Proteins > glycogen synthase kinase-3 alpha
Page last updated: 2024-08-07 15:19:49

glycogen synthase kinase-3 alpha

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (167)

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
coumarinHomo sapiens (human)AC50300.000010
acridoneHomo sapiens (human)AC50300.000010
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolHomo sapiens (human)AC5086.930010
gw8510Homo sapiens (human)AC500.188020
4-chlorobenzoic acidHomo sapiens (human)AC50300.000010
1-amino-2-methylanthraquinoneHomo sapiens (human)AC50300.000010
3-aminobenzoic acidHomo sapiens (human)AC50300.000010
2-aminoanthraquinoneHomo sapiens (human)AC50300.000010
n-acetyl-2-toluidineHomo sapiens (human)AC50300.000010
2-amino-5-nitrothiazoleHomo sapiens (human)AC50300.000010
aloe emodinHomo sapiens (human)AC50300.000010
flavoneHomo sapiens (human)AC50300.000010
2-phenylbenzimidazoleHomo sapiens (human)AC50300.000010
indole-3-acetic acid ethyl esterHomo sapiens (human)AC50300.000010
2-(alpha-thenoylamino)-2-nitro-5-thiazoleHomo sapiens (human)AC5042.580010
cetyldimethylethylammonium bromideHomo sapiens (human)AC50300.000010
flunixin meglumineHomo sapiens (human)AC50300.000010
3-carboxy-thioxanthone-10,10-dioxideHomo sapiens (human)AC5038.320010
4-methylquinolin-2(1H)-oneHomo sapiens (human)AC50300.000010
7-bromo-5-phenyl-1,2-dihydro-2h-1,4-benzodiazepin-2-oneHomo sapiens (human)AC5034.180010
4'-methoxyflavoneHomo sapiens (human)AC50300.000010
2-(1H-benzimidazol-2-yl)anilineHomo sapiens (human)AC50300.000010
4-nitrophenyl dimethylcarbamateHomo sapiens (human)AC50300.000010
8-(4-tolylsulfonylamino)quinolineHomo sapiens (human)AC50300.000010
7-(diethylamino)-1-benzopyran-2-oneHomo sapiens (human)AC50300.000010
9-methoxyacridineHomo sapiens (human)AC50300.000010
lecanoric acidHomo sapiens (human)AC5027.800010
karanjinHomo sapiens (human)AC5039.550010
ZearalanoneHomo sapiens (human)AC5028.260010
ak 2123Homo sapiens (human)AC50300.000010
gyrophoric acidHomo sapiens (human)AC50300.000010
Ethyl 2,5-dimethyl-1H-pyrrole-3-carboxylateHomo sapiens (human)AC50300.000010
sb 216763Homo sapiens (human)AC500.020010
moracin mHomo sapiens (human)AC50300.000010
(7R)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-oneHomo sapiens (human)AC50300.000010
anthraquinone 1-carboxylic acidHomo sapiens (human)AC50300.000010
1-Anilino-9,10-dioxo-2-anthroic acidHomo sapiens (human)AC5018.580010
2-methyl-3-(phenylthio)pyrazineHomo sapiens (human)AC50300.000010
4-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)methylamino]benzoic acidHomo sapiens (human)AC50300.000010
nsc 95397Homo sapiens (human)AC50300.000010
oxopurpureineHomo sapiens (human)AC5037.080010
1-(4-chlorophenyl)-3-(2-ethoxyphenyl)ureaHomo sapiens (human)AC50300.000010
dicentrineHomo sapiens (human)AC5024.930010
6-dimethylaminopurine arabinosideHomo sapiens (human)AC50300.000010
6-bromoindirubin-3'-oximeHomo sapiens (human)AC500.013510
7-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-oneHomo sapiens (human)AC5039.000010
2-[(4,4-dimethyl-2,6-dioxocyclohexyl)-(3-pyridinyl)methyl]-5,5-dimethylcyclohexane-1,3-dioneHomo sapiens (human)AC50300.000010
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanoneHomo sapiens (human)AC5015.590010
4-(4-fluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid 1,3-benzodioxol-5-ylmethyl esterHomo sapiens (human)AC5020.260010
3-acetamido-5-chloro-2-benzofurancarboxylic acidHomo sapiens (human)AC5070.370010
