Page last updated: 2024-12-08

bisabolol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bisabolol: monocyclic sesquiterpene alcohol with strong bacteriocidal effects, especilly against M. Tuberc.; isolated from seed plant Populus tacamacaha; RN given refers to cpd without isomeric desigation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Kamillosan: drug combination containing chamomile and bisabolol; used to treat dermatitis [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
PopulusgenusA plant genus of the family SALICACEAE. Balm of Gilead is a common name used for P. candicans, or P. gileadensis, or P. jackii, and sometimes also used for ABIES BALSAMEA or for COMMIPHORA.[MeSH]SalicaceaeA plant family of the order MALPIGHIALES, superorder ROSANAE, class MAGNOLIOPSIDA. The leaves are alternate and simple, and staminate (male) flowers consist of one to several stamens; pistillate (female) flowers consist of a single-chambered ovary with several ovules that produce silky seeds.[MeSH]
PopulusgenusA plant genus of the family SALICACEAE. Balm of Gilead is a common name used for P. candicans, or P. gileadensis, or P. jackii, and sometimes also used for ABIES BALSAMEA or for COMMIPHORA.[MeSH]SalicaceaeA plant family of the order MALPIGHIALES, superorder ROSANAE, class MAGNOLIOPSIDA. The leaves are alternate and simple, and staminate (male) flowers consist of one to several stamens; pistillate (female) flowers consist of a single-chambered ovary with several ovules that produce silky seeds.[MeSH]
PopulusgenusA plant genus of the family SALICACEAE. Balm of Gilead is a common name used for P. candicans, or P. gileadensis, or P. jackii, and sometimes also used for ABIES BALSAMEA or for COMMIPHORA.[MeSH]SalicaceaeA plant family of the order MALPIGHIALES, superorder ROSANAE, class MAGNOLIOPSIDA. The leaves are alternate and simple, and staminate (male) flowers consist of one to several stamens; pistillate (female) flowers consist of a single-chambered ovary with several ovules that produce silky seeds.[MeSH]

Cross-References

ID SourceID
PubMed CID1549992
CHEMBL ID1171719
CHEBI ID192031
SCHEMBL ID24988
MeSH IDM0045571
PubMed CID6097621
CHEMBL ID1561544
SCHEMBL ID13220166
MeSH IDM0045571
PubMed CID442343
CHEMBL ID1096927
CHEBI ID125
SCHEMBL ID24989
MeSH IDM0045571

Synonyms (187)

Synonym
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (r*,r*)-
einecs 208-205-9
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-
(r*,r*)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-
(r*,r*)-(1)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphar,1r)-rel-
alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
einecs 246-973-7
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (r*,r*)-
5-hepten-2-ol, 6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-
bisabolol, alpha
bisabolol, .alpha.
CHEMBL1171719 ,
bisabola-1,12-dien-8-ol
racemic alfa-bisabolol
CHEBI:192031
(2r)-6-methyl-2-[(1r)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol
(+)-alpha-bisabolol
bdbm50284328
cas-515-69-5
dtxcid3025964
dtxsid5045964 ,
tox21_111490
AKOS015969722
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-, (alphar,1r)-rel-
36hqn158vc ,
unii-36hqn158vc
d-alpha-bisabolol
(+)-(1'r,2r)-alpha-bisabolol
alpha-bisabolol, (+)-
alpha-bisabolol (+)-form [mi]
unii-105s6i733z
105s6i733z ,
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-, (alphar,1r)-
.alpha.-bisabolol, (+)-
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-penten-1-yl)-, (.alpha.r,1r)-
d-.alpha.-bisabolol
(+)-.alpha.-bisabolol
(+)-(1'r,2r)-.alpha.-bisabolol
.alpha.-bisabolol (+)-form [mi]
S6136
23178-88-3
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl- 3-pentenyl)-, (r*,r*)-
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl- 3-penten-1-yl)-, (.alpha.r,1r)-rel-
(+/-)-.alpha.-bisabolol
.alpha.-bisabolol, (+/-)-
25428-43-7
alpha-bisabolol, (+-)-
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl- 3-pentenyl)-, (.theta.,.theta.)-(+/-)-
.alpha.-bisabolol [mi]
bisabolol, (+/-)-
bisabolol [who-dd]
SCHEMBL24988
NCGC00095252-05
tox21_111490_1
W-105877
(2r)-6-methyl-2-[(1r)-4-methyl-3-cyclohexen-1-yl]-5-hepten-2-ol
RGZSQWQPBWRIAQ-LSDHHAIUSA-N
(2r)-6-methyl-2-(4-methyl-3-cyclohexenyl)-5-heptene-2-ol
mfcd03846910
(+)-a-bisabolol
alpha,4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-(alphar,1r)-3-cyclohexene-1-methanol
(+)-6r,7r-alpha-bisabolol
HY-121222
CS-0081254
(r)-6-methyl-2-((r)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
rel-(r)-6-methyl-2-((r)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
( inverted exclamation marka)-|a-bisabolol
(alphar,1r)-alpha-bisabolol
SDCCGMLS-0066854.P001
BSPBIO_002921
SPECTRUM4_001736
bisabolol
NCGC00095252-01
NCGC00095252-02
KBIOGR_002152
KBIO3_002141
SPECTRUM2_000491
SPECTRUM3_001291
SPBIO_000381
SPECTRUM307057
NCGC00095252-03
(2s)-6-methyl-2-(4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
HMS1923G19
CCG-38711
AKOS015914136
CHEMBL1561544
SCHEMBL13220166
sr-05000002465
SR-05000002465-1
RGZSQWQPBWRIAQ-LOACHALJSA-N
(-)-.alpha.-bisabolol
.alpha.-bisabolol
levomenol
(-)-alpha-bisabolol
23089-26-1
C09621
(-)-alpha-bisabolol, >=93% (gc)
LMPR0103060001
(2s)-6-methyl-2-[(1s)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol
(.alpha.s,1s)-.alpha.-bisabolol
.alpha.-bisabolol (-)-form
CHEMBL1096927
alpha-(-)-bisabolol
chebi:125 ,
fema no. 4666
bisabolol, (-)-.alpha.
.alpha.-bisabolol, (-)-
kamillosan
cas-23089-26-1
dtxsid4042094 ,
NCGC00255987-01
tox21_301375
dtxcid2022094
bdbm50382730
levomenol [inn]
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (s-(theta,theta))-
unii-24we03bx2t
kamilosan
(-)-6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
24we03bx2t ,
bisbalol
alpha-bisabolol (-)-form
einecs 245-423-3
ccris 9081
levomenolum
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphas,1s)-
alpha-bisabolol, l-
levomenolum [inn-latin]
1-alpha-bisabolol
levomenol [who-dd]
levomenol [usp-rs]
bisabolol [vandf]
levomenol [mart.]
bisabolol [inci]
.alpha.-bisabolol (-)-form [mi]
5-hepten-2-ol, 6-methyl-2-(4- methyl-3-cyclohexen-1-yl), (-)-
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-penten-1-yl)-, (.alpha.s,1s)-
(-)-.alpha.-bisabolol (constituent of chamomile) [dsc]
SCHEMBL24989
((-))-6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
[s-(r*,r*)]-.alpha.-bisabolol
.alpha.-bisabolol, l-
5-hepten-2-ol, 6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-, (-)-
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (.alpha.s,1s)-
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, (-)-
l-.alpha.-bisabolol
.alpha.-(-)-bisabolol
3-cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (-)-
[s-(r*,r*)]-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
mfcd03412455
alpha-(-)bisabolol
(-)-alpha-bisabolol, analytical standard
(-)-alpha-bisabolol, primary pharmaceutical reference standard
levomenol, united states pharmacopeia (usp) reference standard
(-)-(4s,8s)-alpha-bisabolol
(-)-a-bisabolol
l-alpha-bisabolol
levomenol, inn
alpha,4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-(alphas,1s)-3-cyclohexene-1-methanol
J-014978
DB13153
(-)-alpha-bisabolol (levomenol)
(-)-alpha-bisabolol(-)-alpha-bisabolol
(-)--bisabolol
Q179896
3-cyclohexene-1-methanol, a,4-dimethyl-a-(4-methyl-3-pentenyl)-,(as,1s)-
HY-N6967
CS-0028206
(s)-6-methyl-2-((s)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
nsc782530
nsc-782530
levomenol; (-)-?-bisabolol
levomenol 100 microg/ml in methanol
(-)- alpha -bisabolol
bisabolol, (-)-alpha
alpha-bisabolol, (-)-
(alphas,1s)-alpha-bisabolol
levomenol (mart.)
(-)-alpha-bisabolol (constituent of chamomile)
levomenolum (inn-latin)
3-cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-, (alphas,1s)-
5-hepten-2-ol, 6-methyl-2-(4-methyl-3-cyclohexen-1-yl), (-)-
purpleu baobab face
levomenol (usp-rs)
EN300-19632355

