Compounds > trifluoperazine
Page last updated: 2024-09-20

trifluoperazine

Cross-References

ID SourceID
PubMed CID5566
CHEMBL ID422
CHEBI ID45951
SCHEMBL ID24866
MeSH IDM0021955

Synonyms (201)

Synonym
nsc-17474
smr001566649
BIDD:PXR0132
AB00053558-27
BRD-K89732114-300-05-5
BRD-K89732114-001-02-6
BRD-K89732114-001-03-4
gtpl214
nsc-46061
DIVK1C_000843
KBIO1_000843
NCI60_004087
NCI60_001427
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride
SPECTRUM_000668
BIOMOL-NT_000060
PDSP1_001300
ccris 6994
nsc 17474
trifluoperazina [italian]
phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-
nsc 46061
2-trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine
trifluoperazinum [inn-latin]
10h-phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-
trifluoperazine [inn:ban]
trifluoperazina [inn-spanish]
einecs 204-219-4
hsdb 3195
trifluoperazin
10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10h-phenothiazine
10-[3-(4-methyl-piperazin-1-yl)-propyl]-2-trifluoromethyl-10h-phenothiazine
10h-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
lopac-t-8516
BIO2_000915
BIO1_001436
cas-440-17-5
NCGC00013226-02
BIO2_000435
BIO1_000458
BIO1_000947
NCGC00013226-03
IDI1_002190
LOPAC0_001232
BPBIO1_000338
TFP ,
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10h-phenothiazine
stelazine (*dihydrochloride*)
NCGC00013226
BSPBIO_002928
PRESTWICK3_000313
IDI1_000843
PRESTWICK2_000313
QTL1_000085
CMAP_000048
BSPBIO_001190
SPECTRUM5_001553
BPBIO1_001345
rp 7623
triflurin
trifluperazine
triperazine
trifluoromethylperazine
trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
trifluoroperazine
10-(gamma-(n'-methylpiperazino)propyl)-2-trifluoromethylphenothiazine
flurazine
10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazine
AB00053558
trifluoperazine ,
C07168
117-89-5
trifluoperazinum
CHEBI:45951 ,
trifluoperazina
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10h-phenothiazine
DB00831
NCI17474 ,
NCGC00024251-06
NCGC00024251-05
STK182873
KBIO2_000530
KBIOSS_002437
KBIO2_006284
KBIOSS_001148
KBIOGR_002431
KBIO2_002431
KBIO3_002148
KBIO3_002910
KBIOGR_000530
KBIO3_000960
KBIO2_001148
KBIO3_000959
KBIO2_007567
KBIOGR_000835
KBIO2_003098
KBIO2_004999
KBIO2_003716
KBIO2_005666
KBIOSS_000530
PRESTWICK1_000313
SPECTRUM2_000828
SPECTRUM4_000368
SPBIO_002525
NCISTRUC1_001127
SPBIO_000755
SPECTRUM3_001374
NCISTRUC2_001093
NINDS_000843
PRESTWICK0_000313
PDSP2_001284
BSPBIO_000306
NCGC00024251-03
NCGC00024251-04
NCGC00013226-04
NCGC00024251-07
apo-trifluoperazine
SR-01000003020-6
HMS2089J11
HMS1990L11
NCGC00013226-12
AKOS001487920
L001075
rp-7623
CHEMBL422
trifluoperazine (inn)
D08636
apo-trifluoperazine (tn)
HMS1792L11
HMS1362L11
FT-0650159
214izi85k3 ,
unii-214izi85k3
ksc-210-031
KUC109776N
CCG-37306
NCGC00013226-05
NCGC00013226-09
NCGC00013226-10
NCGC00013226-06
NCGC00013226-08
NCGC00013226-07
NCGC00013226-13
NCGC00013226-11
stellazine
trifluroperizine
NCGC00013226-15
S5856
trifluoperazine [mi]
trifluoperazine [hsdb]
trifluoperazine [who-dd]
trifluoperazine [vandf]
trifluoperazine [inn]
SCHEMBL24866
10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride
cid_2913535
10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride
bdbm79181
cid_5566
DTXSID1046928
MLS006011857
10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10h-phenothiazine #
triftazin (salt/mix)
fluoperazine (salt/mix)
triftazine (salt/mix)
synklor (salt/mix)
triphthazine (salt/mix)
10-(.gamma.-(n'-methylpiperazino)propyl)-2-trifluoromethylphenothiozine
2-trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine
jatroneural (salt/mix)
terfluzine (salt/mix)
stelazine (salt/mix)
phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10h-phenothiazine
HMS3429O07
AB00053558_29
AB00053558_28
81498-90-0
SBI-0051199.P003
MRF-0000088
2-(((4-chlorophenyl)sulfonyl)amino)-benzoicaci
1432064-02-2
Q1752915
BRD-K89732114-300-07-1
BRD-K89732114-001-05-9
EX-A3330
SDCCGSBI-0051199.P005
BCP32898
triphthazine;trifluperazine;nsc-17474;rp-7623;skf-5019
NCGC00013226-26
AC-35814
EN300-708763
10h-phenothiazine,10-[3-[4-(methyl-d3)-1-piperazinyl]propyl]-2-(trifluoromethyl)-
n05ab06
10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)phenothiazine
trifluoperazinum (inn-latin)
trifluoperazina (inn-spanish)
10-(3-(4-methyl-piperazin-1-yl)-propyl)-2-trifluoromethyl-10h-phenothiazine
2-trifluoromethyl-10-

Research Excerpts

Overview

ExcerptReference
"Trifluoperazine (TFP) is a clinical drug for acute and chronic psychosis therapy."( Chen, J; Chen, X; Chen, Y; Jing, Z; Li, A; Yu, W, 2022)
"Trifluoperazine (TFP) is a typical antipsychotic primarily used to treat schizophrenia. "( Hsu, YB; Lan, MC; Lan, MY; Lee, WY; Yeh, CF; Yu, TH, 2023)
"Trifluoperazine is a compound that binds troponin, and other components of the calcium pathway, which impacts calcium regulation of contraction."( Dawson, JF; Jones, MR; Prill, K; Steffensen, K; Teng, GZ, 2023)
"Trifluoperazine (TFP) is a therapeutic agent for the treatment of psychiatric disorders that reduces edema of the central nervous system."( Cheng, J; Li, S; Ma, H; Xing, R; Yu, J; Zhao, Y, 2023)
"Trifluoperazine is a potent antipsychotic drug used in the treatment of neurological disorders. "( Mahanty, S; Raghav, D; Rathinasamy, K, 2020)
"Trifluoperazine (TFP), which is an antipsychotic drug, has the ability to bind to NUPR1 and mimic NUPR1 deficiency in cancer cells."( Cui, B; Li, Y; Liu, Z; Ma, J; Ma, Z; Sun, Y; Yan, X; Yang, J; Yin, Y; Zhang, Y; Zhou, R, 2020)
"Trifluoperazine (TFP) is an approved antipsychotic drug with good bioavailability in brain and had shown anticancer effect in several types of cancer."( Feng, Z; Gao, T; Hu, X; Lei, Q; Peng, C; Ran, Z; Wang, Q; Wang, R; Xia, Y; Xie, Z; Xu, F; Xue, Q; Yang, N; Yang, Y; Yu, L; Zeng, Z, 2018)
"Trifluoperazine is a long-established high potency typical antipsychotic drug used in the treatment of schizophrenia and schizophrenia-like illnesses."( Adams, CE; Furtado, VA; Haynes, E; Koch, K; Mansi, K; Sampson, S, 2014)
"Trifluoperazine is a phenothiazine derivative which is mainly used in the management of schizophrenia and also acts as a calmodulin inhibitor. "( Choi, JS; Hahn, SJ; Kim, DH; Lee, SJ, 2016)
"Trifluoperazine was found to be a non-substrate inhibitor for human UGT2B10."( Grimm, SW; Guo, J; Zhou, D, 2011)
"Trifluoperazine is an inexpensive accessible 'high potency' antipsychotic drug, widely used to treat schizophrenia or related psychoses."( Lima, MS; Marques, LO; Soares, BG, 2004)
"Trifluoperazine (TFP) is a phenothiazine capable of inhibiting lymphocyte proliferation as well as natural killer cells (NK) and lymphokine-activated killer cells (LAK) cytotoxic activity. "( Harab, RC; Pires, V; Rumjanek, VM, 1996)
"Trifluoperazine (TFP) is a potent antipsychotic agent, dibucaine (DBC) is a local anaesthetic and praziquantel (PZQ) is a highly effective agent against schistosomiasis. "( Brites, D; Brito, MA; Malheiros, SV; Meirelles, NC, 2000)
"Trifluoperazine is a potent inhibitor of the carrier in mitoplasts but not in mitochondria."( Crompton, M; Hayat, LH, 1985)
"Trifluoperazine (TFP) is a potent, competitive inhibitor of the calcium-calmodulin complex."( Alexander, RW; MacLellan, DG; Saydjari, R; Thompson, JC; Townsend, CM, 1988)

Effects

ExcerptReference
"Trifluoperazine has a dual effect on the Ca2+ pump of brain microsomes."( de Meis, L; Rocha, JB; Souza, DO; Wolosker, H, 1996)
"Trifluoperazine (TFP) has been reported to inhibit the proliferation of several types of cancer cell, however, the effects of TFP in renal proliferation diseases remain to be fully elucidated."( Li, R; Luo, Y; Wang, B; Zhou, X, 2018)
"Trifluoperazine has a dual effect on the Ca2+ pump of brain microsomes."( de Meis, L; Rocha, JB; Souza, DO; Wolosker, H, 1996)
"Trifluoperazine (TFP) has been widely studied in relation to its mode of binding and its inactivation of calmodulin (CaM). "( Hirono, S; Suga, M; Yamaotsu, N, 2001)

Actions

ExcerptReference
"Trifluoperazine did not increase cell 45Ca2+ with or without A23187."( Lee, JW; Vidaver, GA, 1984)
"Trifluoperazine seems to inhibit calcium uptake by uncoupling the linkage between calcium uptake by uncoupling the linkage between cholinergic receptor stimulation and calcium channel activation."( Izumi, F; Kobayashi, H; Sakurai, S; Wada, A; Yanagihara, N, 1983)
"Trifluoperazine can thus inhibit calmodulin-independent reactions particularly when used at high concentrations."( Cheah, KS; Waring, JC, 1983)
"Trifluoperazine does not inhibit exercise induced increases in glucose uptake; therefore, the mechanisms by which insulin and functional activity increase glucose uptake are different."( Favier, C; Gorostiza, P; Guarner, V; Hernández, E; Huerto, R; Valenzuela, F, 1994)
"Trifluoperazine (TFP) could inhibit the proliferation of A549 lung cancer cells and human embryo lung (HEL) cells. "( Fan, X, 1992)
"Trifluoperazine did not enhance the depressant actions of the uptake resistant analog, adenosine 5'-N-ethylcarboxamide."( Phillis, JW, 1985)
"Trifluoperazine causes an increase of the amplitude of maximum (h max) of RP and a prolongation of the time of half decrease (t2)."( Cai, HR; Stieve, H, 1986)

Treatment

ExcerptReference
"Both trifluoperazine treatment and ConA treatment increased the steady-state levels of MT1-MMP mRNA and proMMP-2 mRNA."( Ito, A; Mori, Y; Nagase, H; Sanekata, K; Sato, H; Sato, T; Seiki, M; Yamada, M, 1998)
"Both trifluoperazine and W-7 pretreatment significantly inhibited the effect of a cyclic AMP analogue to increase rabbit cortical collecting tubule Lp."( Dillingham, MA; Dixon, BS; Kim, JK; Wilson, PD, 1986)
"Treatment with trifluoperazine (TFP) (which can act as a calmodulin antagonist and Ca2+-ATPase inhibitor), at a low concentration that precluded nonspecific K+ efflux, increased intracellular Sr2+ accumulation by approximately 3.6- and 1.4-fold in unsupplemented and 18:2-supplemented cells, respectively."( Avery, SV; Ghazi, AM; Hoptroff, MJ; Smith, SL, 1999)
"Upon treatment with trifluoperazine (TFP), the redistribution of both MLCK and insulin receptors are inhibited concomitantly."( Bourguignon, LY; Majercik, MH, 1985)

Roles (6)

RoleDescription
phenothiazine antipsychotic drugnull
dopaminergic antagonistA drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antiemeticA drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitorAn EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitorAn EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5).
calmodulin antagonistAn antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
phenothiazines
organofluorine compoundAn organofluorine compound is a compound containing at least one carbon-fluorine bond.
N-alkylpiperazine
N-methylpiperazine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

trifluoperazine is involved in 1 pathway(s), involving a total of 24 unique proteins and 15 unique compounds

PathwayProteinsCompounds
Regucalcin in proximal tubule epithelial kidney cells2415

Protein Targets (108)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, HADH2 proteinHomo sapiens (human)Potency0.19950.025120.237639.8107AID886
Chain B, HADH2 proteinHomo sapiens (human)Potency0.19950.025120.237639.8107AID886
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency15.84890.631035.7641100.0000AID504339
glp-1 receptor, partialHomo sapiens (human)Potency8.91250.01846.806014.1254AID624417
15-lipoxygenase, partialHomo sapiens (human)Potency19.95260.012610.691788.5700AID887
phosphopantetheinyl transferaseBacillus subtilisPotency44.10730.141337.9142100.0000AID1490
ATAD5 protein, partialHomo sapiens (human)Potency17.76490.004110.890331.5287AID493106; AID493107
USP1 protein, partialHomo sapiens (human)Potency48.62680.031637.5844354.8130AID504865; AID540327
NFKB1 protein, partialHomo sapiens (human)Potency11.22020.02827.055915.8489AID895; AID928
TDP1 proteinHomo sapiens (human)Potency9.51230.000811.382244.6684AID686978; AID686979
Microtubule-associated protein tauHomo sapiens (human)Potency40.07490.180013.557439.8107AID1460
ThrombopoietinHomo sapiens (human)Potency15.84890.02517.304831.6228AID917; AID918
Smad3Homo sapiens (human)Potency35.48130.00527.809829.0929AID588855
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency11.22020.707912.194339.8107AID720542
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.81070.011212.4002100.0000AID1030
thyroid stimulating hormone receptorHomo sapiens (human)Potency31.62280.001318.074339.8107AID926
regulator of G-protein signaling 4Homo sapiens (human)Potency18.88760.531815.435837.6858AID504845
EWS/FLI fusion proteinHomo sapiens (human)Potency14.82100.001310.157742.8575AID1259252; AID1259253; AID1259255; AID1259256
67.9K proteinVaccinia virusPotency15.91090.00018.4406100.0000AID720579; AID720580
glucocerebrosidaseHomo sapiens (human)Potency25.11890.01268.156944.6684AID2101
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency17.91620.035520.977089.1251AID504332
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency52.11940.016525.307841.3999AID602332
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency1.10380.00207.533739.8107AID891
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency58.04790.01262.451825.0177AID485313
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency17.90080.316212.443531.6228AID902; AID924
cytochrome P450 2C19 precursorHomo sapiens (human)Potency7.50930.00255.840031.6228AID899
D(1A) dopamine receptorHomo sapiens (human)Potency0.51060.02245.944922.3872AID488982; AID488983
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency56.23410.354828.065989.1251AID504847
chromobox protein homolog 1Homo sapiens (human)Potency55.52780.006026.168889.1251AID488953; AID540317
mitogen-activated protein kinase 1Homo sapiens (human)Potency25.11890.039816.784239.8107AID995
atrial natriuretic peptide receptor 2 precursorHomo sapiens (human)Potency16.48160.00669.809418.4927AID1347050
ras-related protein Rab-9AHomo sapiens (human)Potency58.04790.00022.621531.4954AID485297
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency15.88410.00378.618923.2809AID2660; AID2666; AID2668
gemininHomo sapiens (human)Potency26.27030.004611.374133.4983AID624296; AID624297
DNA polymerase kappa isoform 1Homo sapiens (human)Potency18.88760.031622.3146100.0000AID588579
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency18.10560.005612.367736.1254AID624032
survival motor neuron protein isoform dHomo sapiens (human)Potency31.62280.125912.234435.4813AID1458
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency13.50930.031610.279239.8107AID884; AID885
M-phase phosphoprotein 8Homo sapiens (human)Potency37.68580.177824.735279.4328AID488949
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency15.84890.251215.843239.8107AID504327
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)Potency22.38720.058010.694926.6086AID602310
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency10.00000.00106.000935.4813AID943; AID944
lethal factor (plasmid)Bacillus anthracis str. A2012Potency17.55950.020010.786931.6228AID912
lamin isoform A-delta10Homo sapiens (human)Potency11.22020.891312.067628.1838AID1487
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency12.58930.316212.765731.6228AID881
Glycoprotein hormones alpha chainHomo sapiens (human)Potency14.12544.46688.344810.0000AID624291
Integrin beta-3Homo sapiens (human)Potency19.95260.316211.415731.6228AID924
Integrin alpha-IIbHomo sapiens (human)Potency19.95260.316211.415731.6228AID924
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency12.58930.00638.235039.8107AID881
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Guanine nucleotide-binding protein GHomo sapiens (human)Potency25.11891.995325.532750.1187AID624287
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency1.41251.000010.475628.1838AID1457
GABA theta subunitRattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
Ataxin-2Homo sapiens (human)Potency17.78280.011912.222168.7989AID588378
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency13.89931.000012.224831.6228AID885
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Genome polyprotein IC50 (µMol)0.70000.70001.95673.8000AID241445
NADPH oxidase 1Homo sapiens (human)IC50 (µMol)17.00000.04401.26095.5000AID2808
Ubiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)IC50 (µMol)8.00002.00005.61258.0000AID1315765
Bile salt export pumpHomo sapiens (human)IC50 (µMol)10.00000.11007.190310.0000AID1443987; AID1449628
Lysozyme C-1Rattus norvegicus (Norway rat)IC50 (µMol)9.00009.00009.35009.7000AID102993
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC50 (µMol)45.00000.00022.81679.0000AID1605053
Protein kinase C alpha typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.21931.0000AID165122
Beta-glucuronidaseRattus norvegicus (Norway rat)IC50 (µMol)7.80002.80005.50007.8000AID40449
ATP-dependent translocase ABCB1Homo sapiens (human)IC50 (µMol)8.13330.00022.318510.0000AID681126; AID681127; AID681131
ATP-dependent translocase ABCB1Homo sapiens (human)Ki6.50000.02002.35948.5900AID150616
Protein kinase C delta typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.25851.0000AID165122
Protein kinase C epsilon typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.25851.0000AID165122
Protein kinase C zeta typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.25851.0000AID165122
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)IC50 (µMol)6.22600.00001.612910.0000AID625171
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)Ki5.10080.00042.03378.6606AID625171
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC50 (µMol)0.35000.00021.874210.0000AID36847
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)IC50 (µMol)0.35000.00021.270410.0000AID36847
Trypanothione reductaseTrypanosoma cruziIC50 (µMol)72.00005.80005.80005.8000AID214488
Trypanothione reductaseTrypanosoma cruziKi23.00000.07605.15297.6000AID214654
C-8 sterol isomeraseSaccharomyces cerevisiae S288CKi0.50000.00000.90487.1500AID239296
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288CIC50 (µMol)1.40001.30003.37279.6000AID581672
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC50 (µMol)0.35000.00001.819410.0000AID36847
D(2) dopamine receptorRattus norvegicus (Norway rat)IC50 (µMol)0.01600.00010.54948.4000AID61326
Protein kinase C gamma typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.26401.1000AID165122
Protein kinase C beta typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.21641.1000AID165122
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)IC50 (µMol)100.00000.00051.350010.0000AID705447
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC50 (µMol)6.22600.00091.901410.0000AID625171
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)Ki5.10080.00211.840710.0000AID625171
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)Ki0.00800.00040.54906.7000AID239597
Protein kinase C eta typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.25851.0000AID165122
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)IC50 (µMol)6.22600.10482.83988.3173AID625171
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)Ki5.10080.08582.95428.6606AID625171
WD repeat-containing protein 48Homo sapiens (human)IC50 (µMol)8.00002.00006.31678.0000AID1315765
Sigma non-opioid intracellular receptor 1Homo sapiens (human)Ki0.01500.00000.490110.0000AID239347
Emopamil-binding protein-likeHomo sapiens (human)Ki0.00390.00280.00330.0039AID723649
Protein kinase C theta typeRattus norvegicus (Norway rat)IC50 (µMol)500.00000.00000.25851.0000AID165122
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AlbuminRattus norvegicus (Norway rat)Kd14.00001.47006.53179.3100AID1215123
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)Kd0.00100.00042.58328.5114AID4848
Calmodulin-1Homo sapiens (human)Kd1.00001.00001.12001.2400AID404335
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)Kd0.00100.00012.62198.5114AID4848
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)Kd0.00100.00042.47358.5114AID4848
D(2) dopamine receptorRattus norvegicus (Norway rat)Kd0.00050.00030.81836.7000AID61331
Calmodulin Bos taurus (cattle)Kd3.40001.80002.93333.5000AID1297606
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Snq2pSaccharomyces cerevisiae EC1118INH6.90003.20006.26008.8000AID581808
DNA repair protein RAD52 homolog isoform aHomo sapiens (human)AC5013.00000.150012.066235.2100AID652116
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288CINH8.30004.20006.18338.3000AID581806
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (279)