haplamineHomo sapiens (human)AC5010.430010
6-ethyl-2,5-dimethyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrileHomo sapiens (human)AC5039.350010
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-methoxyacetamideHomo sapiens (human)AC5058.970010
2-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-2-phenylacetonitrileHomo sapiens (human)AC503.351010
5-(3-butoxyphenyl)-1,3,4-thiadiazol-2-amineHomo sapiens (human)AC5046.140010
3-benzamido-5-bromo-2-benzofurancarboxylic acid methyl esterHomo sapiens (human)AC50300.000010
N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideHomo sapiens (human)AC5035.520010
2-[[(4-methyl-2-thiazolyl)amino]-oxomethyl]-1-pyrrolidinecarboxylic acid 2-methylpropyl esterHomo sapiens (human)AC50300.000010
3-(2-furanylmethyl)-8-(4-methoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrileHomo sapiens (human)AC5045.420010
3,3',4,5'-tetrahydroxystilbeneHomo sapiens (human)AC5038.780010
7-[(3,5-dimethyl-4-isoxazolyl)methoxy]-1-benzopyran-2-oneHomo sapiens (human)AC50300.000010
4-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamideHomo sapiens (human)AC50300.000010
N-(3-pyridinyl)-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-carboxamideHomo sapiens (human)AC5023.530010
N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amineHomo sapiens (human)AC50164.860020
3-propyl-1-(2-pyridinylmethylamino)-4-pyrido[1,2-a]benzimidazolecarbonitrileHomo sapiens (human)AC50300.000010
N-(6-ethoxy-1,3-benzothiazol-2-yl)butanamideHomo sapiens (human)AC5035.840010
2-chloro-N-[5-ethyl-3-[(4-methylphenyl)-oxomethyl]-2-thiophenyl]acetamideHomo sapiens (human)AC50300.000010
7-acetoxycoumarinHomo sapiens (human)AC50300.000010
4-[2-(3-methoxyanilino)-4-thiazolyl]phenolHomo sapiens (human)AC5063.655020
4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl esterHomo sapiens (human)AC5060.620010
N-(2-methoxyphenyl)-3-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]propanamideHomo sapiens (human)AC5095.610010
5-bromo-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamideHomo sapiens (human)AC50300.000010
3-[[4-(1,3-benzodioxol-5-yl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-N-(2-furanylmethyl)propanamideHomo sapiens (human)AC50300.000010
7-(diethylaminomethyl)-1-(4-methoxyphenyl)-2-methyl-3-nitro-6-indololHomo sapiens (human)AC5038.220010
N-[(4-ethylanilino)-sulfanylidenemethyl]-3-methylbutanamideHomo sapiens (human)AC50300.000010
5-bromo-N-[3-chloro-2-(1-pyrrolidinyl)phenyl]-2-furancarboxamideHomo sapiens (human)AC50300.000010
2-acetamido-5-propyl-3-thiophenecarboxamideHomo sapiens (human)AC5030.810010
5-methyl-4-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxymethyl]-2-furancarboxylic acidHomo sapiens (human)AC5021.630010
N-[6-methoxy-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-3-methylbutanamideHomo sapiens (human)AC501.480010
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl esterHomo sapiens (human)AC504.240010
1-ethyl-3-[(1-oxo-2-phenylethyl)amino]thioureaHomo sapiens (human)AC50300.000010
tg 003Homo sapiens (human)AC5016.470010
2,2-diphenylacetic acid (2,6-dimethylphenyl) esterHomo sapiens (human)AC50300.000010
1-(1,3-benzodioxol-5-ylmethylthio)-[1,2,4]triazolo[4,3-a]quinolineHomo sapiens (human)AC50300.000010
5,6-dimethyl-N-(thiophen-2-ylmethyl)-4-thieno[2,3-d]pyrimidinamineHomo sapiens (human)AC50300.000010
3-[4-(4-morpholinylsulfonyl)phenyl]propanoic acid [2-[(5-chloro-2-pyridinyl)amino]-2-oxoethyl] esterHomo sapiens (human)AC5028.440010