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Despite being widely used, little is known about its toxic effects on organisms and aquatic environment."( Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos.
Hsiao, CD; Jin, M; Li, X; Liu, K; Men, X; Xiao, Z; Zhang, B; Zhang, S; Zhou, T, 2019
)
0.51

Compound-Compound Interactions

ExcerptReferenceRelevance
" essential oil (EO), both alone and in combination with antimicrobial drugs."( Hirtellina lobelii DC. essential oil, its constituents, its combination with antimicrobial drugs and its mode of action.
El Beyrouthy, M; Eparvier, V; Khoury, M; Ouaini, N; Stien, D, 2019
)
0.51

Bioavailability

ExcerptReferenceRelevance
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019
)
0.51
" In conclusion, gastroprotective effect on ethanol and indomethacin-induced ulcer promoted by (-)-alpha-bisabolol may be associated with an increase of gastric sulfydryl groups bioavailability leading to a reduction of gastric oxidative injury induced by ethanol and indomethacin."( Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms.
Aquino Neto, MR; de França Fonteles, MM; de Sousa, DP; de Sousa, FC; Gomes Silva, MI; Mendes Vasconcelos, SM; Moura Rocha, NF; Moura, BA; Vasconcelos Rios, ER; Venâncio, ET, 2010
)
0.36

Dosage Studied

Dosage of gastric reduced glutathione (GSH) levels. ethanol and indomethacin reduced the content of non-protein sulfhydryl (NP-SH) groups. (-)-alpha-bisabolol significantly decreased the reduction of these levels on ulcer-induced mice, but not in mice without ulcer.

ExcerptRelevanceReference
" Only glycerol showed dose-response and effects potentially better than no treatment."( Anti-irritants I: Dose-response in acute irritation.
Andersen, F; Andersen, KE; Bindslev-Jensen, C; Fullerton, A; Hedegaard, K; Petersen, TK, 2006
)
0.33
" The dose-response effect of 4 alleged AI (nifedipine, (-)-alpha-bisabolol, canola oil and glycerol) was studied on experimentally induced acute irritation in healthy volunteers, and only glycerol showed dose-related response and effects potentially better than no treatment."( Anti-irritants II: Efficacy against cumulative irritation.
Andersen, F; Andersen, KE; Bindslev-Jensen, C; Fullerton, A; Hedegaard, K; Petersen, TK, 2006
)
0.33
" Dosage of gastric reduced glutathione (GSH) levels showed that ethanol and indomethacin reduced the content of non-protein sulfhydryl (NP-SH) groups, while (-)-alpha-bisabolol significantly decreased the reduction of these levels on ulcer-induced mice, but not in mice without ulcer."( Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms.
Aquino Neto, MR; de França Fonteles, MM; de Sousa, DP; de Sousa, FC; Gomes Silva, MI; Mendes Vasconcelos, SM; Moura Rocha, NF; Moura, BA; Vasconcelos Rios, ER; Venâncio, ET, 2010
)
0.36
"We tested ex vivo blasts from 42 acute leukemias (14 Philadelphia-negative and 14 Philadelphia-positive B acute lymphoid leukemias, Ph-/Ph+B-ALL; 14 acute myeloid leukemias, AML) for their sensitivity to α-bisabolol in 24-hour dose-response assays."( Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells.
Bergamini, C; Bonifacio, M; Carcereri de Prati, A; Cavalieri, E; Fato, R; Guardalben, E; Pizzolo, G; Rigo, A; Suzuki, H; Vinante, F, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (93 Product(s))

Product Categories

Product CategoryProducts
Viandes et dérivés, Viandes, Volailles, Canards, Magrets de canard, Aiguillettes de canard1
Plant-based foods and beverages, Plant-based foods, Fats, Vegetable fats, Olive tree products, Vegetable oils, Olive oils1
Aliments et boissons à base de végétaux, Aliments d'origine végétale, Fruits à coques et dérivés, Fruits à coques, Fruits à coques décortiqués, Noix du Brésil, Noix du Brésil décortiquées1
Other2
en:raisins1
Snacks, Sweet snacks, Biscuits and cakes, Cakes, Cooking helpers, Pastry helpers, Baking Mixes, Dessert mixes, Cake mixes1
Beauty & Personal Care80
Baby & Kids Products4
Herbs, Botanicals & Homeopathy2