Processvia Protein(s)Taxonomy
lipid metabolic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
phospholipid metabolic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
apoptotic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
negative regulation of cell population proliferationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
positive regulation of macrophage derived foam cell differentiationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
arachidonic acid metabolic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
negative regulation of cell migrationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
prostate gland developmentPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
regulation of epithelial cell differentiationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
positive regulation of chemokine productionPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
positive regulation of peroxisome proliferator activated receptor signaling pathwayPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
positive regulation of keratinocyte differentiationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
negative regulation of cell cyclePolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
negative regulation of growthPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
hepoxilin biosynthetic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
endocannabinoid signaling pathwayPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
cannabinoid biosynthetic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
lipoxin A4 biosynthetic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
linoleic acid metabolic processPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
lipid oxidationPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
lipoxygenase pathwayPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
skeletal system developmentUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
DNA repairUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
regulation of DNA repairUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
proteolysisUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
response to UVUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
protein deubiquitinationUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
monoubiquitinated protein deubiquitinationUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STATUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
positive regulation of error-prone translesion synthesisUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
fatty acid metabolic processBile salt export pumpHomo sapiens (human)
bile acid biosynthetic processBile salt export pumpHomo sapiens (human)
xenobiotic metabolic processBile salt export pumpHomo sapiens (human)
xenobiotic transmembrane transportBile salt export pumpHomo sapiens (human)
response to oxidative stressBile salt export pumpHomo sapiens (human)
bile acid metabolic processBile salt export pumpHomo sapiens (human)
response to organic cyclic compoundBile salt export pumpHomo sapiens (human)
bile acid and bile salt transportBile salt export pumpHomo sapiens (human)
canalicular bile acid transportBile salt export pumpHomo sapiens (human)
protein ubiquitinationBile salt export pumpHomo sapiens (human)
regulation of fatty acid beta-oxidationBile salt export pumpHomo sapiens (human)
carbohydrate transmembrane transportBile salt export pumpHomo sapiens (human)
bile acid signaling pathwayBile salt export pumpHomo sapiens (human)
cholesterol homeostasisBile salt export pumpHomo sapiens (human)
response to estrogenBile salt export pumpHomo sapiens (human)
response to ethanolBile salt export pumpHomo sapiens (human)
xenobiotic export from cellBile salt export pumpHomo sapiens (human)
lipid homeostasisBile salt export pumpHomo sapiens (human)
phospholipid homeostasisBile salt export pumpHomo sapiens (human)
positive regulation of bile acid secretionBile salt export pumpHomo sapiens (human)
regulation of bile acid metabolic processBile salt export pumpHomo sapiens (human)
transmembrane transportBile salt export pumpHomo sapiens (human)
G protein-coupled receptor signaling pathwayGlycoprotein hormones alpha chainHomo sapiens (human)
positive regulation of cell population proliferationGlycoprotein hormones alpha chainHomo sapiens (human)
hormone-mediated signaling pathwayGlycoprotein hormones alpha chainHomo sapiens (human)
regulation of signaling receptor activityGlycoprotein hormones alpha chainHomo sapiens (human)
positive regulation of steroid biosynthetic processGlycoprotein hormones alpha chainHomo sapiens (human)
positive regulation of cell migrationGlycoprotein hormones alpha chainHomo sapiens (human)
thyroid gland developmentGlycoprotein hormones alpha chainHomo sapiens (human)
luteinizing hormone secretionGlycoprotein hormones alpha chainHomo sapiens (human)
organ growthGlycoprotein hormones alpha chainHomo sapiens (human)
follicle-stimulating hormone signaling pathwayGlycoprotein hormones alpha chainHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIGlycoprotein hormones alpha chainHomo sapiens (human)
negative regulation of organ growthGlycoprotein hormones alpha chainHomo sapiens (human)
follicle-stimulating hormone secretionGlycoprotein hormones alpha chainHomo sapiens (human)
thyroid hormone generationGlycoprotein hormones alpha chainHomo sapiens (human)
negative regulation of low-density lipoprotein receptor activityIntegrin beta-3Homo sapiens (human)
positive regulation of protein phosphorylationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
cell-substrate junction assemblyIntegrin beta-3Homo sapiens (human)
cell adhesionIntegrin beta-3Homo sapiens (human)
cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
integrin-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
embryo implantationIntegrin beta-3Homo sapiens (human)
blood coagulationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of gene expressionIntegrin beta-3Homo sapiens (human)
negative regulation of macrophage derived foam cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast migrationIntegrin beta-3Homo sapiens (human)
negative regulation of lipid storageIntegrin beta-3Homo sapiens (human)
response to activityIntegrin beta-3Homo sapiens (human)
smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
platelet activationIntegrin beta-3Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
cell-substrate adhesionIntegrin beta-3Homo sapiens (human)
activation of protein kinase activityIntegrin beta-3Homo sapiens (human)
negative regulation of lipid transportIntegrin beta-3Homo sapiens (human)
regulation of protein localizationIntegrin beta-3Homo sapiens (human)
regulation of actin cytoskeleton organizationIntegrin beta-3Homo sapiens (human)
cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of osteoblast proliferationIntegrin beta-3Homo sapiens (human)
heterotypic cell-cell adhesionIntegrin beta-3Homo sapiens (human)
substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
tube developmentIntegrin beta-3Homo sapiens (human)
wound healing, spreading of epidermal cellsIntegrin beta-3Homo sapiens (human)
cellular response to platelet-derived growth factor stimulusIntegrin beta-3Homo sapiens (human)
apolipoprotein A-I-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
wound healingIntegrin beta-3Homo sapiens (human)
apoptotic cell clearanceIntegrin beta-3Homo sapiens (human)
regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
positive regulation of angiogenesisIntegrin beta-3Homo sapiens (human)
positive regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
symbiont entry into host cellIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast proliferationIntegrin beta-3Homo sapiens (human)
mesodermal cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationIntegrin beta-3Homo sapiens (human)
negative regulation of lipoprotein metabolic processIntegrin beta-3Homo sapiens (human)
negative chemotaxisIntegrin beta-3Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosolIntegrin beta-3Homo sapiens (human)
regulation of serotonin uptakeIntegrin beta-3Homo sapiens (human)
angiogenesis involved in wound healingIntegrin beta-3Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascadeIntegrin beta-3Homo sapiens (human)
platelet aggregationIntegrin beta-3Homo sapiens (human)
cellular response to mechanical stimulusIntegrin beta-3Homo sapiens (human)
cellular response to xenobiotic stimulusIntegrin beta-3Homo sapiens (human)
positive regulation of glomerular mesangial cell proliferationIntegrin beta-3Homo sapiens (human)
blood coagulation, fibrin clot formationIntegrin beta-3Homo sapiens (human)
maintenance of postsynaptic specialization structureIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor internalizationIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor diffusion trappingIntegrin beta-3Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
regulation of trophoblast cell migrationIntegrin beta-3Homo sapiens (human)
regulation of extracellular matrix organizationIntegrin beta-3Homo sapiens (human)
cellular response to insulin-like growth factor stimulusIntegrin beta-3Homo sapiens (human)
negative regulation of endothelial cell apoptotic processIntegrin beta-3Homo sapiens (human)
positive regulation of T cell migrationIntegrin beta-3Homo sapiens (human)
cell migrationIntegrin beta-3Homo sapiens (human)
G2/M transition of mitotic cell cycleATP-dependent translocase ABCB1Homo sapiens (human)
xenobiotic metabolic processATP-dependent translocase ABCB1Homo sapiens (human)
response to xenobiotic stimulusATP-dependent translocase ABCB1Homo sapiens (human)
phospholipid translocationATP-dependent translocase ABCB1Homo sapiens (human)
terpenoid transportATP-dependent translocase ABCB1Homo sapiens (human)
regulation of response to osmotic stressATP-dependent translocase ABCB1Homo sapiens (human)
transmembrane transportATP-dependent translocase ABCB1Homo sapiens (human)
transepithelial transportATP-dependent translocase ABCB1Homo sapiens (human)
stem cell proliferationATP-dependent translocase ABCB1Homo sapiens (human)
ceramide translocationATP-dependent translocase ABCB1Homo sapiens (human)
export across plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
transport across blood-brain barrierATP-dependent translocase ABCB1Homo sapiens (human)
positive regulation of anion channel activityATP-dependent translocase ABCB1Homo sapiens (human)
carboxylic acid transmembrane transportATP-dependent translocase ABCB1Homo sapiens (human)
xenobiotic detoxification by transmembrane export across the plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
xenobiotic transport across blood-brain barrierATP-dependent translocase ABCB1Homo sapiens (human)
regulation of chloride transportATP-dependent translocase ABCB1Homo sapiens (human)
positive regulation of leukocyte migrationIntegrin alpha-IIbHomo sapiens (human)
cell-matrix adhesionIntegrin alpha-IIbHomo sapiens (human)
integrin-mediated signaling pathwayIntegrin alpha-IIbHomo sapiens (human)
angiogenesisIntegrin alpha-IIbHomo sapiens (human)
cell-cell adhesionIntegrin alpha-IIbHomo sapiens (human)
cell adhesion mediated by integrinIntegrin alpha-IIbHomo sapiens (human)
G2/M transition of mitotic cell cycleCalmodulin-1Homo sapiens (human)
regulation of heart rateCalmodulin-1Homo sapiens (human)
detection of calcium ionCalmodulin-1Homo sapiens (human)
G protein-coupled receptor signaling pathwayCalmodulin-1Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylationCalmodulin-1Homo sapiens (human)
negative regulation of peptidyl-threonine phosphorylationCalmodulin-1Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumCalmodulin-1Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionCalmodulin-1Homo sapiens (human)
autophagosome membrane dockingCalmodulin-1Homo sapiens (human)
substantia nigra developmentCalmodulin-1Homo sapiens (human)
positive regulation of protein autophosphorylationCalmodulin-1Homo sapiens (human)
regulation of cytokinesisCalmodulin-1Homo sapiens (human)
positive regulation of phosphoprotein phosphatase activityCalmodulin-1Homo sapiens (human)
positive regulation of protein dephosphorylationCalmodulin-1Homo sapiens (human)
cellular response to interferon-betaCalmodulin-1Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STATCalmodulin-1Homo sapiens (human)
regulation of calcium-mediated signalingCalmodulin-1Homo sapiens (human)
positive regulation of cyclic-nucleotide phosphodiesterase activityCalmodulin-1Homo sapiens (human)
response to calcium ionCalmodulin-1Homo sapiens (human)
regulation of cardiac muscle contractionCalmodulin-1Homo sapiens (human)
regulation of ryanodine-sensitive calcium-release channel activityCalmodulin-1Homo sapiens (human)
negative regulation of ryanodine-sensitive calcium-release channel activityCalmodulin-1Homo sapiens (human)
positive regulation of ryanodine-sensitive calcium-release channel activityCalmodulin-1Homo sapiens (human)
cellular response to type II interferonCalmodulin-1Homo sapiens (human)
positive regulation of protein serine/threonine kinase activityCalmodulin-1Homo sapiens (human)
regulation of cardiac muscle cell action potentialCalmodulin-1Homo sapiens (human)
organelle localization by membrane tetheringCalmodulin-1Homo sapiens (human)
negative regulation of high voltage-gated calcium channel activityCalmodulin-1Homo sapiens (human)
regulation of cell communication by electrical coupling involved in cardiac conductionCalmodulin-1Homo sapiens (human)
negative regulation of calcium ion export across plasma membraneCalmodulin-1Homo sapiens (human)
mitochondrion-endoplasmic reticulum membrane tetheringCalmodulin-1Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumCalmodulin Bos taurus (cattle)
negative regulation of ryanodine-sensitive calcium-release channel activityCalmodulin Bos taurus (cattle)
positive regulation of ryanodine-sensitive calcium-release channel activityCalmodulin Bos taurus (cattle)
negative regulation of inflammatory response to antigenic stimulusGuanine nucleotide-binding protein GHomo sapiens (human)
renal water homeostasisGuanine nucleotide-binding protein GHomo sapiens (human)
G protein-coupled receptor signaling pathwayGuanine nucleotide-binding protein GHomo sapiens (human)
regulation of insulin secretionGuanine nucleotide-binding protein GHomo sapiens (human)
cellular response to glucagon stimulusGuanine nucleotide-binding protein GHomo sapiens (human)
peptidyl-serine phosphorylationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
maturation of 5.8S rRNADNA-dependent protein kinase catalytic subunitHomo sapiens (human)
somitogenesisDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
negative regulation of protein phosphorylationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
activation of innate immune responseDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
B cell lineage commitmentDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
immature B cell differentiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
pro-B cell differentiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
T cell lineage commitmentDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
double-strand break repairDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
double-strand break repair via nonhomologous end joiningDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
chromatin remodelingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein phosphorylationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
DNA damage responseDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
brain developmentDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
heart developmentDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
response to gamma radiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
telomere cappingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
peptidyl-serine phosphorylationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
peptidyl-threonine phosphorylationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
mitotic G1 DNA damage checkpoint signalingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein destabilizationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
cellular response to insulin stimulusDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
T cell differentiation in thymusDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
T cell receptor V(D)J recombinationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
small-subunit processome assemblyDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
ectopic germ cell programmed cell deathDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein modification processDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
regulation of circadian rhythmDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of apoptotic processDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
negative regulation of apoptotic processDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
innate immune responseDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of lymphocyte differentiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of erythrocyte differentiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of translationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
rhythmic processDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
regulation of smooth muscle cell proliferationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
regulation of epithelial cell proliferationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
double-strand break repair via alternative nonhomologous end joiningDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
negative regulation of cGAS/STING signaling pathwayDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
regulation of hematopoietic stem cell differentiationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of platelet formationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
positive regulation of double-strand break repair via nonhomologous end joiningDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
immunoglobulin V(D)J recombinationDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
telomere maintenanceDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
regulation of heart rate by cardiac conductionPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of heart rate by hormonePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of membrane potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
positive regulation of DNA-templated transcriptionPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
potassium ion homeostasisPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
cardiac muscle contractionPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of membrane repolarizationPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarizationPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
cellular response to xenobiotic stimulusPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
potassium ion transmembrane transportPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
ventricular cardiac muscle cell action potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
membrane repolarizationPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
membrane depolarization during action potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
membrane repolarization during action potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of heart rate by cardiac conductionPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
potassium ion export across plasma membranePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potentialPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
regulation of potassium ion transmembrane transportPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
negative regulation of potassium ion transmembrane transportPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
positive regulation of potassium ion transmembrane transportPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
negative regulation of potassium ion export across plasma membranePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
potassium ion import across plasma membranePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
cholesterol biosynthetic process3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cholesterol metabolic process3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
hemopoiesis3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cholesterol biosynthetic process via desmosterol3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cholesterol biosynthetic process via lathosterol3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
ossification involved in bone maturation3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
DNA damage responseWD repeat-containing protein 48Homo sapiens (human)
spermatogenesisWD repeat-containing protein 48Homo sapiens (human)
single fertilizationWD repeat-containing protein 48Homo sapiens (human)
multicellular organism growthWD repeat-containing protein 48Homo sapiens (human)
skin developmentWD repeat-containing protein 48Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STATWD repeat-containing protein 48Homo sapiens (human)
embryonic organ developmentWD repeat-containing protein 48Homo sapiens (human)
skeletal system morphogenesisWD repeat-containing protein 48Homo sapiens (human)
homeostasis of number of cellsWD repeat-containing protein 48Homo sapiens (human)
positive regulation of epithelial cell proliferationWD repeat-containing protein 48Homo sapiens (human)
seminiferous tubule developmentWD repeat-containing protein 48Homo sapiens (human)
regulation of protein monoubiquitinationWD repeat-containing protein 48Homo sapiens (human)
positive regulation of double-strand break repair via homologous recombinationWD repeat-containing protein 48Homo sapiens (human)
double-strand break repair via homologous recombinationWD repeat-containing protein 48Homo sapiens (human)
negative regulation of receptor internalizationAtaxin-2Homo sapiens (human)
regulation of translationAtaxin-2Homo sapiens (human)
RNA metabolic processAtaxin-2Homo sapiens (human)
P-body assemblyAtaxin-2Homo sapiens (human)
stress granule assemblyAtaxin-2Homo sapiens (human)
RNA transportAtaxin-2Homo sapiens (human)
lipid transportSigma non-opioid intracellular receptor 1Homo sapiens (human)
nervous system developmentSigma non-opioid intracellular receptor 1Homo sapiens (human)
G protein-coupled opioid receptor signaling pathwaySigma non-opioid intracellular receptor 1Homo sapiens (human)
regulation of neuron apoptotic processSigma non-opioid intracellular receptor 1Homo sapiens (human)
protein homotrimerizationSigma non-opioid intracellular receptor 1Homo sapiens (human)
sterol metabolic processEmopamil-binding protein-likeHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (89)

Processvia Protein(s)Taxonomy
iron ion bindingPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
calcium ion bindingPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
protein bindingPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
lipid bindingPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
linoleate 13S-lipoxygenase activityPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
arachidonate 8(S)-lipoxygenase activityPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
arachidonate 15-lipoxygenase activityPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
linoleate 9S-lipoxygenase activityPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
cysteine-type endopeptidase activityUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
cysteine-type deubiquitinase activityUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
protein bindingUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
peptidase activityUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
protein bindingBile salt export pumpHomo sapiens (human)
ATP bindingBile salt export pumpHomo sapiens (human)
ABC-type xenobiotic transporter activityBile salt export pumpHomo sapiens (human)
bile acid transmembrane transporter activityBile salt export pumpHomo sapiens (human)
canalicular bile acid transmembrane transporter activityBile salt export pumpHomo sapiens (human)
carbohydrate transmembrane transporter activityBile salt export pumpHomo sapiens (human)
ABC-type bile acid transporter activityBile salt export pumpHomo sapiens (human)
ATP hydrolysis activityBile salt export pumpHomo sapiens (human)
hormone activityGlycoprotein hormones alpha chainHomo sapiens (human)
protein bindingGlycoprotein hormones alpha chainHomo sapiens (human)
follicle-stimulating hormone activityGlycoprotein hormones alpha chainHomo sapiens (human)
fibroblast growth factor bindingIntegrin beta-3Homo sapiens (human)
C-X3-C chemokine bindingIntegrin beta-3Homo sapiens (human)
insulin-like growth factor I bindingIntegrin beta-3Homo sapiens (human)
neuregulin bindingIntegrin beta-3Homo sapiens (human)
virus receptor activityIntegrin beta-3Homo sapiens (human)
fibronectin bindingIntegrin beta-3Homo sapiens (human)
protease bindingIntegrin beta-3Homo sapiens (human)
protein disulfide isomerase activityIntegrin beta-3Homo sapiens (human)
protein kinase C bindingIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor bindingIntegrin beta-3Homo sapiens (human)
integrin bindingIntegrin beta-3Homo sapiens (human)
protein bindingIntegrin beta-3Homo sapiens (human)
coreceptor activityIntegrin beta-3Homo sapiens (human)
enzyme bindingIntegrin beta-3Homo sapiens (human)
identical protein bindingIntegrin beta-3Homo sapiens (human)
vascular endothelial growth factor receptor 2 bindingIntegrin beta-3Homo sapiens (human)
metal ion bindingIntegrin beta-3Homo sapiens (human)
cell adhesion molecule bindingIntegrin beta-3Homo sapiens (human)
extracellular matrix bindingIntegrin beta-3Homo sapiens (human)
fibrinogen bindingIntegrin beta-3Homo sapiens (human)
protein bindingATP-dependent translocase ABCB1Homo sapiens (human)
ATP bindingATP-dependent translocase ABCB1Homo sapiens (human)
ABC-type xenobiotic transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
efflux transmembrane transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
ATP hydrolysis activityATP-dependent translocase ABCB1Homo sapiens (human)
transmembrane transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
ubiquitin protein ligase bindingATP-dependent translocase ABCB1Homo sapiens (human)
ATPase-coupled transmembrane transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
xenobiotic transmembrane transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
carboxylic acid transmembrane transporter activityATP-dependent translocase ABCB1Homo sapiens (human)
phosphatidylcholine floppase activityATP-dependent translocase ABCB1Homo sapiens (human)
phosphatidylethanolamine flippase activityATP-dependent translocase ABCB1Homo sapiens (human)
ceramide floppase activityATP-dependent translocase ABCB1Homo sapiens (human)
floppase activityATP-dependent translocase ABCB1Homo sapiens (human)
protein bindingIntegrin alpha-IIbHomo sapiens (human)
identical protein bindingIntegrin alpha-IIbHomo sapiens (human)
metal ion bindingIntegrin alpha-IIbHomo sapiens (human)
extracellular matrix bindingIntegrin alpha-IIbHomo sapiens (human)
molecular adaptor activityIntegrin alpha-IIbHomo sapiens (human)
fibrinogen bindingIntegrin alpha-IIbHomo sapiens (human)
integrin bindingIntegrin alpha-IIbHomo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activityProtein kinase C delta typeRattus norvegicus (Norway rat)
calcium ion bindingCalmodulin-1Homo sapiens (human)
protein bindingCalmodulin-1Homo sapiens (human)
adenylate cyclase activator activityCalmodulin-1Homo sapiens (human)
calcium channel inhibitor activityCalmodulin-1Homo sapiens (human)
protein kinase bindingCalmodulin-1Homo sapiens (human)
titin bindingCalmodulin-1Homo sapiens (human)
protein serine/threonine kinase activator activityCalmodulin-1Homo sapiens (human)
transmembrane transporter bindingCalmodulin-1Homo sapiens (human)
calcium-dependent protein bindingCalmodulin-1Homo sapiens (human)
protein phosphatase activator activityCalmodulin-1Homo sapiens (human)
calcium ion bindingCalmodulin Bos taurus (cattle)
protein bindingCalmodulin Bos taurus (cattle)
protein domain specific bindingCalmodulin Bos taurus (cattle)
G protein activityGuanine nucleotide-binding protein GHomo sapiens (human)
adenylate cyclase activator activityGuanine nucleotide-binding protein GHomo sapiens (human)
double-stranded DNA bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
RNA bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein kinase activityDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein serine/threonine kinase activityDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
DNA-dependent protein kinase activityDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
ATP bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
enzyme bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein domain specific bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
U3 snoRNA bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
histone H2AXS139 kinase activityDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein serine kinase activityDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
transcription cis-regulatory region bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
inward rectifier potassium channel activityPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
voltage-gated potassium channel activityPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
delayed rectifier potassium channel activityPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
protein bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
ubiquitin protein ligase bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
identical protein bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
protein homodimerization activityPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
C3HC4-type RING finger domain bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
scaffold protein bindingPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
C-8 sterol isomerase activity3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
steroid delta-isomerase activity3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
protein binding3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
identical protein binding3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cholestenol delta-isomerase activity3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
DNA bindingWD repeat-containing protein 48Homo sapiens (human)
double-stranded DNA bindingWD repeat-containing protein 48Homo sapiens (human)
single-stranded DNA bindingWD repeat-containing protein 48Homo sapiens (human)
protein bindingWD repeat-containing protein 48Homo sapiens (human)
deubiquitinase activator activityWD repeat-containing protein 48Homo sapiens (human)
ubiquitin bindingWD repeat-containing protein 48Homo sapiens (human)
RNA bindingAtaxin-2Homo sapiens (human)
epidermal growth factor receptor bindingAtaxin-2Homo sapiens (human)
protein bindingAtaxin-2Homo sapiens (human)
mRNA bindingAtaxin-2Homo sapiens (human)
G protein-coupled opioid receptor activitySigma non-opioid intracellular receptor 1Homo sapiens (human)
protein bindingSigma non-opioid intracellular receptor 1Homo sapiens (human)
cholestenol delta-isomerase activityEmopamil-binding protein-likeHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (88)

