Compounds > 2-chloroadenosine
Page last updated: 2024-09-21

2-chloroadenosine

Description

5-chloroformycin A: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8974
CHEMBL ID285819
CHEBI ID125640
SCHEMBL ID104094
MeSH IDM0024149

Synonyms (72)

Synonym
brn 0043957
2-chloroadenosinehemihydrate
einecs 205-678-3
nsc 36896
MLS002153284
gtpl372
cado
2cl-ado
REGID_FOR_CID_8974
MLS000028365 ,
smr000058612
146-77-0
2-chloroadenosine ,
adenosine, 2-chloro-
PDSP1_000569
(2r,3r,4s,5r)-2-(6-amino-2-chloro-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
PDSP2_000983
PDSP1_001209
PDSP2_000567
PDSP2_001193
2 chloroadenosine
NCGC00021540-05
PDSP1_000999
NCGC00021540-04
NCGC00021540-03
CHEBI:125640
HMS2051B22
2-cado
NCGC00021540-06
CHEMBL285819 ,
(2r,3r,4s,5r)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
6-amino-2-chloropurine riboside
bdbm50009525
2-[6-amino-2-(2-cyclopentyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2-ci adenosine
2-chloroado
MLS001424176
81012-94-4
HMS2235K11
AKOS015995296
c10h12cln5o4
CCG-101063
103090-47-7
5-chloroformycin a
4-26-00-03725 (beilstein handbook reference)
7w7zug45g8 ,
unii-7w7zug45g8
AKOS015896917
2-chloro adenosine
SCHEMBL104094
NC00313
AM83941
2-chloro-adenosine
2-chloro-9-(beta-d-ribofuranosyl)adenine
(2r,3r,4s,5r)-2-(6-amino-2-chloro-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2-chloroadenosine (cado)
HB2844
(2r,3r,4s,5r)-2-(6-amino-2-chloro-9h-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
OPERA_ID_460
CS-W008344
(2r,3r,4s,5r)-2-(6-amino-2-chloro-9h-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
EN300-181910
2-chloro[3h]adenosine
Q27071883
AS-12085
DTXSID301017134
AMY2581
NCGC00021540-11
HY-W008344
adenosine, 2-chloro-; 2-chloroadenosine; 2-chloro-d-adenosine; antibiotic at 265b; cado; nsc 36896
PD003180
Z1741982920

Drug Classes (1)

ClassDescription
purine nucleoside
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (47)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency18.31740.003245.467312,589.2998AID2517
Chain A, Beta-lactamaseEscherichia coli K-12Potency70.79460.044717.8581100.0000AID485294
glp-1 receptor, partialHomo sapiens (human)Potency4.99440.01846.806014.1254AID624148; AID624172
TDP1 proteinHomo sapiens (human)Potency2.95580.000811.382244.6684AID686978; AID686979
Smad3Homo sapiens (human)Potency22.38720.00527.809829.0929AID588855
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency6.30960.00137.762544.6684AID914; AID915
67.9K proteinVaccinia virusPotency20.32170.00018.4406100.0000AID720579; AID720580
IDH1Homo sapiens (human)Potency18.35640.005210.865235.4813AID686970
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency17.90080.316212.443531.6228AID902; AID924
vasopressin V1b receptorHomo sapiens (human)Potency19.43840.194416.018043.6206AID492948
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency20.59620.00419.984825.9290AID504444
mitogen-activated protein kinase 1Homo sapiens (human)Potency12.06270.039816.784239.8107AID1454; AID995
flap endonuclease 1Homo sapiens (human)Potency8.43680.133725.412989.1251AID588795
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency25.11890.050127.073689.1251AID588590
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency4.46680.15855.287912.5893AID540303
plasminogen precursorMus musculus (house mouse)Potency4.46680.15855.287912.5893AID540303
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency4.46680.15855.287912.5893AID540303
gemininHomo sapiens (human)Potency29.09290.004611.374133.4983AID624296
survival motor neuron protein isoform dHomo sapiens (human)Potency35.48130.125912.234435.4813AID1458
relaxin receptor 1 isoform 1Homo sapiens (human)Potency9.32410.038814.350143.6206AID2676; AID489012; AID492949
relaxin receptor 2 isoform 1Homo sapiens (human)Potency17.32450.048815.980148.9431AID489043
lamin isoform A-delta10Homo sapiens (human)Potency22.74070.891312.067628.1838AID1487
Integrin beta-3Homo sapiens (human)Potency19.95260.316211.415731.6228AID924
Integrin alpha-IIbHomo sapiens (human)Potency19.95260.316211.415731.6228AID924
Ataxin-2Homo sapiens (human)Potency28.18380.011912.222168.7989AID588378
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
high affinity choline transporter 1 isoform aHomo sapiens (human)IC50 (µMol)0.53770.00036.210228.8403AID504840; AID588401
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)IC50 (µMol)10.00000.00001.77679.2000AID1368375
ReninHomo sapiens (human)Ki0.01000.00001.80787.4000AID195542
Heat shock protein HSP 90-alphaHomo sapiens (human)IC50 (µMol)1,250.00000.00040.695010.0000AID1452134
Heat shock protein HSP 90-alphaHomo sapiens (human)Ki2.20000.00020.54152.7000AID1694547
Adenosine receptor A3Homo sapiens (human)Ki3.08900.00000.930610.0000AID1138018; AID34574; AID34581; AID34704
EndoplasminHomo sapiens (human)Ki1.80000.00401.32057.0000AID1694546
Adenosine receptor A1Rattus norvegicus (Norway rat)IC50 (µMol)0.03700.00020.552110.0000AID31410
Adenosine receptor A1Rattus norvegicus (Norway rat)Ki0.13910.00011.20929.9700AID195542; AID195543; AID196738; AID31850; AID32177; AID32180; AID32503
Adenosine receptor A1Bos taurus (cattle)Ki0.02020.00000.71316.0000AID32002
5-hydroxytryptamine receptor 2AHomo sapiens (human)Ki10.00000.00000.385510.0000AID1324516
Adenosine receptor A3Rattus norvegicus (Norway rat)Ki0.94380.00030.91969.0000AID195542; AID195543; AID196738; AID33337; AID33485
Adenosine receptor A2aHomo sapiens (human)Ki0.15000.00001.06099.7920AID1138011; AID33928
Adenosine receptor A2bHomo sapiens (human)Ki23.45000.00021.635210.0000AID372151; AID372174
Adenosine receptor A2bRattus norvegicus (Norway rat)IC50 (µMol)0.16000.00240.68169.0000AID33405
Adenosine receptor A2bRattus norvegicus (Norway rat)Ki0.18800.00061.353610.0000AID195542; AID195543; AID196738; AID33590; AID33733
Adenosine receptor A1Homo sapiens (human)Ki0.00750.00020.931610.0000AID1138015; AID1324468; AID337880
Adenosine receptor A2aRattus norvegicus (Norway rat)IC50 (µMol)0.16000.00120.48289.0000AID33405
Adenosine receptor A2aRattus norvegicus (Norway rat)Ki0.15840.00021.494010.0000AID195542; AID195543; AID196738; AID32872; AID33590; AID33733; AID33939
Adenosine deaminase Bos taurus (cattle)Ki54.50000.00000.48937.0000AID554262
Adenylate cyclase type 5Rattus norvegicus (Norway rat)Ki0.08700.00140.04950.1180AID34574
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
NPYLR7BAedes aegypti (yellow fever mosquito)EC50 (µMol)1.15000.03902.289918.3000AID1259426
glycogen synthase kinase-3 beta isoform 1Homo sapiens (human)EC50 (µMol)300.00000.212522.156283.9400AID434954
Heat shock protein HSP 90-alphaHomo sapiens (human)Kd38.00000.00030.94889.8000AID1694547
Adenosine receptor A3Homo sapiens (human)EC50 (µMol)1.63000.00010.42587.9800AID34265
EndoplasminHomo sapiens (human)Kd8.60000.20001.93908.6000AID1694546
Adenosine receptor A2aHomo sapiens (human)EC50 (µMol)0.02510.00030.708110.0000AID30507
Adenosine receptor A2bHomo sapiens (human)EC50 (µMol)0.02510.00030.946110.0000AID30507
Adenosine receptor A2aCavia porcellus (domestic guinea pig)EC50 (µMol)8.00008.00008.00008.0000AID30510
Adenosine receptor A1Cavia porcellus (domestic guinea pig)EC50 (µMol)0.19050.01261.93385.6234AID32148
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Adenosine receptor A1Rattus norvegicus (Norway rat)EC25 (µMol)0.01300.00300.01420.0350AID175310
Adenosine receptor A2aHomo sapiens (human)Affinity constant5.00000.20006.028610.0000AID33910
Adenosine receptor A2bHomo sapiens (human)Affinity constant5.00000.20006.028610.0000AID33910
Adenosine receptor A2bRattus norvegicus (Norway rat)EC25 (µMol)0.01300.00300.01420.0350AID175310
Adenosine receptor A2bRattus norvegicus (Norway rat)Ratio0.06300.00330.82929.6000AID33746
Adenosine receptor A1Homo sapiens (human)Affinity constant0.01000.00301.069110.0000AID30353
Adenosine receptor A2aRattus norvegicus (Norway rat)EC25 (µMol)0.01300.00300.01420.0350AID175310
Adenosine receptor A2aRattus norvegicus (Norway rat)Ratio0.06300.00330.82309.6000AID33746
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (299)

Processvia Protein(s)Taxonomy
heart valve developmentcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
ventricular septum developmentcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
aorta developmentcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
negative regulation of transcription by RNA polymerase IIcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathwaycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
regulation of cGMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cAMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cGMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to macrophage colony-stimulating factor stimuluscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
negative regulation of vascular permeabilitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
positive regulation of vascular permeabilitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
regulation of cAMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cGMP catabolic processcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
positive regulation of inflammatory responsecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
establishment of endothelial barriercGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to mechanical stimuluscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to cAMPcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to cGMPcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to transforming growth factor beta stimuluscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathwaycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cellular response to 2,3,7,8-tetrachlorodibenzodioxinecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
positive regulation of gene expressioncGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
negative regulation of cGMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
negative regulation of cAMP-mediated signalingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
regulation of mitochondrion organizationcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
kidney developmentReninHomo sapiens (human)
mesonephros developmentReninHomo sapiens (human)
angiotensin maturationReninHomo sapiens (human)
renin-angiotensin regulation of aldosterone productionReninHomo sapiens (human)
proteolysisReninHomo sapiens (human)
regulation of blood pressureReninHomo sapiens (human)
male gonad developmentReninHomo sapiens (human)
hormone-mediated signaling pathwayReninHomo sapiens (human)
response to lipopolysaccharideReninHomo sapiens (human)
response to immobilization stressReninHomo sapiens (human)
drinking behaviorReninHomo sapiens (human)
regulation of MAPK cascadeReninHomo sapiens (human)
cell maturationReninHomo sapiens (human)
amyloid-beta metabolic processReninHomo sapiens (human)
response to cAMPReninHomo sapiens (human)
response to cGMPReninHomo sapiens (human)
cellular response to xenobiotic stimulusReninHomo sapiens (human)
juxtaglomerular apparatus developmentReninHomo sapiens (human)
negative regulation of low-density lipoprotein receptor activityIntegrin beta-3Homo sapiens (human)
positive regulation of protein phosphorylationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
cell-substrate junction assemblyIntegrin beta-3Homo sapiens (human)
cell adhesionIntegrin beta-3Homo sapiens (human)
cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
integrin-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
embryo implantationIntegrin beta-3Homo sapiens (human)
blood coagulationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of gene expressionIntegrin beta-3Homo sapiens (human)
negative regulation of macrophage derived foam cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast migrationIntegrin beta-3Homo sapiens (human)
negative regulation of lipid storageIntegrin beta-3Homo sapiens (human)
response to activityIntegrin beta-3Homo sapiens (human)
smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
platelet activationIntegrin beta-3Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
cell-substrate adhesionIntegrin beta-3Homo sapiens (human)
activation of protein kinase activityIntegrin beta-3Homo sapiens (human)
negative regulation of lipid transportIntegrin beta-3Homo sapiens (human)
regulation of protein localizationIntegrin beta-3Homo sapiens (human)
regulation of actin cytoskeleton organizationIntegrin beta-3Homo sapiens (human)
cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of osteoblast proliferationIntegrin beta-3Homo sapiens (human)
heterotypic cell-cell adhesionIntegrin beta-3Homo sapiens (human)
substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
tube developmentIntegrin beta-3Homo sapiens (human)
wound healing, spreading of epidermal cellsIntegrin beta-3Homo sapiens (human)
cellular response to platelet-derived growth factor stimulusIntegrin beta-3Homo sapiens (human)
apolipoprotein A-I-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
wound healingIntegrin beta-3Homo sapiens (human)
apoptotic cell clearanceIntegrin beta-3Homo sapiens (human)
regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
positive regulation of angiogenesisIntegrin beta-3Homo sapiens (human)
positive regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
symbiont entry into host cellIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast proliferationIntegrin beta-3Homo sapiens (human)
mesodermal cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationIntegrin beta-3Homo sapiens (human)
negative regulation of lipoprotein metabolic processIntegrin beta-3Homo sapiens (human)
negative chemotaxisIntegrin beta-3Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosolIntegrin beta-3Homo sapiens (human)
regulation of serotonin uptakeIntegrin beta-3Homo sapiens (human)
angiogenesis involved in wound healingIntegrin beta-3Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascadeIntegrin beta-3Homo sapiens (human)
platelet aggregationIntegrin beta-3Homo sapiens (human)
cellular response to mechanical stimulusIntegrin beta-3Homo sapiens (human)
cellular response to xenobiotic stimulusIntegrin beta-3Homo sapiens (human)
positive regulation of glomerular mesangial cell proliferationIntegrin beta-3Homo sapiens (human)
blood coagulation, fibrin clot formationIntegrin beta-3Homo sapiens (human)
maintenance of postsynaptic specialization structureIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor internalizationIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor diffusion trappingIntegrin beta-3Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
regulation of trophoblast cell migrationIntegrin beta-3Homo sapiens (human)
regulation of extracellular matrix organizationIntegrin beta-3Homo sapiens (human)
cellular response to insulin-like growth factor stimulusIntegrin beta-3Homo sapiens (human)
negative regulation of endothelial cell apoptotic processIntegrin beta-3Homo sapiens (human)
positive regulation of T cell migrationIntegrin beta-3Homo sapiens (human)
cell migrationIntegrin beta-3Homo sapiens (human)
telomere maintenance via telomeraseHeat shock protein HSP 90-alphaHomo sapiens (human)
neuron migrationHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of protein phosphorylationHeat shock protein HSP 90-alphaHomo sapiens (human)
activation of innate immune responseHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of defense response to virus by hostHeat shock protein HSP 90-alphaHomo sapiens (human)
skeletal muscle contractionHeat shock protein HSP 90-alphaHomo sapiens (human)
mitochondrial transportHeat shock protein HSP 90-alphaHomo sapiens (human)
response to unfolded proteinHeat shock protein HSP 90-alphaHomo sapiens (human)
response to heatHeat shock protein HSP 90-alphaHomo sapiens (human)
response to coldHeat shock protein HSP 90-alphaHomo sapiens (human)
response to xenobiotic stimulusHeat shock protein HSP 90-alphaHomo sapiens (human)
response to salt stressHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of lamellipodium assemblyHeat shock protein HSP 90-alphaHomo sapiens (human)
cardiac muscle cell apoptotic processHeat shock protein HSP 90-alphaHomo sapiens (human)
regulation of protein ubiquitinationHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of protein polymerizationHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of interferon-beta productionHeat shock protein HSP 90-alphaHomo sapiens (human)
regulation of protein localizationHeat shock protein HSP 90-alphaHomo sapiens (human)
protein refoldingHeat shock protein HSP 90-alphaHomo sapiens (human)
response to cocaineHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of protein import into nucleusHeat shock protein HSP 90-alphaHomo sapiens (human)
regulation of apoptotic processHeat shock protein HSP 90-alphaHomo sapiens (human)
regulation of protein-containing complex assemblyHeat shock protein HSP 90-alphaHomo sapiens (human)
protein unfoldingHeat shock protein HSP 90-alphaHomo sapiens (human)
response to estrogenHeat shock protein HSP 90-alphaHomo sapiens (human)
protein insertion into mitochondrial outer membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of nitric oxide biosynthetic processHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of protein catabolic processHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of cell sizeHeat shock protein HSP 90-alphaHomo sapiens (human)
response to antibioticHeat shock protein HSP 90-alphaHomo sapiens (human)
protein stabilizationHeat shock protein HSP 90-alphaHomo sapiens (human)
chaperone-mediated protein complex assemblyHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of cardiac muscle contractionHeat shock protein HSP 90-alphaHomo sapiens (human)
chaperone-mediated autophagyHeat shock protein HSP 90-alphaHomo sapiens (human)
cellular response to virusHeat shock protein HSP 90-alphaHomo sapiens (human)
regulation of postsynaptic membrane neurotransmitter receptor levelsHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of tau-protein kinase activityHeat shock protein HSP 90-alphaHomo sapiens (human)
telomerase holoenzyme complex assemblyHeat shock protein HSP 90-alphaHomo sapiens (human)
cellular response to heatHeat shock protein HSP 90-alphaHomo sapiens (human)
protein foldingHeat shock protein HSP 90-alphaHomo sapiens (human)
positive regulation of leukocyte migrationIntegrin alpha-IIbHomo sapiens (human)
cell-matrix adhesionIntegrin alpha-IIbHomo sapiens (human)
integrin-mediated signaling pathwayIntegrin alpha-IIbHomo sapiens (human)
angiogenesisIntegrin alpha-IIbHomo sapiens (human)
cell-cell adhesionIntegrin alpha-IIbHomo sapiens (human)
cell adhesion mediated by integrinIntegrin alpha-IIbHomo sapiens (human)
inflammatory responseAdenosine receptor A3Homo sapiens (human)
signal transductionAdenosine receptor A3Homo sapiens (human)
activation of adenylate cyclase activityAdenosine receptor A3Homo sapiens (human)
regulation of heart contractionAdenosine receptor A3Homo sapiens (human)
negative regulation of cell population proliferationAdenosine receptor A3Homo sapiens (human)
response to woundingAdenosine receptor A3Homo sapiens (human)
regulation of norepinephrine secretionAdenosine receptor A3Homo sapiens (human)
negative regulation of cell migrationAdenosine receptor A3Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activityAdenosine receptor A3Homo sapiens (human)
presynaptic modulation of chemical synaptic transmissionAdenosine receptor A3Homo sapiens (human)
G protein-coupled adenosine receptor signaling pathwayAdenosine receptor A3Homo sapiens (human)
actin rod assemblyEndoplasminHomo sapiens (human)
regulation of phosphoprotein phosphatase activityEndoplasminHomo sapiens (human)
cellular response to ATPEndoplasminHomo sapiens (human)
response to hypoxiaEndoplasminHomo sapiens (human)
protein transportEndoplasminHomo sapiens (human)
retrograde protein transport, ER to cytosolEndoplasminHomo sapiens (human)
protein folding in endoplasmic reticulumEndoplasminHomo sapiens (human)
response to endoplasmic reticulum stressEndoplasminHomo sapiens (human)
ERAD pathwayEndoplasminHomo sapiens (human)
negative regulation of apoptotic processEndoplasminHomo sapiens (human)
sequestering of calcium ionEndoplasminHomo sapiens (human)
cellular response to manganese ionEndoplasminHomo sapiens (human)
protein foldingEndoplasminHomo sapiens (human)
G protein-coupled adenosine receptor signaling pathwayAdenosine receptor A1Bos taurus (cattle)
response to purine-containing compoundAdenosine receptor A1Bos taurus (cattle)
temperature homeostasis5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of cytokine production involved in immune response5-hydroxytryptamine receptor 2AHomo sapiens (human)
glycolytic process5-hydroxytryptamine receptor 2AHomo sapiens (human)
intracellular calcium ion homeostasis5-hydroxytryptamine receptor 2AHomo sapiens (human)
activation of phospholipase C activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of cytosolic calcium ion concentration5-hydroxytryptamine receptor 2AHomo sapiens (human)
memory5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of cell population proliferation5-hydroxytryptamine receptor 2AHomo sapiens (human)
response to xenobiotic stimulus5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of phosphatidylinositol biosynthetic process5-hydroxytryptamine receptor 2AHomo sapiens (human)
regulation of dopamine secretion5-hydroxytryptamine receptor 2AHomo sapiens (human)
artery smooth muscle contraction5-hydroxytryptamine receptor 2AHomo sapiens (human)
urinary bladder smooth muscle contraction5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of heat generation5-hydroxytryptamine receptor 2AHomo sapiens (human)
negative regulation of potassium ion transport5-hydroxytryptamine receptor 2AHomo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of neuron apoptotic process5-hydroxytryptamine receptor 2AHomo sapiens (human)
protein localization to cytoskeleton5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of fat cell differentiation5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of glycolytic process5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of vasoconstriction5-hydroxytryptamine receptor 2AHomo sapiens (human)
symbiont entry into host cell5-hydroxytryptamine receptor 2AHomo sapiens (human)
sensitization5-hydroxytryptamine receptor 2AHomo sapiens (human)
behavioral response to cocaine5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of inflammatory response5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation5-hydroxytryptamine receptor 2AHomo sapiens (human)
detection of temperature stimulus involved in sensory perception of pain5-hydroxytryptamine receptor 2AHomo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain5-hydroxytryptamine receptor 2AHomo sapiens (human)
release of sequestered calcium ion into cytosol5-hydroxytryptamine receptor 2AHomo sapiens (human)
negative regulation of synaptic transmission, glutamatergic5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of ERK1 and ERK2 cascade5-hydroxytryptamine receptor 2AHomo sapiens (human)
G protein-coupled serotonin receptor signaling pathway5-hydroxytryptamine receptor 2AHomo sapiens (human)
presynaptic modulation of chemical synaptic transmission5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of execution phase of apoptosis5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of platelet aggregation5-hydroxytryptamine receptor 2AHomo sapiens (human)
positive regulation of DNA biosynthetic process5-hydroxytryptamine receptor 2AHomo sapiens (human)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger5-hydroxytryptamine receptor 2AHomo sapiens (human)
phospholipase C-activating serotonin receptor signaling pathway5-hydroxytryptamine receptor 2AHomo sapiens (human)
serotonin receptor signaling pathway5-hydroxytryptamine receptor 2AHomo sapiens (human)
chemical synaptic transmission5-hydroxytryptamine receptor 2AHomo sapiens (human)
synaptic transmission, dopaminergicAdenosine receptor A2aHomo sapiens (human)
response to amphetamineAdenosine receptor A2aHomo sapiens (human)
regulation of DNA-templated transcriptionAdenosine receptor A2aHomo sapiens (human)
phagocytosisAdenosine receptor A2aHomo sapiens (human)
apoptotic processAdenosine receptor A2aHomo sapiens (human)
inflammatory responseAdenosine receptor A2aHomo sapiens (human)
cellular defense responseAdenosine receptor A2aHomo sapiens (human)
adenylate cyclase-modulating G protein-coupled receptor signaling pathwayAdenosine receptor A2aHomo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathwayAdenosine receptor A2aHomo sapiens (human)
protein kinase C-activating G protein-coupled receptor signaling pathwayAdenosine receptor A2aHomo sapiens (human)
cell-cell signalingAdenosine receptor A2aHomo sapiens (human)
synaptic transmission, cholinergicAdenosine receptor A2aHomo sapiens (human)
central nervous system developmentAdenosine receptor A2aHomo sapiens (human)
blood coagulationAdenosine receptor A2aHomo sapiens (human)
sensory perceptionAdenosine receptor A2aHomo sapiens (human)
locomotory behaviorAdenosine receptor A2aHomo sapiens (human)
blood circulationAdenosine receptor A2aHomo sapiens (human)
negative regulation of cell population proliferationAdenosine receptor A2aHomo sapiens (human)
response to xenobiotic stimulusAdenosine receptor A2aHomo sapiens (human)
response to inorganic substanceAdenosine receptor A2aHomo sapiens (human)
positive regulation of glutamate secretionAdenosine receptor A2aHomo sapiens (human)
positive regulation of acetylcholine secretion, neurotransmissionAdenosine receptor A2aHomo sapiens (human)
regulation of norepinephrine secretionAdenosine receptor A2aHomo sapiens (human)
response to purine-containing compoundAdenosine receptor A2aHomo sapiens (human)
response to caffeineAdenosine receptor A2aHomo sapiens (human)
positive regulation of synaptic transmission, GABAergicAdenosine receptor A2aHomo sapiens (human)
synaptic transmission, glutamatergicAdenosine receptor A2aHomo sapiens (human)
positive regulation of urine volumeAdenosine receptor A2aHomo sapiens (human)
vasodilationAdenosine receptor A2aHomo sapiens (human)
eating behaviorAdenosine receptor A2aHomo sapiens (human)
negative regulation of vascular permeabilityAdenosine receptor A2aHomo sapiens (human)
negative regulation of neuron apoptotic processAdenosine receptor A2aHomo sapiens (human)
positive regulation of circadian sleep/wake cycle, sleepAdenosine receptor A2aHomo sapiens (human)
negative regulation of alpha-beta T cell activationAdenosine receptor A2aHomo sapiens (human)
astrocyte activationAdenosine receptor A2aHomo sapiens (human)
neuron projection morphogenesisAdenosine receptor A2aHomo sapiens (human)
positive regulation of protein secretionAdenosine receptor A2aHomo sapiens (human)
negative regulation of inflammatory responseAdenosine receptor A2aHomo sapiens (human)
regulation of mitochondrial membrane potentialAdenosine receptor A2aHomo sapiens (human)
membrane depolarizationAdenosine receptor A2aHomo sapiens (human)
regulation of calcium ion transportAdenosine receptor A2aHomo sapiens (human)
positive regulation of synaptic transmission, glutamatergicAdenosine receptor A2aHomo sapiens (human)
excitatory postsynaptic potentialAdenosine receptor A2aHomo sapiens (human)
inhibitory postsynaptic potentialAdenosine receptor A2aHomo sapiens (human)
prepulse inhibitionAdenosine receptor A2aHomo sapiens (human)
apoptotic signaling pathwayAdenosine receptor A2aHomo sapiens (human)
presynaptic modulation of chemical synaptic transmissionAdenosine receptor A2aHomo sapiens (human)
positive regulation of long-term synaptic potentiationAdenosine receptor A2aHomo sapiens (human)
positive regulation of apoptotic signaling pathwayAdenosine receptor A2aHomo sapiens (human)
G protein-coupled adenosine receptor signaling pathwayAdenosine receptor A2aHomo sapiens (human)
G protein-coupled adenosine receptor signaling pathwayAdenosine receptor A2bHomo sapiens (human)
positive regulation of chronic inflammatory response to non-antigenic stimulusAdenosine receptor A2bHomo sapiens (human)
G protein-coupled receptor signaling pathwayAdenosine receptor A2bHomo sapiens (human)
activation of adenylate cyclase activityAdenosine receptor A2bHomo sapiens (human)
positive regulation of vascular endothelial growth factor productionAdenosine receptor A2bHomo sapiens (human)
positive regulation of cGMP-mediated signalingAdenosine receptor A2bHomo sapiens (human)
cGMP-mediated signalingAdenosine receptor A2bHomo sapiens (human)
positive regulation of chemokine productionAdenosine receptor A2bHomo sapiens (human)
positive regulation of interleukin-6 productionAdenosine receptor A2bHomo sapiens (human)
mast cell degranulationAdenosine receptor A2bHomo sapiens (human)
positive regulation of mast cell degranulationAdenosine receptor A2bHomo sapiens (human)
relaxation of vascular associated smooth muscleAdenosine receptor A2bHomo sapiens (human)
presynaptic modulation of chemical synaptic transmissionAdenosine receptor A2bHomo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathwayAdenosine receptor A2bHomo sapiens (human)
vasodilationAdenosine receptor A2bHomo sapiens (human)
temperature homeostasisAdenosine receptor A1Homo sapiens (human)
response to hypoxiaAdenosine receptor A1Homo sapiens (human)
G protein-coupled adenosine receptor signaling pathwayAdenosine receptor A1Homo sapiens (human)
regulation of respiratory gaseous exchange by nervous system processAdenosine receptor A1Homo sapiens (human)
negative regulation of acute inflammatory responseAdenosine receptor A1Homo sapiens (human)
negative regulation of leukocyte migrationAdenosine receptor A1Homo sapiens (human)
positive regulation of peptide secretionAdenosine receptor A1Homo sapiens (human)
positive regulation of systemic arterial blood pressureAdenosine receptor A1Homo sapiens (human)
negative regulation of systemic arterial blood pressureAdenosine receptor A1Homo sapiens (human)
regulation of glomerular filtrationAdenosine receptor A1Homo sapiens (human)
protein targeting to membraneAdenosine receptor A1Homo sapiens (human)
phagocytosisAdenosine receptor A1Homo sapiens (human)
inflammatory responseAdenosine receptor A1Homo sapiens (human)
signal transductionAdenosine receptor A1Homo sapiens (human)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathwayAdenosine receptor A1Homo sapiens (human)
cell-cell signalingAdenosine receptor A1Homo sapiens (human)
nervous system developmentAdenosine receptor A1Homo sapiens (human)
negative regulation of cell population proliferationAdenosine receptor A1Homo sapiens (human)
response to inorganic substanceAdenosine receptor A1Homo sapiens (human)
negative regulation of glutamate secretionAdenosine receptor A1Homo sapiens (human)
response to purine-containing compoundAdenosine receptor A1Homo sapiens (human)
lipid catabolic processAdenosine receptor A1Homo sapiens (human)
negative regulation of synaptic transmission, GABAergicAdenosine receptor A1Homo sapiens (human)
positive regulation of nucleoside transportAdenosine receptor A1Homo sapiens (human)
negative regulation of neurotrophin productionAdenosine receptor A1Homo sapiens (human)
positive regulation of protein dephosphorylationAdenosine receptor A1Homo sapiens (human)
vasodilationAdenosine receptor A1Homo sapiens (human)
negative regulation of circadian sleep/wake cycle, non-REM sleepAdenosine receptor A1Homo sapiens (human)
negative regulation of apoptotic processAdenosine receptor A1Homo sapiens (human)
positive regulation of potassium ion transportAdenosine receptor A1Homo sapiens (human)
positive regulation of MAPK cascadeAdenosine receptor A1Homo sapiens (human)
negative regulation of hormone secretionAdenosine receptor A1Homo sapiens (human)
cognitionAdenosine receptor A1Homo sapiens (human)
leukocyte migrationAdenosine receptor A1Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of painAdenosine receptor A1Homo sapiens (human)
negative regulation of lipid catabolic processAdenosine receptor A1Homo sapiens (human)
positive regulation of lipid catabolic processAdenosine receptor A1Homo sapiens (human)
regulation of sensory perception of painAdenosine receptor A1Homo sapiens (human)
negative regulation of synaptic transmission, glutamatergicAdenosine receptor A1Homo sapiens (human)
fatty acid homeostasisAdenosine receptor A1Homo sapiens (human)
excitatory postsynaptic potentialAdenosine receptor A1Homo sapiens (human)
long-term synaptic depressionAdenosine receptor A1Homo sapiens (human)
mucus secretionAdenosine receptor A1Homo sapiens (human)
negative regulation of mucus secretionAdenosine receptor A1Homo sapiens (human)
triglyceride homeostasisAdenosine receptor A1Homo sapiens (human)
regulation of cardiac muscle cell contractionAdenosine receptor A1Homo sapiens (human)
apoptotic signaling pathwayAdenosine receptor A1Homo sapiens (human)
regulation of presynaptic cytosolic calcium ion concentrationAdenosine receptor A1Homo sapiens (human)
negative regulation of long-term synaptic potentiationAdenosine receptor A1Homo sapiens (human)
negative regulation of long-term synaptic depressionAdenosine receptor A1Homo sapiens (human)
G protein-coupled receptor signaling pathwayAdenosine receptor A1Homo sapiens (human)
adenosine catabolic processAdenosine deaminase Bos taurus (cattle)
cell adhesionAdenosine deaminase Bos taurus (cattle)
nucleotide metabolic processAdenosine deaminase Bos taurus (cattle)
purine ribonucleoside monophosphate biosynthetic processAdenosine deaminase Bos taurus (cattle)
inosine biosynthetic processAdenosine deaminase Bos taurus (cattle)
negative regulation of receptor internalizationAtaxin-2Homo sapiens (human)
regulation of translationAtaxin-2Homo sapiens (human)
RNA metabolic processAtaxin-2Homo sapiens (human)
P-body assemblyAtaxin-2Homo sapiens (human)
stress granule assemblyAtaxin-2Homo sapiens (human)
RNA transportAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (83)

