Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
3-hydroxybenzylhydrazine | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
p-chloromercuribenzoic acid | Leishmania mexicana mexicana | Potency | 3.9811 | 2 | 0 |
5-(n,n-hexamethylene)amiloride | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
ag 127 | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
amlexanox | Leishmania mexicana mexicana | Potency | 7.0795 | 2 | 0 |
anisindione | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | Leishmania mexicana mexicana | Potency | 3.1623 | 2 | 0 |
clotrimazole | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
dephostatin | Leishmania mexicana mexicana | Potency | 3.1623 | 2 | 0 |
disulfiram | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
ebselen | Leishmania mexicana mexicana | Potency | 15.5513 | 5 | 0 |
s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
hydralazine | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 0 |
indirubin-3'-monoxime | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
indoprofen | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
nsc 664704 | Leishmania mexicana mexicana | Potency | 6.3096 | 2 | 0 |
leflunomide | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
mitoxantrone | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
fg 7142 | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
niclosamide | Leishmania mexicana mexicana | Potency | 2.5119 | 2 | 0 |
quinone | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
pd 98059 | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
protoporphyrin ix | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
riluzole | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
sanguinarine | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
sb 206553 | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
thiabendazole | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
triamterene | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
levodopa | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
quinophthalone | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
pseudoephedrine | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
dehydrothio-4-toluidine | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
suramin sodium | Leishmania mexicana mexicana | Potency | 0.7943 | 2 | 0 |
indirubin | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
hematoxylin | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
4-(benzoylamino)-2-hydroxybenzoic acid | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
2-phenylbenzimidazole | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
2,5-diphenyloxazole | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
drometrizole | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
2-(alpha-thenoylamino)-2-nitro-5-thiazole | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
1,6-bismaleimidohexane | Leishmania mexicana mexicana | Potency | 12.8000 | 3 | 0 |
diacerein | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
metergoline | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
n-(cyclohexylthio)phthalimide | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
k 308 | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
methyldopa | Leishmania mexicana mexicana | Potency | 0.7943 | 2 | 0 |
nitazoxanide | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
xanthyletine | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
pifexole | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
2-(2'-pyridyl)benzimidazole | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
methyl fluorone black | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
4-(2-thiazolylazo)resorcinol | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3,5-di-tert-butyl-1,2-benzoquinone | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
witisol | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
beta-carboline-3-carboxylic acid methyl ester | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
1,4-di(2'-thienyl)-1,4-butadione | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
corbadrine | Leishmania mexicana mexicana | Potency | 3.1623 | 2 | 0 |
2-phenyl-1,2-benzisothiazol-3-(2h)-one | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
N-(4-methoxyphenyl)carbamic acid propan-2-yl ester | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
1-Anilino-9,10-dioxo-2-anthroic acid | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
gossypol acetic acid | Leishmania mexicana mexicana | Potency | 0.7943 | 2 | 0 |
2-pyridin-4-yl-1,3-benzothiazole | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2-[(6-butoxy-3-pyridinyl)amino]-4-chlorobenzoic acid | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
2-hydroxyestradiol | Leishmania mexicana mexicana | Potency | 3.4384 | 3 | 0 |
nsc228155 | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
Dubamine | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
4,5,7-trihydroxy-9,10-dioxo-2-anthracenecarboxylic acid | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
(R)-norlaudanosoline | Leishmania mexicana mexicana | Potency | 0.5012 | 2 | 0 |
resveratrol | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
6-bromoindirubin-3'-oxime | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
chalcone | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
