Agropine is a naturally occurring compound produced by the bacterium Agrobacterium tumefaciens. It is a derivative of the amino acid arginine and plays a role in the crown gall disease, a plant disease caused by A. tumefaciens. Agropine is synthesized by the bacterium from arginine through a series of enzymatic steps. It acts as a signaling molecule, influencing the growth and development of the crown gall tumor. Agropine is important for understanding the molecular mechanisms involved in plant-microbe interactions and the development of crown gall disease. Studying agropine helps researchers gain insights into the bacterial virulence factors and the plant defense mechanisms involved in this disease. Agropine also has potential applications in biotechnology as a marker for A. tumefaciens infection and for the development of new agricultural strategies.'
agropine: RN given refers to (S)-isomer; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 121936 |
| MeSH ID | M0085823 |
| Synonym |
|---|
| agropine |
| 70699-77-3 |
| 3-[(3s,6r)-2-oxo-6-[(1s,2r,3r)-1,2,3,4-tetrahydroxybutyl]morpholin-3-yl]propanamide |
| 1h-pyrrolo(2,1-c)(1,4)oxazine-1,6(7h)-dione, tetrahydro-3-(1,2,3,4-tetrahydroxybutyl)- |
| d-mannitol, 1-((4-amino-1-carboxy-4-oxobutyl)amino)-1-deoxy-, intermol. 1,2-ester, (s)- |
| (1'-deoxy-d-mannitol-1'-yl)-l-glutamine,1',2'-lactone |
| 3-[2-oxo-6-(1,2,3,4-tetrahydroxybutyl)morpholin-3-yl]propanimidic acid |
| DTXSID70990949 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8 (28.57) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (26.98) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (3.45%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 28 (96.55%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||