Processvia Protein(s)Taxonomy
magnesium ion bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
3',5'-cyclic-AMP phosphodiesterase activitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cGMP-stimulated cyclic-nucleotide phosphodiesterase activitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
protein bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
zinc ion bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cAMP bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cGMP bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
TPR domain bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
phosphate ion bindingcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
protein homodimerization activitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
3',5'-cyclic-GMP phosphodiesterase activitycGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
aspartic-type endopeptidase activityReninHomo sapiens (human)
signaling receptor bindingReninHomo sapiens (human)
insulin-like growth factor receptor bindingReninHomo sapiens (human)
protein bindingReninHomo sapiens (human)
peptidase activityReninHomo sapiens (human)
fibroblast growth factor bindingIntegrin beta-3Homo sapiens (human)
C-X3-C chemokine bindingIntegrin beta-3Homo sapiens (human)
insulin-like growth factor I bindingIntegrin beta-3Homo sapiens (human)
neuregulin bindingIntegrin beta-3Homo sapiens (human)
virus receptor activityIntegrin beta-3Homo sapiens (human)
fibronectin bindingIntegrin beta-3Homo sapiens (human)
protease bindingIntegrin beta-3Homo sapiens (human)
protein disulfide isomerase activityIntegrin beta-3Homo sapiens (human)
protein kinase C bindingIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor bindingIntegrin beta-3Homo sapiens (human)
integrin bindingIntegrin beta-3Homo sapiens (human)
protein bindingIntegrin beta-3Homo sapiens (human)
coreceptor activityIntegrin beta-3Homo sapiens (human)
enzyme bindingIntegrin beta-3Homo sapiens (human)
identical protein bindingIntegrin beta-3Homo sapiens (human)
vascular endothelial growth factor receptor 2 bindingIntegrin beta-3Homo sapiens (human)
metal ion bindingIntegrin beta-3Homo sapiens (human)
cell adhesion molecule bindingIntegrin beta-3Homo sapiens (human)
extracellular matrix bindingIntegrin beta-3Homo sapiens (human)
fibrinogen bindingIntegrin beta-3Homo sapiens (human)
UTP bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
CTP bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
RNA bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
mRNA bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
protein bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
ATP bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
GTP bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
ATP hydrolysis activityHeat shock protein HSP 90-alphaHomo sapiens (human)
sulfonylurea receptor bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
protein phosphatase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
MHC class II protein complex bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
nitric-oxide synthase regulator activityHeat shock protein HSP 90-alphaHomo sapiens (human)
TPR domain bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
ubiquitin protein ligase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
dATP bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
identical protein bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
protein homodimerization activityHeat shock protein HSP 90-alphaHomo sapiens (human)
histone deacetylase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
transmembrane transporter bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
tau protein bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
GTPase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
Rho GDP-dissociation inhibitor bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
DNA polymerase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
scaffold protein bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
disordered domain specific bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
ATP-dependent protein folding chaperoneHeat shock protein HSP 90-alphaHomo sapiens (human)
protein tyrosine kinase bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
unfolded protein bindingHeat shock protein HSP 90-alphaHomo sapiens (human)
protein bindingIntegrin alpha-IIbHomo sapiens (human)
identical protein bindingIntegrin alpha-IIbHomo sapiens (human)
metal ion bindingIntegrin alpha-IIbHomo sapiens (human)
extracellular matrix bindingIntegrin alpha-IIbHomo sapiens (human)
molecular adaptor activityIntegrin alpha-IIbHomo sapiens (human)
fibrinogen bindingIntegrin alpha-IIbHomo sapiens (human)
integrin bindingIntegrin alpha-IIbHomo sapiens (human)
G protein-coupled adenosine receptor activityAdenosine receptor A3Homo sapiens (human)
RNA bindingEndoplasminHomo sapiens (human)
calcium ion bindingEndoplasminHomo sapiens (human)
protein bindingEndoplasminHomo sapiens (human)
ATP bindingEndoplasminHomo sapiens (human)
ATP hydrolysis activityEndoplasminHomo sapiens (human)
protein phosphatase bindingEndoplasminHomo sapiens (human)
low-density lipoprotein particle receptor bindingEndoplasminHomo sapiens (human)
ATP-dependent protein folding chaperoneEndoplasminHomo sapiens (human)
unfolded protein bindingEndoplasminHomo sapiens (human)
Gq/11-coupled serotonin receptor activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
virus receptor activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
G protein-coupled serotonin receptor activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
protein binding5-hydroxytryptamine receptor 2AHomo sapiens (human)
protein tyrosine kinase activator activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
identical protein binding5-hydroxytryptamine receptor 2AHomo sapiens (human)
protein-containing complex binding5-hydroxytryptamine receptor 2AHomo sapiens (human)
serotonin binding5-hydroxytryptamine receptor 2AHomo sapiens (human)
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding5-hydroxytryptamine receptor 2AHomo sapiens (human)
neurotransmitter receptor activity5-hydroxytryptamine receptor 2AHomo sapiens (human)
G protein-coupled adenosine receptor activityAdenosine receptor A2aHomo sapiens (human)
protein bindingAdenosine receptor A2aHomo sapiens (human)
calmodulin bindingAdenosine receptor A2aHomo sapiens (human)
lipid bindingAdenosine receptor A2aHomo sapiens (human)
enzyme bindingAdenosine receptor A2aHomo sapiens (human)
type 5 metabotropic glutamate receptor bindingAdenosine receptor A2aHomo sapiens (human)
identical protein bindingAdenosine receptor A2aHomo sapiens (human)
protein-containing complex bindingAdenosine receptor A2aHomo sapiens (human)
alpha-actinin bindingAdenosine receptor A2aHomo sapiens (human)
G protein-coupled adenosine receptor activityAdenosine receptor A2bHomo sapiens (human)
protein bindingAdenosine receptor A2bHomo sapiens (human)
G protein-coupled receptor activityAdenosine receptor A2bHomo sapiens (human)
G protein-coupled receptor bindingAdenosine receptor A1Homo sapiens (human)
purine nucleoside bindingAdenosine receptor A1Homo sapiens (human)
protein bindingAdenosine receptor A1Homo sapiens (human)
heat shock protein bindingAdenosine receptor A1Homo sapiens (human)
G-protein beta/gamma-subunit complex bindingAdenosine receptor A1Homo sapiens (human)
heterotrimeric G-protein bindingAdenosine receptor A1Homo sapiens (human)
protein heterodimerization activityAdenosine receptor A1Homo sapiens (human)
G protein-coupled adenosine receptor activityAdenosine receptor A1Homo sapiens (human)
G protein-coupled adenosine receptor activityAdenosine receptor A2aRattus norvegicus (Norway rat)
adenosine deaminase activityAdenosine deaminase Bos taurus (cattle)
protein bindingAdenosine deaminase Bos taurus (cattle)
zinc ion bindingAdenosine deaminase Bos taurus (cattle)
2'-deoxyadenosine deaminase activityAdenosine deaminase Bos taurus (cattle)
RNA bindingAtaxin-2Homo sapiens (human)
epidermal growth factor receptor bindingAtaxin-2Homo sapiens (human)
protein bindingAtaxin-2Homo sapiens (human)
mRNA bindingAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (88)

Processvia Protein(s)Taxonomy
plasma membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
nucleuscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cytoplasmcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
mitochondrial outer membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
mitochondrial inner membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
endoplasmic reticulumcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
Golgi apparatuscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cytosolcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
plasma membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
presynaptic membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
perinuclear region of cytoplasmcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
nucleuscGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
mitochondrial inner membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
perinuclear region of cytoplasmcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
mitochondrial outer membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
synaptic membranecGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
cytosolcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
mitochondrial matrixcGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)
extracellular regionReninHomo sapiens (human)
extracellular spaceReninHomo sapiens (human)
plasma membraneReninHomo sapiens (human)
apical part of cellReninHomo sapiens (human)
extracellular spaceReninHomo sapiens (human)
glutamatergic synapseIntegrin beta-3Homo sapiens (human)
nucleusIntegrin beta-3Homo sapiens (human)
nucleoplasmIntegrin beta-3Homo sapiens (human)
plasma membraneIntegrin beta-3Homo sapiens (human)
cell-cell junctionIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
external side of plasma membraneIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
apical plasma membraneIntegrin beta-3Homo sapiens (human)
platelet alpha granule membraneIntegrin beta-3Homo sapiens (human)
lamellipodium membraneIntegrin beta-3Homo sapiens (human)
filopodium membraneIntegrin beta-3Homo sapiens (human)
microvillus membraneIntegrin beta-3Homo sapiens (human)
ruffle membraneIntegrin beta-3Homo sapiens (human)
integrin alphav-beta3 complexIntegrin beta-3Homo sapiens (human)
melanosomeIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
postsynaptic membraneIntegrin beta-3Homo sapiens (human)
extracellular exosomeIntegrin beta-3Homo sapiens (human)
integrin alphaIIb-beta3 complexIntegrin beta-3Homo sapiens (human)
glycinergic synapseIntegrin beta-3Homo sapiens (human)
integrin complexIntegrin beta-3Homo sapiens (human)
protein-containing complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-HMGB1 complexIntegrin beta-3Homo sapiens (human)
receptor complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-vitronectin complexIntegrin beta-3Homo sapiens (human)
alpha9-beta1 integrin-ADAM8 complexIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
extracellular regionHeat shock protein HSP 90-alphaHomo sapiens (human)
nucleusHeat shock protein HSP 90-alphaHomo sapiens (human)
nucleoplasmHeat shock protein HSP 90-alphaHomo sapiens (human)
cytoplasmHeat shock protein HSP 90-alphaHomo sapiens (human)
mitochondrionHeat shock protein HSP 90-alphaHomo sapiens (human)
cytosolHeat shock protein HSP 90-alphaHomo sapiens (human)
plasma membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
cell surfaceHeat shock protein HSP 90-alphaHomo sapiens (human)
membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
basolateral plasma membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
apical plasma membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
brush border membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
secretory granule lumenHeat shock protein HSP 90-alphaHomo sapiens (human)
melanosomeHeat shock protein HSP 90-alphaHomo sapiens (human)
neuronal cell bodyHeat shock protein HSP 90-alphaHomo sapiens (human)
lysosomal lumenHeat shock protein HSP 90-alphaHomo sapiens (human)
dendritic growth coneHeat shock protein HSP 90-alphaHomo sapiens (human)
axonal growth coneHeat shock protein HSP 90-alphaHomo sapiens (human)
perinuclear region of cytoplasmHeat shock protein HSP 90-alphaHomo sapiens (human)
collagen-containing extracellular matrixHeat shock protein HSP 90-alphaHomo sapiens (human)
extracellular exosomeHeat shock protein HSP 90-alphaHomo sapiens (human)
endocytic vesicle lumenHeat shock protein HSP 90-alphaHomo sapiens (human)
sperm mitochondrial sheathHeat shock protein HSP 90-alphaHomo sapiens (human)
sperm plasma membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
ficolin-1-rich granule lumenHeat shock protein HSP 90-alphaHomo sapiens (human)
protein-containing complexHeat shock protein HSP 90-alphaHomo sapiens (human)
plasma membraneHeat shock protein HSP 90-alphaHomo sapiens (human)
neuronal cell bodyHeat shock protein HSP 90-alphaHomo sapiens (human)
perinuclear region of cytoplasmHeat shock protein HSP 90-alphaHomo sapiens (human)
myelin sheathHeat shock protein HSP 90-alphaHomo sapiens (human)
cytosolHeat shock protein HSP 90-alphaHomo sapiens (human)
nucleusHeat shock protein HSP 90-alphaHomo sapiens (human)
plasma membraneIntegrin alpha-IIbHomo sapiens (human)
focal adhesionIntegrin alpha-IIbHomo sapiens (human)
cell surfaceIntegrin alpha-IIbHomo sapiens (human)
platelet alpha granule membraneIntegrin alpha-IIbHomo sapiens (human)
extracellular exosomeIntegrin alpha-IIbHomo sapiens (human)
integrin alphaIIb-beta3 complexIntegrin alpha-IIbHomo sapiens (human)
blood microparticleIntegrin alpha-IIbHomo sapiens (human)
integrin complexIntegrin alpha-IIbHomo sapiens (human)
external side of plasma membraneIntegrin alpha-IIbHomo sapiens (human)
plasma membraneAdenosine receptor A3Homo sapiens (human)
presynaptic membraneAdenosine receptor A3Homo sapiens (human)
Schaffer collateral - CA1 synapseAdenosine receptor A3Homo sapiens (human)
dendriteAdenosine receptor A3Homo sapiens (human)
plasma membraneAdenosine receptor A3Homo sapiens (human)
synapseAdenosine receptor A3Homo sapiens (human)
extracellular regionEndoplasminHomo sapiens (human)
nucleusEndoplasminHomo sapiens (human)
endoplasmic reticulumEndoplasminHomo sapiens (human)
endoplasmic reticulum lumenEndoplasminHomo sapiens (human)
endoplasmic reticulum membraneEndoplasminHomo sapiens (human)
smooth endoplasmic reticulumEndoplasminHomo sapiens (human)
cytosolEndoplasminHomo sapiens (human)
focal adhesionEndoplasminHomo sapiens (human)
membraneEndoplasminHomo sapiens (human)
midbodyEndoplasminHomo sapiens (human)
sarcoplasmic reticulum lumenEndoplasminHomo sapiens (human)
melanosomeEndoplasminHomo sapiens (human)
perinuclear region of cytoplasmEndoplasminHomo sapiens (human)
collagen-containing extracellular matrixEndoplasminHomo sapiens (human)
extracellular exosomeEndoplasminHomo sapiens (human)
endocytic vesicle lumenEndoplasminHomo sapiens (human)
sperm plasma membraneEndoplasminHomo sapiens (human)
protein-containing complexEndoplasminHomo sapiens (human)
endoplasmic reticulum chaperone complexEndoplasminHomo sapiens (human)
endoplasmic reticulumEndoplasminHomo sapiens (human)
perinuclear region of cytoplasmEndoplasminHomo sapiens (human)
neurofilament5-hydroxytryptamine receptor 2AHomo sapiens (human)
plasma membrane5-hydroxytryptamine receptor 2AHomo sapiens (human)
caveola5-hydroxytryptamine receptor 2AHomo sapiens (human)
axon5-hydroxytryptamine receptor 2AHomo sapiens (human)
cytoplasmic vesicle5-hydroxytryptamine receptor 2AHomo sapiens (human)
presynaptic membrane5-hydroxytryptamine receptor 2AHomo sapiens (human)
neuronal cell body5-hydroxytryptamine receptor 2AHomo sapiens (human)
dendritic shaft5-hydroxytryptamine receptor 2AHomo sapiens (human)
postsynaptic membrane5-hydroxytryptamine receptor 2AHomo sapiens (human)
cell body fiber5-hydroxytryptamine receptor 2AHomo sapiens (human)
glutamatergic synapse5-hydroxytryptamine receptor 2AHomo sapiens (human)
G protein-coupled serotonin receptor complex5-hydroxytryptamine receptor 2AHomo sapiens (human)
plasma membrane5-hydroxytryptamine receptor 2AHomo sapiens (human)
dendrite5-hydroxytryptamine receptor 2AHomo sapiens (human)
plasma membraneAdenosine receptor A2aHomo sapiens (human)
intermediate filamentAdenosine receptor A2aHomo sapiens (human)
plasma membraneAdenosine receptor A2aHomo sapiens (human)
membraneAdenosine receptor A2aHomo sapiens (human)
dendriteAdenosine receptor A2aHomo sapiens (human)
axolemmaAdenosine receptor A2aHomo sapiens (human)
asymmetric synapseAdenosine receptor A2aHomo sapiens (human)
presynaptic membraneAdenosine receptor A2aHomo sapiens (human)
neuronal cell bodyAdenosine receptor A2aHomo sapiens (human)
postsynaptic membraneAdenosine receptor A2aHomo sapiens (human)
presynaptic active zoneAdenosine receptor A2aHomo sapiens (human)
glutamatergic synapseAdenosine receptor A2aHomo sapiens (human)
plasma membraneAdenosine receptor A2bHomo sapiens (human)
Schaffer collateral - CA1 synapseAdenosine receptor A2bHomo sapiens (human)
presynapseAdenosine receptor A2bHomo sapiens (human)
glutamatergic synapseAdenosine receptor A2bHomo sapiens (human)
plasma membraneAdenosine receptor A2bHomo sapiens (human)
plasma membraneAdenosine receptor A1Homo sapiens (human)
plasma membraneAdenosine receptor A1Homo sapiens (human)
basolateral plasma membraneAdenosine receptor A1Homo sapiens (human)
axolemmaAdenosine receptor A1Homo sapiens (human)
asymmetric synapseAdenosine receptor A1Homo sapiens (human)
presynaptic membraneAdenosine receptor A1Homo sapiens (human)
neuronal cell bodyAdenosine receptor A1Homo sapiens (human)
terminal boutonAdenosine receptor A1Homo sapiens (human)
dendritic spineAdenosine receptor A1Homo sapiens (human)
calyx of HeldAdenosine receptor A1Homo sapiens (human)
postsynaptic membraneAdenosine receptor A1Homo sapiens (human)
presynaptic active zoneAdenosine receptor A1Homo sapiens (human)
synapseAdenosine receptor A1Homo sapiens (human)
dendriteAdenosine receptor A1Homo sapiens (human)
Golgi membraneAdenosine receptor A2aRattus norvegicus (Norway rat)
lysosomeAdenosine deaminase Bos taurus (cattle)
cytoplasmic vesicle lumenAdenosine deaminase Bos taurus (cattle)
anchoring junctionAdenosine deaminase Bos taurus (cattle)
cytoplasmAtaxin-2Homo sapiens (human)
Golgi apparatusAtaxin-2Homo sapiens (human)
trans-Golgi networkAtaxin-2Homo sapiens (human)
cytosolAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
membraneAtaxin-2Homo sapiens (human)
perinuclear region of cytoplasmAtaxin-2Homo sapiens (human)
ribonucleoprotein complexAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (168)