7-methoxyisoflavone | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2'-hydroxychalcone | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
gw9662 | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
3-methyl-4-(7-methyl-2-indolizinyl)-1,2,5-oxadiazole | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
N,N-dimethyl-6-phenyl-3-pyridazinamine | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-(3,5-dimethoxyphenyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
acetic acid (11-oxo-6H-benzo[c][1]benzoxepin-2-yl) ester | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
sch-202676 | Leishmania mexicana mexicana | Potency | 5.0119 | 2 | 0 |
4-cyclohexyl-3-(3-pyridinyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
4-cyclohexyl-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 4.4668 | 2 | 0 |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-3-furamide | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-hydroxy-3-pyrazolecarboxylic acid ethyl ester | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
phenylthiazolylthiourea | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
2-[(3-methyl-2-thiophenyl)methylidene]indene-1,3-dione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
2-(thiophen-2-ylmethylidene)indene-1,3-dione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
krm iii | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2-(4-hydroxyanilino)-1,4-naphthoquinone | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
4-[2-(1-methyl-2-benzimidazolyl)ethyl]aniline | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-(2,5-dimethylphenyl)-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
nsc185058 | Leishmania mexicana mexicana | Potency | 13.4270 | 2 | 0 |
2-(4-fluorophenyl)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-[(4-methylphenoxy)methyl]-4-phenyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
1-(4,5-dihydrothiazol-2-yl)-3-phenylurea | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-(2,3-dimethyl-1H-indol-5-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
3-(3-nitrophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
N-(2-fluoro-5-methylphenyl)-3-phenylpropanamide | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
4-[[(4-acetyloxy-3-methoxyphenyl)-oxomethyl]amino]benzoic acid | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
acetic acid [4-[(4-hydroxyanilino)-oxomethyl]-2-methoxyphenyl] ester | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
3-bromo-N-(2-furanylmethyl)benzamide | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
N-(cyclopentylideneamino)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
4-(3-chlorophenyl)-3-methyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
2-methyl-N-(2-naphthalenyl)-3-furancarboxamide | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine) | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
2-(ethylthio)-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
3-(2-furanyl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
N-(1,3-benzodioxol-5-yl)-5-methyl-2-furancarboxamide | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
3-(1,3-dimethyl-4-pyrazolyl)-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
4-(2-methylphenyl)-3-(5-methyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
3-(4-ethyl-5-methyl-3-thiophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-(3-methylphenyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
3-(1,3-benzodioxol-5-yl)-4-(2,5-dimethylphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 3.9811 | 2 | 0 |
3-(1-benzothiophen-3-yl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
4-(3-methylphenyl)-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
3-(4,5-dimethyl-3-thiophenyl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
3-(2-methyl-3-furanyl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenol | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
N-(2-fluorophenyl)-3-phenylpropanamide | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
benzoic acid (2-oxo-2-thiophen-2-ylethyl) ester | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
4-sulfanylidene-1,6,7,8,9,10-hexahydropyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
2-[[anilino(oxo)methyl]amino]-N-(2-furanylmethyl)benzamide | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
4-[methyl(methylsulfonyl)amino]-N-(2-phenylethyl)benzamide | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
4-phenacyloxybenzoic acid methyl ester | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
3-(4-ethoxyphenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamide | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
3-[4-(2-methylphenyl)-5-sulfanylidene-1H-1,2,4-triazol-3-yl]-1H-pyridazin-6-one | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
3-[5-(2-furanyl)-1H-pyrazol-3-yl]-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 3.5481 | 2 | 0 |
4-(4-chlorophenyl)-3-(2-phenylethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
N-(4-methoxyphenyl)-2-(methylthio)benzamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
4-phenyl-3-(thiophen-2-ylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
4-(2-methylphenyl)-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
6-hydroxy-2-(4-nitrophenyl)-3,1-benzoxazin-4-one | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
