Compounds > 4-nitrobenzylthioinosine
Page last updated: 2024-09-20

4-nitrobenzylthioinosine

Description

4-nitrobenzylthioinosine: inhibitor of nucleoside transport; acts on ENT1 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID65407
CHEMBL ID418509
CHEBI ID138859
SCHEMBL ID1321676
MeSH IDM0042132

Synonyms (58)

Synonym
MLS002153144
smr001230641
nitrobenzylthioinosine
nbmpr
9h-purine, 6-[[(4-nitrophenyl)methyl]thio]-9-beta-d-ribofuranosyl-
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-[6-[(4-nitrophenyl)methylsulfanyl]purin-9-yl]tetrahydrofuran-3,4-diol
s-(4-nitrobenzyl)-6-thioinosine, >=98%, solid
6-((4-nitrobenzyl)thio)-9-beta-d-ribofuranosylpurine
4-nitrobenzylthioinosine
einecs 253-753-4
6-(((4-nitrophenyl)methyl)thio)-9-beta-d-ribofuranosyl-9h-purine
nsc 296962
9h-purine, 6-(((4-nitrophenyl)methyl)thio)-9-beta-d-ribofuranosyl-
brn 1191080
6-(p-nitrobenzylthio)inosine
38048-32-7
nsc-296962
NCGC00162270-01
nbti
bdbm23617
s-(4-nitrobenzyl)-6-thioinosine
chembl418509 ,
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-(6-{[(4-nitrophenyl)methyl]sulfanyl}-9h-purin-9-yl)oxolane-3,4-diol
4-nitrobenzylmercaptopurine ribonucleoside
6-[(4-nitrobenzyl)sulfanyl]-9-(beta-d-ribofuranosyl)-9h-purine
CHEBI:138859
NCGC00162270-02
s6-nitrobenzyl mercaptopurine riboside
s6-(4-nitrobenzyl)mercaptopurine riboside
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-[6-[(4-nitrophenyl)methylsulfanyl]purin-9-yl]oxolane-3,4-diol
6-s-[(4-nitrophenyl)methyl]-6-thioinosine
C20439
SCHEMBL1321676
A823993
6-[(4-nitrobenzyl)thio]-9-beta-d-ribofuranosylpurine
HMS2234I17
unii-gv1l2dzm2z
gv1l2dzm2z ,
s-(4-nitrobenzyl)-6-thioinosine (nbti, nbmpr)
AKOS015912710
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-(6-((4-nitrobenzyl)thio)-9h-purin-9-yl)tetrahydrofuran-3,4-diol ,
mfcd00005745
DTXSID2040947
DYCJFJRCWPVDHY-LSCFUAHRSA-N
AS-74652
CS-W011652
6-((4-nitrobenzyl)thio)-9-.beta.-d-ribofuranosylpurine
6-((4-nitrobenzyl)thio)inosine
inosine, 6-s-((4-nitrophenyl)methyl)-6-thio-
s-(p-nitrobenzyl)-6-mercapto-9-.beta.-d-ribofuranosylpurine
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-(6-(4-nitrobenzylthio)-9h-purin-9-yl)tetrahydrofuran-3,4-diol
NBM ,
6-{[(4-nitrophenyl)methyl]sulfanyl}-9-beta-d-ribofuranosyl-9h-purine
NCGC00162270-05
s-4-nitrophenylmethyl-6-thioinosine
s-(4-nitrobenzyl)-6-thioinosine (nbmpr)
HY-W010936
Z2091980692

Drug Classes (1)

ClassDescription
purine nucleoside
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (13)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Beta-lactamaseEscherichia coli K-12Potency3.98110.044717.8581100.0000AID485294
thioredoxin reductaseRattus norvegicus (Norway rat)Potency33.58750.100020.879379.4328AID588453
ATAD5 protein, partialHomo sapiens (human)Potency0.02060.004110.890331.5287AID493107
GLS proteinHomo sapiens (human)Potency5.62340.35487.935539.8107AID624146
TDP1 proteinHomo sapiens (human)Potency14.67770.000811.382244.6684AID686978; AID686979
67.9K proteinVaccinia virusPotency11.22020.00018.4406100.0000AID720579
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency50.11870.354828.065989.1251AID504847
gemininHomo sapiens (human)Potency7.30780.004611.374133.4983AID624296
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency17.05640.060110.745337.9330AID485367; AID485368
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Multidrug resistance-associated protein 4Homo sapiens (human)IC50 (µMol)75.00000.20005.677410.0000AID678791
Equilibrative nucleoside transporter 1Homo sapiens (human)IC50 (µMol)0.00430.00013.688363.0000AID1745859; AID1912447; AID255288; AID296876; AID330912
Equilibrative nucleoside transporter 1Homo sapiens (human)Ki0.00060.00040.10381.1000AID146819; AID1798344; AID219062; AID296876; AID309988; AID330913; AID370699; AID392456
Solute carrier family 28 member 3Homo sapiens (human)Ki88.05002.10002.75003.4000AID370698
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Adenosine kinaseToxoplasma gondiiKm1.10001.10001.96672.4000AID33981
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (42)

Processvia Protein(s)Taxonomy
prostaglandin secretionMultidrug resistance-associated protein 4Homo sapiens (human)
cilium assemblyMultidrug resistance-associated protein 4Homo sapiens (human)
platelet degranulationMultidrug resistance-associated protein 4Homo sapiens (human)
xenobiotic metabolic processMultidrug resistance-associated protein 4Homo sapiens (human)
xenobiotic transmembrane transportMultidrug resistance-associated protein 4Homo sapiens (human)
bile acid and bile salt transportMultidrug resistance-associated protein 4Homo sapiens (human)
prostaglandin transportMultidrug resistance-associated protein 4Homo sapiens (human)
urate transportMultidrug resistance-associated protein 4Homo sapiens (human)
glutathione transmembrane transportMultidrug resistance-associated protein 4Homo sapiens (human)
transmembrane transportMultidrug resistance-associated protein 4Homo sapiens (human)
cAMP transportMultidrug resistance-associated protein 4Homo sapiens (human)
leukotriene transportMultidrug resistance-associated protein 4Homo sapiens (human)
monoatomic anion transmembrane transportMultidrug resistance-associated protein 4Homo sapiens (human)
export across plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
transport across blood-brain barrierMultidrug resistance-associated protein 4Homo sapiens (human)
guanine nucleotide transmembrane transportMultidrug resistance-associated protein 4Homo sapiens (human)
neurotransmitter uptakeEquilibrative nucleoside transporter 1Homo sapiens (human)
nucleobase-containing compound metabolic processEquilibrative nucleoside transporter 1Homo sapiens (human)
xenobiotic metabolic processEquilibrative nucleoside transporter 1Homo sapiens (human)
neurotransmitter transportEquilibrative nucleoside transporter 1Homo sapiens (human)
xenobiotic transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
lactationEquilibrative nucleoside transporter 1Homo sapiens (human)
nucleobase transportEquilibrative nucleoside transporter 1Homo sapiens (human)
adenine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
nucleoside transportEquilibrative nucleoside transporter 1Homo sapiens (human)
purine nucleoside transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
cytidine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
uridine transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
adenosine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
inosine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
hypoxanthine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
thymine transportEquilibrative nucleoside transporter 1Homo sapiens (human)
excitatory postsynaptic potentialEquilibrative nucleoside transporter 1Homo sapiens (human)
cellular response to glucose stimulusEquilibrative nucleoside transporter 1Homo sapiens (human)
cellular response to hypoxiaEquilibrative nucleoside transporter 1Homo sapiens (human)
pyrimidine-containing compound transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
transport across blood-brain barrierEquilibrative nucleoside transporter 1Homo sapiens (human)
nucleoside transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
guanine transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
uracil transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
pyrimidine nucleobase transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
purine nucleobase transmembrane transportEquilibrative nucleoside transporter 1Homo sapiens (human)
xenobiotic metabolic processSolute carrier family 28 member 3Homo sapiens (human)
xenobiotic transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
pyrimidine nucleobase transportSolute carrier family 28 member 3Homo sapiens (human)
uridine transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
sodium ion transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
pyrimidine-containing compound transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
nucleoside transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
purine nucleobase transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
pyrimidine nucleoside transportSolute carrier family 28 member 3Homo sapiens (human)
purine nucleoside transmembrane transportSolute carrier family 28 member 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (29)

Processvia Protein(s)Taxonomy
guanine nucleotide transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
protein bindingMultidrug resistance-associated protein 4Homo sapiens (human)
ATP bindingMultidrug resistance-associated protein 4Homo sapiens (human)
ABC-type xenobiotic transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
prostaglandin transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
urate transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
purine nucleotide transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
ABC-type glutathione S-conjugate transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
ABC-type bile acid transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
efflux transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
15-hydroxyprostaglandin dehydrogenase (NAD+) activityMultidrug resistance-associated protein 4Homo sapiens (human)
ATP hydrolysis activityMultidrug resistance-associated protein 4Homo sapiens (human)
glutathione transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
ATPase-coupled transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
xenobiotic transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
ATPase-coupled inorganic anion transmembrane transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
ABC-type transporter activityMultidrug resistance-associated protein 4Homo sapiens (human)
neurotransmitter transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
nucleoside transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
adenine transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
guanine transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
uracil transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
purine nucleoside transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
cytidine transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
uridine transmembrane transporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
pyrimidine- and adenosine-specific:sodium symporter activityEquilibrative nucleoside transporter 1Homo sapiens (human)
purine nucleobase transmembrane transporter activitySolute carrier family 28 member 3Homo sapiens (human)
nucleoside:sodium symporter activitySolute carrier family 28 member 3Homo sapiens (human)
protein bindingSolute carrier family 28 member 3Homo sapiens (human)
uridine transmembrane transporter activitySolute carrier family 28 member 3Homo sapiens (human)
purine-specific nucleoside:sodium symporter activitySolute carrier family 28 member 3Homo sapiens (human)
pyrimidine- and adenosine-specific:sodium symporter activitySolute carrier family 28 member 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (12)

Processvia Protein(s)Taxonomy
nucleolusMultidrug resistance-associated protein 4Homo sapiens (human)
Golgi apparatusMultidrug resistance-associated protein 4Homo sapiens (human)
plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
membraneMultidrug resistance-associated protein 4Homo sapiens (human)
basolateral plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
apical plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
platelet dense granule membraneMultidrug resistance-associated protein 4Homo sapiens (human)
external side of apical plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
plasma membraneMultidrug resistance-associated protein 4Homo sapiens (human)
plasma membraneEquilibrative nucleoside transporter 1Homo sapiens (human)
membraneEquilibrative nucleoside transporter 1Homo sapiens (human)
basolateral plasma membraneEquilibrative nucleoside transporter 1Homo sapiens (human)
apical plasma membraneEquilibrative nucleoside transporter 1Homo sapiens (human)
presynapseEquilibrative nucleoside transporter 1Homo sapiens (human)
postsynapseEquilibrative nucleoside transporter 1Homo sapiens (human)
plasma membraneEquilibrative nucleoside transporter 1Homo sapiens (human)
endoplasmic reticulum membraneSolute carrier family 28 member 3Homo sapiens (human)
plasma membraneSolute carrier family 28 member 3Homo sapiens (human)
brush border membraneSolute carrier family 28 member 3Homo sapiens (human)
plasma membraneSolute carrier family 28 member 3Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (52)

