Page last updated: 2024-08-07 17:31:44
Transporter
[no definition available]
Synonyms
Research
Bioassay Publications (61)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 6 (9.84) | 18.7374 |
| 1990's | 19 (31.15) | 18.2507 |
| 2000's | 32 (52.46) | 29.6817 |
| 2010's | 3 (4.92) | 24.3611 |
| 2020's | 1 (1.64) | 2.80 |
Compounds (74)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| epibatidine | Rattus norvegicus (Norway rat) | Ki | 0.0001 | 1 | 2 |
| 8-hydroxy-2-(di-n-propylamino)tetralin | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| 3-aminobenzamide | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| tacrine | Rattus norvegicus (Norway rat) | IC50 | 16.5000 | 2 | 2 |
| citalopram | Rattus norvegicus (Norway rat) | IC50 | 8.8000 | 1 | 1 |
| citalopram | Rattus norvegicus (Norway rat) | Ki | 6.1900 | 1 | 1 |
| cyproheptadine | Rattus norvegicus (Norway rat) | Ki | 0.2900 | 1 | 1 |
| desipramine | Rattus norvegicus (Norway rat) | IC50 | 10.6500 | 2 | 2 |
| desipramine | Rattus norvegicus (Norway rat) | Ki | 0.0074 | 2 | 3 |
| fluoxetine | Rattus norvegicus (Norway rat) | Ki | 0.7943 | 1 | 1 |
| vanoxerine | Rattus norvegicus (Norway rat) | IC50 | 0.1140 | 1 | 1 |
| vanoxerine | Rattus norvegicus (Norway rat) | Ki | 4.5442 | 5 | 5 |
| velnacrine | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 2 | 2 |
| imipramine | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 1 | 1 |
| imipramine | Rattus norvegicus (Norway rat) | Ki | 0.0160 | 1 | 1 |
| mazindol | Rattus norvegicus (Norway rat) | Ki | 0.0008 | 1 | 1 |
| mianserin | Rattus norvegicus (Norway rat) | IC50 | 0.0220 | 1 | 2 |
| mianserin | Rattus norvegicus (Norway rat) | Ki | 0.1010 | 1 | 1 |
| mirtazapine | Rattus norvegicus (Norway rat) | IC50 | 0.5067 | 2 | 3 |
| mirtazapine | Rattus norvegicus (Norway rat) | Ki | 1.6400 | 1 | 1 |
| modafinil | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| modafinil | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| nisoxetine | Rattus norvegicus (Norway rat) | Ki | 0.0057 | 2 | 2 |
| nomifensine | Rattus norvegicus (Norway rat) | IC50 | 2.7033 | 2 | 2 |
| oxidopamine | Rattus norvegicus (Norway rat) | Ki | 0.0510 | 1 | 1 |
| risperidone | Rattus norvegicus (Norway rat) | Ki | 5.4540 | 1 | 1 |
| venlafaxine | Rattus norvegicus (Norway rat) | Ki | 0.7190 | 1 | 1 |
| vancomycin | Rattus norvegicus (Norway rat) | Ki | 0.0158 | 1 | 1 |
| talopram | Rattus norvegicus (Norway rat) | IC50 | 0.0029 | 1 | 1 |
| talopram | Rattus norvegicus (Norway rat) | Ki | 0.0045 | 1 | 1 |
| talsupram | Rattus norvegicus (Norway rat) | IC50 | 0.0008 | 1 | 1 |
| paroxetine | Rattus norvegicus (Norway rat) | IC50 | 0.5350 | 1 | 1 |
| paroxetine | Rattus norvegicus (Norway rat) | Ki | 0.6596 | 1 | 1 |
| rimcazole | Rattus norvegicus (Norway rat) | Ki | 2.1600 | 2 | 2 |
| atomoxetine | Rattus norvegicus (Norway rat) | Ki | 0.0050 | 1 | 2 |
| (S)-nomifensine | Rattus norvegicus (Norway rat) | IC50 | 0.0066 | 1 | 1 |
| sertraline hydrochloride | Rattus norvegicus (Norway rat) | IC50 | 0.0700 | 1 | 1 |
| sertraline | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 1 | 2 |
| atipamezole | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| nicotine | Rattus norvegicus (Norway rat) | Ki | 5.5000 | 1 | 1 |
| 2,4,5-trihydroxyamphetamine | Rattus norvegicus (Norway rat) | Ki | 0.0260 | 1 | 1 |
| 5-amino-2,4-dihydroxy-alpha-methylphenylethylamine | Rattus norvegicus (Norway rat) | Ki | 0.0460 | 1 | 1 |
| dexmethylphenidate hydrochloride | Rattus norvegicus (Norway rat) | Ki | 0.2700 | 1 | 1 |
| dexmethylphenidate | Rattus norvegicus (Norway rat) | IC50 | 0.9890 | 1 | 1 |
| harmalan | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| 6-aminodopamine | Rattus norvegicus (Norway rat) | Ki | 0.0110 | 1 | 1 |
