A protein that is a translation product of the AKR1B1 gene in pig. [PRO:DNx, UniProtKB:P80276]
EC 1.1.1.300;
EC 1.1.1.372;
EC 1.1.1.54;
Aldehyde reductase;
Aldose reductase;
AR;
1.1.1.21
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ponalrestat | Sus scrofa (pig) | IC50 | 0.0210 | 1 | 1 |
| 4-Anilino-4-oxobutanoic acid | Sus scrofa (pig) | IC50 | 192.0000 | 1 | 1 |
| tolrestat | Sus scrofa (pig) | IC50 | 5.3483 | 3 | 3 |
| lemax | Sus scrofa (pig) | IC50 | 227.0000 | 1 | 1 |
| n-acetyltyramine | Sus scrofa (pig) | IC50 | 160.0000 | 1 | 1 |
| as 3201 | Sus scrofa (pig) | IC50 | 0.0150 | 1 | 1 |
| fidarestat | Sus scrofa (pig) | IC50 | 2.5000 | 1 | 1 |
| sorbinil | Sus scrofa (pig) | IC50 | 1.1000 | 1 | 1 |
| quercetin | Sus scrofa (pig) | IC50 | 50.1000 | 1 | 1 |
| quercetin 3-o-glucopyranoside | Sus scrofa (pig) | IC50 | 16.0000 | 1 | 1 |
| 3-methylquercetin | Sus scrofa (pig) | IC50 | 95.0000 | 1 | 1 |
| rhamnazin | Sus scrofa (pig) | IC50 | 91.0000 | 1 | 1 |