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Fudge Brownie MixTargetSnacks, Sweet snacks, Biscuits and cakes, Cakes, Cooking helpers, Pastry helpers, Baking Mixes, Dessert mixes, Cake mixesriboflavin,niacin2024-02-09
Acure Radically Rejuvenating SPF 30 Day Cream -- 1.7 fl ozAcureBeauty & Personal Carecaprylyl glycol, ascorbic acid, bisabolol, cetearyl alcohol, tocopherol, panthenol, ethylhexylglycerin, ferulic acid, tocopherol, glycerin, hexylene glycol, niacinamide, squalane2024-11-29 10:47:42
Acure Seriously Soothing SPF 30 Day Cream -- 1.7 fl ozAcureBeauty & Personal Carecaprylyl glycol, bisabolol, cetearyl alcohol, tocopherol, panthenol, ethylhexylglycerin, tocopherol, glycerin, hexylene glycol, niacinamide, squalane2024-11-29 10:47:42
All Terrain Aloe Gel Skin Relief -- 5 fl ozAll TerrainBeauty & Personal Careallantoin, gluconolactone, bisabolol, glycerin, sodium benzoate, squalane2024-11-29 10:47:42
All Terrain Eczema Relief Cream -- 2 fl ozAll TerrainBeauty & Personal Carecitric acid, gluconolactone, bisabolol, citric acid, glycerin, kaolin, triethoxycaprylylsilane, sodium benzoate, squalane, stearyl alcohol2024-11-29 10:47:42
Andalou Naturals 1000 Roses Fortifying Night Cream - Sensitive -- 1.7 ozAndalou NaturalsBeauty & Personal Carebutylene glycol, citric acid, allantoin, benzyl alcohol, bisabolol, cetyl palmitate, citric acid, tocopherol, dehydroacetic acid, panthenol, tocopherol, glycerin, lactic acid, palmitic acid, palmitic acid, sodium benzoate, squalane, titanium dioxide2024-11-29 10:47:42
Andalou Naturals Age Defying Goji Peptide Perfecting Cream -- 1.7 ozAndalou NaturalsBeauty & Personal CareOrange, Allantoin, Vitamin C, Bisabolol, Cetyl Alcohol, CoQ10, Tocopherol, Panthenol, Ethylhexylglycerin, Tocopherol, Glyceryl Stearate, Glyceryl Laurate, Phenethyl Alcohol, Resveratrol, Riboflavin, Stearic Acid, Ubiquinone2024-11-29 10:47:42
Andalou Naturals Brighten & Tighten Hydro Serum Facial Sheet Mask -- 6 fl ozAndalou NaturalsBeauty & Personal Careallantoin, vitamin C, bisabolol, tocopherol, ethylhexylglycerin, tocopherol, vitamin E, phenethyl alcohol2024-11-29 10:47:42
Andalou Naturals CannaCell Beauty Oil -- 1 fl ozAndalou NaturalsBeauty & Personal Carevitamin C, bisabolol, tocopherol, tocopherol, hemp, resveratrol2024-11-29 10:47:42
Andalou Naturals Hyaluronic DMAE Lift & Firm Cream Age Defying -- 1.7 ozAndalou NaturalsBeauty & Personal Careorange, allantoin, vitamin C, bisabolol, CoQ10, tocopherol, dimethylaminoethanol, panthenol, ethylhexylglycerin, tocopherol, glyceryl stearate, phenethyl alcohol, resveratrol, riboflavin, ubiquinone2024-11-29 10:47:42
Andalou Naturals MEN Smooth Glide Shave Cream -- 6 fl ozAndalou NaturalsBeauty & Personal Careallantoin, vitamin C, bisabolol, cetyl alcohol, tocopherol, panthenol, ethylhexylglycerin, tocopherol, hemp, phenoxyethanol, pine, potassium stearate, stearyl alcohol2024-11-29 10:47:42
Andalou Naturals Pure Pore Hydro Serum Facial Sheet Mask -- 0.6 fl ozAndalou NaturalsBeauty & Personal Careallantoin, bisabolol, tocopherol, tocopherol, palmarosa, vitamin E, phenethyl alcohol2024-11-29 10:47:42
Aquaphor Lip Repair Immediate Relief -- 0.35 fl ozAquaphorBeauty & Personal Careglyceryl oleate, ascorbyl palmitate, bisabolol, tocopherol, panthenol, tocopherol, glyceryl stearate, glycerin, magnesium sulfate, Octyldodecanol2024-11-29 10:47:42
Avalon Organics Bath & Shower Gel Nourishing Lavender -- 12 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Citric Acid, Benzyl Alcohol, Bisabolol, Citric Acid, Coumarin, Coumarin, Decyl Glucoside, Limonene, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Bath & Shower Gel Nourishing Lavender -- 32 fl ozAvalon OrganicsBeauty & Personal Carecitric acid, benzyl alcohol, bisabolol, citric acid, coumarin, coumarin, glycerin, limonene, sodium benzoate2024-11-29 10:47:42
Avalon Organics Bath & Shower Gel Refreshing Lemon -- 12 fl ozAvalon OrganicsBeauty & Personal Careglyceryl oleate, orange, citric acid, benzyl alcohol, bisabolol, citral, citric acid, decyl glucoside, limonene, sodium benzoate, sorbitol2024-11-29 10:47:42
Avalon Organics Bath & Shower Gel Revitalizing Peppermint -- 12 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Orange, Citric Acid, Benzyl Alcohol, Bisabolol, Citric Acid, Decyl Glucoside, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Hand & Body Lotion Aloe Unscented -- 32 fl ozAvalon OrganicsBeauty & Personal Carearginine, benzyl alcohol, bisabolol, cetyl alcohol, beta-glucan, glycerin, oat, potassium hydroxide, stearic acid, stearyl alcohol2024-11-29 10:47:42
Avalon Organics Hand & Body Lotion Lavender -- 12 fl ozAvalon OrganicsBeauty & Personal CareArginine, Benzyl Alcohol, Bisabolol, Cetyl Alcohol, Citral, Coumarin, Coumarin, Beta-Glucan, Geraniol, Glycerin, Limonene, Oat, Potassium Hydroxide, Sodium Benzoate, Stearic Acid, Stearyl Alcohol2024-11-29 10:47:42
Avalon Organics Hand & Body Lotion Lavender -- 32 fl ozAvalon OrganicsBeauty & Personal Carearginine, benzyl alcohol, bisabolol, cetyl alcohol, citral, coumarin, coumarin, beta-glucan, geraniol, glycerin, limonene, oat, potassium hydroxide, sodium benzoate, stearic acid, stearyl alcohol2024-11-29 10:47:42
Avalon Organics Hand & Body Lotion Refreshing Lemon -- 12 ozAvalon OrganicsBeauty & Personal Careorange, arginine, benzyl alcohol, bisabolol, cetyl alcohol, cinnamyl alcohol, citral, beta-glucan, geraniol, glycerin, limonene, oat, potassium hydroxide, sodium benzoate, stearic acid, stearyl alcohol2024-11-29 10:47:42
Avalon Organics Hand & Body Lotion Revitalizing Peppermint -- 12 fl ozAvalon OrganicsBeauty & Personal CareOrange, Arginine, Benzyl Alcohol, Bisabolol, Cetyl Alcohol, Citral, Citronellol, Beta-Glucan, Geraniol, Glycerin, Limonene, Oat, Potassium Hydroxide, Sodium Benzoate, Stearic Acid, Stearyl Alcohol2024-11-29 10:47:42
Avalon Organics Scalp Normalizing Shampoo Tea Tree Mint -- 14 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Citric Acid, Terpineol, Benzyl Alcohol, Bisabolol, Camphor, Citric Acid, Citronellol, Decyl Glucoside, Geranyl Acetate, Limonene, Linalyl Acetate, Menthol, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Scalp Treatment Tea Tree Shampoo -- 32 fl ozAvalon OrganicsBeauty & Personal Careorange, citric acid, benzyl alcohol, bisabolol, citric acid, decyl glucoside, beta-glucan, oat, sodium benzoate, sodium sulfate, sorbitol2024-11-29 10:47:42
Avalon Organics Shampoo Clarifying Lemon -- 11 fl ozAvalon OrganicsBeauty & Personal CareOrange, Citric Acid, Benzyl Alcohol, Bisabolol, Citral, Citric Acid, Decyl Glucoside, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Shampoo Nourishing Lavender -- 11 fl ozAvalon OrganicsBeauty & Personal Careglyceryl oleate, citric acid, benzyl alcohol, bisabolol, citric acid, coumarin, coumarin, decyl glucoside, limonene, sodium benzoate, sodium sulfate, sorbitol2024-11-29 10:47:42
Avalon Organics Shampoo Nourishing Lavender -- 32 fl ozAvalon OrganicsBeauty & Personal Carecitric acid, benzyl alcohol, bisabolol, citric acid, coumarin, coumarin, limonene, sodium benzoate2024-11-29 10:47:42
Avalon Organics Shampoo Scalp Treatment Tea Tree -- 11 fl ozAvalon OrganicsBeauty & Personal Careorange, citric acid, bisabolol, citric acid, decyl glucoside, beta-glucan, Oat, sodium benzoate, sodium sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Shampoo Strengthening Peppermint -- 11 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Orange, Citric Acid, Benzyl Alcohol, Bisabolol, Citric Acid, Decyl Glucoside, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Shampoo Volumizing Rosemary -- 11 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Orange, Citric Acid, Benzyl Alcohol, Bisabolol, Citric Acid, Decyl Glucoside, Limonene, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Strengthening Peppermint Conditioner -- 11 ozAvalon OrganicsBeauty & Personal Careorange, arginine, benzyl alcohol, bisabolol, cetyl alcohol, sodium benzoate, sorbitol, stearic acid, stearyl alcohol2024-11-29 10:47:42
Avalon Organics Therapy Medicated Anti-Dandruff Shampoo -- 14 fl ozAvalon OrganicsBeauty & Personal Careorange, benzyl alcohol, bisabolol, glycerin, limonene, menthol, potassium hydroxide, sodium benzoate2024-11-29 10:47:42
Avalon Organics Thickening Shampoo Biotin-B-Complex Therapy -- 32 fl ozAvalon OrganicsBeauty & Personal CareGlyceryl Oleate, Orange, Citric Acid, Benzyl Alcohol, Bisabolol, Beta-Caryophyllene, Citric Acid, Decyl Glucoside, Glycerin, Limonene, Sodium Benzoate, Sodium Sulfate, Sorbitol2024-11-29 10:47:42
Avalon Organics Vitamin C Cleansing Gel -- 6 fl ozAvalon OrganicsBeauty & Personal Careglyceryl oleate, orange, citric acid, ascorbyl glucoside, ascorbic acid, benzyl alcohol, bisabolol, calcium ascorbate, citric acid, decyl glucoside, glycerin, calcium carbonate, sodium benzoate, sodium sulfate, squalane2024-11-29 10:47:42
Avalon Organics Volumizing Rosemary Shampoo -- 32 fl ozAvalon OrganicsBeauty & Personal Careglyceryl oleate, orange, citric acid, benzyl alcohol, bisabolol, citric acid, decyl glucoside, limonene, sodium benzoate, sodium sulfate2024-11-29 10:47:42
Avalon Organics Wrinkle Therapy Firming Body Lotion with CoQ10 & Rosehip -- 8 fl ozAvalon OrganicsBeauty & Personal CareBenzyl Alcohol, Bisabolol, Cetyl Alcohol, Citral, Citronellol, CoQ10, Geraniol, Glycerin, Phenethyl Alcohol, Potassium Hydroxide, Ribose, Sodium Benzoate, Stearic Acid, Stearyl Alcohol, Ubiquinone2024-11-29 10:47:42
Baby Bum Mineral Sunscreen Lotion SPF 50 Fragrance Free -- 3 fl ozBaby BumBaby & Kids Productsbisabolol, cetearyl alcohol, cetyl alcohol, tocopherol, behenyl alcohol, ethylhexylglycerin, tocopherol, sodium gluconate, microcrystalline cellulose, phenoxyethanol2024-11-29 10:47:42
BioRepublic Skincare Lip Mask -- 0.17 fl ozBioRepublic SkincareBeauty & Personal Carecaprylyl glycol, butylene glycol, methylpropanediol, citric acid, ascorbyl palmitate, arginine, bisabolol, carbomer, citric acid, panthenol, hydroxyphenyl propamidobenzoic acid, glycerin, phenoxyethanol, propanediol, sodium citrate, squalane2024-11-29 10:47:42
cocokind Daily Facial Sunscreen Lotion SPF 32 -- 1.07 fl ozcocokindBeauty & Personal CareC8 alcohol, bisabolol, cetearyl alcohol, tocopherol, tocopherol, glycerin, isostearic acid, glyceryl caprylate, sucrose2024-11-29 10:47:42
Comforts Fragrance Free Baby Wipes -- 576 WipesComfortsBaby & Kids Productsbisabolol, glycerin, sodium benzoate2024-11-29 10:47:42
Comforts Sensitive Baby Wipes Soft Packs -- 192 WipesComfortsBaby & Kids Productsbisabolol, sodium benzoate2024-11-29 10:47:42
Dead Sea Naturals Skincare Starter Kit -- 1 KitDead Sea NaturalsBeauty & Personal Carecaprylyl glycol, butylene glycol, aminomethyl propanol, methylpropanediol, citric acid, ascorbyl palmitate, alanine, allantoin, ascorbyl glucoside, ascorbic acid, bisabolol, cetearyl alcohol, cetyl alcohol, cetyl palmitate, chlorphenesin, citric acid, cocamidopropyl betaine, tocopherol, panthenol, pro vitamin B5, ethylhexylglycerin, farnesol, tocopherol, vitamin E, glyceryl stearate, glycerin, glycine, dimethicone, hexyl cinnamal, hydroxyethylcellulose, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, isopropyl myristate, kaolin, lactic acid, linalool, niacinamide, phenoxyethanol, peg-40 stearate, propylene glycol, salicylic acid, beta-sitosterol, sodium benzoate, sodium citrate, sodium hydroxide, sodium lactate, squalene, stearyl alcohol, trehalose, urea, zinc oxide2024-11-29 10:47:42