Assay IDTitleYearJournalArticle
AID588461High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588461High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588461High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588460High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588460High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588460High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588459High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588459High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588459High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID232472Selectivity ratio for A1 receptor to that of A2 receptor in vitro in rat tissues1989Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.
AID78489Antagonist binding of N6-cyclohexyl-[3H]-adenosine to guinea pig brain1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID1694546Displacement of FITC-geldanamycin from GRP94 (unknown origin) after 24 hrs by fluorescence polarization assay2021ACS medicinal chemistry letters, Mar-11, Volume: 12, Issue:3
Biological Evaluation of 5'-(
AID205268Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex at 10 uM1985Journal of medicinal chemistry, Mar, Volume: 28, Issue:3
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
AID155645Percentage of apoptotic cells in human peripheral blood mononuclear cells after 72 hour incubation at the concentration 30 uM1998Bioorganic & medicinal chemistry letters, Sep-22, Volume: 8, Issue:18
Modulation of apoptosis in human lymphocytes by adenosine analogues.
AID1578771Antimalarial activity against Plasmodium falciparum FCQ-27 isolate infected in erythrocytes assessed as reduction in [G-3H]Hypoxanthine incorporation incubated for 24 hrs followed by addition of [G-3H]Hypoxanthine and measured after 18 to 20 hrs by scinti2019Journal of medicinal chemistry, 09-26, Volume: 62, Issue:18
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
AID33590Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membrane1985Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists.
AID1694550Selectivity index, ratio of Kd for displacement of FITC-geldanamycin from GRP94 (unknown origin) after 24 hrs by fluorescence polarization assay to Kd for displacement of FITC-geldanamycin from HSP90alpha (unknown origin) after 24 hrs by fluorescence pola2021ACS medicinal chemistry letters, Mar-11, Volume: 12, Issue:3
Biological Evaluation of 5'-(
AID524792Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID33939Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranes1994Journal of medicinal chemistry, Oct-14, Volume: 37, Issue:21
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
AID34581Binding affinity at Mutant (H272E) human adenosine A3 receptor expressed in COS-7 cells2001Journal of medicinal chemistry, Nov-22, Volume: 44, Issue:24
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
AID30507Coronary arteries vasodilation at the adenosine A2 receptor in langendorff guinea pig heart preparation1991Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.
AID34159Inhibition of adenyl cyclase via P site in adipocytes; Inactive1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID179751In vitro inhibition of synaptic potential in the hippocampal formation (synaptic responses (fEPSPs) recorded in the CAI region of in vivo hippocampal slices in rat brain)1992Journal of medicinal chemistry, Oct-30, Volume: 35, Issue:22
Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
AID1138014Agonist activity at human recombinant adenosine receptor A2b by cAMP assay2014Journal of medicinal chemistry, May-08, Volume: 57, Issue:9
Adenosine A2A receptor as a drug discovery target.
AID34272Percent efficacy against human Adenosine A3 receptor expressed in CHO cell2002Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
AID32206Displacement of [3H]CHA from adenosine A1 receptor of rat whole brain1985Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists.
AID33482Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranes1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID1452135Selectivity ratio of IC50 for human full length C-terminal His-tagged Hsp90 alpha expressed in Escherichia coli to IC50 for Thermotoga maritima His-tagged HK853 expressed in Escherichia coli BL21(DE3)pLysS Rosetta2017Journal of medicinal chemistry, 10-12, Volume: 60, Issue:19
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
AID229821Ratio of Ki for A1 and A3 receptors1994Journal of medicinal chemistry, Oct-14, Volume: 37, Issue:21
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
AID33752Ratio of A2 to A1.1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
AID31850Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptor1992Journal of medicinal chemistry, Oct-30, Volume: 35, Issue:22
Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
AID33588Binding affinity towards adenosine A2 receptor on rat striatal membrane using [3H]NECA as radioligand1988Journal of medicinal chemistry, Jan, Volume: 31, Issue:1
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.
AID96710Compound was tested for cytotoxicity against L1210 cell lines1992Journal of medicinal chemistry, Jan-24, Volume: 35, Issue:2
Synthesis and biologic activity of 2'-fluoro-2-halo derivatives of 9-beta-D-arabinofuranosyladenine.
AID175313Reduction of heart rate (A1 response) in isolated rat heart preparation1988Journal of medicinal chemistry, Jan, Volume: 31, Issue:1
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.
AID372174Displacement of [125I]I-ABOPX from human recombinant adenosine A2B receptor expressed in HEK293 cells2009Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
AID1324458Displacement of [3H]GR113808 from human 5-HT4 receptor at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID33405Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptor1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
AID32195Binding affinity towards adenosine A1 receptor on rat whole brain membrane using [3H]N6-cyclohexyladenosine1988Journal of medicinal chemistry, Jan, Volume: 31, Issue:1
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.
AID196738Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fat1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID32180Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptor1991Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
AID1452134Inhibition of full length human C-terminal His-tagged Hsp90 alpha expressed in Escherichia coli by fluorescence polarization assay2017Journal of medicinal chemistry, 10-12, Volume: 60, Issue:19
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
AID338164Displacement of [3H]CPX from adenosine A1 receptor assessed as specific binding relative to total binding1993Journal of natural products, Apr, Volume: 56, Issue:4
The role of receptor binding in drug discovery.
AID155782Percentage of apoptotic cells in human peripheral blood mononuclear cells after 72 hour incubation at the concentration 60 uM1998Bioorganic & medicinal chemistry letters, Sep-22, Volume: 8, Issue:18
Modulation of apoptosis in human lymphocytes by adenosine analogues.
AID1065710Displacement of [2,8-3H]-adenosine from Trypanosoma brucei AT1/P2 expressed in bloodstream stage of Trypanosoma brucei brucei B482013Journal of medicinal chemistry, Dec-27, Volume: 56, Issue:24
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
AID32639Ratio of IC50 values for A1 receptor binding to that of A2 receptor1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
AID554262Inhibition of calf placental adenosine deaminase by Lineweaver-Burk plot analysis2011Journal of medicinal chemistry, Jan-13, Volume: 54, Issue:1
Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.
AID42825Antagonist binding of N6-cyclohexyl-[3H]-adenosine to bovine brain1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID524790Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID155644Percentage of apoptotic cells in human peripheral blood mononuclear cells after 72 hour incubation at the concentration 10 uM1998Bioorganic & medicinal chemistry letters, Sep-22, Volume: 8, Issue:18
Modulation of apoptosis in human lymphocytes by adenosine analogues.
AID233379Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 2A receptor.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID1324456Displacement of [3H]5-CT from human 5-HT1D receptor expressed in HEK-T cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID30510Antagonism of cyclic [3H]AMP accumulation elicited by 15 uM 2-chloroadenosine in [3H]adenine-labeled guinea pig cerebral cortical slices at A2 receptor1985Journal of medicinal chemistry, Apr, Volume: 28, Issue:4
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
AID31410Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptor1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
AID81745Compound was tested for cytotoxicity against HEp-2 cell lines1992Journal of medicinal chemistry, Jan-24, Volume: 35, Issue:2
Synthesis and biologic activity of 2'-fluoro-2-halo derivatives of 9-beta-D-arabinofuranosyladenine.
AID445468Inhibition of [3H]adenine binding to adenine 1 receptor in rat brain cortical membrane at 100 uM by liquid scintillation counting2009Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
AID1324454Displacement of [3H]WAY100635 from human 5-HT1AR expressed in CHO cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID175310Enhancement of coronary flow (A2 response) in isolated rat heart preparation1988Journal of medicinal chemistry, Jan, Volume: 31, Issue:1
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.
AID337880Displacement of [3H]CPX from adenosine A1 receptor1993Journal of natural products, Apr, Volume: 56, Issue:4
The role of receptor binding in drug discovery.
AID524794Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID230000Ratio of Ki for A2a and A3 receptors1994Journal of medicinal chemistry, Oct-14, Volume: 37, Issue:21
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
AID1324516Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK-T cell membranes incubated for 90 mins under dark condition by microbeta scintillation counting method
AID31885Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.1995Journal of medicinal chemistry, Mar-31, Volume: 38, Issue:7
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
AID33733Inhibition of binding of [3H]NECA to adenosine A2 receptor of rat striatal membranes.1989Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.
AID195541Antagonist binding of 2-chloro-[3H]-adenosine in rat brain1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID33746Binding affinity against adenosine A2 receptor using [3H]- NECA as radioligand1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
AID521220Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay2007Nature chemical biology, May, Volume: 3, Issue:5
Chemical genetics reveals a complex functional ground state of neural stem cells.
AID32513Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranes1994Journal of medicinal chemistry, Oct-14, Volume: 37, Issue:21
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
AID1324457Displacement of [3H]5-HT from human 5-HT1E receptor expressed in HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID233377Inhibitory selectivity at Adenosine 2A receptor compared to Adenosine 1 receptor.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID155643Percentage of apoptotic cells in human peripheral blood mononuclear cells after 72 hour incubation at the concentration 1 uM1998Bioorganic & medicinal chemistry letters, Sep-22, Volume: 8, Issue:18
Modulation of apoptosis in human lymphocytes by adenosine analogues.
AID248027In vitro inhibitory activity against human colon carcinoma HT-29 cell line2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.
AID194219Change in heart rate was expressed in percent at at a dose 0.017 mg/kg iv in anesthetized rat1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
AID1138018Binding affinity to human recombinant adenosine A3 receptor2014Journal of medicinal chemistry, May-08, Volume: 57, Issue:9
Adenosine A2A receptor as a drug discovery target.
AID524795Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID195543Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat brain1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID524796Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID247910In vitro inhibitory activity against human leukemia K562IU cell line2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.
AID34582Concentration required to increase Adenosine A2A receptor mediated P12 Adenylate cyclase activity1991Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
AID445467Displacement of [3H]adenine from adenine 1 receptor in rat brain cortical membrane by liquid scintillation counting2009Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
AID229799Ratio of Ki at adenosine A2 and A1 receptors1988Journal of medicinal chemistry, Jan, Volume: 31, Issue:1
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.
AID330859Agonist activity human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase relative to NECA2008Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.
AID34265Effect on forskolin-stimulated cyclic AMP production in intact chinese hamster ovary (CHO) cell expressing the human Adenosine A3 receptor2002Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
AID1324455Displacement of [3H]5-CT from human 5-HT1BR expressed in HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID1324461Displacement of [3H]GR65630 from human 5-HT3 receptor expressed in HEK-T cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID1138011Binding affinity to human recombinant adenosine receptor A2a2014Journal of medicinal chemistry, May-08, Volume: 57, Issue:9
Adenosine A2A receptor as a drug discovery target.
AID33018Ratio of binding potencies at Adenosine A2A receptor and Adenosine A1A receptor1991Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
AID33928Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID32189Binding affinity towards adenosine A1 receptor in rat brain cortex2001Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
Design, synthesis, and evaluation of novel A2A adenosine receptor agonists.
AID1368375Inhibition of recombinant human PDE2A catalytic domain (580 to 919 residues) expressed in Escherichia coli BL21 (Codonplus) using [3H]cGMP as substrate after 15 mins by liquid scintillation counting method2018Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1
Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.
AID32177Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligand1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
AID205269Inhibition of binding of Batrachotoxinin [3H]BTX-B to high-affinity sites on voltage-dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex at 100 uM1985Journal of medicinal chemistry, Mar, Volume: 28, Issue:3
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
AID232382Ratio of EC50 stim-QRS (conduction block) and EC50 for vasodilation of coronary arteries1991Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.
AID1324467Displacement of [3H]mesulergine from human 5-HT2CR expressed in Flp-In HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID1324465Displacement of [3H]lysergic from human 5-HT2BR expressed in HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID1324460Displacement of [3H]LSD from human 5-HT7A receptor expressed in HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID229446Relative binding to A2 and A1 receptors (ratio of Ki)1985Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists.
AID32148Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparation1991Journal of medicinal chemistry, Apr, Volume: 34, Issue:4
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.
AID34574Affinity for human Adenosine A3 receptor expressed in CHO cell2002Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
AID32879Binding affinity towards adenosine A2A receptor in rat brain striatum2001Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
Design, synthesis, and evaluation of novel A2A adenosine receptor agonists.
AID44000Compound was tested for cytotoxicity against CCRF-CEM cell lines1992Journal of medicinal chemistry, Jan-24, Volume: 35, Issue:2
Synthesis and biologic activity of 2'-fluoro-2-halo derivatives of 9-beta-D-arabinofuranosyladenine.
AID233378Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 1 receptor.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID1452136Inhibition of full length human C-terminal His-tagged Hsp90 alpha expressed in Escherichia coli at 1.25 mM by fluorescence polarization assay relative to control2017Journal of medicinal chemistry, 10-12, Volume: 60, Issue:19
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
AID32002Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
AID195542Antagonist binding of 2-chloro-[3H]-adenosine to rat brain1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID1324459Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID34704Binding affinity at wild-type Adenosine A3 receptor expressed in COS-7 cells2001Journal of medicinal chemistry, Nov-22, Volume: 44, Issue:24
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
AID1324463Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK-T cell membranes at 10 uM incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID33337Binding affinity determined by displacement of specific binding of [125I]N-(4-amino-3-iodophenethyl)-adenosine in membranes of CHO cells stably transfected with the rat adenosine A3 receptor1995Journal of medicinal chemistry, Mar-31, Volume: 38, Issue:7
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
AID1694547Displacement of FITC-geldanamycin from HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assay2021ACS medicinal chemistry letters, Mar-11, Volume: 12, Issue:3
Biological Evaluation of 5'-(
AID30353Affinity constant for inhibition of A1 receptor control of adenylate cyclase in adipocytes, heart and brain cells1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID330858Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase2008Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.
AID32872Inhibition of [3H]- NECA binding to adenosine receptor A2A1991Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
AID248110In vitro inhibitory activity against human myelogenous leukemia K562 cell line2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.
AID17397425% reduction in blood pressure in the rat.1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
AID1138015Binding affinity to human recombinant adenosine A1 receptor2014Journal of medicinal chemistry, May-08, Volume: 57, Issue:9
Adenosine A2A receptor as a drug discovery target.
AID32503Inhibition of binding of [3H]N6-cyclohexyladenosine to adenosine A1 receptor of rat whole brain membranes.1989Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.
AID33910Affinity constant for A2 receptor control of adenylate cyclase in adipocytes, heart and brain cells; 5-10 uM1982Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
Adenosine receptors: targets for future drugs.
AID1452128Inhibition of ATPgammaS-BODIPY binding to Thermotoga maritima His-tagged HK853 expressed in Escherichia coli BL21(DE3)pLysS Rosetta preincubated for 30 mins prior to ATPgammaS-BODIPY addition measured after 1 hr by coomassie staining-based SDS-PAGE analys2017Journal of medicinal chemistry, 10-12, Volume: 60, Issue:19
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
AID524791Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID1324468Displacement of [3H]N6-phenylisopropyladenosine from recombinant human A1AR expressed in CHO cell membranes after 60 mins by liquid scintillation counting method
AID372151Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells2009Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
AID248043In vitro inhibitory activity against human breast carcinoma MCF-7 cell line2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.
AID33485Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO cells transfected with rat A3-cDNA1994Journal of medicinal chemistry, Oct-14, Volume: 37, Issue:21
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
AID1368376Inhibition of recombinant human PDE2A catalytic domain (580 to 919 residues) expressed in Escherichia coli BL21 (Codonplus) at 1 uM using [3H]cGMP as substrate after 15 mins by liquid scintillation counting method relative to control2018Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1
Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.
AID1324462Displacement of [3H]LSD from human 5-HT5A receptor expressed in Flp-In-CHO cell membranes incubated for 90 mins under dark condition by microbeta scintillation counting method relative to control
AID33792Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligand1995Journal of medicinal chemistry, Mar-31, Volume: 38, Issue:7
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID588378qHTS for Inhibitors of ATXN expression: Validation
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID1345618Human A2A receptor (Adenosine receptors)1995The Journal of biological chemistry, Jun-09, Volume: 270, Issue:23
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
AID1345831Rat A3 receptor (Adenosine receptors)1994Molecular pharmacology, Jun, Volume: 45, Issue:6
A binding site model and structure-activity relationships for the rat A3 adenosine receptor.
AID1345690Rat A2A receptor (Adenosine receptors)1993Pharmacology, , Volume: 46, Issue:2
Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors.
AID1345630Rat A1 receptor (Adenosine receptors)1993Pharmacology, , Volume: 46, Issue:2
Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors.
AID1345685Human A1 receptor (Adenosine receptors)1999The Journal of biological chemistry, Feb-05, Volume: 274, Issue:6
Identification of the adenine binding site of the human A1 adenosine receptor.
AID1345721Human A2B receptor (Adenosine receptors)1980Canadian journal of physiology and pharmacology, Jun, Volume: 58, Issue:6
Adenosine receptor activation in human fibroblasts: nucleoside agonists and antagonists.
AID1345721Human A2B receptor (Adenosine receptors)2000Molecular pharmacology, Dec, Volume: 58, Issue:6
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
AID1345685Human A1 receptor (Adenosine receptors)1994The Journal of biological chemistry, Dec-23, Volume: 269, Issue:51
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
AID1345721Human A2B receptor (Adenosine receptors)1999Molecular pharmacology, Oct, Volume: 56, Issue:4
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
AID1345618Human A2A receptor (Adenosine receptors)1999Biochemical pharmacology, Jan-01, Volume: 57, Issue:1
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
AID1224864HCS microscopy assay (F508del-CFTR)2016PloS one, , Volume: 11, Issue:10
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (862)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990307 (35.61)18.7374
1990's343 (39.79)18.2507
2000's148 (17.17)29.6817
2010's52 (6.03)24.3611
2020's12 (1.39)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials13 (1.46%)5.53%
Reviews22 (2.47%)6.00%
Case Studies15 (1.69%)4.05%
Observational0 (0.00%)0.25%
Other839 (94.38%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
adenosine[no description available]medium5090adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
n(6)-phenyladenosine[no description available]medium80purine nucleoside
adenosine amine congener[no description available]medium20
adenosine-5'-(n-ethylcarboxamide)[no description available]medium1430adenosines;
monocarboxylic acid amide		adenosine A1 receptor agonist;
adenosine A2A receptor agonist;
antineoplastic agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
n(6)-cyclopentyladenosine[no description available]medium440
2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine[no description available]medium400adenosines;
dicarboxylic acid monoamide;
monocarboxylic acid		adenosine A2A receptor agonist;
anti-inflammatory agent
n(6)-cyclohexyladenosine[no description available]medium490
cladribine[no description available]medium540organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
cladribine[no description available]medium547organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
clofarabine[no description available]medium30adenosines;
organofluorine compound		antimetabolite;
antineoplastic agent
2'-deoxy-2-fluoroadenosine[no description available]medium10adenosines;
organofluorine compound
fludarabine[no description available]medium200purine nucleoside
fludarabine[no description available]medium201purine nucleoside
2-bromo-2'-deoxyadenosine[no description available]medium10
1,3-dipropyl-8-cyclopentylxanthine[no description available]medium450oxopurineadenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
8-(4-sulfophenyl)theophylline[no description available]medium250
8-cyclopentyl-1,3-dimethylxanthine[no description available]medium50oxopurine
8-phenyltheophylline[no description available]medium490
theophylline[no description available]medium1390dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
caffeine[no description available]medium380purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
cgs 15943[no description available]medium110aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline		adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant
8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine[no description available]medium80
rolofylline[no description available]medium10oxopurine
1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine[no description available]medium40
phenylisopropyladenosine[no description available]medium200aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent
3,7-dimethyl-1-propargylxanthine[no description available]medium60
2-chloro-n(6)cyclopentyladenosine[no description available]medium100
cp 66713[no description available]medium10
8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine[no description available]medium10
8-(dicyclopropylmethyl)-1,3-dipropylxanthine[no description available]medium10
kfm 19[no description available]medium10
2-(1-octynyl)adenosine[no description available]medium10
8-cyclohexylcaffeine[no description available]medium20
2-((2-aminoethylamino)carbonylethylphenylethylamino)-5'-n-ethylcarboxamidoadenosine[no description available]medium30
cv 1808[no description available]medium130purine nucleoside
n(6)-(2,2-diphenylethyl)adenosine[no description available]medium40
cgs 24012[no description available]medium50
n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer[no description available]medium70
isoguanosine[no description available]medium20purine nucleoside
quinacrine[no description available]medium50acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
gallopamil[no description available]medium20benzenes;
organic amino compound
4-aminopyridine[no description available]medium70aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
phenytoin[no description available]medium30imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
amitriptyline[no description available]medium10carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
anisindione[no description available]medium20aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
baclofen[no description available]medium110amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
benzocaine[no description available]medium10benzoate ester;
substituted aniline		allergen;
antipruritic drug;
sensitiser;
topical anaesthetic
bepridil[no description available]medium20pyrrolidines;
tertiary amine		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
biperiden[no description available]medium10piperidines;
tertiary alcohol;
tertiary amino compound		antidote to sarin poisoning;
antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist;
parasympatholytic
bupivacaine[no description available]medium10aromatic amide;
piperidinecarboxamide;
tertiary amino compound
buspirone[no description available]medium10azaspiro compound;
N-alkylpiperazine;
N-arylpiperazine;
organic heteropolycyclic compound;
piperidones;
pyrimidines		anxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
butacaine[no description available]medium20benzoate ester
butamben[no description available]medium20amino acid ester;
benzoate ester;
primary amino compound;
substituted aniline		local anaesthetic
verapamil[no description available]medium50aromatic ether;
nitrile;
polyether;
tertiary amino compound
carbamazepine[no description available]medium90dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
chlordiazepoxide[no description available]medium40benzodiazepine
chlorpheniramine[no description available]medium10monochlorobenzenes;
pyridines;
tertiary amino compound		anti-allergic agent;
antidepressant;
antipruritic drug;
H1-receptor antagonist;
histamine antagonist;
serotonin uptake inhibitor
chlorpromazine[no description available]medium10organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
cimetidine[no description available]medium50aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
clomipramine[no description available]medium10dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor
cyproheptadine[no description available]medium10piperidines;
tertiary amine		anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist
desipramine[no description available]medium40dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
diazepam[no description available]medium901,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
diazoxide[no description available]medium30benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent
dibucaine[no description available]medium30aromatic ether;
monocarboxylic acid amide;
tertiary amino compound		topical anaesthetic
dicyclomine[no description available]medium10carboxylic ester;
tertiary amine		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
diphenidol[no description available]medium10benzenes;
piperidines;
tertiary alcohol		antiemetic
dilazep[no description available]medium50benzoate ester;
diazepane;
diester;
methoxybenzenes		cardioprotective agent;
platelet aggregation inhibitor;
vasodilator agent
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
dipyridamole[no description available]medium450piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
doxepin[no description available]medium10dibenzooxepine;
tertiary amino compound		antidepressant
droperidol[no description available]medium40aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
etazolate[no description available]medium10ethyl ester;
hydrazone;
pyrazolopyridine		alpha-secretase activator;
antidepressant;
antipsychotic agent;
anxiolytic drug;
GABA agent;
neuroprotective agent;
phosphodiesterase IV inhibitor
felodipine[no description available]medium40dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
flufenamic acid[no description available]medium20aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
fluphenazine[no description available]medium10N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
flumazenil[no description available]medium70ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
haloperidol[no description available]medium90aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
hydroxyzine[no description available]medium10hydroxyether;
monochlorobenzenes;
N-alkylpiperazine		anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist
lidocaine[no description available]medium30benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
ici 118551[no description available]medium10indanes
imipramine[no description available]medium40dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
indomethacin[no description available]medium120aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
1-methyl-3-isobutylxanthine[no description available]medium3903-isobutyl-1-methylxanthine
loperamide[no description available]medium10monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
mepivacaine[no description available]medium10piperidinecarboxamidedrug allergen;
local anaesthetic
benzoic acid [2-methyl-2-(propylamino)propyl] ester[no description available]medium10benzoate ester
metoprolol[no description available]medium20aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
mianserin[no description available]medium20dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist
nifedipine[no description available]medium80C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nisoldipine[no description available]medium10C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester
nitrendipine[no description available]medium40C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
nortriptyline[no description available]medium10organic tricyclic compound;
secondary amine		adrenergic uptake inhibitor;
analgesic;
antidepressant;
antineoplastic agent;
apoptosis inducer;
drug metabolite
oxethazaine[no description available]medium10amino acid amide
benoxinate[no description available]medium10amino acid ester;
benzoate ester;
substituted aniline;
tertiary amino compound		drug allergen;
local anaesthetic;
topical anaesthetic
papaverine[no description available]medium40benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
pentobarbital[no description available]medium30barbituratesGABAA receptor agonist
pheniramine[no description available]medium10pyridines;
tertiary amino compound
phenobarbital[no description available]medium10barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
phenoxybenzamine[no description available]medium10aromatic amine
practolol[no description available]medium10acetamides;
ethanolamines;
propanolamine;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
beta-adrenergic antagonist
pramoxine[no description available]medium10aromatic ether;
morpholines		local anaesthetic
prazosin[no description available]medium40aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
prilocaine[no description available]medium10amino acid amide;
monocarboxylic acid amide		anticonvulsant;
local anaesthetic
proadifen[no description available]medium10diarylmethane
procainamide[no description available]medium10benzamidesanti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker
procaine[no description available]medium10benzoate ester;
substituted aniline;
tertiary amino compound		central nervous system depressant;
drug allergen;
local anaesthetic;
peripheral nervous system drug
promazine[no description available]medium10phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
promethazine[no description available]medium10phenothiazines;
tertiary amine		anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative
proxymetacaine[no description available]medium10benzoate ester
protriptyline[no description available]medium10carbotricyclic compoundantidepressant
pyrilamine[no description available]medium40aromatic ether;
ethylenediamine derivative		H1-receptor antagonist
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone[no description available]medium80methoxybenzenes
rolipram[no description available]medium110pyrrolidin-2-onesantidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
secobarbital[no description available]medium10barbituratesanaesthesia adjuvant;
GABA modulator;
sedative
sotalol[no description available]medium10ethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide		anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
spiperone[no description available]medium30aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
tetracaine[no description available]medium10benzoate ester;
tertiary amino compound		local anaesthetic
thioridazine[no description available]medium10phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
trazodone[no description available]medium10monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazolopyridine		adrenergic antagonist;
antidepressant;
anxiolytic drug;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
trequinsin[no description available]medium10pyridopyrimidine
trifluoperazine[no description available]medium10N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines		antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug
reserpine[no description available]medium50alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
phentolamine[no description available]medium40imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
hexobendine[no description available]medium10trihydroxybenzoic acid
dichloroisoproterenol[no description available]medium10
tetraethylammonium chloride[no description available]medium30organic chloride salt;
quaternary ammonium salt		potassium channel blocker
tetrabenazine[no description available]medium20benzoquinolizine;
cyclic ketone;
tertiary amino compound
piperoxan[no description available]medium10
nifenalol[no description available]medium10C-nitro compound
brompheniramine[no description available]medium10organobromine compound;
pyridines		anti-allergic agent;
H1-receptor antagonist
propoxycaine[no description available]medium10benzoate ester
dimethisoquin[no description available]medium10isoquinolines
parethoxycaine[no description available]medium10benzoate ester
yohimbine[no description available]medium50methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
prenylamine[no description available]medium10diarylmethane
bicuculline[no description available]medium70benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
hexylcaine[no description available]medium10benzoate ester
piperocaine[no description available]medium10benzoate ester
diperodon[no description available]medium10carbamate ester
cyclomethycaine[no description available]medium10benzoate ester
carcainium chloride[no description available]medium10
azacyclonol[no description available]medium20diarylmethane
butoxamine[no description available]medium10
dexpropranolol[no description available]medium10propranolol
iprindole[no description available]medium10indoles
carticaine[no description available]medium10thiophenecarboxylic acid
timolol[no description available]medium10timololanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
butaclamol[no description available]medium10organic heteropentacyclic compound
etidocaine[no description available]medium10amino acid amidelocal anaesthetic
diltiazem[no description available]medium105-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetateantihypertensive agent;
calcium channel blocker;
vasodilator agent
Arbaclofen[no description available]medium10organonitrogen compound;
organooxygen compound
colforsin[no description available]medium530acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
opromazine[no description available]medium10phenothiazines
corynanthine[no description available]medium10yohimban alkaloid
w 7[no description available]medium20
2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene[no description available]medium10
rac 109[no description available]medium10
atropine[no description available]medium60
strychnine[no description available]medium10monoterpenoid indole alkaloid;
organic heteroheptacyclic compound		avicide;
cholinergic antagonist;
glycine receptor antagonist;
neurotransmitter agent;
rodenticide
quinidine[no description available]medium20cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
cocaine[no description available]medium30benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
rauwolscine[no description available]medium20methyl 17-hydroxy-20xi-yohimban-16-carboxylate
chlorprothixene[no description available]medium10chlorprothixene
flunarizine[no description available]medium20diarylmethane
thiothixene[no description available]medium20N-methylpiperazineanticoronaviral agent
cinnarizine[no description available]medium40diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
quinine[no description available]medium20cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic
codeine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
morphine[no description available]medium190morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
levorphanol[no description available]medium10morphinane alkaloid
dextrorphan[no description available]medium10morphinane alkaloid
zimeldine[no description available]medium10styrenes
1-methyl-d-lysergic acid butanolamide[no description available]medium20ergot alkaloid;
monocarboxylic acid amide		serotonergic antagonist;
sympatholytic agent;
vasoconstrictor agent
scopolamine hydrobromide[no description available]medium20
n(6)-benzyladenosine[no description available]medium60
1,3-dipropyl-8-(4-sulfophenyl)xanthine[no description available]medium90
bw a1433u[no description available]medium10
1,3-dipropyl-8-phenylxanthine[no description available]medium10oxopurine
1-isoamyl-3-isobutylxanthine[no description available]medium10
1,3-dipropylxanthine[no description available]medium30
8-bromoadenosine[no description available]medium30purine nucleoside
n-methyladenosine[no description available]medium50methyladenosine
5'-methylthioadenosine[no description available]medium20thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
n-cyclopropyl adenosine-5'-carboxamide[no description available]medium50
9-xylosyladenine[no description available]medium20purine nucleoside
3-deazaadenosine[no description available]medium10
tubercidin[no description available]medium90antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
ribonucleoside		antimetabolite;
antineoplastic agent;
bacterial metabolite
2'-deoxyadenosine[no description available]medium70purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
hyaluronoglucosaminidase[no description available]medium10purine nucleoside
vidarabine[no description available]high221beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
bacterial metabolite;
nucleoside antibiotic
vidarabine[no description available]high220beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
bacterial metabolite;
nucleoside antibiotic
3-deazaadenosine[no description available]medium50
aristeromycin[no description available]medium20
metrifudil[no description available]medium30
8-aminoadenosine[no description available]medium30
2'-o-methyladenosine[no description available]medium20adenosines;
ether		fungal metabolite
n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine[no description available]medium80adenosines;
monocarboxylic acid amide;
organoiodine compound		adenosine A3 receptor agonist
5'-noraristeromycin[no description available]medium10
2-hexynyladenosine-5'-n-ethylcarboxamide[no description available]medium20
5'-deoxyadenosine[no description available]medium105'-deoxyribonucleoside;
adenosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
3'-c-methyladenosine[no description available]medium30
1-aminoadenosine[no description available]medium20
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamide[no description available]medium60
3-iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine[no description available]medium20adenosines;
monocarboxylic acid amide;
organoiodine compound
8-(3-chlorostyryl)caffeine[no description available]medium60monochlorobenzenes;
trimethylxanthine		adenosine A2A receptor antagonist;
EC 1.4.3.4 (monoamine oxidase) inhibitor
gamma-aminobutyric acid[no description available]medium130amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
5-methoxytryptamine[no description available]medium10aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist
clonazepam[no description available]medium301,4-benzodiazepinone;
monochlorobenzenes		anticonvulsant;
anxiolytic drug;
GABA modulator
fluoxetine[no description available]medium10(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound
flurazepam[no description available]medium201,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
tertiary amino compound		anticonvulsant;
anxiolytic drug;
GABAA receptor agonist;
sedative
ketanserin[no description available]medium10aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
muscimol[no description available]medium10alkaloid;
isoxazoles;
primary amino compound		fungal metabolite;
GABA agonist;
oneirogen;
psychotropic drug
nomifensine[no description available]medium10isoquinolinesdopamine uptake inhibitor
lysergic acid diethylamide[no description available]medium10ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
phencyclidine[no description available]medium20benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
kainic acid[no description available]medium50dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
n-methylaspartate[no description available]medium50amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
phorbol 12,13-dibutyrate[no description available]medium70butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone
D-alanine[no description available]medium10alanine zwitterion;
alanine;
D-alpha-amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite
nicotine[no description available]medium203-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
5'-n-methylcarboxamideadenosine[no description available]medium60
tert-butylbicyclophosphorothionate[no description available]medium10organic thiophosphate
methoctramine[no description available]medium40hydrochloridemuscarinic antagonist
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid[no description available]medium10
leukotriene b4[no description available]medium30dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
leukotriene d4[no description available]medium10dipeptide;
leukotriene;
organic sulfide		bronchoconstrictor agent;
human metabolite;
mouse metabolite
triprolidine[no description available]medium10N-alkylpyrrolidine;
olefinic compound;
pyridines		H1-receptor antagonist
naloxone[no description available]medium50morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
u-44619[no description available]medium20
2'-c-methyladenosine[no description available]medium20
1-deazaadenosine[no description available]medium20
2-chloro-2',3'-dideoxyadenosine[no description available]medium20
apnea[no description available]medium10purine nucleoside
sch 58261[no description available]medium30triazolopyrimidines
1,3-diethyl-8-phenylxanthine[no description available]medium60
bw a522[no description available]medium10
zm 241385[no description available]medium50diamino-1,3,5-triazine
bw a1433[no description available]medium10
2-(2-(4-chlorophenyl)ethoxy)adenosine[no description available]medium20
3'-amino-3'-deoxyadenosine[no description available]medium10
2'-amino-2'-deoxyadenosine[no description available]medium10
5'-amino-5'-deoxyadenosine[no description available]medium20
vuf 8504[no description available]medium10
2-fluoroadenosine[no description available]medium30adenosines;
organofluorine compound
mrs 1220[no description available]medium10quinazolines
mrs 1523[no description available]medium30
acetamide[no description available]medium10acetamides;
carboximidic acid;
monocarboxylic acid amide;
N-acylammonia
catechol[no description available]medium20catecholsallelochemical;
genotoxin;
plant metabolite
taxifolin[no description available]medium203'-hydroxyflavanones;
4'-hydroxyflavanones;
dihydroflavonols;
pentahydroxyflavanone;
secondary alpha-hydroxy ketone
phosphonoacetic acid[no description available]medium30monocarboxylic acid;
phosphonic acids		antiviral agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
3,4-dihydroxyphenylacetic acid[no description available]medium40catechols;
dihydroxyphenylacetic acid		human metabolite
aminocaproic acid[no description available]medium10amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite
diacetyl[no description available]medium10alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite
hydroquinone[no description available]medium20benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
melatonin[no description available]medium30acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
n-acetylserotonin[no description available]medium10acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist
pyrazinamide[no description available]medium20monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
taurine[no description available]medium20amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
2-amino-5-phosphonovalerate[no description available]medium40non-proteinogenic alpha-amino acidNMDA receptor antagonist
alpha-methyl-4-carboxyphenylglycine[no description available]medium10
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid[no description available]medium10
1-hydroxy-3-amino-2-pyrrolidone[no description available]medium10
ibotenic acid[no description available]medium10non-proteinogenic alpha-amino acidneurotoxin
n(8)-bromoacetyl-n(1)-3'-(4-indolyloxy)-2'-hydroxypropyl-1,8-diamino-4-menthane[no description available]medium10
sk&f-38393[no description available]medium30benzazepine;
catechols;
secondary amino compound
vanilmandelic acid[no description available]medium102-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite
1,10-diaminodecane[no description available]medium20
1,5-dihydroxyisoquinoline[no description available]medium10isoquinolinolEC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
pk 11195[no description available]medium30aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent
1-(2-trifluoromethylphenyl)imidazole[no description available]medium10imidazoles
1-aminobenzotriazole[no description available]medium20
1-methylimidazole[no description available]medium10imidazoles
edelfosine[no description available]medium10glycerophosphocholine
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one[no description available]medium30oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor
2,2'-dipyridyl[no description available]medium30bipyridinechelator;
ferroptosis inhibitor
2-hydroxysaclofen[no description available]medium10organochlorine compound
3,4-dichloroisocoumarin[no description available]medium20isocoumarins;
organochlorine compound		geroprotector;
serine protease inhibitor
phaclofen[no description available]medium10organophosphate oxoanion;
zwitterion
3-aminobenzamide[no description available]medium10benzamides;
substituted aniline		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
3-bromo-7-nitroindazole[no description available]medium10
enprofylline[no description available]medium60oxopurineanti-arrhythmia drug;
anti-asthmatic drug;
bronchodilator agent;
non-steroidal anti-inflammatory drug
3-nitropropionic acid[no description available]medium30C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin
4-amino-1,8-naphthalimide[no description available]medium20benzoisoquinoline;
dicarboximide
homovanillic acid[no description available]medium30guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
4-hydroxybenzoic acid hydrazide[no description available]medium10carbohydrazide;
phenols
4-phenyl-3-furoxancarbonitrile[no description available]medium201,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
5,5-dimethyl-1-pyrroline-1-oxide[no description available]medium201-pyrroline nitronesneuroprotective agent;
spin trapping reagent
5,7-dichlorokynurenic acid[no description available]medium10quinolines
5-(n,n-hexamethylene)amiloride[no description available]medium20aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker
ethylisopropylamiloride[no description available]medium20aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker
5-fluoroindole-2-carboxylic acid[no description available]medium30indolyl carboxylic acid
hydroxyindoleacetic acid[no description available]medium10indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
phenanthridone[no description available]medium20lactam;
phenanthridines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
immunosuppressive agent;
mutagen
6-chloromelatonin[no description available]medium10acetamides
6-hydroxymelatonin[no description available]medium10acetamides;
tryptamines		metabolite;
mouse metabolite
6-methoxytryptoline[no description available]medium10
6-nitroso-1,2-benzopyrone[no description available]medium20
7-chlorokynurenic acid[no description available]medium10organochlorine compound;
quinolinemonocarboxylic acid		neuroprotective agent;
NMDA receptor antagonist
7-nitroindazole[no description available]medium20
acetazolamide[no description available]medium20monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
acetohexamide[no description available]medium10acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
ag 127[no description available]medium20nitrophenol
rtki cpd[no description available]medium20aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector
tyrphostin a23[no description available]medium20catechols
tyrphostin 25[no description available]medium20benzenetriol
tyrphostin a1[no description available]medium10methoxybenzenesgeroprotector
1-aminoindan-1,5-dicarboxylic acid[no description available]medium10
albuterol[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
alpha-methyltyrosine methyl ester[no description available]medium10
altretamine[no description available]medium20triamino-1,3,5-triazine
amfonelic acid[no description available]medium10
amifostine anhydrous[no description available]medium10diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent
amoxapine[no description available]medium30dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor
aniracetam[no description available]medium20N-acylpyrrolidine;
pyrrolidin-2-ones
2-amino-4-phosphonobutyric acid[no description available]medium20
aspirin[no description available]medium30benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
atenolol[no description available]medium20ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic
alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate[no description available]medium10alpha-amino acid
aurintricarboxylic acid[no description available]medium20monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist
azathioprine[no description available]medium20aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug
azelaic acid[no description available]medium20alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		antibacterial agent;
antineoplastic agent;
dermatologic drug;
plant metabolite
bay-k-8644[no description available]medium80(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
benzamide[no description available]medium10benzamides
bml 190[no description available]medium20N-acylindole
brimonidine[no description available]medium30imidazoles;
quinoxaline derivative;
secondary amine		adrenergic agonist;
alpha-adrenergic agonist;
antihypertensive agent
bumetanide[no description available]medium50amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
carbetapentane[no description available]medium10benzenes
carisoprodol[no description available]medium20carbamate estermuscle relaxant
carmustine[no description available]medium10N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
cgs 12066[no description available]medium10N-arylpiperazine;
organofluorine compound;
pyrroloquinoxaline		serotonergic agonist
chlorambucil[no description available]medium70aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
chlorambucil[no description available]medium71aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
chlormezanone[no description available]medium101,3-thiazine;
lactam;
monochlorobenzenes;
sulfone		antipsychotic agent;
anxiolytic drug;
muscle relaxant
chlorothiazide[no description available]medium10benzothiadiazineantihypertensive agent;
diuretic
chlorpropamide[no description available]medium20monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
chlorzoxazone[no description available]medium201,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound		muscle relaxant;
sedative
cilostamide[no description available]medium20quinolines
cilostazol[no description available]medium50lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
cilostazol[no description available]medium51lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
cinoxacin[no description available]medium30cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent
ciprofibrate[no description available]medium10cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
clofibrate[no description available]medium10aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
clotrimazole[no description available]medium20conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
cx546[no description available]medium10
cyclothiazide[no description available]medium10benzothiadiazineantihypertensive agent;
diuretic
dephostatin[no description available]medium10
nonivamide[no description available]medium10capsaicinoid;
phenols		lachrymator
r 59022[no description available]medium10diarylmethane
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
diphenyleneiodonium[no description available]medium10organic cation
disopyramide[no description available]medium10monocarboxylic acid amide;
pyridines;
tertiary amino compound		anti-arrhythmia drug
disulfiram[no description available]medium30organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
2-amino-7-phosphonoheptanoic acid[no description available]medium20
thiorphan[no description available]medium10N-acyl-amino acid
2,3-dimethoxy-1,4-naphthoquinone[no description available]medium201,4-naphthoquinones
domperidone[no description available]medium30benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
ebselen[no description available]medium30benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger
ellipticine[no description available]medium30indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite
emodin[no description available]medium20trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor
ethosuximide[no description available]medium10dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker
etodolac[no description available]medium20monocarboxylic acid;
organic heterotricyclic compound		antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
felbamate[no description available]medium20carbamate esteranticonvulsant;
neuroprotective agent
fenofibrate[no description available]medium30aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
fluorouracil[no description available]medium40nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
fluspirilene[no description available]medium20diarylmethane
flutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent
formoterol fumarate[no description available]medium20formamides;
phenols;
phenylethanolamines;
secondary alcohol;
secondary amino compound
fpl 64176[no description available]medium20carboxylic ester;
pyrroles		calcium channel agonist
furafylline[no description available]medium10oxopurine
furosemide[no description available]medium20chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
fusaric acid[no description available]medium10aromatic carboxylic acid;
pyridines
gabapentin[no description available]medium10gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
4-amino-5-hexynoic acid[no description available]medium10
glipizide[no description available]medium20aromatic amide;
monocarboxylic acid amide;
N-sulfonylurea;
pyrazines		EC 2.7.1.33 (pantothenate kinase) inhibitor;
hypoglycemic agent;
insulin secretagogue
glyburide[no description available]medium100monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
1-(5-isoquinolinesulfonyl)piperazine[no description available]medium10isoquinolines
hemicholinium 3[no description available]medium10morpholines
4-fluorohexahydrosiladifenidol[no description available]medium10
hydrochlorothiazide[no description available]medium20benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
hydroxyurea[no description available]medium10one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
ibudilast[no description available]medium10pyrazolopyridine
ibuprofen[no description available]medium20monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
ic 261[no description available]medium20indoles
ifenprodil[no description available]medium10piperidines
indirubin-3'-monoxime[no description available]medium20
iodoacetamide[no description available]medium10
4-piperidinecarboxylic acid[no description available]medium20
4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline[no description available]medium10
jl 18[no description available]medium20
nsc 664704[no description available]medium20indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector
ketoconazole[no description available]medium20dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
ketoprofen[no description available]medium20benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
kynurenic acid[no description available]medium40monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
2-amino-3-phosphonopropionic acid[no description available]medium10alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist
lamotrigine[no description available]medium201,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic
lansoprazole[no description available]medium30benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
beta-lapachone[no description available]medium20benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite
leflunomide[no description available]medium20(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor
linopirdine[no description available]medium20indoles
loratadine[no description available]medium30benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist
loxoprofen[no description available]medium10cyclopentanones;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one[no description available]medium10chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
meclofenamate sodium anhydrous[no description available]medium20organic sodium salt
methiothepin[no description available]medium20aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist
methoctramine[no description available]medium10aromatic ether;
tetramine		muscarinic antagonist
nocodazole[no description available]medium20aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
3-Hydroxy-alpha-methyl-DL-tyrosine[no description available]medium10benzenes;
monocarboxylic acid
metolazone[no description available]medium20organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor
milrinone[no description available]medium10bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
minoxidil[no description available]medium20dialkylarylamine;
tertiary amino compound
mitotane[no description available]medium10diarylmethane
mitoxantrone[no description available]medium30dihydroxyanthraquinoneanalgesic;
antineoplastic agent
ml 7[no description available]medium20N-sulfonyldiazepane;
organoiodine compound		EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide[no description available]medium10naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide
n-bromoacetamide[no description available]medium10
ethylmaleimide[no description available]medium90maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
fg 7142[no description available]medium20beta-carbolines
fenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		membrane transport modulator
n 0840[no description available]medium20
nialamide[no description available]medium30organonitrogen compound;
organooxygen compound
niclosamide[no description available]medium20benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
niflumic acid[no description available]medium30aromatic carboxylic acid;
pyridines
nilutamide[no description available]medium10(trifluoromethyl)benzenes;
C-nitro compound;
imidazolidinone		androgen antagonist;
antineoplastic agent
nimesulide[no description available]medium20aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
nimodipine[no description available]medium302-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nipecotic acid[no description available]medium10beta-amino acid;
piperidinemonocarboxylic acid
masoprocol[no description available]medium20catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite
5-nitro-2-(3-phenylpropylamino)benzoic acid[no description available]medium30nitrobenzoic acid
ns 2028[no description available]medium10
ns 1619[no description available]medium30(trifluoromethyl)benzenes;
benzimidazoles;
phenols		potassium channel opener
o(6)-benzylguanine[no description available]medium10
ofloxacin[no description available]medium303-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline
olomoucine[no description available]medium202,6-diaminopurines;
ethanolamines		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
oxaprozin[no description available]medium201,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug
oxatomide[no description available]medium20benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist
oxiracetam[no description available]medium10organonitrogen compound;
organooxygen compound
oxolinic acid[no description available]medium10aromatic carboxylic acid;
organic heterotricyclic compound;
oxacycle;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antifungal agent;
antiinfective agent;
antimicrobial agent;
enzyme inhibitor
quinone[no description available]medium101,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite
fenclonine[no description available]medium10phenylalanine derivative
palmidrol[no description available]medium20endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent
1,7-dimethylxanthine[no description available]medium10dimethylxanthinecentral nervous system stimulant;
human blood serum metabolite;
human xenobiotic metabolite;
mouse metabolite
pd 98059[no description available]medium20aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
pentamidine[no description available]medium10aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
pentoxifylline[no description available]medium40oxopurine
perphenazine[no description available]medium30N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
phenyl biguanide[no description available]medium20guanidinescentral nervous system drug
phenylbutazone[no description available]medium30pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
phloretin[no description available]medium20dihydrochalconesantineoplastic agent;
plant metabolite
picotamide[no description available]medium20benzamides
pinacidil[no description available]medium40pyridines
pindolol[no description available]medium10indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
piperidine-4-sulfonic acid[no description available]medium10
piracetam[no description available]medium20organonitrogen compound;
organooxygen compound
pirenperone[no description available]medium30aromatic ketone
praziquantel[no description available]medium30isoquinolines
primidone[no description available]medium20pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
proglumide[no description available]medium10benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
propentofylline[no description available]medium40oxopurine
propofol[no description available]medium20phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
pf 5901[no description available]medium30quinolines
riluzole[no description available]medium30benzothiazoles
risperidone[no description available]medium201,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
ritanserin[no description available]medium30organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
salmeterol xinafoate[no description available]medium10ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound
sb 202190[no description available]medium20imidazoles;
organofluorine compound;
phenols;
pyridines		apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sobuzoxane[no description available]medium10organic molecular entity
spiroxatrine[no description available]medium20imidazolidines
sq 22536[no description available]medium10nucleoside analogue;
oxolanes		EC 4.6.1.1 (adenylate cyclase) inhibitor
sulfaphenazole[no description available]medium10primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor
sulpiride[no description available]medium10benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
t0156[no description available]medium20naphthyridine derivative
1,4-bis(2-(3,5-dichloropyridyloxy))benzene[no description available]medium10
terfenadine[no description available]medium30diarylmethane
tetraisopropylpyrophosphamide[no description available]medium20phosphoramide
thalidomide[no description available]medium10phthalimides;
piperidones
theobromine[no description available]medium70dimethylxanthineadenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate[no description available]medium30trihydroxybenzoic acid
tolazamide[no description available]medium20N-sulfonylureahypoglycemic agent;
potassium channel blocker
tolbutamide[no description available]medium20N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid[no description available]medium10
ici 136,753[no description available]medium20pyrazolopyridine
triamterene[no description available]medium20pteridinesdiuretic;
sodium channel blocker
trimethoprim[no description available]medium30aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
tropicamide[no description available]medium10acetamides
tyrphostin a9[no description available]medium20alkylbenzenegeroprotector
vigabatrin[no description available]medium10gamma-amino acidanticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole[no description available]medium20aromatic primary alcohol;
furans;
indazoles		antineoplastic agent;
apoptosis inducer;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
zardaverine[no description available]medium10organofluorine compound;
pyridazinone		anti-asthmatic drug;
bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
peripheral nervous system drug
cortisone acetate[no description available]medium10corticosteroid hormone
corticosterone[no description available]medium3011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
procaine hydrochloride[no description available]medium10organic molecular entity
isoproterenol hydrochloride[no description available]medium20catechols
histamine dihydrochloride[no description available]medium10
carbachol[no description available]medium190ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
spironolactone[no description available]medium203-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
estrone[no description available]medium3017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
androsterone[no description available]medium3017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
promazine hydrochloride[no description available]medium30hydrochloride
pilocarpine hydrochloride[no description available]medium20hydrochloride
dimethylphenylpiperazinium iodide[no description available]medium50N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
pentylenetetrazole[no description available]medium50organic heterobicyclic compound;
organonitrogen heterocyclic compound
racepinephrine hydrochloride[no description available]medium20
(4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride[no description available]medium20
hexamethonium bromide[no description available]medium10
cystamine dihydrochloride[no description available]medium10
cantharidin[no description available]medium20cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide
aspartic acid[no description available]medium40aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
glutamine[no description available]medium10amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
vincristine[no description available]medium10acetate ester;
formamides;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
physostigmine[no description available]medium20carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
apomorphine[no description available]medium30aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
promethazine hydrochloride[no description available]medium30hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative
bromodeoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
levodopa[no description available]medium20amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
methoxamine hydrochloride[no description available]medium30dimethoxybenzene
papaverine hydrochloride[no description available]medium30
bretylium tosylate[no description available]medium40organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent
berlition[no description available]medium10dithiolanes;
heterocyclic fatty acid;
lipoic acid;
thia fatty acid		cofactor;
nutraceutical;
prosthetic group
methacholine chloride[no description available]medium30quaternary ammonium salt
androstenedione[no description available]medium3017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
colchicine[no description available]medium30alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
yohimbine hydrochloride[no description available]medium20
gallamine triethiodide[no description available]medium10
cycloheximide[no description available]medium70antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
egtazic acid[no description available]medium40diether;
tertiary amino compound;
tetracarboxylic acid		chelator
cycloserine[no description available]medium104-amino-1,2-oxazolidin-3-one;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic;
zwitterion		antiinfective agent;
antimetabolite;
antitubercular agent;
metabolite;
NMDA receptor agonist
17-alpha-hydroxyprogesterone[no description available]medium3017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin
quinacrine monohydrochloride[no description available]medium20
chlorpromazine hydrochloride[no description available]medium30hydrochloride;
phenothiazines		anticoronaviral agent;
phenothiazine antipsychotic drug
cytarabine hydrochloride[no description available]medium20
tryptophan[no description available]medium20erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
lidocaine hydrochloride[no description available]medium30hydrochlorideanti-arrhythmia drug;
local anaesthetic
arginine[no description available]medium90arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
rotenone[no description available]medium20organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin
synephrine[no description available]medium10ethanolamines;
phenethylamine alkaloid;
phenols		alpha-adrenergic agonist;
plant metabolite
pyridostigmine bromide[no description available]medium30pyridinium salt
imipramine hydrochloride[no description available]medium30hydrochlorideantidepressant
neostigmine bromide[no description available]medium20bromide salt
edrophonium chloride[no description available]medium20chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
suramin sodium[no description available]medium20organic sodium saltangiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
pyrazolanthrone[no description available]medium20anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
methapyrilene hydrochloride[no description available]medium30hydrochlorideanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative
tetrracaine hydrochloride[no description available]medium20benzoate ester
chelidamic acid[no description available]medium10
diphenhydramine hydrochloride[no description available]medium30hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
cysteamine hydrochloride[no description available]medium10
propantheline bromide[no description available]medium30xanthenes
hydralazine hydrochloride[no description available]medium10hydrochlorideantihypertensive agent;
vasodilator agent
ethamivan[no description available]medium20methoxybenzenes;
phenols
pargyline hydrochloride[no description available]medium30
aminophylline[no description available]medium100mixturebronchodilator agent;
cardiotonic drug
azacitidine[no description available]medium30N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
azacitidine[no description available]medium31N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
orphenadrine hydrochloride[no description available]medium30hydrochlorideantiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
betamethasone[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent
benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide[no description available]medium20
cyproterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin
podophyllotoxin[no description available]medium30furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
tetrahydrozoline hydrochloride[no description available]medium30hydrochloridenasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
dequalinium chloride[no description available]medium20organic chloride saltantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor
decamethonium dibromide[no description available]medium20
amitriptyline hydrochloride[no description available]medium30organic tricyclic compound
naphazoline hydrochloride[no description available]medium30organic molecular entity
doxylamine succinate[no description available]medium30organic molecular entity
carbamylhydrazine monohydrochloride[no description available]medium10organic molecular entity
formestane[no description available]medium3017-oxo steroid;
3-oxo-Delta(4) steroid;
enol;
hydroxy steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
debrisoquin sulfate[no description available]medium10organic sulfate salt
betaine hydrochloride[no description available]medium10
bethanechol chloride[no description available]medium20carbamate ester;
chloride salt;
quaternary ammonium salt		muscarinic agonist
acetylcysteine[no description available]medium30acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
Mecamylamine hydrochloride[no description available]medium20monoterpenoid
vinblastine[no description available]medium10
cyproheptadine hydrochloride (anhydrous)[no description available]medium30hydrochloride
5 alpha-androstane-3 alpha,17 beta-diol[no description available]medium20androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite
pimozide[no description available]medium30benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
azetidyl-2-carboxylic acid[no description available]medium10azetidine-2-carboxylic acid
muscarine[no description available]medium10
antazoline hydrochloride[no description available]medium30
doxifluridine[no description available]medium10organofluorine compound;
pyrimidine 5'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
prodrug
meclofenoxate hydrochloride[no description available]medium10
clonidine hydrochloride[no description available]medium10dichlorobenzene
beclomethasone[no description available]medium3011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug
buthionine sulfoximine[no description available]medium30diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
mexiletine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
cyclophosphamide[no description available]medium10hydratealkylating agent;
antineoplastic agent;
carcinogenic agent;
immunosuppressive agent
suxamethonium chloride[no description available]medium10chloride saltmuscle relaxant
cyclobenzaprine hydrochloride[no description available]medium20hydrochlorideantidepressant;
muscle relaxant
metoclopramide hydrochloride[no description available]medium30
isoetharine mesylate[no description available]medium30
zalcitabine[no description available]medium10pyrimidine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
propionylpromazine hydrochloride[no description available]medium20
camptothecin[no description available]medium20delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
nsc-145,668[no description available]medium10hydrochlorideantimetabolite;
antineoplastic agent
clodronic acid[no description available]medium101,1-bis(phosphonic acid);
one-carbon compound;
organochlorine compound		antineoplastic agent;
bone density conservation agent
benserazide hydrochloride[no description available]medium30hydrochlorideantiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
pancuronium bromide[no description available]medium20bromide saltcholinergic antagonist;
muscle relaxant;
nicotinic antagonist
tetradecanoylphorbol acetate[no description available]medium130acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
danazol[no description available]medium2017beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector
metergoline[no description available]medium30carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist
lisuride[no description available]medium10monocarboxylic acid amideantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
serotonergic agonist
disopyramide phosphate[no description available]medium20organoammonium phosphate
bromocriptine[no description available]medium10indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist
ergocristine[no description available]medium10ergot alkaloid
triamcinolone[no description available]medium1011beta-hydroxy steroid;
16alpha-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
zidovudine[no description available]medium30azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
paclitaxel[no description available]medium20taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
buspirone hydrochloride[no description available]medium30hydrochlorideanxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
etoposide[no description available]medium40beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
etoposide[no description available]medium41beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
propafenone hydrochloride[no description available]medium30hydrochlorideanti-arrhythmia drug
etazolate hydrochloride[no description available]medium20
butaclamol[no description available]medium10amino alcohol;
organic heteropentacyclic compound;
tertiary alcohol;
tertiary amino compound		dopaminergic antagonist
ribavirin[no description available]medium301-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
carbidopa[no description available]medium20catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
cephradine[no description available]medium10beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug
methyldopa[no description available]medium10L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
lonidamine[no description available]medium10dichlorobenzene;
indazoles;
monocarboxylic acid		antineoplastic agent;
antispermatogenic agent;
EC 2.7.1.1 (hexokinase) inhibitor;
geroprotector
dexibuprofen[no description available]medium10ibuprofennon-narcotic analgesic;
non-steroidal anti-inflammatory drug
quisqualic acid[no description available]medium20non-proteinogenic alpha-amino acid
pirfenidone[no description available]medium10pyridoneantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
flecainide acetate[no description available]medium30acetate saltanti-arrhythmia drug
nicardipine hydrochloride[no description available]medium30dihydropyridinegeroprotector
idarubicin[no description available]medium30anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
captopril[no description available]medium20alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
terazosin hydrochloride anhydrous[no description available]medium30
pergolide mesylate[no description available]medium30methanesulfonate saltantiparkinson drug;
dopamine agonist;
geroprotector
ranitidine hydrochloride[no description available]medium10
cefaclor anhydrous[no description available]medium10cephalosporinantibacterial drug;
drug allergen
alo 2145[no description available]medium10hydrochloridealpha-adrenergic agonist;
antiglaucoma drug
enoximone[no description available]medium10aromatic ketone
atomoxetine[no description available]medium20aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
raloxifene hydrochloride[no description available]medium20hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
mifepristone[no description available]medium303-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive
quinpirole hydrochloride[no description available]medium10
imazodan[no description available]medium10
mibefradil dihydrochloride[no description available]medium20
aptiganel hydrochloride[no description available]medium20
phenelzine sulfate[no description available]medium20organic molecular entity
