delavirdine has been researched along with Sensitivity and Specificity in 4 studies
Delavirdine: A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
delavirdine : The amide resulting from the formal condensation of 5-[(methylsulfonyl)amino]-1H-indole-2-carboxylic acid and 4-amino group of 1-[3-(isopropylamino)pyridin-2-yl]piperazine, delavirdine is a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Delavirdine is a newly developed anti-HIV-1 drug for AIDS therapy." | 1.31 | Determination of delavirdine in very small volumes of plasma by high-performance liquid chromatography with fluorescence detection. ( Cheng, CL; Chou, CH; Hu, OY, 2002) |
| "Delavirdine is a novel non-nucleoside reverse transcriptase inhibitor for the treatment of HIV-1-infected patients." | 1.30 | Rapid quantification of delavirdine, a novel non-nucleoside reverse transcriptase inhibitor, in human plasma using isocratic reversed-phase high-performance liquid chromatography with fluorescence detection. ( Beijnen, JH; Hoetelmans, RM; Lange, JM; Meenhorst, PL; Mulder, JW; van Heeswijk, RP; Veldkamp, AI, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Veldkamp, AI | 1 |
| van Heeswijk, RP | 1 |
| Hoetelmans, RM | 1 |
| Meenhorst, PL | 1 |
| Mulder, JW | 1 |
| Lange, JM | 1 |
| Beijnen, JH | 1 |
| Villani, P | 1 |
| Feroggio, M | 1 |
| Gianelli, L | 1 |
| Bartoli, A | 1 |
| Montagna, M | 1 |
| Maserati, R | 1 |
| Regazzi, MB | 1 |
| Cheng, CL | 1 |
| Chou, CH | 1 |
| Hu, OY | 1 |
| Rezk, NL | 1 |
| Tidwell, RR | 1 |
| Kashuba, AD | 1 |
4 other studies available for delavirdine and Sensitivity and Specificity
| Article | Year |
|---|---|
Rapid quantification of delavirdine, a novel non-nucleoside reverse transcriptase inhibitor, in human plasma using isocratic reversed-phase high-performance liquid chromatography with fluorescence detection.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Delavirdine; Drug Monitoring; HIV Infections; | 1999 |
Antiretrovirals: simultaneous determination of five protease inhibitors and three nonnucleoside transcriptase inhibitors in human plasma by a rapid high-performance liquid chromatography--mass spectrometry assay.
Topics: Alkynes; Benzoxazines; Carbamates; Chromatography, Liquid; Cyclopropanes; Delavirdine; Drug Monitori | 2001 |
Determination of delavirdine in very small volumes of plasma by high-performance liquid chromatography with fluorescence detection.
Topics: Calibration; Chromatography, High Pressure Liquid; Delavirdine; Reference Standards; Reproducibility | 2002 |
Simple and rapid quantification of the non-nucleoside reverse transcriptase inhibitors nevirapine, delavirdine, and efavirenz in human blood plasma using high-performance liquid chromatography with ultraviolet absorbance detection.
Topics: Alkynes; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Delavirdine; HIV Infecti | 2002 |