Every Man Jack Beard + Face Wash - Sandalwood -- 6.7 fl ozEvery Man JackBeauty & Personal Careglyceryl oleate, bisabolol, cocoamidopropyl betaine, decyl glucoside, ethylhexylglycerin, glycerin, linalool, phenoxyethanol, sodium benzoate2024-11-29 10:47:42
Gabriel Lipstick Clay -- 0.13 ozGabrielBeauty & Personal Carebisabolol2024-11-29 10:47:42
Gabriel Lipstick Pomegranate -- 0.13 ozGabrielBeauty & Personal Carebisabolol, retinyl palmitate2024-11-29 10:47:42
Gabriel Lipstick Raisin -- 0.13 ozGabrielBeauty & Personal Carebisabolol, retinyl palmitate2024-11-29 10:47:42
Herban Cowboy Deodorant Wild -- 2.8 ozHerban CowboyBeauty & Personal Careallantoin, bisabolol, ethylhexylglycerin2024-11-29 10:47:42
Herban Cowboy Maximum Protection Deodorant for Her - Blossom -- 2.8 ozHerban CowboyBeauty & Personal Careallantoin, bisabolol, ethylhexylglycerin2024-11-29 10:47:42
Herban Cowboy Maximum Protection Deodorant for Her - Powder -- 2.8 ozHerban CowboyBeauty & Personal Careallantoin, bisabolol, ethylhexylglycerin, glycerin, hydroxyethylcellulose2024-11-29 10:47:42
Herban Cowboy Maximum Protection Deodorant Forest -- 2.8 ozHerban CowboyBeauty & Personal Careallantoin, bisabolol, ethylhexylglycerin2024-11-29 10:47:42
Heritage Store Castor Serum Volumizing Treatment For Brows & Lashes -- 0.42 fl ozHeritage StoreBeauty & Personal Carebiotin, bisabolol, glycerin, maltodextrin2024-11-29 10:47:42
Home Health Goji Berry Facial Cream Fragrance Free -- 4 ozHome HealthBeauty & Personal Carecitric acid, bisabolol, cetyl palmitate, citric acid, dimethyl MEA, panthenol, ethylhexylglycerin, sodium gluconate, glycerin, isopropyl palmitate, niacinamide, retinyl palmitate, Vitamin A, stearyl alcohol2024-11-29 10:47:42
Home Health Hyaluronic Acid Moisturizing Cream Fragrance Free -- 4 ozHome HealthBeauty & Personal Carecitric acid, vitamin C, bisabolol, citric acid, d-alpha tocopherol, and, panthenol, diazolidinyl urea, disodium EDTA, glycerin, dimethicone, vitamin B5, retinyl palmitate, Vitamin A2024-11-29 10:47:42
Jason C Effects Powered By Ester-C Creme -- 2 ozJasonBeauty & Personal Careallantoin, alpha-isomethyl ionone, benzyl alcohol, benzyl benzoate, benzyl salicylate, gluconolactone, bisabolol, calcium ascorbate, cetearyl alcohol, cetyl alcohol, cinnamyl alcohol, citral, coumarin, coumarin, panthenol, glycerin, dimethicone, hexyl cinnamal, hydroxyisohexyl 3-cyclohexene carboxaldehyde, calcium carbonate, limonene, linalool, phenoxyethanol, potassium hydroxide, sodium benzoate, stearic acid, thioctic acid2024-11-29 10:47:42
Life-Flo Cooling Mist - Sage & Mint -- 3.4 fl ozLife-FloHerbs, Botanicals & Homeopathyorange, bisabolol, decyl glucoside, basil, menthol, propanediol2024-11-29 10:47:42
Life-Flo Magnesium Cooling Gel - Sage & Mint -- 3.4 fl ozLife-FloHerbs, Botanicals & Homeopathyorange, bisabolol, dimethyl sulfone, basil, glycerin, maltodextrin, menthol, propanediol2024-11-29 10:47:42
Live P.S. Probiotic 3-Step Skin Care Kit -- 1 KitLive P.S.Beauty & Personal Caregeranium, citric acid, bisabolol, carbomer, chitosan, citric acid, tocopherol, ethylhexylglycerin, tocopherol, glycerin, hemp, sodium hydroxide, squalane2024-11-29 10:47:42
Live P.S. Probiotic Recover Serum -- 1 ozLive P.S.Beauty & Personal Carecitric acid, bisabolol, carbomer, chitosan, citric acid, tocopherol, ethylhexylglycerin, tocopherol, glycerin, hemp, sodium hydroxide, squalane2024-11-29 10:47:42
Mad Hippie Hydrating Facial Mineral Sunscreen SPF 25 -- 2 fl ozMad HippieBeauty & Personal Carecaprylyl glycol, citric acid, bisabolol, cetearyl alcohol, cetyl alcohol, citric acid, tocopherol, behenyl alcohol, ferulic acid, tocopherol, sodium gluconate, glycerin, microcrystalline cellulose, squalane2024-11-29 10:47:42
Mad Hippie Luminizing Facial Mineral Sunscreen SPF 29+ -- 2 fl ozMad HippieBeauty & Personal Carecaprylyl glycol, citric acid, bisabolol, cetearyl alcohol, citric acid, tocopherol, behenyl alcohol, ethyl ferulate, tocopherol, sodium gluconate, glycerin, microcrystalline cellulose, niacinamide, propanediol, quercetin, resveratrol, squalane, titanium dioxide2024-11-29 10:47:42
Mad Hippie Sheer Tint Sun Serum SPF 29 Light-Medium -- 1.02 fl ozMad HippieBeauty & Personal Carecaprylyl glycol, maltose, bisabolol, cetearyl alcohol, tocopherol, decyl glucoside, ethyl ferulate, ferulic acid, tocopherol, sodium gluconate, glycerin, octyldodecanol, resveratrol, squalane2024-11-29 10:47:42
Mad Hippie Sheer Tint Sun Serum SPF 29 Medium-Dark -- 1.02 fl ozMad HippieBeauty & Personal Carecaprylyl glycol, maltose, bisabolol, cetearyl alcohol, tocopherol, decyl glucoside, ethyl ferulate, ferulic acid, tocopherol, sodium gluconate, glycerin, octyldodecanol, resveratrol, squalane2024-11-29 10:47:42
Mad Hippie Ultra Sheer Body SPF 40 -- 4 fl ozMad HippieBeauty & Personal Carecaprylyl glycol, citric acid, bisabolol, cetearyl alcohol, cetyl alcohol, citric acid, tocopherol, behenyl alcohol, tocopherol, sodium gluconate, glycerin, microcrystalline cellulose, quercetin, squalane2024-11-29 10:47:42
Mustela Baby - Child SPF 50 Mineral Sunscreen Stick -- 0.6 ozMustelaBaby & Kids Productsbisabolol, tocopherol, tocopherol2024-11-29 10:47:42
MyChelle Dermaceuticals Ageless Peptide plus Anti-Wrinkle Serum -- 1 fl ozMyChelle DermaceuticalsBeauty & Personal Carecitric acid, bisabolol, citric acid, glycerin, phenoxyethanol, withania somnifera2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Replenishing Solar Defense Sunscreen SPF 50 -- 6 fl ozMyChelle DermaceuticalsBeauty & Personal Carecaprylyl glycol, citric acid, bisabolol, cetearyl alcohol, cetyl alcohol, citric acid, tocopherol, behenyl alcohol, tocopherol, sodium gluconate, glucoside, glycerin, vanillin2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Sun Shield Liquid Sunscreen SPF 30 Light-Medium -- 1 ozMyChelle DermaceuticalsBeauty & Personal Carecaprylyl glycol, maltose, bisabolol, cetearyl alcohol, tocopherol, ethyl ferulate, tocopherol, sodium gluconate, glycerin, octyldodecanol2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Sun Shield Liquid Sunscreen SPF 30 Medium-Dark -- 1 ozMyChelle DermaceuticalsBeauty & Personal Carecaprylyl glycol, maltose, bisabolol, cetearyl alcohol, tocopherol, ethyl ferulate, tocopherol, sodium gluconate, glycerin, octyldodecanol2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Sun Shield Liquid Sunscreen SPF 50 Non-Tinted -- 1 fl ozMyChelle DermaceuticalsBeauty & Personal Carecapryl glycol, citric acid, galactoarabinan, bisabolol, cetearyl alcohol, citric acid, tocopherol, tocopherol, glycerin, glyceryl caprylate2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Sun Shield Stick SPF 50 - Non-Tinted -- 0.52 ozMyChelle DermaceuticalsBeauty & Personal Carebisabolol2024-11-29 10:47:42
MyChelle Dermaceuticals Protect Sun Shield Stick SPF 50 - Tinted -- 0.52 ozMyChelle DermaceuticalsBeauty & Personal Carebisabolol2024-11-29 10:47:42
Nubian Heritage Cruelty-Free Lavender & Wildflowers Hand Cream Lotion with Shea Butter for Dry Skin -- 4 fl ozNubian HeritageBeauty & Personal Careallantoin, bisabolol, cetearyl alcohol, cetyl alcohol, glyceryl stearate, glycerin, glyceryl caprylate2024-11-29 10:47:42
Pacifica Glow Baby Vitaglow Face Lotion -- 1.7 fl ozPacificaBeauty & Personal Careorange, ascorbic acid, bisabolol, cetyl alcohol, tocopherol, ethylhexylglycerin, tocopherol, vitamin E, glyceryl stearate, glycerin, phenoxyethanol, stearic acid2024-11-29 10:47:42
SheaMoisture African Black Soap Facial Wash & Scrub to Clarify Blemish-Prone Skin -- 4 ozSheaMoistureBeauty & Personal Carecaprylyl glycol, bisabolol, cetyl alcohol, palm, decyl glucoside, panthenol, glycerin, glyceryl laurate, myristic acid, myristyl alcohol, potassium hydroxide, salicylic acid, sodium benzoate, stearic acid2024-11-29 10:47:42
SheaMoisture African Black Soap with Shea Butter Clarifying Facial Wash & Scrub for Problem Skin -- 1.5 ozSheaMoistureBeauty & Personal Careorange, chamomile, bisabolol, decyl glucoside, panthenol, glycerine, myristic acid, vitamin B-5, salicylic acid, stearic acid2024-11-29 10:47:42
SheaMoisture Silicone-Free Manuka Honey & Yogurt Multi-Action Leave-in Hair Care for Damaged Hair -- 8 fl ozSheaMoistureBeauty & Personal Carecaprylyl glycol, benzoic acid, bisabolol, cetyl alcohol, tocopherol, triethyl citrate, tocopherol, glycerin, stearyl alcohol2024-11-29 10:47:42
Shikai Healthy Glow Daily Moisturizing Lotion with CBD & Vitamin C -- 1.7 ozShikaiBeauty & Personal Careorange, vitamin C, betaine, bisabolol, cannabidiol, cetyl alcohol, cetyl palmitate, and, dimethicone, phenoxyethanol2024-11-29 10:47:42
Shikai Very Clean Body Barrier Cream Honey Almond -- 4.5 fl ozShikaiBeauty & Personal Carebisabolol, cetyl alcohol, tocopherol, and, panthenol, pro-vitamin B5, behenyl alcohol, tocopherol, vitamin E, glyceryl stearate, glycerin, vitamin B3, niacinamide, phenoxyethanol2024-11-29 10:47:42
Sun Bum Mineral SPF 30 Sunscreen Lip Balm -- 0.15 ozSun BumBeauty & Personal Carebisabolol, tocopherol, tocopherol, isostearic acid, glyceryl caprylate2024-11-29 10:47:42
Sun Bum Mineral SPF 50 Sunscreen Lotion -- 3 fl ozSun BumBeauty & Personal Carebisabolol, cetearyl alcohol, cetyl alcohol, tocopherol, behenyl alcohol, ethylhexylglycerin, tocopherol, sodium gluconate, microcrystalline cellulose, phenoxyethanol2024-11-29 10:47:42
The Honey Pot Sensual Stimulating Serum -- 1 fl ozThe Honey PotBeauty & Personal Careiodopropynyl butylcarbamate, allantoin, bisabolol, chlorphenesin, vitamin E, vitamin E, dimethicone, hydroxyethylcellulose, propylene glycol2024-11-29 10:47:42
The Seaweed Bath Co Hydrate & Protect Dewy Skin Face Lotion SPF 30 -- 2 fl ozThe Seaweed Bath CoBeauty & Personal Carecitric acid, allantoin, vitamin C, betaine, bisabolol, citric acid, vitamin E, basil, vitamin E, glyceryl stearate, glycerin, glyceryl caprylate, niacinamide, squalane2024-11-29 10:47:42
Zuzu Luxe Precision Liquid Liner Amethyst -- 0.1 fl ozZuzu LuxeBeauty & Personal Carebisabolol, cetyl alcohol, hectorite, sorbitol2024-11-29 10:47:42
Zuzu Luxe Precision Liquid Liner Black Pearl -- 0.1 fl ozZuzu LuxeBeauty & Personal Carebisabolol, cetyl alcohol, hectorite, sorbitol2024-11-29 10:47:42
Zuzu Luxe Precision Liquid Liner Raven -- 0.1 fl ozZuzu LuxeBeauty & Personal Carebisabolol, cetyl alcohol, hectorite, sorbitol2024-11-29 10:47:42
Zuzu Luxe Precision Liquid Liner Storm -- 0.1 fl ozZuzu LuxeBeauty & Personal Carebisabolol, cetyl alcohol, hectorite, sorbitol2024-11-29 10:47:42
Zuzu Luxe Precision Liquid Liner Taureg -- 0.1 fl ozZuzu LuxeBeauty & Personal Carebisabolol, cetyl alcohol, hectorite, sorbitol2024-11-29 10:47:42