[9-(4-ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanoneHomo sapiens (human)AC50300.000010
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]acetic acid ethyl esterHomo sapiens (human)AC50300.000010
1-(5-isoquinolinyl)-3-(2-phenylethyl)thioureaHomo sapiens (human)AC50300.000010
2-(1,3-benzoxazol-2-ylthio)-N-(6-bromo-1,3-benzothiazol-2-yl)acetamideHomo sapiens (human)AC50300.000010
2-chloro-N-[4-[(3,4-dimethylphenyl)thio]phenyl]acetamideHomo sapiens (human)AC50300.000010
5-(3,4-dimethoxyphenyl)-2-methyl-4-(4-methyl-1-piperidinyl)thieno[2,3-d]pyrimidineHomo sapiens (human)AC50300.000010
2-chloro-N-[3-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-3-oxopropyl]benzamideHomo sapiens (human)AC508.010010
5-[[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]methyl]-2-furancarboxylic acid methyl esterHomo sapiens (human)AC50300.000010
N-(5-methyl-2-thiazolyl)cyclopentanecarboxamideHomo sapiens (human)AC50171.700010
2,2-dimethyl-N-pyridin-4-yl-3H-benzofuran-7-carboxamideHomo sapiens (human)AC505.805010
7-(3-hydroxyphenyl)-5-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl esterHomo sapiens (human)AC5022.900010
(4-chlorophenyl)-[6,7-dichloro-4-[(dimethylamino)methyl]-5-hydroxy-2-methyl-3-benzofuranyl]methanoneHomo sapiens (human)AC507.713010
LSM-20517Homo sapiens (human)AC50300.000010
1,3,8-trimethyl-5,10-diphenylpyrimido[1,2]pyrrolo[4,5-b]pyridazine-2,4-dioneHomo sapiens (human)AC50300.000010
6-amino-4-(2-furanyl)-3-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrileHomo sapiens (human)AC50300.000010
N-(3-carbamoyl-5-propyl-2-thiophenyl)-2-oxolanecarboxamideHomo sapiens (human)AC50300.000010
zeranolHomo sapiens (human)AC5087.540010
5-[[[5-(2,3-dihydro-1,4-benzodioxin-3-yl)-4-methyl-1,2,4-triazol-3-yl]thio]methyl]-2-phenylthiazoleHomo sapiens (human)AC50300.000010
N-[2-[5-[(4-tert-butylphenyl)methylthio]-1,3,4-oxadiazol-2-yl]phenyl]benzamideHomo sapiens (human)AC50300.000010
9-chloro-6-methylindolo[3,2-b]quinoxalineHomo sapiens (human)AC50300.000010
6-(3,4-dimethoxyphenyl)-4-oxo-3-phenyl-1,5,6,7-tetrahydroindole-2-carboxylic acid ethyl esterHomo sapiens (human)AC5060.890010
uccf-029Homo sapiens (human)AC500.312110
LSM-18934Homo sapiens (human)AC5015.260010
5-amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-(2-methoxyphenyl)-4-triazolecarboxamideHomo sapiens (human)AC5014.830010
4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-imidazo[1,2-a]pyrimidinyl]phenolHomo sapiens (human)AC50300.000010
3-(2-chlorophenyl)-5-methyl-N-[3-(3-methyl-2-imidazo[1,2-a]pyrimidinyl)phenyl]-4-isoxazolecarboxamideHomo sapiens (human)AC50300.000010
LSM-16579Homo sapiens (human)AC501.982010
N4-(3,4-dimethylphenyl)-2-(4-ethyl-1-piperazinyl)-5-nitropyrimidine-4,6-diamineHomo sapiens (human)AC50300.000010
N4-(2-furanylmethyl)-N2-(3-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamineHomo sapiens (human)AC505.754010
N4-(3-fluorophenyl)-N2-[3-(4-morpholinyl)propyl]-5-nitropyrimidine-2,4,6-triamineHomo sapiens (human)AC500.698010
3-nitro-N-(2-phenylethyl)-2-pyridinamineHomo sapiens (human)AC50300.000010
2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamideHomo sapiens (human)AC50300.000010
8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trioneHomo sapiens (human)AC50300.000010
2-(4-phenyl-1-piperazinyl)quinoxalineHomo sapiens (human)AC50300.000010
4-(2-fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-1,2,4-triazol-3-oneHomo sapiens (human)AC50300.000010
7-methoxy-2-phenylimino-1-benzopyran-3-carboxamideHomo sapiens (human)AC50300.000010
N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamideHomo sapiens (human)AC50300.000010
LSM-27960Homo sapiens (human)AC50300.000010
N-(1,3-dioxo-4-isoindolyl)-2-(2,5-dioxo-1-pyrrolidinyl)acetamideHomo sapiens (human)AC500.459010
N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)anilineHomo sapiens (human)AC50300.000010
2-(2-furanyl)-4-mercapto-3-(4-methylphenyl)-6-oxo-1,2-dihydropyrimidine-5-carbonitrileHomo sapiens (human)AC50300.000010
LSM-1646Homo sapiens (human)AC508.662010
acacetinHomo sapiens (human)AC504.207010
quercitrinHomo sapiens (human)AC5029.770010
chrysoeriolHomo sapiens (human)AC503.648010
quercetin 3-o-methyl etherHomo sapiens (human)AC501.927010
3-methylkaempferolHomo sapiens (human)AC506.968010
sulfuretinHomo sapiens (human)AC5010.510010
myricetinHomo sapiens (human)AC504.133010
santinHomo sapiens (human)AC50300.000010
astragalinHomo sapiens (human)AC5030.360010
2-[2-[[[1-(1H-imidazol-5-ylsulfonyl)-3-piperidinyl]-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl esterHomo sapiens (human)AC50300.000010
8-methyl-1-[2-(2-methyl-1-piperidinyl)-2-oxoethyl]-4-[1]benzopyrano[4,3-c]pyrazoloneHomo sapiens (human)AC50300.000010
3-(4-fluorophenyl)-6-(1-pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazineHomo sapiens (human)AC505.640010
1-(4-morpholinyl)-2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]ethanoneHomo sapiens (human)AC50300.000010
2-[[cyclohexyl(oxo)methyl]amino]-3-thiophenecarboxamideHomo sapiens (human)AC50300.000010
IsolicoflavonolHomo sapiens (human)AC509.402010
semaxinibHomo sapiens (human)AC50300.000010
7-hydroxy-4-methyl-1H-quinolin-2-oneHomo sapiens (human)AC50300.000010
urolithin bHomo sapiens (human)AC50300.000010
baohuoside iiHomo sapiens (human)AC5019.610010
3,3'-diethylthiacarbocyanine iodideHomo sapiens (human)AC5024.610010
chloride of pseudoisocyanineHomo sapiens (human)AC5066.140010
5233705 compoundHomo sapiens (human)AC50300.000010
beta-zearalenolHomo sapiens (human)AC5033.800010
N-[5-(2-imidazo[1,2-a]pyrimidinyl)-2-methoxyphenyl]-2-methylpropanamideHomo sapiens (human)AC50300.000010
2-chloro-N-[3-(2-thiazolo[5,4-b]pyridinyl)phenyl]-3-pyridinecarboxamideHomo sapiens (human)AC508.587010
N-(1,3-dioxo-5-isoindolyl)butanamideHomo sapiens (human)AC5031.800010
2-[4-ethoxy-2-[2-furanyl(oxo)methyl]imino-1,3-benzothiazol-3-yl]acetic acid methyl esterHomo sapiens (human)AC507.605010
chlorhexidineHomo sapiens (human)AC50162.800010
fursultiamin monohydrochlorideHomo sapiens (human)AC50300.000010
kaempferol 3-O-beta-L-glucopyranosideHomo sapiens (human)AC5032.790010
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanoneHomo sapiens (human)AC50300.000010
N-[[5-(2,4-difluorophenyl)-1H-pyrazol-4-yl]methyl]-1-(3-thiophenyl)-2-propanamineHomo sapiens (human)AC5077.130010
violaceol IIHomo sapiens (human)AC50300.000010
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acidHomo sapiens (human)AC50300.000010
4-[[4-(2-methoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]-1-butanolHomo sapiens (human)AC50300.000010
N-[(2S,3S)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamideHomo sapiens (human)AC50300.000010
2-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methylthio]-6-phenyl-1H-pyrimidin-4-oneHomo sapiens (human)AC50300.000010
7-hydroxyquinolineHomo sapiens (human)AC50300.000010
7-(4-chlorophenyl)-5-(4-ethylphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amineHomo sapiens (human)AC50300.000010