| 1-methyl-6-methoxy-dihydro-beta-carboline | Rattus norvegicus (Norway rat) | Ki | 4.1000 | 1 | 1 |
| cocaine | Rattus norvegicus (Norway rat) | IC50 | 3.2277 | 13 | 15 |
| cocaine | Rattus norvegicus (Norway rat) | Ki | 2.3643 | 15 | 18 |
| tropisetron | Rattus norvegicus (Norway rat) | Ki | 27.0000 | 1 | 1 |
| cocaine hydrochloride | Rattus norvegicus (Norway rat) | Ki | 1.9300 | 1 | 1 |
| etomidate | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |
| (R)-fluoxetine | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| 2-[(2-ethoxyphenoxy)-phenylmethyl]morpholine | Rattus norvegicus (Norway rat) | Ki | 0.0074 | 2 | 2 |
| amiflamine | Rattus norvegicus (Norway rat) | IC50 | 0.6500 | 1 | 1 |
| rs-130830 | Rattus norvegicus (Norway rat) | IC50 | 0.0140 | 1 | 2 |
| 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane | Rattus norvegicus (Norway rat) | Ki | 0.6100 | 1 | 1 |
| harmine | Rattus norvegicus (Norway rat) | Ki | 3.2600 | 1 | 1 |
| fluvoxamine | Rattus norvegicus (Norway rat) | IC50 | 0.5400 | 1 | 1 |
| zimeldine | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| pepstatin | Rattus norvegicus (Norway rat) | Ki | 36.5000 | 1 | 1 |
| [2-[[2-[(dimethylamino)methyl]phenyl]thio]-5-iodophenyl]methanol | Rattus norvegicus (Norway rat) | Ki | 0.2340 | 1 | 1 |
| methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate | Rattus norvegicus (Norway rat) | Ki | 0.2520 | 1 | 1 |
| n,n-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine | Rattus norvegicus (Norway rat) | Ki | 0.3250 | 1 | 1 |
| methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate | Rattus norvegicus (Norway rat) | IC50 | 0.2520 | 1 | 1 |
| methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate | Rattus norvegicus (Norway rat) | Ki | 0.2520 | 2 | 2 |
| 9-(aminomethyl)-9,10-dihydroanthracene | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine | Rattus norvegicus (Norway rat) | Ki | 0.6830 | 1 | 1 |
| (1R,3S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid methyl ester | Rattus norvegicus (Norway rat) | IC50 | 0.0360 | 2 | 2 |
| (1R,3S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid methyl ester | Rattus norvegicus (Norway rat) | Ki | 0.0216 | 1 | 1 |
| win 35,065-2 | Rattus norvegicus (Norway rat) | IC50 | 2.0850 | 1 | 1 |
| clozapine | Rattus norvegicus (Norway rat) | Ki | 0.6970 | 1 | 1 |
| olanzapine | Rattus norvegicus (Norway rat) | Ki | 0.9580 | 1 | 1 |
| asoxime chloride | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| pralidoxime chloride | Rattus norvegicus (Norway rat) | IC50 | 1,200.0000 | 1 | 1 |
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| epibatidine | Rattus norvegicus (Norway rat) | K app | 0.0000 | 1 | 1 |
| nicotine | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 1 |
Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues.Journal of medicinal chemistry, , Mar-13, Volume: 46, Issue:6, 2003
Emerging molecular approaches to pain therapy.Journal of medicinal chemistry, , May-06, Volume: 42, Issue:9, 1999
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.Journal of medicinal chemistry, , Jul-18, Volume: 40, Issue:15, 1997
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.Journal of medicinal chemistry, , Feb-26, Volume: 47, Issue:5, 2004
3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition of dopamine, norepinephrine, and serotonin uptake.Journal of medicinal chemistry, , Volume: 28, Issue:12, 1985
Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants.Bioorganic & medicinal chemistry letters, , May-16, Volume: 15, Issue:10, 2005
Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors.Bioorganic & medicinal chemistry letters, , Oct-20, Volume: 13, Issue:20, 2003