Processvia Protein(s)Taxonomy
nucleusPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
cytosolPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
cytoskeletonPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
plasma membranePolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
adherens junctionPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
focal adhesionPolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
membranePolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
extracellular exosomePolyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)
nucleusUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
nucleoplasmUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
nucleusUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
cytosolUbiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)
basolateral plasma membraneBile salt export pumpHomo sapiens (human)
Golgi membraneBile salt export pumpHomo sapiens (human)
endosomeBile salt export pumpHomo sapiens (human)
plasma membraneBile salt export pumpHomo sapiens (human)
cell surfaceBile salt export pumpHomo sapiens (human)
apical plasma membraneBile salt export pumpHomo sapiens (human)
intercellular canaliculusBile salt export pumpHomo sapiens (human)
intracellular canaliculusBile salt export pumpHomo sapiens (human)
recycling endosomeBile salt export pumpHomo sapiens (human)
recycling endosome membraneBile salt export pumpHomo sapiens (human)
extracellular exosomeBile salt export pumpHomo sapiens (human)
membraneBile salt export pumpHomo sapiens (human)
extracellular regionGlycoprotein hormones alpha chainHomo sapiens (human)
extracellular spaceGlycoprotein hormones alpha chainHomo sapiens (human)
Golgi lumenGlycoprotein hormones alpha chainHomo sapiens (human)
follicle-stimulating hormone complexGlycoprotein hormones alpha chainHomo sapiens (human)
pituitary gonadotropin complexGlycoprotein hormones alpha chainHomo sapiens (human)
extracellular spaceGlycoprotein hormones alpha chainHomo sapiens (human)
glutamatergic synapseIntegrin beta-3Homo sapiens (human)
nucleusIntegrin beta-3Homo sapiens (human)
nucleoplasmIntegrin beta-3Homo sapiens (human)
plasma membraneIntegrin beta-3Homo sapiens (human)
cell-cell junctionIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
external side of plasma membraneIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
apical plasma membraneIntegrin beta-3Homo sapiens (human)
platelet alpha granule membraneIntegrin beta-3Homo sapiens (human)
lamellipodium membraneIntegrin beta-3Homo sapiens (human)
filopodium membraneIntegrin beta-3Homo sapiens (human)
microvillus membraneIntegrin beta-3Homo sapiens (human)
ruffle membraneIntegrin beta-3Homo sapiens (human)
integrin alphav-beta3 complexIntegrin beta-3Homo sapiens (human)
melanosomeIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
postsynaptic membraneIntegrin beta-3Homo sapiens (human)
extracellular exosomeIntegrin beta-3Homo sapiens (human)
integrin alphaIIb-beta3 complexIntegrin beta-3Homo sapiens (human)
glycinergic synapseIntegrin beta-3Homo sapiens (human)
integrin complexIntegrin beta-3Homo sapiens (human)
protein-containing complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-HMGB1 complexIntegrin beta-3Homo sapiens (human)
receptor complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-vitronectin complexIntegrin beta-3Homo sapiens (human)
alpha9-beta1 integrin-ADAM8 complexIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
cytoplasmATP-dependent translocase ABCB1Homo sapiens (human)
plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
cell surfaceATP-dependent translocase ABCB1Homo sapiens (human)
membraneATP-dependent translocase ABCB1Homo sapiens (human)
apical plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
extracellular exosomeATP-dependent translocase ABCB1Homo sapiens (human)
external side of apical plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
plasma membraneATP-dependent translocase ABCB1Homo sapiens (human)
plasma membraneIntegrin alpha-IIbHomo sapiens (human)
focal adhesionIntegrin alpha-IIbHomo sapiens (human)
cell surfaceIntegrin alpha-IIbHomo sapiens (human)
platelet alpha granule membraneIntegrin alpha-IIbHomo sapiens (human)
extracellular exosomeIntegrin alpha-IIbHomo sapiens (human)
integrin alphaIIb-beta3 complexIntegrin alpha-IIbHomo sapiens (human)
blood microparticleIntegrin alpha-IIbHomo sapiens (human)
integrin complexIntegrin alpha-IIbHomo sapiens (human)
external side of plasma membraneIntegrin alpha-IIbHomo sapiens (human)
cytosolProtein kinase C delta typeRattus norvegicus (Norway rat)
cytosolProtein kinase C zeta typeRattus norvegicus (Norway rat)
spindle poleCalmodulin-1Homo sapiens (human)
extracellular regionCalmodulin-1Homo sapiens (human)
nucleusCalmodulin-1Homo sapiens (human)
nucleoplasmCalmodulin-1Homo sapiens (human)
cytoplasmCalmodulin-1Homo sapiens (human)
centrosomeCalmodulin-1Homo sapiens (human)
cytosolCalmodulin-1Homo sapiens (human)
spindle microtubuleCalmodulin-1Homo sapiens (human)
plasma membraneCalmodulin-1Homo sapiens (human)
sarcomereCalmodulin-1Homo sapiens (human)
vesicleCalmodulin-1Homo sapiens (human)
myelin sheathCalmodulin-1Homo sapiens (human)
sperm midpieceCalmodulin-1Homo sapiens (human)
voltage-gated potassium channel complexCalmodulin-1Homo sapiens (human)
protein-containing complexCalmodulin-1Homo sapiens (human)
calcium channel complexCalmodulin-1Homo sapiens (human)
catalytic complexCalmodulin-1Homo sapiens (human)
cytoplasmCalmodulin-1Homo sapiens (human)
plasma membraneGamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)
cytosolCalmodulin Bos taurus (cattle)
spindle poleCalmodulin Bos taurus (cattle)
cytoplasmCalmodulin Bos taurus (cattle)
protein-containing complexCalmodulin Bos taurus (cattle)
plasma membraneGamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)
plasma membraneGuanine nucleotide-binding protein GHomo sapiens (human)
plasma membraneGamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)
chromosome, telomeric regionDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
nucleusDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
nucleoplasmDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
nucleolusDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
cytosolDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
membraneDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
DNA-dependent protein kinase complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
chromatinDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
transcription regulator complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
DNA-dependent protein kinase-DNA ligase 4 complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
small-subunit processomeDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein-containing complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
protein-DNA complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
nonhomologous end joining complexDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
nucleusDNA-dependent protein kinase catalytic subunitHomo sapiens (human)
plasma membranePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
cell surfacePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
perinuclear region of cytoplasmPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
voltage-gated potassium channel complexPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
inward rectifier potassium channel complexPotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
plasma membranePotassium voltage-gated channel subfamily H member 2Homo sapiens (human)
nuclear envelope3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
endoplasmic reticulum3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
endoplasmic reticulum membrane3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cytoplasmic vesicle3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
nuclear membrane3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
endoplasmic reticulum3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)
cytoplasmWD repeat-containing protein 48Homo sapiens (human)
nucleusWD repeat-containing protein 48Homo sapiens (human)
nucleoplasmWD repeat-containing protein 48Homo sapiens (human)
lysosomeWD repeat-containing protein 48Homo sapiens (human)
late endosomeWD repeat-containing protein 48Homo sapiens (human)
cytosolWD repeat-containing protein 48Homo sapiens (human)
intracellular membrane-bounded organelleWD repeat-containing protein 48Homo sapiens (human)
cytoplasmAtaxin-2Homo sapiens (human)
Golgi apparatusAtaxin-2Homo sapiens (human)
trans-Golgi networkAtaxin-2Homo sapiens (human)
cytosolAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
membraneAtaxin-2Homo sapiens (human)
perinuclear region of cytoplasmAtaxin-2Homo sapiens (human)
ribonucleoprotein complexAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
nuclear envelopeSigma non-opioid intracellular receptor 1Homo sapiens (human)
nuclear inner membraneSigma non-opioid intracellular receptor 1Homo sapiens (human)
nuclear outer membraneSigma non-opioid intracellular receptor 1Homo sapiens (human)
endoplasmic reticulumSigma non-opioid intracellular receptor 1Homo sapiens (human)
endoplasmic reticulum membraneSigma non-opioid intracellular receptor 1Homo sapiens (human)
lipid dropletSigma non-opioid intracellular receptor 1Homo sapiens (human)
cytosolSigma non-opioid intracellular receptor 1Homo sapiens (human)
postsynaptic densitySigma non-opioid intracellular receptor 1Homo sapiens (human)
membraneSigma non-opioid intracellular receptor 1Homo sapiens (human)
growth coneSigma non-opioid intracellular receptor 1Homo sapiens (human)
cytoplasmic vesicleSigma non-opioid intracellular receptor 1Homo sapiens (human)
anchoring junctionSigma non-opioid intracellular receptor 1Homo sapiens (human)
postsynaptic density membraneSigma non-opioid intracellular receptor 1Homo sapiens (human)
endoplasmic reticulumSigma non-opioid intracellular receptor 1Homo sapiens (human)
endoplasmic reticulumEmopamil-binding protein-likeHomo sapiens (human)
endoplasmic reticulum membraneEmopamil-binding protein-likeHomo sapiens (human)
endoplasmic reticulumEmopamil-binding protein-likeHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (360)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID504749qHTS profiling for inhibitors of Plasmodium falciparum proliferation2011Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID588378qHTS for Inhibitors of ATXN expression: Validation
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
AID1347104qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347112qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347124qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347107qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347116qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347126qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347102qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347096qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347090qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347109qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347122qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347114qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347121qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347111qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347093qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347106qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347110qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for A673 cells)2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347128qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347129qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347100qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347118qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347119qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347113qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347115qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347117qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347091qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347127qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347123qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347125qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID554931Inhibition of Candida krusei ABC1 expressed in Saccharomyces cerevisiae isolate ADdelta at 620 nM2009Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
AID1221982Fraction absorbed in human2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID1079935Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source]
AID1545810Inhibition of mammosphere formation in human SUM159 cells assessed as reduction in number of mammosphere at 2 uM incubated for 10 days by microscopic analysis2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID1443987Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell membrane vesicles assessed as reduction in ATP-dependent [3H]-taurocholate uptake in to vesicles after 5 mins by TopCount method2014Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
AID264908Inhibition of PMA-induced superoxide formation in Sprague-Dawley rat neutrophil at 10 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID588210Human drug-induced liver injury (DILI) modelling dataset from Ekins et al2010Drug metabolism and disposition: the biological fate of chemicals, Dec, Volume: 38, Issue:12
A predictive ligand-based Bayesian model for human drug-induced liver injury.
AID1245896Inhibition of ERK phosphorylation in human NCI-H1650 cells at 20 to 40 uM after 12 hrs by Western blot analysis2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1221956Apparent permeability from apical to basolateral side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID532573Antimicrobial activity against Salmonella serovar Typhimurium SL1344 by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID61331Compound was tested for its effect on dopamine saturation analysis1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID562243Antimycobacterial activity against Mycobacterium smegmatis grown in Luria-Bertani broth medium assessed as growth inhibition in mid-logarithmic phase by GFP-based fluorescence assay2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID588219FDA HLAED, gamma-glutamyl transferase (GGT) increase2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID61323Compound was tested for its effect on dopamine saturation analysis1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID29139Calculated dissociation constant (pKa, calculated with ACD/pKa)2002Journal of medicinal chemistry, Dec-19, Volume: 45, Issue:26
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
AID324543Increase in light chain 3-GFP+ autophagosome vesicle intensity per cell in human H4 cells at 8.3 uM after 24 hrs by high throughput fluorescence microscopy relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID336802Antiinflammatory activity in fMLP/cytochalasin B stimulated rat neutrophils assessed as inhibition of beta-glucuronidase release preincubated for 10 mins measured 45 mins after fMLP/cytochalasin B challenge2003Journal of natural products, Mar, Volume: 66, Issue:3
Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida.
AID588214FDA HLAED, liver enzyme composite activity2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID1079948Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source]
AID310931Partition coefficient, log P of the compound2007Journal of medicinal chemistry, Feb-22, Volume: 50, Issue:4
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
AID1623307Antiproliferative activity against human U3005MG cells by CellTiter-Glo assay2019European journal of medicinal chemistry, Feb-15, Volume: 164Recent advances in the discovery of small molecules targeting glioblastoma.
AID1245902Binding affinity to dopamine D5 receptor (unknown origin) at 0.1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID40449Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CB2004Bioorganic & medicinal chemistry letters, Feb-23, Volume: 14, Issue:4
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
AID264896Inhibition of fMLP-induced superoxide formation in Sprague-Dawley rat neutrophil at 3 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID311935Partition coefficient, log P of the compound2008Journal of medicinal chemistry, Jan-24, Volume: 51, Issue:2
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
AID1245904Binding affinity to dopamine D2 receptor (unknown origin) at 1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1148006Binding affinity to bovine serum albumin by circular dichroic probe technique1977Journal of medicinal chemistry, Mar, Volume: 20, Issue:3
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
AID625288Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID562242Antimycobacterial activity against Mycobacterium smegmatis grown in nitrogen -limited broth medium assessed as growth inhibition in mid-logarithmic phase by spectrophotometry2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID324604Effect on mTOR phosphorylation in human H4 cells at 8.3 uM after 4 hrs2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID562240Antimycobacterial activity against Mycobacterium smegmatis grown in Luria-Bertani broth medium assessed as growth inhibition in mid-logarithmic phase by spectrophotometry2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID1161119Inhibition of NDH2 in Mycobacterium smegmatis (MC2) 155 membranes assessed NADH oxidation relative to control2014Bioorganic & medicinal chemistry, Oct-01, Volume: 22, Issue:19
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.
AID264910Inhibition of PMA-induced superoxide formation in Sprague-Dawley rat neutrophil at 1 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID205267Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex1985Journal of medicinal chemistry, Mar, Volume: 28, Issue:3
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
AID264904Formation of PMA-induced superoxide in Sprague-Dawley rat neutrophil at 10 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1079945Animal toxicity known. [column 'TOXIC' in source]
AID324387Induction of light chain 3-GFP level in human H4 cells at 8.3 uM after 24 hrs by high throughput fluorescence microscopy relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID588216FDA HLAED, serum glutamic oxaloacetic transaminase (SGOT) increase2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID65908Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatum1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID324589Increase in ratio of light chain 3 subunit 2 to light chain 3 subunit 1 in human H4 cells at 8.3 uM after 4 hrs by Western blot2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID4362Binding affinity towards 5-hydroxytryptamine 1A receptor by displacing [3H]WB-4101 from rat hippocampus1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID496830Antimicrobial activity against Leishmania major2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID625279Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID1221963Transporter substrate index ratio of permeability from apical to basolateral side in human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID1245892Cell cycle arrest in human NCI-H1650 cells assessed as accumulation at sub-G1 phase at 1 to 40 uM by propidium iodide staining-based flow cytometric analysis2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID25603Dissociation constant was reported1981Journal of medicinal chemistry, Nov, Volume: 24, Issue:11
Side-chain effects on phenothiazine cation radical reactions.
AID1245895Inhibition of AKT phosphorylation in human NCI-H1650 cells at 20 to 40 uM after 12 hrs by Western blot analysis2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1395910Induction of intracellular Ca2+ level in human U87MG cells by Fura-2 AM dye-based assay2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID1623306Antiproliferative activity against human U3046MG cells by CellTiter-Glo assay2019European journal of medicinal chemistry, Feb-15, Volume: 164Recent advances in the discovery of small molecules targeting glioblastoma.
AID588209Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset2010Chemical research in toxicology, Jul-19, Volume: 23, Issue:7
Developing structure-activity relationships for the prediction of hepatotoxicity.
AID1221965Transporter substrate index of efflux ratio in human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID264907Formation of PMA-induced superoxide in Sprague-Dawley rat neutrophil at 3 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID625291Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID496832Antimicrobial activity against Trypanosoma brucei rhodesiense2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID681127TP_TRANSPORTER: inhibition of LDS-751 efflux in NIH-3T3-G185 cells2001Biochemical and biophysical research communications, Nov-30, Volume: 289, Issue:2
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
AID625277FDA Liver Toxicity Knowledge Base Benchmark Dataset (LTKB-BD) drugs of less concern for DILI2011Drug discovery today, Aug, Volume: 16, Issue:15-16
FDA-approved drug labeling for the study of drug-induced liver injury.
AID1474167Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status2016Drug discovery today, Apr, Volume: 21, Issue:4
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
AID264899Inhibition of fMLP-induced superoxide formation in Sprague-Dawley rat neutrophil2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1443992Total Cmax in human administered as single dose2014Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
AID1354682Antiplasmodial activity against Plasmodium falciparum FCB infected in human erythrocytes after 30 mins by FACS analysis2018Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18
Plasmodial Kinase Inhibitors: License to Cure?
AID178541Compound was tested for its ability to induce catalepsy in rats.1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID214654Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductase (linear competitive type)1998Journal of medicinal chemistry, Jan-15, Volume: 41, Issue:2
Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
AID1079944Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source]
AID264897Inhibition of fMLP-induced superoxide formation in Sprague-Dawley rat neutrophil at 10 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID324595Reduction of poly(Q) level in human H4 cells expressing EGFP-Q79-HA after 24 hrs2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID1245905Binding affinity to dopamine D3 receptor (unknown origin) at 1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID178197Effective dose in blocking conditioned avoidance responding (CAR) in the rat when administered intraperitoneally1989Journal of medicinal chemistry, May, Volume: 32, Issue:5
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
AID1297599Association constant, pKa of the compound2016European journal of medicinal chemistry, Jun-30, Volume: 116The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
AID1497823Inhibition of wild type Caldalkalibacillus thermarum TA2.A1 NDH2 preincubated for 1 hr followed by NADH addition measured after 8 mins2018Bioorganic & medicinal chemistry letters, 07-15, Volume: 28, Issue:13
'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase.
AID1221962Efflux ratio of permeability from apical to basolateral side over basolateral to apical side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID625287Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID607091Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID1079943Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source]
AID1215122Percentage unbound in solid supported porcine brain membrane vesicles at 5 uM by TRANSIL assay2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID1545794Antiproliferative activity against human SKBR3 cells assessed as reduction in cell viability incubated for 2 days by MTT assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID1519961Inhibition of Nedd8-cullin1 adduct formation in human A549 cells assessed as decrease in cullin1 neddylation at 100 uM incubated for 6 to 12 hrs by Western blot analysis2020European journal of medicinal chemistry, Jan-01, Volume: 185Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.
AID588217FDA HLAED, serum glutamic pyruvic transaminase (SGPT) increase2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID1079942Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source]
AID1245899Binding affinity to dopamine D2 receptor (unknown origin) at 0.1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1297607Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+2016European journal of medicinal chemistry, Jun-30, Volume: 116The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
AID1449628Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-taurocholate transport into vesicles incubated for 5 mins by Topcount based rapid filtration method2012Drug metabolism and disposition: the biological fate of chemicals, Dec, Volume: 40, Issue:12
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
AID1297600Competitive binding affinity to human CaM mutant in presence of 2,6-anilino naphthalene sulfonate by fluorescence analysis2016European journal of medicinal chemistry, Jun-30, Volume: 116The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
AID1395919Cytotoxicity against human NSC cells assessed as reduction in cell viability at 1 to 20 uM after 24 hrs by MTT assay relative to control2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID532574Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing acrB::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID75299Inhibitory activity against human erythrocyte glutathione reductase; '*' indicates No inhibition1998Journal of medicinal chemistry, Jan-15, Volume: 41, Issue:2
Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
AID1545813Inhibition of cell migration of human MDA-MB-231 cells at 5.40 uM incubated for 48 hrs by scratch wound healing assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID1148003Dissociation constant, pKa of the compound by UV-visible spectrophotometer analysis1977Journal of medicinal chemistry, Mar, Volume: 20, Issue:3
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
AID179777In vitro inhibitory effect on neutrophil superoxide formation isolated from pentobarbital-anesthetized rats2001Bioorganic & medicinal chemistry letters, Aug-06, Volume: 11, Issue:15
Benzyloxybenzaldehyde analogues as novel adenylyl cyclase activators.
AID241445Inhibitory concentration against hepatitis C virus helicase; range 0.6-0.72005Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
Control of hepatitis C: a medicinal chemistry perspective.
AID1148004Oleyl alcohol-water partition coefficient, Rm of the compound measured at 0% methanol by reverse-phase thin layer chromatography1977Journal of medicinal chemistry, Mar, Volume: 20, Issue:3
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
AID324583Increase in long-lived protein degradation in human H4 cells after 2 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID723649Binding affinity to emopamil binding protein (unknown origin)2013Bioorganic & medicinal chemistry, Jan-01, Volume: 21, Issue:1
Synthesis and biological evaluation of ¹⁸F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging.
AID1395915Cytotoxicity against human GBL28 cells assessed as reduction in cell viability after 24 hrs by MTT assay2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID1395917Cytotoxicity against human U87MG cells assessed as reduction in cell viability at 1 to 20 uM after 24 hrs by MTT assay relative to control2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID532579Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing soxS::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID1221964Transporter substrate index ratio of permeability from basolateral to apical side in human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID496818Antimicrobial activity against Trypanosoma brucei brucei2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID19262Aqueous solubility2000Bioorganic & medicinal chemistry letters, Jun-05, Volume: 10, Issue:11
Prediction of drug solubility from Monte Carlo simulations.
AID723648Selectivity index, ratio of Ki for sigma 1 receptor (unknown origin) to Ki for emopamil binding protein (unknown origin)2013Bioorganic & medicinal chemistry, Jan-01, Volume: 21, Issue:1
Synthesis and biological evaluation of ¹⁸F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging.
AID496826Antimicrobial activity against Entamoeba histolytica2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID189473Apparent partition coefficient was measured as histamine releasing activity in rat mast cells.1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID605817Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 7.5 uM calcium ions2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID581672Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay2009Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
AID1605042Inhibition of porcine cerebellar microsomes SERCA2b incubated for 10 mins by enzyme-coupled method2020Journal of medicinal chemistry, 03-12, Volume: 63, Issue:5
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
AID178868Compound was tested for the inhibition of apomorphine-induced stereotype1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID311934Dissociation constant, pKa of the compound2008Journal of medicinal chemistry, Jan-24, Volume: 51, Issue:2
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
AID264911Inhibition of PMA-induced superoxide formation in Sprague-Dawley rat neutrophil at 3 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1395912Induction of intracellular Ca2+ level in human NSC cells at 100 uM by Fura-2 AM dye-based assay2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID532578Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing marA::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID36847In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-41011986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID588218FDA HLAED, lactate dehydrogenase (LDH) increase2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID5047Compound was tested for its effect on 5-hydroxytryptamine 2 receptor saturation analysis1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID1221960Apparent permeability from apical to basolateral side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID1221957Apparent permeability from basolateral to apical side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID264893Formation of fMLP-induced superoxide in Sprague-Dawley rat neutrophil at 3 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1079940Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source]
AID239296Affinity for ERG2 of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligand2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
AID404335Binding affinity to calmodulin2008Journal of medicinal chemistry, Jun-12, Volume: 51, Issue:11
Interaction of antagonists with calmodulin: insights from molecular dynamics simulations.
AID496825Antimicrobial activity against Leishmania mexicana2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID681126TP_TRANSPORTER: inhibition of Rhodamine 123 efflux in NIH-3T3-G185 cells2001Biochemical and biophysical research communications, Nov-30, Volume: 289, Issue:2
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
AID324572Increase in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 2 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID625282Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID324582Increase in long-lived protein degradation in human H4 cells after 1 hr relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID581806Inhibition of Saccharomyces cerevisiae MKPDR5h multidrug transporter Pdr5p assessed as concentration required to threefold increase in rate of fluorescence signal relative to absence of inhibitor by fluorescein diacetate based high-throughput screening sp2009Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
AID1079934Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source]
AID605818Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 10 uM calcium ions2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID454662Antiinflammatory activity against Sprague-Dawley rat neutrophils assessed as inhibition of fMLP/cytochalasin B-induced beta-glucuronidase release2009Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
Furo[3',2':3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis.
AID705447Inhibition of DNA-PK in human U1810 cells after 30 mins2012Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
Modulation of DNA repair by pharmacological inhibitors of the PIKK protein kinase family.
AID165122Inhibition of protein kinase C1999Bioorganic & medicinal chemistry letters, Aug-02, Volume: 9, Issue:15
Novel protein kinase C inhibitors: synthesis and PKC inhibition of beta-substituted polythiophene derivatives.
AID103232Anti MDR activity was expressed as MDR ratio or MDR fold reversal in doxorubicin resistant human breast carcinoma tumor cell line MCF-7/DOX1998Journal of medicinal chemistry, May-21, Volume: 41, Issue:11
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
AID194153The percent loss of escape responding was determined for the estimated effective dose 50 values for CAR block1989Journal of medicinal chemistry, May, Volume: 32, Issue:5
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
AID295641Displacement of [3H]YM091512 from dopamine D2 receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID588215FDA HLAED, alkaline phosphatase increase2004Current drug discovery technologies, Dec, Volume: 1, Issue:4
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
AID1079946Presence of at least one case with successful reintroduction. [column 'REINT' in source]
AID180162Antipsychotic activity at a dose 10 times the ED50 value for CAR block for production of catalepsy in the rat (following i.p. dosing)1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID324584Increase in long-lived protein degradation in human H4 cells after 4 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID1079947Comments (NB not yet translated). [column 'COMMENTAIRES' in source]
AID625289Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID1221961Apparent permeability from basolateral to apical side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis in presence of 1 uM of P-gp inhibitor LY3359792011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID264912Inhibition of PMA-induced superoxide formation in Sprague-Dawley rat neutrophil2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID496831Antimicrobial activity against Cryptosporidium parvum2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID562244Antimycobacterial activity against Mycobacterium smegmatis grown in carbon-limited broth medium assessed as growth inhibition in mid-logarithmic phase by GFP-based fluorescence assay2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID497005Antimicrobial activity against Pneumocystis carinii2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID1079936Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source]
AID625290Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID1215121Fraction unbound in Wistar rat brain homogenate at 5 uM after 5 hrs by equilibrium dialysis method2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID295640Displacement of [3H]SCH-23390 from dopamine D1 receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID496817Antimicrobial activity against Trypanosoma cruzi2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID624608Specific activity of expressed human recombinant UGT1A42000Annual review of pharmacology and toxicology, , Volume: 40Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
AID625280Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID1395918Cytotoxicity against human GBL28 cells assessed as reduction in cell viability at 1 to 20 uM after 24 hrs by MTT assay relative to control2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID4848Compound was tested for its effect on 5-hydroxytryptamine 2 receptor saturation analysis1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID180321Inhibitory effect of compound on superoxide anion generation in rat neutrophils stimulated with PMA2004Bioorganic & medicinal chemistry letters, Feb-23, Volume: 14, Issue:4
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
AID532576Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing acrF::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID295643Displacement of [3H]8-OH-DPAT from 5HT1A receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID496827Antimicrobial activity against Leishmania amazonensis2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID496824Antimicrobial activity against Toxoplasma gondii2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID26396Partition coefficient (logD7.4)1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID699027Binding affinity to HIV 1 fluorescein-labeled SL3 RNA by fluorescence spectrometry2012Journal of medicinal chemistry, May-10, Volume: 55, Issue:9
Identification of small molecule inhibitors of the HIV-1 nucleocapsid-stem-loop 3 RNA complex.
AID35435The compound was tested for its binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]WB-4101 radioligand in rat cerebral cortex1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID1245906Binding affinity to dopamine D4 receptor (unknown origin) at 1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID562241Antimycobacterial activity against Mycobacterium smegmatis grown in carbon-limited broth medium assessed as growth inhibition in mid-logarithmic phase by spectrophotometry2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID581807Inhibition of Saccharomyces cerevisiae MKCDR1h multidrug transporter Cdr1p assessed as concentration required to threefold increase in rate of fluorescence signal relative to absence of inhibitor by fluorescein diacetate based high-throughput screening sp2009Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
AID562245Antimycobacterial activity against Mycobacterium smegmatis grown in nitrogen -limited broth medium assessed as growth inhibition in mid-logarithmic phase by GFP-based fluorescence assay2009Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
AID1245907Binding affinity to dopamine D5 receptor (unknown origin) at 1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1545799Antiproliferative activity against human KG1a cells assessed as reduction in cell viability incubated for 2 days by MTT assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID1474166Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index2016Drug discovery today, Apr, Volume: 21, Issue:4
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
AID1079938Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source]
AID150616Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model2002Journal of medicinal chemistry, Dec-19, Volume: 45, Issue:26
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
AID625284Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID496821Antimicrobial activity against Leishmania2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID1354681Inhibition of Plasmodium falciparum His-tagged CDPK4 expressed in Escherichia coli BL21(DE3) using EGTA as substrate after 10 mins in presence of ATP2018Journal of medicinal chemistry, 09-27, Volume: 61, Issue:18
Plasmodial Kinase Inhibitors: License to Cure?
AID1545791Antiproliferative activity against human SUM159 cells assessed as reduction in cell viability incubated for 2 days by MTT assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID532577Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing tolC::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID108138Inhibitory activity against mast cell degranulation by measuring the content of beta-glucuronidase in the supernatant2002Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives.
AID1079949Proposed mechanism(s) of liver damage. [column 'MEC' in source]
AID1395926Induction of intracellular Ca2+ level in human U87MG cells at 1 to 100 uM by Fura-2 AM dye-based assay relative to control2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID605819Inhibition of human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID1545793Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 2 days by MTT assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID61326Compound was tested in vitro for its affinity towards rat striatal Dopamine receptor D2 labeled with [3H]- spiperone1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID496829Antimicrobial activity against Leishmania infantum2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID327647Inhibition of wild type androgen receptor expressed in CV1 cells assessed as dihydrotestosterone-stimulated transactivation at 500 nM by CAT reporter gene assay2007Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs.
AID581808Inhibition of Saccharomyces cerevisiae MKSNQ2h multidrug transporter Snq2p assessed as concentration required to threefold increase in rate of fluorescence signal relative to absence of inhibitor by fluorescein diacetate based high-throughput screening sp2009Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
AID102993Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB2004Bioorganic & medicinal chemistry letters, Feb-23, Volume: 14, Issue:4
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
AID180322Inhibitory effect of compound on superoxide anion generation in rat neutrophils stimulated with fMLP/CB2004Bioorganic & medicinal chemistry letters, Feb-23, Volume: 14, Issue:4
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
AID3700The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortex1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID264902Formation of fMLP-induced superoxide in Sprague-Dawley rat neutrophil at 5 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID295639Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID625292Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID336035Inhibition of rat brain PKC1993Journal of natural products, Oct, Volume: 56, Issue:10
Kinase inhibitors from Polygonum cuspidatum.
AID42111BSA binding (log K)1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID603955In-vivo blood to lung partition coefficients of the compound, logP(lung) in rat2008European journal of medicinal chemistry, Mar, Volume: 43, Issue:3
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
AID625281Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID324573Increase in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 4 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID699031Binding affinity to single stranded RNA by fluorescence spectrometry2012Journal of medicinal chemistry, May-10, Volume: 55, Issue:9
Identification of small molecule inhibitors of the HIV-1 nucleocapsid-stem-loop 3 RNA complex.
AID1215124Binding affinity to Wistar rat brain lipid assessed as percentage unbound by TRANSIL assay2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID26519Partition coefficient (logD) (HPLC)1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID1245903Binding affinity to dopamine D1 receptor (unknown origin) at 1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID205268Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex at 10 uM1985Journal of medicinal chemistry, Mar, Volume: 28, Issue:3
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
AID496820Antimicrobial activity against Trypanosoma brucei2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID681131TP_TRANSPORTER: inhibition of Daunorubicin efflux in NIH-3T3-G185 cells2001Biochemical and biophysical research communications, Nov-30, Volume: 289, Issue:2
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
AID1079937Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source]
AID1221958Efflux ratio of permeability from apical to basolateral side over basolateral to apical side of human Caco2 cells at 10 uM up to 120 mins by HPLC-MC analysis2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
AID1315765Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assay2016Journal of medicinal chemistry, Oct-27, Volume: 59, Issue:20
Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.
AID5307The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cortex1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID295645Displacement of [3H]mesulergine from 5HT2C receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID324585Increase in long-lived protein degradation in human H4 cells after 24 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID146870The compound was tested for its ability to inhibit Na+/K+ ATPase in rat brain.1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID624607Specific activity of expressed human recombinant UGT1A32000Annual review of pharmacology and toxicology, , Volume: 40Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
AID1245900Binding affinity to dopamine D3 receptor (unknown origin) at 0.1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID454661Antiinflammatory activity against Sprague-Dawley rat neutrophils assessed as inhibition of fMLP/cytochalasin B-induced lysozyme release2009Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
Furo[3',2':3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis.
AID186206Log (1/ED50*10e-3) was measured as histamine releasing activity in rat mast cells. c1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID23971logD (measured by HPLC) (as log k')1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID625286Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID294052Antiproliferative activity against human Caco-2 cells assessed as cell viability by MTT assay after 48 hrs2007Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance.
AID1161115Inhibition of Mycobacterium tuberculosis NDH22014Bioorganic & medicinal chemistry, Oct-01, Volume: 22, Issue:19
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.
AID1497821Inhibition of C-terminal His-tagged Caldalkalibacillus thermarum TA2.A1 NDH2 R382C mutant preincubated for 1 hr followed by NADH addition measured after 8 mins2018Bioorganic & medicinal chemistry letters, 07-15, Volume: 28, Issue:13
'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase.
AID1161117Antimicrobial activity against Mycobacterium tuberculosis H37Ra after 5 days by serial macrobroth dilution method2014Bioorganic & medicinal chemistry, Oct-01, Volume: 22, Issue:19
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.
AID1215120Binding affinity to Wistar rat brain lipid by TRANSIL assay2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID532580Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID1395914Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by MTT assay2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID1605053Inhibition of rabbit skeletal muscle microsomes SERCA1a incubated for 10 mins by enzyme-coupled method2020Journal of medicinal chemistry, 03-12, Volume: 63, Issue:5
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
AID1297606Binding affinity to bovine brain CaM by FTPFACE analysis2016European journal of medicinal chemistry, Jun-30, Volume: 116The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
AID23961logD (measured by HPLC) (as log k')1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID264894Formation of fMLP-induced superoxide in Sprague-Dawley rat neutrophil at 10 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1297601Binding affinity to porcine brain CaM by HPLC analysis2016European journal of medicinal chemistry, Jun-30, Volume: 116The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
AID1443995Hepatotoxicity in human assessed as drug-induced liver injury2014Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
AID214488Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductase1998Journal of medicinal chemistry, Jan-15, Volume: 41, Issue:2
Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
AID1395916Cytotoxicity against human NSC cells assessed as reduction in cell viability after 24 hrs by MTT assay2018European journal of medicinal chemistry, May-10, Volume: 151Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
AID1079933Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is
AID239597Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
AID29141Apparent value (pKa) calculated with ACD/pKa (single pKa value)2002Journal of medicinal chemistry, Dec-19, Volume: 45, Issue:26
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
AID1283269Inhibition of DR24 in Dhcr7-deficient mouse Neuro2a cells assessed as decrease in 7-DHC levels at 1 uM by LC-MS/GC-MS analysis2016Journal of medicinal chemistry, Feb-11, Volume: 59, Issue:3
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
AID29140Apparent value (pKa) calculated with ACD/pKa (experimental pKa value)2002Journal of medicinal chemistry, Dec-19, Volume: 45, Issue:26
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
AID165140Inhibition of protein kinase C(1:1mixture of PKC alpha & beta) expressed in Sf9 insect cells1998Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
Novel protein kinase C inhibitors: alpha-terthiophene derivatives.
AID1215127Ratio of fraction unbound in solid supported porcine brain membrane vesicles at 5 uM by TRANSIL assay to fraction unbound in Wistar rat brain homogenate at 5 uM after 5 hrs by equilibrium dialysis method2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID699030Binding affinity to double stranded RNA by fluorescence spectrometry2012Journal of medicinal chemistry, May-10, Volume: 55, Issue:9
Identification of small molecule inhibitors of the HIV-1 nucleocapsid-stem-loop 3 RNA complex.
AID1079941Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source]
AID496828Antimicrobial activity against Leishmania donovani2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID1545792Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 2 days by MTT assay2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID1161120Inhibition of NDH2 in Mycobacterium smegmatis (MC2) 155 membrane assessed inhibition of oxygen consumption relative to control2014Bioorganic & medicinal chemistry, Oct-01, Volume: 22, Issue:19
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.
AID108139Inhibitory activity against mast cell degranulation by measuring the content of histamine in the supernatant2002Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives.
AID607092Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 2.5 uM calcium ions2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID1545804Inhibition of colony formation in human MCF7 cells at 2.83 uM incubated for 14 days with replacement of medium for every 3 or 4 days by crystal violet staining based visual analysis relative to control2019European journal of medicinal chemistry, Dec-01, Volume: 183Design, synthesis and evaluation of novel phenothiazine derivatives as inhibitors of breast cancer stem cells.
AID264903Inhibition of fMLP-induced superoxide formation in Sprague-Dawley rat neutrophil at 5 uM2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID1519960Inhibition of Nedd8-cullin1 (unknown origin) adduct formation assessed as decrease in cullin1 neddylation at 50 uM preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis2020European journal of medicinal chemistry, Jan-01, Volume: 185Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.
AID26521Partition coefficient (logD) (HPLC)1981Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
AID1215123Binding affinity to Wistar rat serum albumin2011Drug metabolism and disposition: the biological fate of chemicals, Feb, Volume: 39, Issue:2
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
AID496823Antimicrobial activity against Trichomonas vaginalis2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID1161116Antimicrobial activity against Mycobacterium smegmatis (MC2) 155 after 24 hrs by serial macrobroth dilution method2014Bioorganic & medicinal chemistry, Oct-01, Volume: 22, Issue:19
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.
AID1245898Binding affinity to dopamine D1 receptor (unknown origin) at 0.1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID605816Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 5 uM calcium ions2011Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11
Development of the fluorescent biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a novel tool for discovering new calmodulin inhibitors and detecting calcium.
AID532575Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing acrD::aph mutant by broth dilution method2008Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
AID294583Inhibition of 1 uM fMLP-stimulated beta-Glucuronidase release from rat neutrophils2007European journal of medicinal chemistry, May, Volume: 42, Issue:5
Synthetic 2',5'-dimethoxychalcones as G(2)/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages.
AID294584Inhibition of 5 ug/ml CB-stimulated Lysozyme release from rat neutrophils2007European journal of medicinal chemistry, May, Volume: 42, Issue:5
Synthetic 2',5'-dimethoxychalcones as G(2)/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages.
AID1245889Cytotoxicity against human NCI-H1650 cells assessed as growth inhibition after 48 hrs by MTT assay2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID1079939Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source]
AID295642Displacement of [3H]YM091512 from dopamine D3 receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID324439Increase in light chain 3-GFP+ autophagosome vesicle number per cell in human H4 cells at 8.3 uM after 24 hrs by high throughput fluorescence microscopy relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID1497822Inhibition of C-terminal His-tagged Caldalkalibacillus thermarum TA2.A1 NDH2 R347C mutant preincubated for 1 hr followed by NADH addition measured after 8 mins2018Bioorganic & medicinal chemistry letters, 07-15, Volume: 28, Issue:13
'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase.
AID1443991Induction of mitochondrial dysfunction in Sprague-Dawley rat liver mitochondria assessed as inhibition of mitochondrial respiration per mg mitochondrial protein measured for 20 mins by A65N-1 oxygen probe based fluorescence assay2014Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
AID239347Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand2005Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
AID177105ED50 value for catalepsy indicates the dose required to produce a 50% of maximum catalepsy score1992Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
Pyrrole mannich bases as potential antipsychotic agents.
AID1079931Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source]
AID1148008Binding affinity to bovine serum albumin assessed as intrinsic binding constant1977Journal of medicinal chemistry, Mar, Volume: 20, Issue:3
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
AID324491Increase in light chain 3-GFP+ autophagosome vesicle area per cell in human H4 cells at 8.3 uM after 24 hrs by high throughput fluorescence microscopy relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID1245901Binding affinity to dopamine D4 receptor (unknown origin) at 0.1 mM by radioligand displacement assay relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID92844Concentration required to inhibit ADP-induced platelet aggregation by 50%1992Journal of medicinal chemistry, Aug-07, Volume: 35, Issue:16
Molecular determinants of the platelet aggregation inhibitory activity of carbamoylpiperidines.
AID1079932Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source]
AID1245908Toxicity in mouse assessed as induction of lethargy at 10 mg/kg relative to control2015Bioorganic & medicinal chemistry, Oct-01, Volume: 23, Issue:19
Reengineered tricyclic anti-cancer agents.
AID337049Antiinflammatory activity in fMLP/cytochalasin B stimulated rat neutrophils assessed as inhibition of lysozyme release preincubated for 10 mins measured 45 mins after fMLP/cytochalasin B challenge2003Journal of natural products, Mar, Volume: 66, Issue:3
Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida.
AID625283Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID178517Inhibition of conditioned avoidance response (CAR)1986Journal of medicinal chemistry, Mar, Volume: 29, Issue:3
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
AID496819Antimicrobial activity against Plasmodium falciparum2010Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
AID264906Formation of PMA-induced superoxide in Sprague-Dawley rat neutrophil at 1 uM per 10^6 cells after 30 min2006Bioorganic & medicinal chemistry letters, May-15, Volume: 16, Issue:10
Synthesis of (2E)-3-{2-[(substituted benzyl)oxy]phenyl}acrylaldehydes as novel anti-inflammatory agents.
AID625285Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID324574Increase in FYVE-RFP+ vesicle intensity per cell in human H4 cells after 8 hrs relative to control2007Proceedings of the National Academy of Sciences of the United States of America, Nov-27, Volume: 104, Issue:48
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
AID295644Displacement of [3H]ketanserin from 5HT2A receptor at 10 uM2007Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID1745854NCATS anti-infectives library activity on HEK293 viability as a counter-qHTS vs the C. elegans viability qHTS2023Disease models & mechanisms, 03-01, Volume: 16, Issue:3
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
AID1347411qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1745855NCATS anti-infectives library activity on the primary C. elegans qHTS viability assay2023Disease models & mechanisms, 03-01, Volume: 16, Issue:3
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID1346893Human 5-HT2C receptor (5-Hydroxytryptamine receptors)2003Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Mar, Volume: 28, Issue:3
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
AID1345788Human D2 receptor (Dopamine receptors)2003Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Mar, Volume: 28, Issue:3
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
AID624223Antagonists at Human 5-Hydroxytryptamine receptor 5-HT2A2003Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Mar, Volume: 28, Issue:3
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
AID1259419Human 5-HT2A receptor (5-Hydroxytryptamine receptors)2003Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Mar, Volume: 28, Issue:3
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
AID1346037Human H1 receptor (Histamine receptors)2003Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Mar, Volume: 28, Issue:3
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
AID1345814Human D4 receptor (Dopamine receptors)1997Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Feb, Volume: 16, Issue:2
Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors.
AID1345788Human D2 receptor (Dopamine receptors)1997Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Feb, Volume: 16, Issue:2
Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (3,463)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902281 (65.87)18.7374
1990's685 (19.78)18.2507
2000's274 (7.91)29.6817
2010's178 (5.14)24.3611
2020's45 (1.30)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials157 (4.25%)5.53%
Reviews73 (1.98%)6.00%
Case Studies165 (4.46%)4.05%
Observational0 (0.00%)0.25%
Other3,301 (89.31%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Atypical Antipsychotics and Hyperglycemic Emergencies: Multicentre, Retrospective Cohort Study of Administrative Data[NCT02582736]725,489 participants (Actual)Observational2012-04-30Completed
A 12-Month Randomized, Open-Label Study of Caregiver Psycho-education and Skills Training in Patients Recently Diagnosed With Schizophrenia, Schizoaffective Disorder, or Schizophreniform Disorder and Receiving Paliperidone Palmitate or Oral Antipsychotic [NCT02600741]296 participants (Actual)Observational2015-07-24Completed
Randomized Multicentric Open-label Phase III Clinical Trial to Evaluate the Efficacy of Continual Treatment Versus Discontinuation Based in the Presence of Prodromes in a First Episode of Non-affective Psychosis.[NCT01765829]Phase 3104 participants (Anticipated)Interventional2012-11-30Recruiting
Phase I/II, Open Label Study to Determine Safety of Trifluoperazine (TFP) in Adults With Red Blood Cell Transfusion-Dependent Diamond Blackfan Anemia[NCT03966053]Phase 1/Phase 22 participants (Actual)Interventional2019-09-13Terminated(stopped due to Supporter terminated study due to slow subject accrual secondary to COVID pandemic limiting travel to research site.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Treatment-related Adverse Events as Assessed by the Simpson-Angus Scale and CTCAE v4.0