umi-77 | Leishmania mexicana mexicana | Potency | 3.5481 | 2 | 0 |
N-(5-chloro-2-pyridinyl)-2-ethyl-3-pyrazolecarboxamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
N-(3-methoxyphenyl)-4-(1-oxopropylamino)benzamide | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
3-[[1-oxo-2-[(4,6,9-trimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]ethyl]amino]benzoic acid | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-3-isoxazolecarboxamide | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
N-(1,3-benzodioxol-5-yl)-2-[[4-(4-methylphenyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]acetamide | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
4-(2-chlorophenyl)-3-(5-methyl-3-phenyl-4-isoxazolyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
4-methyl-2-(4-nitrophenyl)-5-thiazolecarboxylic acid | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
3-phenyl-2H-1,4-benzoxazine | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
2-(6-chloro-3-pyridinyl)-1H-benzimidazole | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
cis-resveratrol | Leishmania mexicana mexicana | Potency | 2.5119 | 2 | 0 |
4-butyl-3-(5-ethyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
4-butyl-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
4-butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
1-[[4-[(3,4-dichlorophenyl)thio]-3-pyridinyl]sulfonyl]-3-propylurea | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-(2-bromo-4-methylphenyl)-3-[5-(2-furanyl)-1H-pyrazol-3-yl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
4-(2,5-dimethoxyphenyl)-3-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
3-(1,3-benzodioxol-5-yl)-4-(3-chloro-4-fluorophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
2-[[4-(2-chlorophenyl)-5-sulfanylidene-1H-1,2,4-triazol-3-yl]methyl]-1-phthalazinone | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 3.1623 | 2 | 0 |
3,4,5-trimethoxy-N-[[2-(4-morpholinyl)anilino]-sulfanylidenemethyl]benzamide | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
4-(2,5-dimethoxyphenyl)-3-(3-phenyl-1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
3-(4-bromophenyl)-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
N-[(tert-butylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-phenyl-1,3,4-oxadiazol-2-amine | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
5-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
5-(3,4-dimethoxyphenyl)-3-(4-ethoxyphenyl)-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 2.8184 | 2 | 0 |
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-4-nitrobenzenesulfonamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
2,5-dimethoxybenzenesulfonic acid (1,3-dioxo-2-isoindolyl) ester | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
4-butyl-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
1-(2-chlorophenyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)ethanone | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
2-chloro-3-pyridinecarboxylic acid [2-(4-fluorophenyl)-2-oxoethyl] ester | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-(1,3-benzodioxol-5-yl)-4-phenyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 7.0795 | 2 | 0 |
7-methyl-N-[4-(4-morpholinyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
3-methoxy-N-(4-methyl-2-thiazolyl)benzamide | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
3-[[(2,4-dichlorophenyl)methylthio]methyl]-4-propan-2-yl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
2-[3-(4-pyridyl)-1H-1,2,4-triazol-5-yl]pyridine | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
N-[(2-hydroxyphenyl)-oxomethyl]-2,3-dihydrobenzofuran-5-carboxamide | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
4-(2-furanylmethyl)-3-[(3-methoxyphenyl)methyl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
3-[4-(4-chlorophenyl)-1-piperazinyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
3-(4-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-1-phenyl-1-propanone | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2-(3,4-dimethylphenyl)-5-ethyl-5-phenyl-1,2,4-triazolidine-3-thione | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
4-(1-phenylethyl)-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
4-[1-(4-fluorophenyl)ethyl]-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
6-methyl-2-(phenylethynyl)pyridine | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
3-(benzenesulfonyl)-3-(4-methoxyphenyl)-1-phenyl-1-propanone | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2-quinolinecarboxylic acid (1-oxo-1-phenylpropan-2-yl) ester | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
yl-109 | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
4-[4-[[1-(2-methylbutan-2-yl)-5-tetrazolyl]-(6-quinolinyl)methyl]-1-piperazinyl]phenol | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-[4-[(1-tert-butyl-5-tetrazolyl)-pyridin-4-ylmethyl]-1-piperazinyl]phenol | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
3-(4-bromophenyl)-4-(2-furanylmethyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
4-[[(3-methoxyphenyl)-oxomethyl]amino]benzoic acid | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
4-butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
4-butyl-3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
