Page last updated: 2024-11-10

rutin sulfate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

rutin sulfate: RN refers to Na salt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5284453
MeSH IDM0157444

Synonyms (6)

Synonym
rutin sulfate
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranoside - sulfuric acid (1:1)
12768-44-4
DTXSID1021249
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one;sulfuric acid
rutinsulfate

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" The oral bioavailability of monoHER is <1%."( Stability of monoHER in an aqueous formulation for i.v. administration.
Abou El Hassan, MA; Bast, A; Touw, DJ; van der Vijgh, WJ; Wilhelm, AJ, 2000
)
0.31

Dosage Studied

ExcerptRelevanceReference
" At the same time, the peripheral venous resistance decreases in a dose-response relationship."( Effect of a combination of coumarin derivatives and rutoside on venous and lymphatic circulations during severe constriction of the caudal vena cava in rabbits.
Angignard, J; Borzeix, MG; Dedieu, F; Dupont, JM; Leutenegger, E; Miloradovich, T, 1995
)
0.29
"This paper describes a validated high-performance liquid chromatographic (HPLC) - photodiode array (PDA) detection method to quantitate five flavonol components as markers; rutin, quercitrin, quercetin, kaempferol and isorhamnetin for use in the quality control of Ginkgo biloba dosage forms."( High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms.
Dubber, MJ; Kanfer, I, 2004
)
0.32
"A suitable method was developed to identify and quantitate five relevant flavonol marker compounds and was successfully used to assay some commercially available solid oral dosage forms of Ginkgo biloba ."( High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms.
Dubber, MJ; Kanfer, I, 2004
)
0.32
" The relationship of dose and AUC of RDS was linear within the dosage range."( Pharmacokinetics and plasma protein binding of rutin deca (H-) sulfate sodium.
Lu, SJ; Wang, XJ; Yao, TW; Zeng, S, 2009
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (27)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (3.70)18.7374
1990's10 (37.04)18.2507
2000's15 (55.56)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.21 (24.57)
Research Supply Index3.61 (2.92)
Research Growth Index5.64 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.21)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials5 (16.13%)5.53%
Reviews3 (9.68%)6.00%
Case Studies2 (6.45%)4.05%
Observational0 (0.00%)0.25%
Other21 (67.74%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]