Assay IDTitleYearJournalArticle
AID296876Inhibition of ENT1 in human K562 cells by flow cytometric assay2007Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors.
AID1660979Inhibition of Escherichia coli shiga toxin2020Journal of medicinal chemistry, 08-13, Volume: 63, Issue:15
Structure-Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin.
AID330912Binding affinity to ENT1 transporter2008Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.
AID370698Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counter2009Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3
Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors.
AID678791TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cells2003Molecular pharmacology, May, Volume: 63, Issue:5
Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.
AID330913Displacement of 5-(SAENTA)-X8-fluorescein from human ENT1 transporter in human K562 cells2008Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.
AID255288Percent inhibition against ADO transporter at 1 uM nonselective2005Journal of medicinal chemistry, Nov-03, Volume: 48, Issue:22
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
AID370699Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometry2009Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3
Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors.
AID521220Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay2007Nature chemical biology, May, Volume: 3, Issue:5
Chemical genetics reveals a complex functional ground state of neural stem cells.
AID309988Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometry2007Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24
Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors.
AID392456Inhibition of human ENT12009Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
CoMFA and CoMSIA 3D-QSAR studies on S(6)-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1).
AID524796Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID146819Binding affinity of compound towards Nucleoside transporter es-type by facile competitive binding flow cytometric assay using the human K562 chronic melogenous leukemia cell line2003Journal of medicinal chemistry, Feb-27, Volume: 46, Issue:5
Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter.
AID33981Binding affinity at Toxoplasma gondii adenosine kinase.2004Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8
Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.
AID1912447Inhibition of the equilibrative nucleoside transporter (ENT1, SLC29A1) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay (PubChem AID: 1745861)2019Scientific reports, 09-24, Volume: 9, Issue:1
Label-free detection of transporter activity via GPCR signalling in living cells: A case for SLC29A1, the equilibrative nucleoside transporter 1.
AID524791Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID433257Inhibition of ENT1-mediated 99mTc-HAra-C uptake in human MIAPaCa-2 cells2009Bioorganic & medicinal chemistry letters, Aug-15, Volume: 19, Issue:16
Synthesis of radiolabeled cytarabine conjugates.
AID219062Displacement of 5-(SAENTA)-X8-fluorescein from K562 cell nucleoside transporter2004Bioorganic & medicinal chemistry letters, May-03, Volume: 14, Issue:9
Novel halogenated nitrobenzylthioinosine analogs as es nucleoside transporter inhibitors.
AID296875Inhibition of ENT1 in human K562 cells at 10 uM by flow cytometric assay2007Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors.
AID1578773Antimalarial activity against multi drug-resistant Plasmodium falciparum K1 assessed as reduction in parasite growth [3H]Hypoxanthine incorporation assay2019Journal of medicinal chemistry, 09-26, Volume: 62, Issue:18
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
AID433256Inhibition of ENT1-mediated 99mTc-HAra-C uptake in human H441 cells2009Bioorganic & medicinal chemistry letters, Aug-15, Volume: 19, Issue:16
Synthesis of radiolabeled cytarabine conjugates.
AID433258Inhibition of ENT1-mediated 99mTc-HAra-C uptake in human PANC-1 cells2009Bioorganic & medicinal chemistry letters, Aug-15, Volume: 19, Issue:16
Synthesis of radiolabeled cytarabine conjugates.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID588378qHTS for Inhibitors of ATXN expression: Validation
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1798344Flow Cytometric Assay from Article 10.1021/jm070311l: \\Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors.\\2007Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (653)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990199 (30.47)18.7374
1990's243 (37.21)18.2507
2000's140 (21.44)29.6817
2010's56 (8.58)24.3611
2020's15 (2.30)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (0.30%)5.53%
Reviews10 (1.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other654 (98.20%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
dilazep[no description available]medium570benzoate ester;
diazepane;
diester;
methoxybenzenes		cardioprotective agent;
platelet aggregation inhibitor;
vasodilator agent
dipyridamole[no description available]medium1690piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
dipyridamole[no description available]medium1691piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
trequinsin[no description available]medium10pyridopyrimidine
l 660,711[no description available]medium10quinolines
cyclic gmp[no description available]medium303',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
sildenafil[no description available]medium10piperazines;
pyrazolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
zaprinast[no description available]medium30triazolopyrimidines
pyrimethamine[no description available]medium10aminopyrimidine;
monochlorobenzenes		antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
sulfadiazine[no description available]medium10pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
adenosine[no description available]medium3030adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
6-benzylthioinosine[no description available]medium30
8-hydroxy-2-(di-n-propylamino)tetralin[no description available]medium10phenols;
tertiary amino compound;
tetralins		serotonergic antagonist
1,3-dipropyl-8-cyclopentylxanthine[no description available]medium310oxopurineadenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
atenolol[no description available]medium30ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic
baclofen[no description available]medium20amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
diazepam[no description available]medium601,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
ici 118551[no description available]medium10indanes
imipramine[no description available]medium10dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
ketanserin[no description available]medium10aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
methoctramine[no description available]medium20aromatic ether;
tetramine		muscarinic antagonist
muscimol[no description available]medium10alkaloid;
isoxazoles;
primary amino compound		fungal metabolite;
GABA agonist;
oneirogen;
psychotropic drug
nipecotic acid[no description available]medium20beta-amino acid;
piperidinemonocarboxylic acid
pirenzepine[no description available]medium20pyridobenzodiazepineanti-ulcer drug;
antispasmodic drug;
muscarinic antagonist
prazosin[no description available]medium10aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
protriptyline[no description available]medium10carbotricyclic compoundantidepressant
pyrilamine[no description available]medium10aromatic ether;
ethylenediamine derivative		H1-receptor antagonist
yohimbine[no description available]medium20methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
hemicholinium 3[no description available]medium10
kainic acid[no description available]medium40dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
glutamic acid[no description available]medium80glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
butaclamol[no description available]medium20amino alcohol;
organic heteropentacyclic compound;
tertiary alcohol;
tertiary amino compound		dopaminergic antagonist
selfotel[no description available]medium10non-proteinogenic alpha-amino acid
mesulergine[no description available]medium10ergot alkaloid;
sulfamides		antiparkinson drug;
dopamine agonist;
serotonergic antagonist
alpha,beta-methyleneadenosine 5'-triphosphate[no description available]medium60nucleoside triphosphate analogue
n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine[no description available]medium20adenosines;
monocarboxylic acid amide;
organoiodine compound		adenosine A3 receptor agonist
zm 241385[no description available]medium40diamino-1,3,5-triazine
dizocilpine[no description available]medium20secondary amino compound;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
2'-deoxyadenosine 5'-o-(1-thiotriphosphate)[no description available]medium10
bemesetron[no description available]medium30
4-diphenylacetoxy-n-methylpiperidine methiodide[no description available]medium30iodide salt;
quaternary ammonium salt		cholinergic antagonist;
muscarinic antagonist
sch 23390[no description available]medium10benzazepine
naloxone[no description available]medium20morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
istradefylline[no description available]medium10oxopurine
isoalloxazine[no description available]medium20benzo[g]pteridine-2,4-dione
st 1535[no description available]medium10
clozapine[no description available]medium30benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
gamma-aminobutyric acid[no description available]medium20amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
acetamide[no description available]medium10acetamides;
carboximidic acid;
monocarboxylic acid amide;
N-acylammonia
quinacrine[no description available]medium10acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
catechol[no description available]medium20catecholsallelochemical;
genotoxin;
plant metabolite
taxifolin[no description available]medium203'-hydroxyflavanones;
4'-hydroxyflavanones;
dihydroflavonols;
pentahydroxyflavanone;
secondary alpha-hydroxy ketone
phosphonoacetic acid[no description available]medium40monocarboxylic acid;
phosphonic acids		antiviral agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
3,4-dihydroxyphenylacetic acid[no description available]medium20catechols;
dihydroxyphenylacetic acid		human metabolite
aminocaproic acid[no description available]medium10amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite
diacetyl[no description available]medium10alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite
hydroquinone[no description available]medium20benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
melatonin[no description available]medium20acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
n-acetylserotonin[no description available]medium10acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist
pyrazinamide[no description available]medium10monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
taurine[no description available]medium30amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
2-amino-5-phosphonovalerate[no description available]medium10non-proteinogenic alpha-amino acidNMDA receptor antagonist
alpha-methyl-4-carboxyphenylglycine[no description available]medium10
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid[no description available]medium10
1-hydroxy-3-amino-2-pyrrolidone[no description available]medium10
ibotenic acid[no description available]medium10non-proteinogenic alpha-amino acidneurotoxin
n(8)-bromoacetyl-n(1)-3'-(4-indolyloxy)-2'-hydroxypropyl-1,8-diamino-4-menthane[no description available]medium10
sk&f-38393[no description available]medium20benzazepine;
catechols;
secondary amino compound
vanilmandelic acid[no description available]medium102-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite
1,10-diaminodecane[no description available]medium20
1,3-diethyl-8-phenylxanthine[no description available]medium10
1,3-dipropyl-8-(4-sulfophenyl)xanthine[no description available]medium10
1,5-dihydroxyisoquinoline[no description available]medium10isoquinolinolEC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
pk 11195[no description available]medium30aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent
1-(2-trifluoromethylphenyl)imidazole[no description available]medium10imidazoles
1-aminobenzotriazole[no description available]medium20
1-methylimidazole[no description available]medium10imidazoles
edelfosine[no description available]medium10glycerophosphocholine
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one[no description available]medium20oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor
2,2'-dipyridyl[no description available]medium20bipyridinechelator;
ferroptosis inhibitor
2-hydroxysaclofen[no description available]medium10organochlorine compound
3,4-dichloroisocoumarin[no description available]medium20isocoumarins;
organochlorine compound		geroprotector;
serine protease inhibitor
phaclofen[no description available]medium10organophosphate oxoanion;
zwitterion
3-aminobenzamide[no description available]medium10benzamides;
substituted aniline		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
3-bromo-7-nitroindazole[no description available]medium10
enprofylline[no description available]medium10oxopurineanti-arrhythmia drug;
anti-asthmatic drug;
bronchodilator agent;
non-steroidal anti-inflammatory drug
3-nitropropionic acid[no description available]medium10C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin
4-amino-1,8-naphthalimide[no description available]medium20benzoisoquinoline;
dicarboximide
4-aminopyridine[no description available]medium10aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
homovanillic acid[no description available]medium20guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
4-hydroxybenzoic acid hydrazide[no description available]medium10carbohydrazide;
phenols
4-phenyl-3-furoxancarbonitrile[no description available]medium201,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
5,5-dimethyl-1-pyrroline-1-oxide[no description available]medium101-pyrroline nitronesneuroprotective agent;
spin trapping reagent
phenytoin[no description available]medium10imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
5,7-dichlorokynurenic acid[no description available]medium10quinolines
5-(n,n-hexamethylene)amiloride[no description available]medium20aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker
ethylisopropylamiloride[no description available]medium20aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker
5-fluoroindole-2-carboxylic acid[no description available]medium20indolyl carboxylic acid
hydroxyindoleacetic acid[no description available]medium10indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
phenanthridone[no description available]medium20lactam;
phenanthridines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
immunosuppressive agent;
mutagen
6-chloromelatonin[no description available]medium10acetamides
6-hydroxymelatonin[no description available]medium10acetamides;
tryptamines		metabolite;
mouse metabolite
6-methoxytryptoline[no description available]medium10
6-nitroso-1,2-benzopyrone[no description available]medium20
7-chlorokynurenic acid[no description available]medium10organochlorine compound;
quinolinemonocarboxylic acid		neuroprotective agent;
NMDA receptor antagonist
7-nitroindazole[no description available]medium10
8-(4-sulfophenyl)theophylline[no description available]medium100
8-cyclopentyl-1,3-dimethylxanthine[no description available]medium40oxopurine
8-phenyltheophylline[no description available]medium90
acetazolamide[no description available]medium10monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
acetohexamide[no description available]medium10acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
ag 127[no description available]medium20nitrophenol
rtki cpd[no description available]medium20aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector
tyrphostin a23[no description available]medium20catechols
tyrphostin 25[no description available]medium20benzenetriol
tyrphostin a1[no description available]medium10methoxybenzenesgeroprotector
1-aminoindan-1,5-dicarboxylic acid[no description available]medium10
albuterol[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
alpha-methyltyrosine methyl ester[no description available]medium10
altretamine[no description available]medium10triamino-1,3,5-triazine
amfonelic acid[no description available]medium10
amifostine anhydrous[no description available]medium10diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent
theophylline[no description available]medium250dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
amoxapine[no description available]medium20dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor
aniracetam[no description available]medium10N-acylpyrrolidine;
pyrrolidin-2-ones
2-amino-4-phosphonobutyric acid[no description available]medium10
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate[no description available]medium10alpha-amino acid
aurintricarboxylic acid[no description available]medium20monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist
azathioprine[no description available]medium20aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug
azelaic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		antibacterial agent;
antineoplastic agent;
dermatologic drug;
plant metabolite
bay-k-8644[no description available]medium20(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
benzamide[no description available]medium10benzamides
bepridil[no description available]medium10pyrrolidines;
tertiary amine		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
bml 190[no description available]medium20N-acylindole
brimonidine[no description available]medium20imidazoles;
quinoxaline derivative;
secondary amine		adrenergic agonist;
alpha-adrenergic agonist;
antihypertensive agent
bumetanide[no description available]medium10amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
caffeine[no description available]medium80purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
carbamazepine[no description available]medium10dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
carbetapentane[no description available]medium10benzenes
carisoprodol[no description available]medium10carbamate estermuscle relaxant
carmustine[no description available]medium10N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
cgs 12066[no description available]medium10N-arylpiperazine;
organofluorine compound;
pyrroloquinoxaline		serotonergic agonist
cgs 15943[no description available]medium40aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline		adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant
chlorambucil[no description available]medium20aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
chlormezanone[no description available]medium101,3-thiazine;
lactam;
monochlorobenzenes;
sulfone		antipsychotic agent;
anxiolytic drug;
muscle relaxant
chlorothiazide[no description available]medium10benzothiadiazineantihypertensive agent;
diuretic
chlorpropamide[no description available]medium10monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
chlorzoxazone[no description available]medium101,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound		muscle relaxant;
sedative
cilostamide[no description available]medium20quinolines
cilostazol[no description available]medium30lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
cimetidine[no description available]medium30aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
cinoxacin[no description available]medium20cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent
ciprofibrate[no description available]medium10cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
clofibrate[no description available]medium10aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
clotrimazole[no description available]medium30conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
cx546[no description available]medium10
cyclothiazide[no description available]medium10benzothiadiazineantihypertensive agent;
diuretic
dephostatin[no description available]medium10
nonivamide[no description available]medium10capsaicinoid;
phenols		lachrymator
r 59022[no description available]medium10diarylmethane
diazoxide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
diphenyleneiodonium[no description available]medium10organic cation
disopyramide[no description available]medium10monocarboxylic acid amide;
pyridines;
tertiary amino compound		anti-arrhythmia drug
disulfiram[no description available]medium20organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
2-amino-7-phosphonoheptanoic acid[no description available]medium10
thiorphan[no description available]medium10N-acyl-amino acid
2,3-dimethoxy-1,4-naphthoquinone[no description available]medium201,4-naphthoquinones
domperidone[no description available]medium20benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
droperidol[no description available]medium20aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
ebselen[no description available]medium20benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger
ellipticine[no description available]medium20indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite
emodin[no description available]medium20trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor
ethosuximide[no description available]medium10dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker
etodolac[no description available]medium20monocarboxylic acid;
organic heterotricyclic compound		antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
felbamate[no description available]medium10carbamate esteranticonvulsant;
neuroprotective agent
felodipine[no description available]medium20dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
fenofibrate[no description available]medium20aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
flumazenil[no description available]medium30ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
fluorouracil[no description available]medium50nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
fluspirilene[no description available]medium20diarylmethane
flutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent
formoterol fumarate[no description available]medium20formamides;
phenols;
phenylethanolamines;
secondary alcohol;
secondary amino compound
fpl 64176[no description available]medium20carboxylic ester;
pyrroles		calcium channel agonist
furafylline[no description available]medium10oxopurine
furosemide[no description available]medium40chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
fusaric acid[no description available]medium10aromatic carboxylic acid;
pyridines
gabapentin[no description available]medium10gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
4-amino-5-hexynoic acid[no description available]medium10
glipizide[no description available]medium10aromatic amide;
monocarboxylic acid amide;
N-sulfonylurea;
pyrazines		EC 2.7.1.33 (pantothenate kinase) inhibitor;
hypoglycemic agent;
insulin secretagogue
glyburide[no description available]medium20monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
1-(5-isoquinolinesulfonyl)piperazine[no description available]medium10isoquinolines
haloperidol[no description available]medium20aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
hemicholinium 3[no description available]medium10morpholines
4-fluorohexahydrosiladifenidol[no description available]medium10
hydrochlorothiazide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
hydroxyurea[no description available]medium30one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
ibudilast[no description available]medium10pyrazolopyridine
ibuprofen[no description available]medium10monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
ic 261[no description available]medium20indoles
ifenprodil[no description available]medium10piperidines
indirubin-3'-monoxime[no description available]medium20
indomethacin[no description available]medium70aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
iodoacetamide[no description available]medium10
1-methyl-3-isobutylxanthine[no description available]medium503-isobutyl-1-methylxanthine
4-piperidinecarboxylic acid[no description available]medium20
4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline[no description available]medium10
jl 18[no description available]medium20
nsc 664704[no description available]medium20indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector
ketoconazole[no description available]medium20dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
ketoprofen[no description available]medium20benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
kynurenic acid[no description available]medium10monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
2-amino-3-phosphonopropionic acid[no description available]medium10alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist
lamotrigine[no description available]medium101,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic
lansoprazole[no description available]medium20benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
beta-lapachone[no description available]medium20benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite
leflunomide[no description available]medium20(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor
linopirdine[no description available]medium20indoles
loratadine[no description available]medium20benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist
loxoprofen[no description available]medium10cyclopentanones;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one[no description available]medium20chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
meclofenamate sodium anhydrous[no description available]medium10organic sodium salt
methiothepin[no description available]medium10aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist
nocodazole[no description available]medium20aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
3-Hydroxy-alpha-methyl-DL-tyrosine[no description available]medium10benzenes;
monocarboxylic acid
metolazone[no description available]medium20organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor
milrinone[no description available]medium20bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
minoxidil[no description available]medium10dialkylarylamine;
tertiary amino compound
mitotane[no description available]medium10diarylmethane
mitoxantrone[no description available]medium20dihydroxyanthraquinoneanalgesic;
antineoplastic agent
ml 7[no description available]medium20N-sulfonyldiazepane;
organoiodine compound		EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide[no description available]medium10naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide
n-bromoacetamide[no description available]medium10
ethylmaleimide[no description available]medium50maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
fg 7142[no description available]medium20beta-carbolines
fenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		membrane transport modulator
n 0840[no description available]medium20
nialamide[no description available]medium20organonitrogen compound;
organooxygen compound
niclosamide[no description available]medium20benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
nifedipine[no description available]medium20C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
niflumic acid[no description available]medium20aromatic carboxylic acid;
pyridines
nilutamide[no description available]medium10(trifluoromethyl)benzenes;
C-nitro compound;
imidazolidinone		androgen antagonist;
antineoplastic agent
nimesulide[no description available]medium10aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
nimodipine[no description available]medium302-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nitrendipine[no description available]medium20C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
masoprocol[no description available]medium20catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite
5-nitro-2-(3-phenylpropylamino)benzoic acid[no description available]medium20nitrobenzoic acid
ns 2028[no description available]medium10
ns 1619[no description available]medium20(trifluoromethyl)benzenes;
benzimidazoles;
phenols		potassium channel opener
o(6)-benzylguanine[no description available]medium10
ofloxacin[no description available]medium203-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline
olomoucine[no description available]medium202,6-diaminopurines;
ethanolamines		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
oxaprozin[no description available]medium201,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug
oxatomide[no description available]medium20benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist
oxiracetam[no description available]medium10organonitrogen compound;
organooxygen compound
oxolinic acid[no description available]medium10aromatic carboxylic acid;
organic heterotricyclic compound;
oxacycle;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antifungal agent;
