Page last updated: 2024-08-07 12:56:58
2-dehydropantoate 2-reductase
A 2-dehydropantoate 2-reductase that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A9J4]
Synonyms
EC 1.1.1.169;
Ketopantoate reductase;
KPA reductase;
KPR
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| phosphoric acid | Escherichia coli K-12 | Ki | 27,000.0000 | 1 | 1 |
| adenosine diphosphate | Escherichia coli K-12 | Ki | 1,050.0000 | 1 | 1 |
| adenosine monophosphate | Escherichia coli K-12 | Ki | 6,300.0000 | 1 | 1 |
| adenosine 2',5'-diphosphate | Escherichia coli K-12 | Ki | 240.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| nadp | Escherichia coli K-12 | Kd | 0.2600 | 1 | 1 |
| nad | Escherichia coli K-12 | Kd | 6,900.0000 | 1 | 1 |
| adenosine diphosphate | Escherichia coli K-12 | Kd | 360.0000 | 1 | 1 |
| adenosine monophosphate | Escherichia coli K-12 | Kd | 5,000.0000 | 1 | 1 |
| adenosine 2',5'-diphosphate | Escherichia coli K-12 | Kd | 100.0000 | 1 | 1 |
| guanosine diphosphate | Escherichia coli K-12 | Kd | 373.0000 | 1 | 1 |
| guanosine triphosphate | Escherichia coli K-12 | Kd | 153.0000 | 1 | 1 |