| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
2,3-dihydroxybenzoic acid
2,3-dihydroxybenzoic acid: RN given refers to parent cpd. dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.. 2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta. | 2.95 | 4 | 0 | dihydroxybenzoic acid | human xenobiotic metabolite;
plant metabolite |
adenine
[no description available] | 2.15 | 1 | 0 | 6-aminopurines;
purine nucleobase | Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
benzoic acid
Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.. benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.. aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring. | 2.15 | 1 | 0 | benzoic acids | algal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite |
catechol
[no description available] | 2.17 | 1 | 0 | catechols | allelochemical;
genotoxin;
plant metabolite |
glycine
[no description available] | 2.03 | 1 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
deferoxamine
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.. desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator. | 2.31 | 1 | 0 | acyclic desferrioxamine | bacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore |
serine
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.. serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. | 2.01 | 1 | 0 | L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
lysine
Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine. | 2.31 | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
adenosine monophosphate
Adenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. | 2.41 | 2 | 0 | adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate | adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical |
ornithine
Ornithine: An amino acid produced in the urea cycle by the splitting off of urea from arginine.. ornithine : An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5. | 2.07 | 1 | 0 | non-proteinogenic L-alpha-amino acid;
ornithine | algal metabolite;
hepatoprotective agent;
mouse metabolite |
tetrahydrofuran
oxolane : A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen. | 2.13 | 1 | 0 | cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound | polar aprotic solvent |
diethylenetriamine
diethylenetriamine: RN given refers to parent cpd | 2.13 | 1 | 0 | polyazaalkane;
triamine | |
ethyl acetate
ethyl acetate : The acetate ester formed between acetic acid and ethanol. | 2.6 | 1 | 0 | acetate ester;
ethyl ester;
volatile organic compound | EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
metabolite;
polar aprotic solvent;
Saccharomyces cerevisiae metabolite |
selenomethionine
[no description available] | 2.08 | 1 | 0 | selenoamino acid;
selenomethionines | plant metabolite |
paraquat
Paraquat: A poisonous dipyridilium compound used as contact herbicide. Contact with concentrated solutions causes irritation of the skin, cracking and shedding of the nails, and delayed healing of cuts and wounds.. paraquat : An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions. | 2.45 | 2 | 0 | organic cation | geroprotector;
herbicide |
enterobactin
[no description available] | 4.12 | 15 | 0 | catechols;
crown compound;
macrotriolide;
polyphenol | bacterial metabolite;
siderophore |
ferric citrate
ferric citrate: RN given refers to Fe(+3)[1:1] salt. iron(III) citrate : An iron chelate resulting from the combination of iron(3+) and citrate(3-). | 2.15 | 1 | 0 | iron chelate | anti-anaemic agent;
nutraceutical |
surfactin peptide
surfactin peptide: antineoplastic product isolated from Bacillus sp. | 2.05 | 1 | 0 | | |
1-hydroxy-2(1h)-pyridinone
1-hydroxy-2(1H)-pyridinone: structure in first source | 2.13 | 1 | 0 | | |
tris(2-aminoethyl)amine
tris(2-aminoethyl)amine: structure given in first source | 2.03 | 1 | 0 | tetramine | |
1,4,7-triazacyclononane
1,4,7-triazacyclononane: structure given in first source | 2.13 | 1 | 0 | azacycloalkane;
crown amine;
saturated organic heteromonocyclic parent | |
rhizoferrin
rhizoferrin: a ferric polycarboxylate; a complexone-type siderophore; synthesized and secreted by Rhizopus microsporus | 2.07 | 1 | 0 | | |
fengycin
fengycin: lipopeptide from Bacillus subtilis | 4.14 | 4 | 0 | cyclodepsipeptide | |
bacillomycin d
bacillomycin D: from strain of Bacillus subtilis; contains lipid moiety which is mixture of 3-amino-12-methyltridecanoic acid (40%) & 3-amino-12-methyltetradecanoic acid (60%) & peptide moiety: L-Asp(1), L-Glu(1), L-Pro(1), D-Ser(1), L-Thr(1) & D-Tyr(1); two moieties joined by threonyl beta-aminoacid linkage; see also bacillomycin L & bacillomycin S | 3.69 | 2 | 0 | | |
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 2.15 | 1 | 0 | cysteinium | fundamental metabolite |
difficidin
difficidin: isolated from Bacillus subtilis; structure given in first source | 2.05 | 1 | 0 | | |
bacilysin
bacilysin: structure. bacilysin : A non-ribosomally synthesised dipeptide that consists of L-alanyl and anticapsin units linked by a peptide bond. | 2.89 | 3 | 0 | | |
macrolactin a
macrolactin A: a 24-membered macrolide; structure in first source | 2.05 | 1 | 0 | | |
petrobactin
petrobactin: a photoreactive siderophore produced by the oil-degrading marine bacterium; structure in first source | 3.43 | 7 | 0 | | |
myxochelin a
myxochelin A: structure given in first source; catechole siderophore isolated from Angiococcus disciformis | 2.31 | 1 | 0 | | |
bacillaene
bacillaene: an inhibitor of procaryotic protein synthesis; produced by the PksX megacomplex; isolated from Bacillus subtilis; a hexaene with molecular formula C35-H48-O7. bacillaene : A polyene antibiotic obtained from Bacillus subtilis 168 that is active against a broad spectrum of bacteria. It is notoriously unstable. | 2.48 | 2 | 0 | enamine;
monocarboxylic acid amide;
polyene antibiotic;
polyketide;
secondary alcohol | antibacterial agent;
antimicrobial agent;
bacterial metabolite |
staphyloferrin a
staphyloferrin A: from Staphylococcus hyicus DSM 20459; structure given in first source; has siderophore activity. staphyloferrin A : A D-ornithine derivative obtained by formal condensation of the terminal carboxy groups of two citric acid units with the two amino groups of D-ornithine. | 2.07 | 1 | 0 | D-ornithine derivative;
pentacarboxylic acid;
tertiary alcohol;
tricarboxylic acid amide | bacterial metabolite;
siderophore |
chrome azurol s
chrome azurol S: reagent for beryllium determination spectrophotometrically | 2 | 1 | 0 | | |