antiinfective agent;
antimicrobial agent;
enzyme inhibitor
quinone[no description available]medium201,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite
fenclonine[no description available]medium10phenylalanine derivative
palmidrol[no description available]medium20endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent
1,7-dimethylxanthine[no description available]medium10dimethylxanthinecentral nervous system stimulant;
human blood serum metabolite;
human xenobiotic metabolite;
mouse metabolite
pd 98059[no description available]medium40aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
pentamidine[no description available]medium10aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
pentoxifylline[no description available]medium30oxopurine
perphenazine[no description available]medium20N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
phenyl biguanide[no description available]medium20guanidinescentral nervous system drug
phenylbutazone[no description available]medium20pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
phloretin[no description available]medium60dihydrochalconesantineoplastic agent;
plant metabolite
picotamide[no description available]medium20benzamides
pinacidil[no description available]medium20pyridines
pindolol[no description available]medium10indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
piperidine-4-sulfonic acid[no description available]medium10
piracetam[no description available]medium10organonitrogen compound;
organooxygen compound
pirenperone[no description available]medium20aromatic ketone
praziquantel[no description available]medium20isoquinolines
primidone[no description available]medium10pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
proglumide[no description available]medium10benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
propentofylline[no description available]medium60oxopurine
propofol[no description available]medium10phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
pf 5901[no description available]medium20quinolines
riluzole[no description available]medium20benzothiazoles
risperidone[no description available]medium201,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
ritanserin[no description available]medium20organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone[no description available]medium20methoxybenzenes
rolipram[no description available]medium10pyrrolidin-2-onesantidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
salmeterol xinafoate[no description available]medium10ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound
sb 202190[no description available]medium20imidazoles;
organofluorine compound;
phenols;
pyridines		apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sobuzoxane[no description available]medium10organic molecular entity
spiroxatrine[no description available]medium20imidazolidines
sq 22536[no description available]medium10nucleoside analogue;
oxolanes		EC 4.6.1.1 (adenylate cyclase) inhibitor
sulfaphenazole[no description available]medium10primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor
sulpiride[no description available]medium10benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
t0156[no description available]medium20naphthyridine derivative
1,4-bis(2-(3,5-dichloropyridyloxy))benzene[no description available]medium10
terfenadine[no description available]medium20diarylmethane
tetraisopropylpyrophosphamide[no description available]medium20phosphoramide
thalidomide[no description available]medium10phthalimides;
piperidones
theobromine[no description available]medium40dimethylxanthineadenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate[no description available]medium10trihydroxybenzoic acid
tolazamide[no description available]medium10N-sulfonylureahypoglycemic agent;
potassium channel blocker
tolbutamide[no description available]medium10N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid[no description available]medium10
ici 136,753[no description available]medium20pyrazolopyridine
triamterene[no description available]medium20pteridinesdiuretic;
sodium channel blocker
trimethoprim[no description available]medium20aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
tropicamide[no description available]medium10acetamides
tyrphostin a9[no description available]medium20alkylbenzenegeroprotector
vigabatrin[no description available]medium10gamma-amino acidanticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine[no description available]medium50
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole[no description available]medium20aromatic primary alcohol;
furans;
indazoles		antineoplastic agent;
apoptosis inducer;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
zardaverine[no description available]medium10organofluorine compound;
pyridazinone		anti-asthmatic drug;
bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
peripheral nervous system drug
cortisone acetate[no description available]medium10corticosteroid hormone
corticosterone[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
reserpine[no description available]medium20alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
procaine hydrochloride[no description available]medium10organic molecular entity
isoproterenol hydrochloride[no description available]medium20catechols
histamine dihydrochloride[no description available]medium10
carbachol[no description available]medium40ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
spironolactone[no description available]medium203-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
estrone[no description available]medium2017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
androsterone[no description available]medium2017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
promazine hydrochloride[no description available]medium20hydrochloride
pilocarpine hydrochloride[no description available]medium10hydrochloride
dimethylphenylpiperazinium iodide[no description available]medium20N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
pentylenetetrazole[no description available]medium30organic heterobicyclic compound;
organonitrogen heterocyclic compound
racepinephrine hydrochloride[no description available]medium20
(4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride[no description available]medium30
hexamethonium bromide[no description available]medium10
cystamine dihydrochloride[no description available]medium10
cantharidin[no description available]medium20cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide
tetraethylammonium chloride[no description available]medium20organic chloride salt;
quaternary ammonium salt		potassium channel blocker
aspartic acid[no description available]medium30aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
glutamine[no description available]medium20amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
vincristine[no description available]medium10acetate ester;
formamides;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
physostigmine[no description available]medium30carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
apomorphine[no description available]medium10aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
promethazine hydrochloride[no description available]medium20hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative
bromodeoxyuridine[no description available]medium20pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
levodopa[no description available]medium10amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
methoxamine hydrochloride[no description available]medium20dimethoxybenzene
papaverine hydrochloride[no description available]medium20
bretylium tosylate[no description available]medium20organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent
berlition[no description available]medium10dithiolanes;
heterocyclic fatty acid;
lipoic acid;
thia fatty acid		cofactor;
nutraceutical;
prosthetic group
methacholine chloride[no description available]medium10quaternary ammonium salt
androstenedione[no description available]medium2017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
colchicine[no description available]medium20alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
yohimbine hydrochloride[no description available]medium20
gallamine triethiodide[no description available]medium10
cycloheximide[no description available]medium40antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
cycloserine[no description available]medium104-amino-1,2-oxazolidin-3-one;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic;
zwitterion		antiinfective agent;
antimetabolite;
antitubercular agent;
metabolite;
NMDA receptor agonist
17-alpha-hydroxyprogesterone[no description available]medium2017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin
quinacrine monohydrochloride[no description available]medium20
chlorpromazine hydrochloride[no description available]medium20hydrochloride;
phenothiazines		anticoronaviral agent;
phenothiazine antipsychotic drug
cytarabine hydrochloride[no description available]medium10
tryptophan[no description available]medium30erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
lidocaine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug;
local anaesthetic
arginine[no description available]medium20arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
rotenone[no description available]medium30organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin
synephrine[no description available]medium10ethanolamines;
phenethylamine alkaloid;
phenols		alpha-adrenergic agonist;
plant metabolite
pyridostigmine bromide[no description available]medium10pyridinium salt
imipramine hydrochloride[no description available]medium20hydrochlorideantidepressant
neostigmine bromide[no description available]medium10bromide salt
edrophonium chloride[no description available]medium10chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
suramin sodium[no description available]medium20organic sodium saltangiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
pyrazolanthrone[no description available]medium20anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
methapyrilene hydrochloride[no description available]medium20hydrochlorideanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative
tetrracaine hydrochloride[no description available]medium10benzoate ester
chelidamic acid[no description available]medium10
2-chloroadenosine[no description available]medium160purine nucleoside
diphenhydramine hydrochloride[no description available]medium20hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
cysteamine hydrochloride[no description available]medium10
propantheline bromide[no description available]medium20xanthenes
hydralazine hydrochloride[no description available]medium10hydrochlorideantihypertensive agent;
vasodilator agent
ethamivan[no description available]medium10methoxybenzenes;
phenols
pargyline hydrochloride[no description available]medium20
aminophylline[no description available]medium10mixturebronchodilator agent;
cardiotonic drug
azacitidine[no description available]medium20N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
orphenadrine hydrochloride[no description available]medium20hydrochlorideantiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
betamethasone[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent
benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide[no description available]medium20
cyproterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin
bicuculline[no description available]medium20benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
podophyllotoxin[no description available]medium30furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
tetrahydrozoline hydrochloride[no description available]medium20hydrochloridenasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
dequalinium chloride[no description available]medium20organic chloride saltantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor
decamethonium dibromide[no description available]medium20
amitriptyline hydrochloride[no description available]medium20organic tricyclic compound
naphazoline hydrochloride[no description available]medium20organic molecular entity
doxylamine succinate[no description available]medium20organic molecular entity
carbamylhydrazine monohydrochloride[no description available]medium10organic molecular entity
formestane[no description available]medium2017-oxo steroid;
3-oxo-Delta(4) steroid;
enol;
hydroxy steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
debrisoquin sulfate[no description available]medium10organic sulfate salt
betaine hydrochloride[no description available]medium10
bethanechol chloride[no description available]medium10carbamate ester;
chloride salt;
quaternary ammonium salt		muscarinic agonist
acetylcysteine[no description available]medium20acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
Mecamylamine hydrochloride[no description available]medium20monoterpenoid
vinblastine[no description available]medium10
cyproheptadine hydrochloride (anhydrous)[no description available]medium20hydrochloride
5 alpha-androstane-3 alpha,17 beta-diol[no description available]medium10androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite
pimozide[no description available]medium20benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
azetidyl-2-carboxylic acid[no description available]medium10azetidine-2-carboxylic acid
muscarine[no description available]medium10
antazoline hydrochloride[no description available]medium20
doxifluridine[no description available]medium20organofluorine compound;
pyrimidine 5'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
prodrug
meclofenoxate hydrochloride[no description available]medium10
clonidine hydrochloride[no description available]medium10dichlorobenzene
beclomethasone[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug
buthionine sulfoximine[no description available]medium20diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
mexiletine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
cyclophosphamide[no description available]medium10hydratealkylating agent;
antineoplastic agent;
carcinogenic agent;
immunosuppressive agent
suxamethonium chloride[no description available]medium10chloride saltmuscle relaxant
cyclobenzaprine hydrochloride[no description available]medium20hydrochlorideantidepressant;
muscle relaxant
n-methylaspartate[no description available]medium10amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
3-deazaadenosine[no description available]medium30
metoclopramide hydrochloride[no description available]medium20
isoetharine mesylate[no description available]medium20
zalcitabine[no description available]medium60pyrimidine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
propionylpromazine hydrochloride[no description available]medium20
camptothecin[no description available]medium20delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
nsc-145,668[no description available]medium10hydrochlorideantimetabolite;
antineoplastic agent
clodronic acid[no description available]medium101,1-bis(phosphonic acid);
one-carbon compound;
organochlorine compound		antineoplastic agent;
bone density conservation agent
benserazide hydrochloride[no description available]medium20hydrochlorideantiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
pancuronium bromide[no description available]medium20bromide saltcholinergic antagonist;
muscle relaxant;
nicotinic antagonist
tetradecanoylphorbol acetate[no description available]medium80acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
danazol[no description available]medium2017beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector
metergoline[no description available]medium20carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist
lisuride[no description available]medium10monocarboxylic acid amideantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
serotonergic agonist
disopyramide phosphate[no description available]medium20organoammonium phosphate
bromocriptine[no description available]medium10indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist
ergocristine[no description available]medium10ergot alkaloid
triamcinolone[no description available]medium1011beta-hydroxy steroid;
16alpha-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
zidovudine[no description available]medium40azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
paclitaxel[no description available]medium20taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
buspirone hydrochloride[no description available]medium20hydrochlorideanxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
etoposide[no description available]medium40beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
propafenone hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
etazolate hydrochloride[no description available]medium20
ribavirin[no description available]medium1001-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
carbidopa[no description available]medium20catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
cephradine[no description available]medium10beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug
methyldopa[no description available]medium10L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
lonidamine[no description available]medium10dichlorobenzene;
indazoles;
monocarboxylic acid		antineoplastic agent;
antispermatogenic agent;
EC 2.7.1.1 (hexokinase) inhibitor;
geroprotector
dexibuprofen[no description available]medium10ibuprofennon-narcotic analgesic;
non-steroidal anti-inflammatory drug
quisqualic acid[no description available]medium10non-proteinogenic alpha-amino acid
pirfenidone[no description available]medium10pyridoneantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
flecainide acetate[no description available]medium20acetate saltanti-arrhythmia drug
nicardipine hydrochloride[no description available]medium20dihydropyridinegeroprotector
idarubicin[no description available]medium20anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
captopril[no description available]medium10alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
terazosin hydrochloride anhydrous[no description available]medium20
pergolide mesylate[no description available]medium20methanesulfonate saltantiparkinson drug;
dopamine agonist;
geroprotector
ranitidine hydrochloride[no description available]medium10
colforsin[no description available]medium110acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
cefaclor anhydrous[no description available]medium10cephalosporinantibacterial drug;
drug allergen
alo 2145[no description available]medium10hydrochloridealpha-adrenergic agonist;
antiglaucoma drug
enoximone[no description available]medium10aromatic ketone
atomoxetine[no description available]medium20aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
raloxifene hydrochloride[no description available]medium20hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
mifepristone[no description available]medium203-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive
quinpirole hydrochloride[no description available]medium10
imazodan[no description available]medium10
mibefradil dihydrochloride[no description available]medium20
aptiganel hydrochloride[no description available]medium20
phenelzine sulfate[no description available]medium20organic molecular entity
fluoxetine hydrochloride[no description available]medium20hydrochloride;
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
propranolol hydrochloride[no description available]medium20hydrochloride
bupropion hydrochloride[no description available]medium20aromatic ketone
diltiazem hydrochloride[no description available]medium10hydrochlorideantihypertensive agent;
calcium channel blocker;
vasodilator agent
trazodone hydrochloride[no description available]medium20hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
verapamil hydrochloride[no description available]medium20
doxazosin mesylate[no description available]medium20methanesulfonate saltgeroprotector
amantadine hydrochloride[no description available]medium20hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist
mevastatin[no description available]medium102-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite
chloroquine diphosphate[no description available]medium20
dobutamine hydrochloride[no description available]medium20hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
desipramine hydrochloride[no description available]medium20hydrochloridedrug allergen
dopamine hydrochloride[no description available]medium20catecholamine
proadifen hydrochloride[no description available]medium20
metrifudil[no description available]medium10
rutecarpine[no description available]medium20beta-carbolines
trihexyphenidyl hydrochloride[no description available]medium20aralkylamine
thioridazine hydrochloride[no description available]medium20hydrochloridefirst generation antipsychotic;
geroprotector
procainamide hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug
siquil[no description available]medium20hydrochlorideanticoronaviral agent
sotalol hydrochloride[no description available]medium10hydrochlorideanti-arrhythmia drug;
beta-adrenergic antagonist
oxymetazoline hydrochloride[no description available]medium20hydrochloridealpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
alprenolol hydrochloride[no description available]medium20hydrochloride
2-methoxyestradiol[no description available]medium2017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
fluphenazine hydrochloride[no description available]medium20phenothiazinesanticoronaviral agent
tryptamine monohydrochloride[no description available]medium20
clomipramine hydrochloride[no description available]medium20hydrochlorideanticoronaviral agent;
antidepressant;
serotonergic antagonist;
serotonergic drug
amiloride hydrochloride[no description available]medium20hydratediuretic;
sodium channel blocker
prazosin hydrochloride[no description available]medium20hydrochloride
mianserin hydrochloride[no description available]medium20hydrochloridegeroprotector
lomefloxacin hydrochloride[no description available]medium20hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent
fenspiride hydrochloride[no description available]medium20
nilverm[no description available]medium20organic molecular entity
sanguinarine chloride[no description available]medium20
ropinirole hydrochloride[no description available]medium20indoles
plasmenylserine[no description available]medium10O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5-aminovaleric acid hydrochloride[no description available]medium10
n-acetyltryptamine[no description available]medium20acetamides;
indoles
D-serine[no description available]medium10D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist
dihydroergotamine mesylate[no description available]medium20methanesulfonate saltnon-narcotic analgesic;
serotonergic agonist;
vasoconstrictor agent
ranolazine hydrochloride[no description available]medium20
loxapine succinate[no description available]medium20succinate saltgeroprotector
guanfacine hydrochloride[no description available]medium20acetamidesgeroprotector
pirenzepine dihydrochloride[no description available]medium10hydrochloride
labetalol hydrochloride[no description available]medium20salicylamides
acecainide hydrochloride[no description available]medium10
loperamide hydrochloride[no description available]medium20hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
maprotiline hydrochloride[no description available]medium20anthracenes
protoporphyrin ix, disodium salt[no description available]medium10
siguazodan[no description available]medium10pyridazinone
3-octadecanamido-2-ethoxypropylphosphocholine[no description available]medium10
chelerythrine chloride[no description available]medium20
tosyllysine chloromethyl ketone[no description available]medium20
5-(n-methyl-n-isobutyl)amiloride[no description available]medium20
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride[no description available]medium20hydrochlorideEC 2.7.11.13 (protein kinase C) inhibitor
amperozide hydrochloride[no description available]medium20hydrochlorideanxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist
pyrrolidine dithiocarbamic acid[no description available]medium20
agroclavine[no description available]medium10ergot alkaloid
s-methylisothiourea sulfate[no description available]medium10
p-Aminobenzamidine dihydrochloride[no description available]medium20organic molecular entity
benzamidine hydrochloride[no description available]medium10
ketorolac tromethamine[no description available]medium10organoammonium saltanalgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor
methionine sulfoximine[no description available]medium10L-alpha-amino acid zwitterion;
L-methionine derivative;
methionine sulfoximine;
non-proteinogenic L-alpha-amino acid		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
geroprotector
tretazicar[no description available]medium10
carbetapentane citrate[no description available]medium20carbonyl compound
phentolamine mesylate[no description available]medium20
mephentermine[no description available]medium202-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite
oxybutynin hydrochloride[no description available]medium20hydrochloride
nimustine[no description available]medium10hydrochlorideantineoplastic agent
cordium[no description available]medium10hydrate;
hydrochloride
L-2-aminoadipic acid[no description available]medium102-aminoadipic acidEscherichia coli metabolite;
human metabolite
prilocaine hydrochloride[no description available]medium20hydrochloridelocal anaesthetic
mor-14[no description available]medium10hydroxypiperidine;
piperidine alkaloid;
tertiary amino compound		anti-HIV agent;
cardioprotective agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
plant metabolite
brexanolone[no description available]medium203-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative
phenylisopropyladenosine[no description available]medium10aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent
hexamethonium chloride[no description available]medium10
6-(4-nitrobenzylthio)guanosine[no description available]medium210
3-aminopropylphosphonic acid[no description available]medium10phosphonic acids;
primary amino compound;
zwitterion		GABAB receptor agonist
5'-n-methylcarboxamideadenosine[no description available]medium10
3,7-dimethyl-1-propargylxanthine[no description available]medium40
zpck[no description available]medium20
n(6)-phenyladenosine[no description available]medium20purine nucleoside
tetrahydrodeoxycorticosterone[no description available]medium2021-hydroxy steroid
n-methyladenosine[no description available]medium10methyladenosine
mizoribine[no description available]medium20imidazolesanticoronaviral agent
1-amino-1,3-dicarboxycyclopentane[no description available]medium10
u 73122[no description available]medium10aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
alphaxalone[no description available]medium10corticosteroid hormone
s-nitrosoglutathione[no description available]medium10glutathione derivative;
nitrosothio compound		bronchodilator agent;
nitric oxide donor;
platelet aggregation inhibitor;
signalling molecule
cp-55,940[no description available]medium20
vanoxerine[no description available]medium20hydrochloridedopamine uptake inhibitor
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate[no description available]medium20beta-carbolines
u 69593[no description available]medium20monocarboxylic acid amide;
N-alkylpyrrolidine;
organic heterobicyclic compound;
oxaspiro compound		anti-inflammatory agent;
diuretic;
kappa-opioid receptor agonist
cv 3988[no description available]medium20
beta-carboline-3-carboxylic acid methyl ester[no description available]medium20beta-carbolines
methoctramine[no description available]medium20hydrochloridemuscarinic antagonist
hypotaurine[no description available]medium10aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite
dihydrokainate[no description available]medium10dicarboxylic acid
gabazine[no description available]medium10
cl 218872[no description available]medium10pyridazines;
ring assembly
betaxolol hydrochloride[no description available]medium20hydrochlorideantihypertensive agent;
beta-adrenergic antagonist
catechin[no description available]medium10hydrategeroprotector
1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine[no description available]medium20hydrobromideserotonergic antagonist
s-methylthiocitrulline[no description available]medium10imidothiocarbamic ester;
L-arginine derivative;
L-ornithine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
neuroprotective agent
dihydrocapsaicin[no description available]medium10capsaicinoid
ml 9[no description available]medium10
parthenolide[no description available]medium20germacranolide
3',4'-dichlorobenzamil[no description available]medium20guanidines;
pyrazines
1-(carboxymethylthio)tetradecane[no description available]medium10straight-chain fatty acid
2-iodomelatonin[no description available]medium10acetamides
arcaine, sulfate[no description available]medium10