Drug Classes (1)

ClassDescription
sesquiterpenoidAny terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
sesquiterpenoidAny terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (36)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency38.90180.01237.983543.2770AID1645841
farnesoid X nuclear receptorHomo sapiens (human)Potency13.33220.375827.485161.6524AID743220
pregnane X nuclear receptorHomo sapiens (human)Potency29.84930.005428.02631,258.9301AID1346982
GVesicular stomatitis virusPotency27.54040.01238.964839.8107AID1645842
cytochrome P450 2D6Homo sapiens (human)Potency38.90180.00108.379861.1304AID1645840
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency18.99590.057821.109761.2679AID1159528
Interferon betaHomo sapiens (human)Potency27.54040.00339.158239.8107AID1645842
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency27.54040.01238.964839.8107AID1645842
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency27.54040.01238.964839.8107AID1645842
cytochrome P450 2C9, partialHomo sapiens (human)Potency27.54040.01238.964839.8107AID1645842
15-lipoxygenase, partialHomo sapiens (human)Potency12.58930.012610.691788.5700AID887
USP1 protein, partialHomo sapiens (human)Potency89.12510.031637.5844354.8130AID504865
mitogen-activated protein kinase 1Homo sapiens (human)Potency5.01190.039816.784239.8107AID995
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency39.81070.031610.279239.8107AID884; AID885
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
GABA theta subunitRattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency39.81071.000012.224831.6228AID885
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency61.64480.000214.376460.0339AID720692
estrogen nuclear receptor alphaHomo sapiens (human)Potency54.48270.000229.305416,493.5996AID743079
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency26.51850.057821.109761.2679AID1159526; AID1159528
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency30.63790.000323.4451159.6830AID743067
heat shock protein beta-1Homo sapiens (human)Potency61.64480.042027.378961.6448AID743210
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)IC50 (µMol)3.10000.00204.15279.9000AID1612108
Signal transducer and activator of transcription 3Homo sapiens (human)IC50 (µMol)73.00000.02304.13789.9800AID660829
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (153)