"Each subject will undergo weekly safety assessment using the Simpson-Angus Extrapyramidal Side Effects Scale to determine the safety of TFP in this new population of patients. The subjects will also undergo weekly bloodwork to evaluate for any liver or kidney abnormalities as well as a complete blood count and reticulocyte count. All dosed subjects will be followed for an additional 1 week after discontinuing study drug (post-study safety follow-up). There will be no more than 6 subjects enrolled at any particular time.~Treatment will be discontinued for any subject if their Hb is > 12 gm/dL , and not associated with RBC transfusions." (NCT03966053)
Timeframe: The subjects will be evaluated weekly for 4 weeks after the start of the 21-day course, 3 weeks while on the study drug and one week after completion.

InterventionParticipants (Count of Participants)
Cohort A0

SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
chlorpromazine[no description available]high72838organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
chlorpromazine[no description available]high7280organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
fluphenazine[no description available]high17614N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
fluphenazine[no description available]high1760N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
mesoridazine[no description available]high40phenothiazines;
sulfoxide;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic
perazine[no description available]high50N-alkylpiperazine;
N-methylpiperazine;
phenothiazines		dopaminergic antagonist;
phenothiazine antipsychotic drug
periciazine[no description available]medium40hydroxypiperidine;
nitrile;
phenothiazines		adrenergic antagonist;
first generation antipsychotic;
sedative
perphenazine[no description available]high1489N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
perphenazine[no description available]high1480N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
prochlorperazine[no description available]high1074N-alkylpiperazine;
N-methylpiperazine;
organochlorine compound;
phenothiazines		alpha-adrenergic antagonist;
antiemetic;
cholinergic antagonist;
dopamine receptor D2 antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic
prochlorperazine[no description available]high1070N-alkylpiperazine;
N-methylpiperazine;
organochlorine compound;
phenothiazines		alpha-adrenergic antagonist;
antiemetic;
cholinergic antagonist;
dopamine receptor D2 antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic
promazine[no description available]high882phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
promazine[no description available]high880phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
promethazine[no description available]high812phenothiazines;
tertiary amine		anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative
promethazine[no description available]high810phenothiazines;
tertiary amine		anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative
thioridazine[no description available]high21414phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
thioridazine[no description available]high2140phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
triflupromazine[no description available]high701organofluorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
triflupromazine[no description available]high700organofluorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
trimeprazine[no description available]high270phenothiazines
sulfaethidole[no description available]medium10benzenes;
sulfonamide
butaperazine[no description available]medium40phenothiazines
dixyrazine[no description available]medium20phenothiazines
methopromazine[no description available]medium10phenothiazines
1-(2-methoxyphenyl)piperazine[no description available]medium20piperazines
buspirone[no description available]high130azaspiro compound;
N-alkylpiperazine;
N-arylpiperazine;
organic heteropolycyclic compound;
piperidones;
pyrimidines		anxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
haloperidol[no description available]high22218aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
haloperidol[no description available]high2220aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
risperidone[no description available]high2111,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
risperidone[no description available]high2101,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
ritanserin[no description available]high20organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
levosulpiride[no description available]medium10sulpirideantidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
clozapine[no description available]high400benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
propranolol[no description available]medium500naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
propranolol[no description available]medium502naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
8-hydroxy-2-(di-n-propylamino)tetralin[no description available]medium10phenols;
tertiary amino compound;
tetralins		serotonergic antagonist
1-(3-chlorophenyl)piperazine[no description available]medium10monochlorobenzenes;
N-arylpiperazine		drug metabolite;
environmental contaminant;
serotonergic agonist;
xenobiotic
desipramine[no description available]medium390dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
desipramine[no description available]medium391dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
diazepam[no description available]medium5601,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
diazepam[no description available]medium5631,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
1-(3-trifluoromethylphenyl)piperazine[no description available]medium10(trifluoromethyl)benzenes;
N-arylpiperazine		environmental contaminant;
psychotropic drug;
serotonergic agonist;
xenobiotic
lysergic acid diethylamide[no description available]medium80ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
lysergic acid diethylamide[no description available]medium81ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
phencyclidine[no description available]medium50benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
phenylpiperazine[no description available]medium10
6-chloro-2-(1-piperazinyl)pyrazine[no description available]medium10N-arylpiperazine
atropine[no description available]medium350
cocaine[no description available]medium90benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
quinacrine[no description available]high340acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
gallopamil[no description available]medium150benzenes;
organic amino compound
4-aminopyridine[no description available]medium40aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
phenytoin[no description available]medium290imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
phenytoin[no description available]medium292imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
8-(4-sulfophenyl)theophylline[no description available]medium10
8-phenyltheophylline[no description available]medium20
theophylline[no description available]medium440dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
amitriptyline[no description available]medium680carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
amitriptyline[no description available]medium683carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
anisindione[no description available]medium10aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
baclofen[no description available]medium50amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
benzocaine[no description available]medium40benzoate ester;
substituted aniline		allergen;
antipruritic drug;
sensitiser;
topical anaesthetic
bepridil[no description available]medium180pyrrolidines;
tertiary amine		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
biperiden[no description available]medium70piperidines;
tertiary alcohol;
tertiary amino compound		antidote to sarin poisoning;
antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist;
parasympatholytic
biperiden[no description available]medium71piperidines;
tertiary alcohol;
tertiary amino compound		antidote to sarin poisoning;
antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist;
parasympatholytic
bupivacaine[no description available]medium40aromatic amide;
piperidinecarboxamide;
tertiary amino compound
butacaine[no description available]medium30benzoate ester
butamben[no description available]medium20amino acid ester;
benzoate ester;
primary amino compound;
substituted aniline		local anaesthetic
caffeine[no description available]medium380purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
verapamil[no description available]medium1990aromatic ether;
nitrile;
polyether;
tertiary amino compound
verapamil[no description available]medium1992aromatic ether;
nitrile;
polyether;
tertiary amino compound
carbamazepine[no description available]medium190dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
carbamazepine[no description available]medium191dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
chlordiazepoxide[no description available]medium580benzodiazepine
chlordiazepoxide[no description available]medium583benzodiazepine
chlorpheniramine[no description available]medium60monochlorobenzenes;
pyridines;
tertiary amino compound		anti-allergic agent;
antidepressant;
antipruritic drug;
H1-receptor antagonist;
histamine antagonist;
serotonin uptake inhibitor
cimetidine[no description available]medium110aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
clomipramine[no description available]high180dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor
cyproheptadine[no description available]medium60piperidines;
tertiary amine		anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist
diazoxide[no description available]medium40benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent
dibucaine[no description available]medium250aromatic ether;
monocarboxylic acid amide;
tertiary amino compound		topical anaesthetic
dicyclomine[no description available]medium40carboxylic ester;
tertiary amine		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
diphenidol[no description available]medium10benzenes;
piperidines;
tertiary alcohol		antiemetic
dilazep[no description available]medium20benzoate ester;
diazepane;
diester;
methoxybenzenes		cardioprotective agent;
platelet aggregation inhibitor;
vasodilator agent
diphenhydramine[no description available]high140ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
dipyridamole[no description available]medium100piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
doxepin[no description available]medium150dibenzooxepine;
tertiary amino compound		antidepressant
droperidol[no description available]high80aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
etazolate[no description available]medium10ethyl ester;
hydrazone;
pyrazolopyridine		alpha-secretase activator;
antidepressant;
antipsychotic agent;
anxiolytic drug;
GABA agent;
neuroprotective agent;
phosphodiesterase IV inhibitor
felodipine[no description available]medium100dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
flufenamic acid[no description available]medium30aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
flumazenil[no description available]high80ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
hydroxyzine[no description available]high130hydroxyether;
monochlorobenzenes;
N-alkylpiperazine		anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist
lidocaine[no description available]medium210benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
ici 118551[no description available]medium10indanes
imipramine[no description available]medium1300dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
imipramine[no description available]medium1306dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
indomethacin[no description available]medium420aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
1-methyl-3-isobutylxanthine[no description available]medium4003-isobutyl-1-methylxanthine
loperamide[no description available]medium120monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
mepivacaine[no description available]medium30piperidinecarboxamidedrug allergen;
local anaesthetic
benzoic acid [2-methyl-2-(propylamino)propyl] ester[no description available]medium20benzoate ester
metoprolol[no description available]medium70aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
mianserin[no description available]medium70dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist
nifedipine[no description available]medium740C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nisoldipine[no description available]medium60C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester
nitrendipine[no description available]medium100C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
nortriptyline[no description available]medium180organic tricyclic compound;
secondary amine		adrenergic uptake inhibitor;
analgesic;
antidepressant;
antineoplastic agent;
apoptosis inducer;
drug metabolite
nortriptyline[no description available]medium181organic tricyclic compound;
secondary amine		adrenergic uptake inhibitor;
analgesic;
antidepressant;
antineoplastic agent;
apoptosis inducer;
drug metabolite
oxethazaine[no description available]medium30amino acid amide
benoxinate[no description available]medium30amino acid ester;
benzoate ester;
substituted aniline;
tertiary amino compound		drug allergen;
local anaesthetic;
topical anaesthetic
papaverine[no description available]medium160benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
pentobarbital[no description available]medium170barbituratesGABAA receptor agonist
pheniramine[no description available]medium20pyridines;
tertiary amino compound
phenobarbital[no description available]medium280barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
phenobarbital[no description available]medium282barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
phenoxybenzamine[no description available]medium140aromatic amine
practolol[no description available]medium40acetamides;
ethanolamines;
propanolamine;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
beta-adrenergic antagonist
pramoxine[no description available]medium10aromatic ether;
morpholines		local anaesthetic
prazosin[no description available]medium100aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
prilocaine[no description available]medium10amino acid amide;
monocarboxylic acid amide		anticonvulsant;
local anaesthetic
proadifen[no description available]medium70diarylmethane
procainamide[no description available]medium40benzamidesanti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker
procaine[no description available]medium140benzoate ester;
substituted aniline;
tertiary amino compound		central nervous system depressant;
drug allergen;
local anaesthetic;
peripheral nervous system drug
proxymetacaine[no description available]medium10benzoate ester
protriptyline[no description available]medium40carbotricyclic compoundantidepressant
pyrilamine[no description available]medium80aromatic ether;
ethylenediamine derivative		H1-receptor antagonist
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone[no description available]medium40methoxybenzenes
rolipram[no description available]medium30pyrrolidin-2-onesantidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
secobarbital[no description available]medium40barbituratesanaesthesia adjuvant;
GABA modulator;
sedative
sotalol[no description available]medium50ethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide		anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
spiperone[no description available]high150aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
tetracaine[no description available]medium80benzoate ester;
tertiary amino compound		local anaesthetic
trazodone[no description available]high90monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazolopyridine		adrenergic antagonist;
antidepressant;
anxiolytic drug;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
trequinsin[no description available]medium10pyridopyrimidine
reserpine[no description available]medium590alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
reserpine[no description available]medium594alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
phentolamine[no description available]medium240imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
hexobendine[no description available]medium10trihydroxybenzoic acid
dichloroisoproterenol[no description available]medium20
tetraethylammonium chloride[no description available]medium10organic chloride salt;
quaternary ammonium salt		potassium channel blocker
tetrabenazine[no description available]medium120benzoquinolizine;
cyclic ketone;
tertiary amino compound
tetrabenazine[no description available]medium121benzoquinolizine;
cyclic ketone;
tertiary amino compound
piperoxan[no description available]medium30
nifenalol[no description available]medium10C-nitro compound
brompheniramine[no description available]medium30organobromine compound;
pyridines		anti-allergic agent;
H1-receptor antagonist
propoxycaine[no description available]medium10benzoate ester
dimethisoquin[no description available]medium20isoquinolines
parethoxycaine[no description available]medium10benzoate ester
yohimbine[no description available]medium40methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
2-chloroadenosine[no description available]medium10purine nucleoside
prenylamine[no description available]medium80diarylmethane
bicuculline[no description available]medium10benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
hexylcaine[no description available]medium10benzoate ester
piperocaine[no description available]medium10benzoate ester
diperodon[no description available]medium20carbamate ester
cyclomethycaine[no description available]medium10benzoate ester
carcainium chloride[no description available]medium10
azacyclonol[no description available]medium10diarylmethane
butoxamine[no description available]medium10
dexpropranolol[no description available]medium30propranolol
iprindole[no description available]medium50indoles
carticaine[no description available]medium10thiophenecarboxylic acid
timolol[no description available]medium50timololanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
butaclamol[no description available]medium10organic heteropentacyclic compound
etidocaine[no description available]medium10amino acid amidelocal anaesthetic
diltiazem[no description available]medium3305-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetateantihypertensive agent;
calcium channel blocker;
vasodilator agent
Arbaclofen[no description available]medium10organonitrogen compound;
organooxygen compound
colforsin[no description available]medium440acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
opromazine[no description available]medium70phenothiazines
corynanthine[no description available]medium10yohimban alkaloid
phenylisopropyladenosine[no description available]medium10aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent
w 7[no description available]medium10
2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene[no description available]medium10
rac 109[no description available]medium10
strychnine[no description available]medium30monoterpenoid indole alkaloid;
organic heteroheptacyclic compound		avicide;
cholinergic antagonist;
glycine receptor antagonist;
neurotransmitter agent;
rodenticide
quinidine[no description available]medium230cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
diethylstilbestrol[no description available]medium60olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
rauwolscine[no description available]medium10methyl 17-hydroxy-20xi-yohimban-16-carboxylate
chlorprothixene[no description available]medium390chlorprothixene
chlorprothixene[no description available]medium391chlorprothixene
flunarizine[no description available]medium140diarylmethane
thiothixene[no description available]medium80N-methylpiperazineanticoronaviral agent
cinnarizine[no description available]high50diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
quinine[no description available]medium230cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic
codeine[no description available]medium60morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
morphine[no description available]medium270morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
levorphanol[no description available]medium30morphinane alkaloid
dextrorphan[no description available]medium10morphinane alkaloid
zimeldine[no description available]medium40styrenes
1-methyl-d-lysergic acid butanolamide[no description available]medium50ergot alkaloid;
monocarboxylic acid amide		serotonergic antagonist;
sympatholytic agent;
vasoconstrictor agent
scopolamine hydrobromide[no description available]medium90
benzene[no description available]medium30aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
benzophenone[no description available]medium10benzophenonesphotosensitizing agent;
plant metabolite
tilorone[no description available]medium10aromatic ether;
diether;
fluoren-9-ones;
tertiary amino compound		anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist
nitrobenzene[no description available]medium20nitroarene;
nitrobenzenes
anisole[no description available]medium20monomethoxybenzeneplant metabolite
chlorobenzene[no description available]medium20monochlorobenzenessolvent
acridines[no description available]medium110acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
acridines[no description available]medium113acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
dextropropoxyphene[no description available]medium401-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoatemu-opioid receptor agonist;
opioid analgesic
fluanisone[no description available]medium10aromatic ketone
acetophenazine[no description available]high50N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
phenothiazines		phenothiazine antipsychotic drug
indoramin[no description available]medium20tryptamines
chlorfenethazine[no description available]medium30phenothiazines
emodin[no description available]medium20trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor
resveratrol[no description available]medium20resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
cis-resveratrol[no description available]medium10resveratrol
polydatin[no description available]medium20beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		anti-arrhythmia drug;
antioxidant;
geroprotector;
hepatoprotective agent;
metabolite;
nephroprotective agent;
potassium channel modulator
3,5,4'-trihydroxystilbene-4'-o-glucoside[no description available]medium10
loxapine[no description available]high146dibenzooxazepineantipsychotic agent;
dopaminergic antagonist
loxapine[no description available]high140dibenzooxazepineantipsychotic agent;
dopaminergic antagonist
sertindole[no description available]medium20heteroarylpiperidine;
imidazolidinone;
organochlorine compound;
organofluorine compound;
phenylindole		alpha-adrenergic antagonist;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic antagonist
acepromazine[no description available]high90aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound		phenothiazine antipsychotic drug
phenothiazine[no description available]medium830phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger
chloracizine[no description available]medium10
propionylpromazine[no description available]medium10
norchlorpromazine[no description available]medium20phenothiazines
didemethylchlorpromazine[no description available]medium30phenothiazines
7-hydroxychlorpromazine[no description available]medium10phenothiazines
chlorproethazine[no description available]medium10phenothiazines
chlorprothixene[no description available]medium10chlorprothixene
flupenthixol[no description available]medium30flupenthixoldopaminergic antagonist
zuclopenthixol[no description available]medium10clopenthixolalpha-adrenergic antagonist;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
thiophene-2-carboxaldehyde[no description available]medium10aldehyde;
thiophenes		metabolite
staurosporine[no description available]medium30indolocarbazole alkaloid;
organic heterooctacyclic compound		apoptosis inducer;
bacterial metabolite;
EC 2.7.11.13 (protein kinase C) inhibitor;
geroprotector
alpha-terthienyl[no description available]medium10terthiophene
4-hydroxybenzoic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
plant metabolite
benzoic acid[no description available]medium50benzoic acidsalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
benzyl alcohol[no description available]medium10benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
butyric acid[no description available]medium20fatty acid 4:0;
straight-chain saturated fatty acid		human urinary metabolite;
Mycoplasma genitalium metabolite
salicylic acid[no description available]medium50monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
gallic acid[no description available]medium500trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
octanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite
4-aminophenol[no description available]medium20aminophenolallergen;
metabolite
hydroquinone[no description available]medium20benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
methanol[no description available]medium60alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
n,n-dimethylaniline[no description available]medium10dimethylaniline;
tertiary amine
4-nitrophenol[no description available]medium304-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
phenol[no description available]medium30phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
pyrogallol[no description available]medium20benzenetriol;
phenolic donor		plant metabolite
tryptophan[no description available]medium10alpha-amino acid;
amino acid zwitterion;
aminoalkylindole;
aromatic amino acid;
polar amino acid		Daphnia magna metabolite
vanillin[no description available]medium20benzaldehydes;
monomethoxybenzene;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite
catechin[no description available]medium10hydroxyflavan
menthol[no description available]medium10p-menthane monoterpenoid;
secondary alcohol		volatile oil component
2-aminofluorene[no description available]medium10
homovanillic acid[no description available]medium140guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
6-hydroxymelatonin[no description available]medium10acetamides;
tryptamines		metabolite;
mouse metabolite
oxyquinoline[no description available]medium20monohydroxyquinolineantibacterial agent;
antifungal agrochemical;
antiseptic drug;
iron chelator
acetaminophen[no description available]medium150acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
aspirin[no description available]medium120benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
beta-naphthoflavone[no description available]medium10extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound		aryl hydrocarbon receptor agonist
bumetanide[no description available]medium130amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
ciprofibrate[no description available]medium40cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
clofibrate[no description available]medium80aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
clofibric acid[no description available]medium10aromatic ether;
monocarboxylic acid;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist
4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide[no description available]medium10sulfonamide
4-cresol[no description available]medium20cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
danthron[no description available]medium20dihydroxyanthraquinoneapoptosis inducer;
plant metabolite
dapsone[no description available]medium70substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
decanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
anti-inflammatory agent;
antibacterial agent;
human metabolite;
plant metabolite;
volatile oil component
diflunisal[no description available]medium60monohydroxybenzoic acid;
organofluorine compound		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
valproic acid[no description available]medium110branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
doxylamine[no description available]medium30pyridines;
tertiary amine		anti-allergic agent;
antiemetic;
antitussive;
cholinergic antagonist;
H1-receptor antagonist;
histamine antagonist;
sedative
ethacrynic acid[no description available]medium50aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
fenoprofen[no description available]medium30monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
berotek[no description available]medium30resorcinols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent;
tocolytic agent
fluorescite[no description available]medium20benzoic acids;
cyclic ketone;
hydroxy monocarboxylic acid;
organic heterotricyclic compound;
phenols;
xanthene dye		fluorescent dye;
radioopaque medium
furosemide[no description available]medium170chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
ibuprofen[no description available]medium110monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
ketoprofen[no description available]medium80benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
ketotifen[no description available]medium70cyclic ketone;
olefinic compound;
organic heterotricyclic compound;
organosulfur heterocyclic compound;
piperidines;
tertiary amino compound		anti-asthmatic drug;
H1-receptor antagonist
labetalol[no description available]medium90benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound
lamotrigine[no description available]medium401,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic
lauric acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
antibacterial agent;
plant metabolite
lorazepam[no description available]medium80benzodiazepine
losartan[no description available]medium80biphenylyltetrazole;
imidazoles		angiotensin receptor antagonist;
anti-arrhythmia drug;
antihypertensive agent;
endothelin receptor antagonist
meperidine[no description available]medium70ethyl ester;
piperidinecarboxylate ester;
tertiary amino compound		antispasmodic drug;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic
mesalamine[no description available]medium40amino acid;
aromatic amine;
monocarboxylic acid;
monohydroxybenzoic acid;
phenols		non-steroidal anti-inflammatory drug
mexiletine[no description available]medium50aromatic ether;
primary amino compound		anti-arrhythmia drug
mitoxantrone[no description available]medium90dihydroxyanthraquinoneanalgesic;
antineoplastic agent
oxazepam[no description available]medium701,4-benzodiazepinone;
organochlorine compound		anxiolytic drug;
environmental contaminant;
xenobiotic
oxyphenbutazone[no description available]medium20phenols;
pyrazolidines		antimicrobial agent;
antineoplastic agent;
antipyretic;
drug metabolite;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite
aminosalicylic acid[no description available]medium60aminobenzoic acid;
phenols		antitubercular agent
phenolphthalein[no description available]medium10phenols
phenolsulfonphthalein[no description available]medium102,1-benzoxathiole;
arenesulfonate ester;
phenols;
sultone		acid-base indicator;
diagnostic agent;
two-colour indicator
phenylbutazone[no description available]medium70pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
probenecid[no description available]medium90benzoic acids;
sulfonamide		uricosuric drug
propofol[no description available]high70phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
propyl gallate[no description available]medium10trihydroxybenzoic acid
1,2,5,8-tetrahydroxy anthraquinone[no description available]medium10tetrahydroxyanthraquinoneEC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
salicylamide[no description available]medium20phenols;
salicylamides		antirheumatic drug;
non-narcotic analgesic
sulfadimethoxine[no description available]medium30aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfathiazole[no description available]medium301,3-thiazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
sulfinpyrazone[no description available]medium50pyrazolidines;
sulfoxide		uricosuric drug
suprofen[no description available]medium30aromatic ketone;
monocarboxylic acid;
thiophenes		antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
temazepam[no description available]medium30benzodiazepine
terfenadine[no description available]medium80diarylmethane
thonzylamine[no description available]medium10methoxybenzenes
tiaprofenic acid[no description available]medium10aromatic ketone;
monocarboxylic acid;
thiophenes		drug allergen;
non-steroidal anti-inflammatory drug
tripelennamine[no description available]medium10aromatic amine
zomepirac[no description available]medium40aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles		cardiovascular drug;
non-steroidal anti-inflammatory drug
corticosterone[no description available]medium5011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
estriol[no description available]medium3016alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid		estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite
2-aminophenol[no description available]medium10aminophenolbacterial metabolite
thyroxine[no description available]medium902-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
aldosterone[no description available]medium7011beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
tetrahydrocortisol[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3alpha-hydroxy steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone
prednisone[no description available]medium11011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug
tetrahydrocortisone[no description available]medium1021-hydroxy steroid
estrone[no description available]medium5017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
androsterone[no description available]medium1017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
etiocholanolone[no description available]medium1017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid		human metabolite;
mouse metabolite
dehydroepiandrosterone[no description available]medium3017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid		androgen;
human metabolite;
mouse metabolite
hydroxyacetylaminofluorene[no description available]medium102-acetamidofluorenes
triiodothyronine[no description available]medium1602-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
benz(a)anthracene[no description available]medium10ortho-fused polycyclic arene;
tetraphenes
chloramphenicol[no description available]medium70C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
ethinyl estradiol[no description available]medium4017-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
aniline[no description available]medium20anilines;
primary arylamine
desoxycorticosterone[no description available]medium2020-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
norethindrone[no description available]medium7017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol		progestin;
synthetic oral contraceptive
norethynodrel[no description available]medium10oxo steroid
17-alpha-hydroxyprogesterone[no description available]medium1017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin
ampicillin[no description available]medium20beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