gr 113808[no description available]medium20indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist
gallopamil hydrochloride[no description available]medium20
gamma-glutamylaminomethylsulfonic acid[no description available]medium10
buthionine sulfoximine[no description available]medium202-amino-4-(S-butylsulfonimidoyl)butanoic acidEC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
sb 204070a[no description available]medium20
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine[no description available]medium20(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist
l 655240[no description available]medium10methylindole
san 58035[no description available]medium20
nnc 711[no description available]medium10
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide[no description available]medium20diarylmethane
e 64[no description available]medium20dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor
azetidine-2,4-dicarboxylic acid[no description available]medium10
pre 084[no description available]medium20morpholines
methotrexate[no description available]medium70dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol[no description available]medium20
sr 2640[no description available]medium20quinolines
ici 204448[no description available]medium10
4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride[no description available]medium10
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide[no description available]medium20phenylindole
3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan[no description available]medium10
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine[no description available]medium40
l 741626[no description available]medium20piperidines
nisoxetine hydrochloride[no description available]medium20
ng-nitroarginine methyl ester[no description available]medium10hydrochlorideEC 1.14.13.39 (nitric oxide synthase) inhibitor
tilarginine acetate[no description available]medium10
alpha-guanidinoglutaric acid[no description available]medium10L-glutamic acid derivative
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomer[no description available]medium20
imidazole-4-acetic acid hydrochloride[no description available]medium10
nsc-141549[no description available]medium20
2-chloro-2-deoxyglucose[no description available]medium10
idazoxan hydrochloride[no description available]medium20
isoguvacine hydrochloride[no description available]medium10
8-methoxymethyl-3-isobutyl-1-methylxanthine[no description available]medium10oxopurine
cyc 202[no description available]medium202,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
Serotonin hydrochloride[no description available]medium10tryptamines
n-phthaloylglutamic acid[no description available]medium10L-glutamic acid derivative;
phthalimides
1,3-dipropyl-7-methylxanthine[no description available]medium10
ag 3-5[no description available]medium10C-nitro compound
n-n-propylnorapomorphine[no description available]medium10aporphine alkaloid
urapidil monohydrochloride[no description available]medium20
aminopterin[no description available]medium20dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen
azepexole, dihydrochloride[no description available]medium10
2,5-dimethoxy-4-iodoamphetamine hydrochloride[no description available]medium10
abt 980[no description available]medium20
sk&f 75670[no description available]medium20
esatenolol[no description available]medium10atenololbeta-adrenergic antagonist
nbi 27914[no description available]medium20dialkylarylamine;
tertiary amino compound
sb 216763[no description available]medium20indoles;
maleimides
(R)-atenolol[no description available]medium10atenolol
memantine hydrochloride[no description available]medium20hydrochlorideantidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
pefabloc[no description available]medium10
pongidae[no description available]medium20
succinylproline[no description available]medium10N-acyl-amino acid
sb 205384[no description available]medium20thienopyridine
hydrastine[no description available]medium20isoquinolinesmetabolite
gabaculine hydrochloride[no description available]medium10
etiron monohydrobromide[no description available]medium10
bmy 7378[no description available]medium10
vesamicol[no description available]medium10
cortisone[no description available]medium1011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
vincristine sulfate[no description available]medium20organic sulfate saltantineoplastic agent;
geroprotector
n-methylserotonin oxalate salt[no description available]medium10
nsc 95397[no description available]medium201,4-naphthoquinones
wortmannin[no description available]medium30acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
lithium chloride[no description available]medium10inorganic chloride;
lithium salt		antimanic drug;
geroprotector
canavanine[no description available]medium10amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		phytogenic insecticide;
plant metabolite
5-hydroxytryptophan[no description available]medium105-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
plant metabolite
ouabain[no description available]medium6011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
tosylphenylalanyl chloromethyl ketone[no description available]medium10alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor
monoiodotyrosine[no description available]medium10amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite
nitroarginine[no description available]medium10guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
willardiine[no description available]medium10amino acid zwitterion;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid
cortodoxone[no description available]medium20deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
amiodarone hydrochloride[no description available]medium20aromatic ketone
dicyclomine hydrochloride[no description available]medium20hydrochlorideantispasmodic drug;
muscarinic antagonist
metyrosine[no description available]medium10L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		antihypertensive agent;
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
nortriptyline hydrochloride[no description available]medium20organic tricyclic compoundgeroprotector
paromomycin sulfate[no description available]medium10
Dubinidine[no description available]medium10organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
cyclopamine[no description available]medium10piperidinesglioma-associated oncogene inhibitor
s-(4-azidophenacyl)glutathione[no description available]medium10peptide
hydroxylamine hydrochloride[no description available]medium20organic molecular entity
sb 228357[no description available]medium20indolyl carboxylic acid
3,5-dihydroxyphenylglycine[no description available]medium10amino acid zwitterion;
non-proteinogenic L-alpha-amino acid;
resorcinols
actinonin[no description available]medium20
vinpocetine[no description available]medium20alkaloidgeroprotector
dihydroergocristine monomesylate[no description available]medium20methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent
tretinoin[no description available]medium50retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
resveratrol[no description available]medium20resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
oleic acid[no description available]medium10octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
thapsigargin[no description available]medium20butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
brivudine[no description available]medium10
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol[no description available]medium20carbotetracyclic compound;
polyphenol		estrogen receptor agonist;
estrogen receptor antagonist;
geroprotector;
neuroprotective agent
2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid[no description available]medium10
adenosine-5'-(n-ethylcarboxamide)[no description available]medium180adenosines;
monocarboxylic acid amide		adenosine A1 receptor agonist;
adenosine A2A receptor agonist;
antineoplastic agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
L-cycloserine[no description available]medium104-amino-1,2-oxazolidin-3-oneanti-HIV agent;
anticonvulsant;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
1,4-dideoxy-1,4-imino-d-arabinitol[no description available]medium10
purvalanol a[no description available]medium10purvalanol
melphalan[no description available]medium20L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
isoliquiritigenin[no description available]medium20chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist
rauwolscine[no description available]medium10methyl 17-hydroxy-20xi-yohimban-16-carboxylate
gw9662[no description available]medium20benzamides
calmidazolium[no description available]medium20organic chloride saltapoptosis inducer;
calmodulin antagonist
tropisetron hydrochloride[no description available]medium20
Reactive blue 2[no description available]medium10anthraquinone
5,6-dichloro-1-ethyl-1,3-dihydro-2h-benzimidazol-2-one[no description available]medium10dichlorobenzene
quinidine sulfate[no description available]medium20
ipratropium bromide anhydrous[no description available]medium10
methamilane methiodide[no description available]medium10
pilocarpine nitrate[no description available]medium10
r 59949[no description available]medium20diarylmethane
n(6)-cyclopentyladenosine[no description available]medium100
methylatropine nitrate[no description available]medium10
sb 366791[no description available]medium20
ag-213[no description available]medium20
3,3',4,5'-tetrahydroxystilbene[no description available]medium20catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor
(S)-(-)-pindolol[no description available]medium10pindolol
levosulpiride[no description available]medium10sulpirideantidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
caffeic acid[no description available]medium10caffeic acidgeroprotector;
mouse metabolite
4-fluorophenyl-L-alanine[no description available]medium204-fluorophenylalanine;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid
urocanic acid[no description available]medium10urocanic acidhuman metabolite
cotinine[no description available]medium20N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite
cinnarizine[no description available]medium20diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
sulindac[no description available]medium20monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent
cysteine sulfinic acid[no description available]medium10organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite
d-ap7[no description available]medium10
(1R,2S)-tranylcypromine hydrochloride[no description available]medium20hydrochloride
tacrine hydrochloride[no description available]medium20
4-bromotetramisole, oxalate (1:1), salt(s)-isomer[no description available]medium20
3-hydroxybenzylhydrazine hydrochloride[no description available]medium20
1-(3-chlorophenyl)biguanide hydrochloride[no description available]medium20
4-chlorophenylalanine methyl ester, hydrochloride, (dl)-isomer[no description available]medium10
capsazepine[no description available]medium20benzazepine;
catechols;
monochlorobenzenes;
thioureas		capsaicin receptor antagonist
diphenyleneiodium chloride[no description available]medium20organic chloride saltEC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
G-protein-coupled receptor agonist
azetidine-2,4-dicarboxylic acid, (cis)-isomer[no description available]medium10
tamoxifen citrate[no description available]medium20citrate saltangiogenesis inhibitor;
anticoronaviral agent
pimagedine hydrochloride[no description available]medium10
Betaine Aldehyde Chloride[no description available]medium10quaternary ammonium salt
eskazine[no description available]medium20
monastrol[no description available]medium10enoate ester;
ethyl ester;
phenols;
racemate;
thioureas		antileishmanial agent;
antimitotic;
antineoplastic agent;
EC 3.5.1.5 (urease) inhibitor
u 0126[no description available]medium20aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
1-(4-hydroxybenzyl)imidazole-2-thiol[no description available]medium10
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamide[no description available]medium20
bp 897[no description available]medium20naphthalenecarboxamide
trequinsin hydrochloride[no description available]medium20
neboglamine[no description available]medium10
benzatropine methanesulfonate[no description available]medium20
sb 203186[no description available]medium10indolyl carboxylic acid
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea[no description available]medium201,2-thiazoles;
indoles;
ureas		receptor modulator;
serotonergic antagonist
gw 7647[no description available]medium20aryl sulfide;
monocarboxylic acid;
ureas		PPARalpha agonist
ro 41-0960[no description available]medium20
cgp 13501[no description available]medium10alkylbenzene
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide[no description available]medium20
brl 15572[no description available]medium20monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist
mrs 1523[no description available]medium20
or486[no description available]medium10
fg 9041[no description available]medium20quinoxaline derivative
iik7[no description available]medium10
sb 415286[no description available]medium20C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
dm 235[no description available]medium20
jhw 015[no description available]medium20indolecarboxamide
bw 723c86[no description available]medium20tryptamines
sc 560[no description available]medium20aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug
sc-19220[no description available]medium10aromatic ether
le 300[no description available]medium20indoles
ly 367265[no description available]medium20dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor
diclofenac sodium[no description available]medium10organic sodium salt
cgp 7930[no description available]medium20alkylbenzene
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole[no description available]medium20phenols;
pyrazoles		estrogen receptor agonist
sib 1757[no description available]medium20
sphingosine[no description available]medium10sphing-4-eninehuman metabolite;
mouse metabolite
apigenin[no description available]medium20trihydroxyflavoneantineoplastic agent;
metabolite
luteolin[no description available]medium103'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist
daphnetin[no description available]medium20hydroxycoumarin
genistein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
pulmicort[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen
timolol maleate[no description available]medium20maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
brompheniramine maleate[no description available]medium20maleate saltanti-allergic agent
chlorpheniramine maleate[no description available]medium20organic molecular entity
clemastine fumarate[no description available]medium20fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist
methylergonovine maleate[no description available]medium20ergoline alkaloidgeroprotector
astaxanthine[no description available]medium20carotenol;
carotenone		animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite
harman[no description available]medium20harmala alkaloid;
indole alkaloid fundamental parent;
indole alkaloid		anti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite
morin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent
myricetin[no description available]medium207-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite
daidzein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite
caffeic acid phenethyl ester[no description available]medium20alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent
rottlerin[no description available]medium20aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
flupenthixol[no description available]medium10flupenthixoldopaminergic antagonist
n-oleoyldopamine[no description available]medium20catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		TRPV1 agonist
pheniramine maleate[no description available]medium20organic molecular entity
tranilast[no description available]medium20amidobenzoic acid;
cinnamamides;
dimethoxybenzene;
secondary carboxamide		anti-allergic agent;
anti-asthmatic drug;
antineoplastic agent;
aryl hydrocarbon receptor agonist;
calcium channel blocker;
hepatoprotective agent;
nephroprotective agent
trimipramine maleate[no description available]medium20maleate saltantidepressant
isotretinoin[no description available]medium20retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent
xylometazoline hydrochloride[no description available]medium20
flunarizine hydrochloride[no description available]medium20diarylmethane
ketotifen fumarate[no description available]medium20organoammonium saltanti-asthmatic drug;
H1-receptor antagonist
cis-flupenthixol dihydrochloride[no description available]medium20hydrochloridegeroprotector
n-arachidonylglycine[no description available]medium20fatty amide;
N-acylglycine
n-oleoylethanolamine[no description available]medium20endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist
cyclosporine[no description available]medium20homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite
phenoxybenzamine hydrochloride[no description available]medium20organic molecular entity
phenylephrine hydrochloride[no description available]medium10hydrochloride
mepyramine maleate[no description available]medium20
brefeldin a[no description available]medium30macrolide antibioticPenicillium metabolite
fenretinide[no description available]medium20monocarboxylic acid amide;
retinoid		antineoplastic agent;
antioxidant
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid[no description available]medium20benzoic acids;
naphthalenes;
retinoid		antineoplastic agent;
retinoic acid receptor agonist;
teratogenic agent
l-2-(carboxypropyl)glycine[no description available]medium10
4-aminocrotonic acid[no description available]medium10
denopamine[no description available]medium10dimethoxybenzene
l 655,708[no description available]medium20
ro 41-1049[no description available]medium10
sb 200646a[no description available]medium20
seglitide[no description available]medium10
sib 1893[no description available]medium10
su 6656[no description available]medium20
tyrphostin ag 555[no description available]medium20
tyrphostin ag-494[no description available]medium10
tyrphostin b44[no description available]medium20
ag-490[no description available]medium20catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor
ag 112[no description available]medium20
ag 183[no description available]medium20
semaxinib[no description available]medium20olefinic compound;
oxindoles;
pyrroles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist
8-(3-chlorostyryl)caffeine[no description available]medium20monochlorobenzenes;
trimethylxanthine		adenosine A2A receptor antagonist;
EC 1.4.3.4 (monoamine oxidase) inhibitor
bay 11-7085[no description available]medium20benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor
molsidomine[no description available]medium10ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent
diamide[no description available]medium101,1'-azobis(N,N-dimethylformamide)
nomifensine maleate[no description available]medium20
nalbuphine hydrochloride[no description available]medium20hydrochloride
vinblastine sulfate[no description available]medium20
n-methylscopolamine bromide[no description available]medium10
dextromethorphan hydrobromide[no description available]medium20hydrate;
hydrobromide
naloxone hydrochloride[no description available]medium10hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
s-trans,trans-farnesylthiosalicylic acid[no description available]medium20sesquiterpenoid
sulindac sulfone[no description available]medium10monocarboxylic acid;
organofluorine compound;
sulfone		apoptosis inducer;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
naltrexone hydrochloride[no description available]medium20hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
guanabenz acetate[no description available]medium20dichlorobenzenegeroprotector
nylidrin hydrochloride[no description available]medium20alkylbenzene
triprolidine hydrochloride anhydrous[no description available]medium20hydrochlorideH1-receptor antagonist
famotidine[no description available]medium101,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
fenoterol[no description available]medium10hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
tiapridex[no description available]medium10benzamides
quipazine maleate[no description available]medium20
n-(2-aminoethyl)-4-chlorobenzamide hydrochloride[no description available]medium10
tulobuterol hydrochloride[no description available]medium20organic molecular entity
hp 029[no description available]medium20
n,n,n-trimethyl-1-(4-stilbenoxy)-2-propylammonium iodide[no description available]medium10
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one[no description available]medium20naphthalenes
nf023[no description available]medium10
nf 449[no description available]medium20
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine[no description available]medium20
gr 46611[no description available]medium10
diacetylmonoxime[no description available]medium10
homatropine hydrobromide, (endo-(+-)-isomer)[no description available]medium20
vancomycin hydrochloride[no description available]medium10
moxisylyte hydrochloride[no description available]medium10monoterpenoid
dizocilpine maleate[no description available]medium20maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
beta-aminopropionitrile fumarate[no description available]medium10
flupirtine[no description available]medium20
zimelidine hydrochloride[no description available]medium20
pregna-4,17-diene-3,16-dione, (17z)-isomer[no description available]medium20
su 4312[no description available]medium20
gw 1929[no description available]medium20benzophenones
protriptyline hydrochloride[no description available]medium20hydrochlorideantidepressant
n(4)-chloroacetylcytosine arabinoside[no description available]medium10
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamide[no description available]medium20
n-(4-amino-2-chlorophenyl)phthalimide[no description available]medium10
cb 34[no description available]medium10
b 43[no description available]medium20aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol[no description available]medium10aporphine alkaloid
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol[no description available]medium10aporphine alkaloid
3-(6-chloro-3-pyridazinyl)-3,8-diazabicyclo(3.2.1)octane[no description available]medium10
2-(3,3-diphenylpropylamino)acetamide[no description available]medium20diarylmethane
4-(2-(phenylsulfonylamino)ethylthio)-2,6-difluorophenoxyacetamide[no description available]medium10
gw2974[no description available]medium10pyridopyrimidine
l 162313[no description available]medium20
l-165041[no description available]medium10aromatic ketone
mrs 1754[no description available]medium10oxopurine
s-nitroso-n-acetylpenicillamine[no description available]medium20nitroso compound;
nitrosothio compound		nitric oxide donor;
vasodilator agent
pd 404182[no description available]medium10
sb 222200[no description available]medium20quinolines
dantrolene sodium[no description available]medium20
cr 2945[no description available]medium20
sb 218795[no description available]medium20quinolines
dihydroceramide[no description available]medium10N-acylsphinganine
epinephrine bitartrate[no description available]medium20
bicuculline methobromide[no description available]medium20
butylscopolammonium bromide[no description available]medium10
butaclamol hydrochloride[no description available]medium20
a 38503[no description available]medium20
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide[no description available]medium10
sk&f 89976-a[no description available]medium10
cv 1808[no description available]medium20purine nucleoside
fluvoxamine maleate[no description available]medium20(trifluoromethyl)benzenes
naloxone benzoylhydrazone[no description available]medium20
2-methyl-6-(phenylethynyl)pyridine hydrochloride[no description available]medium20hydrochlorideanxiolytic drug;
metabotropic glutamate receptor antagonist
amiprilose[no description available]medium10
(R)-fluoxetine hydrochloride[no description available]medium20hydrochlorideantidepressant;
serotonin uptake inhibitor
desmethylselegiline hydrochloride[no description available]medium10
3-morpholino-sydnonimine monohydrochloride[no description available]medium20
t 1032[no description available]medium20
qx-314 bromide[no description available]medium10
(S)-fluoxetine hydrochloride[no description available]medium20hydrochlorideantidepressant;
serotonin uptake inhibitor
sr 59230a[no description available]medium20
u 74389g[no description available]medium20
1-(2-methoxyphenyl)piperazine hydrochloride[no description available]medium20
y 27632, dihydrochloride, (4(r)-trans)-isomer[no description available]medium10
noscapine hydrochloride[no description available]medium20
a 77636[no description available]medium20hydrochlorideantiparkinson drug;
dopamine agonist
cgp 20712a[no description available]medium20
levodopa methyl ester hydrochloride[no description available]medium20
benalfocin hydrochloride[no description available]medium10
lu 19005[no description available]medium20
benoxathian hydrochloride[no description available]medium20
((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1h-inden-5-yl)oxy)acetic acid, (+)-isomer[no description available]medium20
n-cyclopropyl adenosine-5'-carboxamide[no description available]medium10
cefotaxime sodium[no description available]medium10organic sodium salt
calpain inhibitor iii[no description available]medium20
GR 127935 hydrochloride[no description available]medium20hydrochlorideserotonergic antagonist
mrs 1845[no description available]medium20
1-aminocyclopropane-1-carboxylic acid hydrochloride[no description available]medium20
alaproclate hydrochloride[no description available]medium20
ubenimex[no description available]medium20peptide
3-chloroalanine hydrochloride, (l-ala)-isomer[no description available]medium10
dsp 4 hydrochloride[no description available]medium20
calcimycin[no description available]medium50benzoxazole
(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride[no description available]medium20hydrochloridealpha-adrenergic antagonist
2-cyclooctyl-2-hydroxyethylamine hydrochloride[no description available]medium20
cirazoline monohydrochloride[no description available]medium20
adtn[no description available]medium20
apocodeine hydrochloride, (r)-isomer[no description available]medium20
Dihydro-beta-erythroidine hydrobromide[no description available]medium10indoles
lilly 78335[no description available]medium20
efaroxan hydrochloride[no description available]medium20
fenoldopam hydrobromide[no description available]medium20
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride[no description available]medium20hydrochloridedopamine uptake inhibitor
guvacine hydrochloride[no description available]medium10
7-hydroxy-2-n,n-dipropylaminotetralin hydrobromide[no description available]medium20
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (r)-isomer,[no description available]medium20organic molecular entity
1-(2-(4-(4-fluoro-benzoyl)-piperidin-1-yl)-ethyl)-3,3-dimethyl-1,2-dihydro-indol-2-one[no description available]medium20hydrochloridereceptor modulator;
serotonergic antagonist
4-iodoclonidine[no description available]medium20
4-methylpyrazole monohydrochloride[no description available]medium10
tele-methylhistamine[no description available]medium10
alpha-methyltyrosine methyl ester, monohydrochloride[no description available]medium20
octoclothepine maleate[no description available]medium20
2-(n-phenethyl-n-propyl)amino-5-hydroxytetralin hydrochloride[no description available]medium20
du 24565[no description available]medium20
2-methoxyidazoxan hydrochloride[no description available]medium20
ro 25-6981[no description available]medium20
sk&f 77434[no description available]medium20hydrobromidedopamine agonist;
prodrug
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea[no description available]medium20organic heterotetracyclic compound;
organonitrogen heterocyclic compound
demethylcantharidin[no description available]medium20
atropine sulfate[no description available]medium20
1-deoxynojirimycin hydrochloride[no description available]medium10
win 62577[no description available]medium20
quinine sulfate[no description available]medium20hydrate
quercetin[no description available]medium20
rv 538, (r-(r*,r*))-isomer[no description available]medium20
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (1s-cis)-isomer[no description available]medium20
valproate sodium[no description available]medium10organic sodium saltgeroprotector
u 63557a[no description available]medium10
taurocholic acid, monosodium salt[no description available]medium20bile salt
cefmetazole sodium[no description available]medium10organic sodium saltantimicrobial agent
fusidate sodium[no description available]medium20
cephapirin sodium[no description available]medium10cephalosporin;
