Proteins > Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Page last updated: 2024-08-07 13:11:55
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
A protein that is a translation product of the RAM2 gene in yeast. [PRO:DNx, UniProtKB:P29703]
Synonyms
PFTase/PGGTase I alpha;
EC 2.5.1.58;
EC 2.5.1.59;
CAAX farnesyltransferase subunit alpha;
FTase-alpha;
Ras proteins prenyltransferase subunit alpha;
Type I protein geranyl-geranyltransferase subunit alpha;
GGTase-I-alpha
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| fti 276 | Saccharomyces cerevisiae S288C | IC50 | 0.0008 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| farnesyl pyrophosphate | Saccharomyces cerevisiae S288C | Km | 27.0000 | 1 | 1 |