9-Amino-1,2,3,4-tetrahydroacridin-1-ols: synthesis and evaluation as potential Alzheimer's disease therapeutics.Journal of medicinal chemistry, , Volume: 32, Issue:8, 1989
Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.Journal of medicinal chemistry, , Jul-28, Volume: 48, Issue:15, 2005
Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.Journal of medicinal chemistry, , Apr-10, Volume: 46, Issue:8, 2003
[3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.Bioorganic & medicinal chemistry letters, , Dec-17, Volume: 11, Issue:24, 2001
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.Journal of medicinal chemistry, , Oct-21, Volume: 42, Issue:21, 1999
N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.Journal of medicinal chemistry, , Jan-19, Volume: 39, Issue:2, 1996
Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.Bioorganic & medicinal chemistry letters, , Mar-12, Volume: 11, Issue:5, 2001
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.Journal of medicinal chemistry, , Volume: 27, Issue:11, 1984
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.Journal of medicinal chemistry, , Mar-24, Volume: 48, Issue:6, 2005
Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine.Journal of medicinal chemistry, , Jul-18, Volume: 45, Issue:15, 2002
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.Journal of medicinal chemistry, , Mar-24, Volume: 48, Issue:6, 2005
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.Journal of medicinal chemistry, , Dec-04, Volume: 46, Issue:25, 2003
Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine.Journal of medicinal chemistry, , Jul-18, Volume: 45, Issue:15, 2002
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges.Journal of medicinal chemistry, , 03-22, Volume: 61, Issue:6, 2018
Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.Journal of medicinal chemistry, , Nov-18, Volume: 47, Issue:24, 2004
Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram.RSC medicinal chemistry, , Jul-21, Volume: 12, Issue:7, 2021
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.Journal of medicinal chemistry, , Dec-04, Volume: 46, Issue:25, 2003
Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram.RSC medicinal chemistry, , Jul-21, Volume: 12, Issue:7, 2021
3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition of dopamine, norepinephrine, and serotonin uptake.Journal of medicinal chemistry, , Volume: 28, Issue:12, 1985
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.Journal of medicinal chemistry, , Dec-04, Volume: 46, Issue:25, 2003
Synthesis and ligand binding of tropane ring analogues of paroxetine.Journal of medicinal chemistry, , Jan-15, Volume: 41, Issue:2, 1998
[3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.Bioorganic & medicinal chemistry letters, , Dec-17, Volume: 11, Issue:24, 2001
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.Journal of medicinal chemistry, , Oct-21, Volume: 42, Issue:21, 1999
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.Bioorganic & medicinal chemistry letters, , Feb-12, Volume: 11, Issue:3, 2001
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.Journal of medicinal chemistry, , Jul-18, Volume: 40, Issue:15, 1997
(S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Aug-16, Volume: 39, Issue:17, 1996
Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.Journal of medicinal chemistry, , Jan-15, Volume: 47, Issue:2, 2004
Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.Journal of medicinal chemistry, , Nov-18, Volume: 47, Issue:24, 2004
Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.Journal of medicinal chemistry, , May-08, Volume: 46, Issue:10, 2003
Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors.Bioorganic & medicinal chemistry letters, , Oct-20, Volume: 13, Issue:20, 2003