fluoxetine hydrochloride[no description available]medium30hydrochloride;
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
propranolol hydrochloride[no description available]medium20hydrochloride
bupropion hydrochloride[no description available]medium20aromatic ketone
diltiazem hydrochloride[no description available]medium20hydrochlorideantihypertensive agent;
calcium channel blocker;
vasodilator agent
trazodone hydrochloride[no description available]medium30hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
verapamil hydrochloride[no description available]medium30
doxazosin mesylate[no description available]medium30methanesulfonate saltgeroprotector
terfenadine[no description available]medium20diarylmethane
amantadine hydrochloride[no description available]medium30hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist
mevastatin[no description available]medium102-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite
chloroquine diphosphate[no description available]medium20
dobutamine hydrochloride[no description available]medium20hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
desipramine hydrochloride[no description available]medium30hydrochloridedrug allergen
dopamine hydrochloride[no description available]medium30catecholamine
proadifen hydrochloride[no description available]medium20
4-nitrobenzylthioinosine[no description available]medium160purine nucleoside
rutecarpine[no description available]medium20beta-carbolines
trihexyphenidyl hydrochloride[no description available]medium30aralkylamine
thioridazine hydrochloride[no description available]medium30hydrochloridefirst generation antipsychotic;
geroprotector
procainamide hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
siquil[no description available]medium30hydrochlorideanticoronaviral agent
sotalol hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug;
beta-adrenergic antagonist
oxymetazoline hydrochloride[no description available]medium30hydrochloridealpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
alprenolol hydrochloride[no description available]medium30hydrochloride
2-methoxyestradiol[no description available]medium3017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
fluphenazine hydrochloride[no description available]medium20phenothiazinesanticoronaviral agent
tryptamine monohydrochloride[no description available]medium20
clomipramine hydrochloride[no description available]medium30hydrochlorideanticoronaviral agent;
antidepressant;
serotonergic antagonist;
serotonergic drug
amiloride hydrochloride[no description available]medium20hydratediuretic;
sodium channel blocker
prazosin hydrochloride[no description available]medium30hydrochloride
mianserin hydrochloride[no description available]medium30hydrochloridegeroprotector
lomefloxacin hydrochloride[no description available]medium20hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent
fenspiride hydrochloride[no description available]medium20
nilverm[no description available]medium20organic molecular entity
sanguinarine chloride[no description available]medium20
ropinirole hydrochloride[no description available]medium20indoles
plasmenylserine[no description available]medium10O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5-aminovaleric acid hydrochloride[no description available]medium10
n-acetyltryptamine[no description available]medium10acetamides;
indoles
D-serine[no description available]medium10D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist
dihydroergotamine mesylate[no description available]medium20methanesulfonate saltnon-narcotic analgesic;
serotonergic agonist;
vasoconstrictor agent
ranolazine hydrochloride[no description available]medium20
loxapine succinate[no description available]medium30succinate saltgeroprotector
guanfacine hydrochloride[no description available]medium30acetamidesgeroprotector
pirenzepine dihydrochloride[no description available]medium10hydrochloride
labetalol hydrochloride[no description available]medium30salicylamides
acecainide hydrochloride[no description available]medium20
loperamide hydrochloride[no description available]medium30hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
maprotiline hydrochloride[no description available]medium30anthracenes
protoporphyrin ix, disodium salt[no description available]medium10
siguazodan[no description available]medium10pyridazinone
3-octadecanamido-2-ethoxypropylphosphocholine[no description available]medium10
chelerythrine chloride[no description available]medium20
tosyllysine chloromethyl ketone[no description available]medium20
5-(n-methyl-n-isobutyl)amiloride[no description available]medium20
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride[no description available]medium20hydrochlorideEC 2.7.11.13 (protein kinase C) inhibitor
amperozide hydrochloride[no description available]medium20hydrochlorideanxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist
pyrrolidine dithiocarbamic acid[no description available]medium20
agroclavine[no description available]medium10ergot alkaloid
s-methylisothiourea sulfate[no description available]medium10
p-Aminobenzamidine dihydrochloride[no description available]medium20organic molecular entity
benzamidine hydrochloride[no description available]medium10
ketorolac tromethamine[no description available]medium10organoammonium saltanalgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor
methionine sulfoximine[no description available]medium10L-alpha-amino acid zwitterion;
L-methionine derivative;
methionine sulfoximine;
non-proteinogenic L-alpha-amino acid		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
geroprotector
tretazicar[no description available]medium10
carbetapentane citrate[no description available]medium20carbonyl compound
phentolamine mesylate[no description available]medium30
mephentermine[no description available]medium202-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite
oxybutynin hydrochloride[no description available]medium30hydrochloride
nimustine[no description available]medium10hydrochlorideantineoplastic agent
cordium[no description available]medium10hydrate;
hydrochloride
L-2-aminoadipic acid[no description available]medium102-aminoadipic acidEscherichia coli metabolite;
human metabolite
prilocaine hydrochloride[no description available]medium30hydrochloridelocal anaesthetic
mor-14[no description available]medium10hydroxypiperidine;
piperidine alkaloid;
tertiary amino compound		anti-HIV agent;
cardioprotective agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
plant metabolite
brexanolone[no description available]medium203-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative
hexamethonium chloride[no description available]medium10
6-(4-nitrobenzylthio)guanosine[no description available]medium40
3-aminopropylphosphonic acid[no description available]medium10phosphonic acids;
primary amino compound;
zwitterion		GABAB receptor agonist
zpck[no description available]medium20
tetrahydrodeoxycorticosterone[no description available]medium2021-hydroxy steroid
mizoribine[no description available]medium40imidazolesanticoronaviral agent
1-amino-1,3-dicarboxycyclopentane[no description available]medium40
u 73122[no description available]medium10aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
alphaxalone[no description available]medium20corticosteroid hormone
s-nitrosoglutathione[no description available]medium10glutathione derivative;
nitrosothio compound		bronchodilator agent;
nitric oxide donor;
platelet aggregation inhibitor;
signalling molecule
cp-55,940[no description available]medium20
vanoxerine[no description available]medium20hydrochloridedopamine uptake inhibitor
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate[no description available]medium30beta-carbolines
u 69593[no description available]medium20monocarboxylic acid amide;
N-alkylpyrrolidine;
organic heterobicyclic compound;
oxaspiro compound		anti-inflammatory agent;
diuretic;
kappa-opioid receptor agonist
cv 3988[no description available]medium20
beta-carboline-3-carboxylic acid methyl ester[no description available]medium30beta-carbolines
hypotaurine[no description available]medium10aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite
dihydrokainate[no description available]medium10dicarboxylic acid
gabazine[no description available]medium10
cl 218872[no description available]medium10pyridazines;
ring assembly
betaxolol hydrochloride[no description available]medium30hydrochlorideantihypertensive agent;
beta-adrenergic antagonist
catechin[no description available]medium10hydrategeroprotector
1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine[no description available]medium20hydrobromideserotonergic antagonist
s-methylthiocitrulline[no description available]medium10imidothiocarbamic ester;
L-arginine derivative;
L-ornithine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
neuroprotective agent
dihydrocapsaicin[no description available]medium10capsaicinoid
ml 9[no description available]medium10
parthenolide[no description available]medium20germacranolide
3',4'-dichlorobenzamil[no description available]medium20guanidines;
pyrazines
1-(carboxymethylthio)tetradecane[no description available]medium10straight-chain fatty acid
2-iodomelatonin[no description available]medium10acetamides
arcaine, sulfate[no description available]medium10
gr 113808[no description available]medium20indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist
gallopamil hydrochloride[no description available]medium30
gamma-glutamylaminomethylsulfonic acid[no description available]medium10
buthionine sulfoximine[no description available]medium202-amino-4-(S-butylsulfonimidoyl)butanoic acidEC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
sb 204070a[no description available]medium20
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine[no description available]medium20(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist
l 655240[no description available]medium10methylindole
san 58035[no description available]medium20
nnc 711[no description available]medium10
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide[no description available]medium20diarylmethane
e 64[no description available]medium20dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor
azetidine-2,4-dicarboxylic acid[no description available]medium10
pre 084[no description available]medium20morpholines
methotrexate[no description available]medium60dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol[no description available]medium20
sr 2640[no description available]medium20quinolines
ici 204448[no description available]medium10
4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride[no description available]medium10
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide[no description available]medium20phenylindole
3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan[no description available]medium10
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine[no description available]medium20
l 741626[no description available]medium20piperidines
nisoxetine hydrochloride[no description available]medium20
ng-nitroarginine methyl ester[no description available]medium10hydrochlorideEC 1.14.13.39 (nitric oxide synthase) inhibitor
tilarginine acetate[no description available]medium10
alpha-guanidinoglutaric acid[no description available]medium10L-glutamic acid derivative
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomer[no description available]medium30
imidazole-4-acetic acid hydrochloride[no description available]medium10
nsc-141549[no description available]medium20
2-chloro-2-deoxyglucose[no description available]medium10
idazoxan hydrochloride[no description available]medium30
isoguvacine hydrochloride[no description available]medium10
8-methoxymethyl-3-isobutyl-1-methylxanthine[no description available]medium10oxopurine
cyc 202[no description available]medium202,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
Serotonin hydrochloride[no description available]medium10tryptamines
n-phthaloylglutamic acid[no description available]medium10L-glutamic acid derivative;
phthalimides
1,3-dipropyl-7-methylxanthine[no description available]medium10
ag 3-5[no description available]medium10C-nitro compound
n-n-propylnorapomorphine[no description available]medium10aporphine alkaloid
urapidil monohydrochloride[no description available]medium20
aminopterin[no description available]medium20dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen
azepexole, dihydrochloride[no description available]medium10
2,5-dimethoxy-4-iodoamphetamine hydrochloride[no description available]medium10
abt 980[no description available]medium20
sk&f 75670[no description available]medium20
esatenolol[no description available]medium10atenololbeta-adrenergic antagonist
nbi 27914[no description available]medium20dialkylarylamine;
tertiary amino compound
sb 216763[no description available]medium20indoles;
maleimides
(R)-atenolol[no description available]medium10atenolol
memantine hydrochloride[no description available]medium20hydrochlorideantidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
pefabloc[no description available]medium10
pongidae[no description available]medium20
succinylproline[no description available]medium10N-acyl-amino acid
sb 205384[no description available]medium20thienopyridine
hydrastine[no description available]medium20isoquinolinesmetabolite
gabaculine hydrochloride[no description available]medium10
etiron monohydrobromide[no description available]medium10
bmy 7378[no description available]medium10
vesamicol[no description available]medium10
cortisone[no description available]medium2011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
vincristine sulfate[no description available]medium20organic sulfate saltantineoplastic agent;
geroprotector
n-methylserotonin oxalate salt[no description available]medium10
nsc 95397[no description available]medium201,4-naphthoquinones
wortmannin[no description available]medium20acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
lithium chloride[no description available]medium10inorganic chloride;
lithium salt		antimanic drug;
geroprotector
canavanine[no description available]medium10amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		phytogenic insecticide;
plant metabolite
5-hydroxytryptophan[no description available]medium105-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
plant metabolite
ouabain[no description available]medium7011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
tosylphenylalanyl chloromethyl ketone[no description available]medium20alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor
monoiodotyrosine[no description available]medium10amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite
nitroarginine[no description available]medium40guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
willardiine[no description available]medium10amino acid zwitterion;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid
cortodoxone[no description available]medium30deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
amiodarone hydrochloride[no description available]medium30aromatic ketone
dicyclomine hydrochloride[no description available]medium30hydrochlorideantispasmodic drug;
muscarinic antagonist
metyrosine[no description available]medium10L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		antihypertensive agent;
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
nortriptyline hydrochloride[no description available]medium30organic tricyclic compoundgeroprotector
paromomycin sulfate[no description available]medium10
Dubinidine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
cyclopamine[no description available]medium10piperidinesglioma-associated oncogene inhibitor
s-(4-azidophenacyl)glutathione[no description available]medium10peptide
hydroxylamine hydrochloride[no description available]medium20organic molecular entity
sb 228357[no description available]medium20indolyl carboxylic acid
3,5-dihydroxyphenylglycine[no description available]medium10amino acid zwitterion;
non-proteinogenic L-alpha-amino acid;
resorcinols
actinonin[no description available]medium20
vinpocetine[no description available]medium30alkaloidgeroprotector
dihydroergocristine monomesylate[no description available]medium30methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent
tretinoin[no description available]medium50retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
resveratrol[no description available]medium30resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
oleic acid[no description available]medium20octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
thapsigargin[no description available]medium40butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
brivudine[no description available]medium10
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol[no description available]medium20carbotetracyclic compound;
polyphenol		estrogen receptor agonist;
estrogen receptor antagonist;
geroprotector;
neuroprotective agent
2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid[no description available]medium10
L-cycloserine[no description available]medium104-amino-1,2-oxazolidin-3-oneanti-HIV agent;
anticonvulsant;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
1,4-dideoxy-1,4-imino-d-arabinitol[no description available]medium10
purvalanol a[no description available]medium10purvalanol
melphalan[no description available]medium20L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
isoliquiritigenin[no description available]medium20chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist
gw9662[no description available]medium20benzamides
calmidazolium[no description available]medium20organic chloride saltapoptosis inducer;
calmodulin antagonist
tropisetron hydrochloride[no description available]medium20
Reactive blue 2[no description available]medium10anthraquinone
5,6-dichloro-1-ethyl-1,3-dihydro-2h-benzimidazol-2-one[no description available]medium10dichlorobenzene
quinidine sulfate[no description available]medium20
ipratropium bromide anhydrous[no description available]medium20
methamilane methiodide[no description available]medium20
pilocarpine nitrate[no description available]medium20
r 59949[no description available]medium20diarylmethane
methylatropine nitrate[no description available]medium20
sb 366791[no description available]medium20
ag-213[no description available]medium20
3,3',4,5'-tetrahydroxystilbene[no description available]medium20catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor
bemesetron[no description available]medium20
(S)-(-)-pindolol[no description available]medium10pindolol
levosulpiride[no description available]medium10sulpirideantidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
caffeic acid[no description available]medium20caffeic acidgeroprotector;
mouse metabolite
4-fluorophenyl-L-alanine[no description available]medium204-fluorophenylalanine;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid
urocanic acid[no description available]medium20urocanic acidhuman metabolite
cotinine[no description available]medium20N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite
sulindac[no description available]medium10monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent
cysteine sulfinic acid[no description available]medium10organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite
d-ap7[no description available]medium10
(1R,2S)-tranylcypromine hydrochloride[no description available]medium20hydrochloride
tacrine hydrochloride[no description available]medium30
4-bromotetramisole, oxalate (1:1), salt(s)-isomer[no description available]medium20
3-hydroxybenzylhydrazine hydrochloride[no description available]medium20
1-(3-chlorophenyl)biguanide hydrochloride[no description available]medium20
4-chlorophenylalanine methyl ester, hydrochloride, (dl)-isomer[no description available]medium10
capsazepine[no description available]medium20benzazepine;
catechols;
monochlorobenzenes;
thioureas		capsaicin receptor antagonist
diphenyleneiodium chloride[no description available]medium20organic chloride saltEC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
G-protein-coupled receptor agonist
azetidine-2,4-dicarboxylic acid, (cis)-isomer[no description available]medium10
tamoxifen citrate[no description available]medium20citrate saltangiogenesis inhibitor;
anticoronaviral agent
pimagedine hydrochloride[no description available]medium10
Betaine Aldehyde Chloride[no description available]medium10quaternary ammonium salt
eskazine[no description available]medium30
monastrol[no description available]medium10enoate ester;
ethyl ester;
phenols;
racemate;
thioureas		antileishmanial agent;
antimitotic;
antineoplastic agent;
EC 3.5.1.5 (urease) inhibitor
u 0126[no description available]medium20aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
4-diphenylacetoxy-n-methylpiperidine methiodide[no description available]medium20iodide salt;
quaternary ammonium salt		cholinergic antagonist;
muscarinic antagonist
1-(4-hydroxybenzyl)imidazole-2-thiol[no description available]medium10
bp 897[no description available]medium20naphthalenecarboxamide
trequinsin hydrochloride[no description available]medium20
neboglamine[no description available]medium10
benzatropine methanesulfonate[no description available]medium20
sb 203186[no description available]medium10indolyl carboxylic acid
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea[no description available]medium201,2-thiazoles;
indoles;
ureas		receptor modulator;
serotonergic antagonist
gw 7647[no description available]medium20aryl sulfide;
monocarboxylic acid;
ureas		PPARalpha agonist
ro 41-0960[no description available]medium20
cgp 13501[no description available]medium10alkylbenzene
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide[no description available]medium20
brl 15572[no description available]medium20monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist
or486[no description available]medium10
fg 9041[no description available]medium20quinoxaline derivative
iik7[no description available]medium10
sb 415286[no description available]medium20C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
dm 235[no description available]medium20
jhw 015[no description available]medium20indolecarboxamide
bw 723c86[no description available]medium20tryptamines
sc 560[no description available]medium20aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug
sc-19220[no description available]medium10aromatic ether
le 300[no description available]medium20indoles
ly 367265[no description available]medium20dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor
diclofenac sodium[no description available]medium20organic sodium salt
cgp 7930[no description available]medium20alkylbenzene
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole[no description available]medium20phenols;
pyrazoles		estrogen receptor agonist
sib 1757[no description available]medium20
sphingosine[no description available]medium10sphing-4-eninehuman metabolite;
mouse metabolite
apigenin[no description available]medium20trihydroxyflavoneantineoplastic agent;
metabolite
luteolin[no description available]medium103'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist
daphnetin[no description available]medium20hydroxycoumarin
genistein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
pulmicort[no description available]medium3011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen
timolol maleate[no description available]medium30maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
brompheniramine maleate[no description available]medium30maleate saltanti-allergic agent
chlorpheniramine maleate[no description available]medium20organic molecular entity
clemastine fumarate[no description available]medium20fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist
methylergonovine maleate[no description available]medium20ergoline alkaloidgeroprotector
astaxanthine[no description available]medium20carotenol;
carotenone		animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite
harman[no description available]medium20harmala alkaloid;
indole alkaloid fundamental parent;
indole alkaloid		anti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite
morin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent
myricetin[no description available]medium207-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite
daidzein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite
caffeic acid phenethyl ester[no description available]medium20alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent
rottlerin[no description available]medium20aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
flupenthixol[no description available]medium10flupenthixoldopaminergic antagonist
n-oleoyldopamine[no description available]medium20catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		TRPV1 agonist
pheniramine maleate[no description available]medium20organic molecular entity
tranilast[no description available]medium30amidobenzoic acid;
cinnamamides;
dimethoxybenzene;
secondary carboxamide		anti-allergic agent;
anti-asthmatic drug;
antineoplastic agent;
aryl hydrocarbon receptor agonist;
calcium channel blocker;
hepatoprotective agent;
nephroprotective agent
trimipramine maleate[no description available]medium20maleate saltantidepressant
isotretinoin[no description available]medium20retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent
xylometazoline hydrochloride[no description available]medium30
flunarizine hydrochloride[no description available]medium20diarylmethane
ketotifen fumarate[no description available]medium30organoammonium saltanti-asthmatic drug;
H1-receptor antagonist
cis-flupenthixol dihydrochloride[no description available]medium20hydrochloridegeroprotector
n-arachidonylglycine[no description available]medium20fatty amide;
N-acylglycine
n-oleoylethanolamine[no description available]medium20endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist
cyclosporine[no description available]medium20homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite
phenoxybenzamine hydrochloride[no description available]medium30organic molecular entity
phenylephrine hydrochloride[no description available]medium20hydrochloride
mepyramine maleate[no description available]medium30
brefeldin a[no description available]medium20macrolide antibioticPenicillium metabolite
fenretinide[no description available]medium20monocarboxylic acid amide;
retinoid		antineoplastic agent;
antioxidant
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid[no description available]medium20benzoic acids;
naphthalenes;
retinoid		antineoplastic agent;
retinoic acid receptor agonist;
teratogenic agent
l-2-(carboxypropyl)glycine[no description available]medium10
4-aminocrotonic acid[no description available]medium10
denopamine[no description available]medium10dimethoxybenzene
l 655,708[no description available]medium20
ro 41-1049[no description available]medium10
sb 200646a[no description available]medium20
seglitide[no description available]medium10
sib 1893[no description available]medium10
su 6656[no description available]medium20
tyrphostin ag 555[no description available]medium30
tyrphostin ag-494[no description available]medium10
tyrphostin b44[no description available]medium20
ag-490[no description available]medium20catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor
ag 112[no description available]medium20
ag 183[no description available]medium20
semaxinib[no description available]medium20olefinic compound;
oxindoles;
pyrroles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist
bay 11-7085[no description available]medium20benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor
molsidomine[no description available]medium20ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent
diamide[no description available]medium101,1'-azobis(N,N-dimethylformamide)
nomifensine maleate[no description available]medium20
nalbuphine hydrochloride[no description available]medium20hydrochloride
isoalloxazine[no description available]medium10benzo[g]pteridine-2,4-dione
vinblastine sulfate[no description available]medium30
n-methylscopolamine bromide[no description available]medium20
dextromethorphan hydrobromide[no description available]medium20hydrate;
hydrobromide
naloxone hydrochloride[no description available]medium10hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
s-trans,trans-farnesylthiosalicylic acid[no description available]medium20sesquiterpenoid
sulindac sulfone[no description available]medium10monocarboxylic acid;
organofluorine compound;
sulfone		apoptosis inducer;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
naltrexone hydrochloride[no description available]medium30hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
guanabenz acetate[no description available]medium30dichlorobenzenegeroprotector
nylidrin hydrochloride[no description available]medium30alkylbenzene
triprolidine hydrochloride anhydrous[no description available]medium30hydrochlorideH1-receptor antagonist
famotidine[no description available]medium101,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
fenoterol[no description available]medium10hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
tiapridex[no description available]medium20benzamides
quipazine maleate[no description available]medium20
n-(2-aminoethyl)-4-chlorobenzamide hydrochloride[no description available]medium10
tulobuterol hydrochloride[no description available]medium20organic molecular entity
hp 029[no description available]medium20
n,n,n-trimethyl-1-(4-stilbenoxy)-2-propylammonium iodide[no description available]medium10
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one[no description available]medium20naphthalenes
nf023[no description available]medium10
nf 449[no description available]medium20
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine[no description available]medium20
gr 46611[no description available]medium10
diacetylmonoxime[no description available]medium10
homatropine hydrobromide, (endo-(+-)-isomer)[no description available]medium20
vancomycin hydrochloride[no description available]medium10
moxisylyte hydrochloride[no description available]medium20monoterpenoid
dizocilpine maleate[no description available]medium30maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
beta-aminopropionitrile fumarate[no description available]medium10
flupirtine[no description available]medium20
zimelidine hydrochloride[no description available]medium20
pregna-4,17-diene-3,16-dione, (17z)-isomer[no description available]medium20
su 4312[no description available]medium20
gw 1929[no description available]medium20benzophenones
protriptyline hydrochloride[no description available]medium30hydrochlorideantidepressant
n(4)-chloroacetylcytosine arabinoside[no description available]medium10
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamide[no description available]medium20
n-(4-amino-2-chlorophenyl)phthalimide[no description available]medium10
cb 34[no description available]medium10
b 43[no description available]medium20aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol[no description available]medium10aporphine alkaloid
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol[no description available]medium10aporphine alkaloid
3-(6-chloro-3-pyridazinyl)-3,8-diazabicyclo(3.2.1)octane[no description available]medium10
2-(3,3-diphenylpropylamino)acetamide[no description available]medium20diarylmethane
4-(2-(phenylsulfonylamino)ethylthio)-2,6-difluorophenoxyacetamide[no description available]medium10
gw2974[no description available]medium10pyridopyrimidine
l 162313[no description available]medium20
l-165041[no description available]medium10aromatic ketone
mrs 1754[no description available]medium20oxopurine
s-nitroso-n-acetylpenicillamine[no description available]medium10nitroso compound;
nitrosothio compound		nitric oxide donor;
vasodilator agent
pd 404182[no description available]medium10
sb 222200[no description available]medium20quinolines
dantrolene sodium[no description available]medium20
cr 2945[no description available]medium20
sb 218795[no description available]medium20quinolines
dihydroceramide[no description available]medium10N-acylsphinganine
epinephrine bitartrate[no description available]medium30
bicuculline methobromide[no description available]medium30
butylscopolammonium bromide[no description available]medium20
butaclamol hydrochloride[no description available]medium30
a 38503[no description available]medium20
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide[no description available]medium10
sk&f 89976-a[no description available]medium10
fluvoxamine maleate[no description available]medium20(trifluoromethyl)benzenes
naloxone benzoylhydrazone[no description available]medium20
2-methyl-6-(phenylethynyl)pyridine hydrochloride[no description available]medium20hydrochlorideanxiolytic drug;
metabotropic glutamate receptor antagonist
amiprilose[no description available]medium10
(R)-fluoxetine hydrochloride[no description available]medium20hydrochlorideantidepressant;
serotonin uptake inhibitor
desmethylselegiline hydrochloride[no description available]medium10
3-morpholino-sydnonimine monohydrochloride[no description available]medium30
t 1032[no description available]medium20
qx-314 bromide[no description available]medium10
(S)-fluoxetine hydrochloride[no description available]medium20hydrochlorideantidepressant;
serotonin uptake inhibitor
sr 59230a[no description available]medium20
u 74389g[no description available]medium20
1-(2-methoxyphenyl)piperazine hydrochloride[no description available]medium20
y 27632, dihydrochloride, (4(r)-trans)-isomer[no description available]medium10
noscapine hydrochloride[no description available]medium20
a 77636[no description available]medium20hydrochlorideantiparkinson drug;
dopamine agonist
cgp 20712a[no description available]medium20
levodopa methyl ester hydrochloride[no description available]medium20
benalfocin hydrochloride[no description available]medium10
lu 19005[no description available]medium20
benoxathian hydrochloride[no description available]medium20
((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1h-inden-5-yl)oxy)acetic acid, (+)-isomer[no description available]medium20
cefotaxime sodium[no description available]medium20organic sodium salt
calpain inhibitor iii[no description available]medium20
GR 127935 hydrochloride[no description available]medium20hydrochlorideserotonergic antagonist
mrs 1845[no description available]medium20
1-aminocyclopropane-1-carboxylic acid hydrochloride[no description available]medium20
alaproclate hydrochloride[no description available]medium20
ubenimex[no description available]medium20peptide
3-chloroalanine hydrochloride, (l-ala)-isomer[no description available]medium10
dsp 4 hydrochloride[no description available]medium20
calcimycin[no description available]medium130benzoxazole
(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride[no description available]medium20hydrochloridealpha-adrenergic antagonist
2-cyclooctyl-2-hydroxyethylamine hydrochloride[no description available]medium20
cirazoline monohydrochloride[no description available]medium20
adtn[no description available]medium20
apocodeine hydrochloride, (r)-isomer[no description available]medium20
Dihydro-beta-erythroidine hydrobromide[no description available]medium10indoles
lilly 78335[no description available]medium20
efaroxan hydrochloride[no description available]medium20
fenoldopam hydrobromide[no description available]medium20
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride[no description available]medium20hydrochloridedopamine uptake inhibitor
guvacine hydrochloride[no description available]medium10
7-hydroxy-2-n,n-dipropylaminotetralin hydrobromide[no description available]medium20
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (r)-isomer,[no description available]medium20organic molecular entity
1-(2-(4-(4-fluoro-benzoyl)-piperidin-1-yl)-ethyl)-3,3-dimethyl-1,2-dihydro-indol-2-one[no description available]medium20hydrochloridereceptor modulator;
serotonergic antagonist
4-iodoclonidine[no description available]medium20
4-methylpyrazole monohydrochloride[no description available]medium10
tele-methylhistamine[no description available]medium10
alpha-methyltyrosine methyl ester, monohydrochloride[no description available]medium20
octoclothepine maleate[no description available]medium20
2-(n-phenethyl-n-propyl)amino-5-hydroxytetralin hydrochloride[no description available]medium20
du 24565[no description available]medium20
2-methoxyidazoxan hydrochloride[no description available]medium20
ro 25-6981[no description available]medium20
sk&f 77434[no description available]medium20hydrobromidedopamine agonist;
prodrug
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea[no description available]medium20organic heterotetracyclic compound;
organonitrogen heterocyclic compound
demethylcantharidin[no description available]medium20
atropine sulfate[no description available]medium20
1-deoxynojirimycin hydrochloride[no description available]medium10
win 62577[no description available]medium20
quinine sulfate[no description available]medium20hydrate
quercetin[no description available]medium20
rv 538, (r-(r*,r*))-isomer[no description available]medium20
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (1s-cis)-isomer[no description available]medium20
valproate sodium[no description available]medium10organic sodium saltgeroprotector
u 63557a[no description available]medium10
taurocholic acid, monosodium salt[no description available]medium20bile salt
cefmetazole sodium[no description available]medium10organic sodium saltantimicrobial agent
fusidate sodium[no description available]medium20
cephapirin sodium[no description available]medium10cephalosporin;
organic sodium salt		antibacterial drug
sodium cephalothin[no description available]medium10organic sodium salt
cefazolin sodium[no description available]medium30organic sodium salt
5-hydroxydecanoic acid, monosodium salt[no description available]medium10
ro13-9904[no description available]medium10
phenytoin sodium[no description available]medium10
cr 1409[no description available]medium10
cortisol succinate, sodium salt[no description available]medium20organic molecular entity
piroxicam[no description available]medium40benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
lfm a13[no description available]medium10aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor
l 701324[no description available]medium10quinolines
hispidin[no description available]medium202-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite
minocycline hydrochloride[no description available]medium20
demeclocycline hydrochloride[no description available]medium30
acyclovir[no description available]medium202-aminopurines;
oxopurine		antimetabolite;
antiviral drug
sepiapterin[no description available]medium10sepiapterin
isoxanthopterin[no description available]medium10dihydroxypteridine
clozapine[no description available]medium30benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
ganciclovir[no description available]medium202-aminopurines;
oxopurine		antiinfective agent;
antiviral drug
zaprinast[no description available]medium20triazolopyrimidines
allopurinol[no description available]medium30nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
thiolactomycin[no description available]medium10
2,4-diaminohypoxanthine[no description available]medium10hydroxypyrimidine
quazinone[no description available]medium10
8-bromocyclic gmp, sodium salt[no description available]medium20organic sodium saltmuscle relaxant;
protein kinase G agonist
ag-879[no description available]medium20
osip 339391[no description available]medium10
cvt-6883[no description available]medium10
psb603[no description available]medium10
n-benzo(1,3)dioxol-5-yl-2-(5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1h-purin-8-yl)-1-methyl-1h-pyrazol-3-yloxy)-acetamide[no description available]medium10
adenine[no description available]medium2406-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
9-benzyladenine[no description available]medium20
6-n-hydroxylaminopurine[no description available]medium106-aminopurines;
hydroxylamines;
nucleobase analogue		mutagen;
teratogenic agent
3-deazaadenine[no description available]medium10
8-hydroxyadenine[no description available]medium106-aminopurines;
heteroaryl hydroxy compound;
nucleobase analogue;
oxopurine		bacterial metabolite;
human metabolite
7-deazaadenine[no description available]medium10
9-deazahypoxanthine[no description available]medium10
cgp 52411[no description available]medium10phthalimidesgeroprotector;
tyrosine kinase inhibitor
aa 861[no description available]medium301,4-benzoquinones;
acetylenic compound;
primary alcohol		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor
bu 224[no description available]medium10quinolines
chloroquine[no description available]medium10aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
ml 9[no description available]medium10naphthalenes;
sulfonic acid derivative
pd 169316[no description available]medium10imidazoles
2-bromoergocryptine mesylate[no description available]medium10methanesulfonate saltantiparkinson drug
salmeterol xinafoate[no description available]medium10naphthoic acid
finasteride[no description available]medium103-oxo steroid;
aza-steroid;
delta-lactam		androgen antagonist;
antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
eliprodil[no description available]medium10monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary alcohol;
tertiary amino compound
sertraline hydrochloride[no description available]medium10hydrochlorideantidepressant;
serotonin uptake inhibitor
opipramol hydrochloride[no description available]medium10
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole[no description available]medium10ether;
imidazoles;
monomethoxybenzene		TRP channel blocker
u 78517f[no description available]medium10
mk 912[no description available]medium10
sk&f 86466[no description available]medium10benzazepine
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine[no description available]medium10
dizocilpine[no description available]medium10secondary amino compound;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
6-bromoindirubin-3'-oxime[no description available]medium10
h 89[no description available]medium10N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
phenylthiazolylthiourea[no description available]medium10
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)[no description available]medium10benzimidazoles
tg 003[no description available]medium10
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene[no description available]medium10C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector
l 663536[no description available]medium10aryl sulfide;
indoles;
monocarboxylic acid;
monochlorobenzenes		antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
leukotriene antagonist
su 9516[no description available]medium10
ml 10302[no description available]medium10
ag 538[no description available]medium10
bw b70c[no description available]medium10aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
mg 624[no description available]medium10
5-(4-phenylbutoxy)psoralen[no description available]medium10aromatic ether;
benzenes;
psoralens		geroprotector;
immunosuppressive agent;
potassium channel blocker
bisoprolol, fumarate (1:1) salt[no description available]medium10
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride[no description available]medium10
ro 8-4304[no description available]medium10
sb 203186[no description available]medium10
2-hydroxyapomorphine, (r)-isomer[no description available]medium10
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide[no description available]medium10hydrobromidedopamine agonist;
prodrug
nebularine[no description available]medium30purine ribonucleoside;
purines D-ribonucleoside		fungal metabolite
8-azanebularine[no description available]medium10
regadenoson[no description available]medium10purine nucleoside
wr-142,490[no description available]medium10[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanolantimalarial
istradefylline[no description available]medium10oxopurine
binodenoson[no description available]medium10
atl 146e[no description available]medium10
st 1535[no description available]medium10
2-(2-furanyl)-7-(2-(4-(4-(2-methoxyethoxy)phenyl)-1-piperazinyl)ethyl)-7h-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidine-5-amine[no description available]medium10
tozadenant[no description available]medium10benzothiazoles
v 2006[no description available]medium10
cordycepin[no description available]medium203'-deoxyribonucleoside;
adenosines		antimetabolite;
nucleoside antibiotic
2-fluoroadenine[no description available]medium20organofluorine compound;
purines		antineoplastic agent
adenosine 2',3'-ribo-epoxide[no description available]medium10
2-chloroadenine[no description available]medium20
2-chloro-3'-deoxyadenosine[no description available]medium470
2-chloro-3'-deoxyadenosine[no description available]medium475
coumarin[no description available]medium10coumarinsfluorescent dye;
human metabolite;
plant metabolite
salicylic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
malic acid[no description available]medium102-hydroxydicarboxylic acid;
C4-dicarboxylic acid		food acidity regulator;
fundamental metabolite
histamine[no description available]medium200aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
naringenin[no description available]medium104'-hydroxyflavanones;
trihydroxyflavanone
niacinamide[no description available]medium20pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
niacin[no description available]medium10pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
pyrazinoic acid[no description available]medium10pyrazinecarboxylic acidantitubercular agent;
drug metabolite
1,10-phenanthroline[no description available]medium10phenanthrolineEC 2.7.1.1 (hexokinase) inhibitor;
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
ro 5-4864[no description available]medium40
5,8,11,14-eicosatetraynoic acid[no description available]medium30long-chain fatty acid
etofylline[no description available]medium10oxopurine
acetarsol[no description available]medium10acetamides;
anilide
astemizole[no description available]medium10benzimidazoles;
piperidines		anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist
bendroflumethiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benzbromarone[no description available]medium101-benzofurans;
aromatic ketone		uricosuric drug
benzothiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
bay h 4502[no description available]medium10biphenyls;
imidazoles
bisacodyl[no description available]medium10diarylmethane
bufexamac[no description available]medium10aromatic ether;
hydroxamic acid		antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
chlorthalidone[no description available]medium10isoindoles;
monochlorobenzenes;
sulfonamide
4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide[no description available]medium10sulfonamide
dapsone[no description available]medium10substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
deferiprone[no description available]medium104-pyridonesiron chelator;
protective agent
dichlorophen[no description available]medium10bridged diphenyl fungicide;
diarylmethane
diflunisal[no description available]medium10monohydroxybenzoic acid;
organofluorine compound		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
dipropizine[no description available]medium10piperazines
dyphylline[no description available]medium10oxopurine;
propane-1,2-diols		bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
muscle relaxant;
vasodilator agent
epirizole[no description available]medium10aromatic ether
ethacrynic acid[no description available]medium10aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
myambutol[no description available]medium10amino alcohol
ethoxzolamide[no description available]medium10aromatic ether;
benzothiazoles;
sulfonamide		antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
4-biphenylylacetic acid[no description available]medium10biphenyls;
monocarboxylic acid		non-steroidal anti-inflammatory drug
fenbufen[no description available]medium104-oxo monocarboxylic acid;
biphenyls		non-steroidal anti-inflammatory drug
flucytosine[no description available]medium10aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
flumequine[no description available]medium103-oxo monocarboxylic acid;
organofluorine compound;
pyridoquinoline;
quinolone antibiotic
flurbiprofen[no description available]medium10fluorobiphenyl;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
gemfibrozil[no description available]medium10aromatic etherantilipemic drug
fluorometholone[no description available]medium10
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium40isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
harmaline[no description available]medium10harmala alkaloidoneirogen
hexachlorophene[no description available]medium10bridged diphenyl fungicide;
polyphenol;
trichlorobenzene		acaricide;
antibacterial agent;
antifungal agrochemical;
antiseptic drug
hexamethylene bisacetamide[no description available]medium10acetamides
hycanthone[no description available]medium10thioxanthenesmutagen;
schistosomicide drug
hydroflumethiazide[no description available]medium10benzothiadiazine;
thiazide		antihypertensive agent;
diuretic
amrinone[no description available]medium10bipyridinesEC 3.1.4.* (phosphoric diester hydrolase) inhibitor
indapamide[no description available]medium10indoles;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic
indoprofen[no description available]medium10gamma-lactam;
isoindoles;
monocarboxylic acid		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
ipriflavone[no description available]medium10aromatic ether;
isoflavones		bone density conservation agent
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
itraconazole[no description available]medium10piperazines
khellin[no description available]medium10furanochromone;
organic heterotricyclic compound;
oxacycle		anti-asthmatic agent;
bronchodilator agent;
cardiovascular drug;
vasodilator agent
ly 171883[no description available]medium10acetophenones;
aromatic ether;
phenols;
tetrazoles		anti-asthmatic drug;
leukotriene antagonist
edaravone[no description available]medium10pyrazoloneantioxidant;
radical scavenger
mefenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
vitamin k 3[no description available]medium101,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
methazolamide[no description available]medium10sulfonamide;
thiadiazoles
methocarbamol[no description available]medium10aromatic ether;
carbamate ester;
secondary alcohol
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
moclobemide[no description available]medium10benzamides;
monochlorobenzenes;
morpholines		antidepressant;
environmental contaminant;
xenobiotic
acecainide[no description available]medium10acetamides;
benzamides		anti-arrhythmia drug
nabumetone[no description available]medium10methoxynaphthalene;
methyl ketone		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
nalidixic acid[no description available]medium101,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
nevirapine[no description available]medium10cyclopropanes;
dipyridodiazepine		antiviral drug;
HIV-1 reverse transcriptase inhibitor
norfloxacin[no description available]medium20fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug;
DNA synthesis inhibitor;
environmental contaminant;
xenobiotic
cm 7116[no description available]medium10benzodiazepine
omeprazole[no description available]medium10aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
aminosalicylic acid[no description available]medium10aminobenzoic acid;
phenols		antitubercular agent
phenindione[no description available]medium10aromatic ketone;
beta-diketone		anticoagulant
phenolphthalein[no description available]medium10phenols
4-phenylbutyric acid[no description available]medium10monocarboxylic acidantineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor;
prodrug
pipemidic acid[no description available]medium10amino acid;
monocarboxylic acid;
N-arylpiperazine;
pyridopyrimidine;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor
probenecid[no description available]medium10benzoic acids;
sulfonamide		uricosuric drug
probucol[no description available]medium10dithioketal;
polyphenol		anti-inflammatory drug;
anticholesteremic drug;
antilipemic drug;
antioxidant;
cardiovascular drug
prochlorperazine[no description available]medium10N-alkylpiperazine;
N-methylpiperazine;
organochlorine compound;
phenothiazines		alpha-adrenergic antagonist;
antiemetic;
cholinergic antagonist;
dopamine receptor D2 antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic
proxyphylline[no description available]medium10oxopurine
pyrimethamine[no description available]medium10aminopyrimidine;
monochlorobenzenes		antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
ronidazole[no description available]medium10C-nitro compound;
carbamate ester;
imidazoles		antiparasitic agent;
antiprotozoal drug
salicylamide[no description available]medium10phenols;
salicylamides		antirheumatic drug;
non-narcotic analgesic
aldactazide[no description available]medium10steroid lactone
streptonigrin[no description available]medium10pyridines;
quinolone		antimicrobial agent;
antineoplastic agent
sulfabenzamide[no description available]medium10benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug
sulfacetamide[no description available]medium10N-sulfonylcarboxamide;
substituted aniline		antibacterial drug;
antiinfective agent;
antimicrobial agent;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfadimethoxine[no description available]medium10aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamerazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen
sulfamethazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic
sulfamethizole[no description available]medium10sulfonamide antibiotic;
sulfonamide;
thiadiazoles		antiinfective agent;
antimicrobial agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfamethoxazole[no description available]medium10isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
sulfamethoxypyridazine[no description available]medium10pyridazines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
tegafur[no description available]medium10organohalogen compound;
pyrimidines
terazosin[no description available]medium20furans;
piperazines;
primary amino compound;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
antineoplastic agent
thiabendazole[no description available]medium101,3-thiazoles;
benzimidazole fungicide;
benzimidazoles		antifungal agrochemical;
antinematodal drug
tinidazole[no description available]medium10imidazolesantiamoebic agent;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug
tolnaftate[no description available]medium10monothiocarbamic esterantifungal drug
trapidil[no description available]medium10triazolopyrimidines
trichlormethiazide[no description available]medium10benzothiadiazine;
sulfonamide antibiotic		antihypertensive agent;
diuretic
tyramine[no description available]medium10monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
vesamicol[no description available]medium10piperidines
xylazine[no description available]medium201,3-thiazine;
methylbenzene;
secondary amino compound		alpha-adrenergic agonist;
analgesic;
emetic;
muscle relaxant;
sedative
zopiclone[no description available]medium10monochloropyridine;
pyrrolopyrazine		central nervous system depressant;
sedative
hydrocortisone acetate[no description available]medium10cortisol ester;
tertiary alpha-hydroxy ketone
oxyphenonium bromide[no description available]medium10
floxuridine[no description available]medium30nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
neostigmine methylsulfate[no description available]medium10arylammonium sulfate saltEC 3.1.1.8 (cholinesterase) inhibitor
prednisolone acetate[no description available]medium10corticosteroid hormone
trichlorfon[no description available]medium10organic phosphonate;
organochlorine compound;
phosphonic ester		agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
azauridine[no description available]medium20N-glycosyl-1,2,4-triazineantimetabolite;
antineoplastic agent;
drug metabolite
desoxycorticosterone acetate[no description available]medium10corticosteroid hormone
benzyltrimethylammonium chloride[no description available]medium10
ethinyl estradiol[no description available]medium1017-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
uridine[no description available]medium40uridinesdrug metabolite;
fundamental metabolite;
human metabolite
tolazoline hydrochloride[no description available]medium10benzenes
acetylcholine chloride[no description available]medium10quaternary ammonium salt
desoxycorticosterone[no description available]medium1020-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
fluocinolone acetonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
organic heteropentacyclic compound;
primary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
norethynodrel[no description available]medium10oxo steroid
ampicillin[no description available]medium10beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
trifluridine[no description available]medium10nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
EC 2.1.1.45 (thymidylate synthase) inhibitor
4-hydroxypropiophenone[no description available]medium10acetophenones
medroxyprogesterone acetate[no description available]medium1020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester		adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive
isopropamide iodide[no description available]medium10diarylmethane
mestranol[no description available]medium1017beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound		prodrug;
xenoestrogen
triamcinolone acetonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
dehydrocholic acid[no description available]medium1012-oxo steroid;
3-oxo-5beta-steroid;
7-oxo steroid;
oxo-5beta-cholanic acid		gastrointestinal drug
methylprednisolone[no description available]medium206-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic
9,10-phenanthrenequinone[no description available]medium10phenanthrenes
phenothiazine[no description available]medium10phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger
mecoprop[no description available]medium10aromatic ether;
monocarboxylic acid;
monochlorobenzenes
2-methyl-4-chlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
monochlorobenzenes		environmental contaminant;
phenoxy herbicide;
synthetic auxin
arsanilic acid[no description available]medium10organoarsonic acid
3-aminobenzoic acid[no description available]medium10aminobenzoic acid
thiodipropionic acid[no description available]medium10dicarboxylic acid
maltol[no description available]medium104-pyranonesmetabolite
cinchophen[no description available]medium10quinolines
phenazopyridine hydrochloride[no description available]medium10hydrochloridecarcinogenic agent;
local anaesthetic;
non-narcotic analgesic
protocatechualdehyde[no description available]medium10dihydroxybenzaldehyde
20-alpha-dihydroprogesterone[no description available]medium1020-hydroxypregn-4-en-3-onehuman metabolite;
mouse metabolite
quinestrol[no description available]medium1017-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
tripelennamine hydrochloride[no description available]medium10
chlormadinone acetate[no description available]medium10corticosteroid hormone
fluocinonide[no description available]medium10organic molecular entity
fluorometholone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
xanthinol niacinate[no description available]medium10
glycyrrhetinic acid[no description available]medium10cyclic terpene ketone;
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		immunomodulator;
plant metabolite
medroxyprogesterone[no description available]medium1017alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
tertiary alpha-hydroxy ketone		contraceptive drug;
progestin;
synthetic oral contraceptive
1,2-naphthoquinone[no description available]medium101,2-naphthoquinonesaryl hydrocarbon receptor agonist;
carcinogenic agent
4,4'-bipyridyl[no description available]medium10bipyridine
monoacetyldapsone[no description available]medium10acetamides;
anilide;
secondary carboxamide;
sulfone
chlorotrianisene[no description available]medium10chloroalkeneantineoplastic agent;
estrogen receptor modulator;
xenoestrogen
aminacrine[no description available]medium10
isoxsuprine hydrochloride[no description available]medium10alkylbenzene
megestrol acetate[no description available]medium1020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
steroid ester		antineoplastic agent;
appetite enhancer;
contraceptive drug;
progestin;
synthetic oral contraceptive
2-hydroxyacetanilide[no description available]medium10acetamides;
phenols		anti-inflammatory agent;
antineoplastic agent;
antirheumatic drug;
apoptosis inducer;
platelet aggregation inhibitor;
xenobiotic metabolite
clopamide[no description available]medium10sulfonamide
phosmet[no description available]medium10organic thiophosphate;
organothiophosphate insecticide;
phthalimides		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
levonorgestrel[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound		contraceptive drug;
female contraceptive drug;
progestin;
synthetic oral contraceptive
malononitrile dimer[no description available]medium10
diphenyl disulfide[no description available]medium10benzenes
estradiol valerate[no description available]medium10steroid ester
tetramethylpyrazine[no description available]medium10alkaloid;
pyrazines		antineoplastic agent;
apoptosis inhibitor;
bacterial metabolite;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
2,2'-dipyridylamine[no description available]medium10
pregnenolone carbonitrile[no description available]medium10aliphatic nitrile
flurandrenolone[no description available]medium1021-hydroxy steroid
diethylcarbamazine citrate[no description available]medium10piperazinecarboxamide
guaiacoxyacetic acid[no description available]medium10
methylene diphosphonate[no description available]medium101,1-bis(phosphonic acid)bone density conservation agent;
chelator
amiloride hydrochloride, anhydrous[no description available]medium10hydrochloridediuretic;
sodium channel blocker
flumethasone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
azaribine[no description available]medium10acetate ester;
N-glycosyl-1,2,4-triazine		antipsoriatic;
prodrug
hydrocortisone hemisuccinate[no description available]medium10dicarboxylic acid monoester;
hemisuccinate;
tertiary alpha-hydroxy ketone
mebeverine hydrochloride[no description available]medium10
stavudine[no description available]medium10dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
clidinium bromide[no description available]medium10
diloxanide furoate[no description available]medium10carboxylic ester;
furans;
organochlorine compound;
tertiary carboxamide		antiamoebic agent;
prodrug
nitroxoline[no description available]medium10C-nitro compound;
monohydroxyquinoline		antifungal agent;
antiinfective agent;
antimicrobial agent;
renal agent
alverine citrate[no description available]medium10citrate salt;
organoammonium salt		antispasmodic drug;
cholinergic antagonist
cyclogyl[no description available]medium10
6-nitroindazole[no description available]medium10
hydrocortisone-17-butyrate[no description available]medium10butyrate ester;
cortisol ester;
primary alpha-hydroxy ketone		dermatologic drug;
drug allergen
pentamethylmelamine[no description available]medium10
eedq[no description available]medium10
ornidazole[no description available]medium10C-nitro compound;
imidazoles;
organochlorine compound;
secondary alcohol		antiamoebic agent;
antibacterial drug;
antiinfective agent;
antiprotozoal drug;
antitrichomonal drug;
epitope
tetridamin[no description available]medium10
capobenic acid[no description available]medium10benzamides
thymolphthalein[no description available]medium10terpene lactone
clobetasol propionate[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid		anti-inflammatory drug
frentizole[no description available]medium10
eterobarb[no description available]medium10barbiturates
oxcarbazepine[no description available]medium10cyclic ketone;
dibenzoazepine		anticonvulsant;
drug allergen
moricizine hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug
proroxan hydrochloride[no description available]medium10
etomidate[no description available]medium10imidazoles
bezafibrate[no description available]medium10aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
sq-11725[no description available]medium10
picobenzide[no description available]medium10
triadimenol[no description available]medium10aromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite
cerm-1978[no description available]medium10hydrochloride
dazoxiben hydrochloride[no description available]medium10
lovastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
tobramycin sulfate[no description available]medium10
benzylaminopurine[no description available]medium106-aminopurinescytokinin;
plant metabolite
norharman[no description available]medium10beta-carbolines;
mancude organic heterotricyclic parent		fungal metabolite;
marine metabolite
ticlopidine hydrochloride[no description available]medium10hydrochloride
sulconazole, mononitrate, (+-)-isomer[no description available]medium10conazole antifungal drug;
imidazole antifungal drug;
organic nitrate salt
acetylcholine bromide[no description available]medium10bromide salt;
quaternary ammonium salt
aloxistatin[no description available]medium10epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide		anticoronaviral agent;
cathepsin B inhibitor
tryptamide[no description available]medium10
oxyphencyclimine hydrochloride[no description available]medium10pyrimidines
diphenylpyraline hydrochloride[no description available]medium10hydrochloridecholinergic antagonist;
H1-receptor antagonist
mepivacaine hydrochloride[no description available]medium10hydrochloride;
piperidinecarboxamide		local anaesthetic
diphenidol hydrochloride[no description available]medium10diarylmethane
edoxudin[no description available]medium10pyrimidine 2'-deoxyribonucleoside
6-ketoestradiol[no description available]medium10
17 beta-estradiol hemisuccinate[no description available]medium10
amizyl[no description available]medium10
salicylhydroxamic acid[no description available]medium10hydroxamic acid;
phenols		antibacterial drug;
EC 1.11.2.2 (myeloperoxidase) inhibitor;
EC 3.5.1.5 (urease) inhibitor;
trypanocidal drug
1,7-phenanthroline[no description available]medium10phenanthroline
3-fluoro-4-hydroxyphenylacetic acid[no description available]medium10
dyclonine hydrochloride[no description available]medium10hydrochloridetopical anaesthetic
miconazole nitrate[no description available]medium10
econazole nitrate[no description available]medium10
2,4-dimethoxybenzaldehyde[no description available]medium10
enrofloxacin[no description available]medium20cyclopropanes;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		antibacterial agent;
antimicrobial agent;
antineoplastic agent
clobetasone butyrate[no description available]medium10organic molecular entity
diflorasone diacetate[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
fluorinated steroid;
glucocorticoid		anti-inflammatory drug;
antipruritic drug
hydroxyzine dihydrochloride[no description available]medium10
betamipron[no description available]medium10organonitrogen compound;
organooxygen compound
secnidazole[no description available]medium10C-nitro compound;
imidazoles;
secondary alcohol		epitope
ergocornine[no description available]medium10ergot alkaloid
pramoxine hydrochloride[no description available]medium10aromatic ether
butyrylcholine chloride[no description available]medium10
1-benzylimidazole[no description available]medium10
chloropyramine hydrochloride[no description available]medium10
6-aminoindazole[no description available]medium10indazoles
5-aminoindazole[no description available]medium10
2-methylhippuric acid[no description available]medium10N-acylglycinemetabolite
meclizine hydrochloride[no description available]medium10
11-hydroxyprogesterone, (11alpha)-isomer[no description available]medium1011alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid
malic acid, (r)-isomer[no description available]medium10malic acid
21-deoxycortisol[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy-C21-steroid;
deoxycortisol;
tertiary alpha-hydroxy ketone		human blood serum metabolite;
mouse metabolite
estrone 3-methyl ether[no description available]medium10
e-250[no description available]medium10
rac-glycerol 1-monodecanoate[no description available]medium10rac-1-monoacylglycerol
nipecotic acid amide[no description available]medium10piperidinecarboxamide
levcromakalim[no description available]medium101-benzopyran
tachistin[no description available]medium10
cortisol octanoate[no description available]medium10corticosteroid hormone
armepavine[no description available]medium10
bicuculline methiodide[no description available]medium20
beta-carboline-3-carboxylic acid ethyl ester[no description available]medium10beta-carbolines
tryptoline[no description available]medium10beta-carbolines
gamma-fagarine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
Zearalanone[no description available]medium10macrolide;
resorcinols
butethamate citrate[no description available]medium10
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol[no description available]medium10piperidines
1,3-dimethylbenzimidazoline-2-thione[no description available]medium10
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine[no description available]medium10leucine derivative
desloratadine[no description available]medium10benzocycloheptapyridineanti-allergic agent;
cholinergic antagonist;
drug metabolite;
H1-receptor antagonist
dichloro-1,2-diaminocyclohexane platinum complex[no description available]medium10
1,4-di(2'-thienyl)-1,4-butadione[no description available]medium10
methyl 5-aminolevulinate hydrochloride[no description available]medium10hydrochlorideantineoplastic agent;
dermatologic drug;
photosensitizing agent;
prodrug
antazoline phosphate[no description available]medium10
pridinol mesylate[no description available]medium10
17 alpha-hydroxyprogesterone caproate[no description available]medium10corticosteroid hormone
5-fluorotryptamine monohydrochloride[no description available]medium10
piribedil mesylate[no description available]medium10
serc[no description available]medium10
procyclidine hydrochloride[no description available]medium10hydrochloride
(7R)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one[no description available]medium10macrolide
equilin[no description available]medium1017-oxo steroid;
3-hydroxy steroid
adrenosterone[no description available]medium1011-oxo steroid;
17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
human urinary metabolite;
marine metabolite
gossypol acetic acid[no description available]medium10
epinastine[no description available]medium10corticosteroid hormone
benzatropine methanesulfonate[no description available]medium10
4',6-dihydroxy-5,7-dimethoxyflavone[no description available]medium10dihydroxyflavone;
dimethoxyflavone
2-hydroxyestradiol[no description available]medium1017beta-hydroxy steroid;
2-hydroxy steroid		carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug
medrysone[no description available]medium10corticosteroid hormone
artisone acetate[no description available]medium10corticosteroid hormone
chondocurine (1beta)-(+-)-isomer[no description available]medium10aromatic ether
4-methoxyxanthone[no description available]medium10
2-methyl-N-[4-(propan-2-ylamino)phenyl]-2-propenamide[no description available]medium10amine
mandelic acid, (s)-isomer[no description available]medium10(2S)-2-hydroxy monocarboxylic acid;
mandelic acid
acebutolol hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympathomimetic agent
difluprednate[no description available]medium10butyrate ester;
corticosteroid hormone
dironyl[no description available]medium10organic molecular entity
amcinonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
corticosteroid;
fluorinated steroid;
spiroketal		anti-inflammatory drug
flumethasone pivalate[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
pivalate ester;
tertiary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
histidyl-proline diketopiperazine[no description available]medium10dipeptide;
homodetic cyclic peptide;
imidazoles;
pyrrolopyrazine		anti-inflammatory agent;
dopamine uptake inhibitor;
human blood serum metabolite
afimoxifene[no description available]medium10phenols;
tertiary amino compound		antineoplastic agent;
estrogen receptor antagonist;
metabolite
ketoconazole[no description available]medium10cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
aphidicolin[no description available]medium20tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite
azaserine[no description available]medium10carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
maltitol[no description available]medium10alpha-D-glucoside;
glycosyl alditol		laxative;
metabolite;
sweetening agent
chalcone[no description available]medium10chalconeEC 3.2.1.1 (alpha-amylase) inhibitor
thermospine[no description available]medium10
dibenzylidene acetone[no description available]medium10
4-methoxy-1,3-dimethyl-6-thiophen-2-yl-8-cyclohepta[c]furanone[no description available]medium10cycloheptafuran
5-[(5-methoxycarbonyl-2-methyl-3-furanyl)methoxy]-2-methyl-3-benzofurancarboxylic acid 2-methoxyethyl ester[no description available]medium102-methoxyethyl ester;
benzofurans
5,6,7-trimethoxy-1-methyl-2-indolecarboxylic acid[no description available]medium10indolyl carboxylic acid
haplamine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
octotropine methylbromide[no description available]medium10
diethylstilbestrol dipropionate[no description available]medium10
(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol[no description available]medium10alkylbenzene
glycerylphosphorylcholine[no description available]medium10phosphocholines;
sn-glycerol 3-phosphates		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neuroprotective agent;
parasympatholytic;
Saccharomyces cerevisiae metabolite
n-methylscopolamine nitrate[no description available]medium10
propylthiouracil[no description available]medium10pyrimidinethioneantidote to paracetamol poisoning;
antimetabolite;
antioxidant;
antithyroid drug;
carcinogenic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
hormone antagonist
nsc 4347[no description available]medium10
4-methoxy-N1,N3-bis(3-pyridinyl)benzene-1,3-dicarboxamide[no description available]medium10benzamides
physostigmine salicylate[no description available]medium10azaheterocycle salicylate salt;
salicylates
1-[1-oxo-2-[(4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl)oxy]ethyl]-4-piperidinecarboxylic acid[no description available]medium10coumarins
prothionamide[no description available]medium10pyridines
2-(2,3,4-trimethoxyphenyl)-2,3-dihydro-1,3-benzoxazin-4-one[no description available]medium10benzoxazine
dienestrol[no description available]medium10
methylthiouracil[no description available]medium10pyrimidone
4-methoxy-N-(3-pyridinylmethyl)benzamide[no description available]medium10benzamides
5-methyl-4-[(2-oxo-1-benzopyran-7-yl)oxymethyl]-2-furancarboxylic acid methyl ester[no description available]medium10coumarins
2-(1,3-dioxo-2-isoindolyl)-N-(3-nitrophenyl)acetamide[no description available]medium10phthalimides
2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone[no description available]medium10stilbenoid
3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole[no description available]medium10oxadiazole;
ring assembly
3-(3,5-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl)propanoic acid[no description available]medium10psoralens
1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione[no description available]medium10pyrimidotriazine
curcumin[no description available]medium10aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
9-hydroxy-4-[1-oxo-2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-[1]benzopyrano[3,4-b]pyridin-5-one[no description available]medium10pyridochromene
5-bromo-3-pyridinecarboxylic acid [3-(3-methylphenoxy)-4-oxo-1-benzopyran-7-yl] ester[no description available]medium10chromones
5-methyl-4-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxymethyl]-2-furancarboxylic acid[no description available]medium10coumarins
4-methyl-3-(phenylmethyl)-7-[(3,4,5-trimethoxyphenyl)methoxy]-1-benzopyran-2-one[no description available]medium10coumarins
[2-(4-methoxyphenyl)-6-methyl-4-quinolinyl]-(4-morpholinyl)methanone[no description available]medium10quinolines
5-(3,3-dimethyl-2-oxobutoxy)-3,4,7-trimethyl-1-benzopyran-2-one[no description available]medium10coumarins
N-[4-(4-morpholinyl)phenyl]-5-(2-nitrophenyl)-2-furancarboxamide[no description available]medium10aromatic amide;
furans
2-(8-methoxy-2-methyl-4-oxo-1-quinolinyl)-N-(2-methoxyphenyl)acetamide[no description available]medium10quinolines
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-propan-2-yl-2-furancarboxamide[no description available]medium10quinolines
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone[no description available]medium10stilbenoid
1-cyclohexyl-3-(6-ethoxy-1,3-benzothiazol-2-yl)urea[no description available]medium10benzothiazoles
N-[(3,5-dimethoxyphenyl)methyl]-1-(2,3,4-trimethoxyphenyl)methanamine[no description available]medium10dimethoxybenzene
2-[[5-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-4-oxo-2-phenyl-1-benzopyran-7-yl]oxy]acetic acid tert-butyl ester[no description available]medium10flavones;
tert-butyl ester
ethylenethiourea[no description available]medium10imidazolidines
p-aminosalicylic acid monosodium salt[no description available]medium10organic molecular entity
digoxin[no description available]medium10cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
mecysteine hydrochloride[no description available]medium10alpha-amino acid ester
ethionamide[no description available]medium10pyridines;
thiocarboxamide		antilipemic drug;
antitubercular agent;
fatty acid synthesis inhibitor;
leprostatic drug;
prodrug
2-(2-furanyl)-4-thiazolidinecarboxylic acid[no description available]medium10organonitrogen compound;
organooxygen compound
dihydrosamidine[no description available]medium10
N-(2-methoxycyclohexyl)-3,4-dimethylaniline[no description available]medium10methylbenzene
2-(3,4-dimethylphenyl)-5-ethyl-5-phenyl-1,2,4-triazolidine-3-thione[no description available]medium10methylbenzene
2-[3-oxo-1-[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]-2-piperazinyl]acetic acid propan-2-yl ester[no description available]medium10isopropyl ester;
piperazines
zeranol[no description available]medium10macrolide
monooctanoin[no description available]medium101-monoglyceride;
octanoate ester;
rac-1-monoacylglycerol
trimethoprim[no description available]medium10
4-hydroxy-1-[1-oxo-2-(phenylmethoxycarbonylamino)propyl]-2-pyrrolidinecarboxylic acid[no description available]medium10peptide
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,3-dimethoxyphenyl)acetamide[no description available]medium10dimethoxybenzene
3-acetyl-6-methyl-1H-quinolin-4-one[no description available]medium10quinolines
3-(phenylthio)-1-(1-pyrrolidinyl)-1-propanone[no description available]medium10aryl sulfide
N-(3-chlorophenyl)-5-oxo-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindole-1-carboxamide[no description available]medium10imidazolidines
Anthraniloyllycoctonine[no description available]medium10diterpene alkaloid
N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamide[no description available]medium10aromatic amide
1-[3-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid[no description available]medium10harmala alkaloid
biochanin a[no description available]medium104'-methoxyisoflavones;
7-hydroxyisoflavones		antineoplastic agent;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
prostaglandin b1[no description available]medium10prostaglandins Bhuman metabolite
prostaglandin f1[no description available]medium10prostaglandins Falphahuman metabolite
zearalenone[no description available]medium10macrolide;
resorcinols		fungal metabolite;
mycoestrogen
estriol 17-glucuronide[no description available]medium10steroid saponin
4-hydroxyestradiol[no description available]medium104-hydroxy steroidmetabolite
menatetrenone[no description available]medium10menaquinoneanti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent
dinoprost tromethamine[no description available]medium10organic molecular entity
hydrocortisone valerate[no description available]medium10cortisol ester;
glucocorticoid;
primary alpha-hydroxy ketone;
valerate ester
prostaglandin f2 methyl ester[no description available]medium10prostanoid
2-bromoergocryptine mesylate[no description available]medium10
perhexiline maleate[no description available]medium10
ethisterone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol		drug metabolite;
progestin
nalmefene[no description available]medium10morphinane alkaloid
6alpha-hydroxy-17beta-estradiol[no description available]medium106alpha-hydroxy steroid
desoximetasone[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
cytochalasin b[no description available]medium60cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor
furazolidone[no description available]medium10
nifuroxazide[no description available]medium10benzoic acids
rg 13022[no description available]medium10
styrylquinoline[no description available]medium102-styrylquinoline
kavain[no description available]medium10racemateglycine receptor antagonist
enalapril maleate[no description available]medium10maleate saltantihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
trimebutine maleate salt[no description available]medium10trihydroxybenzoic acid
vincristine sulfate[no description available]medium10
3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-5,7-dihydroxy-2-methyl-1-benzopyran-4-one[no description available]medium10isoflavones
(2R)-2-[[(2R,3R,4R)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-2-[(2S,3R,4S,5S)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]acetic acid[no description available]medium10peptide
phentolamine[no description available]medium10
fendiline hydrochloride[no description available]medium10
nab-365[no description available]medium10hydrochloridebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
dithiazanine iodide[no description available]medium10benzothiazoles;
organic iodide salt		anthelminthic drug;
fluorochrome
sinequan[no description available]medium10dibenzooxazepine
buflomedil hydrochloride[no description available]medium10aromatic ketone
dirithromycin[no description available]medium10macrolide antibioticprodrug
fluphenazine[no description available]medium10
homochlorocyclizine monohydrochloride[no description available]medium10
butoxamine hydrochloride[no description available]medium10
scopolamine hydrobromide[no description available]medium10
emetine hydrochloride[no description available]medium10
6 beta-hydroxycortisol[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
6beta-hydroxy steroid;
C21-steroid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mammalian metabolite;
probe
androst-16-en-3-one[no description available]medium103-oxo steroid;
androstanoid		mammalian metabolite;
pheromone
dihydroouabain[no description available]medium10cardenolide glycosideEC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
radiosensitizing agent
LSM-6455[no description available]medium10peptide ergot alkaloid
estradiol 17-acetate[no description available]medium10steroid ester