organic sodium salt		antibacterial drug
sodium cephalothin[no description available]medium10organic sodium salt
cefazolin sodium[no description available]medium20organic sodium salt
5-hydroxydecanoic acid, monosodium salt[no description available]medium10
ro13-9904[no description available]medium10
phenytoin sodium[no description available]medium10
cr 1409[no description available]medium10
cortisol succinate, sodium salt[no description available]medium20organic molecular entity
piroxicam[no description available]medium30benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
lfm a13[no description available]medium10aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor
l 701324[no description available]medium10quinolines
hispidin[no description available]medium202-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite
minocycline hydrochloride[no description available]medium20
demeclocycline hydrochloride[no description available]medium20
acyclovir[no description available]medium202-aminopurines;
oxopurine		antimetabolite;
antiviral drug
sepiapterin[no description available]medium20sepiapterin
isoxanthopterin[no description available]medium10dihydroxypteridine
ganciclovir[no description available]medium302-aminopurines;
oxopurine		antiinfective agent;
antiviral drug
allopurinol[no description available]medium60nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
thiolactomycin[no description available]medium10
2,4-diaminohypoxanthine[no description available]medium10hydroxypyrimidine
quazinone[no description available]medium10
8-bromocyclic gmp, sodium salt[no description available]medium20organic sodium saltmuscle relaxant;
protein kinase G agonist
ag-879[no description available]medium20
lidoflazine[no description available]medium90diarylmethane
methylthioinosine[no description available]medium10purine ribonucleoside;
thiopurine
hyaluronoglucosaminidase[no description available]medium10purine nucleoside
n(6)-benzyladenosine[no description available]medium10
5-iodotubercidin[no description available]medium70organoiodine compound
2-hydroxy-5-nitrobenzylthioguanosine[no description available]medium50
phlorhizin[no description available]medium30aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		antioxidant;
plant metabolite
resacetophenone[no description available]medium10dihydroxyacetophenone;
resorcinols		plant metabolite
2,4,6-trihydroxyacetophenone[no description available]medium10aromatic ketone;
benzenetriol;
methyl ketone		MALDI matrix material;
plant metabolite
2,6-dihydroxyacetophenone[no description available]medium10aromatic ketone
trilobatin[no description available]medium10aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		anti-inflammatory agent;
antioxidant;
plant metabolite;
sweetening agent
cytarabine[no description available]medium220beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
cgp 52411[no description available]medium10phthalimidesgeroprotector;
tyrosine kinase inhibitor
aa 861[no description available]medium101,4-benzoquinones;
acetylenic compound;
primary alcohol		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor
bu 224[no description available]medium10quinolines
chloroquine[no description available]medium10aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
ml 9[no description available]medium10naphthalenes;
sulfonic acid derivative
pd 169316[no description available]medium10imidazoles
2-bromoergocryptine mesylate[no description available]medium10methanesulfonate saltantiparkinson drug
salmeterol xinafoate[no description available]medium10naphthoic acid
finasteride[no description available]medium103-oxo steroid;
aza-steroid;
delta-lactam		androgen antagonist;
antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
eliprodil[no description available]medium10monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary alcohol;
tertiary amino compound
sertraline hydrochloride[no description available]medium10hydrochlorideantidepressant;
serotonin uptake inhibitor
opipramol hydrochloride[no description available]medium10
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole[no description available]medium10ether;
imidazoles;
monomethoxybenzene		TRP channel blocker
u 78517f[no description available]medium10
mk 912[no description available]medium10
sk&f 86466[no description available]medium10benzazepine
w 7[no description available]medium10
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine[no description available]medium10
6-bromoindirubin-3'-oxime[no description available]medium10
h 89[no description available]medium20N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
phenylthiazolylthiourea[no description available]medium10
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)[no description available]medium10benzimidazoles
tg 003[no description available]medium10
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene[no description available]medium10C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector
quinine[no description available]medium10cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic
l 663536[no description available]medium10aryl sulfide;
indoles;
monocarboxylic acid;
monochlorobenzenes		antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
leukotriene antagonist
su 9516[no description available]medium10
ml 10302[no description available]medium10
ag 538[no description available]medium10
bw b70c[no description available]medium10aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
mg 624[no description available]medium10
5-(4-phenylbutoxy)psoralen[no description available]medium10aromatic ether;
benzenes;
psoralens		geroprotector;
immunosuppressive agent;
potassium channel blocker
bisoprolol, fumarate (1:1) salt[no description available]medium10
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride[no description available]medium10
ro 8-4304[no description available]medium10
sb 203186[no description available]medium10
2-hydroxyapomorphine, (r)-isomer[no description available]medium10
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide[no description available]medium10hydrobromidedopamine agonist;
prodrug
tubercidin[no description available]medium190antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
ribonucleoside		antimetabolite;
antineoplastic agent;
bacterial metabolite
nsc 65346[no description available]medium10nucleoside analogueprotein kinase inhibitor
coformycin[no description available]medium80coformycinsEC 3.5.4.4 (adenosine deaminase) inhibitor
adefovir[no description available]medium106-aminopurines;
ether;
phosphonic acids		antiviral drug;
DNA synthesis inhibitor;
drug metabolite;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent
adefovir dipivoxil[no description available]medium106-aminopurines;
carbonate ester;
ether;
organic phosphonate		antiviral drug;
DNA synthesis inhibitor;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent;
prodrug
psicofuranine[no description available]medium10psicose derivative;
purine nucleoside
9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine[no description available]medium10
9-(3-hydroxy-2-phosphonomethoxypropyl)-2,6-diaminopurine[no description available]medium10
angustmycin a[no description available]medium106-aminopurines
n(6)-methyl-2'-deoxyadenosine[no description available]medium10purine 2'-deoxyribonucleoside
pentostatin[no description available]medium120coformycinsantimetabolite;
antineoplastic agent;
Aspergillus metabolite;
bacterial metabolite;
EC 3.5.4.4 (adenosine deaminase) inhibitor
hypoxanthine[no description available]medium260nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
inosine[no description available]medium1240inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
forodesine[no description available]medium10dihydroxypyrrolidine;
pyrrolopyrimidine
immucillin g[no description available]medium10dihydroxypyrrolidine;
pyrrolopyrimidine
ulodesine[no description available]medium10
draflazine[no description available]medium130
alprazolam[no description available]medium10organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
bromazepam[no description available]medium10organic molecular entity
clonazepam[no description available]medium101,4-benzodiazepinone;
monochlorobenzenes		anticonvulsant;
anxiolytic drug;
GABA modulator
lorazepam[no description available]medium10benzodiazepine
oxazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anxiolytic drug;
environmental contaminant;
xenobiotic
prazepam[no description available]medium10benzodiazepine
chlordesmethyldiazepam[no description available]medium10benzodiazepine
2-chlorodiazepam[no description available]medium10
n-desmethylclobazam[no description available]medium10benzodiazepine
n-desmethylflunitrazepam[no description available]medium10
tamoxifen[no description available]medium30stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
lasalocid[no description available]medium10beta-hydroxy ketone;
monocarboxylic acid;
monohydroxybenzoic acid;
oxanes;
oxolanes;
polyether antibiotic;
secondary alcohol;
tertiary alcohol		bacterial metabolite;
coccidiostat;
ionophore
thioinosine[no description available]medium6402
4-aminopiperidine[no description available]medium11
novobiocin[no description available]medium10carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
mycophenolic acid[no description available]medium102-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
guanosine[no description available]medium310guanosines;
purines D-ribonucleoside		fundamental metabolite
darunavir[no description available]medium10carbamate ester;
furofuran;
sulfonamide		antiviral drug;
HIV protease inhibitor
trifluridine[no description available]medium10nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
EC 2.1.1.45 (thymidylate synthase) inhibitor
alovudine[no description available]medium20pyrimidine 2',3'-dideoxyribonucleoside
docetaxel anhydrous[no description available]medium10secondary alpha-hydroxy ketone;
tetracyclic diterpenoid		antimalarial;
antineoplastic agent;
photosensitizing agent
aminoimidazole carboxamide[no description available]medium30aminoimidazole;
monocarboxylic acid amide		mouse metabolite
aica ribonucleotide[no description available]medium101-(phosphoribosyl)imidazolecarboxamide;
aminoimidazole		cardiovascular drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
metformin[no description available]medium20guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
entecavir[no description available]medium102-aminopurines;
oxopurine;
primary alcohol;
secondary alcohol		antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
guanine[no description available]medium612-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
adenine[no description available]medium5406-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
9-(2-hydroxy-3-nonyl)adenine[no description available]medium390
2-chloro-n(6)cyclopentyladenosine[no description available]medium30
pilocarpine[no description available]medium10pilocarpineantiglaucoma drug
adenosine 5'-methylenediphosphate[no description available]medium90nucleoside diphosphate analogue
2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine[no description available]medium100adenosines;
dicarboxylic acid monoamide;
monocarboxylic acid		adenosine A2A receptor agonist;
anti-inflammatory agent
adenosine diphosphate[no description available]medium190adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
deoxycytidine[no description available]medium161pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
gemcitabine[no description available]medium81organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic
decitabine[no description available]medium102'-deoxyribonucleoside
uridine[no description available]medium1050uridinesdrug metabolite;
fundamental metabolite;
human metabolite
gliclazide[no description available]medium10
serine[no description available]medium20L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
carbon monoxide[no description available]medium10carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
cysteine[no description available]medium30cysteiniumfundamental metabolite
suramin[no description available]medium40naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
triazoles[no description available]medium701,2,3-triazole
arl-67156[no description available]medium10
cytidine[no description available]medium90cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
adenosine monophosphate[no description available]medium100adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
glycine[no description available]medium30alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
thiazolyl blue[no description available]medium20organic bromide saltcolorimetric reagent;
dye
sulindac sulfide[no description available]medium10aryl sulfide;
monocarboxylic acid;
organofluorine compound		antineoplastic agent;
apoptosis inducer;
non-steroidal anti-inflammatory drug
mefenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
thiazoles[no description available]medium201,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
oxotremorine[no description available]medium10N-alkylpyrrolidine
n-(1-methyl-2-phenylethyl)adenosine[no description available]medium30
krn 7000[no description available]medium10glycophytoceramide;
N-acyl-beta-D-galactosylphytosphingosine		allergen;
antigen;
antineoplastic agent;
epitope;
immunological adjuvant
proanthocyanidin a1[no description available]medium10flavonoid oligomer
procyanidin[no description available]medium10proanthocyanidin
flag peptide[no description available]medium10peptide
singlet oxygen[no description available]medium10chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
furfuryl alcohol[no description available]medium10furans;
primary alcohol		Maillard reaction product
4-chlorobenzoic acid[no description available]medium10monochlorobenzoic acidbacterial xenobiotic metabolite
methane[no description available]medium10alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2h-tetrazolium hydroxide[no description available]medium10
fluorescein-5-isothiocyanate[no description available]medium10fluorescein isothiocyanate
5'-s-(2-aminoethyl)-n(6)-(4-nitrobenzyl)-5'-thioadenosine[no description available]medium50
thymidine[no description available]medium430pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
7,8-dihydrobiopterin[no description available]medium107,8-dihydrobiopterin
sapropterin[no description available]medium105,6,7,8-tetrahydrobiopterincoenzyme;
cofactor;
diagnostic agent;
human metabolite
s-(4-nitrophenacyl)glutathione[no description available]medium10
adenosine kinase[no description available]medium160
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid[no description available]medium10
tannins[no description available]medium10
1,1-diphenyl-2-picrylhydrazyl[no description available]medium10
thiourea[no description available]medium10one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
amitriptyline[no description available]medium10carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
potassium chloride[no description available]medium30inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
guanosine monophosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite
verapamil[no description available]medium40aromatic ether;
nitrile;
polyether;
tertiary amino compound
tecadenoson[no description available]medium10
acadesine[no description available]medium201-ribosylimidazolecarboxamide;
aminoimidazole;
nucleoside analogue		antineoplastic agent;
platelet aggregation inhibitor
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone[no description available]medium10
idoxuridine[no description available]medium10organoiodine compound;
pyrimidine 2'-deoxyribonucleoside		antiviral drug;
DNA synthesis inhibitor
8-chloroadenosine-3',5'-cyclic monophosphorothioate[no description available]medium10
enkephalin, leucine[no description available]medium30pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
probenecid[no description available]medium20benzoic acids;
sulfonamide		uricosuric drug
morphine[no description available]medium20morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
deoxyglucose[no description available]medium50
formycins[no description available]medium210
formycin b[no description available]medium180formycin
quinazolines[no description available]medium60azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
pyrimidinones[no description available]medium10
2'-deoxyadenosine[no description available]medium20purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cytochrome c-t[no description available]medium10
leucine[no description available]medium20amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
niacinamide[no description available]medium20pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
p-aminohippuric acid[no description available]medium10N-acylglycineDaphnia magna metabolite
formycin[no description available]medium30formycinantineoplastic agent
cyclopentenyl cytosine[no description available]medium10
cytidine triphosphate[no description available]medium10cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
isoxazoles[no description available]medium20isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
preproenkephalin[no description available]medium10
casein kinase ii[no description available]medium20
methionine[no description available]medium20aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
purine[no description available]medium20purine
5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine[no description available]medium10cyanine dye;
indolium ion		fluorochrome
carbocyanines[no description available]medium10cyanine dye;
organic iodide salt		fluorochrome
acetaminophen[no description available]medium10acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
oligomycins[no description available]medium20
cladribine[no description available]medium50organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
uracil[no description available]medium40pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
thymine[no description available]medium20pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
meglumine[no description available]medium10hexosamine;
secondary amino compound
cytosine[no description available]medium10aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
mazindol[no description available]medium10organic molecular entity
pemetrexed[no description available]medium21N-acyl-L-glutamic acid;
pyrrolopyrimidine		antimetabolite;
antineoplastic agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
EC 2.1.1.45 (thymidylate synthase) inhibitor;
EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
citrulline[no description available]medium10amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
fluorine[no description available]medium10diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
phosphocreatine[no description available]medium10phosphagen;
phosphoamino acid		human metabolite;
mouse metabolite
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
pyruvic acid[no description available]medium102-oxo monocarboxylic acidcofactor;
fundamental metabolite
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
cyclopentane[no description available]medium20cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
pyrroles[no description available]medium10pyrrole;
secondary amine
dithiothreitol[no description available]medium501,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
1,2-dithiol-3-thione[no description available]medium101,2-dithiole
thiophenes[no description available]medium50mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
fludarabine[no description available]medium40purine nucleoside
vidarabine[no description available]medium60beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
bacterial metabolite;
nucleoside antibiotic
imatinib mesylate[no description available]medium10methanesulfonate saltanticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor
glycosides[no description available]medium10
papaverine[no description available]medium50benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
mrs 1220[no description available]medium10quinazolines
r 64719[no description available]medium30
glycogen[no description available]medium20
isoproterenol[no description available]medium20catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
nitrobenzylthioinosine 5'-monophosphate[no description available]medium70
ro 5-4864[no description available]medium20
4-chloromercuribenzenesulfonate[no description available]medium80arenesulfonic acid;
arylmercury compound
arachidonic acid[no description available]medium10icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
5'-methylthioadenosine[no description available]medium20thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
azides[no description available]medium30pseudohalide anionmitochondrial respiratory-chain inhibitor
deoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
showdomycin[no description available]medium10
enkephalin, ala(2)-mephe(4)-gly(5)-[no description available]medium10
4-azidosalicylic acid[no description available]medium10
salicylates[no description available]medium10monohydroxybenzoateplant metabolite
guanosine triphosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
uridine triphosphate[no description available]medium40pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
piperidines[no description available]medium10
piperine[no description available]medium10benzodioxoles;
N-acylpiperidine;
piperidine alkaloid;
tertiary carboxamide		food component;
human blood serum metabolite;
NF-kappaB inhibitor;
plant metabolite
hypochlorous acid[no description available]medium10chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
vitamin k semiquinone radical[no description available]medium10
raffinose[no description available]medium10raffinose family oligosaccharide;
trisaccharide		mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
gallopamil[no description available]medium10benzenes;
organic amino compound
adenosine diphosphate ribose[no description available]medium10ADP-sugarEscherichia coli metabolite;
mouse metabolite
isoleucine[no description available]medium10aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
dactinomycin[no description available]medium10actinomycinmutagen
glucose, (beta-d)-isomer[no description available]medium50D-glucopyranoseepitope;
mouse metabolite
octyl glucoside[no description available]medium50beta-D-glucosideplant metabolite
cytochalasin b[no description available]medium150cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor
staurosporine[no description available]medium10ammonium ion derivative
triiodothyronine[no description available]medium302-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
3-o-methylglucose[no description available]medium40D-aldohexose derivative
p-methoxy-n-methylphenethylamine[no description available]medium10aromatic ether;
secondary amino compound		metabolite
methylene blue[no description available]medium10organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
capsaicin[no description available]medium20capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
mioflazine[no description available]medium100
bucladesine[no description available]medium103',5'-cyclic purine nucleotide
uridine diphosphate glucuronic acid[no description available]medium10UDP-D-glucuronic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
4-nitrophenol[no description available]medium104-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
nitrophenols[no description available]medium10
iodoacetic acid[no description available]medium30haloacetic acid;
organoiodine compound		alkylating agent
dihydropyridines[no description available]medium30
5-(saenta-x8)fluorescein[no description available]medium20
erythrosine[no description available]medium20
bicuculline methiodide[no description available]medium10
transferrin[no description available]medium20
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid[no description available]medium10arenesulfonic acid;
azobenzenes;
methylpyridines;
monohydroxypyridine;
organic phosphate;
pyridinecarbaldehyde		purinergic receptor P2X antagonist
pyridoxal phosphate[no description available]medium10methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2-methylthio-atp[no description available]medium20
eicosapentaenoic acid[no description available]medium10icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical
promega[no description available]medium10
5'-adenylyl (beta,gamma-methylene)diphosphonate[no description available]medium20nucleoside triphosphate analogue
sucrose[no description available]medium30glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
substance p[no description available]medium10peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
tetrodotoxin[no description available]medium20azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium10isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
adenosine-3',5'-cyclic phosphorothioate[no description available]medium10nucleoside 3',5'-cyclic phosphorothioate
choline[no description available]medium10cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
6-methylpurine[no description available]medium10purinesEC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor
6-methylpurine 2'-deoxyriboside[no description available]medium10
ribose[no description available]medium20D-ribose;
ribopyranose
nad[no description available]medium10organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
n(6)-cyclohexyladenosine[no description available]medium120
cardiovascular agents[no description available]medium40
omega-n-methylarginine[no description available]medium10amino acid zwitterion;
arginine derivative;
guanidines;
L-arginine derivative;
non-proteinogenic L-alpha-amino acid
tbc-11251[no description available]medium10benzodioxoles
cocaine[no description available]medium10benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
8-chloro-cyclic adenosine monophosphate[no description available]medium10
8-chloroadenosine[no description available]medium10
8-bromo cyclic adenosine monophosphate[no description available]medium103',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
5'-amino-5'-deoxyadenosine[no description available]medium10
cytidylyl-3',5'-adenosine[no description available]medium10nucleoside analogue;
purines
pd 81723[no description available]medium10
bradykinin[no description available]medium10oligopeptidehuman blood serum metabolite;
vasodilator agent
phentolamine[no description available]medium10imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
bryostatin 1[no description available]medium10
raltitrexed[no description available]medium20N-acyl-amino acid
hexobendine[no description available]medium40trihydroxybenzoic acid
homocysteine[no description available]medium20amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
adamantane[no description available]medium10adamantanes;
polycyclic alkane
histamine[no description available]medium10aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
neurotensin[no description available]medium10peptide hormonehuman metabolite;
mitogen;
neurotransmitter;
vulnerary
sr 48692[no description available]medium10N-acyl-amino acid
chlorine[no description available]medium20halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
sr 142948a[no description available]medium10
sodium cyanide[no description available]medium10cyanide salt;
one-carbon compound;
sodium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor
dinoprost[no description available]medium10monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
cyclosporine[no description available]medium10
ng-nitroarginine methyl ester[no description available]medium20alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
penicillamine[no description available]medium10non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
ucn 1028 c[no description available]medium10
s-adenosylhomocysteine[no description available]medium20adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide		cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite
cyclopentanone[no description available]medium10cyclopentanonesMaillard reaction product
mannitol[no description available]medium20mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
procaine[no description available]medium10benzoate ester;
substituted aniline;
tertiary amino compound		central nervous system depressant;
drug allergen;
local anaesthetic;
peripheral nervous system drug
amiloride[no description available]medium10aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid[no description available]medium20
capecitabine[no description available]medium10carbamate ester;
cytidines;
organofluorine compound		antimetabolite;
antineoplastic agent;
prodrug
floxuridine[no description available]medium30nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
adenosine 5'-o-(3-thiotriphosphate)[no description available]medium10nucleoside triphosphate analogue
nebularine[no description available]medium10purine ribonucleoside;
purines D-ribonucleoside		fungal metabolite
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]medium20stilbenoid