Processvia Protein(s)Taxonomy
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell activation involved in immune responseInterferon betaHomo sapiens (human)
cell surface receptor signaling pathwayInterferon betaHomo sapiens (human)
cell surface receptor signaling pathway via JAK-STATInterferon betaHomo sapiens (human)
response to virusInterferon betaHomo sapiens (human)
positive regulation of autophagyInterferon betaHomo sapiens (human)
cytokine-mediated signaling pathwayInterferon betaHomo sapiens (human)
natural killer cell activationInterferon betaHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT proteinInterferon betaHomo sapiens (human)
cellular response to interferon-betaInterferon betaHomo sapiens (human)
B cell proliferationInterferon betaHomo sapiens (human)
negative regulation of viral genome replicationInterferon betaHomo sapiens (human)
innate immune responseInterferon betaHomo sapiens (human)
positive regulation of innate immune responseInterferon betaHomo sapiens (human)
regulation of MHC class I biosynthetic processInterferon betaHomo sapiens (human)
negative regulation of T cell differentiationInterferon betaHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIInterferon betaHomo sapiens (human)
defense response to virusInterferon betaHomo sapiens (human)
type I interferon-mediated signaling pathwayInterferon betaHomo sapiens (human)
neuron cellular homeostasisInterferon betaHomo sapiens (human)
cellular response to exogenous dsRNAInterferon betaHomo sapiens (human)
cellular response to virusInterferon betaHomo sapiens (human)
negative regulation of Lewy body formationInterferon betaHomo sapiens (human)
negative regulation of T-helper 2 cell cytokine productionInterferon betaHomo sapiens (human)
positive regulation of apoptotic signaling pathwayInterferon betaHomo sapiens (human)
response to exogenous dsRNAInterferon betaHomo sapiens (human)
B cell differentiationInterferon betaHomo sapiens (human)
natural killer cell activation involved in immune responseInterferon betaHomo sapiens (human)
adaptive immune responseInterferon betaHomo sapiens (human)
T cell activation involved in immune responseInterferon betaHomo sapiens (human)
humoral immune responseInterferon betaHomo sapiens (human)
positive regulation of T cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
adaptive immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of T cell anergyHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
defense responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
detection of bacteriumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-12 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of interleukin-6 productionHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protection from natural killer cell mediated cytotoxicityHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
innate immune responseHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
regulation of dendritic cell differentiationHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class IbHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol phosphate metabolic processInositol hexakisphosphate kinase 1Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
negative regulation of cold-induced thermogenesisInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol phosphate biosynthetic processInositol hexakisphosphate kinase 1Homo sapiens (human)
negative regulation of tumor necrosis factor productionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
response to hypoxiaNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of protein phosphorylationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
monoatomic ion transportNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
calcium ion transportNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
intracellular calcium ion homeostasisNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
signal transductionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
synaptic transmission, cholinergicNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
learning or memoryNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
memoryNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
short-term memoryNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of cell population proliferationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
negative regulation of tumor necrosis factor productionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
monoatomic ion transmembrane transportNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
response to nicotineNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of MAPK cascadeNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of angiogenesisNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
synapse organizationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
cognitionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
sensory processingNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of protein metabolic processNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
excitatory postsynaptic potentialNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascadeNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
calcium ion transmembrane transportNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
acetylcholine receptor signaling pathwayNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
dendritic spine organizationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
modulation of excitatory postsynaptic potentialNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
dendrite arborizationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of long-term synaptic potentiationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of amyloid-beta formationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
negative regulation of amyloid-beta formationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
regulation of amyloid precursor protein catabolic processNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
response to amyloid-betaNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
response to acetylcholineNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
regulation of amyloid fibril formationNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of CoA-transferase activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of excitatory postsynaptic potentialNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
regulation of membrane potentialNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
chemical synaptic transmissionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
positive regulation of vascular endothelial growth factor productionSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of transcription by RNA polymerase IISignal transducer and activator of transcription 3Homo sapiens (human)
temperature homeostasisSignal transducer and activator of transcription 3Homo sapiens (human)
eye photoreceptor cell differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
regulation of DNA-templated transcriptionSignal transducer and activator of transcription 3Homo sapiens (human)
regulation of transcription by RNA polymerase IISignal transducer and activator of transcription 3Homo sapiens (human)
protein import into nucleusSignal transducer and activator of transcription 3Homo sapiens (human)
inflammatory responseSignal transducer and activator of transcription 3Homo sapiens (human)
signal transductionSignal transducer and activator of transcription 3Homo sapiens (human)
transforming growth factor beta receptor signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STATSignal transducer and activator of transcription 3Homo sapiens (human)
nervous system developmentSignal transducer and activator of transcription 3Homo sapiens (human)
cell population proliferationSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of cell population proliferationSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of autophagySignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of gene expressionSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of gene expressionSignal transducer and activator of transcription 3Homo sapiens (human)
phosphorylationSignal transducer and activator of transcription 3Homo sapiens (human)
cytokine-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
sexual reproductionSignal transducer and activator of transcription 3Homo sapiens (human)
cell differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of cell migrationSignal transducer and activator of transcription 3Homo sapiens (human)
intracellular receptor signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
response to estradiolSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of interleukin-1 beta productionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of interleukin-10 productionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of interleukin-6 productionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of interleukin-8 productionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of tumor necrosis factor productionSignal transducer and activator of transcription 3Homo sapiens (human)
cellular response to hormone stimulusSignal transducer and activator of transcription 3Homo sapiens (human)
leptin-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
somatic stem cell population maintenanceSignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-15-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-2-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-9-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-11-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
regulation of multicellular organism growthSignal transducer and activator of transcription 3Homo sapiens (human)
glucose homeostasisSignal transducer and activator of transcription 3Homo sapiens (human)
eating behaviorSignal transducer and activator of transcription 3Homo sapiens (human)
mRNA transcription by RNA polymerase IISignal transducer and activator of transcription 3Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transductionSignal transducer and activator of transcription 3Homo sapiens (human)
cellular response to leptin stimulusSignal transducer and activator of transcription 3Homo sapiens (human)
response to leptinSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of erythrocyte differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of Notch signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of angiogenesisSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of glycolytic processSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of DNA-templated transcriptionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of transcription by RNA polymerase IISignal transducer and activator of transcription 3Homo sapiens (human)
astrocyte differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of inflammatory responseSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activitySignal transducer and activator of transcription 3Homo sapiens (human)
regulation of cell cycleSignal transducer and activator of transcription 3Homo sapiens (human)
radial glial cell differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
retinal rod cell differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
regulation of feeding behaviorSignal transducer and activator of transcription 3Homo sapiens (human)
growth hormone receptor signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STATSignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-6-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
T-helper 17 type immune responseSignal transducer and activator of transcription 3Homo sapiens (human)
T-helper 17 cell lineage commitmentSignal transducer and activator of transcription 3Homo sapiens (human)
energy homeostasisSignal transducer and activator of transcription 3Homo sapiens (human)
cellular response to interleukin-17Signal transducer and activator of transcription 3Homo sapiens (human)
cell surface receptor signaling pathway via STATSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of inflammatory response to woundingSignal transducer and activator of transcription 3Homo sapiens (human)
interleukin-10-mediated signaling pathwaySignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of cytokine production involved in inflammatory responseSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of miRNA transcriptionSignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of metalloendopeptidase activitySignal transducer and activator of transcription 3Homo sapiens (human)
positive regulation of vascular endothelial cell proliferationSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of primary miRNA processingSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of stem cell differentiationSignal transducer and activator of transcription 3Homo sapiens (human)
negative regulation of neuron migrationSignal transducer and activator of transcription 3Homo sapiens (human)
regulation of cell population proliferationSignal transducer and activator of transcription 3Homo sapiens (human)
response to peptide hormoneSignal transducer and activator of transcription 3Homo sapiens (human)
defense responseSignal transducer and activator of transcription 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (45)

Processvia Protein(s)Taxonomy
cytokine activityInterferon betaHomo sapiens (human)
cytokine receptor bindingInterferon betaHomo sapiens (human)
type I interferon receptor bindingInterferon betaHomo sapiens (human)
protein bindingInterferon betaHomo sapiens (human)
chloramphenicol O-acetyltransferase activityInterferon betaHomo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
signaling receptor bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
peptide antigen bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
TAP bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
protein-folding chaperone bindingHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol heptakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
protein bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
ATP bindingInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 1-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol hexakisphosphate 3-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activityInositol hexakisphosphate kinase 1Homo sapiens (human)
amyloid-beta bindingNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
monoatomic ion channel activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
calcium channel activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
protein bindingNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
acetylcholine receptor activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
toxic substance bindingNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
chloride channel regulator activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
acetylcholine-gated monoatomic cation-selective channel activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
acetylcholine bindingNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
protein homodimerization activityNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
transcription cis-regulatory region bindingSignal transducer and activator of transcription 3Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingSignal transducer and activator of transcription 3Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificSignal transducer and activator of transcription 3Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificSignal transducer and activator of transcription 3Homo sapiens (human)
DNA bindingSignal transducer and activator of transcription 3Homo sapiens (human)
DNA-binding transcription factor activitySignal transducer and activator of transcription 3Homo sapiens (human)
nuclear receptor activitySignal transducer and activator of transcription 3Homo sapiens (human)
signaling receptor bindingSignal transducer and activator of transcription 3Homo sapiens (human)
protein bindingSignal transducer and activator of transcription 3Homo sapiens (human)
protein kinase bindingSignal transducer and activator of transcription 3Homo sapiens (human)
protein phosphatase bindingSignal transducer and activator of transcription 3Homo sapiens (human)
chromatin DNA bindingSignal transducer and activator of transcription 3Homo sapiens (human)
signaling adaptor activitySignal transducer and activator of transcription 3Homo sapiens (human)
identical protein bindingSignal transducer and activator of transcription 3Homo sapiens (human)
protein homodimerization activitySignal transducer and activator of transcription 3Homo sapiens (human)
protein dimerization activitySignal transducer and activator of transcription 3Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingSignal transducer and activator of transcription 3Homo sapiens (human)
primary miRNA bindingSignal transducer and activator of transcription 3Homo sapiens (human)
lncRNA bindingSignal transducer and activator of transcription 3Homo sapiens (human)
DNA-binding transcription factor bindingSignal transducer and activator of transcription 3Homo sapiens (human)
RNA sequestering activitySignal transducer and activator of transcription 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (31)