(3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione[no description available]medium10pyrrolidines
N-[[3-(2-chlorophenyl)-1-(4-fluorophenyl)-4-pyrazolyl]methyl]-2-(2-pyridinyl)ethanamine[no description available]medium10pyrazoles;
ring assembly
bucladesine[no description available]medium1503',5'-cyclic purine nucleotide
ampicillin sodium[no description available]medium10organic sodium salt
penicillin g potassium[no description available]medium10organic potassium salt
piperacillin sodium[no description available]medium10organic sodium salt
cefoxitin sodium[no description available]medium10organic molecular entity
nafcillin sodium[no description available]medium10organic sodium salt
cefamandole nafate[no description available]medium10organic sodium saltantibacterial drug
sodium diatrizoate[no description available]medium10organic sodium salt;
organoiodine compound		radioopaque medium
estrone sulfate, potassium salt[no description available]medium10
naproxen sodium[no description available]medium10organic sodium saltantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
oxytetracycline, anhydrous[no description available]medium10
acenocoumarol[no description available]medium10C-nitro compound;
hydroxycoumarin;
methyl ketone		anticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
mobic[no description available]medium101,3-thiazoles;
benzothiazine;
monocarboxylic acid amide		analgesic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
mobiflex[no description available]medium10heteroaryl hydroxy compound;
monocarboxylic acid amide;
pyridines;
thienothiazine		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
inosine[no description available]medium100inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
kf38789[no description available]medium10
pralidoxime iodide[no description available]medium10organic iodide salt;
pyridinium salt		cholinergic drug;
cholinesterase reactivator
pralidoxime chloride[no description available]medium10organic chloride salt;
pyridinium salt		cholinergic drug;
cholinesterase reactivator
mrs 3558[no description available]medium10
adenosine diphosphate[no description available]medium120adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
adenosine diphosphate[no description available]medium121adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
adenosine monophosphate[no description available]medium50adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
2-aminopurine[no description available]medium102-aminopurines;
nucleobase analogue		antimetabolite
2,6-diaminopurine[no description available]medium102,6-diaminopurines;
primary amino compound		antineoplastic agent
9-methyladenine[no description available]medium10methyladeninemetabolite
8-azaadenine[no description available]medium10aromatic amine;
nucleobase analogue;
triazolopyrimidines		EC 1.17.3.2 (xanthine oxidase) inhibitor;
Mycoplasma genitalium metabolite
7-methyladenine[no description available]medium10methyladeninemetabolite
2-aminoadenosine[no description available]medium10purine nucleoside
9-(2,3-dihydroxypropyl)adenine[no description available]medium10
2-amino-6-chloropurine[no description available]medium102-aminopurines;
organochlorine compound
guanine[no description available]medium202-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanosine[no description available]medium30guanosines;
purines D-ribonucleoside		fundamental metabolite
hypoxanthine[no description available]medium60nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
9-(2-hydroxy-3-nonyl)adenine[no description available]medium10EHNA
bay 60-7550[no description available]medium10
nsc 65346[no description available]medium10nucleoside analogueprotein kinase inhibitor
coformycin[no description available]medium50coformycinsEC 3.5.4.4 (adenosine deaminase) inhibitor
adefovir[no description available]medium106-aminopurines;
ether;
phosphonic acids		antiviral drug;
DNA synthesis inhibitor;
drug metabolite;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent
adefovir dipivoxil[no description available]medium106-aminopurines;
carbonate ester;
ether;
organic phosphonate		antiviral drug;
DNA synthesis inhibitor;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent;
prodrug
psicofuranine[no description available]medium10psicose derivative;
purine nucleoside
9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine[no description available]medium10
9-(3-hydroxy-2-phosphonomethoxypropyl)-2,6-diaminopurine[no description available]medium10
5-iodotubercidin[no description available]medium70organoiodine compound
angustmycin a[no description available]medium106-aminopurines
n(6)-methyl-2'-deoxyadenosine[no description available]medium10purine 2'-deoxyribonucleoside
pentostatin[no description available]medium210coformycinsantimetabolite;
antineoplastic agent;
Aspergillus metabolite;
bacterial metabolite;
EC 3.5.4.4 (adenosine deaminase) inhibitor
pentostatin[no description available]medium211coformycinsantimetabolite;
antineoplastic agent;
Aspergillus metabolite;
bacterial metabolite;
EC 3.5.4.4 (adenosine deaminase) inhibitor
forodesine[no description available]medium10dihydroxypyrrolidine;
pyrrolopyrimidine
immucillin g[no description available]medium10dihydroxypyrrolidine;
pyrrolopyrimidine
ulodesine[no description available]medium10
adenosine-5'-carboxylic acid[no description available]medium10purine nucleoside
adenosine 5'-carboxamide[no description available]medium10
adenosine 5'-phosphoramidate[no description available]medium10organic phosphoramidateMycoplasma genitalium metabolite
adenosine-5'-(N-propyl)carboxamide[no description available]medium10adenosines;
monocarboxylic acid amide
8-chloroadenosine[no description available]medium590
8-azaadenosine[no description available]medium10N-glycosyl compound
cyclin d1[no description available]medium20
abt-199[no description available]medium10aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
sevoflurane[no description available]medium10ether;
organofluorine compound		central nervous system depressant;
inhalation anaesthetic;
platelet aggregation inhibitor
rocuronium[no description available]medium103alpha-hydroxy steroid;
acetate ester;
androstane;
morpholines;
quaternary ammonium ion;
tertiary amino compound		drug allergen;
muscle relaxant;
neuromuscular agent
valproic acid[no description available]medium10branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
2'-chloro-2'-deoxyadenosine[no description available]medium81
5'-sulfamoyl-2-chloroadenosine[no description available]medium60
ascamycin[no description available]medium50
glutamic acid[no description available]medium90glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
bay 60-6583[no description available]medium10aminopyridine;
aromatic ether;
aryl sulfide;
cyanopyridine;
cyclopropanes;
monocarboxylic acid amide		adenosine A2B receptor agonist;
anti-inflammatory agent;
cardioprotective agent
alpha-aminopyridine[no description available]medium20
8-chloro-cyclic adenosine monophosphate[no description available]medium210
piperidines[no description available]medium50
hexylamine[no description available]medium10primary aliphatic aminemetabolite
8-bromo cyclic adenosine monophosphate[no description available]medium3603',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
hydroxyl radical[no description available]medium20oxygen hydride;
oxygen radical;
reactive oxygen species
1,3,7-trimethylurate[no description available]medium10oxopurinehuman blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
protocatechuic acid[no description available]medium10catechols;
dihydroxybenzoic acid		antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite
selegiline[no description available]medium10selegiline;
terminal acetylenic compound		geroprotector
benserazide[no description available]medium10carbohydrazide;
catechols;
primary alcohol;
primary amino compound		antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
go 6976[no description available]medium10indolocarbazole;
organic heterohexacyclic compound		EC 2.7.11.13 (protein kinase C) inhibitor
tocopherylquinone[no description available]medium10
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
nicardipine[no description available]medium10benzenes;
C-nitro compound;
diester;
dihydropyridine;
methyl ester;
tertiary amino compound
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid[no description available]medium10
iberiotoxin[no description available]medium10
succinic acid[no description available]medium20alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
metformin[no description available]medium10guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
oligomycins[no description available]medium10
fumarates[no description available]medium10butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
cytarabine[no description available]medium61beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
enkephalin, ala(2)-mephe(4)-gly(5)-[no description available]medium20
pyrroles[no description available]medium20pyrrole;
secondary amine
kt 5720[no description available]medium20carboxylic ester;
gamma-lactam;
hemiaminal;
indolocarbazole;
organic heterooctacyclic compound;
semisynthetic derivative;
tertiary alcohol		EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
triazoles[no description available]medium1001,2,3-triazole
cyclosporine[no description available]medium30
prednisone[no description available]medium4111-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug
2-methyltetrahydrofuran[no description available]medium10
1-anilino-8-naphthalenesulfonate[no description available]medium10aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
thioinosine[no description available]medium130
cysteine[no description available]medium10cysteiniumfundamental metabolite
ovalbumin[no description available]medium20
2'-deoxyadenosine triphosphate[no description available]medium102'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
adenosine kinase[no description available]medium120
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid[no description available]medium20arenesulfonic acid;
azobenzenes;
methylpyridines;
monohydroxypyridine;
organic phosphate;
pyridinecarbaldehyde		purinergic receptor P2X antagonist
pyridoxal phosphate[no description available]medium20methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
alpha,beta-methyleneadenosine 5'-triphosphate[no description available]medium110nucleoside triphosphate analogue
3-hydroxyaspartic acid[no description available]medium10amino dicarboxylic acid;
aspartic acid derivative;
C4-dicarboxylic acid;
hydroxy-amino acid
pyrrolidine-2,4-dicarboxylic acid[no description available]medium10
beta-escin[no description available]medium10
glucosamine[no description available]medium10D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
diosgenin[no description available]medium103beta-sterol;
hexacyclic triterpenoid;
sapogenin;
spiroketal		antineoplastic agent;
antiviral agent;
apoptosis inducer;
metabolite
decitabine[no description available]medium102'-deoxyribonucleoside
daunorubicin[no description available]medium21aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
quinazolines[no description available]medium40azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
formaldehyde[no description available]medium20aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
ng-nitroarginine methyl ester[no description available]medium90alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
phenylephrine[no description available]medium80phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
beta-alanine[no description available]medium10amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
2-chloro-atp[no description available]medium20
bryostatin 1[no description available]medium20
bromochloroacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound
calcitriol[no description available]medium30D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
thymidine[no description available]medium80pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
leucine[no description available]medium20amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
formycins[no description available]medium20
formycin b[no description available]medium10formycin
casein kinase ii[no description available]medium20
20-hydroxy-5,8,11,14-eicosatetraenoic acid[no description available]medium10HETE;
hydroxy monocarboxylic acid		human metabolite;
mouse metabolite
8,11,14-eicosatrienoic acid[no description available]medium10fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical
prednisolone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic
sulfinosine[no description available]medium10
penicillamine[no description available]medium10non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
oxadiazoles[no description available]medium10
quinoxalines[no description available]medium40mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
s-nitro-n-acetylpenicillamine[no description available]medium10
9-(2-hydroxy-3-nonyl)adenine[no description available]medium150
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
suramin[no description available]medium20naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
2-methylthio-atp[no description available]medium30
draflazine[no description available]medium10
agar[no description available]medium10
docetaxel anhydrous[no description available]medium10secondary alpha-hydroxy ketone;
tetracyclic diterpenoid		antimalarial;
antineoplastic agent;
photosensitizing agent
5'-adenylyl (beta,gamma-methylene)diphosphonate[no description available]medium40nucleoside triphosphate analogue
lactic acid[no description available]medium402-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
glycogen[no description available]medium50
normorphine[no description available]medium10morphinane alkaloid
tetrodotoxin[no description available]medium150azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
clonidine[no description available]medium180clonidine;
imidazoline
choline[no description available]medium20cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
adenosine 5'-methylenediphosphate[no description available]medium10nucleoside diphosphate analogue
glucagon[no description available]medium50peptide hormone
dihydroxyphenylalanine[no description available]medium20hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
hydrogen carbonate[no description available]medium20carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
chlorine[no description available]medium170halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
dideoxyadenosine[no description available]medium70adenosines;
purine 2',3'-dideoxyribonucleoside		EC 3.5.4.4 (adenosine deaminase) inhibitor;
EC 4.6.1.1 (adenylate cyclase) inhibitor
methoxyhydroxyphenylglycol[no description available]medium10methoxybenzenes;
phenols
isoproterenol[no description available]medium330catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
2',5'-dideoxyadenosine[no description available]medium40deoxyribonucleoside
cyclic gmp[no description available]medium403',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
5'-deoxy-5'-s-isobutylthioadenosine[no description available]medium10
alprostadil[no description available]medium50prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
lanthanum[no description available]medium20f-block element atom;
lanthanoid atom;
scandium group element atom
strontium[no description available]medium10alkaline earth metal atom
8-((4-chlorophenyl)thio)cyclic-3',5'-amp[no description available]medium203',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
aryl sulfide;
organochlorine compound		protein kinase agonist
n-formylmethionine leucyl-phenylalanine[no description available]medium150tripeptide
muscarine[no description available]medium20monosaccharide
fructose 2,6-diphosphate[no description available]medium10D-fructofuranose 2,6-bisphosphatehuman metabolite;
mouse metabolite
methylthioinosine[no description available]medium20purine ribonucleoside;
thiopurine
terbutaline[no description available]medium20phenylethanolamines;
resorcinols		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
sympathomimetic agent;
tocolytic agent
p-aminohippuric acid[no description available]medium10N-acylglycineDaphnia magna metabolite
dinoprostone[no description available]medium110prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
arachidonic acid[no description available]medium60icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
vasoactive intestinal peptide[no description available]medium100
propranolol[no description available]medium40naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
azides[no description available]medium30pseudohalide anionmitochondrial respiratory-chain inhibitor
2-azidoadenosine[no description available]medium10
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
concanavalin a[no description available]medium30
valinomycin[no description available]medium20cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
triphenylmethylphosphonium[no description available]medium10
brimonidine tartrate[no description available]medium20
substance p[no description available]medium30peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
gp 1-515[no description available]medium10
thymidine monophosphate[no description available]medium10thymidine 5'-monophosphatefundamental metabolite
diazobenzenesulfonic acid[no description available]medium10
thymidine 5'-4-nitrophenyl phosphate[no description available]medium10aryl phosphate;
C-nitro compound;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate
guanosine triphosphate[no description available]medium100guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
guanosine 5'-o-(3-thiotriphosphate)[no description available]medium20nucleoside triphosphate analogue
citrulline[no description available]medium20amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
methoxamine[no description available]medium40amphetaminesalpha-adrenergic agonist;
antihypotensive agent
g(m1) ganglioside[no description available]medium60alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide
asialo gm1 ganglioside[no description available]medium60
ferric chloride[no description available]medium10iron coordination entityastringent;
Lewis acid
deoxyribose[no description available]medium20deoxypentosehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
iloprost[no description available]medium30carbobicyclic compound;
monocarboxylic acid;
secondary alcohol		platelet aggregation inhibitor;
vasodilator agent
amphetamine[no description available]medium20primary amine
omega-n-methylarginine[no description available]medium40amino acid zwitterion;
arginine derivative;
guanidines;
L-arginine derivative;
non-proteinogenic L-alpha-amino acid
zatebradine[no description available]medium10benzazepine
e 4031[no description available]medium10sulfonamide
picrotoxin[no description available]medium10
6-cyano-7-nitroquinoxaline-2,3-dione[no description available]medium20quinoxaline derivative
aminopyrine[no description available]medium20pyrazolone;
tertiary amino compound		antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
adenosine diphosphate ribose[no description available]medium50ADP-sugarEscherichia coli metabolite;
mouse metabolite
manganese[no description available]medium30elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
ferrous chloride[no description available]medium10iron coordination entity
sq-23377[no description available]medium20cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite
cobalt[no description available]medium40cobalt group element atom;
metal allergen		micronutrient
cobaltous chloride[no description available]medium20cobalt salt;
inorganic chloride		allergen;
calcium channel blocker;
sensitiser;
two-colour indicator
1,9-dideoxyforskolin[no description available]medium10acetate ester;
labdane diterpenoid;
organic heterotricyclic compound		plant metabolite
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
staurosporine[no description available]medium40ammonium ion derivative
idoxuridine[no description available]medium10organoiodine compound;
pyrimidine 2'-deoxyribonucleoside		antiviral drug;
DNA synthesis inhibitor
isoflurane[no description available]medium30organofluorine compoundinhalation anaesthetic
w 7[no description available]medium10
gallic acid[no description available]medium20trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
metallothionein[no description available]medium20
deoxyglucose[no description available]medium30
sodium fluoride[no description available]medium80fluoride saltmutagen
tetraethylammonium[no description available]medium20quaternary ammonium ion
veratridine[no description available]medium70
adenosine 5'-o-(3-thiotriphosphate)[no description available]medium40nucleoside triphosphate analogue
uridine triphosphate[no description available]medium20pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
kf 17837s[no description available]medium50
biotin[no description available]medium10biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
deoxycytidine[no description available]medium40pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
gemcitabine[no description available]medium20organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic
cycloleucine[no description available]medium30non-proteinogenic alpha-amino acidEC 2.5.1.6 (methionine adenosyltransferase) inhibitor
alanine[no description available]medium20alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
organophosphonates[no description available]medium10divalent inorganic anion;
phosphite ion
glycine[no description available]medium20alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
3,5-dihydroxyphenylglycine[no description available]medium10alpha-amino acid
guanylyl imidodiphosphate[no description available]medium100nucleoside triphosphate analogue
omega-agatoxin iva[no description available]medium30
methionine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
vitamin k semiquinone radical[no description available]medium10
thiobarbituric acid[no description available]medium10barbituratesallergen;
reagent
malondialdehyde[no description available]medium10dialdehydebiomarker
purine[no description available]medium10purine
n-(1-methyl-2-phenylethyl)adenosine[no description available]medium50
dactinomycin[no description available]medium10actinomycinmutagen
ucn 1028 c[no description available]medium10
nitrites[no description available]medium30monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
potassium chloride[no description available]medium60inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
mycophenolic acid[no description available]medium202-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
gramicidin a[no description available]medium10
barium[no description available]medium50alkaline earth metal atom;
elemental barium
quipazine[no description available]medium10piperazines;
pyridines
p(1),p(5)-di(adenosine-5'-)pentaphosphate[no description available]medium10organophosphate oxoanion
6-nitroquipazine[no description available]medium10nitro compound;
quinolines
lithium[no description available]medium30alkali metal atom
pilocarpine[no description available]medium40pilocarpineantiglaucoma drug
adenosine-3',5'-cyclic phosphorothioate[no description available]medium10nucleoside 3',5'-cyclic phosphorothioate
cardiovascular agents[no description available]medium10
midazolam[no description available]medium10imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
thiopental[no description available]medium10barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
nicorandil[no description available]medium10nitrate ester;
pyridinecarboxamide		potassium channel opener;
vasodilator agent
carbonyl cyanide m-chlorophenyl hydrazone[no description available]medium10hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore
apyrase[no description available]medium21
propidium[no description available]medium20phenanthridines;
quaternary ammonium ion		fluorochrome;
intercalator
proline[no description available]medium10amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
cytidylyl-3',5'-adenosine[no description available]medium10nucleoside analogue;
purines
barium chloride[no description available]medium10barium salt;
inorganic chloride		potassium channel blocker
thiazolyl blue[no description available]medium10organic bromide saltcolorimetric reagent;
dye
thiazoles[no description available]medium101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
5'-chloro-5'-deoxyadenosine[no description available]medium20adenosines
homocysteine[no description available]medium20amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
2-(4-(2-(2-((4-aminophenyl)methylcarbonylamino)ethylaminocarbonyl)ethyl)phenyl)ethylamino-5'-n-ethylcarboxamidoadenosine[no description available]medium10
dinoprost[no description available]medium30monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
angiotensin ii[no description available]medium10amino acid zwitterion;
angiotensin II		human metabolite
angiotensin ii, des-asp(1)-des-arg(2)-ile(5)-[no description available]medium10organic molecular entity
9-arabinofuranosylguanine[no description available]medium10beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
DNA synthesis inhibitor
cytosine[no description available]medium10aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
troxacitabine[no description available]medium10carbohydrate derivative;
nucleobase-containing molecular entity
pirenzepine[no description available]medium10pyridobenzodiazepineanti-ulcer drug;
antispasmodic drug;
muscarinic antagonist
4-diphenylacetoxy-1,1-dimethylpiperidinium[no description available]medium10quaternary ammonium ioncholinergic antagonist;
muscarinic antagonist
interleukin-8[no description available]medium10
midostaurin[no description available]medium10benzamides;
gamma-lactam;
indolocarbazole;
organic heterooctacyclic compound		antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
neuropeptide y[no description available]medium10
gastrins[no description available]medium10
tubocurarine[no description available]medium10bisbenzylisoquinoline alkaloiddrug allergen;
muscle relaxant;
nicotinic antagonist
carbostyril[no description available]medium10monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
rifamycins[no description available]medium10
amsacrine[no description available]medium11acridines;
aromatic ether;
sulfonamide		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
fura-2[no description available]medium10
omega-conotoxin (conus magus)[no description available]medium30
glycerol[no description available]medium20alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
aminoimidazole carboxamide[no description available]medium10aminoimidazole;
monocarboxylic acid amide		mouse metabolite
acadesine[no description available]medium101-ribosylimidazolecarboxamide;
aminoimidazole;
nucleoside analogue		antineoplastic agent;
platelet aggregation inhibitor
3-deazaaristeromycin[no description available]medium10
dextroamphetamine[no description available]medium201-phenylpropan-2-amineadrenergic agent;
adrenergic uptake inhibitor;
dopamine uptake inhibitor;
dopaminergic agent;
neurotoxin;
sympathomimetic agent
adenylyl imidodiphosphate[no description available]medium10adenosine 5'-phosphate
rubidium[no description available]medium20alkali metal atom
inositol[no description available]medium30cyclitol;
hexol
1-oleoyl-2-acetylglycerol[no description available]medium201,2-diglyceride
enkephalin, leucine[no description available]medium20pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
dynorphins[no description available]medium10
neplanocin a[no description available]medium10
tiazofurin[no description available]medium101,3-thiazoles;
C-glycosyl compound;
monocarboxylic acid amide		antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
prodrug
3-deazaguanosine[no description available]medium10
3-deazaguanine[no description available]medium10
alpidem[no description available]medium10imidazoles
zolpidem[no description available]medium10imidazopyridinecentral nervous system depressant;
GABA agonist;
sedative
edetic acid[no description available]medium20ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
barbital[no description available]medium10barbituratesdrug allergen
flunitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes		anxiolytic drug;
GABAA receptor agonist;
sedative
nad[no description available]medium30organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
dihydropyridines[no description available]medium20
substance p, pro(9)-[no description available]medium10
trypan blue[no description available]medium10
nitroglycerin[no description available]medium20nitroglycerolexplosive;
muscle relaxant;
nitric oxide donor;
prodrug;
tocolytic agent;
vasodilator agent;
xenobiotic
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
cgp 35348[no description available]medium10
atrial natriuretic factor[no description available]medium10polypeptide
8-bromocyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
organobromine compound		muscle relaxant;
protein kinase G agonist
zk 91296[no description available]medium10
ephedrine[no description available]medium10phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
flupenthixol[no description available]medium10thioxanthenes
demeclocycline[no description available]medium10
minocycline[no description available]medium10
masoprocol[no description available]medium10nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite
bradykinin[no description available]medium30oligopeptidehuman blood serum metabolite;
vasodilator agent
hexamethonium[no description available]medium20quaternary ammonium salt
n-n-propylnorapomorphine[no description available]medium10
2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one[no description available]medium10
pituitrin[no description available]medium10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine[no description available]medium202-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
tert-butyl alcohol[no description available]medium10tertiary alcoholhuman xenobiotic metabolite
1-butanol[no description available]medium10alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
erythromycin[no description available]medium10cyclic ketone;
erythromycin
2,4-dinitrophenol[no description available]medium10dinitrophenolallergen;
antiseptic drug;
bacterial xenobiotic metabolite;
geroprotector;
oxidative phosphorylation inhibitor
zithromax[no description available]medium10macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic
monensin[no description available]medium10cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid[no description available]medium10
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]medium10stilbenoid
hydralazine[no description available]medium20azaarene;
hydrazines;
ortho-fused heteroarene;
phthalazines		antihypertensive agent;
vasodilator agent
oxotremorine[no description available]medium40N-alkylpyrrolidine
cytidine[no description available]medium10cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
idazoxan[no description available]medium10benzodioxine;
imidazolines		alpha-adrenergic antagonist
d-ala(2),mephe(4),met(0)-ol-enkephalin[no description available]medium10
8-cyclopropyltheophylline[no description available]medium10
capsaicin[no description available]medium10capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
pumiliotoxin b[no description available]medium10
ru 24926[no description available]medium10
sulotroban[no description available]medium10
epidermal growth factor[no description available]medium10
enkephalin, leucine-2-alanine[no description available]medium10
prostaglandin d2[no description available]medium10prostaglandins Dhuman metabolite;
mouse metabolite
aluminum[no description available]medium10boron group element atom;
elemental aluminium;
metal atom
aluminum chloride[no description available]medium10aluminium coordination entityLewis acid
alprazolam[no description available]medium10organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
u 43465f[no description available]medium10
methionyl-leucyl-phenylalanine[no description available]medium10oligopeptide
s-adenosylhomocysteine[no description available]medium10adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide		cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite
glucose, (beta-d)-isomer[no description available]medium20D-glucopyranoseepitope;
mouse metabolite
9-(tetrahydro-2-furyl)-adenine[no description available]medium10
phosphorylcholine[no description available]medium10phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
preclamol[no description available]medium10
diazooxonorleucine[no description available]medium10amino acid zwitterion;
diazo compound;
ketone;
non-proteinogenic L-alpha-amino acid		analgesic;
antibacterial agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
bacterial metabolite;
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor;
EC 3.5.1.2 (glutaminase) inhibitor;
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor;
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor;
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor;
glutamine antagonist
glutaminase[no description available]medium10
benzeneboronic acid[no description available]medium10boronic acids
methanol[no description available]medium10alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
hydrochloric acid[no description available]medium10chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
vanadium[no description available]medium10elemental vanadium;
vanadium group element atom		micronutrient
vanadates[no description available]medium10trivalent inorganic anion;
vanadium oxoanion		EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
phorbols[no description available]medium20diterpene;
terpenoid fundamental parent
metiamide[no description available]medium10imidazoles
arginine vasopressin[no description available]medium10vasopressincardiovascular drug;
hematologic agent;
mitogen
6-fluoronorepinephrine[no description available]medium10catechols
phosphatidylcholines[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine
aldosterone[no description available]medium1011beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
amiloride[no description available]medium10aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker
picibanil[no description available]medium10penicillinate anion
phosphoric acid, trisodium salt[no description available]medium10sodium phosphate
3'-o-(3-(n-(4-azido-2-nitrophenyl)amino)propionyl)adenosine-5'-triphosphate[no description available]medium20
chlormethiazole[no description available]medium10thiazoles
mioflazine[no description available]medium10
fk 156[no description available]medium10
diaminopimelic acid[no description available]medium102,6-diaminopimelic acid;
amino acid zwitterion		Escherichia coli metabolite
fr 41565[no description available]medium10
urethane[no description available]medium10carbamate esterfungal metabolite;
mutagen
cyanides[no description available]medium30pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
aminooxyacetic acid[no description available]medium10amino acid;
hydroxylamines;
monocarboxylic acid		anticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
nootropic agent
amobarbital[no description available]medium10barbiturates
s-adenosylmethionine[no description available]medium10organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
triiodothyronine[no description available]medium10tetrahydrothiophenes;
thiolactone		human metabolite
mitomycin[no description available]medium10mitomycinalkylating agent;
antineoplastic agent
iodoacetic acid[no description available]medium10haloacetic acid;
organoiodine compound		alkylating agent
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone[no description available]medium10dichlorobenzene;
differentiation-inducing factor;
monomethoxybenzene;
resorcinols		eukaryotic metabolite;
signalling molecule
isomethyleugenol[no description available]medium40isomethyleugenol
fomesafen[no description available]medium10aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
guaifenesin[no description available]medium10methoxybenzenes
2-[6-(cyclohexylamino)-9-purinyl]-5-(hydroxymethyl)oxolane-3,4-diol[no description available]low00purine nucleoside
n-allyladenosine[no description available]low00purine nucleoside
1,7-dimethylguanosine[no description available]low00purine nucleoside
8-methyladenosine[no description available]low00purine nucleoside
6-thioguanosine[no description available]low00purine nucleoside
5-(6-aminopurin-9-yl)-N-ethyl-3,4-dihydroxy-2-oxolanecarboxamide[no description available]low00purine nucleoside
nelarabine[no description available]low00beta-D-arabinoside;
monosaccharide derivative;
purine nucleoside		antineoplastic agent;
DNA synthesis inhibitor;
prodrug
(2R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol[no description available]low00purine nucleoside
n-((1s,trans)-2-hydroxycyclopentyl)adenosine[no description available]low00purine nucleoside
ver 155008[no description available]low00purine nucleoside
8-hydroxyguanosine[no description available]low00purine nucleoside
8-bromoguanosine[no description available]low00purine nucleoside
ConditionIndicatedRelationship StrengthStudiesTrials
A-V Dissociation0low10
Abnormalities, Autosome0low10
Abnormalities, Chromosomal0low10
Abnormalities, Chromosome0low10
Abnormalities, Congenital0low10
Abnormalities, Drug-Induced0low10
Absence Seizure0low200
Absence Seizures0low200
Absence Status0low20
Ache0low10
Acquired Autoimmune Hemolytic Anemia0low30
Acquired Immune Deficiency Syndrome0low10
Acquired Immuno-Deficiency Syndrome0low10
Acquired Immunodeficiency Syndrome0low10
Acute Brain Injuries0low30
Acute Confusional Senile Dementia0low10
Acute Disease0medium52
Acute Edematous Pancreatitis0low10
Acute Hemolytic Transfusion Reaction0low10
Acute Lymphoid Leukemia0medium32
Acute Myelogenous Leukemia0medium21
Acute Myeloid Leukemia0medium21
Acute Myeloid Leukemia with Maturation0medium21
Acute Myeloid Leukemia without Maturation0medium21
Acute Pancreatitis0low10
Acute Respiratory Distress Syndrome0low10
Adenocarcinoma0low40
Adenocarcinoma Of Kidney0low10
Adenocarcinoma of Lung0low10
Adenocarcinoma, Basal Cell0low40
Adenocarcinoma, Granular Cell0low40
Adenocarcinoma, Mucinous0low10
Adenocarcinoma, Oxyphilic0low40
Adenocarcinoma, Renal0low10
Adenocarcinoma, Renal Cell0low10
Adenocarcinoma, Tubular0low40
Adenoma, Malignant0low40
Adenosis of Breast0low10
Adrenal Cancer0low90
Adrenal Gland Cancer0low90
Adrenal Gland Neoplasms0low90
Adrenal Neoplasm0low90
Adult Respiratory Distress Syndrome0low10
African Sleeping Sickness0low10
African Trypanosomiasis0low10
Aggression0low10
Aging0low30
AIDS0low10
Airflow Obstruction, Chronic0low10
Airway Remodeling0low10
Airway Remodelling0low10
Airway Wall Remodelling0low10
Alcohol Withdrawal Seizures0low10
Alcohol Withdrawal-Induced Major Motor Seizure0low10
Alcohol Withdrawal-Induced Seizure0low10
Alcohol Withdrawal-Induced Status Epilepticus0low10
Alcohol-Related Seizures0low10
ALL, Childhood0medium32
Alloxan Diabetes0low30
ALS - Amyotrophic Lateral Sclerosis0low10
Alzheimer Dementia0low10
Alzheimer Disease0low10
Alzheimer Disease, Early Onset0low10
Alzheimer Disease, Late Onset0low10
Alzheimer Sclerosis0low10
Alzheimer Syndrome0low10
Alzheimer Type Senile Dementia0low10
Alzheimer-Type Dementia (ATD)0low10
Alzheimer's Disease0low10
Alzheimer's Disease, Focal Onset0low10
Alzheimer's Diseases0low10
Amyotrophic Lateral Sclerosis0low10
Amyotrophic Lateral Sclerosis With Dementia0low10
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 10low10
Amyotrophic Lateral Sclerosis, Guam Form0low10
Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam0low10
Anaplastic Astrocytoma0low40
Anemia0low10
Anemia, Fanconi0low10
Anemia, Hemolytic, Autoimmune0low30
Anemia, Hemolytic, Cold Antibody0low30
Anemia, Hemolytic, Idiopathic Acquired0low30
Anesthesia0low30
Ankylosing Vertebral Hyperostosis with Tylosis0low10
ANLL0medium21
Anochlesia0low10
Anoxemia0low50
Anoxia0low50
Anoxia-Ischemia, Brain0low20
Anoxia-Ischemia, Cerebral0low20
Anoxia, Brain0low20
Anoxia, Cerebral0low20
Anoxic Brain Damage0low20
Anoxic Encephalopathy0low20
Anoxic-Ischemic Encephalopathy0low20
Anterior Circulation Transient Ischemic Attack0low10
Anti-MuSK Myasthenia Gravis0low10
Antibody Deficiency Syndrome0medium11
Anxiety0low10
Aplasia Pure Red Cell0low10
Apoplexy0low10
ARDS, Human0low10
Arthritis, Rheumatoid0low10
Asthma0low30
Asthma, Bronchial0low30
Asthmatic Airway Remodeling0low10
Asthmatic Airway Remodelling0low10
Asthmatic Airway Wall Remodeling0low10
Asthmatic Airway Wall Remodelling0low10
Astrocytoma0low40
Astrocytoma, Grade I0low40
Astrocytoma, Grade II0low40
Astrocytoma, Grade III0low40
Astrocytoma, Protoplasmic0low40
Astrocytoma, Subependymal Giant Cell0low40
Astroglioma0low40
Atonic Absence Seizure0low200
Atonic Absence Seizures0low200
Atonic Seizure0low200
Atonic Seizures0low200
Atrioventricular Dissociation0low10
Audiogenic Epilepsy0low10
Aura0low70
Auriculo-Ventricular Dissociation0low10
Autoimmune Haemolytic Anaemia0low30
Autoimmune Hemolytic Anemia0low30
Autoimmune Thrombocytopenia0low10
Autoimmune Thrombocytopenic Purpura0low10
Autonomic Dysfunction, Paraneoplastic0low10
Autosome Abnormalities0low10
Awakening Epilepsy0low70
B-Cell Chronic Lymphocytic Leukemia0medium214
B-Cell Leukemia0low10
B-Cell Leukemia, Chronic0medium214
B-Cell Malignancy, Low-Grade0medium214
B-Lymphocytic Leukemia0low10
B-Lymphocytic Leukemia, Chronic0medium214
B16 Melanoma0low20
Bacterial Disease0medium11
Bacterial Infection0medium11
Bacterial Infections0medium11
Bacterial Pneumonia0low10
Benign Neoplasms0low40
Benign Neoplasms, Brain0low20
Birth Defects0low10
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Blastocyst Disintegration0low10
Bleeding0low30
Blood Clot0low30
Blood Diseases0low10
Blood Poisoning0low10
Blood Pressure, High0low40
Blood Pressure, Low0low30
Blood Transfusion-Associated Adverse Reactions0low10
Bloodstream Infection0low10
Body Weight0low40
Bone Cancer0low10
Bone Loss, Osteoclastic0low40
Bone Marrow Diseases0medium11
Bone Neoplasms0low10
Bone Resorption0low40
Brain Anoxia0low20
Brain Anoxia-Ischemia0low20
Brain Cancer0low20
Brain Concussion0low10
Brain Damage, Chronic0low10
Brain Hypoxia0low20
Brain Hypoxia-Ischemia0low20
Brain Injuries0low30
Brain Injuries, Acute0low30
Brain Injuries, Focal0low30
Brain Ischemia0low40
Brain Ischemia-Anoxia0low20
Brain Ischemia-Hypoxia0low20
Brain Lacerations0low30
Brain Metastases0low20
Brain Neoplasm, Primary0low20
Brain Neoplasms0low20
Brain Neoplasms, Benign0low20
Brain Neoplasms, Malignant0low20
Brain Neoplasms, Malignant, Primary0low20
Brain Neoplasms, Primary Malignant0low20
Brain Stem Ischemia, Transient0low10
Brain Stem Transient Ischemic Attack0low10
Brain TIA0low10
Brain Tumor, Primary0low20
Brain Tumor, Recurrent0low20
Brain Tumors0low20
Brainstem Ischemia, Transient0low10
Brainstem Transient Ischemic Attack0low10
Breast Cancer0low40
Breast Carcinoma0low40
Breast Dysplasia0low10
Breast Neoplasms0low40
Breast Tumors0low40
Bright Disease0low20
Brill-Symmers Disease0medium21
Bronchial Asthma0low30
Calcification, Pathologic0low20
Calcinosis0low20
Calcinosis, Tumoral0low20
Cancer0low40
Cancer of Bladder0low10
Cancer of Bone0low10
Cancer of Brain0low20
Cancer of Breast0low40
Cancer of Cervix0low10
Cancer of Colon0low30
Cancer of Head0low10
Cancer of Head and Neck0low10
Cancer of Kidney0low10
Cancer of Liver0low30
Cancer of Lung0low100
Cancer of Neck0low10
Cancer of Ovary0low10
Cancer of Pancreas0low10
Cancer of Prostate0low40
Cancer of Skin0low10
Cancer of Spleen0low30
Cancer of Stomach0low20
Cancer of the Adrenal Gland0low90
Cancer of the Bladder0low10
Cancer of the Bone0low10
Cancer of the Brain0low20
Cancer of the Breast0low40
Cancer of the Cervix0low10
Cancer of the Colon0low30
Cancer of the Head0low10
Cancer of the Head and Neck0low10
Cancer of the Kidney0low10
Cancer of the Liver0low30
Cancer of the Lung0low100
Cancer of the Neck0low10
Cancer of the Ovary0low10
Cancer of the Pancreas0low10
Cancer of the Prostate0low40
Cancer of the Skin0low10
Cancer of the Spleen0low30
Cancer of the Stomach0low20
Cancer of the Thyroid0low20
Cancer of the Uterine Cervix0low10
Cancer of Thyroid0low20
Cancer, Hepatocellular0low30
Cancer, Second Primary0medium41
Candida Infection0low20
Candidiasis0low20
Carcinoma, Colloid0low10
Carcinoma, Cribriform0low40
Carcinoma, Epidermoid0low10
Carcinoma, Granular Cell0low40
Carcinoma, Hepatocellular0low20
Carcinoma, Hypernephroid0low10
Carcinoma, Lewis Lung0low20
Carcinoma, Mucinous0low10
Carcinoma, Neuroendocrine0low10
Carcinoma, Non-Small Cell Lung0low10
Carcinoma, Non-Small-Cell Lung0low10
Carcinoma, Planocellular0low10
Carcinoma, Renal Cell0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Tubular0low40
Cardiac Arrest, Sudden0low10
Cardiac Failure0low10
Cardiac Hypertrophy0low20
Cardiac Remodeling, Ventricular0low10
Cardiac Sudden Death0low10
Cardiomegaly0low20
Cardiometabolic Syndrome0low20
Cardiovascular Diseases0low10
Cardiovascular Stroke0low50
Carotid Circulation Transient Ischemic Attack0low10
Catalepsy0low10
Cell Transformation, Neoplastic0low10
Cell Transformation, Viral0low20
Cells, Neoplasm Circulating0low10
Cerea Flexibilitas0low10
Cerebral Anoxia0low20
Cerebral Anoxia-Ischemia0low20
Cerebral Astrocytoma0low40
Cerebral Concussion0low10
Cerebral Hypoxia0low20
Cerebral Hypoxia-Ischemia0low20
Cerebral Ischemia0low40
Cerebral Ischemia-Anoxia0low20
Cerebral Ischemia-Hypoxia0low20
Cerebral Ischemia, Transient0low10
Cerebral Stroke0low10
Cerebrovascular Accident0low10
Cerebrovascular Accident, Acute0low10
Cerebrovascular Apoplexy0low10
Cerebrovascular Stroke0low10
Cervical Cancer0low10
Cervical Neoplasms0low10
Cervix Cancer0low10
Cervix Neoplasms0low10
Charcot Disease0low10
Childhood Cerebral Astrocytoma0low40
Chromophil Renal Cell Carcinoma0low10
Chromophobe Renal Cell Carcinoma0low10
Chromosomal Aberrations0low10
Chromosome Aberrations0low10
Chromosome Abnormalities0low10
Chromosome Deletion0low10
Chronic Airflow Obstruction0low10
Chronic Cystic Mastitis0low10
Chronic Disease0low10
Chronic Encephalopathy0low10
Chronic Illness0low10
Chronic Lung Injury0low10
Chronic Lymphocytic Leukemia0medium214
Chronic Obstructive Airway Disease0low10
Chronic Obstructive Lung Disease0low10
Chronic Obstructive Pulmonary Disease0low10
Chronic Obstructive Pulmonary Diseases0low10
Chronically Ill0low10
Circulating Cells, Neoplasm0low10
Circulating Neoplastic Cells0low10
Circulating Tumor Cells0low10
Cirrhosis0low20
Clasp-Knife Spasticity0low10
Clear Cell Renal Carcinoma0low10
Clear Cell Renal Cell Carcinoma0low10
Clonic Seizure0low200
Clonic Seizures0low200
COAD0low10
Cold Agglutinin Disease0low30
Cold Antibody Disease0low30
Cold Antibody Hemolytic Anemia0low30
Collecting Duct Carcinoma0low10
Collecting Duct Carcinoma (Kidney)0low10
Collecting Duct Carcinoma of the Kidney0low10
Colon Cancer0low30
Colon Neoplasms0low30
Colonic Cancer0low30
Colonic Neoplasms0low30
Commotio Cerebri0low10
Complex Partial Epilepsy0low10
Complex Partial Seizure0low200
Complex Partial Seizure Disorder0low10
Complex Partial Seizures0low200
Complex Partial Status Epilepticus0low20
Concussion, Intermediate0low10
Concussion, Mild0low10
Concussion, Severe0low10
Concussive Convulsion0low10
Congenital Abnormalities0low10
Congenital Defects0low10
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Congestive Heart Failure0low10
Contact Dermatitis0low10
Conus Medullaris Syndrome0low10
Convulsion0low200
Convulsion, Non-Epileptic0low200
Convulsions0low200
Convulsive Seizure0low200
Convulsive Seizures0low200
COPD0low10
Crescendo Transient Ischemic Attacks0low10
Cryoglobulinemia0low10
Cryptogenic Partial Complex Epilepsy0low10
Cursive Epilepsy0low10
Cutaneous T-Cell Lymphoma0low20
CVA (Cerebrovascular Accident)0low10
Cystic Breast Disease0low10
Cystic Disease of Breast0low10
Cystic Fibrosis0low30
Cystic Fibrosis of Pancreas0low30
Cytogenetic Aberrations0low10
Cytogenetic Abnormalities0low10
Cytomegalic Inclusion Disease0low10
Cytomegalovirus Infections0low10
Death, Sudden, Cardiac0low10
Decerebrate Posturing0low10
Decerebrate State0low10
Decision Making Reflex Epilepsy0low10
Decorticate Rigidity0low10
Decorticate State0low10
Defects, Congenital0low10
Deficiency Syndrome, Immunologic0medium11
Deficiency Syndromes, Antibody0medium11
Deficiency Syndromes, Immunologic0medium11
Deficiency, Oxygen0low50
Deformities0low10
Delayed Hemolytic Transfusion Reaction0low10
Delayed Serologic Transfusion Reaction0low10
Dementia With Amyotrophic Lateral Sclerosis0low10
Dementia, Alzheimer Type0low10
Dementia, Presenile0low10
Dementia, Primary Senile Degenerative0low10
Dementia, Senile0low10
Depression, Endogenous0low10
Depression, Neurotic0low10
Depression, Unipolar0low10
Depressive Disorder0low10
Depressive Syndrome0low10
Dermatitis Venenata0low10
Dermatitis, Contact0low10
Destombes-Rosai-Dorfman Syndrome0low10
Diabetes Mellitus, Experimental0low30
Diarrhea0low10
Diathesis0low10
Diffuse Idiopathic Skeletal Hyperostosis0low10
Diffuse Lymphocytic Lymphoma, Poorly-Differentiated0low30
Diffuse Mixed Small and Large Cell Lymphoma0medium73
Diffuse Mixed-Cell Lymphoma0medium73
Diffuse Small Cleaved-Cell Lymphoma0medium73
Diffuse Undifferentiated Lymphoma0medium73
Diffuse Well-Differentiated Lymphocytic Lymphoma0medium214
Diplopia0low10
Diplopia, Cortical0low10
Diplopia, Horizontal0low10
Diplopia, Intermittent0low10
Diplopia, Monocular0low10
Diplopia, Refractive0low10
Diplopia, Unilateral0low10
Diplopia, Vertical0low10
Disease Exacerbation0low10
Disease Models, Animal0low110
Disease Progression0low10
Disease Susceptibility0low10
Disease, Pulmonary0low10
Diseases, Pulmonary0low10
Disintegration of Blastocyst0low10
Disintegration of Embryo0low10
Disorder, Complex Partial Seizures0low10
Disrupted In B-Cell Malignancy0medium214
Double Vision0low10
Drug Withdrawal Symptoms0low20
Drug-Induced Abnormalities0low10
Duncan Disease0low50
Duncan's Syndrome0low50
Dysmetabolic Syndrome X0low20
Dysmyelopoietic Syndromes0low10
E coli Infections0low10
E. coli Infection0low10
Early Onset Alzheimer Disease0low10
Early Post-Traumatic Seizures0low10
Eating-Induced Epilepsy0low10
Eczema, Contact0low10
Electrolytes0low20
Embolic Tumor Cells0low10
Embolism, Tumor0low10
Embryo Death0low10
Embryo Disintegration0low10
Embryo Loss0low10
Embryo Resorption0low10
Encephalopathy, Anoxic-Ischemic0low20
Encephalopathy, Chronic0low10
Encephalopathy, Hypoxic0low20
Encephalopathy, Hypoxic-Ischemic0low20
Encephalopathy, Ischemic0low40
Endotoxemia0low10
Enlarged Heart0low20
Enlarged Spleen0medium21
Eosinophilia0low10
Eosinophilia, Tropical0low10
Epilepsy0low70
Epilepsy, Complex Partial0low10
Epilepsy, Cryptogenic0low70
Epilepsy, Cryptogenic, Partial Complex0low10
Epilepsy, Photogenic0low10
Epilepsy, Post-Traumatic0low10
Epilepsy, Psychic Equivalent0low10
Epilepsy, Psychomotor0low10
Epilepsy, Reading0low10
Epilepsy, Reflex0low10
Epilepsy, Symptomatic, Partial Complex0low10
Epilepsy, Traumatic0low10
Epileptic Seizure0low200
Epileptic Seizures0low200
Epstein-Barr Virus Infection, Familial Fatal0low50
Epstein-Barr Virus-Induced Lymphoproliferative Disease In Males0low50
Erythrocyte Aplasia0low10
Escherichia coli Infections0low10
Experimental Diabetes Mellitus0low30
Experimental Hepatoma0low40
Experimental Hepatomas0low40
Experimental High Pressure Neurological Syndrome0low10
Experimental Liver Neoplasms0low40
Experimental Lung Inflammation0low10
Experimental Mammary Neoplasms0low10
Experimental Melanoma0low20
Experimental Melanomas0low20
Experimental Neoplasms0low10
Extramedullary Spinal Cord Compression0low10
Facial Palsy0low10
Facial Palsy, Lower Motor Neuron0low10
Facial Palsy, Upper Motor Neuron0low10
Facial Paralysis0low10
Facial Paralysis, Central0low10
Facial Paralysis, Peripheral0low10
Facial Paresis0low10
Familial Alzheimer Disease (FAD)0low10
Familial Fatal Epstein-Barr Infection0low50
Familial Waldenstrom's Macroglobulinaemia0low10
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Fatty Liver0low10
Febrile Non-Hemolytic Transfusion Reaction0low10
Fetal Anomalies0low10
Fetal Death0low10
Fetal Demise0low10
Fetal Malformations0low10
Fetal Mummification0low10
Fever, Zika0low10
Fibrillary Astrocytoma0low40
Fibrocystic Breast Disease0low10
Fibrocystic Changes of Breast0low10
Fibrocystic Disease of Breast0low10
Fibrocystic Disease of Pancreas0low30
Fibrocystic Mastopathy0low10
Fibrosarcoma0low10
Fibrosis0low20
Flexibility, Waxy0low10
Focal Brain Injuries0low30
Focal Onset Alzheimer's Disease0low10
Follicular Large-Cell Lymphoma0medium21
Follicular Lymphoma0medium21
Follicular Lymphoma, Giant0medium21
Follicular Lymphoma, Grade 10medium21
Follicular Lymphoma, Grade 20medium21
Follicular Lymphoma, Grade 30medium21
Follicular Mixed-Cell Lymphoma0medium21
Forestier Disease0low10
Forestier-Rotes Disease0low10
Forestier's Disease0low10
Fungemia0low10
Gastric Cancer0low20
Gastric Cancer, Familial Diffuse0low20
Gastric Neoplasms0low20
Gastric Ulcer0low10
Gastroduodenal Ulcer0low10
Gehrig's Disease0low10
Gemistocytic Astrocytoma0low40
Generalized Absence Seizure0low200
Generalized Absence Seizures0low200
Generalized Convulsive Status Epilepticus0low20
Generalized Tonic-Clonic Seizures0low200
Germinoblastoma0low90
Giant Follicular Lymphoma0medium21
Glial Cell Tumors0low30
Glioma0low30
Glioma, Astrocytic0low40
Glomerulonephritis0low20
Grand Mal Status Epilepticus0low20
Granulocytic Leukemia0medium52
Granulocytic Leukemia, Chronic0low10
Granulomatous Slack Skin0low20
Grawitz Tumor0low10
Guam Disease0low10
Guam Form of Amyotrophic Lateral Sclerosis0low10
Hairy Cell Leukemia0medium353
Hand-Schu00FCller-Christian Disease0medium21
Hand-Schu00FCller-Christian Syndrome0medium21
Hand-Schueller-Christian Disease0medium21
Hand-Schueller-Christian Syndrome0medium21
Harding Passey Melanoma0low20
Hashimoto-Pritzger Disease0medium21
Head and Neck Cancer0low10
Head and Neck Neoplasm0low10
Head and Neck Neoplasms0low10
Head Cancer0low10
Head Neoplasm0low10
Head Neoplasms0low10
Head, Neck Neoplasms0low10
Heart Attack0low50
Heart Block0low10
Heart Decompensation0low10
Heart Disease, Ischemic0low10
Heart Enlargement0low20
Heart Failure0low10
Heart Failure, Congestive0low10
Heart Failure, Left-Sided0low10
Heart Failure, Right-Sided0low10
Heart Hypertrophy0low20
Hematologic Diseases0low10
Hematologic Malignancies0low10
Hematologic Malignancy0low10
Hematologic Neoplasms0low10
Hematological Diseases0low10
Hematological Malignancies0low10
Hematological Neoplasms0low10
Hematopoetic Myelodysplasia0low10
Hematopoietic Malignancies0low10
Hematopoietic Neoplasms0low10
Hemifacial Paralysis0low10
Hemolytic Anemia, Autoimmune0low30
Hemolytic Transfusion Reaction0low10
Hemorrhage0low30
Hepatic Cancer0low30
Hepatic Neoplasms0low30
Hepatitis C0low10
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted0low10
Hepatocellular Cancer0low30
Hepatocellular Carcinoma0low20
Hepatoma0low20
Hepatoma, Experimental0low40
Hepatoma, Morris0low40
Hepatoma, Novikoff0low40
Hepatomas, Experimental0low40
Herpes Simplex0low10
Herpes Simplex Virus Infection0low10
High Pressure Nervous Syndrome0low10
High Pressure Neural Syndrome0low10
High Pressure Neurological Syndrome0low10
High Pressure Neurological Syndrome, Experimental0low10
Histiocytic Lymphoma, Nodular0medium21
Histiocytosis X0medium21
Histiocytosis-X0medium21
Histiocytosis, Generalized0medium21
Histiocytosis, Langerhans-Cell0medium21
Histiocytosis, Sinus0low10
HIV0low20
HPNS0low10
Human Mammary Carcinoma0low40
Hypercapnia0low10
Hyperglycemia0low10
Hyperglycemia, Postprandial0low10
Hypernephroma0low10
Hyperostosis, Diffuse Idiopathic Skeletal0low10
Hyperplasia0low10
Hypersensitivity, Contact0low10
Hypertension0low40
Hypertrophy, Left Ventricular0low10
Hypesthesia0low10
Hypesthesia, Tactile0low10
Hypesthesia, Thermal0low10
Hypoesthesia0low10
Hypotension0low30
Hypotension, Vascular0low30
Hypotensive Transfusion Reaction0low10
Hypothermia0low10
Hypothermia, Accidental0low10
Hypoxemia0low50
Hypoxia0low50
Hypoxia-Ischemia, Brain0low20
Hypoxia-Ischemia, Cerebral0low20
Hypoxia, Brain0low20
Hypoxia, Cerebral0low20
Hypoxic Brain Damage0low20
Hypoxic Encephalopathy0low20
Hypoxic-Ischemic Encephalopathy0low20
Idiopathic Autoimmune Hemolytic Anemia0low30
Idiopathic Thrombocytopenic Purpura0low10
Immersion Related Epilepsy0low10
Immune Thrombocytopenia0low10
Immune Thrombocytopenic Purpura0low10
Immunodeficiency 50low50
Immunodeficiency Syndrome, Acquired0low10
Immunodeficiency, X-Linked Progressive Combined Variable0low50
Immunologic Deficiency Syndrome0medium11
Immunologic Deficiency Syndrome, Acquired0low10
Immunologic Deficiency Syndromes0medium11
Immunological Deficiency Syndromes0medium11
Impact Seizure0low10
Impaired Sensation0low10
Inclusion Disease0low10
Infection, Bacterial0medium11
Infection, Mycobacterium avium-intracellulare0low10
Infection, Mycobacterium intracellulare0low10
Infections, Bacterial0medium11
Infections, Cytomegalovirus0low10
Infections, E coli0low10
Infections, Escherichia coli0low10
Infections, Klebsiella0low10
Infections, Paramyxoviridae0low10
Infections, Plasmodium0low10
Inflammation0low40
Injuries0low10
Injuries and Wounds0low10
Injuries, Acute Brain0low30
Injuries, Brain0low30
Injuries, Spinal Cord0low10
Injuries, Wounds0low10
Injury, Ischemia-Reperfusion0low30
Injury, Myocardial Reperfusion0low40
Injury, Reperfusion0low30
Innate Inflammatory Response0low40
Insulin Resistance Syndrome X0low20
Intracranial Astrocytoma0low40
Intracranial Neoplasms0low20
Invasiveness, Neoplasm0low10
Ischemia0low20
Ischemia-Anoxia, Brain0low20
Ischemia-Anoxia, Cerebral0low20
Ischemia-Hypoxia, Brain0low20
Ischemia-Hypoxia, Cerebral0low20
Ischemia-Reperfusion Injury0low30
Ischemia, Cerebral0low40
Ischemia, Myocardial0low10
Ischemic Attack, Transient0low10
Ischemic Encephalopathy0low40
Ischemic Heart Disease0low10
Ischemic-Hypoxic Encephalopathy0low20
Itching0low10
Jacksonian Seizure0low200
Juvenile Pilocytic Astrocytoma0low40
Kahler Disease0low70
Kaposi Sarcoma0low10
Kaposi's Sarcoma0low10
Kidney Cancer0low10
Kidney Neoplasms0low10
Kidney Scarring0low20
Klebsiella Infections0low10
Langerhans Cell Granulomatosis0medium21
Langerhans Cell Granulomatosis, Pulmonary0medium21
Langerhans Cell Histiocytosis0medium21
Langerhans-Cell Granulomatosis0medium21
Langerhans-Cell Histiocytosis0medium21
Large Lymphoid Lymphoma, Nodular0medium21
Large-Cell Lymphoma, Follicular0medium21
Late Onset Alzheimer Disease0low10
Late Post-Traumatic Seizures0low10
Left Ventricle Remodeling0low10
Left Ventricular Hypertrophy0low10
Left Ventricular Remodeling0low10
Left-Sided Heart Failure0low10
Letterer-Siwe Disease0medium21
Leucocythaemia0low70
Leucocythemia0low70
Leukemia0low70
Leukemia L 12100low20
Leukemia L12100low20
Leukemia L51780low10
Leukemia P3880low10
Leukemia, Acute Lymphoblastic0medium32
Leukemia, Acute Myelogenous0medium21
Leukemia, Acute Myeloid0medium21
Leukemia, B Cell, Chronic0medium214
Leukemia, B-Cell0low10
Leukemia, B-Cell, Chronic0medium214
Leukemia, Chronic Lymphatic0medium214
Leukemia, Chronic Lymphocytic0medium214
Leukemia, Chronic Lymphocytic, B-Cell0medium214
Leukemia, Chronic Myelogenous0low10
Leukemia, Chronic Myeloid0low10
Leukemia, Granulocytic0medium52
Leukemia, Granulocytic, Chronic0low10
Leukemia, Hairy Cell0medium353
Leukemia, Lymphoblastic0medium32
Leukemia, Lymphoblastic, Acute0medium32
Leukemia, Lymphoblastic, Acute, L10medium32
Leukemia, Lymphoblastic, Acute, L20medium32
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive0medium32
Leukemia, Lymphoblastic, Chronic0medium214
Leukemia, Lymphocytic0low10
Leukemia, Lymphocytic, Acute0medium32
Leukemia, Lymphocytic, Acute, L10medium32
Leukemia, Lymphocytic, Acute, L20medium32
Leukemia, Lymphocytic, B Cell0low10
Leukemia, Lymphocytic, B-Cell0low10
Leukemia, Lymphocytic, Chronic0medium214
Leukemia, Lymphocytic, Chronic, B Cell0medium214
Leukemia, Lymphocytic, Chronic, B-Cell0medium214
Leukemia, Lymphocytic, Chronic, T Cell0low10
Leukemia, Lymphocytic, Chronic, T-Cell0low10
Leukemia, Lymphocytic, T Cell0low20
Leukemia, Lymphocytic, T-Cell0low20
Leukemia, Lymphoid0low10
Leukemia, Lymphoid, Acute0medium32
Leukemia, Mast-Cell0low10
Leukemia, Monocytic, Chronic0medium52
Leukemia, Myeloblastic, Acute0medium21
Leukemia, Myelocytic0medium52
Leukemia, Myelocytic, Acute0medium21
Leukemia, Myelocytic, Chronic0low10
Leukemia, Myelogenous0medium52
Leukemia, Myelogenous, Acute0medium21
Leukemia, Myelogenous, Chronic0low10
Leukemia, Myelogenous, Chronic, BCR-ABL Positive0low10
Leukemia, Myelogenous, Ph1 Positive0low10
Leukemia, Myelogenous, Ph1-Positive0low10
Leukemia, Myeloid0medium52
Leukemia, Myeloid, Acute0medium21
Leukemia, Myeloid, Acute, M10medium21
Leukemia, Myeloid, Acute, M20medium21
Leukemia, Myeloid, Chronic0low10
Leukemia, Myeloid, Ph1 Positive0low10
Leukemia, Myeloid, Ph1-Positive0low10
Leukemia, Myeloid, Philadelphia Positive0low10
Leukemia, Myeloid, Philadelphia-Positive0low10
Leukemia, Nonlymphoblastic, Acute0medium21
Leukemia, Nonlymphocytic, Acute0medium21
Leukemia, Prolymphocytic0low10
Leukemia, Prolymphocytic, T-Cell0low10
Leukemia, T Cell, Chronic0low10
Leukemia, T-Cell0low20
Leukemia, T-Cell, Chronic0low10
Leukemic Reticuloendotheliosis0medium353
Leukocytopenia0low20
Leukopenia0low20
Liver Cancer0low30
Liver Cancer, Adult0low20
Liver Cell Carcinoma0low20
Liver Cell Carcinoma, Adult0low20
Liver Neoplasms0low30
Liver Neoplasms, Experimental0low40
Liver Steatosis0low10
Lobar Pneumonia0low10
Local Neoplasm Recurrence0low20
Local Neoplasm Recurrences0low20
Locoregional Neoplasm Recurrence0low20
Lou Gehrig Disease0low10
Lou Gehrig's Disease0low10
Lou-Gehrigs Disease0low10
Low Blood Pressure0low30
Lower Motor Neuron Facial Palsy0low10
Lung Adenocarcinoma0low10
Lung Cancer0low100
Lung Diseases0low10
Lung Inflammation0low10
Lung Injuries0low10
Lung Injury0low10
Lung Neoplasms0low100
Lymphatic Diseases0low10
Lymphatic Sarcoma0medium73
Lymphatism0low10
Lymphoblastic Leukemia0medium32
Lymphoblastic Leukemia, Acute0medium32
Lymphoblastic Leukemia, Acute, Adult0medium32
Lymphoblastic Leukemia, Acute, Childhood0medium32
Lymphoblastic Leukemia, Acute, L10medium32
Lymphoblastic Leukemia, Acute, L20medium32
Lymphoblastic Leukemia, Chronic0medium214
Lymphoblastic Lymphoma0medium32
Lymphocytic Leukemia0low10
Lymphocytic Leukemia, Acute0medium32
Lymphocytic Leukemia, B-Cell0low10
Lymphocytic Leukemia, Chronic0medium214
Lymphocytic Leukemia, Chronic, B Cell0medium214
Lymphocytic Leukemia, Chronic, B-Cell0medium214
Lymphocytic Leukemia, L10medium32
Lymphocytic Leukemia, L20medium32
Lymphocytic Leukemia, T Cell, Chronic0low10
Lymphocytic Leukemia, T-Cell0low20
Lymphocytic Leukemia, T-Cell, Chronic0low10
Lymphocytic Lymphoma0medium214
Lymphocytic Lymphoma, Diffuse, Poorly Differentiated0low30
Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated0low30
Lymphocytic Lymphoma, Diffuse, Well Differentiated0medium214
Lymphocytic Lymphoma, Diffuse, Well-Differentiated0medium214
Lymphocytic Lymphoma, Nodular, Poorly Differentiated0medium21
Lymphocytic Lymphoma, Nodular, Poorly-Differentiated0medium21
Lymphocytic Lymphoma, Well Differentiated0medium214
Lymphocytic Lymphoma, Well-Differentiated0medium214
Lymphoid Leukemia0low10
Lymphoma0low90
Lymphoma L51780low10
Lymphoma of Mucosa-Associated Lymphoid Tissue0low10
Lymphoma, Atypical Diffuse Small Lymphoid0medium73
Lymphoma, B-Cell, Marginal Zone0low10
Lymphoma, Centrocytic Small-Cell0low30
Lymphoma, Diffuse0medium73
Lymphoma, Diffuse, Mixed Lymphocytic-Histiocytic0medium73
Lymphoma, Follicular0medium21
Lymphoma, Follicular Large-Cell0medium21
Lymphoma, Follicular, Grade 10medium21
Lymphoma, Follicular, Grade 20medium21
Lymphoma, Follicular, Grade 30medium21
Lymphoma, Follicular, Mixed Cell0medium21
Lymphoma, Follicular, Mixed Lymphocytic-Histiocytic0medium21
Lymphoma, Follicular, Mixed Small and Large Lymphoid0medium21
Lymphoma, Follicular, Small and Large Cleaved Cell0medium21
Lymphoma, Follicular, Small and Large Cleaved-Cell0medium21
Lymphoma, Giant Follicular0medium21
Lymphoma, High-Grade0medium73
Lymphoma, Histiocytic, Nodular0medium21
Lymphoma, Intermediate-Grade0medium73
Lymphoma, Large Cell, Follicular0medium21
Lymphoma, Large Lymphoid, Nodular0medium21
Lymphoma, Large-Cell, Follicular0medium21
Lymphoma, Low-Grade0medium73
Lymphoma, Lymphoblastic0medium32
Lymphoma, Lymphocytic0medium214
Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated0low30
Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated0low30
Lymphoma, Lymphocytic, Diffuse, Well Differentiated0medium214
Lymphoma, Lymphocytic, Diffuse, Well-Differentiated0medium214
Lymphoma, Lymphocytic, Intermediate0low30
Lymphoma, Lymphocytic, Nodular, Poorly Differentiated0medium21
Lymphoma, Lymphocytic, Nodular, Poorly-Differentiated0medium21
Lymphoma, Lymphocytic, Plasmacytoid0low10
Lymphoma, Lymphocytic, Well Differentiated0medium214
Lymphoma, Lymphocytic, Well-Differentiated0medium214
Lymphoma, Lymphoplasmacytoid0low10
Lymphoma, Lymphoplasmacytoid, CLL0medium214
Lymphoma, Malignant0low90
Lymphoma, Mantle-Cell0low30
Lymphoma, Mixed0medium73
Lymphoma, Mixed Cell, Diffuse0medium73
Lymphoma, Mixed Lymphocytic-Histiocytic0medium73
Lymphoma, Mixed Small and Large Cell, Diffuse0medium73
Lymphoma, Mixed-Cell0medium73
Lymphoma, Mixed-Cell, Diffuse0medium73
Lymphoma, Mixed-Cell, Follicular0medium21
Lymphoma, Mucosa-Associated Lymphoid Tissue0low10
Lymphoma, Nodular0medium21
Lymphoma, Nodular, Large Follicular Center Cell0medium21
Lymphoma, Nodular, Large Follicular Center-Cell0medium21
Lymphoma, Nodular, Mixed Lymphocytic Histiocytic0medium21
Lymphoma, Nodular, Mixed Lymphocytic-Histiocytic0medium21
Lymphoma, Nodular, Mixed Small and Large Cell0medium21
Lymphoma, Non-Hodgkin0medium73
Lymphoma, Non-Hodgkin, Familial0medium73
Lymphoma, Non-Hodgkin's0medium73
Lymphoma, Non-Hodgkins0medium73
Lymphoma, Nonhodgkin's0medium73
Lymphoma, Nonhodgkins0medium73
Lymphoma, Pleomorphic0medium73
Lymphoma, Small and Large Cleaved-Cell, Diffuse0medium73
Lymphoma, Small Cleaved Cell, Diffuse0medium73
Lymphoma, Small Cleaved Cell, Follicular0medium21
Lymphoma, Small Cleaved-Cell, Diffuse0medium73
Lymphoma, Small Cleaved-Cell, Follicular0medium21
Lymphoma, Small Follicular Center-Cell0medium21
Lymphoma, Small Lymphocytic0medium214
Lymphoma, Small Lymphocytic, Plasmacytoid0medium214
Lymphoma, Small Lymphoid, Follicular0medium21
Lymphoma, Small Non-Cleaved-Cell0medium73
Lymphoma, Small Noncleaved-Cell0medium73
Lymphoma, Small-Cell0medium214
Lymphoma, Small-Cell, Centrocytic0low30
Lymphoma, T Cell, Cutaneous0low20
Lymphoma, T-Cell0low10
Lymphoma, T-Cell, Cutaneous0low20
Lymphoma, Undifferentiated0medium73
Lymphoma, Undifferentiated, Diffuse0medium73
Lymphoplasmacytoid Lymphoma, CLL0medium214
Lymphoproliferative Disease, X-Linked0low50
Lymphoproliferative Disorders0low50
Lymphoproliferative Syndrome, X-Linked, 10low50
Lymphosarcoma0medium73
Macroglobulinemia0low10
Major Motor Seizure, Alcohol Withdrawal-Induced0low10
Malaria0low10
Malignancies, Hematologic0low10
Malignancy0low40
Malignancy, Hematologic0low10
Malignant Glioma0low30
Malignant Melanoma0low10
Malignant Neoplasm of Breast0low40
Malignant Neoplasms0low40
Malignant Neoplasms, Brain0low20
Malignant Primary Brain Neoplasms0low20
Malignant Primary Brain Tumors0low20
Malignant Tumor of Breast0low40
Malignant Tumor of Urinary Bladder0low10
MALT Lymphoma0low10
Mammary Cancer0low40
Mammary Carcinoma, Human0low40
Mammary Dysplasia0low10
Mammary Neoplasm, Human0low40
Mammary Neoplasms, Experimental0low10
Mammary Neoplasms, Human0low40
Mantle-Cell Lymphoma0low30
Mantle-Zone Lymphoma0low30
Marginal Ulcer0low10
Marginal Zone B-Cell Lymphoma0low10
Marsh Fever0low10
Mast-Cell Leukemia0low10
Mast-Cell Sarcoma0low10
Mastocytoma, Malignant0low10
Melancholia0low10
Melanoma0low10
Melanoma, B160low20
Melanoma, Cloudman S910low20
Melanoma, Experimental0low20
Melanoma, Harding-Passey0low20
Melanomas, Experimental0low20
Mesenteric Vascular Occlusion0low10
Metabolic Cardiovascular Syndrome0low20
Metabolic Syndrome0low20
Metabolic Syndrome X0low20
Metabolic X Syndrome0low20
Metachronous Neoplasms0medium41
Metachronous Second Primary Neoplasms0medium41
Metastase0low20
Metastases, Neoplasm0low20
Metastasis0low20
Metastasis, Neoplasm0low20
Microcalcification0low20
Microcalcinosis0low20
Microglandular Adenosis0low10
Mild Traumatic Brain Injury0low10
Minimal Disease, Residual0low10
Minimal Residual Disease0low10
Mixed Glioma0low30
Mixed Small and Large Cell Lymphoma, Diffuse0medium73
Mixed-Cell Lymphoma0medium73
Mixed-Cell Lymphoma, Diffuse0medium73
Mixed-Cell Lymphoma, Follicular0medium21
Moniliasis0low20
Monocytic Leukemia, Chronic0medium52
Monosomy, Partial0low10
Morphine Abuse0low10
Morphine Addiction0low10
Morphine Dependence0low10
Motor Neuron Disease, Amyotrophic Lateral Sclerosis0low10
Mucosa-Associated Lymphoid Tissue Lymphoma0low10
Mucoviscidosis0low30
Multiple Idiopathic Pigmented Hemangiosarcoma0low10
Multiple Myeloma0low70
Multiple Primary Neoplasms0low10
Multiple Primary Neoplasms, Synchronous0low10
Muscle Contraction0low310
Muscle Relaxation0low100
Muscle Spasticity0low10
Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis0low10
Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis0low10
Musicogenic Epilepsy0low10
MuSK MG0low10
MuSK Myasthenia Gravis0low10
Myasthenia Gravis0low10
Myasthenia Gravis, Generalized0low10
Myasthenia Gravis, Ocular0low10
Mycobacterium avium intracellulare Infection0low10
Mycobacterium avium-intracellulare Infection0low10
Mycobacterium intracellulare Infection0low10
Myeloblastic Leukemia, Acute0medium21
Myelocytic Leukemia0medium52
Myelocytic Leukemia, Acute0medium21
Myelocytic Leukemia, Chronic0low10
Myelodysplastic Syndromes0low10
Myelogenous Leukemia0medium52
Myelogenous Leukemia, Acute0medium21
Myelogenous Leukemia, Chronic0low10
Myelogenous Leukemia, Ph1-Positive0low10
Myeloid Leukemia0medium52
Myeloid Leukemia, Acute0medium21
Myeloid Leukemia, Acute, M10medium21
Myeloid Leukemia, Acute, M20medium21
Myeloid Leukemia, Chronic0low10
Myeloid Leukemia, Ph1-Positive0low10
Myeloid Leukemia, Philadelphia-Positive0low10
Myeloma-Multiple0low70
Myeloma, Multiple0low70
Myeloma, Plasma-Cell0low70
Myelomatosis0low70
Myelopathy, Compressive0low10
Myelopathy, Traumatic0low10
Myocardial Failure0low10
Myocardial Infarct0low50
Myocardial Infarction0low50
Myocardial Ischemia0low10
Myocardial Ischemic Reperfusion Injury0low40
Myocardial Remodeling, Ventricular0low10
Myocardial Reperfusion Injury0low40
Myoclonic Seizure0low200
Myoclonic Seizures0low200
Nagana0low10
Neck Cancer0low10
Neck Neoplasm0low10
Neck Neoplasms0low10
Neoplasia0low40
Neoplasm0low40
Neoplasm Circulating Cells0low10
Neoplasm Invasion0low10
Neoplasm Invasiveness0low10
Neoplasm Metastases0low20
Neoplasm Metastasis0low20
Neoplasm Recurrence, Local0low20
Neoplasm Recurrence, Locoregional0low20
Neoplasm Recurrences, Local0low20
Neoplasm, Residual0low10
Neoplasms0low40
Neoplasms, Adrenal Gland0low90
Neoplasms, Benign0low40
Neoplasms, Bladder0low10
Neoplasms, Bone0low10
Neoplasms, Brain0low20
Neoplasms, Brain, Benign0low20
Neoplasms, Brain, Malignant0low20
Neoplasms, Brain, Primary0low20
Neoplasms, Breast0low40
Neoplasms, Cervical0low10
Neoplasms, Cervix0low10
Neoplasms, Colonic0low30
Neoplasms, Experimental0low10
Neoplasms, Experimental Liver0low40
Neoplasms, Experimental Mammary0low10
Neoplasms, Gastric0low20
Neoplasms, Head0low10
Neoplasms, Head and Neck0low10
Neoplasms, Hematologic0low10
Neoplasms, Hematopoietic0low10
Neoplasms, Hepatic0low30
Neoplasms, Intracranial0low20
Neoplasms, Kidney0low10
Neoplasms, Liver0low30
Neoplasms, Lung0low100
Neoplasms, Metachronous0medium41
Neoplasms, Metachronous Second Primary0medium41
Neoplasms, Multiple Primary0low10
Neoplasms, Neck0low10
Neoplasms, Ovarian0low10
Neoplasms, Pancreatic0low10
Neoplasms, Prostate0low40
Neoplasms, Prostatic0low40
Neoplasms, Pulmonary0low100
Neoplasms, Second Primary0medium41
Neoplasms, Skin0low10
Neoplasms, Splenic0low30
Neoplasms, Stomach0low20
Neoplasms, Synchronous0low10
Neoplasms, Synchronous Multiple Primary0low10
Neoplasms, Therapy-Associated0medium41
Neoplasms, Therapy-Related0medium41
Neoplasms, Thyroid0low20
Neoplasms, Treatment-Associated0medium41
Neoplasms, Treatment-Related0medium41
Neoplasms, Upper Aerodigestive Tract0low10
Neoplastic Cell Transformation0low10
Neoplastic Cells, Circulating0low10
Neoplastic Transformation, Cell0low10
Nephroid Carcinoma0low10
Nervous System Paraneoplastic Syndromes0low10
Neuroblastoma0low70
Neuromuscular Blockade0low10
Neurosis, Depressive0low10
Neutropenia0medium21
Nodular Large Follicular Center-Cell Lymphoma0medium21
Non-Convulsive Status Epilepticus0low20
Non-Epileptic Seizure0low200
Non-Epileptic Seizures0low200
Non-Hodgkin Lymphoma0medium73
Non-Hodgkin's Lymphoma0medium73
Non-Lipid Reticuloendotheliosis0medium21
Non-Small Cell Lung Cancer0low10
Non-Small Cell Lung Carcinoma0low10
Non-Small-Cell Lung Carcinoma0low10
Nonepileptic Seizure0low200
Nonepileptic Seizures0low200
Nonlymphoblastic Leukemia, Acute0medium21
Nonlymphocytic Leukemia, Acute0medium21
Nonsmall Cell Lung Cancer0low10
Numbness0low10
Oligoastrocytoma, Mixed0low40
Opportunistic Infections0low10
Osteoclastic Bone Loss0low40
Osteogenic Sarcoma0low10
Osteosarcoma0low10
Osteosarcoma Tumor0low10
Ovarian Cancer0low10
Ovarian Neoplasms0low10
Ovary Cancer0low10
Ovary Neoplasms0low10
Oxygen Deficiency0low50
P388D(1) Leukemia0low10
Pain0low10
Pain, Burning0low10
Pain, Crushing0low10
Pain, Migratory0low10
Pain, Radiating0low10
Pain, Splitting0low10
Paludism0low10
Pancreas Cancer0low10
Pancreas Neoplasms0low10
Pancreatic Cancer0low10
Pancreatic Cystic Fibrosis0low30
Pancreatic Neoplasms0low10
Pancreatic Parenchyma with Edema0low10
Pancreatic Parenchymal Edema0low10
Pancreatitis0low10
Pancreatitis, Acute0low10
Pancreatitis, Acute Edematous0low10
Papillary Renal Cell Carcinoma0low10
Parainfluenza0low10
Parainfluenza Virus Infections0low10
Paramyxoviridae Infections0low10
Paraneoplastic Autonomic Dysfunction0low10
Paraneoplastic Encephalomyelitis0low10
Paraneoplastic Neurologic Syndromes0low10
Paraneoplastic Syndromes, Nervous System0low10
Parenterally-Transmitted Non-A, Non-B Hepatitis0low10
Partial Complex Epilepsy, Cryptogenic0low10
Partial Complex Epilepsy, Symptomatic0low10
Partial Monosomy0low10
Partial Seizure0low200
Partial Seizures0low200
Pathologic Calcification0low20
Pediatric Respiratory Distress Syndrome0low10
Peliosis Hepatis0low10
Peptic Ulcer0low10
Pericementitis0low10
Periodontitis0low10
Peripancreatic Fat Necrosis0low10
Petit Mal Convulsion0low200
Petit Mal Status0low20
Pheochromocytoma0low110
Pheochromocytoma, Extra-Adrenal0low110
Photosensitive Epilepsy0low10
Pilocytic Astrocytoma0low40
Plasma Cell Myeloma0low70
Plasmodium Infections0low10
Pneumonia0low10
Pneumonia, Bacterial0low10
Pneumonia, Lobar0low10
Pneumonitis0low10
Poisoning0low10
Poisoning, Blood0low10
Polyopsia0low10
Post-Transfusion Purpura0low10
Post-Traumatic Myelopathy0low10
Post-Traumatic Seizure Disorder0low10
Posterior Circulation Transient Ischemic Attack0low10
Postprandial Hyperglycemia0low10
Posttransfusion Purpura0low10
Precursor Cell Lymphoblastic Leukemia-Lymphoma0medium32
Pregnancy0low40
Presenile Alzheimer Dementia0low10
Primary Brain Neoplasms0low20
Primary Macroglobulinemia0low10
Primary Malignant Brain Neoplasms0low20
Primary Malignant Brain Tumors0low20
Primary Senile Degenerative Dementia0low10
Prolymphocytic Leukemia0low10
Prostate Cancer0low40
Prostate Neoplasms0low40
Prostatic Cancer0low40
Prostatic Neoplasms0low40
Proteinuria0low10
Pruritis0low10
Pruritus0low10
PT-NANBH0low10
Pulmonary Cancer0low100
Pulmonary Cystic Fibrosis0low30
Pulmonary Disease0low10
Pulmonary Disease, Chronic Obstructive0low10
Pulmonary Diseases0low10
Pulmonary Histiocytosis X0medium21
Pulmonary Inflammation0low10
Pulmonary Injury0low10
Pulmonary Langerhans Cell Granulomatosis0medium21
Pulmonary Neoplasms0low100
Pure Red-Cell Aplasia0low10
Purpura, Thrombocytopenic, Autoimmune0low10
Purpura, Thrombocytopenic, Idiopathic0low10
Purtilo Syndrome0low50
Pyaemia0low10
Pyemia0low10
Pyohemia0low10
Reading Epilepsy0low10
Reaven Syndrome X0low20
Recrudescence0medium51
Recurrence0medium51
Recurrence, Local Neoplasm0low20
Recurrence, Locoregional Neoplasm0low20
Recurrences, Local Neoplasm0low20
Red-Cell Aplasia, Pure0low10
Reduced Sensation0low10
Reflex Epilepsy0low10
Reflex Epilepsy, Audiogenic0low10
Reflex Epilepsy, Cursive (Running)0low10
Reflex Epilepsy, Eating-Induced0low10
Reflex Epilepsy, Musicogenic0low10
Reflex Epilepsy, Photosensitive0low10
Reflex Epilepsy, Reading0low10
Reflex Epilepsy, Visual Pattern0low10
Relapse0medium51
Remittent Fever0low10
Renal Cancer0low10
Renal Carcinoma0low10
Renal Cell Cancer0low10
Renal Cell Carcinoma0low10
Renal Cell Carcinoma, Papillary0low10
Renal Collecting Duct Carcinoma0low10
Renal Neoplasms0low10
Reperfusion Damage0low30
Reperfusion Injury0low30
Reperfusion Injury, Myocardial0low40
Research-Related Injuries0low10
Residual Cancer0low10
Residual Disease, Minimal0low10
Residual Neoplasm0low10
Residual Tumor0low10
Residual Tumour0low10
Respiratory Distress Syndrome0low10
Respiratory Distress Syndrome, Acute0low10
Respiratory Distress Syndrome, Adult0low10
Respiratory Distress Syndrome, Pediatric0low10
Reticuloendotheliosis, Leukemic0medium353
Reticulolymphosarcoma0low90
Reticulosarcoma0medium73
Reticulum Cell Sarcoma0medium73
Reticulum-Cell Sarcoma0medium73
Rheumatoid Arthritis0low10
Right-Sided Heart Failure0low10
Rigidity, Decerebrate0low10
Rigidity, Decorticate0low10
Rosai-Dorfman Disease0low10
Salivary Gland Virus Disease0low10
Sarcoma, Germinoblastic0low90
Sarcoma, Kaposi0low10
Sarcoma, Lymphatic0medium73
Sarcoma, Mast-Cell0low10
Sarcoma, Osteogenic0low10
Sarcoma, Reticulum-Cell0medium73
Sarcomatoid Renal Cell Carcinoma0low10
Schueller-Christian Disease0medium21
Second Cancer0medium41
Second Malignancy0medium41
Second Neoplasm0medium41
Second Primary Neoplasms0medium41
Second Primary Neoplasms, Metachronous0medium41
Seizure0low200
Seizure Disorder0low70
Seizure Disorder, Complex Partial0low10
Seizure Disorder, Post-Traumatic0low10
Seizures0low200
Seizures, Alcoholic0low10
Seizures, Auditory0low200
Seizures, Clonic0low200
Seizures, Convulsive0low200
Seizures, Epileptic0low200
Seizures, Focal0low200
Seizures, Generalized0low200
Seizures, Gustatory0low200
Seizures, Motor0low200
Seizures, Olfactory0low200
Seizures, Sensory0low200
Seizures, Somatosensory0low200
Seizures, Tonic0low200
Seizures, Tonic-Clonic0low200
Seizures, Vertiginous0low200
Seizures, Vestibular0low200
Seizures, Visual0low200
Senile Dementia, Acute Confusional0low10
Senile Dementia, Alzheimer Type0low10
Sensitivity and Specificity0low60
Sensitivity, Contact0low10
Sepsis0low10
Septicemia0low10
Severe Sepsis0low10
Shock Lung0low10
Simple Partial Status Epilepticus0low20
Single Seizure0low200
Sinus Histiocytosis with Massive Lymphadenopathy0low10
Skin Cancer0low10
Skin Neoplasms0low10
Small Airway Remodeling0low10
Small Airway Remodelling0low10
Small Cleaved-Cell Lymphoma, Diffuse0medium73
Small Cleaved-Cell Lymphoma, Follicular0medium21
Small Follicular Center-Cell Lymphoma0medium21
Small Non-Cleaved-Cell Lymphoma0medium73
Small Noncleaved-Cell Lymphoma0medium73
Small-Cell Lymphoma0medium214
Spastic0low10
Spinal Cord Compression0low10
Spinal Cord Compression, Extramedullary0low10
Spinal Cord Contusion0low10
Spinal Cord Injuries0low10
Spinal Cord Laceration0low10
Spinal Cord Transection0low10
Spinal Cord Trauma0low10
Spleen Cancer0low30
Spleen Neoplasms0low30
Splenic Cancer0low30
Splenic Neoplasms0low30
Splenomegaly0medium21
Squamous Cell Carcinoma0low10
Status Epilepticus0low20
Status Epilepticus, Alcohol Withdrawal-Induced0low10
Status Epilepticus, Complex Partial0low20
Status Epilepticus, Electrographic0low20
Status Epilepticus, Generalized0low20
Status Epilepticus, Generalized Convulsive0low20
Status Epilepticus, Grand Mal0low20
Status Epilepticus, Non-Convulsive0low20
Status Epilepticus, Simple Partial0low20
Status Epilepticus, Subclinical0low20
Status Lymphaticus0low10
Steatohepatitis0low10
Steatosis of Liver0low10
Stomach Cancer0low20
Stomach Neoplasms0low20
Stomach Ulcer0low10
Streptozocin Diabetes0low30
Streptozotocin Diabetes0low30
Stroke0low10
Stroke, Acute0low10
Subependymal Giant Cell Astrocytoma0low40
Substance Withdrawal Syndrome0low20
Sudden Cardiac Arrest0low10
Sudden Cardiac Death0low10
Suffering, Physical0low10
Susceptibility, Disease0low10
Symptom Cluster0low10
Symptomatic Partial Complex Epilepsy0low10
Synchronous Multiple Primary Neoplasms0low10
Synchronous Neoplasms0low10
Syndrome0low10
Syndrome X, Insulin Resistance0low20
Syndrome X, Metabolic0low20
Systemic Aleukemic Reticuloendotheliosis0medium21
T Lymphocytic Leukemia0low20
T-Cell Leukemia0low20
T-Cell Leukemia, Chronic0low10
T-Cell Lymphoma0low10
T-Cell Lymphoma, Cutaneous0low20
T-Cell Prolymphocytic Leukemia0low10
T-Lymphocytic Leukemia0low20
T-Lymphocytic Leukemia, Chronic0low10
Tactile Reflex Epilepsy0low10
TAGHD0low10
Tetraploid0low10
Tetraploidy0low10
Therapy-Associated Cancer0medium41
Therapy-Associated Neoplasms0medium41
Therapy-Related Cancer0medium41
Therapy-Related Neoplasms0medium41
Thrombocytopenia0low10
Thrombocytopenic Purpura, Autoimmune0low10
Thrombopenia0low10
Thrombosis0low30
Thrombus0low30
Thyroid Adenoma0low20
Thyroid Cancer0low20
Thyroid Carcinoma0low20
Thyroid Neoplasms0low20
TIA (Transient Ischemic Attack)0low10
Tonic Clonic Seizure0low200
Tonic Seizure0low200
Tonic Seizures0low200
Tonic-Clonic Seizure0low200
Tonic-Clonic Seizures0low200
Transformation, Neoplastic Cell0low10
Transformation, Viral Cell0low20
Transfusion Reaction0low10
Transfusion-Associated Allergic Reaction0low10
Transfusion-Associated Circulatory Overload0low10
Transfusion-Associated Dyspnea0low10
Transfusion-Associated Graft Vs. Host Disease0low10
Transfusion-Transmitted Infection0low10
Transient Ischemic Attack0low10
Transient Ischemic Attack, Anterior Circulation0low10
Transient Ischemic Attack, Brain Stem0low10
Transient Ischemic Attack, Brainstem0low10
Transient Ischemic Attack, Carotid Circulation0low10
Transient Ischemic Attack, Posterior Circulation0low10
Transient Ischemic Attack, Vertebrobasilar Circulation0low10
Transient Ischemic Attacks, Crescendo0low10
Trauma0low10
Treatment-Associated Cancer0medium41
Treatment-Associated Neoplasms0medium41
Treatment-Related Cancer0medium41
Treatment-Related Neoplasms0medium41
Tropical Eosinophilia0low10
Trypanosomiasis, African0low10
Tumor Cells, Embolic0low10
Tumor Lysis Syndrome0low10
Tumorigenic Transformation0low10
Tumors0low40
Tumors, Breast0low40
Tumour Lysis Syndrome0low10
Type 2 Histiocytosis0medium21
UADT Neoplasm0low10
UADT Neoplasms0low10
Undifferentiated Lymphoma0medium73
Unipolar Depression0low10
Upper Aerodigestive Tract Neoplasm0low10
Upper Aerodigestive Tract Neoplasms0low10
Upper Motor Neuron Facial Palsy0low10
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Uterine Cervical Cancer0low10
Uterine Cervical Neoplasms0low10
Vascular Accident, Brain0low10
Vascular Hypotension0low30
Ventricle Remodeling0low10
Ventricular Hypertrophy, Left0low10
Ventricular Remodeling0low10
Vertebral Ankylosing Hyperostosis0low10
Vertebrobasilar Circulation Transient Ischemic Attack0low10
Viral Cell Transformation0low20
Visceral Steatosis0low10
Visual Pattern Reflex Epilepsy0low10
Waldenstrom Macroglobulinemia0low10
Waldenstrom's Macroglobulinaemia0low10
Waldenstrom's Macroglobulinemia0low10
Werlhof Disease0low10
Werlhof's Disease0low10
Withdrawal Symptoms0low20
Wounds0low10
Wounds and Injuries0low10
Wounds and Injury0low10
Wounds, Injury0low10
Writing-Induced Reflex Epilepsy0low10
X-Linked Lymphoproliferative Disease0low50
X-Linked Lymphoproliferative Disorder0low50
X-Linked Lymphoproliferative Syndrome0low50
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (14)

