Page last updated: 2024-08-07 13:17:56
Thymidylate synthase
A thymidylate synthase that is encoded in the genome of rat. [OMA:P45352, PRO:DNx]
Synonyms
TS;
TSase;
EC 2.1.1.45
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| raltitrexed | Rattus norvegicus (Norway rat) | IC50 | 0.9000 | 1 | 1 |
| n-(4(n-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid | Rattus norvegicus (Norway rat) | IC50 | 0.3600 | 1 | 1 |
| pemetrexed | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 1 | 1 |
| cb 3717 | Rattus norvegicus (Norway rat) | IC50 | 0.3600 | 1 | 1 |