alizarin[no description available]medium10dihydroxyanthraquinonechromophore;
dye;
plant metabolite
linalool[no description available]medium10monoterpenoid;
tertiary alcohol		antimicrobial agent;
fragrance;
plant metabolite;
volatile oil component
1,4-dihydroxyanthraquinone[no description available]medium10dihydroxyanthraquinonedye
cyclizine[no description available]high60N-alkylpiperazineantiemetic;
central nervous system depressant;
cholinergic antagonist;
H1-receptor antagonist;
local anaesthetic
2,6-dihydroxyanthraquinone[no description available]medium10dihydroxyanthraquinoneantimutagen;
plant metabolite
9,10-anthraquinone[no description available]medium20anthraquinone
thymol[no description available]medium40monoterpenoid;
phenols		volatile oil component
1-naphthol[no description available]medium10naphtholgenotoxin;
human xenobiotic metabolite
2-aminodiphenyl[no description available]medium10
2-phenylphenol[no description available]medium10hydroxybiphenylsantifungal agrochemical;
environmental food contaminant
quinoline[no description available]medium30azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinolines
2-naphthylamine[no description available]medium30naphthylaminecarcinogenic agent
4-biphenylamine[no description available]medium10aminobiphenylcarcinogenic agent
4-phenylphenol[no description available]medium10hydroxybiphenyls
benzidine[no description available]medium30biphenyls;
substituted aniline		carcinogenic agent
4,4'-dihydroxybiphenyl[no description available]medium10hydroxybiphenyls
propylparaben[no description available]medium10benzoate ester;
paraben;
phenols		antifungal agent;
antimicrobial agent
butylphen[no description available]medium20phenolsallergen
methylparaben[no description available]medium10parabenantifungal agent;
antimicrobial food preservative;
neuroprotective agent;
plant metabolite
4-isopropylphenol[no description available]medium10phenolsflavouring agent
4-hydroxyacetophenone[no description available]medium10monohydroxyacetophenonefungal metabolite;
mouse metabolite;
plant metabolite
4-benzylphenol[no description available]medium10
2-ethylhexanol[no description available]medium10primary alcoholplant metabolite;
volatile oil component
2,2,2-trichloroethanol[no description available]medium10chloroethanolmouse metabolite
anthrarufin[no description available]medium10dihydroxyanthraquinone
2-toluic acid[no description available]medium10methylbenzoic acidxenobiotic metabolite
ethyl-p-hydroxybenzoate[no description available]medium20ethyl ester;
paraben		antifungal agent;
antimicrobial food preservative;
phytoestrogen;
plant metabolite
3-tert-butyl-4-hydroxyanisole[no description available]medium10aromatic ether;
phenols		antioxidant;
human xenobiotic metabolite
1-naphthylamine[no description available]medium20naphthylaminehuman xenobiotic metabolite
2-naphthol[no description available]medium30naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
shikimic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid;
hydroxy monocarboxylic acid		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
citronellol[no description available]medium10monoterpenoidplant metabolite
hexanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		human metabolite;
plant metabolite
pregnenolone[no description available]medium4020-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid		human metabolite;
mouse metabolite
ditiocarb[no description available]medium30dithiocarbamic acidschelator;
copper chelator
mequinol[no description available]medium10methoxybenzenes;
phenols		metabolite
catechin[no description available]medium20catechinantioxidant;
plant metabolite
phenetidine[no description available]medium10aromatic ether;
primary amino compound;
substituted aniline		drug metabolite
4-hydroxyphenobarbital[no description available]medium10barbiturates
lithocholic acid[no description available]medium30bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite
chenodeoxycholic acid[no description available]medium70bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
epitestosterone[no description available]medium1017alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen antagonist;
human metabolite
chrysophanic acid[no description available]medium20dihydroxyanthraquinoneanti-inflammatory agent;
antiviral agent;
plant metabolite
carvacrol[no description available]medium10botanical anti-fungal agent;
p-menthane monoterpenoid;
phenols		agrochemical;
antimicrobial agent;
flavouring agent;
TRPA1 channel agonist;
volatile oil component
androstenediol[no description available]medium1017beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid		androgen;
human metabolite;
mouse metabolite;
radiation protective agent
dihydrotestosterone[no description available]medium1017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
1,2,3,4-tetrahydro-1-naphthalenol[no description available]medium10
4-iodophenol[no description available]medium10iodophenol
myristic acid[no description available]medium10long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol[no description available]medium10terpineol;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiparasitic agent;
apoptosis inducer;
plant metabolite;
volatile oil component
3-hydroxyflavone[no description available]medium20flavonols;
monohydroxyflavone
6-hydroxyquinoline[no description available]medium10monohydroxyquinoline
3-hydroxybiphenyl[no description available]medium10hydroxybiphenyls
diphenylamine[no description available]medium20aromatic amine;
bridged diphenyl fungicide;
secondary amino compound		antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger
alpha-naphthoflavone[no description available]medium10extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound		aryl hydrocarbon receptor agonist;
aryl hydrocarbon receptor antagonist;
EC 1.14.14.14 (aromatase) inhibitor
4-propylphenol[no description available]medium10alkylbenzene
hexafluoroisopropanol[no description available]medium10organofluorine compound;
secondary alcohol		drug metabolite
d-alpha tocopherol[no description available]medium50alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
fenchol[no description available]medium10
4-n-Butylphenol[no description available]medium10phenols
4-hydroxyazobenzene[no description available]medium10
4-nitrothiophenolate[no description available]medium10
5 alpha-androstane-3 alpha,17 beta-diol[no description available]medium10androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite
menthol[no description available]medium10p-menthan-3-olantipruritic drug;
antispasmodic drug;
antitussive
hydroxyphenytoin[no description available]medium10imidazolidine-2,4-dione;
phenols		metabolite
mono-(2-ethylhexyl)phthalate[no description available]medium20phthalic acid monoester
1-naphthalenemethanol[no description available]medium10naphthylmethanolmouse metabolite
butylated hydroxyanisole[no description available]medium10
3-hydroxybenzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arene
4-n-Pentylphenol[no description available]medium10phenols
9-hydroxybenzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arene
daunorubicin[no description available]medium170aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
n-phenylethanolamine[no description available]medium10aralkylamine
4-ethylphenol[no description available]medium20phenolsfungal xenobiotic metabolite
ursodeoxycholic acid[no description available]medium80bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
pregnanolone[no description available]medium203-hydroxy-5beta-pregnan-20-one;
3alpha-hydroxy steroid		human metabolite;
intravenous anaesthetic;
sedative
butylated hydroxytoluene[no description available]medium30phenolsantioxidant;
ferroptosis inhibitor;
food additive;
geroprotector
zidovudine[no description available]medium110azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
6-hydroxybenzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arene
dexibuprofen[no description available]medium10ibuprofennon-narcotic analgesic;
non-steroidal anti-inflammatory drug
benoxaprofen[no description available]medium701,3-benzoxazoles;
monocarboxylic acid;
monochlorobenzenes		antipsoriatic;
antipyretic;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
hepatotoxic agent;
nephrotoxin;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
protein kinase C agonist
2-hydroxybenzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arene
octyl gallate[no description available]medium20gallate esterfood antioxidant;
hypoglycemic agent;
plant metabolite
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol[no description available]medium10stilbenoid
2',7'-dichlorofluorescein[no description available]medium102-benzofuransfluorochrome
16-hydroxytestosterone[no description available]medium1016alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid;
C19-steroid;
diol;
secondary alcohol		androgen
2-methoxyestradiol[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
5,6,7,8-tetrahydro-1-naphthol[no description available]medium10tetralins
alfatradiol[no description available]medium1017alpha-hydroxy steroid;
3-hydroxy steroid;
estradiol		estrogen;
geroprotector
4-hydroxyquinoline[no description available]medium10monohydroxyquinoline;
quinolone
17-alpha-hydroxypregnenolone[no description available]medium1017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
hydroxypregnenolone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
5-(3-hydroxyphenyl)-5-phenylhydantoin[no description available]medium10
7-amino-4-methylcoumarin[no description available]medium107-aminocoumarinsfluorochrome
11-hydroxyprogesterone, (11alpha)-isomer[no description available]medium1011alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid
brexanolone[no description available]medium103-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative
3,5-diiodothyronine, (l)-isomer[no description available]medium10phenylalanine derivative
harmol hydrochloride[no description available]medium10
diosgenin[no description available]medium103beta-sterol;
hexacyclic triterpenoid;
sapogenin;
spiroketal		antineoplastic agent;
antiviral agent;
apoptosis inducer;
metabolite
sarsasapogenin, (3beta,5alpha,25r)-isomer[no description available]medium10sapogeningout suppressant;
plant metabolite
3 alpha,17 alpha-dihydroxy-5 beta-pregnan-20-one[no description available]medium1017alpha-hydroxy steroid;
20-oxo steroid;
3alpha-hydroxy steroid;
C21-steroid;
corticosteroid hormone		human urinary metabolite
2-methoxyestriol[no description available]medium10
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine[no description available]medium10hydroxylamine;
imidazopyridine		carcinogenic agent;
genotoxin;
human xenobiotic metabolite;
mouse metabolite;
mutagen;
neurotoxin;
rat metabolite
ecopipam[no description available]medium10benzazepine
ibuprofen, (r)-isomer[no description available]medium10ibuprofen
11-hydroxytestosterone[no description available]medium1011beta-hydroxy steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid;
C19-steroid		bacterial xenobiotic metabolite;
human xenobiotic metabolite;
marine metabolite
norbuprenorphine[no description available]medium10phenanthrenes
benzo(a)pyrene-3,6-quinol[no description available]medium10
naproxen[no description available]medium110methoxynaphthalene;
monocarboxylic acid		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
cortolone[no description available]medium1021-hydroxy steroid
carbocysteine[no description available]medium10L-cysteine thioether;
non-proteinogenic L-alpha-amino acid		mucolytic
cholic acid[no description available]medium1012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
5 alpha-androstane-3 beta,17 beta-diol[no description available]medium1017beta-hydroxy steroid;
3beta-hydroxy steroid;
androstane-3,17-diol		Daphnia magna metabolite;
human metabolite
cortol[no description available]medium1021-hydroxy steroid
21-hydroxypregnenolone[no description available]medium1021-hydroxy steroid;
hydroxypregnenolone;
primary alpha-hydroxy ketone		mouse metabolite
2-hydroxyestradiol[no description available]medium1017beta-hydroxy steroid;
2-hydroxy steroid		carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug
epietiocholanolone[no description available]medium1017-oxo steroid;
3beta-hydroxy steroid;
androstanoid		androgen;
animal metabolite;
human blood serum metabolite;
mouse metabolite;
rat metabolite
naringenin[no description available]medium20(2S)-flavan-4-one;
naringenin		expectorant;
plant metabolite
2-hydroxyestrone[no description available]medium102-hydroxy steroid;
catechols		human metabolite
epiandrosterone[no description available]medium1017-oxo steroid;
3beta-hydroxy steroid;
androstanoid		androgen;
human metabolite
naringin[no description available]medium10(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside		anti-inflammatory agent;
antineoplastic agent;
metabolite
1-alpha-terpineol[no description available]medium10alpha-terpineolplant metabolite
diprenorphine[no description available]medium10morphinane alkaloid
ergosterol[no description available]medium203beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
tretinoin[no description available]medium120retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
retinol[no description available]medium20retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
ferulic acid[no description available]medium10ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite
mycophenolic acid[no description available]medium402-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
geraniol[no description available]medium103,7-dimethylocta-2,6-dien-1-ol;
monoterpenoid;
primary alcohol		allergen;
fragrance;
plant metabolite;
volatile oil component
dienestrol[no description available]medium30
captax[no description available]medium10aryl thiol;
benzothiazoles		carcinogenic agent;
metabolite
chlorogenic acid[no description available]medium10cinnamate ester;
tannin		food component;
plant metabolite
sch 23390[no description available]medium10benzazepine
digitoxigenin[no description available]medium1014beta-hydroxy steroid;
3beta-hydroxy steroid
quercetin[no description available]medium707-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
bilirubin[no description available]medium50biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
apigenin[no description available]medium20trihydroxyflavoneantineoplastic agent;
metabolite
scopoletin[no description available]medium10hydroxycoumarinplant growth regulator;
plant metabolite
hymecromone[no description available]medium70hydroxycoumarinantineoplastic agent;
hyaluronic acid synthesis inhibitor
vitamin d 2[no description available]medium50hydroxy seco-steroid;
seco-ergostane;
vitamin D		bone density conservation agent;
nutraceutical;
plant metabolite;
rodenticide
cholecalciferol[no description available]medium10D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone		geroprotector;
human metabolite
esculetin[no description available]medium10hydroxycoumarinantioxidant;
plant metabolite;
ultraviolet filter
7-hydroxycoumarin[no description available]medium10hydroxycoumarinfluorescent probe;
food component;
plant metabolite
baicalein[no description available]medium20trihydroxyflavoneangiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger
chrysin[no description available]medium107-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite
fisetin[no description available]medium103'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite
galangin[no description available]medium207-hydroxyflavonol;
trihydroxyflavone		antimicrobial agent;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
plant metabolite
4-hydroxyestradiol[no description available]medium104-hydroxy steroidmetabolite
isotretinoin[no description available]medium70retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent
hyodeoxycholic acid[no description available]medium105beta-cholanic acids;
6alpha,20xi-murideoxycholic acid;
bile acid;
C24-steroid		human metabolite;
mouse metabolite
hydromorphone[no description available]medium30morphinane alkaloid;
organic heteropentacyclic compound		mu-opioid receptor agonist;
opioid analgesic
nalmefene[no description available]medium40morphinane alkaloid
nalorphine[no description available]medium20morphinane alkaloid
naloxone[no description available]medium80morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
oxycodone[no description available]medium20organic heteropentacyclic compound;
semisynthetic derivative		antitussive;
mu-opioid receptor agonist;
opioid analgesic
oxymorphone[no description available]medium20morphinane alkaloid
6alpha-hydroxy-17beta-estradiol[no description available]medium106alpha-hydroxy steroid
nalbuphine[no description available]medium30organic heteropentacyclic compoundmu-opioid receptor antagonist;
opioid analgesic
cinnamyl alcohol[no description available]medium10cinnamyl alcoholplant metabolite
naltrexone[no description available]medium70cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic
normorphine[no description available]medium10morphinane alkaloid
naltrindole benzofuran[no description available]medium10morphinane alkaloid
naltrindole[no description available]medium10isoquinolines
19-hydroxycholesterol[no description available]medium10cholestanoid
borneol[no description available]medium10borneol
norcodeine[no description available]medium10morphinane alkaloid
4-hydroxyestrone[no description available]medium1017-oxo steroid;
3-hydroxy steroid;
4-hydroxy steroid;
catechols;
phenolic steroid		carcinogenic agent;
estrogen;
human urinary metabolite
11 beta-hydroxyandrosterone[no description available]medium103-hydroxy steroidandrogen
2-hydroxyestriol[no description available]medium10
novobiocin[no description available]medium40carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
tetracycline[no description available]medium100
4-hydroxycoumarin[no description available]medium10hydroxycoumarin
rifampin[no description available]medium90cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
norclozapine[no description available]medium20dibenzodiazepine;
organochlorine compound;
piperazines		delta-opioid receptor agonist;
metabolite;
serotonergic antagonist
ethylene dichloride[no description available]medium30chloroethaneshepatotoxic agent;
mutagen;
non-polar solvent
acetamide[no description available]medium10acetamides;
carboximidic acid;
monocarboxylic acid amide;
N-acylammonia
adenine[no description available]medium706-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
benzaldehyde[no description available]medium10benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
propionaldehyde[no description available]medium10alpha-CH2-containing aldehyde;
propanals		Escherichia coli metabolite
dibenzofuran[no description available]medium10dibenzofurans;
mancude organic heterotricyclic parent;
polycyclic heteroarene		xenobiotic
cytosine[no description available]medium10aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
alanine[no description available]medium10alpha-amino acid;
amino acid zwitterion		fundamental metabolite
hexachlorocyclohexane[no description available]medium30chlorocyclohexane
indole[no description available]medium20indole;
polycyclic heteroarene		Escherichia coli metabolite
acetanilide[no description available]medium20acetamides;
anilide		analgesic
naphthalene[no description available]medium10naphthalenes;
ortho-fused bicyclic arene		apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component
1-propanol[no description available]medium40propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
pyridine[no description available]medium30azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
dimethyl sulfide[no description available]medium10aliphatic sulfidealgal metabolite;
bacterial xenobiotic metabolite;
EC 3.5.1.4 (amidase) inhibitor;
Escherichia coli metabolite;
marine metabolite
succinic acid[no description available]medium10alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
toluene[no description available]medium20methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
trimethylamine[no description available]medium10methylamines;
tertiary amine		Escherichia coli metabolite;
human xenobiotic metabolite
uracil[no description available]medium20pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
atrazine[no description available]medium20chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
barbital[no description available]medium20barbituratesdrug allergen
benzamide[no description available]medium20benzamides
bay h 4502[no description available]medium30biphenyls;
imidazoles
bromazepam[no description available]medium10organic molecular entity
ddt[no description available]medium40benzenoid aromatic compound;
chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide		bridged diphenyl acaricide;
carcinogenic agent;
endocrine disruptor;
persistent organic pollutant
diuron[no description available]medium303-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene		environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic
ether[no description available]medium30ether;
volatile organic compound		inhalation anaesthetic;
non-polar solvent;
refrigerant
fenbufen[no description available]medium104-oxo monocarboxylic acid;
biphenyls		non-steroidal anti-inflammatory drug
fluconazole[no description available]medium90conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
flurbiprofen[no description available]medium90fluorobiphenyl;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
indoprofen[no description available]medium10gamma-lactam;
isoindoles;
monocarboxylic acid		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
2-propanol[no description available]medium20secondary alcohol;
secondary fatty alcohol		protic solvent
nevirapine[no description available]medium60cyclopropanes;
dipyridodiazepine		antiviral drug;
HIV-1 reverse transcriptase inhibitor
phenacetin[no description available]medium60acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
mannitol[no description available]medium80mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
4-toluenesulfonamide[no description available]medium10sulfonamide
1,1,1-trichloroethane[no description available]medium20chloroethanespolar solvent
ethylamine[no description available]medium20primary aliphatic aminehuman metabolite
nitromethane[no description available]medium10primary nitroalkane;
volatile organic compound		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
explosive;
NMR chemical shift reference compound;
polar aprotic solvent
tert-butyl alcohol[no description available]medium10tertiary alcoholhuman xenobiotic metabolite
methylethyl ketone[no description available]medium20butanone;
dialkyl ketone;
methyl ketone;
volatile organic compound		bacterial metabolite;
polar aprotic solvent
trichloroethylene[no description available]medium50chloroethenesinhalation anaesthetic;
mouse metabolite
methyl acetate[no description available]medium10acetate ester;
methyl ester;
volatile organic compound		EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
fragrance;
polar aprotic solvent
nitroethane[no description available]medium10primary nitroalkane
fluorene[no description available]medium20ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon
hexamethylbenzene[no description available]medium10methylbenzene
diphenyl[no description available]medium10aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative
methyl benzoate[no description available]medium10benzoate ester;
methyl ester		insect attractant;
metabolite
benzotrifluoride[no description available]medium10(trifluoromethyl)benzenes;
fluorohydrocarbon		environmental contaminant;
NMR chemical shift reference compound;
solvent
acetophenone[no description available]medium10acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
carvone[no description available]medium10botanical anti-fungal agent;
carvones		allergen
benzonitrile[no description available]medium10benzenes;
nitrile
4-chloroaniline[no description available]medium10chloroaniline;
monochlorobenzenes
propionitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		polar aprotic solvent
bromobenzene[no description available]medium30bromoarene;
bromobenzenes;
volatile organic compound		hepatotoxic agent;
mouse metabolite;
non-polar solvent
pentane[no description available]medium20alkane;
volatile organic compound		non-polar solvent;
refrigerant
dimethoxymethane[no description available]medium10acetal;
diether
tetrahydrofuran[no description available]medium10cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
furan[no description available]medium10furans;
mancude organic heteromonocyclic parent;
monocyclic heteroarene		carcinogenic agent;
hepatotoxic agent;
Maillard reaction product
thiophenes[no description available]medium10mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
n-hexane[no description available]medium30alkane;
volatile organic compound		neurotoxin;
non-polar solvent
cyclohexane[no description available]medium30cycloalkane;
volatile organic compound		non-polar solvent
cyclohexene[no description available]medium10cycloalkene
morpholine[no description available]medium10morpholines;
saturated organic heteromonocyclic parent		NMR chemical shift reference compound
3-nitrobenzoic acid[no description available]medium10
ethyl acetate[no description available]medium20acetate ester;
ethyl ester;
volatile organic compound		EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
metabolite;
polar aprotic solvent;
Saccharomyces cerevisiae metabolite
ephedrine[no description available]medium50phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
fluorobenzenes[no description available]medium10monofluorobenzenesNMR chemical shift reference compound
4-chloroacetanilide[no description available]medium10acetamides;
monochlorobenzenes
1-chloropropane[no description available]medium10
2,3-dichlorophenol[no description available]medium10
methyl butyrate[no description available]medium10fatty acid ester
decachlorobiphenyl[no description available]medium10pentachlorobenzenes;
polychlorobiphenyl
desmedipham[no description available]medium10carbamate esteragrochemical;
environmental contaminant;
herbicide;
xenobiotic
menthone[no description available]medium10menthone
dimethylacetamide[no description available]medium10acetamides;
monocarboxylic acid amide		human metabolite
pyrene[no description available]medium20ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
fenoxycarb[no description available]medium10aromatic ether;
carbamate ester		environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic
fenclofenac[no description available]medium20aromatic ether
camphora[no description available]medium10camphor
(+)-limonene[no description available]medium30limoneneplant metabolite
griseofulvin[no description available]medium601-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite
sulindac[no description available]medium90monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent
dinoprostone[no description available]medium350prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
nifuroxime[no description available]medium20
nitrofurantoin[no description available]medium80imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
warfarin[no description available]medium140benzenes;
hydroxycoumarin;
methyl ketone
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
allopurinol[no description available]medium200nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
2-benzyloxybenzaldehyde[no description available]medium20
carvedilol[no description available]medium30carbazoles;
secondary alcohol;
secondary amino compound		alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent
clofazimine[no description available]medium30monochlorobenzenes;
phenazines		dye;
leprostatic drug;
non-steroidal anti-inflammatory drug
itraconazole[no description available]medium50piperazines
ketoconazole[no description available]medium170dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
nicardipine[no description available]medium200benzenes;
C-nitro compound;
diester;
dihydropyridine;
methyl ester;
tertiary amino compound
emetine[no description available]medium40isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
vinblastine[no description available]medium30
paclitaxel[no description available]medium150taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
lovastatin[no description available]medium90delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
simvastatin[no description available]medium80delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug
clarithromycin[no description available]medium60macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic
norgallopamil[no description available]medium10
tetraphenylphosphonium[no description available]medium50heteroorganic entity;
phosphorus molecular entity;
polyatomic cation
troleandomycin[no description available]medium30acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic
tamoxifen[no description available]medium440stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
cyclosporine[no description available]medium100homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite
amiodarone[no description available]medium1401-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
omeprazole[no description available]medium50aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
propafenone[no description available]medium60aromatic ketone;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug
dexverapamil[no description available]medium102-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrileEC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
pafenolol[no description available]medium10
lekoptin[no description available]medium202-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
norverapamil[no description available]medium10aromatic ether;
nitrile;
polyether;
secondary amino compound
quetiapine[no description available]high20dibenzothiazepine;
N-alkylpiperazine;
N-arylpiperazine		adrenergic antagonist;
dopaminergic antagonist;
histamine antagonist;
second generation antipsychotic;
serotonergic antagonist
pimozide[no description available]high5710benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
pimozide[no description available]high570benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
molindone[no description available]medium80indoles
molindone[no description available]medium83indoles
aripiprazole[no description available]high70aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone		drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist
ziprasidone[no description available]medium301,2-benzisothiazole;
indolones;
organochlorine compound;
piperazines		antipsychotic agent;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
psychotropic drug;
serotonergic antagonist
olanzapine[no description available]high133benzodiazepine;
N-arylpiperazine;
N-methylpiperazine		antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
serotonin uptake inhibitor
olanzapine[no description available]high130benzodiazepine;
N-arylpiperazine;
N-methylpiperazine		antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
serotonin uptake inhibitor
n-(3-(aminomethyl)benzyl)acetamidine[no description available]medium40aralkylamine;
carboxamidine;
primary amino compound		angiogenesis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector
4',7-dihydroxyflavone[no description available]medium10dihydroxyflavonemetabolite
2'-hydroxygenistein[no description available]medium10hydroxyisoflavoneplant metabolite
4,5,6,7-tetrabromo-2-azabenzimidazole[no description available]medium10
patulin[no description available]medium10furopyran;
gamma-lactone;
lactol		antimicrobial agent;
Aspergillus metabolite;
carcinogenic agent;
mutagen;
mycotoxin;
Penicillium metabolite
michler's ketone[no description available]medium10benzophenones
neutral red base[no description available]medium10aromatic amine;
phenazines;
primary amino compound;
tertiary amino compound		acid-base indicator;
dye;
two-colour indicator
epirubicin[no description available]medium60aminoglycoside;
anthracycline antibiotic;
anthracycline;
deoxy hexoside;
monosaccharide derivative;
p-quinones;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		antimicrobial agent;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
ribavirin 5'-triphosphate[no description available]medium101-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide;
ribose triphosphate		antiviral agent;
drug metabolite;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
eukaryotic initiation factor 4F inhibitor;
human blood serum metabolite
ribavirin 5'-diphosphate[no description available]medium101-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide;
ribose diphosphate		antiviral agent;
drug metabolite
4-phenyl-4-oxo-2-hydroxybuten-2-oic acid[no description available]medium10
biln 2061[no description available]medium10
buflomedil[no description available]medium10aromatic ketone
nafoxidine[no description available]medium20benzenes;
naphthalenes;
ring assembly
raloxifene[no description available]medium501-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
trifluperidol[no description available]medium180aromatic ketone
trifluperidol[no description available]medium186aromatic ketone
triparanol[no description available]medium20stilbenoidanticoronaviral agent
1,3-ditolylguanidine[no description available]medium10toluenes
opipramol[no description available]medium20dibenzoazepine
opipramol[no description available]medium21dibenzoazepine
jervine[no description available]medium10piperidines
naftifine[no description available]medium20allylamine antifungal drug;
naphthalenes;
tertiary amine		EC 1.14.13.132 (squalene monooxygenase) inhibitor;
sterol biosynthesis inhibitor
carbizocaine[no description available]medium10
fenpropimorph[no description available]medium20alkylbenzene
preclamol[no description available]medium10
enclomiphene[no description available]medium30
zuclomiphene[no description available]medium10stilbenoid
terbinafine[no description available]medium60acetylenic compound;
allylamine antifungal drug;
enyne;
naphthalenes;
tertiary amine		EC 1.14.13.132 (squalene monooxygenase) inhibitor;
P450 inhibitor;
sterol biosynthesis inhibitor
bm 15766[no description available]medium10
ne 100[no description available]medium10
bupropion[no description available]medium60aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
aminocaproic acid[no description available]medium50amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite
tacrine[no description available]medium60acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor
acebutolol[no description available]medium50aromatic amide;
ethanolamines;
ether;
monocarboxylic acid amide;
propanolamine;
secondary amino compound		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympathomimetic agent
acetohydroxamic acid[no description available]medium30acetohydroxamic acids;
carbohydroximic acid		algal metabolite;
EC 3.5.1.5 (urease) inhibitor
albuterol[no description available]medium70phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
alendronate[no description available]medium501,1-bis(phosphonic acid);
primary amino compound		bone density conservation agent;
EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
alprazolam[no description available]medium60organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
