2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid is a chemical compound also known as **2,4-dichlorophenoxyacetic acid (2,4-D)**. It's a widely used **herbicide** and is **not** a propionic acid derivative.
Here's why it's important for research:
* **Agriculture:** 2,4-D is one of the most widely used herbicides globally. It's crucial for controlling broadleaf weeds in various crops, including cereals, soybeans, and cotton. Research focuses on:
* **Improving its efficacy:** Studies explore ways to enhance its weed control capabilities and reduce application rates for environmental sustainability.
* **Understanding its mode of action:** Scientists investigate how 2,4-D disrupts plant growth to develop new and more targeted herbicides.
* **Developing resistant crops:** Research aims to create crops that are tolerant to 2,4-D, allowing for more efficient weed management without harming the desired plants.
* **Environmental impact:** 2,4-D has been associated with some environmental concerns, including potential impacts on water quality and non-target organisms. Research focuses on:
* **Minimizing its environmental footprint:** Studies explore alternative formulations and application methods to reduce environmental risks.
* **Assessing its long-term effects:** Researchers investigate the persistence of 2,4-D in the environment and its potential for bioaccumulation.
* **Human health:** 2,4-D is considered relatively safe for human use at recommended application rates. However, research continues to investigate potential health risks, particularly long-term exposure.
**It's important to note that 2,4-D is a powerful chemical and should only be used according to label instructions and safety guidelines.**
**In summary, 2,4-D is an important research subject due to its widespread use in agriculture, its environmental implications, and ongoing efforts to understand its potential human health impacts.**
2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid: an herbicide; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
diclofop : A racemate composed of equimolar amounts of (R)- and (S)-diclofop. It is a metabolite of declofop-methyl and a postemergence herbicide used for the control of wild oats and annual weeds in wheat, barley, rye and broad-leaved crops. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid : An aromatic ether that is 2-(4-hydroxyphenoxy)propanoic acid in which the hydrogen of the hydroxy group at position 4 has been substituted by a 2,4-dichlorophenyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
ID Source | ID |
---|---|
PubMed CID | 38687 |
CHEMBL ID | 2288781 |
CHEBI ID | 145406 |
CHEBI ID | 81909 |
SCHEMBL ID | 66474 |
MeSH ID | M0522792 |
Synonym |
---|
diclofop |
methyl 2-(4-(2,4-dichlorophenyoxy)phenoxy)propanoate |
brn 2338390 |
hoe 21079 |
diclofop acid |
diclofop [ansi:bsi:iso] |
2-(4-(2,4-dichlorophenoxy)phenoxy)propanoic acid |
(rs)-2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid |
caswell no. 328b |
dichlorfop acid |
propanoic acid, 2-(4-(2,4-dichlorophenoxy)phenoxy)- |
2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid |
NCGC00164481-01 |
FT-0639674 |
CHEBI:145406 |
40843-25-2 |
C18716 |
unii-3ln56779kt |
3ln56779kt , |
diclofop, (+/-)- |
hoe-21079 |
2-(4-(2',4'-dichlorophenoxy)phenoxy)propionic acid |
(+/-)-diclofop |
diclofop [iso] |
SCHEMBL66474 |
CHEMBL2288781 |
chebi:81909 |
2-[4'-(2,4-dichlorophenoxy)-phenoxy]-propionic acid |
2-[4'-(2,4-dichlorophenoxy)-phenoxy]propionic acid |
4-(2',4'-dichlorophenoxy)-alpha-phenoxy-propionic acid |
AKOS024354406 |
2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid # |
DTXSID5041859 |
mfcd00152216 |
(+/-)-diclofop, analytical standard |
hoe-021079 |
diclofop (free acid) |
Q27155655 |
AMY14561 |
diclofop (free acid) 100 microg/ml in acetonitrile |
2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid |
1ST22082 |
Class | Description |
---|---|
aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
dichlorobenzene | Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions. |
monocarboxylic acid | An oxoacid containing a single carboxy group. |
diether | A polyether in which the number of ether linkages is 2. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (18.18) | 29.6817 |
2010's | 9 (81.82) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.38) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 11 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |