4-phenylbutyric acid has been researched along with Sensitivity and Specificity in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takayanagi, T | 1 |
| Kawai, T | 1 |
| Forrester, SJ | 1 |
| Obama, T | 1 |
| Tsuji, T | 1 |
| Fukuda, Y | 1 |
| Elliott, KJ | 1 |
| Tilley, DG | 1 |
| Davisson, RL | 1 |
| Park, JY | 1 |
| Eguchi, S | 1 |
| Hommes, FA | 1 |
2 other studies available for 4-phenylbutyric acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Disease Models, Animal; Endoplasmic Reticulu | 2015 |
The assay of phenylacetic acid and 4-phenylbutyric acid in physiological fluids.
Topics: Calibration; Gas Chromatography-Mass Spectrometry; Humans; Phenylacetates; Phenylbutyrates; Referenc | 1999 |