2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy.Journal of medicinal chemistry, , May-08, Volume: 46, Issue:10, 2003
Thiophene derivatives: a new series of potent norepinephrine and serotonin reuptake inhibitors.Bioorganic & medicinal chemistry letters, , Apr-08, Volume: 12, Issue:7, 2002
SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.Journal of medicinal chemistry, , Jul-18, Volume: 45, Issue:15, 2002
Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles.Bioorganic & medicinal chemistry letters, , Aug-20, Volume: 11, Issue:16, 2001
Pharmacophore-based discovery of 3,4-disubstituted pyrrolidines as a novel class of monoamine transporter inhibitors.Bioorganic & medicinal chemistry letters, , May-07, Volume: 11, Issue:9, 2001
An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-(p-fluorophenyl)-2-propyltropanes.Bioorganic & medicinal chemistry letters, , Jul-03, Volume: 10, Issue:13, 2000
Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationshiJournal of medicinal chemistry, , Feb-10, Volume: 43, Issue:3, 2000
3alpha-(4-Substituted phenyl)nortropane-2beta-carboxylic acid methyl esters show selective binding at the norepinephrine transporter.Bioorganic & medicinal chemistry letters, , Nov-06, Volume: 10, Issue:21, 2000
Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.Journal of medicinal chemistry, , May-18, Volume: 43, Issue:10, 2000
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.Journal of medicinal chemistry, , Oct-21, Volume: 42, Issue:21, 1999
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.Journal of medicinal chemistry, , Nov-18, Volume: 42, Issue:23, 1999
Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes.Bioorganic & medicinal chemistry letters, , Dec-15, Volume: 8, Issue:24, 1998
2beta-Substituted analogues of 4'-iodococaine: synthesis and dopamine transporter binding potencies.Journal of medicinal chemistry, , Jun-18, Volume: 41, Issue:13, 1998
Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.Journal of medicinal chemistry, , Apr-11, Volume: 40, Issue:8, 1997
3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.Journal of medicinal chemistry, , Nov-21, Volume: 40, Issue:24, 1997
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.Journal of medicinal chemistry, , Sep-27, Volume: 39, Issue:20, 1996
N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.Journal of medicinal chemistry, , Jan-19, Volume: 39, Issue:2, 1996
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.Journal of medicinal chemistry, , Oct-11, Volume: 39, Issue:21, 1996
Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.Journal of medicinal chemistry, , Sep-01, Volume: 38, Issue:18, 1995
Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.Journal of medicinal chemistry, , Apr-15, Volume: 37, Issue:8, 1994
Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.Journal of medicinal chemistry, , Jun-26, Volume: 35, Issue:13, 1992
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.Journal of medicinal chemistry, , Feb-26, Volume: 47, Issue:5, 2004
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.Journal of medicinal chemistry, , Dec-04, Volume: 46, Issue:25, 2003
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges.Journal of medicinal chemistry, , 03-22, Volume: 61, Issue:6, 2018
SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.Journal of medicinal chemistry, , Jul-18, Volume: 45, Issue:15, 2002
Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles.Bioorganic & medicinal chemistry letters, , Aug-20, Volume: 11, Issue:16, 2001
2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy.Journal of medicinal chemistry, , May-08, Volume: 46, Issue:10, 2003
Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.Journal of medicinal chemistry, , Apr-15, Volume: 37, Issue:8, 1994