Processvia Protein(s)Taxonomy
extracellular spaceInterferon betaHomo sapiens (human)
extracellular regionInterferon betaHomo sapiens (human)
Golgi membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
endoplasmic reticulumHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
Golgi apparatusHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
cell surfaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
ER to Golgi transport vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
secretory granule membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
phagocytic vesicle membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
early endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
recycling endosome membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular exosomeHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
lumenal side of endoplasmic reticulum membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
MHC class I protein complexHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
extracellular spaceHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
external side of plasma membraneHLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)
fibrillar centerInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
cytosolInositol hexakisphosphate kinase 1Homo sapiens (human)
nucleusInositol hexakisphosphate kinase 1Homo sapiens (human)
cytoplasmInositol hexakisphosphate kinase 1Homo sapiens (human)
plasma membraneGamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)
plasma membraneGamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)
plasma membraneGamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)
plasma membraneNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
membraneNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
plasma membrane raftNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
postsynaptic membraneNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
postsynapseNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
acetylcholine-gated channel complexNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
plasma membraneNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
neuron projectionNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
synapseNeuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)
nucleusSignal transducer and activator of transcription 3Homo sapiens (human)
nucleusSignal transducer and activator of transcription 3Homo sapiens (human)
nucleoplasmSignal transducer and activator of transcription 3Homo sapiens (human)
cytoplasmSignal transducer and activator of transcription 3Homo sapiens (human)
cytosolSignal transducer and activator of transcription 3Homo sapiens (human)
plasma membraneSignal transducer and activator of transcription 3Homo sapiens (human)
RNA polymerase II transcription regulator complexSignal transducer and activator of transcription 3Homo sapiens (human)
chromatinSignal transducer and activator of transcription 3Homo sapiens (human)
transcription regulator complexSignal transducer and activator of transcription 3Homo sapiens (human)
cytoplasmSignal transducer and activator of transcription 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (191)

