Bromodomain adjacent to zinc finger domain protein 2B

A bromodomain adjacent to zinc finger domain protein 2B that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9UIF8]

hWALp4

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
n-methylpyrrolidone	Homo sapiens (human)	IC50	34,000.0000	1	1
ro 22-3581	Homo sapiens (human)	IC50	826.0000	1	1
N1-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide	Homo sapiens (human)	IC50	476.0000	1	1
i-bet726	Homo sapiens (human)	IC50	31.6228	1	1

This protein enables 3 target(s):

Target	Category	Definition
DNA binding	molecular function	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
metal ion binding	molecular function	Binding to a metal ion. [GOC:ai]

This protein is located in 1 target(s):

Target	Category	Definition
nucleus	cellular component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]

This protein is part of 1 target(s):

Target	Category	Definition
chromatin	cellular component	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130]

This protein is involved in 2 target(s):

Target	Category	Definition
chromatin remodeling	biological process	A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. [GOC:jid, GOC:vw, PMID:12042764, PMID:12697820]
regulation of transcription by RNA polymerase II	biological process	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]