concanavalin a[no description available]medium10
gramicidin a[no description available]medium10
fomepizole[no description available]medium10pyrazolesantidote;
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
protective agent
inosinic acid[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
phycoerythrin[no description available]medium10
vidarabine phosphate[no description available]medium10
5-fluoropyrimidine[no description available]medium10
stavudine[no description available]medium10dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
2-aminoisobutyric acid[no description available]medium102,2-dialkylglycine zwitterion;
2,2-dialkylglycine
guanylyl imidodiphosphate[no description available]medium10nucleoside triphosphate analogue
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
nystatin a1[no description available]medium10nystatins
arabinofuranosylcytosine triphosphate[no description available]medium50
dideoxyadenosine[no description available]medium20adenosines;
purine 2',3'-dideoxyribonucleoside		EC 3.5.4.4 (adenosine deaminase) inhibitor;
EC 4.6.1.1 (adenylate cyclase) inhibitor
2',5'-dideoxyadenosine[no description available]medium10deoxyribonucleoside
glucagon[no description available]medium10peptide hormone
zidovudine triphosphate[no description available]medium10
3'-azido-3'-deoxythymidine 5'phosphate[no description available]medium10
9-arabinofuranosylguanine[no description available]medium10beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
DNA synthesis inhibitor
denbufylline[no description available]medium10oxopurine
valinomycin[no description available]medium10cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
5'-(4-fluorosulfonylbenzoyl)adenosine[no description available]medium10
apyrase[no description available]medium10
5-fluorouridine[no description available]medium10organofluorine compound;
uridines		mutagen
rubidium[no description available]medium10alkali metal atom
prostaglandin a1[no description available]medium10prostaglandins A
potassium cyanide[no description available]medium10cyanide salt;
one-carbon compound;
potassium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
neurotoxin
1,4-dihydropyridine[no description available]medium20
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
beta-carboline-3-carboxylic acid ethyl ester[no description available]medium10beta-carbolines
flunitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes		anxiolytic drug;
GABAA receptor agonist;
sedative
8-azidoadenosine[no description available]medium10
p(1),p(5)-di(adenosine-5'-)pentaphosphate[no description available]medium10organophosphate oxoanion
xanthine[no description available]medium10xanthineSaccharomyces cerevisiae metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
beta-escin[no description available]medium10
azaserine[no description available]medium20carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
dimethylformamide[no description available]medium10formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent
methylnitronitrosoguanidine[no description available]medium10nitroso compoundalkylating agent
deoxyguanosine[no description available]medium10purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine[no description available]medium10purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
flurazepam[no description available]medium101,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
tertiary amino compound		anticonvulsant;
anxiolytic drug;
GABAA receptor agonist;
sedative
arginine[no description available]medium10
alpha-chymotrypsin[no description available]medium10
mopidamol[no description available]medium10dialkylarylamine;
tertiary amino compound
9-xylosyladenine[no description available]low00purine nucleoside
2-[6-(cyclohexylamino)-9-purinyl]-5-(hydroxymethyl)oxolane-3,4-diol[no description available]low00purine nucleoside
apnea[no description available]low00purine nucleoside
isoguanosine[no description available]low00purine nucleoside
2-aminoadenosine[no description available]low00purine nucleoside
8-bromoadenosine[no description available]low00purine nucleoside
n-allyladenosine[no description available]low00purine nucleoside
adenosine-5'-carboxylic acid[no description available]low00purine nucleoside
1,7-dimethylguanosine[no description available]low00purine nucleoside
8-methyladenosine[no description available]low00purine nucleoside
regadenoson[no description available]low00purine nucleoside
6-thioguanosine[no description available]low00purine nucleoside
5-(6-aminopurin-9-yl)-N-ethyl-3,4-dihydroxy-2-oxolanecarboxamide[no description available]low00purine nucleoside
nelarabine[no description available]low00beta-D-arabinoside;
monosaccharide derivative;
purine nucleoside		antineoplastic agent;
DNA synthesis inhibitor;
prodrug
(2R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol[no description available]low00purine nucleoside
n-((1s,trans)-2-hydroxycyclopentyl)adenosine[no description available]low00purine nucleoside
ver 155008[no description available]low00purine nucleoside
8-hydroxyguanosine[no description available]low00purine nucleoside
8-bromoguanosine[no description available]low00purine nucleoside
ConditionIndicatedRelationship StrengthStudiesTrials
Absence Seizure0low40
Absence Seizure Disorder0low10
Absence Seizures0low40
Acquired Immune Deficiency Syndrome0low30
Acquired Immuno-Deficiency Syndrome0low30
Acquired Immunodeficiency Syndrome0low30
Acute Disease0low40
Acute Lymphoid Leukemia0low20
Acute Myelogenous Leukemia0low60
Acute Myeloid Leukemia0low60
Acute Myeloid Leukemia with Maturation0low60
Acute Myeloid Leukemia without Maturation0low60
Acute Promyelocytic Leukemia0low70
Adenocarcinoma0low30
Adenocarcinoma, Basal Cell0low30
Adenocarcinoma, Granular Cell0low30
Adenocarcinoma, Oxyphilic0low30
Adenocarcinoma, Tubular0low30
Adenoma, Malignant0low30
Adverse Drug Event0low10
Adverse Drug Reaction0low10
African Sleeping Sickness0low10
African Trypanosomiasis0low10
Aging0low50
AIDS0low30
Akinetic Petit Mal0low10
ALL, Childhood0low20
Alloxan Diabetes0low30
AML M30low70
Anemia, Cooley's0low10
Anemia, Erythroblastic0low10
Anemia, Mediterranean0low10
Anesthesia0low10
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
ANLL0low60
Anoxemia0low60
Anoxia0low60
Anoxia, Brain0low10
Anoxia, Cerebral0low10
Anoxic Brain Damage0low10
Anoxic Encephalopathy0low10
Anterior Circulation Transient Ischemic Attack0low10
ATLL0low10
Atonic Absence Seizure0low40
Atonic Absence Seizures0low40
Atonic Seizure0low40
Atonic Seizures0low40
Atypical Mycobacterial Infection, Disseminated0low10
Atypical Mycobacterial Infection, Familial Disseminated0low10
Atypical Mycobacteriosis, Familial0low10
Atypical Mycobacteriosis, Familial Disseminated0low10
Atypical Mycobacterium Infections0low10
Aura0low20
Awakening Epilepsy0low20
B-Cell Chronic Lymphocytic Leukemia0low20
B-Cell Leukemia, Chronic0low20
B-Cell Malignancy, Low-Grade0low20
B-Lymphocytic Leukemia, Chronic0low20
Benign Neoplasms0low30
Benign Neoplasms, Brain0low20
Benign Psychomotor Epilepsy, Childhood0low20
beta Thalassemia0low10
beta-Thalassemia0low10
Bladder Cancer0medium11
Bladder Neoplasms0medium11
Bladder Tumors0medium11
Blood Pressure, High0low30
Body Weight0low20
Bone Cancer0low10
Bone Neoplasms0low10
Brain Anoxia0low10
Brain Cancer0low20
Brain Hypoxia0low10
Brain Ischemia0low40
Brain Metastases0low20
Brain Neoplasm, Primary0low20
Brain Neoplasms0low20
Brain Neoplasms, Benign0low20
Brain Neoplasms, Malignant0low20
Brain Neoplasms, Malignant, Primary0low20
Brain Neoplasms, Primary Malignant0low20
Brain Stem Ischemia, Transient0low10
Brain Stem Transient Ischemic Attack0low10
Brain TIA0low10
Brain Tumor, Primary0low20
Brain Tumor, Recurrent0low20
Brain Tumors0low20
Brainstem Ischemia, Transient0low10
Brainstem Transient Ischemic Attack0low10
Breast Cancer0low50
Breast Carcinoma0low50
Breast Neoplasms0low50
Breast Tumors0low50
Cancer0low30
Cancer of Bladder0medium11
Cancer of Bone0low10
Cancer of Brain0low20
Cancer of Breast0low50
Cancer of Colon0low50
Cancer of Lung0low10
Cancer of Ovary0low10
Cancer of Pancreas0low10
Cancer of the Bladder0medium11
Cancer of the Bone0low10
Cancer of the Brain0low20
Cancer of the Breast0low50
Cancer of the Colon0low50
Cancer of the Lung0low10
Cancer of the Ovary0low10
Cancer of the Pancreas0low10
Carcinoma 256, Walker0low20
Carcinoma, Cribriform0low30
Carcinoma, Ductal, Breast0low10
Carcinoma, Ehrlich Tumor0low90
Carcinoma, Granular Cell0low30
Carcinoma, Hepatocellular0low10
Carcinoma, Infiltrating Duct0low10
Carcinoma, Invasive Ductal, Breast0low10
Carcinoma, Lobular0low10
Carcinoma, Mammary Ductal0low10
Carcinoma, Non-Small Cell Lung0low10
Carcinoma, Non-Small-Cell Lung0low10
Carcinoma, Tubular0low30
Carcinosarcoma 256, Walker0low20
Cardiovascular Stroke0low40
Carotid Circulation Transient Ischemic Attack0low10
Cataleptic Attacks0low10
Cataplexy0low10
Cell Transformation, Neoplastic0low40
Cell Transformation, Viral0low20
Cerebral Anoxia0low10
Cerebral Hypoxia0low10
Cerebral Ischemia0low40
Cerebral Ischemia, Transient0low10
Chemical Dependence0low10
Childhood Absence Epilepsy0low10
Childhood Benign Psychomotor Epilepsy0low20
Choreoathetosis Self-Mutilation Hyperuricemia Syndrome0low10
Choreoathetosis Self-Mutilation Syndrome0low10
Choriocarcinoma0low30
Chronic Lymphocytic Leukemia0low20
Classic Galactosemia0low10
Clonic Seizure0low40
Clonic Seizures0low40
Colon Cancer0low50
Colon Neoplasms0low50
Colonic Cancer0low50
Colonic Neoplasms0low50
Colorectal Cancer0low10
Colorectal Carcinoma0low10
Colorectal Neoplasms0low10
Colorectal Tumors0low10
Complete HGPRT Deficiency Disease0low10
Complete HPRT Deficiency0low10
Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency0low10
Complex Partial Seizure0low40
Complex Partial Seizures0low40
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Contact Dermatitis0low10
Convulsion0low40
Convulsion, Non-Epileptic0low40
Convulsions0low40
Convulsions, Grand Mal0low10
Convulsive Seizure0low40
Convulsive Seizures0low40
Coronary Disease0low20
Coronary Heart Disease0low20
Crescendo Transient Ischemic Attacks0low10
Cryptogenic Tonic-Clonic Epilepsy0low10
Deficiency Disease, Complete HGPRT0low10
Deficiency Disease, Galactokinase0low10
Deficiency Disease, Galactose-1-Phosphate Uridyl-Transferase0low10
Deficiency Disease, Hypoxanthine-Phosphoribosyl-Transferase0low10
Deficiency Disease, UDP-Galactose-4-Epimerase0low10
Deficiency Disease, UDPglucose 4-Epimerase0low10
Deficiency of Glucose-6-Phosphate Dehydrogenase0low10
Deficiency of Guanine Phosphoribosyltransferase0low10
Deficiency of Hypoxanthine Phosphoribosyltransferase0low10
Deficiency, Glucosephosphate Dehydrogenase0low10
Deficiency, GPD0low10
Deficiency, Oxygen0low60
Delayed Effects, Prenatal Exposure0low10
Dermatitis Venenata0low10
Dermatitis, Contact0low10
Di Guglielmo Disease0low20
Di Guglielmo's Disease0low20
Diabetes Mellitus, Experimental0low30
Diabetes Mellitus, Gestational0low20
Diabetes, Gestational0low20
Diabetes, Pregnancy-Induced0low20
Diffuse Well-Differentiated Lymphocytic Lymphoma0low20
Disease Models, Animal0low90
Disrupted In B-Cell Malignancy0low20
Drug Abuse0low10
Drug Addiction0low10
Drug Dependence0low10
Drug Habituation0low10
Drug Side Effects0low10
Drug Toxicity0low10
Drug Use Disorders0low10
Drug Withdrawal Symptoms0low30
Drug-Related Side Effects and Adverse Reactions0low10
Dyskinesia Syndromes0low10
Eczema, Contact0low10
Ehrlich Ascites Tumor0low90
Electrocardiogram QT Prolonged0low10
Encephalopathy, Hypoxic0low10
Encephalopathy, Ischemic0low40
Epilepsy0low20
Epilepsy Juvenile Absence0low10
Epilepsy, Absence0low10
Epilepsy, Absence, Atypical0low10
Epilepsy, Benign Psychomotor, Childhood0low20
Epilepsy, Cryptogenic0low20
Epilepsy, Grand Mal0low10
Epilepsy, Lateral Temporal0low20
Epilepsy, Major0low10
Epilepsy, Minor0low10
Epilepsy, Petit Mal0low10
Epilepsy, Temporal Lobe0low20
Epilepsy, Tonic-Clonic0low10
Epilepsy, Tonic-Clonic, Cryptogenic0low10
Epilepsy, Tonic-Clonic, Familial0low10
Epilepsy, Tonic-Clonic, Symptomatic0low10
Epilepsy, Uncinate0low20
Epileptic Seizure0low40
Epileptic Seizures0low40
Epimerase Deficiency Galactosemia0low10
Erythremic Myelosis0low20
Erythroblastic Anemia0low10
Erythroblastic Leukemia, Acute0low20
Erythroleukemia0low20
Etat Marbre0low10
Experimental Diabetes Mellitus0low30
Experimental Hepatoma0low40
Experimental Hepatomas0low40
Experimental Leukemia0low40
Experimental Leukemias0low40
Experimental Liver Neoplasms0low40
Experimental Neoplasms0low30
Familial Tonic-Clonic Epilepsy0low10
Fasting Hypoglycemia0low10
Fetal Growth Restriction0low10
Fetal Growth Retardation0low10
Fever, Zika0low10
G6PD Deficiency0low10
Galactokinase Deficiency0low10
Galactokinase Deficiency Disease0low10
Galactose Epimerase Deficiency0low10
Galactose-1-Phosphate Uridyl-Transferase Deficiency Disease0low10
Galactose-1-Phosphate Uridyltransferase Deficiency0low10
Galactose-1-Phosphate Uridylyltransferase Deficiency0low10
Galactosemia0low10
Galactosemia 20low10
Galactosemia 30low10
Galactosemia III0low10
Galactosemia, Classic0low10
Galactosemias0low10
GALE Deficiency0low10
GALK Deficiency0low10
GALT Deficiency0low10
Gelineau Syndrome0low10
Gelineau's Syndrome0low10
Generalized Absence Seizure0low40
Generalized Absence Seizures0low40
Generalized Tonic-Clonic Seizures0low40
Genital Neoplasms, Male0low10
Germinoblastoma0low140
Gestational Diabetes0low20
Glial Cell Tumors0low30
Glioma0low30
Glucose 6 Phosphate Dehydrogenase Deficiency0low10
Glucose-6-Phosphate Dehydrogenase Deficiency0low10
Glucosephosphate Dehydrogenase Deficiencies0low10
Glucosephosphate Dehydrogenase Deficiency0low10
GPD Deficiency0low10
Grand Mal Seizure Disorder0low10
Granulocytic Leukemia0low30
Growth Retardation, Intrauterine0low10
Heart Attack0low40
Heart Disease, Ischemic0low110
Hemoglobin F Disease0low10
Hemoglobinopathies0low10
Hemolytic Anemia Due to G6PD Deficiency0low10
Hemorrhage, Subarachnoid0low10
Henneberg Syndrome0low10
Hepadnaviridae Infections0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Hepatoma, Experimental0low40
Hepatoma, Morris0low40
Hepatoma, Novikoff0low40
Hepatomas, Experimental0low40
Hereditary Galactokinase Deficiency0low10
HGPRT Deficiency0low10
HGPRT Deficiency Disease, Complete0low10
Hibernation, Myocardial0low80
HIV0low10
HTLV I Associated T Cell Leukemia Lymphoma0low10
HTLV-Associated Leukemia-Lymphoma0low10
HTLV-I-Associated T-Cell Leukemia-Lymphoma0low10
Human Mammary Carcinoma0low50
Human T Lymphotropic Virus Associated Leukemia Lymphoma0low10
Human T Lymphotropic Virus-Associated Leukemia-Lymphoma0low10
Human T-Cell Leukemia-Lymphoma0low10
Hyperoxia0low10
Hyperprolactinaemia0low10
Hyperprolactinemia0low10
Hypersensitivity, Contact0low10
Hypertension0low30
Hyperthyroid0low20
Hyperthyroidism0low20
Hypoglycemia0low10
Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency0low10
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency0low10
Hypoxanthine Phosphoribosyltransferase Deficiency0low10
Hypoxanthine-Phosphoribosyl-Transferase Deficiency Disease0low10
Hypoxemia0low60
Hypoxia0low60
Hypoxia, Brain0low10
Hypoxia, Cerebral0low10
Hypoxic Brain Damage0low10
Hypoxic Encephalopathy0low10
Immunodeficiency Syndrome, Acquired0low30
Immunologic Deficiency Syndrome, Acquired0low30
Inadequate Sleep0low30
Inappropriate Prolactin Secretion0low10
Inappropriate Prolactin Secretion Syndrome0low10
Infections, Atypical Mycobacterium0low10
Infections, Hepadnaviridae0low10
Infections, Plasmodium0low30
Inflammation0low10
Injury, Ischemia-Reperfusion0low20
Injury, Myocardial Reperfusion0low140
Injury, Reperfusion0low20
Innate Inflammatory Response0low10
Insufficient Sleep0low30
Insufficient Sleep Syndrome0low30
Intermittent Claudication0low10
Intracranial Neoplasms0low20
Intrauterine Growth Restriction0low10
Intrauterine Growth Retardation0low10
Invasive Ductal Carcinoma, Breast0low10
Invasiveness, Neoplasm0low20
Ischemia0low50
Ischemia-Reperfusion Injury0low20
Ischemia, Cerebral0low40
Ischemia, Myocardial0low110
Ischemic Attack, Transient0low10
Ischemic Encephalopathy0low40
Ischemic Heart Disease0low110
Itching0low10
Jacksonian Seizure0low40
Juvenile Absence Epilepsy0low10
Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome0low10
Juvenile Hyperuricemia Syndrome0low10
Kahler Disease0low10
Kidney Diseases0low10
Late Effects, Prenatal Exposure0low10
Left Ventricular Dysfunction0low10
Leiomyosarcoma0low10
Leiomyosarcoma, Epithelioid0low10
Leiomyosarcoma, Myxoid0low10
Leishmania Infection0low10
Leishmaniasis0low10
Lesch-Nyhan Disease0low10
Lesch-Nyhan Syndrome0low10
Leucocythaemia0low90
Leucocythemia0low90
Leukemia0low90
Leukemia L 12100low170
Leukemia L12100low170
Leukemia L51780low10
Leukemia Lymphoma, Adult T Cell0low10
Leukemia Lymphoma, T Cell, Acute, HTLV I Associated0low10
Leukemia Model, Animal0low40
Leukemia P3880low70
Leukemia-Lymphoma, Adult T-Cell0low10
Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated0low10
Leukemia, Acute Lymphoblastic0low20
Leukemia, Acute Myelogenous0low60
Leukemia, Acute Myeloid0low60
Leukemia, Acute Promyelocytic0low70
Leukemia, Adult T-Cell0low10
Leukemia, B Cell, Chronic0low20
Leukemia, B-Cell, Chronic0low20
Leukemia, Chronic Lymphatic0low20
Leukemia, Chronic Lymphocytic0low20
Leukemia, Chronic Lymphocytic, B-Cell0low20
Leukemia, Erythroblastic, Acute0low20
Leukemia, Experimental0low40
Leukemia, Granulocytic0low30
Leukemia, Lymphoblastic0low20
Leukemia, Lymphoblastic, Acute0low20
Leukemia, Lymphoblastic, Acute, L10low20
Leukemia, Lymphoblastic, Acute, L20low20
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive0low20
Leukemia, Lymphoblastic, Chronic0low20
Leukemia, Lymphocytic0low20
Leukemia, Lymphocytic, Acute0low20
Leukemia, Lymphocytic, Acute, L10low20
Leukemia, Lymphocytic, Acute, L20low20
Leukemia, Lymphocytic, Chronic0low20
Leukemia, Lymphocytic, Chronic, B Cell0low20
Leukemia, Lymphocytic, Chronic, B-Cell0low20
Leukemia, Lymphocytic, T Cell0low30
Leukemia, Lymphocytic, T-Cell0low30
Leukemia, Lymphoid0low20
Leukemia, Lymphoid, Acute0low20
Leukemia, Monocytic, Chronic0low30
Leukemia, Myeloblastic, Acute0low60
Leukemia, Myelocytic0low30
Leukemia, Myelocytic, Acute0low60
Leukemia, Myelogenous0low30
Leukemia, Myelogenous, Acute0low60
Leukemia, Myeloid0low30
Leukemia, Myeloid, Acute0low60
Leukemia, Myeloid, Acute, M10low60
Leukemia, Myeloid, Acute, M20low60
Leukemia, Myeloid, Acute, M30low70
Leukemia, Myeloid, Acute, M40low20
Leukemia, Myeloid, Acute, M60low20
Leukemia, Myeloid, Naegeli-Type0low20
Leukemia, Myelomonocytic, Acute0low20
Leukemia, Nonlymphoblastic, Acute0low60
Leukemia, Nonlymphocytic, Acute0low60
Leukemia, Progranulocytic0low70
Leukemia, Promyelocytic, Acute0low70
Leukemia, T-Cell0low30
Leukemias, Experimental0low40
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Neoplasms, Experimental0low40
Long QT Syndrome0low10
Lung Cancer0low10
Lung Neoplasms0low10
Lymphoblastic Leukemia0low20
Lymphoblastic Leukemia, Acute0low20
Lymphoblastic Leukemia, Acute, Adult0low20
Lymphoblastic Leukemia, Acute, Childhood0low20
Lymphoblastic Leukemia, Acute, L10low20
Lymphoblastic Leukemia, Acute, L20low20
Lymphoblastic Leukemia, Chronic0low20
Lymphoblastic Lymphoma0low20
Lymphocytic Leukemia0low20
Lymphocytic Leukemia, Acute0low20
Lymphocytic Leukemia, Chronic0low20
Lymphocytic Leukemia, Chronic, B Cell0low20
Lymphocytic Leukemia, Chronic, B-Cell0low20
Lymphocytic Leukemia, L10low20
Lymphocytic Leukemia, L20low20
Lymphocytic Leukemia, T-Cell0low30
Lymphocytic Lymphoma0low20
Lymphocytic Lymphoma, Diffuse, Well Differentiated0low20
Lymphocytic Lymphoma, Diffuse, Well-Differentiated0low20
Lymphocytic Lymphoma, Well Differentiated0low20
Lymphocytic Lymphoma, Well-Differentiated0low20
Lymphoid Leukemia0low20
Lymphoma0low140
Lymphoma L51780low10
Lymphoma, Lymphoblastic0low20
Lymphoma, Lymphocytic0low20
Lymphoma, Lymphocytic, Diffuse, Well Differentiated0low20
Lymphoma, Lymphocytic, Diffuse, Well-Differentiated0low20
Lymphoma, Lymphocytic, Well Differentiated0low20
Lymphoma, Lymphocytic, Well-Differentiated0low20
Lymphoma, Lymphoplasmacytoid, CLL0low20
Lymphoma, Malignant0low140
Lymphoma, Small Lymphocytic0low20
Lymphoma, Small Lymphocytic, Plasmacytoid0low20
Lymphoma, Small-Cell0low20
Lymphoplasmacytoid Lymphoma, CLL0low20
M3 ANLL0low70
Major Motor Seizure Disorder0low10
Malaria0low30
Malaria, Falciparum0low20
Malaria, Vivax0low10
Male Genital Neoplasms0low10
Malignancy0low30
Malignant Glioma0low30
Malignant Melanoma0low10
Malignant Neoplasm of Breast0low50
Malignant Neoplasms0low30
Malignant Neoplasms, Brain0low20
Malignant Primary Brain Neoplasms0low20
Malignant Primary Brain Tumors0low20
Malignant Tumor of Breast0low50
Malignant Tumor of Urinary Bladder0medium11
Mammary Cancer0low50
Mammary Carcinoma, Human0low50
Mammary Ductal Carcinoma0low10
Mammary Neoplasm, Human0low50
Mammary Neoplasms, Human0low50
Marsh Fever0low30
Mediterranean Anemia0low10
Melanoma0low10
Mesothelioma0low10
Metastase0low10
Metastases, Neoplasm0low10
Metastasis0low10
Metastasis, Neoplasm0low10
Microcytemia, beta Type0low10
Mixed Glioma0low30
Monocytic Leukemia, Chronic0low30
Morphine Abuse0low10
Morphine Addiction0low10
Morphine Dependence0low10
Movement Disorder Syndromes0low10
Movement Disorders0low10
Multiple Myeloma0low10
Muscle Contraction0low50
Muscle Relaxation0low50
Muscle Spasm0low10
Muscular Spasm0low10
Mycobacterium abscessus Infection0low10
Mycobacterium Infections, Atypical0low10
Mycobacterium Infections, Nontuberculous0low10
Myeloblastic Leukemia, Acute0low60
Myelocytic Leukemia0low30
Myelocytic Leukemia, Acute0low60
Myelogenous Leukemia0low30
Myelogenous Leukemia, Acute0low60
Myeloid Leukemia0low30
Myeloid Leukemia, Acute0low60
Myeloid Leukemia, Acute, M10low60
Myeloid Leukemia, Acute, M20low60
Myeloid Leukemia, Acute, M30low70
Myeloid Leukemia, Acute, M40low20
Myeloid Leukemia, Acute, M60low20
Myeloid Leukemia, Naegeli-Type0low20
Myeloma-Multiple0low10
Myeloma, Multiple0low10
Myeloma, Plasma-Cell0low10
Myelomatosis0low10
Myelomonocytic Leukemia, Acute0low20
Myocardial Hibernation0low80
Myocardial Infarct0low40
Myocardial Infarction0low40
Myocardial Ischemia0low110
Myocardial Ischemic Reperfusion Injury0low140
Myocardial Reperfusion Injury0low140
Myocardial Stunning0low80
Myoclonic Seizure0low40
Myoclonic Seizures0low40
Nagana0low10
Narcolepsy0low10
Narcolepsy-Cataplexy Syndrome0low10
Narcoleptic Syndrome0low10
Neoplasia0low30
Neoplasm0low30
Neoplasm Invasion0low20
Neoplasm Invasiveness0low20
Neoplasm Metastases0low10
Neoplasm Metastasis0low10
Neoplasms0low30
Neoplasms, Benign0low30
Neoplasms, Bladder0medium11
Neoplasms, Bone0low10
Neoplasms, Brain0low20
Neoplasms, Brain, Benign0low20
Neoplasms, Brain, Malignant0low20
Neoplasms, Brain, Primary0low20
Neoplasms, Breast0low50
Neoplasms, Colonic0low50
Neoplasms, Colorectal0low10
Neoplasms, Experimental0low30
Neoplasms, Experimental Liver0low40
Neoplasms, Intracranial0low20
Neoplasms, Lung0low10
Neoplasms, Male Genital0low10
Neoplasms, Ovarian0low10
Neoplasms, Pancreatic0low10
Neoplasms, Pulmonary0low10
Neoplastic Cell Transformation0low40
Neoplastic Transformation, Cell0low40
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Nervous System Diseases0low10
Nervous System Disorders0low10
Neuroblastoma0low40
Neurologic Disorders0low10
Neurological Disorders0low10
Neutropenia0low10
Non-Epileptic Seizure0low40
Non-Epileptic Seizures0low40
Non-Small Cell Lung Cancer0low10
Non-Small Cell Lung Carcinoma0low10
Non-Small-Cell Lung Carcinoma0low10
Nonepileptic Seizure0low40
Nonepileptic Seizures0low40
Nonlymphoblastic Leukemia, Acute0low60
Nonlymphocytic Leukemia, Acute0low60
Nonsmall Cell Lung Cancer0low10
Ocular Hypotension0low10
Ocular Hypotony0low10
Organic Mental Disorders, Substance-Induced0low10
Osteogenic Sarcoma0low20
Osteosarcoma0low20
Osteosarcoma Tumor0low20
Ovarian Cancer0low10
Ovarian Neoplasms0low10
Ovary Cancer0low10
Ovary Neoplasms0low10
Oxygen Deficiency0low60
P388D(1) Leukemia0low70
Palsy0low10
Paludism0low30
Pancreas Cancer0low10
Pancreas Neoplasms0low10
Pancreatic Cancer0low10
Pancreatic Neoplasms0low10
Paralysis0low10
Paroxysmal Sleep0low10
Partial Seizure0low40
Partial Seizures0low40
Pathologic Angiogenesis0low10
Pathologic Neovascularization0low10
Perinatal Subarachnoid Hemorrhage0low10
Petit Mal Convulsion0low40
Petit Mal Epilepsy0low10
Plasma Cell Myeloma0low10
Plasmodium falciparum Malaria0low20
Plasmodium Infections0low30
Plasmodium vivax Malaria0low10
Plegia0low10
Postabsorptive Hypoglycemia0low10
Posterior Circulation Transient Ischemic Attack0low10
Postprandial Hypoglycemia0low10
Precursor Cell Lymphoblastic Leukemia-Lymphoma0low20
Pregnancy0low130
Pregnancy in Diabetes0low20
Pregnancy in Diabetics0low20
Prenatal Exposure Delayed Effects0low10
Prescription Drug Abuse0low10
Primary Brain Neoplasms0low20
Primary Hyperthyroidism0low20
Primary Hyperuricemia Syndrome0low10
Primary Malignant Brain Neoplasms0low20
Primary Malignant Brain Tumors0low20
Progranulocytic Leukemia0low70
Prolactin Hypersecretion Syndrome0low10
Prolactin, Inappropriate Secretion0low10
Promyelocytic Leukemia, Acute0low70
Pruritis0low10
Pruritus0low10
Pulmonary Cancer0low10
Pulmonary Neoplasms0low10
Pykno-Epilepsy0low10
Pyknolepsy0low10
Reactive Hypoglycemia0low10
REM Sleep Deprivation0low30
Remittent Fever0low30
Reperfusion Damage0low20
Reperfusion Injury0low20
Reperfusion Injury, Myocardial0low140
Reticulolymphosarcoma0low140
SAH (Subarachnoid Hemorrhage)0low10
Sarcoma, Germinoblastic0low140
Sarcoma, Osteogenic0low20
Seizure0low40
Seizure Disorder0low20
Seizure Disorder, Absence0low10
Seizure Disorder, Grand Mal0low10
Seizure Disorder, Major Motor0low10
Seizure Disorder, Tonic Clonic0low10
Seizures0low40
Seizures, Auditory0low40
Seizures, Clonic0low40
Seizures, Convulsive0low40
Seizures, Epileptic0low40
Seizures, Focal0low40
Seizures, Generalized0low40
Seizures, Gustatory0low40
Seizures, Motor0low40
Seizures, Olfactory0low40
Seizures, Sensory0low40
Seizures, Somatosensory0low40
Seizures, Tonic0low40
Seizures, Tonic-Clonic0low40
Seizures, Vertiginous0low40
Seizures, Vestibular0low40
Seizures, Visual0low40
Sensitivity and Specificity0low60
Sensitivity, Contact0low10
Side Effects of Drugs0low10
Single Seizure0low40
Sleep Debt0low30
Sleep Deprivation0low30
Sleep Fragmentation0low30
Sleep Insufficiency0low30
Small-Cell Lymphoma0low20
Spasm0low10
Spasm, Ciliary Body0low10
Spasm, Generalized0low10
Status Cataplexicus0low10
Status Marmoratus0low10
Streptozocin Diabetes0low30
Streptozotocin Diabetes0low30
Stunned Myocardium0low80
Subarachnoid Hemorrhage0low10
Subarachnoid Hemorrhage, Aneurysmal0low10
Subarachnoid Hemorrhage, Intracranial0low10
Subarachnoid Hemorrhage, Spontaneous0low10
Substance Abuse0low10
Substance Addiction0low10
Substance Dependence0low10
Substance Use0low10
Substance Use Disorders0low10
Substance Withdrawal Syndrome0low30
Substance-Related Disorders0low10
Symptomatic Tonic-Clonic Epilepsy0low10
T Cell Leukemia Lymphoma, HTLV I Associated0low10
T Cell Leukemia, Adult0low10
T Lymphocytic Leukemia0low30
T-Cell Leukemia0low30
T-Cell Leukemia-Lymphoma, Adult0low10
T-Cell Leukemia-Lymphoma, HTLV-I-Associated0low10
T-Cell Leukemia, Adult0low10
T-Lymphocytic Leukemia0low30
Thalassemia Intermedia0low10
Thalassemia Major0low10
Thalassemia Major (beta-Thalassemia Major)0low10
Thalassemia Minor0low10
Thalassemia Minor (beta-Thalassemia Minor)0low10
Thalassemia, beta Type0low10
TIA (Transient Ischemic Attack)0low10
Todd Paralysis0low10
Todd's Paralysis0low10
Tonelessness Syndrome0low10
Tonic Clonic Convulsions0low10
Tonic Clonic Seizure0low40
Tonic Seizure0low40
Tonic Seizures0low40
Tonic-Clonic Convulsion Disorder0low10
Tonic-Clonic Convulsion Syndrome0low10
Tonic-Clonic Seizure0low40
Tonic-Clonic Seizure Disorder0low10
Tonic-Clonic Seizure Syndrome0low10
Tonic-Clonic Seizures0low40
Total HPRT Deficiency0low10
Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency0low10
Toxicity, Drug0low10
Transformation, Neoplastic Cell0low40
Transformation, Viral Cell0low20
Transient Ischemic Attack0low10
Transient Ischemic Attack, Anterior Circulation0low10
Transient Ischemic Attack, Brain Stem0low10
Transient Ischemic Attack, Brainstem0low10
Transient Ischemic Attack, Carotid Circulation0low10
Transient Ischemic Attack, Posterior Circulation0low10
Transient Ischemic Attack, Vertebrobasilar Circulation0low10
Transient Ischemic Attacks, Crescendo0low10
Trypanosomiasis, African0low10
Tumorigenic Transformation0low40
Tumors0low30
Tumors, Breast0low50
UDP-Galactose-4-Epimerase Deficiency0low10
UDP-Galactose-4-Epimerase Deficiency Disease0low10
UDPglucose 4-Epimerase Deficiency Disease0low10
UDPGlucose Hexose-1-Phosphate Uridylyltransferase Deficiency0low10
Urinary Bladder Cancer0medium11
Urinary Bladder Neoplasms0medium11
UTP Hexose-1-Phosphate Uridylyltransferase Deficiency0low10
UTP-Hexose-1-Phosphate Uridylyltransferase Deficiency Disease0low10
Ventricular Dysfunction, Left0low10
Ventricular Fibrillation0low40
Vertebrobasilar Circulation Transient Ischemic Attack0low10
Viral Cell Transformation0low20
Withdrawal Symptoms0low30
X-Linked Hyperuricemia0low10
X-Linked Primary Hyperuricemia0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (14)