Assay IDTitleYearJournalArticle
AID1347100qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347090qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347407qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347099qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347091qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347093qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID1347102qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347424RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347096qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347107qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347105qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347104qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347106qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347425Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347790Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as protection against amyloid beta (25 to 35 residues)-induced apoptosis by measuring early apoptotic cells at 5 ug/ml by Annexin V-FITC/propidium
AID1347773Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregation at 5 ug/ml after 24 to 48 hrs by ThT-based fluorescence spectroscopic method
AID1347786Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as increase in cell viability at 2 to 10 ug/ml preincubated for 2 hrs followed by amyloid beta (25 to 35 residues) addition measured after 24 hrs b
AID1347775Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregation at 5 ug/ml after 24 to 48 hrs by thioflavin T dye based confocal laser scanning microscopy
AID1347780Disaggregation of amyloid beta (25 to 35 residues) (unknown origin) preformed fibrils at 5 ug/ml after 96 hrs to 9 days by phosphotungstic acid staining based transmission electron microscopy
AID1347779Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregation at 5 ug/ml after 24 to 48 hrs by phosphotungstic acid staining based transmission electron microscopy
AID1347782Disaggregation of amyloid beta (25 to 35 residues) (unknown origin) preformed fibrils at 5 ug/ml after 96 hrs to 9 days by FTIR spectroscopy
AID1347797Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as cell survival at 5 ug/ml after 1 to 3 weeks by clonogenic assay (Rvb = 25%)
AID1347792Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as protection against amyloid beta (25 to 35 residues)-induced apoptosis by measuring necrotic cells at 5 ug/ml by Annexin V-FITC/propidium iodide
AID1347781Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregation at 5 ug/ml after 24 to 48 hrs by FTIR spectroscopy
AID1347774Disaggregation of amyloid beta (25 to 35 residues) (unknown origin) preformed fibrils at 5 ug/ml after 96 hrs to 9 days by ThT-based fluorescence spectroscopic method
AID1347791Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as protection against amyloid beta (25 to 35 residues)-induced apoptosis by measuring late apoptotic cells at 5 ug/ml by Annexin V-FITC/propidium i
AID1347787Inhibition of AChE (unknown origin) preincubated for 45 mins followed by ATCI substrate addition measured for 3 mins
AID1347776Disaggregation of amyloid beta (25 to 35 residues) (unknown origin) preformed fibrils at 5 ug/ml after 96 hrs to 9 days by thioflavin T dye based confocal laser scanning microscopy
AID1347785Inhibition of amyloid beta (25 to 35 residues) (unknown origin)-induced toxicity in rat PC12 cells assessed as protection against amyloid beta (25 to 35 residues)-induced apoptosis by measuring viable cells at 5 ug/ml by Annexin V-FITC/propidium iodide st
AID504749qHTS profiling for inhibitors of Plasmodium falciparum proliferation2011Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
AID1333503Toxicity in Syrian hamster assessed as pain at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333544Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as spleen weight at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 178.8 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID490496Cytotoxicity against human UACC62 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333542Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as spleen weight at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 178.2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333530Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALP levels at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333514Toxicity in Syrian hamster assessed as mean serum ALT levels at 500 mg/kg administered through oral gavage for 28 days (Rvb = 82.2 +/- 4.8 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090789Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 6 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090780Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition at 0.3 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333499Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in foodpad skin at 5 % administered once daily tropically on footpad for 3 weeks starting at week 7 po2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478090Cytotoxicity against HUVEC at 0.35 uM after 72 hrs by trypan blue dye exclusion test relative to control2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID490499Cytotoxicity against human NCI-H460 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333524Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum creatinine levels at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478084Cytotoxicity against HUVEC at 5 uM after 6 hrs by Trypan blue dye exclusion test2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333523Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum creatinine levels at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dos2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090782Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 10 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID478089Cytotoxicity against HUVEC at 0.25 uM after 72 hrs by trypan blue dye exclusion test relative to control2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID490502Cytotoxicity against human HT-29 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333506Toxicity in Syrian hamster assessed as mean serum AST levels at 5 % administered tropically on footpad for 28 days (Rvb = 83.4 +/- 4.2 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID490501Cytotoxicity against human OVCAR-3 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1090788Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 8 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333501Toxicity in Syrian hamster assessed as diarrhea at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333543Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as spleen weight at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 178.8 +/2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333529Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALP levels at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090799Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 4 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID490503Cytotoxicity against human K562 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID358270Growth inhibition of mouse 3T3 cells2001Journal of natural products, Oct, Volume: 64, Issue:10
(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.
AID1333507Toxicity in Syrian hamster assessed as mean serum AST levels at 500 mg/kg administered through oral gavage for 28 days (Rvb = 83.4 +/- 4.2 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333563Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in liver at 1 % administered once daily tropically on footpad for 3 weeks starting at week 7 post infe2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1333559Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as redness at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or measured 1 we2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090804Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 4 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090785Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 2 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333570Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in spleen at 5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post inf2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478099Induction of apoptosis in HUVEC assessed as cytochrome C release at 5 uM after 24 hrs by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID478100Induction of apoptosis in HUVEC assessed as procaspase3 activation at 5 uM after 24 hrs by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID478086Induction of apoptosis in HUVEC assessed as procaspase3 activation at 5 uM after 4 hrs by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID490500Cytotoxicity against human PCO3 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333535Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as urea levels at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 32.5 +2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333554Toxicity in Syrian hamster assessed as change in body weight at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333540Toxicity in Syrian hamster assessed as spleen weight at 5 % administered tropically on footpad for 28 days (Rvb = 179.4 +/- 19.8 mg)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478091Cytotoxicity against HUVEC at 0.5 uM after 72 hrs by trypan blue dye exclusion test relative to control2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1090777Antifungal activity against Colletotrichum fragariae assessed as growth inhibition at 0.3 to 30 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333553Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as liver weight at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333515Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALT levels at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rv2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333521Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum creatinine levels at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last d2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090776Antifungal activity against Colletotrichum gloeosporioides assessed as growth inhibition at 0.3 to 30 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090779Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition at 3.0 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333537Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as urea levels at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 32.5 +/-2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090775Antifungal activity against Phomopsis obscurans assessed as growth inhibition at 0.3 to 30 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090781Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 12 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333551Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as liver weight at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 3.3 +/-2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333517Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALT levels at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333562Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in liver at 200 mg administered once daily through oral gavage for 3 weeks starting at week 7 post inf2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333534Toxicity in Syrian hamster assessed as urea levels at 500 mg/kg administered through oral gavage for 28 days (Rvb = 33.2 +/- 2.8 mg/dl)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333560Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as change in body weight at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID660829Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after 6 hrs2012Journal of natural products, Mar-23, Volume: 75, Issue:3
STAT-3 inhibitory bisabolanes from Carthamus glaucus.
AID478085Induction of apoptosis in HUVEC assessed as cytochrome C release at 5 uM after 4 hrs by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333571Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in spleen at 2 mg/kg administered intralesionally once daily on footpad for 3 weeks starting at week 72016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID358269Cicatrizant activity in mouse assessed as wound healing by tensile strength method2001Journal of natural products, Oct, Volume: 64, Issue:10
(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.
AID1333495Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in lesion thickness at 5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post infection 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478098Induction of apoptosis in HUVEC assessed as effect on bax protein level after 1 hr by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333561Toxicity in po dosed dog2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333492Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in lesion thickness at 200 mg administered once daily through oral gavage for 3 weeks starting at week 7 post infection2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333528Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALP levels at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rv2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333513Toxicity in Syrian hamster assessed as mean serum ALT levels at 5 % administered tropically on footpad for 28 days (Rvb = 82.2 +/- 4.8 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333572Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in amastigote levels in foodpad skin macerate at 200 mg administered once daily through oral gavage for 3 weeks startin2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090783Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 8 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333511Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum AST levels at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333556Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as stress at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or measured 1 wee2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333525Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum creatinine levels at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post l2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID490497Cytotoxicity against human MCF7 cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333498Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in foodpad skin at 2.5 % administered once daily tropically on footpad for 3 weeks starting at week 7 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333508Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum AST levels at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rv2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333564Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in liver at 2.5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post in2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333568Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in spleen at 1 % administered once daily tropically on footpad for 3 weeks starting at week 7 post inf2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333516Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALT levels at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID490498Cytotoxicity against human NCI/ADR cells by sulforhodamine B assay2010European journal of medicinal chemistry, Jul, Volume: 45, Issue:7
Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
AID1333555Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as diarrhea at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or measured 1 w2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090778Antifungal activity against Colletotrichum acutatum assessed as growth inhibition at 0.3 to 30 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090801Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 4 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333527Toxicity in Syrian hamster assessed as mean serum ALP levels at 500 mg/kg administered through oral gavage for 28 days (Rvb = 14.4 +/- 2 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333557Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as pain at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or measured 1 week 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333550Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as liver weight at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 3.3 +/- 02016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333493Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in lesion thickness at 1 % administered once daily tropically on footpad for 3 weeks starting at week 7 post infection 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090790Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 2 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333509Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum AST levels at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333504Toxicity in Syrian hamster assessed as footpad edema at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333552Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as liver weight at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 3.3 +/- 02016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090784Antifungal activity against Colletotrichum gloeosporioides assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 6 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333539Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as urea levels at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 32016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333566Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in liver at 2 mg/kg administered intralesionally once daily on footpad for 3 weeks starting at week 7 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333569Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in spleen at 2.5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post i2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1612107Cytotoxicity against ALL/AML patient derived primary leukemia cells after 24 hrs by LDH release assay2018European journal of medicinal chemistry, Sep-05, Volume: 157Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus.
AID478096Antiangiogenic activity against HUVEC assessed as inhibition of capillary tube organization at 0.5 uM after 4 hrs2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1090795Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 2 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID660830Inhibition of TNFalpha-induced NF-kappaB activation in human HIV-1-LTR-luc 5.1 cells treated 30 mins before TNFalpha challenge measured after 6 hrs2012Journal of natural products, Mar-23, Volume: 75, Issue:3
STAT-3 inhibitory bisabolanes from Carthamus glaucus.
AID1333520Toxicity in Syrian hamster assessed as mean serum creatinine levels at 500 mg/kg administered through oral gavage for 28 days (Rvb = 0.21 +/- 0.2 mg/dl)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478087Induction of apoptosis in HUVEC assessed as down-regulation of Bcl2 protein level at 5 uM after 0.5 hr by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333502Toxicity in Syrian hamster assessed as stress at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333494Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in lesion thickness at 2.5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post infectio2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090787Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 10 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333522Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum creatinine levels at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090786Antifungal activity against Colletotrichum fragariae assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 12 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1333510Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum AST levels at 2.5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333518Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALT levels at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1612108Antagonist activity at human alpha7 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced currents at -70 mV holding potential by electrophysiology2018European journal of medicinal chemistry, Sep-05, Volume: 157Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus.
AID1090791Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 12 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID478097Cytotoxicity against HUVEC assessed as change in cell number at 25 uM after 72 hrs by trypan blue dye exclusion test2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1090793Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 8 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID478092Induction of apoptosis in HUVEC assessed as procaspase3 activation at 0.25 uM after 4 hrs by Western blot analysis2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID478088Cytotoxicity against HUVEC at 0.15 uM after 72 hrs by trypan blue dye exclusion test relative to control2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333519Toxicity in Syrian hamster assessed as mean serum creatinine levels at 5 % administered tropically on footpad for 28 days (Rvb = 0.21 +/- 0.2 mg/dl)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1090774Antifungal activity against Fusarium oxysporum assessed as growth inhibition at 0.3 to 30 uM after 72 hr by 96-well microdilution broth assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333512Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum AST levels at 2 mg/kg administered intralesionally once daily on footpad for 3 weeks starting at week 7 post infection measured 1 week po2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333548Toxicity in Syrian hamster assessed as liver weight at 500 mg/kg administered through oral gavage for 28 days (Rvb = 4.1 +/- 0.7 g)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478093Antiangiogenic activity in HUVEC assessed as decrease in cell migration at 0.25 uM after 4 hrs in the presence of FGF2 relative to control2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333541Toxicity in Syrian hamster assessed as spleen weight at 500 mg/kg administered through oral gavage for 28 days (Rvb = 179.4 +/- 19.8 mg)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333565Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in liver at 5 % administered once daily tropically on footpad for 3 weeks starting at week 7 post infe2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333532Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALP levels at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dos2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333505Toxicity in Syrian hamster assessed as redness at 500 mg/kg, po or 5 % administered tropically on footpad for 28 days2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478095Angiogenic activity against HUVEC assessed as organization of cells in a capillary like structure at 0.25 uM after 4 hrs2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1090794Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 6 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1090792Antifungal activity against Colletotrichum acutatum assessed as size of growth inhibitory zone at concentration of 2 mM in volume of 10 ul of acetone measured after 4 days by TLC based direct bioautography assay2007Journal of agricultural and food chemistry, Oct-17, Volume: 55, Issue:21
Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
AID1333531Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALP levels at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333490Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as mean serum ALT levels at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dos2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333549Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as liver weight at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 3.3 +2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID478094Angiogenic activity against HUVEC assessed as organization of cells in a capillary like structure at 0.1 uM after 4 hrs2010Journal of natural products, Apr-23, Volume: 73, Issue:4
Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
AID1333533Toxicity in Syrian hamster assessed as urea levels at 5 % administered tropically on footpad for 28 days (Rvb = 33.2 +/- 2.8 mg/dl)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333567Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in spleen at 200 mg administered once daily through oral gavage for 3 weeks starting at week 7 post in2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333497Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in foodpad skin at 1 % administered once daily tropically on footpad for 3 weeks starting at week 7 po2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333558Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as footpad edema at 200 mg/kg administered through oral gavage for 3 weeks starting at week 7 post infection measured during compound dosing or measure2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333538Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as urea levels at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 32.5 +/- 02016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333547Toxicity in Syrian hamster assessed as liver weight at 5 % administered tropically on footpad for 28 days (Rvb = 4.1 +/- 0.7 g)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333526Toxicity in Syrian hamster assessed as mean serum ALP levels at 5 % administered tropically on footpad for 28 days (Rvb = 14.4 +/- 2 U/L)2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333546Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as spleen weight at 2 mg/kg administered intralesionally on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb =2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333491Antileishmanial activity against Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes infected in Syrian hamster assessed as reduction in parasite load in foodpad skin at 200 mg administered once daily through oral gavage for 3 weeks starting at week 7 p2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333545Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as spleen weight at 5 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 178.8 +/2016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
AID1333536Toxicity in Syrian hamster infected with Leishmania tropica MHOM/MA/1988/LEM1314 promastigotes assessed as urea levels at 1 % administered tropically on footpad for 3 weeks starting at week 7 post infection measured 1 week post last dose (Rvb = 32.5 +/- 02016Journal of natural products, 09-23, Volume: 79, Issue:9
Topical Treatment of Leishmania tropica Infection Using (-)-α-Bisabolol Ointment in a Hamster Model: Effectiveness and Safety Assessment.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (222)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (1.35)18.7374
1990's6 (2.70)18.2507
2000's34 (15.32)29.6817
2010's138 (62.16)24.3611
2020's41 (18.47)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 74.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index74.28 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index124.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (74.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Trials11 (5.21%)5.53%
Trials3 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Reviews8 (3.79%)6.00%
Reviews1 (6.67%)6.00%
Case Studies0 (0.00%)4.05%
Case Studies2 (0.95%)4.05%
Case Studies1 (6.67%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
Other190 (90.05%)84.16%
Other10 (66.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]