alprazolam[no description available]medium61organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
altretamine[no description available]medium40triamino-1,3,5-triazine
amantadine[no description available]medium120adamantanes;
primary aliphatic amine		analgesic;
antiparkinson drug;
antiviral drug;
dopaminergic agent;
NMDA receptor antagonist;
non-narcotic analgesic
amantadine[no description available]medium122adamantanes;
primary aliphatic amine		analgesic;
antiparkinson drug;
antiviral drug;
dopaminergic agent;
NMDA receptor antagonist;
non-narcotic analgesic
amifostine anhydrous[no description available]medium30diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent
aminoglutethimide[no description available]medium60dicarboximide;
piperidones;
substituted aniline		adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
amlexanox[no description available]medium10monocarboxylic acid;
pyridochromene		anti-allergic agent;
anti-ulcer drug;
non-steroidal anti-inflammatory drug
amlodipine[no description available]medium50dihydropyridine;
ethyl ester;
methyl ester;
monochlorobenzenes;
primary amino compound		antihypertensive agent;
calcium channel blocker;
vasodilator agent
amoxapine[no description available]high80dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor
anastrozole[no description available]medium20nitrile;
triazoles		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
apraclonidine[no description available]medium10dichlorobenzene;
guanidines;
imidazolines		alpha-adrenergic agonist;
antiglaucoma drug;
beta-adrenergic agonist;
diagnostic agent;
ophthalmology drug
astemizole[no description available]medium60benzimidazoles;
piperidines		anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist
atenolol[no description available]medium100ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic
azathioprine[no description available]medium80aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug
azelaic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		antibacterial agent;
antineoplastic agent;
dermatologic drug;
plant metabolite
azelastine[no description available]medium10monochlorobenzenes;
phthalazines;
tertiary amino compound		anti-allergic agent;
anti-asthmatic drug;
bronchodilator agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
H1-receptor antagonist;
platelet aggregation inhibitor
betaxolol[no description available]medium40propanolamineantihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
bicalutamide[no description available]medium60(trifluoromethyl)benzenes;
monocarboxylic acid amide;
monofluorobenzenes;
nitrile;
sulfone;
tertiary alcohol
bisoprolol[no description available]medium50secondary alcohol;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
brimonidine[no description available]medium10imidazoles;
quinoxaline derivative;
secondary amine		adrenergic agonist;
alpha-adrenergic agonist;
antihypertensive agent
busulfan[no description available]medium60methanesulfonate esteralkylating agent;
antineoplastic agent;
carcinogenic agent;
insect sterilant;
teratogenic agent
butenafine[no description available]medium10naphthalenes;
tertiary amine		antifungal drug;
EC 1.14.13.132 (squalene monooxygenase) inhibitor
carmustine[no description available]medium40N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
carteolol[no description available]medium30quinolone;
secondary alcohol		anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
cetirizine[no description available]medium30ether;
monocarboxylic acid;
monochlorobenzenes;
piperazines		anti-allergic agent;
environmental contaminant;
H1-receptor antagonist;
xenobiotic
chlormezanone[no description available]medium301,3-thiazine;
lactam;
monochlorobenzenes;
sulfone		antipsychotic agent;
anxiolytic drug;
muscle relaxant
ciclopirox[no description available]medium30cyclic hydroxamic acid;
hydroxypyridone antifungal drug;
pyridone		antibacterial agent;
antiseborrheic
cinoxacin[no description available]medium10cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent
ciprofloxacin[no description available]medium70aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
cisapride[no description available]medium40benzamides
clonidine[no description available]medium150clonidine;
imidazoline
clonidine[no description available]medium152clonidine;
imidazoline
chlorazepate[no description available]medium301,4-benzodiazepinoneanticonvulsant;
anxiolytic drug;
GABA modulator;
prodrug
cyclobenzaprine[no description available]medium50carbotricyclic compoundantidepressant;
muscle relaxant;
tranquilizing drug
diclofenac[no description available]medium130amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
dipivefrin[no description available]medium10ethanolamines;
pivalate ester		adrenergic agonist;
antiglaucoma drug;
ophthalmology drug;
prodrug;
sympathomimetic agent
disopyramide[no description available]medium20monocarboxylic acid amide;
pyridines;
tertiary amino compound		anti-arrhythmia drug
disulfiram[no description available]medium90organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
doxazosin[no description available]medium40aromatic amine;
benzodioxine;
monocarboxylic acid amide;
N-acylpiperazine;
N-arylpiperazine;
quinazolines		alpha-adrenergic antagonist;
antihyperplasia drug;
antihypertensive agent;
antineoplastic agent;
vasodilator agent
econazole[no description available]medium40dichlorobenzene;
ether;
imidazoles;
monochlorobenzenes
enflurane[no description available]medium20ether;
organochlorine compound;
organofluorine compound		anaesthetic
enoxacin[no description available]medium101,8-naphthyridine derivative;
amino acid;
fluoroquinolone antibiotic;
monocarboxylic acid;
N-arylpiperazine;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor
estazolam[no description available]medium20triazoles;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA modulator
etidronate[no description available]medium701,1-bis(phosphonic acid)antineoplastic agent;
bone density conservation agent;
chelator
etodolac[no description available]medium30monocarboxylic acid;
organic heterotricyclic compound		antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
brl 42810[no description available]medium302-aminopurines;
acetate ester		antiviral drug;
prodrug
felbamate[no description available]medium60carbamate esteranticonvulsant;
neuroprotective agent
fenfluramine[no description available]medium20(trifluoromethyl)benzenes;
secondary amino compound		appetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
fentanyl[no description available]medium30anilide;
monocarboxylic acid amide;
piperidines		adjuvant;
anaesthesia adjuvant;
anaesthetic;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
fexofenadine[no description available]medium50piperidines;
tertiary amine		anti-allergic agent;
H1-receptor antagonist
flecainide[no description available]medium40aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines		anti-arrhythmia drug
flucytosine[no description available]medium50aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
fluorouracil[no description available]high90nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
fluoxetine[no description available]medium140(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound
fluphenazine depot[no description available]high40decanoate ester;
N-alkylpiperazine;
organofluorine compound;
phenothiazines		dopaminergic antagonist;
phenothiazine antipsychotic drug;
prodrug
fluphenazine enanthate[no description available]medium10phenothiazines
flutamide[no description available]medium80(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent
foscarnet[no description available]medium40carboxylic acid;
one-carbon compound;
phosphonic acids		antiviral drug;
geroprotector;
HIV-1 reverse transcriptase inhibitor;
sodium-dependent Pi-transporter inhibitor
gabapentin[no description available]medium50gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
gemfibrozil[no description available]medium50aromatic etherantilipemic drug
glimepiride[no description available]medium70sulfonamide
glipizide[no description available]medium20aromatic amide;
monocarboxylic acid amide;
N-sulfonylurea;
pyrazines		EC 2.7.1.33 (pantothenate kinase) inhibitor;
hypoglycemic agent;
insulin secretagogue
glyburide[no description available]medium70monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
granisetron[no description available]medium20aromatic amide;
indazoles
guanfacine[no description available]medium20acetamides
halothane[no description available]high70haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
hydrochlorothiazide[no description available]medium70benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
hydroxyurea[no description available]medium80one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
phenelzine[no description available]medium240primary amine
ifosfamide[no description available]medium60ifosfamidesalkylating agent;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
xenobiotic
amrinone[no description available]medium90bipyridinesEC 3.1.4.* (phosphoric diester hydrolase) inhibitor
indapamide[no description available]medium40indoles;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic
iodixanol[no description available]medium10organoiodine compoundradioopaque medium
iohexol[no description available]medium10benzenedicarboxamide;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
iopromide[no description available]medium10dicarboxylic acid diamide;
organoiodine compound		environmental contaminant;
nephrotoxic agent;
radioopaque medium;
xenobiotic
ioversol[no description available]medium20amidobenzoic acid
isoflurane[no description available]medium20organofluorine compoundinhalation anaesthetic
isoniazid[no description available]medium70carbohydrazideantitubercular agent;
drug allergen
isradipine[no description available]medium20benzoxadiazole;
dihydropyridine;
isopropyl ester;
methyl ester
ketorolac[no description available]medium30amino acid;
aromatic ketone;
monocarboxylic acid;
pyrrolizines;
racemate		analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
lansoprazole[no description available]medium40benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
lomefloxacin[no description available]medium30fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antimicrobial agent;
antitubercular agent;
photosensitizing agent
loratadine[no description available]medium40benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist
maprotiline[no description available]medium100anthracenes
mebendazole[no description available]medium50aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
meclofenamic acid[no description available]medium60aminobenzoic acid;
organochlorine compound;
secondary amino compound		analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
mefenamic acid[no description available]medium50aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
mefloquine hydrochloride[no description available]medium20organofluorine compound;
piperidines;
quinolines;
secondary alcohol
metformin[no description available]medium50guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
metoclopramide[no description available]high100benzamides;
monochlorobenzenes;
substituted aniline;
tertiary amino compound		antiemetic;
dopaminergic antagonist;
environmental contaminant;
gastrointestinal drug;
xenobiotic
metronidazole[no description available]medium60C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
midazolam[no description available]medium50imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
midodrine[no description available]medium20amino acid amide;
aromatic ether;
secondary alcohol		alpha-adrenergic agonist;
prodrug;
sympathomimetic agent;
vasoconstrictor agent
minoxidil[no description available]medium50dialkylarylamine;
tertiary amino compound
mirtazapine[no description available]medium40benzazepine;
tetracyclic antidepressant		alpha-adrenergic antagonist;
anxiolytic drug;
H1-receptor antagonist;
histamine antagonist;
oneirogen;
serotonergic antagonist
nabumetone[no description available]medium40methoxynaphthalene;
methyl ketone		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
nefazodone[no description available]medium70aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles		alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor
nilutamide[no description available]medium20(trifluoromethyl)benzenes;
C-nitro compound;
imidazolidinone		androgen antagonist;
antineoplastic agent
nimodipine[no description available]medium1302-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nizatidine[no description available]medium301,3-thiazoles;
C-nitro compound;
carboxamidine;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
cholinergic drug;
H2-receptor antagonist
masoprocol[no description available]medium10catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite
norfloxacin[no description available]medium50fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug;
DNA synthesis inhibitor;
environmental contaminant;
xenobiotic
ofloxacin[no description available]medium403-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline
ondansetron[no description available]medium20carbazoles
oxaprozin[no description available]medium401,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug
pamidronate[no description available]medium50phosphonoacetic acid
pemoline[no description available]medium501,3-oxazolescentral nervous system stimulant
pentamidine[no description available]high70aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
pentoxifylline[no description available]medium40oxopurine
pindolol[no description available]medium50indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
pirbuterol[no description available]medium10pyridines
prazepam[no description available]medium10benzodiazepine
praziquantel[no description available]medium100isoquinolines
primidone[no description available]medium90pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
primidone[no description available]medium91pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
procarbazine[no description available]medium30benzamides;
hydrazines		antineoplastic agent
sch 16134[no description available]medium20benzodiazepine
ranitidine[no description available]medium50aralkylamine
riluzole[no description available]medium50benzothiazoles
rimantadine[no description available]medium30alkylamine
salmeterol xinafoate[no description available]medium10ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound
sevoflurane[no description available]medium20ether;
organofluorine compound		central nervous system depressant;
inhalation anaesthetic;
platelet aggregation inhibitor
sulfadiazine[no description available]medium50pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
sulconazole[no description available]medium10dichlorobenzene;
imidazoles;
monochlorobenzenes;
organic sulfide
sulfasalazine[no description available]medium50
sumatriptan[no description available]medium50sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
tazarotene[no description available]medium10acetylenic compound;
ethyl ester;
pyridines;
retinoid;
thiochromane		keratolytic drug;
prodrug;
teratogenic agent
terazosin[no description available]medium20furans;
piperazines;
primary amino compound;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
antineoplastic agent
thiotepa[no description available]medium30aziridines
ticlopidine[no description available]medium80monochlorobenzenes;
thienopyridine		anticoagulant;
fibrin modulating drug;
hematologic agent;
P2Y12 receptor antagonist;
platelet aggregation inhibitor
tioconazole[no description available]medium10dichlorobenzene;
ether;
imidazoles;
thiophenes
tiopronin[no description available]medium20N-acyl-amino acid
tizanidine[no description available]medium20benzothiadiazole;
imidazoles		alpha-adrenergic agonist;
muscle relaxant
ultram[no description available]medium30aromatic ether;
tertiary alcohol;
tertiary amino compound
triazolam[no description available]medium40triazolobenzodiazepinesedative
trientine[no description available]medium10polyazaalkane;
tetramine		copper chelator
trimethadione[no description available]medium50oxazolidinoneanticonvulsant;
geroprotector
trimetrexate[no description available]medium20
trimipramine[no description available]medium40dibenzoazepine;
tertiary amino compound		antidepressant;
environmental contaminant;
xenobiotic
venlafaxine[no description available]medium50cyclohexanols;
monomethoxybenzene;
tertiary alcohol;
tertiary amino compound		adrenergic uptake inhibitor;
analgesic;
antidepressant;
dopamine uptake inhibitor;
environmental contaminant;
serotonin uptake inhibitor;
xenobiotic
ici 204,219[no description available]medium60carbamate ester;
indoles;
N-sulfonylcarboxamide		anti-asthmatic agent;
leukotriene antagonist
zolpidem[no description available]medium40imidazopyridinecentral nervous system depressant;
GABA agonist;
sedative
floxuridine[no description available]medium30nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
spironolactone[no description available]medium503-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
penicillamine[no description available]medium70non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
pilocarpine[no description available]medium80pilocarpineantiglaucoma drug
vincristine[no description available]medium30acetate ester;
formamides;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
testosterone propionate[no description available]medium10steroid ester
bretylium tosylate[no description available]medium10organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent
cytarabine[no description available]medium60beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
trifluridine[no description available]medium30nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
EC 2.1.1.45 (thymidylate synthase) inhibitor
medroxyprogesterone acetate[no description available]medium3020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester		adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive
mestranol[no description available]medium6017beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound		prodrug;
xenoestrogen
methylprednisolone[no description available]high606-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic
estradiol dipropionate[no description available]medium10steroid ester
nafcillin[no description available]medium20penicillin allergen;
penicillin		antibacterial drug
methohexital[no description available]medium30acetylenic compound;
barbiturates		drug allergen;
intravenous anaesthetic
estradiol 17 beta-cypionate[no description available]medium10steroid ester
testosterone enanthate[no description available]medium10heptanoate ester;
sterol ester		androgen
betamethasone[no description available]medium5011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent
podophyllotoxin[no description available]medium20furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
levocarnitine[no description available]medium30carnitineantilipemic drug;
nootropic agent;
nutraceutical;
Saccharomyces cerevisiae metabolite;
water-soluble vitamin (role)
megestrol acetate[no description available]medium4020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
steroid ester		antineoplastic agent;
appetite enhancer;
contraceptive drug;
progestin;
synthetic oral contraceptive
acetylcysteine[no description available]medium70acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
erythromycin[no description available]medium80cyclic ketone;
erythromycin
levonorgestrel[no description available]medium2017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound		contraceptive drug;
female contraceptive drug;
progestin;
synthetic oral contraceptive
estradiol valerate[no description available]medium10steroid ester
ethambutol[no description available]medium50ethanolamines;
ethylenediamine derivative		antitubercular agent;
environmental contaminant;
xenobiotic
dronabinol[no description available]medium30benzochromene;
diterpenoid;
phytocannabinoid;
polyketide		cannabinoid receptor agonist;
epitope;
hallucinogen;
metabolite;
non-narcotic analgesic
betamethasone valerate[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
primary alpha-hydroxy ketone;
steroid ester		anti-inflammatory drug
methylprednisolone hemisuccinate[no description available]medium10corticosteroid hormone;
hemisuccinate
stavudine[no description available]medium70dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
cyclacillin[no description available]medium10penicillinantibacterial drug
tranylcypromine[no description available]medium9602-phenylcyclopropan-1-amine
tranylcypromine[no description available]medium9642-phenylcyclopropan-1-amine
cladribine[no description available]medium40organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
beclomethasone[no description available]medium4011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug
estradiol enanthate[no description available]medium10steroid ester
betamethasone-17,21-dipropionate[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
propanoate ester;
steroid ester		antipsoriatic
olsalazine[no description available]medium30azobenzenes;
dicarboxylic acid		non-steroidal anti-inflammatory drug;
prodrug
zalcitabine[no description available]medium60pyrimidine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
selegiline[no description available]medium50selegiline;
terminal acetylenic compound		geroprotector
levamisole[no description available]medium406-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazoleantinematodal drug;
antirheumatic drug;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
immunological adjuvant;
immunomodulator
cephalexin[no description available]medium20beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug
isosorbide-5-mononitrate[no description available]medium10glucitol derivative;
nitrate ester		nitric oxide donor;
vasodilator agent
danazol[no description available]medium8017beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector
cephapirin[no description available]medium10cephalosporinantibacterial drug
bromocriptine[no description available]medium110indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist
metipranolol[no description available]medium10acetate ester;
aromatic ether;
propanolamine;
secondary amino compound		anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
halazepam[no description available]medium20organic molecular entity
du-21220[no description available]medium10benzyl alcohols;
polyphenol;
secondary alcohol;
secondary amino compound
cefazolin[no description available]medium30beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug
amoxicillin[no description available]medium60penicillin allergen;
penicillin		antibacterial drug
moricizine[no description available]high70carbamate ester;
morpholines;
phenothiazines		anti-arrhythmia drug
bitolterol[no description available]medium10carboxylic ester;
diester;
ethanolamines;
secondary alcohol;
secondary amino compound		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
prodrug
tobramycin[no description available]medium40amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin
etoposide[no description available]medium120beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
dobutamine[no description available]medium60catecholamine;
secondary amine		beta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
penbutolol[no description available]medium30ethanolamines
ribavirin[no description available]medium601-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
guanadrel[no description available]medium10guanidines;
spiroketal		adrenergic antagonist;
antihypertensive agent
methyldopa[no description available]medium100L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
tocainide[no description available]medium20monocarboxylic acid amideanti-arrhythmia drug;
local anaesthetic;
sodium channel blocker
sq-11725[no description available]medium50
levobunolol[no description available]medium10aromatic ether;
cyclic ketone;
propanolamine		antiglaucoma drug;
beta-adrenergic antagonist
vecuronium bromide[no description available]medium10organic bromide salt;
quaternary ammonium salt		muscle relaxant;
neuromuscular agent;
nicotinic antagonist
permethrin[no description available]medium30cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
sufentanil[no description available]medium20anilide;
ether;
piperidines;
thiophenes		anaesthesia adjuvant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
torsemide[no description available]medium30aminopyridine;
N-sulfonylurea;
secondary amino compound		antihypertensive agent;
loop diuretic
cefmetazole[no description available]medium20cephalosporinantibacterial drug
desflurane[no description available]medium10organofluorine compoundinhalation anaesthetic
idarubicin[no description available]medium30anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
cefonicid[no description available]medium10cephalosporinantibacterial drug
piperacillin[no description available]medium30penicillin allergen;
penicillin		antibacterial drug
paroxetine[no description available]high110aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines		antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor
captopril[no description available]medium100alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
cefoperazone[no description available]medium30cephalosporinantibacterial drug
lodoxamide[no description available]medium10organonitrogen compound;
organooxygen compound
atracurium[no description available]medium30diester;
quaternary ammonium ion		muscle relaxant;
nicotinic antagonist
butoconazole[no description available]medium10aryl sulfide;
conazole antifungal drug;
dichlorobenzene;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes
pergolide[no description available]medium40diamine;
methyl sulfide;
organic heterotetracyclic compound		antiparkinson drug;
dopamine agonist
cefadroxil anhydrous[no description available]medium40cephalosporinantibacterial drug
encainide[no description available]medium10benzamides;
piperidines		anti-arrhythmia drug;
sodium channel blocker
nedocromil[no description available]medium20dicarboxylic acid;
organic heterotricyclic compound		anti-allergic agent;
anti-asthmatic drug;
non-steroidal anti-inflammatory drug
cefaclor anhydrous[no description available]medium20cephalosporinantibacterial drug;
drug allergen
alfentanil[no description available]medium40monocarboxylic acid amide;
piperidines		central nervous system depressant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
peripheral nervous system drug
cefotetan[no description available]medium40
levocabastine[no description available]medium10piperidines
pravastatin[no description available]medium403-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic)		anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic
cabergoline[no description available]medium20N-acylureaantineoplastic agent;
antiparkinson drug;
dopamine agonist
quinapril[no description available]medium50dicarboxylic acid monoester;
ethyl ester;
isoquinolines;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
fosphenytoin[no description available]medium20imidazolidine-2,4-dione
finasteride[no description available]medium303-oxo steroid;
aza-steroid;
delta-lactam		androgen antagonist;
antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
esmolol[no description available]medium30aromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound
adapalene[no description available]medium10adamantanes;
monocarboxylic acid;
naphthoic acid		dermatologic drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
non-steroidal anti-inflammatory drug
sparfloxacin[no description available]medium10fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone
zileuton[no description available]medium601-benzothiophenes;
ureas		anti-asthmatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor;
leukotriene antagonist;
non-steroidal anti-inflammatory drug
cidofovir anhydrous[no description available]medium30phosphonic acids;
pyrimidone		anti-HIV agent;
antineoplastic agent;
antiviral drug;
photosensitizing agent
topotecan[no description available]medium30pyranoindolizinoquinolineantineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor
gemcitabine[no description available]high40organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic
ibutilide[no description available]medium20benzenes;
organic amino compound
remifentanil[no description available]medium20alpha-amino acid ester;
anilide;
monocarboxylic acid amide;
piperidinecarboxylate ester		intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
sedative
atorvastatin[no description available]medium30aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic)		environmental contaminant;
xenobiotic
lamivudine[no description available]medium70monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol		allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug
irinotecan[no description available]medium40carbamate ester;
delta-lactone;
N-acylpiperidine;
pyranoindolizinoquinoline;
ring assembly;
tertiary alcohol;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
prodrug
valsartan[no description available]medium70biphenylyltetrazole;
monocarboxylic acid amide;
monocarboxylic acid		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
adenosine[no description available]medium150adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
cefprozil[no description available]medium20cephalosporin;
semisynthetic derivative		antibacterial drug
methylprednisolone aceponate[no description available]medium10corticosteroid hormone
dexamethasone 17-valerate[no description available]medium1021-hydroxy steroid
dexamethasone dipropionate[no description available]medium10corticosteroid hormone
iopamidol[no description available]medium30benzenedicarboxamide;
organoiodine compound;
pentol		environmental contaminant;
radioopaque medium;
xenobiotic
dexfenfluramine[no description available]medium20fenfluramineappetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
sertraline[no description available]medium90dichlorobenzene;
secondary amino compound;
tetralins		antidepressant;
serotonin uptake inhibitor
erythromycin propionate[no description available]medium10erythromycin derivative
dexrazoxane[no description available]medium20razoxaneantineoplastic agent;
cardiovascular drug;
chelator;
immunosuppressive agent
antebate[no description available]medium10corticosteroid hormone
atovaquone[no description available]medium40hydroxy-1,2-naphthoquinone
flunisolide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
primary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug;
immunosuppressive agent
nicotine[no description available]medium1403-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
moexipril[no description available]medium30peptide
methotrexate[no description available]medium80dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
docetaxel[no description available]medium20hydrate;
secondary alpha-hydroxy ketone		antineoplastic agent
levofloxacin[no description available]medium509-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
ropivacaine[no description available]medium20piperidinecarboxamide;
ropivacaine		local anaesthetic
estradiol 3-benzoate[no description available]medium1017beta-hydroxy steroid;
benzoate ester		estrogen receptor agonist;
xenoestrogen
estramustine[no description available]medium3017beta-hydroxy steroid;
carbamate ester;
organochlorine compound		alkylating agent;
antineoplastic agent;
radiation protective agent
ritonavir[no description available]medium801,3-thiazoles;
carbamate ester;
carboxamide;
L-valine derivative;
ureas		antiviral drug;
environmental contaminant;
HIV protease inhibitor;
xenobiotic
pentostatin[no description available]medium20coformycinsantimetabolite;
antineoplastic agent;
Aspergillus metabolite;
bacterial metabolite;
EC 3.5.4.4 (adenosine deaminase) inhibitor
meropenem[no description available]medium20alpha,beta-unsaturated monocarboxylic acid;
carbapenemcarboxylic acid;
organic sulfide;
pyrrolidinecarboxamide		antibacterial agent;
antibacterial drug;
drug allergen
cefoxitin[no description available]medium40beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug
saquinavir[no description available]medium60L-asparagine derivative;
quinolines		antiviral drug;
HIV protease inhibitor
netilmicin[no description available]medium10
metyrosine[no description available]medium30L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		antihypertensive agent;
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor
rocuronium bromide[no description available]medium10organic bromide salt;
quaternary ammonium salt		muscle relaxant;
neuromuscular agent
terconazole[no description available]medium101-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine
bacampicillin[no description available]medium10penicillanic acid esterprodrug
erythromycin ethylsuccinate[no description available]medium10cyclic ketone;
erythromycin derivative;
ethyl ester;
succinate ester
amcinonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
corticosteroid;
fluorinated steroid;
spiroketal		anti-inflammatory drug
betamethasone acetate[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
fluorinated steroid;
steroid ester;
tertiary alpha-hydroxy ketone
acarbose[no description available]medium20amino cyclitol;
glycoside
mupirocin[no description available]medium10alpha,beta-unsaturated carboxylic ester;
epoxide;
monocarboxylic acid;
oxanes;
secondary alcohol;
triol		antibacterial drug;
bacterial metabolite;
protein synthesis inhibitor
fosfomycin[no description available]medium20epoxide;
phosphonic acids		antimicrobial agent;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor
zithromax[no description available]medium60macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic
teniposide[no description available]medium30aromatic ether;
beta-D-glucoside;
cyclic acetal;
furonaphthodioxole;
gamma-lactone;
monosaccharide derivative;
phenols;
thiophenes		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
cefamandole[no description available]medium10cephalosporin;
semisynthetic derivative		antibacterial drug
dactinomycin[no description available]medium150actinomycinmutagen
melphalan[no description available]medium50L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
sch 22219[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
glucocorticoid;
propanoate ester;
steroid ester		anti-inflammatory drug
mezlocillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
cholinophyllin[no description available]medium10
fludarabine[no description available]medium10purine nucleoside
propylthiouracil[no description available]medium40pyrimidinethioneantidote to paracetamol poisoning;
antimetabolite;
antioxidant;
antithyroid drug;
carcinogenic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
hormone antagonist
ipratropium bromide anhydrous[no description available]medium20
etomidate[no description available]medium40ethyl ester;
imidazoles		intravenous anaesthetic;
sedative
mercaptopurine[no description available]medium60aryl thiol;
purines;
thiocarbonyl compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent
benztropine[no description available]medium200diarylmethane
benztropine[no description available]medium202diarylmethane
thioguanine anhydrous[no description available]medium602-aminopurinesanticoronaviral agent;
antimetabolite;
antineoplastic agent
succimer[no description available]medium20dicarboxylic acid;
