hexaconazole

Description

Hexaconazole is a triazole fungicide that acts by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes. Its synthesis involves a multi-step process, starting with the reaction of 1,2,4-triazole with an appropriate alkyl halide followed by a series of reactions to introduce the desired substituents. Hexaconazole is highly effective against a broad spectrum of fungal diseases in a wide range of crops, including wheat, barley, rice, and fruit trees. Its importance lies in its ability to control fungal infections, protect crops from yield losses, and improve food security. Extensive research on hexaconazole focuses on its mode of action, efficacy against different fungal species, environmental fate, and potential risks to non-target organisms. Understanding these aspects is crucial for optimizing its application and minimizing its negative impacts.'

2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol : A member of the class of triazoles that is 1-hexyl-1H-1,2,4-triazole in which the hydrogens at position 2 of the hexyl chain are replaced by hydroxy and 2,4-dichlorophenyl groups. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

hexaconazole : A racemate comprising equimolar amounts of (R)- and (S)-hexaconazole. An agricultural fungicide introduced in the 1980s, it is not approved for use within the European Union. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]