ro 41-0960 | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
N-cycloheptyl-4-(2-oxolanylmethoxy)benzamide | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
2-[(4-amino-7-tert-butyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)thio]acetic acid | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-nitro-N-(2-phenylethyl)-2-pyridinamine | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
4-(2-methylcyclohexyl)-3-(3-pyridinyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
2-[2-[5-amino-4-(3-thiophenyl)-1-pyrazolyl]-4-phenyl-5-thiazolyl]acetic acid | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
4-[[(2-methyl-5-nitro-1H-imidazol-4-yl)thio]methyl]-2-nitrophenol | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
3,5-bis(4-methoxyphenyl)-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 1.4125 | 2 | 0 |
4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
2-methoxy-N-(5-phenyl-1,2,4-thiadiazol-3-yl)benzamide | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
2-[[2-(3,4-dimethoxyanilino)-2-oxoethyl]thio]-3-pyridinecarboxylic acid propan-2-yl ester | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 39.8107 | 2 | 0 |
2-(2-fluoroanilino)-3-pyridinecarboxylic acid [2-[(1,1-dioxo-3-thiolanyl)-methylamino]-2-oxoethyl] ester | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
4-(4-chlorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 35.4813 | 2 | 0 |
4-(4-chlorophenyl)-3-phenyl-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 2.5119 | 2 | 0 |
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[[2-(2-pyridinyl)-1-benzimidazolyl]methyl]-1H-1,2,4-triazole-5-thione | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
3-(2-methoxyphenyl)-4-phenyl-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
4-(4-methylphenyl)-3-phenyl-1H-imidazole-2-thione | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
2-cyano-N'-[2,6-dinitro-4-(trifluoromethyl)phenyl]acetohydrazide | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
3-(4-methyl-1,3-dioxan-2-yl)-1-benzopyran-4-one | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
N-[bis(methylthio)methylideneamino]-4-hydroxybenzamide | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
sib 1757 | Leishmania mexicana mexicana | Potency | 6.3096 | 2 | 0 |
apigenin | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
daphnetin | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
chrysoeriol | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
genistein | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
morin | Leishmania mexicana mexicana | Potency | 19.9526 | 2 | 0 |
myricetin | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 0 |
daidzein | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
tranilast | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
4-hydroxyestradiol | Leishmania mexicana mexicana | Potency | 1.0000 | 2 | 0 |
4-hydroxychalcone | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
3-(prop-2-enylthio)-[1,2,4]triazino[5,6-d][3,1]benzoxazepine | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
5,7-dihydroxy-4',6-dimethoxyflavone | Leishmania mexicana mexicana | Potency | 7.9433 | 2 | 0 |
erbstatin | Leishmania mexicana mexicana | Potency | 16.6621 | 3 | 0 |
tyrphostin ag-494 | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
2'-hydroxy-4-methoxychalcone | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
(2e)-3-phenyl-1-(2,3,4,5-tetrahydro-1,6-benzodioxocin-8-yl)prop-2-en-1-one | Leishmania mexicana mexicana | Potency | 28.1838 | 2 | 0 |
styrylquinoline | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
7-hydroxyisoflavone | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 0 |
s-trans,trans-farnesylthiosalicylic acid | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 0 |
dithiazanine iodide | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
quinaldine red | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
2',3,4-trihydroxychalcone | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
chloride of pseudoisocyanine | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
nf023 | Leishmania mexicana mexicana | Potency | 0.3981 | 2 | 0 |
alpha-(p-Methoxyphenyl)-2-pyridineacrylonitrile | Leishmania mexicana mexicana | Potency | 8.9125 | 2 | 0 |
Adenosine 5'-monophosphate monohydrate | Leishmania mexicana mexicana | Potency | 8.8355 | 3 | 0 |
1-(3-methoxyphenyl)-3-[2-(methylthio)phenyl]urea | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |
pd 404182 | Leishmania mexicana mexicana | Potency | 10.0000 | 2 | 0 |
altenusin | Leishmania mexicana mexicana | Potency | 2.8184 | 2 | 0 |
hydralazine 4-anisaldehyde hydrazone | Leishmania mexicana mexicana | Potency | 11.2202 | 2 | 0 |
lissamine rhodamine b | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 0 |
N-[3-[butyl(ethyl)amino]propyl]-2-[6-(4-morpholinylsulfonyl)-3-oxo-1,4-benzothiazin-4-yl]acetamide | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 0 |
5-methyl-5-pentyl-2-phenyl-1,2,4-triazolidine-3-thione | Leishmania mexicana mexicana | Potency | 3.9811 | 2 | 0 |
1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
u 63557a | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 0 |
acid blue 129 | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 0 |
LSM-16789 | Leishmania mexicana mexicana | Potency | 22.3872 | 2 | 0 |