Adenosine deaminase-like protein

An adenosine deaminase-like protein that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q6DHV7]

EC 3.5.4.-;
Adenosine deaminase-like protein isoform 1;
N6-mAMP deaminase;
HsMAPDA;
N6-methyl-AMP aminohydrolase

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
adenosine monophosphate	Homo sapiens (human)	Km	32.8000	1	1
o(6)-methyldeoxyguanylic acid	Homo sapiens (human)	Km	6.0000	1	1

This protein enables 3 target(s):

Target	Category	Definition
metal ion binding	molecular function	Binding to a metal ion. [GOC:ai]
N6-methyl-AMP deaminase activity	molecular function	Catalysis of the reaction: H+ + H2O + N6-methyl-AMP = IMP + methylamine. Can also use N6-methyl-dAMP as a substrate. [PMID:29884623, RHEA:16001]
adenosine deaminase activity	molecular function	Catalysis of the reaction: adenosine + H2O = inosine + NH3. [EC:3.5.4.4]

This protein is located in 1 target(s):

Target	Category	Definition
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]

This protein is involved in 3 target(s):

Target	Category	Definition
nucleotide metabolic process	biological process	The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). [GOC:ma]
inosine biosynthetic process	biological process	The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. [GOC:go_curators]
adenosine catabolic process	biological process	The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. [GOC:go_curators]