ArticleYear
Mechanism of 2-chloroadenosine toxicity to PC3 cell line.
The Prostate, Sep-15, Volume: 66, Issue: 13		2006
8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblastic leukemia cells to TNFalpha-induced apoptosis is via inactivation of NF-kappaB.
Leukemia research, Volume: 25, Issue: 5		2001
8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine.
Blood, Oct-15, Volume: 92, Issue: 8		1998
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Brain research, Jul-11, Volume: 762, Issue: 1-2		1997
Relationship between phosphorylation and cytotoxicity of 2-chloroadenosine and 6-methylmercaptopurine riboside in human cells.
Biochimica et biophysica acta, Apr-10, Volume: 798, Issue: 2		1984
2-Chloroadenosine prevents kainic acid-induced toxicity in rat striatum.
Neuroscience letters, Nov-11, Volume: 93, Issue: 2-3		1988
2-chloroadenosine attenuates kainic acid-induced toxicity within the rat straitum: relationship to release of glutamate and Ca2+ influx.
British journal of pharmacology, Volume: 98, Issue: 1		1989
Mechanism of action and selective toxicity of ascamycin, a nucleoside antibiotic.
Antimicrobial agents and chemotherapy, Volume: 27, Issue: 2		1985
Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.
Advances in experimental medicine and biology, Volume: 253B		1989
2-Chloroadenosine attenuates NMDA, kainate, and quisqualate toxicity.
Neuroscience letters, May-27, Volume: 126, Issue: 2		1991
Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.
The Journal of clinical investigation, Volume: 86, Issue: 5		1990
Potentiation of cocaine and d-amphetamine toxicity with caffeine.
The American journal of emergency medicine, Volume: 10, Issue: 3		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (8)