ArticleYear
Adenosine-mediated cardiovascular toxicity in amitriptyline-poisoned rats.
Drug and chemical toxicology, Volume: 35, Issue: 4		2012
Variability in transport and biotransformation of cytarabine is associated with its toxicity in peripheral blood mononuclear cells.
Pharmacogenomics, Volume: 12, Issue: 4		2011
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.
British journal of cancer, Aug-07, Volume: 95, Issue: 3		2006
Effect of nucleoside transport inhibitors on thymidine salvage and the toxicity of nucleoside analogs in mouse bone marrow granulocyte-macrophage progenitor cells.
Cancer communications, Volume: 3, Issue: 12		1991
Inhibition of shiga toxin cytotoxicity in human renal cortical epithelial cells by nitrobenzylthioinosine.
The Journal of infectious diseases, Mar-15, Volume: 185, Issue: 6		2002
Nitrobenzylthioinosine (NBT), a nucleoside transport inhibitor, protects against Shiga toxin cytotoxicity in human microvascular endothelial cells.
Endothelium : journal of endothelial cell research, Volume: 8, Issue: 4		2001
Long-term activation of adenosine A(2a) receptors blocks glutamate excitotoxicity in cultures of avian retinal neurons.
Brain research, May-11, Volume: 900, Issue: 2		2001
Enhancement of retention and cytotoxicity of 2-chlorodeoxyadenosine in cultured human leukemic lymphoblasts by nitrobenzylthioinosine, an inhibitor of equilibrative nucleoside transport.
Leukemia, Volume: 14, Issue: 1		2000
Metabolism and selective toxicity of 6-nitrobenzylthioinosine in Toxoplasma gondii.
Antimicrobial agents and chemotherapy, Volume: 43, Issue: 10		1999
8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine.
Blood, Oct-15, Volume: 92, Issue: 8		1998
Effects of nucleoside transport inhibitors on the salvage and toxicity of adenosine and deoxyadenosine in L1210 and P388 mouse leukemia cells.
Cancer research, Volume: 45, Issue: 12 Pt 1		1985
Selective protection of tubercidin toxicity by nitrobenzyl thioinosine in normal tissues but not in human neuroblastoma cells.
Cancer chemotherapy and pharmacology, Volume: 17, Issue: 3		1986
Protection against fludarabine neurotoxicity in leukemic mice by the nucleoside transport inhibitor nitrobenzylthioinosine.
Cancer chemotherapy and pharmacology, Volume: 31, Issue: 1		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (3)