dithiol;
sulfur-containing carboxylic acid		chelator
streptozocin[no description available]medium50
ethionamide[no description available]medium50pyridines;
thiocarboxamide		antilipemic drug;
antitubercular agent;
fatty acid synthesis inhibitor;
leprostatic drug;
prodrug
dezocine[no description available]medium10phenols;
primary amino compound		opioid analgesic
dapiprazole[no description available]medium10N-alkylpiperazine;
N-arylpiperazine;
pyridines		alpha-adrenergic antagonist;
antipsychotic agent;
miotic;
ophthalmology drug
flosequinan[no description available]medium10quinolines
calcitriol[no description available]medium120D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
alprostadil[no description available]medium80prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
alprostadil[no description available]medium81prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
amphotericin b[no description available]medium120antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
pulmicort[no description available]medium4011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen
olopatadine[no description available]medium10
bw b1090u[no description available]medium10isoquinolines
7432 s[no description available]medium20cephalosporin;
dicarboxylic acid		antibacterial drug
etretinate[no description available]medium10enoate ester;
ethyl ester;
retinoid		keratolytic drug
misoprostol[no description available]medium20
epoprostenol[no description available]medium20prostaglandins Imouse metabolite
betamethasone benzoate[no description available]medium1021-hydroxy steroid
dorzolamide[no description available]medium20sulfonamide;
thiophenes		antiglaucoma drug;
antihypertensive agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
ly 163892[no description available]medium50carbacephem;
zwitterion		antibacterial drug;
antimicrobial agent
topiramate[no description available]medium50cyclic ketal;
ketohexose derivative;
sulfamate ester		anticonvulsant;
sodium channel blocker
calcipotriene[no description available]medium10cyclopropanes;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
triol		antipsoriatic;
drug allergen
clobetasol[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid;
tertiary alpha-hydroxy ketone		anti-inflammatory drug;
SMO receptor agonist
fluticasone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
fluorinated steroid;
thioester		anti-allergic agent;
anti-asthmatic drug
halobetasol[no description available]medium10corticosteroid hormone
latanoprost[no description available]medium10isopropyl ester;
prostaglandins Falpha;
triol		antiglaucoma drug;
antihypertensive agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
prodrug
rimexolone[no description available]medium1020-oxo steroid
vinorelbine[no description available]medium40acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
ring assembly;
vinca alkaloid		antineoplastic agent;
photosensitizing agent
fluvoxamine[no description available]medium50(trifluoromethyl)benzenes;
5-methoxyvalerophenone O-(2-aminoethyl)oxime		antidepressant;
anxiolytic drug;
serotonin uptake inhibitor
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]medium50dihydroxy monocarboxylic acid;
indoles;
organofluorine compound
oxiconazole[no description available]medium10conazole antifungal drug;
dichlorobenzene;
imidazole antifungal drug;
imidazoles;
oxime O-ether		antiinfective agent
butorphanol[no description available]medium20morphinane alkaloidantitussive;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic
cefixime[no description available]medium30cephalosporinantibacterial drug;
drug allergen
lisinopril[no description available]medium50dipeptideEC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
benazepril[no description available]medium40benzazepine;
dicarboxylic acid monoester;
ethyl ester;
lactam		EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
ramipril[no description available]medium20azabicycloalkane;
cyclopentapyrrole;
dicarboxylic acid monoester;
dipeptide;
ethyl ester		bradykinin receptor B2 agonist;
cardioprotective agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
matrix metalloproteinase inhibitor;
prodrug
indinavir sulfate[no description available]medium60dicarboxylic acid diamide;
N-(2-hydroxyethyl)piperazine;
piperazinecarboxamide		HIV protease inhibitor
enalapril[no description available]medium40dicarboxylic acid monoester;
dipeptide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
geroprotector;
prodrug
cefuroxime[no description available]medium203-(carbamoyloxymethyl)cephalosporin;
furans;
oxime O-ether		drug allergen
ceftriaxone[no description available]medium201,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor
cefepime[no description available]medium20cephalosporin;
oxime O-ether		antibacterial drug
ceftazidime[no description available]medium40cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
trandolapril[no description available]medium20dicarboxylic acid monoester;
dipeptide;
ethyl ester;
organic heterobicyclic compound;
secondary amino compound;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
guanabenz[no description available]medium20dichlorobenzene
famotidine[no description available]medium501,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
cefotaxime[no description available]medium201,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen
aztreonam[no description available]medium40beta-lactam antibiotic allergen;
monobactam		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
cci 15641[no description available]medium10cephalosporin
cefpodoxime[no description available]medium20carboxylic acid;
cephalosporin		antibacterial drug
dirithromycin[no description available]medium10macrolide antibioticprodrug
cefpodoxime proxetil[no description available]medium10carboxylic acid;
carboxylic ester;
cephalosporin		antibacterial drug;
prodrug
ceftizoxime[no description available]medium20cephalosporinantibacterial drug
dantrolene[no description available]medium40
fosinopril[no description available]medium20
nystatin a1[no description available]medium40nystatins
mesna[no description available]medium20organosulfonic acid
cefamandole nafate[no description available]medium10organic sodium saltantibacterial drug;
prodrug
minocycline[no description available]medium70
piroxicam[no description available]medium70benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
meclocycline[no description available]medium10
acyclovir[no description available]medium502-aminopurines;
oxopurine		antimetabolite;
antiviral drug
didanosine[no description available]medium60purine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor;
geroprotector;
HIV-1 reverse transcriptase inhibitor
ganciclovir[no description available]medium402-aminopurines;
oxopurine		antiinfective agent;
antiviral drug
valacyclovir[no description available]medium30L-valyl esterantiviral drug
penciclovir[no description available]medium202-aminopurines;
propane-1,3-diols		antiviral drug
rifabutin[no description available]medium50
2-cresol[no description available]medium10cresolhuman xenobiotic metabolite
phenylacetic acid[no description available]medium10benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
antipyrine[no description available]medium20pyrazoloneantipyretic;
cyclooxygenase 3 inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
4-chlorophenol[no description available]medium10monochlorophenol
4-phenylbutyric acid[no description available]medium30monocarboxylic acidantineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor;
prodrug
resorcinol[no description available]medium10benzenediol;
phenolic donor;
resorcinols		erythropoietin inhibitor;
sensitiser
sulfabenzamide[no description available]medium30benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug
sulfacetamide[no description available]medium20N-sulfonylcarboxamide;
substituted aniline		antibacterial drug;
antiinfective agent;
antimicrobial agent;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfanilamide[no description available]medium30substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
tolbutamide[no description available]medium110N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
2,4,6-trichlorophenol[no description available]medium10trichlorophenolcarcinogenic agent
1-chloro-2-nitrobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes
n,n-diethylaniline[no description available]medium10
methyl nicotinate[no description available]medium10aromatic carboxylic acid;
pyridines
nicotinic acid benzyl ester[no description available]medium10benzyl estervasodilator agent
3,4-dimethylphenol[no description available]medium10phenols
4-bromophenol[no description available]medium30bromophenolhuman urinary metabolite;
human xenobiotic metabolite;
marine metabolite;
mouse metabolite;
persistent organic pollutant;
rat metabolite
isoquinoline[no description available]medium10azaarene;
isoquinolines;
mancude organic heterobicyclic parent;
ortho-fused heteroarene
sulfanilylurea[no description available]medium30benzenes;
sulfonamide
5-phenylvaleric acid[no description available]medium10benzenes;
monocarboxylic acid
triamcinolone[no description available]medium2011beta-hydroxy steroid;
16alpha-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
4-n-butylaminobenzoic acid[no description available]medium10aromatic amino acid
2-amino-4-nitrophenol[no description available]medium104-nitrophenols
2-nitro-4-phenylenediamine[no description available]medium10C-nitro compound;
primary amino compound
diphenyleneiodium chloride[no description available]medium20organic chloride saltEC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
G-protein-coupled receptor agonist
genistein[no description available]medium407-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
mepazine[no description available]medium110phenothiazines
chlorpromazine hydrochloride[no description available]high10hydrochloride;
phenothiazines		anticoronaviral agent;
phenothiazine antipsychotic drug
eskazine[no description available]medium10
acetone[no description available]medium20ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
carbon monoxide[no description available]medium20carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
nitrous oxide[no description available]medium50gas molecular entity;
nitrogen oxide		analgesic;
bacterial metabolite;
food packaging gas;
food propellant;
general anaesthetic;
greenhouse gas;
inhalation anaesthetic;
NMDA receptor antagonist;
raising agent;
refrigerant;
vasodilator agent
clotiazepam[no description available]medium10organic molecular entity
ethenzamide[no description available]medium10organic molecular entity
hexobarbital[no description available]medium40barbiturates
methoxyflurane[no description available]medium20ether;
organochlorine compound;
organofluorine compound		hepatotoxic agent;
inhalation anaesthetic;
nephrotoxic agent;
non-narcotic analgesic
methylphenidate[no description available]medium110beta-amino acid ester;
methyl ester;
piperidines
methylphenidate[no description available]medium111beta-amino acid ester;
methyl ester;
piperidines
nalidixic acid[no description available]medium501,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
nitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative
oxprenolol[no description available]medium30aromatic ether
tegafur[no description available]medium10organohalogen compound;
pyrimidines
trihexyphenidyl[no description available]medium210amine
chloroform[no description available]medium50chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
ethane[no description available]medium10alkane;
gas molecular entity		plant metabolite;
refrigerant
ethylene[no description available]medium10alkene;
gas molecular entity		plant hormone;
refrigerant
acetylene[no description available]medium10alkyne;
gas molecular entity;
terminal acetylenic compound
methylene chloride[no description available]medium10chloromethanes;
volatile organic compound		carcinogenic agent;
polar aprotic solvent;
refrigerant
cyclopropane[no description available]medium170cycloalkane;
cyclopropanes		inhalation anaesthetic
ethylene oxide[no description available]medium10gas molecular entity;
oxacycle;
saturated organic heteromonocyclic parent		allergen;
mouse metabolite;
mutagen
1,1,1-trifluoro-2-chloroethane[no description available]medium10organofluorine compound
butobarbital[no description available]medium10barbiturates
isobutyl alcohol[no description available]medium10alkyl alcohol;
primary alcohol		Saccharomyces cerevisiae metabolite
acrylic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acidmetabolite
penicillin v[no description available]medium20penicillin allergen;
penicillin
2-xylene[no description available]medium10xylene
3-methylpentane[no description available]medium10alkane;
volatile organic compound		allelochemical;
human metabolite;
non-polar solvent
methylcyclopentane[no description available]medium10cycloalkane;
volatile organic compound		human metabolite;
plant metabolite
4-chloro-alpha,alpha,alpha-trifluorotoluene[no description available]medium10
1,3-butadiene[no description available]medium10butadienecarcinogenic agent;
mutagen
2-methylpentane[no description available]medium10alkane
propylene[no description available]medium10alkene;
gas molecular entity		refrigerant;
xenobiotic
n-heptane[no description available]medium10alkane;
volatile organic compound		non-polar solvent;
plant metabolite
glycyrrhetinic acid[no description available]medium10cyclic terpene ketone;
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		immunomodulator;
plant metabolite
sulfur hexafluoride[no description available]medium10sulfur coordination entitygreenhouse gas;
NMR chemical shift reference compound;
ultrasound contrast agent
toliprolol[no description available]medium10aromatic ether
dicloxacillin[no description available]medium30dichlorobenzene;
penicillin		antibacterial drug
helium[no description available]medium10monoatomic helium;
noble gas atom;
s-block element atom		food packaging gas
chloroprene[no description available]medium10chloroolefin
tetrachloroethylene[no description available]medium10chlorocarbon;
chloroethenes		nephrotoxic agent
miloxacin[no description available]medium10quinolines
inaperisone[no description available]medium10aromatic ketone
4-phenylbenzoic acid[no description available]medium10
cdri 81-470[no description available]medium10
yh 1885[no description available]medium10
cotinine[no description available]medium10N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite
digoxin[no description available]medium80cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
thiopental[no description available]medium90barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
sch 442416[no description available]medium10triazolopyrimidines
mobiflex[no description available]medium20heteroaryl hydroxy compound;
monocarboxylic acid amide;
pyridines;
thienothiazine		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
1-(10h-phenothiazin-2-yl)ethanone[no description available]medium10phenothiazines
4-phenyl-3-furoxancarbonitrile[no description available]medium101,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
1-(4-methanesulfonamidophenoxy)-3-(n-methyl-3,4-dichlorophenylethylamino)-2-propanol[no description available]medium10sulfonamide
2,2-bis(4-glycidyloxyphenyl)propane[no description available]medium10diarylmethane
bay-k-8644[no description available]medium200(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
bisindolylmaleimide i[no description available]medium10
cypermethrin[no description available]medium10aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound		agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide
fluspirilene[no description available]medium50diarylmethane
fpl 64176[no description available]medium10carboxylic ester;
pyrroles		calcium channel agonist
n-(2-aminoethyl)-5-isoquinolinesulfonamide[no description available]medium30
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one[no description available]medium60chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
ml 9[no description available]medium10naphthalenes;
sulfonic acid derivative
ro 31-8220[no description available]medium10imidothiocarbamic ester;
indoles;
maleimides		EC 2.7.11.13 (protein kinase C) inhibitor
sb 202190[no description available]medium10imidazoles;
organofluorine compound;
phenols;
pyridines		apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
dpi 201-106[no description available]medium30diarylmethane
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate[no description available]medium490trihydroxybenzoic acid
cantharidin[no description available]medium10cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide
indirubin[no description available]medium10
nigericin[no description available]medium40polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore
castanospermine[no description available]medium10indolizidine alkaloidanti-HIV-1 agent;
anti-inflammatory agent;
EC 3.2.1.* (glycosidase) inhibitor;
metabolite
niguldipine[no description available]medium10diarylmethane
aloxistatin[no description available]medium20epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide		anticoronaviral agent;
cathepsin B inhibitor
chelerythrine chloride[no description available]medium10
calpeptin[no description available]medium20amino acid amide
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole[no description available]medium10ether;
imidazoles;
monomethoxybenzene		TRP channel blocker
paxilline[no description available]medium20diterpene alkaloid;
enone;
organic heterohexacyclic compound;
terpenoid indole alkaloid;
tertiary alcohol		anticonvulsant;
Aspergillus metabolite;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor;
genotoxin;
geroprotector;
mycotoxin;
Penicillium metabolite;
potassium channel blocker
24-hydroxycholesterol[no description available]medium1024-hydroxycholesterolbiomarker;
human blood serum metabolite;
mouse metabolite
ilomastat[no description available]medium20hydroxamic acid;
L-tryptophan derivative;
N-acyl-amino acid		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
EC 3.4.24.24 (gelatinase A) inhibitor;
neuroprotective agent
tanshinone ii a[no description available]medium20abietane diterpenoid
monensin[no description available]medium110cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
cyclopamine[no description available]medium10piperidinesglioma-associated oncogene inhibitor
acetylleucyl-leucyl-norleucinal[no description available]medium20aldehyde;
tripeptide		cysteine protease inhibitor
trichostatin a[no description available]medium10antibiotic antifungal agent;
hydroxamic acid;
trichostatin		bacterial metabolite;
EC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector
thapsigargin[no description available]medium220butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
aphidicolin[no description available]medium10tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite
gw9662[no description available]medium10benzamides
caffeic acid phenethyl ester[no description available]medium10alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent
sirolimus[no description available]medium60antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
geldanamycin[no description available]medium101,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound		antimicrobial agent;
antineoplastic agent;
antiviral agent;
cysteine protease inhibitor;
Hsp90 inhibitor
cytochalasin b[no description available]medium380cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor
cytochalasin d[no description available]medium20
latrunculin b[no description available]medium10cyclic hemiketal;
macrolide;
oxabicycloalkane;
thiazolidinone		actin polymerisation inhibitor;
metabolite;
toxin
bafilomycin a1[no description available]medium30cyclic hemiketal;
macrolide antibiotic;
oxanes		apoptosis inducer;
autophagy inhibitor;
bacterial metabolite;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
ferroptosis inhibitor;
fungicide;
potassium ionophore;
toxin
tanespimycin[no description available]medium101,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
Hsp90 inhibitor
ca 074 methyl ester[no description available]medium10
grayanotoxin iii[no description available]medium10
alpha-cyclopiazonic acid[no description available]medium20alpha-cyclopiazonic acids
antazoline[no description available]medium20aromatic amine;
imidazolines;
tertiary amino compound		cholinergic antagonist;
H1-receptor antagonist;
xenobiotic
benfluorex[no description available]medium10benzoate ester
bromhexine[no description available]medium30organobromine compound;
substituted aniline;
tertiary amino compound		mucolytic
bromopride[no description available]medium10benzamides
bromperidol[no description available]medium20aromatic ketone
carbetapentane[no description available]medium10benzenes
chloroquine[no description available]medium150aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
citalopram[no description available]high602-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound
clebopride[no description available]medium10piperidines
clomiphene[no description available]medium50tertiary amineestrogen antagonist;
estrogen receptor modulator
cloperastine[no description available]medium10diarylmethane
diphenylpyraline[no description available]medium20piperidines;
tertiary amine		cholinergic antagonist;
H1-receptor antagonist
domperidone[no description available]high50benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
donepezil[no description available]medium50aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
cycloadiphenine[no description available]medium10benzenes
fendiline[no description available]medium100diarylmethane
fipexide[no description available]medium50benzodioxoles
flavoxate[no description available]medium30carboxylic ester;
flavones;
piperidines;
tertiary amino compound		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
alverine[no description available]medium10tertiary amineantispasmodic drug
lofepramine[no description available]medium30aromatic ketone;
dibenzoazepine;
monochlorobenzenes;
tertiary amino compound		antidepressant
mebeverine[no description available]medium10methoxybenzoic acid
mecamylamine[no description available]medium30primary aliphatic amine
memantine[no description available]medium50adamantanes;
primary aliphatic amine		antidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
norfluoxetine[no description available]medium10(trifluoromethyl)benzenes
orphenadrine[no description available]medium80ether;
tertiary amino compound		antidyskinesia agent;
antiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
oxidopamine[no description available]medium20benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
oxybutynin[no description available]medium40acetylenic compound;
carboxylic ester;
racemate;
tertiary alcohol;
tertiary amino compound		antispasmodic drug;
calcium channel blocker;
local anaesthetic;
muscarinic antagonist;
muscle relaxant;
parasympatholytic
oxymetazoline[no description available]medium10carboxamidine;
imidazolines;
phenols		alpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
oxyphencyclimine[no description available]medium10monocarboxylic acid
perhexiline[no description available]medium100piperidinescardiovascular drug
pimethixene[no description available]medium10thioxanthenes
pipamperone[no description available]high10aromatic ketone;
bipiperidines;
monocarboxylic acid amide;
organofluorine compound;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
pridinol[no description available]medium10piperidines;
tertiary alcohol		antiparkinson drug;
muscle relaxant
procyclidine[no description available]medium90pyrrolidines;
tertiary alcohol		antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist
procyclidine[no description available]medium91pyrrolidines;
tertiary alcohol		antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist
sibutramine[no description available]medium20organochlorine compound;
tertiary amino compound		anti-obesity agent;
serotonin uptake inhibitor
2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol[no description available]medium30alkylbenzene
sulpiride[no description available]high151benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
sulpiride[no description available]high150benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
tofisopam[no description available]medium10organic molecular entity
xylometazoline[no description available]medium20alkylbenzene
camylofine[no description available]medium10alpha-amino acid ester
cycloheximide[no description available]medium220antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
azacitidine[no description available]medium50N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
penfluridol[no description available]medium80diarylmethane
penfluridol[no description available]medium82diarylmethane
flupirtine[no description available]medium10aminopyridine
mifepristone[no description available]medium403-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive
mibefradil[no description available]medium30tetralinsT-type calcium channel blocker
esreboxetine[no description available]medium10aromatic ether
lercanidipine[no description available]medium10diarylmethane
cloricromen[no description available]medium10coumarins
demecolcine[no description available]medium20alkaloid;
secondary amino compound		antineoplastic agent;
microtubule-destabilising agent
noscapine[no description available]medium10aromatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound		antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite
vinpocetine[no description available]medium20alkaloidgeroprotector
harmine[no description available]medium30harmala alkaloidanti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
metabolite
triprolidine[no description available]medium40N-alkylpyrrolidine;
olefinic compound;
pyridines		H1-receptor antagonist
dextromethorphan[no description available]medium406-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthreneantitussive;
environmental contaminant;
neurotoxin;
NMDA receptor antagonist;
oneirogen;
prodrug;
xenobiotic
triclosan[no description available]medium10aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic
gentian violet[no description available]medium10organic chloride saltanthelminthic drug;
antibacterial agent;
antifungal agent;
antiseptic drug;
histological dye
ethidium bromide[no description available]medium10organic bromide saltgeroprotector;
intercalator;
trypanocidal drug
acridine orange[no description available]medium20aminoacridines;
aromatic amine;
tertiary amino compound		fluorochrome;
histological dye
miconazole[no description available]medium80dichlorobenzene;
ether;
imidazoles
4-nitroquinoline-1-oxide[no description available]medium10C-nitro compound;
quinoline N-oxide		carcinogenic agent
voriconazole[no description available]medium30conazole antifungal drug;
difluorobenzene;
pyrimidines;
tertiary alcohol;
triazole antifungal drug		P450 inhibitor
latrunculin a[no description available]medium20cyclic hemiketal;
macrolide;
oxabicycloalkane;
thiazolidinone		actin polymerisation inhibitor;
metabolite;
toxin
tacrolimus[no description available]medium110macrolide lactambacterial metabolite;
immunosuppressive agent
cerulenin[no description available]medium20epoxide;
monocarboxylic acid amide		antifungal agent;
antiinfective agent;
antilipemic drug;
antimetabolite;
antimicrobial agent;
fatty acid synthesis inhibitor
ly 295337[no description available]medium10
rhodamine 123[no description available]medium10organic chloride salt;
xanthene dye		fluorochrome
thiethylperazine[no description available]high90N-methylpiperazine;
phenothiazines		antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
amineptin[no description available]medium40amino acid;
carbocyclic fatty acid;
carbotricyclic compound;
secondary amino compound		antidepressant;
dopamine uptake inhibitor
diethazine[no description available]medium20phenothiazines
methotrimeprazine[no description available]high350phenothiazines;
tertiary amine		anticoronaviral agent;
cholinergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
non-narcotic analgesic;
phenothiazine antipsychotic drug;
serotonergic antagonist
1,10-phenanthroline[no description available]medium10phenanthrolineEC 2.7.1.1 (hexokinase) inhibitor;
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
clotrimazole[no description available]medium90conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
diphenyleneiodonium[no description available]medium30organic cation
niclosamide[no description available]medium20benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
vancomycin[no description available]medium50glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
streptomycin[no description available]medium80antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
methoctramine[no description available]medium10hydrochloridemuscarinic antagonist
selenomethylselenocysteine[no description available]medium10amino acid zwitterion;
L-selenocysteine derivative;
non-proteinogenic L-alpha-amino acid;
Se-methylselenocysteine		antineoplastic agent
calmidazolium[no description available]medium20organic chloride saltapoptosis inducer;
calmodulin antagonist
ly 367265[no description available]medium10dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor
bay 11-7085[no description available]medium10benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor
calcimycin[no description available]medium2020benzoxazole
demeclocycline[no description available]medium20
aminooxyacetic acid[no description available]medium20amino acid;
hydroxylamines;
monocarboxylic acid		anticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
nootropic agent
acetazolamide[no description available]medium80monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
aprindine[no description available]medium10indanes
bretylium[no description available]medium20quaternary ammonium ionadrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent
chlorpropamide[no description available]medium70monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
chlorthalidone[no description available]medium20isoindoles;
monochlorobenzenes;
sulfonamide
clenbuterol[no description available]medium10amino alcohol;
dichlorobenzene;
ethanolamines;
primary arylamine;
secondary amino compound;
substituted aniline		beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
clioquinol[no description available]medium10monohydroxyquinoline;
organochlorine compound;
organoiodine compound		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antiprotozoal drug;
chelator;
copper chelator
debrisoquin[no description available]medium20carboxamidine;
isoquinolines		adrenergic agent;
antihypertensive agent;
human metabolite;
sympatholytic agent
3,4-dihydroxybenzohydroxamic acid[no description available]medium10benzoic acids
dimercaprol[no description available]medium40dithiol;
primary alcohol		chelator
ethosuximide[no description available]medium60dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker
ethyl loflazepate[no description available]medium10organic molecular entity
glutethimide[no description available]medium50piperidines
guanethidine[no description available]medium60azocanes;
guanidines		adrenergic antagonist;
antihypertensive agent;
sympatholytic agent
incadronate[no description available]medium101,1-bis(phosphonic acid)
nsc 664704[no description available]medium10indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector
ketamine[no description available]medium70cyclohexanones;
monochlorobenzenes;
secondary amino compound		analgesic;
environmental contaminant;
intravenous anaesthetic;
neurotoxin;
NMDA receptor antagonist;
xenobiotic
ketanserin[no description available]medium10aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
lomustine[no description available]medium20N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
mazindol[no description available]medium10organic molecular entity
mechlorethamine[no description available]medium20nitrogen mustard;
organochlorine compound		alkylating agent
mephenytoin[no description available]medium30imidazolidine-2,4-dioneanticonvulsant
methoxyamine[no description available]medium10organooxygen compound
nitroglycerin[no description available]medium40nitroglycerolexplosive;
muscle relaxant;
nitric oxide donor;
prodrug;
tocolytic agent;
vasodilator agent;
xenobiotic
nomifensine[no description available]medium60isoquinolinesdopamine uptake inhibitor
olomoucine[no description available]medium102,6-diaminopurines;
ethanolamines		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
oxatomide[no description available]medium20benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist
pantoprazole[no description available]medium20aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic
phenindione[no description available]medium10aromatic ketone;
beta-diketone		anticoagulant
phentermine[no description available]medium40primary amineadrenergic agent;
appetite depressant;
central nervous system drug;
central nervous system stimulant;
dopaminergic agent;
sympathomimetic agent
primaquine[no description available]medium50aminoquinoline;
aromatic ether;
N-substituted diamine		antimalarial
pyrimethamine[no description available]medium50aminopyrimidine;
monochlorobenzenes		antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
rabeprazole[no description available]medium20benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
risedronic acid[no description available]medium30pyridines
sulforaphane[no description available]medium10isothiocyanate;
sulfoxide		antineoplastic agent;
antioxidant;
EC 3.5.1.98 (histone deacetylase) inhibitor;
plant metabolite
terbutaline[no description available]medium50phenylethanolamines;
resorcinols		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
sympathomimetic agent;
tocolytic agent
triamterene[no description available]medium30pteridinesdiuretic;
sodium channel blocker
trimethoprim[no description available]medium70aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
zopiclone[no description available]medium10monochloropyridine;
pyrrolopyrazine		central nervous system depressant;
sedative
paramethasone[no description available]medium10fluorinated steroid
cetrimonium bromide[no description available]medium10organic bromide salt;
quaternary ammonium salt		detergent;
surfactant
levodopa[no description available]medium130amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
fluocinolone acetonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
organic heteropentacyclic compound;
primary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
sulfobromophthalein sodium[no description available]medium10organic sodium saltdye
pseudoephedrine[no description available]medium20phenylethanolamines;
secondary alcohol;
secondary amino compound		anti-asthmatic drug;
bronchodilator agent;
central nervous system drug;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
phenformin[no description available]medium20biguanidesantineoplastic agent;
geroprotector;
hypoglycemic agent
sterogenol[no description available]medium10bromide salt;
pyridinium salt		antiseptic drug;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
surfactant
cycloguanil[no description available]medium20triazinesantifolate;
antiinfective agent;
antimalarial;