ArticleYear
A novel approach to improve the pharmacokinetic properties of 8-chloro-adenosine by the dual combination of lipophilic derivatisation and liposome formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Jan-23, Volume: 48, Issue: 1-2		2013
[Preparation of 8-chloro-adenosine long circulation liposomes and its pharmacokinetics in rats].
Yao xue xue bao = Acta pharmaceutica Sinica, Volume: 40, Issue: 4		2005
Determination of pharmacokinetics of 8-chloroadenosine and its two major metabolites in dogs by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications, Sep-15, Volume: 746, Issue: 2		2000
Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo.
British journal of pharmacology, Volume: 118, Issue: 2		1996
Effects of adenosine receptor agonists on volume-activated ion transport in pig red cells.
Journal of cellular physiology, Volume: 146, Issue: 2		1991
On the pharmacokinetics of 2-chloro-2'-deoxyadenosine in humans.
Cancer research, Oct-15, Volume: 51, Issue: 20		1991
Extracellular 2-chloroadenosine and ATP stimulate volume-sensitive Cl- current and calcium mobilization in human tracheal 9HTEo- cells.
FEBS letters, Jun-08, Volume: 304, Issue: 1		1992
Effects of fluoroquinolone antimicrobials alone and in conjunction with theophylline on seizures in amygdaloid kindled rats. Mechanistic and pharmacokinetic study.
Epilepsy research, Volume: 13, Issue: 1		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (4)