ArticleYear
The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.
The Journal of pharmacology and experimental therapeutics, Volume: 329, Issue: 1		2009
Chronic oral administration of ATP modulates nucleoside transport and purine metabolism in rats.
The Journal of pharmacology and experimental therapeutics, Volume: 294, Issue: 1		2000
Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node.
The Journal of pharmacology and experimental therapeutics, Volume: 272, Issue: 3		1995
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Measurement of nitrobenzylthioinosine in plasma and erythrocytes: a pharmacokinetic study in mice.
Cancer chemotherapy and pharmacology, Volume: 40, Issue: 4		1997
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (2)

ArticleYear
Characterization of mammalian equilibrative nucleoside transporters (ENTs) by mass spectrometry.
Protein expression and purification, Volume: 73, Issue: 1		2010
Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid.
Leukemia research, Volume: 31, Issue: 7		2007
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (8)

ArticleYear
Roles of organic anion transporter 2 and equilibrative nucleoside transporter 1 in hepatic disposition and antiviral activity of entecavir during non-pregnancy and pregnancy.
British journal of pharmacology, Volume: 176, Issue: 17		2019
Nucleoside transport inhibition and platelet aggregation in human blood: R75231 and its enantiomers, draflazine and R88016.
European journal of pharmacology, Jan-01, Volume: 266, Issue: 1		1994
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C.
The Biochemical journal, Jun-01, Volume: 300 ( Pt 2)		1994
Sensitivity to inhibition by N-ethylmaleimide: a property of nitrobenzylthioinosine-sensitive equilibrative nucleoside transporter of murine myeloma cells.
Biochimica et biophysica acta, Aug-31, Volume: 1268, Issue: 2		1995
Treatment of mouse neoplasms with high doses of tubercidin.
Cancer research, Volume: 41, Issue: 8		1981
Selective protection of tubercidin toxicity by nitrobenzyl thioinosine in normal tissues but not in human neuroblastoma cells.
Cancer chemotherapy and pharmacology, Volume: 17, Issue: 3		1986
Nucleoside transport in rat cerebral-cortical synaptosomes. Evidence for two types of nucleoside transporters.
The Biochemical journal, Jan-15, Volume: 249, Issue: 2		1988
Protection of mice against lethal dosages of nebularine by nitrobenzylthioinosine, an inhibitor of nucleoside transport.
Cancer research, Volume: 39, Issue: 9		1979
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (2)

ArticleYear
Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1.
Drug metabolism and disposition: the biological fate of chemicals, Volume: 49, Issue: 7		2021
Experimental chemotherapy of leishmaniasis with adenosine analogue Formycin A, in combination with inhibitor of nucleoside transport, nitrobenzylthioinosinate.
Drugs under experimental and clinical research, Volume: 18, Issue: 10		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]