellfish toxin; pyrrolopurine	cyanotoxin; marine metabolite; neurotoxin; sodium channel blocker; toxin
pheophytin a pheophytin a: structure given in first source; RN given refers to (3S-(3alpha(2E,7S,11S),4beta,21beta))-isomer	2.13	1
phycoviolobilin phycoviolobilin: structure in first source	2.46	2

Condition	Indicated	Relationship Strength	Studies	Trials
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	2.02	1	0

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