ArticleYear
A novel approach to improve the pharmacokinetic properties of 8-chloro-adenosine by the dual combination of lipophilic derivatisation and liposome formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Jan-23, Volume: 48, Issue: 1-2		2013
[2-CDA in treatment of hairy cell leukemia: a comparison between intravenous and subcutaneous administration. Swiss Study Group of Applied Cancer Research].
Schweizerische medizinische Wochenschrift, Oct-17, Volume: 128, Issue: 42		1998
The role of receptor binding in drug discovery.
Journal of natural products, Volume: 56, Issue: 4		1993
Influence of adenosine receptor blockade on renal function and renal autoregulation.
Journal of the American Society of Nephrology : JASN, Volume: 2, Issue: 5		1991
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (29)

ArticleYear
A novel approach to improve the pharmacokinetic properties of 8-chloro-adenosine by the dual combination of lipophilic derivatisation and liposome formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Jan-23, Volume: 48, Issue: 1-2		2013
Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent.
Bioresource technology, Volume: 118		2012
Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.
Acta physiologica (Oxford, England), Volume: 199, Issue: 2		2010
2-chloroadenosine modulates PAR-1 and IL-23 expression and enhances docetaxel effects on PC3 cells.
The Prostate, Mar-01, Volume: 68, Issue: 4		2008
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
European journal of pharmacology, Oct-12, Volume: 428, Issue: 3		2001
Assessment of 2-chloroadenosine treatment after experimental traumatic brain injury in the rat using arterial spin-labeled MRI: a preliminary report.
Acta neurochirurgica. Supplement, Volume: 76		2000
Assessment of the effect of 2-chloroadenosine in normal rat brain using spin-labeled MRI measurement of perfusion.
Magnetic resonance in medicine, Volume: 45, Issue: 5		2001
Induction of apoptosis by 2-chloro-2'deoxyadenosine (2-CdA) alone and in combination with other cytotoxic drugs: synergistic effects on normal and neoplastic lymphocytes by addition of doxorubicin and mitoxantrone.
Leukemia & lymphoma, Volume: 36, Issue: 5-6		2000
Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience, Oct-15, Volume: 18, Issue: 20		1998
Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices.
British journal of pharmacology, Volume: 117, Issue: 7		1996
Effects of 8-chloro-cyclic adenosine monophosphate on the growth and sensitivity to doxorubicin of multidrug-resistant tumour cell lines.
Pharmacological research, Volume: 30, Issue: 1		1994
Mechanism of potentiation by diazepam of adenosine response.
Life sciences, Jan-02, Volume: 34, Issue: 1		1984
The ionic basis of adenosine receptor actions on post-ganglionic neurones in the rat.
The Journal of physiology, Volume: 336		1983
2-chloroadenosine increases calcium mobilization from mouse calvaria in vitro.
Acta endocrinologica, Volume: 100, Issue: 2		1982
Evidence for an A2/Ra adenosine receptor in the guinea-pig trachea.
British journal of pharmacology, Volume: 76, Issue: 3		1982
Adenosine-elicited accumulation of adenosine 3', 5'-cyclic monophosphate in the chick embryo retina.
Journal of neurochemistry, Volume: 38, Issue: 2		1982
Pharmacological characterization of CGS 15943A: a novel nonxanthine adenosine antagonist.
The Journal of pharmacology and experimental therapeutics, Volume: 242, Issue: 3		1987
Interactions between caffeine and adenosine agonists in producing embryo resorptions and malformations in mice.
Toxicology and applied pharmacology, Volume: 91, Issue: 3		1987
Effects of adenosine and its analogues on porcine basilar arteries: are only A2 receptors involved?
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Volume: 8, Issue: 1		1988
Interactive effects of caffeine, 2-chloroadenosine and haloperidol on activity, social investigation and play fighting of juvenile rats.
Pharmacology, biochemistry, and behavior, Volume: 22, Issue: 3		1985
Adenosine receptor-mediated effects by nonmetabolizable adenosine analogs in preovulatory rat granulosa cells: a putative local regulatory role of adenosine in the ovary.
Endocrinology, Volume: 122, Issue: 1		1988
Microdialysis of intercellular adenosine concentration in subcutaneous tissue in humans.
The American journal of physiology, Volume: 256, Issue: 2 Pt 1		1989
Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices.
Brain research, Jan-16, Volume: 477, Issue: 1-2		1989
The coexistence of adenosine A1 and A2 receptors in guinea-pig aorta.
European journal of pharmacology, Nov-13, Volume: 190, Issue: 3		1990
Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.
International journal of obesity, Volume: 15, Issue: 5		1991
Cold acclimation induces desensitization to adenosine in brown fat cells without changing receptor binding.
The American journal of physiology, Volume: 258, Issue: 5 Pt 1		1990
2-Chlorodeoxyadenosine inhibits the repair of DNA double-strand breaks and does not inhibit the repair of DNA single-strand breaks in X-irradiated Chinese hamster V79 cells.
Chemico-biological interactions, Volume: 79, Issue: 3		1991
Influence of diazepam, alpidem, zolpidem and zopiclone, on the response to adenosine of the guinea pig isolated trachea.
Fundamental & clinical pharmacology, Volume: 5, Issue: 1		1991
A phase I clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume: 9, Issue: 3		1991
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Induction of apoptosis by 2-chloro-2'deoxyadenosine (2-CdA) alone and in combination with other cytotoxic drugs: synergistic effects on normal and neoplastic lymphocytes by addition of doxorubicin and mitoxantrone.
Leukemia & lymphoma, Volume: 36, Issue: 5-6		2000
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]