antiparasitic agent;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
benzohydroxamic acid[no description available]medium10
medroxyprogesterone[no description available]medium2017alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
tertiary alpha-hydroxy ketone		contraceptive drug;
progestin;
synthetic oral contraceptive
sulfadoxine[no description available]medium20pyrimidines;
sulfonamide		antibacterial drug;
antimalarial
pyrodifenium bromide[no description available]medium10organic molecular entity
amopyroquine[no description available]medium10
xipamide[no description available]medium10benzamides
benzonidazole[no description available]medium10C-nitro compound;
imidazoles;
monocarboxylic acid amide		antiprotozoal drug
dexchlorpheniramine[no description available]medium20chlorphenamine
halofantrine[no description available]medium10phenanthrenes
hydroxymaprotilin[no description available]medium10
pinazepam[no description available]medium10benzodiazepine
butibufen[no description available]medium10monoterpenoid
piritrexim[no description available]medium10
bambuterol[no description available]medium30carbamate ester;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent;
tocolytic agent
salmeterol xinafoate[no description available]medium10naphthoic acid
ibandronic acid[no description available]medium20
trovafloxacin[no description available]medium50
ursolic acid[no description available]medium10hydroxy monocarboxylic acid;
pentacyclic triterpenoid		geroprotector;
plant metabolite
propamidine[no description available]medium10aromatic ether;
guanidines;
polyether		antimicrobial agent;
antiseptic drug
sinefungin[no description available]medium10adenosines;
non-proteinogenic alpha-amino acid		antifungal agent;
antimicrobial agent
droxicam[no description available]medium30organic heterotricyclic compound;
pyridines		cyclooxygenase 1 inhibitor;
hepatotoxic agent;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
platelet aggregation inhibitor;
prodrug
etofibrate[no description available]medium10monocarboxylic acid
synthalin a[no description available]medium10guanidineshepatotoxic agent;
hypoglycemic agent;
nephrotoxin
ibopamine[no description available]medium10benzoate ester;
phenols
zoledronic acid[no description available]medium301,1-bis(phosphonic acid);
imidazoles		bone density conservation agent
pirlindole[no description available]medium10carbazoles
artemether[no description available]medium20artemisinin derivative;
cyclic acetal;
organic peroxide;
semisynthetic derivative;
sesquiterpenoid		antimalarial
6-amino-1-hydroxyhexane-1,1-diphosphonate[no description available]medium101,1-bis(phosphonic acid)
rexigen[no description available]medium10
aceclofenac[no description available]medium20amino acid;
carboxylic ester;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
clociguanil[no description available]medium10
tebuquine[no description available]medium10
cryptolepine[no description available]medium10indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		anti-inflammatory agent;
antimalarial;
antineoplastic agent;
cysteine protease inhibitor;
plant metabolite
cinchonine[no description available]medium10(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite
n-hexadecyl-n,n-dimethyl-3-ammonio-1-propanesulfonate[no description available]medium10
desethylchloroquine[no description available]medium10aminoquinoline
wr 159412[no description available]medium10
cinchonidine[no description available]medium10(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite
benzyloxyamine[no description available]medium10
pyronaridine[no description available]medium20aminoquinoline
tafenoquine[no description available]medium10(trifluoromethyl)benzenes;
aminoquinoline;
aromatic ether;
primary amino compound;
secondary amino compound
desethylamodiaquine[no description available]medium10
n,n-dideethylchloroquine[no description available]medium10
3,6-diamino-9-(4-(methylsulfonyl)aminophenyl)aminoacridine[no description available]medium10
ne 58051[no description available]medium10
wr 242511[no description available]medium10
cyc 202[no description available]medium102,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
deflazacort[no description available]medium10corticosteroid hormone
olpadronic acid[no description available]medium10
lupeol[no description available]medium10pentacyclic triterpenoid;
secondary alcohol		anti-inflammatory drug;
plant metabolite
neocryptolepine[no description available]medium10
1-hydroxypentane-1,1-bisphosphonate[no description available]medium10
cimadronate[no description available]medium10
1,1-hydroxyoctanodiphosphonate[no description available]medium10
oxytocin[no description available]medium60heterodetic cyclic peptide;
peptide hormone		oxytocic;
vasodilator agent
digitoxin[no description available]medium30cardenolide glycosideEC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
canaline[no description available]medium10amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		antimetabolite;
antineoplastic agent;
phytogenic insecticide;
plant metabolite
purvalanol a[no description available]medium10purvalanol
Tetrahydropiperine[no description available]medium10benzodioxoles
carbenoxolone[no description available]medium10
piperine[no description available]medium10benzodioxoles;
N-acylpiperidine;
piperidine alkaloid;
tertiary carboxamide		food component;
human blood serum metabolite;
NF-kappaB inhibitor;
plant metabolite
ilepcimide[no description available]medium10benzodioxoles
leuprolide[no description available]medium10oligopeptideanti-estrogen;
antineoplastic agent;
gonadotropin releasing hormone agonist
octotropine methylbromide[no description available]medium20
artemotil[no description available]medium10artemisinin derivative
gestodene[no description available]medium10steroidestrogen
glucametacin[no description available]medium10
alsterpaullone[no description available]medium10C-nitro compound;
caprolactams;
organic heterotetracyclic compound		anti-HIV-1 agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor
usambarensine[no description available]medium10harmala alkaloid
cynarine[no description available]medium10alkyl caffeate ester;
quinic acid		plant metabolite
dihydrocodeine[no description available]medium10morphinane alkaloid
lacidipine[no description available]medium10cinnamate ester;
tert-butyl ester
licochalcone a[no description available]medium10chalcones
stilbamidine[no description available]medium10
piperic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid;
benzodioxoles		plant metabolite
proguanil[no description available]medium40biguanides;
monochlorobenzenes		antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
nifurtimox[no description available]medium10nitrofuran antibiotic
butylscopolammonium bromide[no description available]medium10
roxithromycin[no description available]medium10roxithromycinenvironmental contaminant;
xenobiotic
artesunate[no description available]medium20artemisinin derivative;
cyclic acetal;
dicarboxylic acid monoester;
hemisuccinate;
semisynthetic derivative;
sesquiterpenoid		antimalarial;
antineoplastic agent;
ferroptosis inducer
chlorproguanil[no description available]medium10dichlorobenzene
n1-phenyl-3,5-dinitro-n4,n4-di-n-propylsulfanilamide[no description available]medium10
artenimol[no description available]medium10
4-phenoxyphenoxyethyl thiocyanate[no description available]medium10
diflucortolone[no description available]medium1021-hydroxy steroid
deoxoartemisinin[no description available]medium10
amodiaquine hydrochloride[no description available]medium10
valproate sodium[no description available]medium10organic sodium saltgeroprotector
butyrolactone i[no description available]medium10butenolide
ascorbic acid[no description available]medium70ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
oxytetracycline, anhydrous[no description available]medium30
rolitetracycline[no description available]medium10
thiolactomycin[no description available]medium10
3,4,5-trihydroxybenzamidoxime[no description available]medium10benzenetriol
ethylene glycol[no description available]medium20ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
inositol[no description available]medium20cyclitol;
hexol
melatonin[no description available]medium90acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
niacin[no description available]medium50pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
pyrazinamide[no description available]medium40monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug
pyridoxine[no description available]medium70hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thiamine[no description available]medium40primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2,4-dinitrophenol[no description available]medium60dinitrophenolallergen;
antiseptic drug;
bacterial xenobiotic metabolite;
geroprotector;
oxidative phosphorylation inhibitor
3-methylcholanthrene[no description available]medium20ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
acetohexamide[no description available]medium20acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
albendazole[no description available]medium30aryl sulfide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		anthelminthic drug;
microtubule-destabilising agent;
tubulin modulator
benzbromarone[no description available]medium501-benzofurans;
aromatic ketone		uricosuric drug
bithionol[no description available]medium20aryl sulfide;
bridged diphenyl antifungal drug;
bridged diphenyl fungicide;
dichlorobenzene;
organochlorine pesticide;
polyphenol		antifungal agrochemical;
antiplatyhelmintic drug
candesartan[no description available]medium40benzimidazolecarboxylic acid;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
chlorzoxazone[no description available]medium401,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound		muscle relaxant;
sedative
ciglitazone[no description available]medium20aromatic ether;
thiazolidinone		antineoplastic agent;
insulin-sensitizing drug
cromolyn[no description available]medium30chromones;
dicarboxylic acid		anti-asthmatic drug;
calcium channel blocker
diethylcarbamazine[no description available]medium20N-carbamoylpiperazine;
N-methylpiperazine
carbonyl cyanide p-trifluoromethoxyphenylhydrazone[no description available]high60aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore
fenofibrate[no description available]medium50aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
glafenine[no description available]medium50aminoquinoline;
carboxylic ester;
glycol;
organochlorine compound;
secondary amino compound		inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
gliclazide[no description available]medium30N-sulfonylureahypoglycemic agent;
insulin secretagogue;
radical scavenger
hexachlorophene[no description available]medium30bridged diphenyl fungicide;
polyphenol;
trichlorobenzene		acaricide;
antibacterial agent;
antifungal agrochemical;
antiseptic drug
hycanthone[no description available]medium50thioxanthenesmutagen;
schistosomicide drug
iproniazid[no description available]medium120carbohydrazide;
pyridines
avapro[no description available]medium50azaspiro compound;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
isocarboxazid[no description available]medium90benzenes
leflunomide[no description available]medium50(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor
meclofenamate sodium anhydrous[no description available]medium20organic sodium salt
vitamin k 3[no description available]medium201,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
meprobamate[no description available]medium250organic molecular entity
meprobamate[no description available]medium252organic molecular entity
methapyrilene[no description available]medium40ethylenediamine derivativeanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative
nocodazole[no description available]medium50aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
metolazone[no description available]medium40organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor
nimesulide[no description available]medium40aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
oxibendazole[no description available]medium30benzimidazoles;
carbamate ester
4-dichlorobenzene[no description available]medium20dichlorobenzeneinsecticide
pargyline[no description available]medium110aromatic amine
pinacidil[no description available]medium40pyridines
pioglitazone[no description available]medium60aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic
probucol[no description available]medium50dithioketal;
polyphenol		anti-inflammatory drug;
anticholesteremic drug;
antilipemic drug;
antioxidant;
cardiovascular drug
sulfamethizole[no description available]medium40sulfonamide antibiotic;
sulfonamide;
thiadiazoles		antiinfective agent;
antimicrobial agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
gatifloxacin[no description available]medium20N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antiinfective agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
tolazamide[no description available]medium40N-sulfonylureahypoglycemic agent;
potassium channel blocker
tolmetin[no description available]medium40aromatic ketone;
monocarboxylic acid;
pyrroles		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
troglitazone[no description available]medium60chromanes;
thiazolidinone		anticoagulant;
anticonvulsant;
antineoplastic agent;
antioxidant;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
hypoglycemic agent;
platelet aggregation inhibitor;
vasodilator agent
pirinixic acid[no description available]medium20aryl sulfide;
organochlorine compound;
pyrimidines
oxyphenonium[no description available]medium30acylcholine
cephaloridine[no description available]medium20beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug
sorbitol[no description available]medium70glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
isoproterenol hydrochloride[no description available]medium20catechols
promazine hydrochloride[no description available]medium20hydrochloride
2-acetylaminofluorene[no description available]medium102-acetamidofluorenesantimitotic;
carcinogenic agent;
epitope;
mutagen
idoxuridine[no description available]medium40organoiodine compound;
pyrimidine 2'-deoxyribonucleoside		antiviral drug;
DNA synthesis inhibitor
isonicotinic acid[no description available]medium10pyridinemonocarboxylic acidalgal metabolite;
human metabolite
carbon tetrachloride[no description available]medium30chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
physostigmine[no description available]medium80carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
promethazine hydrochloride[no description available]medium20hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative
acetylcholine chloride[no description available]medium30quaternary ammonium salt
methoxamine hydrochloride[no description available]medium20dimethoxybenzene
dimethylnitrosamine[no description available]medium20nitrosaminegeroprotector;
mutagen
lactose[no description available]medium50lactose
primaquine phosphate[no description available]medium20
colchicine[no description available]medium370alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
gallamine triethiodide[no description available]medium20
uracil mustard[no description available]medium20aminouracil;
nitrogen mustard
dimethylformamide[no description available]medium10formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent
arginine[no description available]medium150arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
tromethamine[no description available]medium40primary amino compound;
triol		buffer
rotenone[no description available]medium90organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin
isosorbide dinitrate[no description available]medium40glucitol derivative;
nitrate ester		nitric oxide donor;
vasodilator agent
hexachlorobutadiene[no description available]medium10organochlorine compound
2-bromophenol[no description available]medium20bromophenolmarine metabolite
3-dinitrobenzene[no description available]medium20dinitrobenzeneneurotoxin
pyridostigmine bromide[no description available]medium30pyridinium salt
4,4'-diaminodiphenylmethane[no description available]medium20aromatic amineallergen;
carcinogenic agent
phenylisothiocyanate[no description available]medium20isothiocyanateallergen;
reagent
2-bromoethylamine[no description available]medium20
allyl alcohol[no description available]medium30primary allylic alcohol;
propenol		antibacterial agent;
fungicide;
herbicide;
insecticide;
plant metabolite
imipramine hydrochloride[no description available]medium20hydrochlorideantidepressant
mephobarbital[no description available]medium20barbituratesanticonvulsant
edrophonium chloride[no description available]medium20chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
di-n-pentyl phthalate[no description available]medium20diester;
phthalate ester		plasticiser
cinchophen[no description available]medium50quinolines
phenazopyridine hydrochloride[no description available]medium20hydrochloridecarcinogenic agent;
local anaesthetic;
non-narcotic analgesic
tetrracaine hydrochloride[no description available]medium20benzoate ester
diphenhydramine hydrochloride[no description available]medium20hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
tripelennamine hydrochloride[no description available]medium20
ethynodiol diacetate[no description available]medium30steroid ester;
terminal acetylenic compound		contraceptive drug;
estrogen receptor modulator;
synthetic oral contraceptive
hydrazine[no description available]medium60azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
monocrotaline[no description available]medium30pyrrolizidine alkaloid
pseudoephedrine hydrochloride[no description available]medium20hydrochlorideplant metabolite
procarbazine hydrochloride[no description available]medium20hydrochlorideantineoplastic agent
cyproterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin
amitriptyline hydrochloride[no description available]medium20organic tricyclic compound
1-naphthylisothiocyanate[no description available]medium20isothiocyanateinsecticide
isoxsuprine hydrochloride[no description available]medium20alkylbenzene
betaine hydrochloride[no description available]medium20
3-hydroxyacetanilide[no description available]medium20acetamides;
phenols		non-narcotic analgesic
methoxyacetic acid[no description available]medium20ether;
monocarboxylic acid		antineoplastic agent;
apoptosis inducer;
human xenobiotic metabolite;
mutagen
cyproheptadine hydrochloride (anhydrous)[no description available]medium20hydrochloride
pregnenolone carbonitrile[no description available]medium10aliphatic nitrile
ibufenac[no description available]medium40monocarboxylic acidEC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
hepatotoxic agent;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
2,3,7,8-tetrachlorodibenzodioxine[no description available]medium10polychlorinated dibenzodioxine
paraquat[no description available]medium30organic cationgeroprotector;
herbicide
clonidine hydrochloride[no description available]medium20dichlorobenzene
ethylene dimethanesulfonate[no description available]medium20
mexiletine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
beclomethasone dipropionate[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
enone;
glucocorticoid;
propanoate ester;
steroid ester		anti-arrhythmia drug;
anti-asthmatic drug;
anti-inflammatory drug;
prodrug
vidarabine[no description available]medium30beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
bacterial metabolite;
nucleoside antibiotic
metoclopramide hydrochloride[no description available]medium20
carbendazim[no description available]medium20benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent
ethionine[no description available]medium20S-ethylhomocysteineantimetabolite;
carcinogenic agent
disopyramide phosphate[no description available]medium20organoammonium phosphate
moricizine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
pirprofen[no description available]medium40pyrroline
serentil[no description available]medium20organosulfonate saltdopaminergic antagonist;
first generation antipsychotic
propafenone hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
carbidopa[no description available]medium30catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
cephradine[no description available]medium30beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug
ticrynafen[no description available]medium40aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic
bezafibrate[no description available]medium40aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
nonachlazine[no description available]medium10
flecainide acetate[no description available]medium20acetate saltanti-arrhythmia drug
nicardipine hydrochloride[no description available]medium20dihydropyridinegeroprotector
indacrinone[no description available]medium20
butoconazole nitrate[no description available]medium20aryl sulfide;
conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
organic nitrate salt
fialuridine[no description available]medium40
mitoxantrone hydrochloride[no description available]medium20hydrochlorideantineoplastic agent
atomoxetine[no description available]medium30aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
alpidem[no description available]medium60imidazoles
temafloxacin[no description available]medium20amino acid;
monocarboxylic acid;
N-arylpiperazine;
organofluorine compound;
quinolone antibiotic;
quinolone;
secondary amino compound;
tertiary amino compound
clinafloxacin[no description available]medium20quinolines
bromfenac[no description available]medium40aromatic amino acid;
benzophenones;
organobromine compound;
substituted aniline		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
tasosartan[no description available]medium40biphenyls
saquinavir monomethanesulfonate[no description available]medium20organic molecular entity
allyl formate[no description available]medium20
desferrioxamine b mesylate[no description available]medium20methanesulfonate saltantidote;
ferroptosis inhibitor;
iron chelator
bupropion hydrochloride[no description available]medium20aromatic ketone
trazodone hydrochloride[no description available]medium40hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
verapamil hydrochloride[no description available]medium30
ciprofloxacin hydrochloride anhydrous[no description available]medium20hydrochlorideantibacterial drug;
antiinfective agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
amantadine hydrochloride[no description available]medium20hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist
dobutamine hydrochloride[no description available]medium20hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
sulconazole, mononitrate, (+-)-isomer[no description available]medium20conazole antifungal drug;
imidazole antifungal drug;
organic nitrate salt
telmisartan[no description available]medium50benzimidazoles;
biphenyls;
carboxybiphenyl		angiotensin receptor antagonist;
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
environmental contaminant;
xenobiotic
trimethobenzamide monohydrochloride[no description available]medium20
amiloride hydrochloride[no description available]medium20hydratediuretic;
sodium channel blocker
econazole nitrate[no description available]medium20
lomefloxacin hydrochloride[no description available]medium20hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent
flunoxaprofen[no description available]medium201,3-benzoxazoles;
monocarboxylic acid;
organofluorine compound		antirheumatic drug;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
protein kinase C agonist
tianeptine[no description available]medium20dibenzothiazepine;
monocarboxylic acid;
organochlorine compound
loperamide hydrochloride[no description available]medium20hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
grepafloxacin[no description available]medium20fluoroquinolone antibiotic;
quinolines;
quinolone antibiotic
2-naphthylisothiocyanate[no description available]medium20
rosiglitazone[no description available]medium50aminopyridine;
thiazolidinediones		EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
insulin-sensitizing drug
chloroquine diphosphate[no description available]medium20
orphenadrine citrate[no description available]medium20citrate saltH1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
ketorolac tromethamine[no description available]medium20organoammonium saltanalgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor
n-(3,5-dichlorophenyl)succinimide[no description available]medium20pyrrolidines
phentolamine mesylate[no description available]medium20
oxybutynin hydrochloride[no description available]medium20hydrochloride
1-cyano-2-hydroxy-3-butene[no description available]medium10secondary alcohol
cordium[no description available]medium20hydrate;
hydrochloride
bosentan anhydrous[no description available]medium60primary alcohol;
pyrimidines;
sulfonamide		antihypertensive agent;
endothelin receptor antagonist
dilevalol[no description available]medium102-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide
nsc-141549[no description available]medium20
biotin[no description available]medium20biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
aflatoxin b1[no description available]medium20aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
fludrocortisone acetate[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
fluorinated steroid;
mineralocorticoid;
tertiary alpha-hydroxy ketone
vincristine sulfate[no description available]medium20organic sulfate saltantineoplastic agent;
geroprotector
acivicin[no description available]medium20isoxazoles;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		antileishmanial agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor;
glutamine antagonist;
metabolite
glucosamine[no description available]medium30D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
puromycin[no description available]medium30puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
moxalactam disodium[no description available]medium20
abacavir[no description available]medium502,6-diaminopurinesantiviral drug;
drug allergen;
HIV-1 reverse transcriptase inhibitor
mometasone furoate[no description available]medium2011beta-hydroxy steroid;
2-furoate ester;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
organochlorine compound;
steroid ester		anti-allergic agent;
anti-inflammatory drug
nortriptyline hydrochloride[no description available]medium20organic tricyclic compoundgeroprotector
erythromycin estolate[no description available]medium30aminoglycoside sulfate salt;
erythromycin derivative		enzyme inhibitor
kanamycin sulfate[no description available]medium20aminoglycoside sulfate saltantibacterial drug;
geroprotector
paromomycin sulfate[no description available]medium20
chloramphenicol palmitate[no description available]medium20hexadecanoate ester
calcium pantothenate[no description available]medium20polymer
doxorubicin hydrochloride[no description available]medium20anthracycline
maleic acid[no description available]medium20butenedioic acidalgal metabolite;
mouse metabolite;
plant metabolite
cyanoginosin lr[no description available]medium20microcystinbacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
environmental contaminant;
xenobiotic
cerivastatin[no description available]medium30dihydroxy monocarboxylic acid;
pyridines;
statin (synthetic)
drf 2725[no description available]medium20
azaserine[no description available]medium20carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
sodium bicarbonate[no description available]medium20one-carbon compound;
organic sodium salt		antacid;
food anticaking agent
arsenic trioxide[no description available]medium30arsenic oxideantineoplastic agent;
insecticide
idarubicin hydrochloride[no description available]medium20anthracycline
carbenoxolone sodium[no description available]medium30triterpenoid
methimazole[no description available]medium501,3-dihydroimidazole-2-thionesantithyroid drug
capsaicin[no description available]medium60capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
(1R,2S)-tranylcypromine hydrochloride[no description available]medium20hydrochloride
thioacetamide[no description available]medium20thiocarboxamidehepatotoxic agent
hmr 3647[no description available]medium40
tolcapone[no description available]medium602-nitrophenols;
benzophenones;
catechols		antiparkinson drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
retinol palmitate[no description available]medium20all-trans-retinyl ester;
retinyl palmitate		antioxidant;
Escherichia coli metabolite;
human xenobiotic metabolite
eprosartan[no description available]medium40dicarboxylic acid;
imidazoles;
thiophenes		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
montelukast[no description available]medium40aliphatic sulfide;
monocarboxylic acid;
quinolines		anti-arrhythmia drug;
anti-asthmatic drug;
leukotriene antagonist
timolol maleate[no description available]medium20maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
brompheniramine maleate[no description available]medium20maleate saltanti-allergic agent
chlorpheniramine maleate[no description available]medium20organic molecular entity
clemastine fumarate[no description available]medium20fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist
methylergonovine maleate[no description available]medium20ergoline alkaloidgeroprotector
entacapone[no description available]medium502-nitrophenols;
catechols;
monocarboxylic acid amide;
nitrile		antidyskinesia agent;
antiparkinson drug;
central nervous system drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
estradiol-17 beta-glucuronide[no description available]medium203-hydroxy steroid;
steroid glucosiduronic acid
cis-flupenthixol dihydrochloride[no description available]medium10hydrochloridegeroprotector
phenoxybenzamine hydrochloride[no description available]medium20organic molecular entity
acitretin[no description available]medium40acitretin;
alpha,beta-unsaturated monocarboxylic acid;
retinoid		keratolytic drug
furazolidone[no description available]medium20
octylmethoxycinnamate[no description available]medium20cinnamate ester
vinblastine sulfate[no description available]medium20
trientine hydrochloride[no description available]medium30
dextromethorphan hydrobromide[no description available]medium20hydrate;
hydrobromide
fenoterol[no description available]medium20hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
enclomiphene citrate[no description available]medium10
diphenoxylate hydrochloride[no description available]medium20hydrochlorideantidiarrhoeal drug
ergonovine maleate[no description available]medium20maleate saltdiagnostic agent;
oxytocic
dantrolene sodium[no description available]medium20
ursodoxicoltaurine[no description available]medium10bile acid taurine conjugateanti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent
molindone hydrochloride[no description available]medium20indoles
gentamicin sulfate[no description available]medium10
baci-im[no description available]medium40homodetic cyclic peptide;
polypeptide;
zwitterion		antibacterial agent;
antimicrobial agent
cytidine diphosphate choline[no description available]medium20nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
clindamycin hydrochloride[no description available]medium20S-glycosyl compound
quinine sulfate[no description available]medium20hydrate
cefotiam hydrochloride[no description available]medium20
potassium aminobenzoate[no description available]medium20
methicillin sodium[no description available]medium20organic sodium salt
nafcillin sodium[no description available]medium20organic sodium salt
penicillin g sodium[no description available]medium20organic sodium salt
cefamandole nafate[no description available]medium20organic sodium saltantibacterial drug
cephapirin sodium[no description available]medium20cephalosporin;
organic sodium salt		antibacterial drug
sodium cephalothin[no description available]medium20organic sodium salt
dicloxacillin sodium[no description available]medium20hydrate
azlocillin sodium[no description available]medium20organic sodium salt
acenocoumarol[no description available]medium20C-nitro compound;
hydroxycoumarin;
methyl ketone		anticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
isoxicam[no description available]medium20benzothiazine;
isoxazoles;
monocarboxylic acid amide		antirheumatic drug;
non-steroidal anti-inflammatory drug
chlortetracycline hydrochloride[no description available]medium20
methacycline monohydrochloride[no description available]medium20
minocycline hydrochloride[no description available]medium20
demeclocycline hydrochloride[no description available]medium20
folic acid[no description available]medium70folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
dacarbazine[no description available]medium50dacarbazine
citrovorum factor[no description available]medium30tetrahydrofolic acid
celecoxib[no description available]medium30organofluorine compound;
pyrazoles;
sulfonamide;
toluenes		cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
sulfobromophthalein[no description available]medium302-benzofurans;
organobromine compound;
organosulfonic acid;
phenols		dye
telenzepine[no description available]medium20benzodiazepine
temozolomide[no description available]medium30imidazotetrazine;
monocarboxylic acid amide;
triazene derivative		alkylating agent;
antineoplastic agent;
prodrug
diquat[no description available]medium10organic cationdefoliant;
herbicide
n-pentanoic acid[no description available]medium10short-chain fatty acid;
straight-chain saturated fatty acid		plant metabolite
tolrestat[no description available]medium40naphthalenesEC 1.1.1.21 (aldehyde reductase) inhibitor
diltiazem hydrochloride[no description available]medium10hydrochlorideantihypertensive agent;
calcium channel blocker;
vasodilator agent
gefitinib[no description available]medium40aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
cox 189[no description available]medium30amino acid;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
secondary amino compound		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
olmesartan[no description available]medium20biphenylyltetrazoleangiotensin receptor antagonist;
antihypertensive agent
lapatinib[no description available]medium50furans;
organochlorine compound;
organofluorine compound;
quinazolines		antineoplastic agent;
tyrosine kinase inhibitor
taurolithocholic acid[no description available]medium20bile acid taurine conjugate;
monocarboxylic acid amide		human metabolite
indinavir sulfate[no description available]medium10azaheterocycle sulfate salt
ximelagatran[no description available]medium30amidoxime;
azetidines;
carboxamide;
ethyl ester;
hydroxylamines;
secondary amino compound;
secondary carboxamide;
tertiary carboxamide		anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
prodrug;
serine protease inhibitor
ampicillin sodium[no description available]medium10organic sodium salt
mobic[no description available]medium301,3-thiazoles;
benzothiazine;
monocarboxylic acid amide		analgesic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
sudoxicam[no description available]medium10
imatinib[no description available]medium60aromatic amine;
benzamides;
N-methylpiperazine;
pyridines;
pyrimidines		antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor
n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid[no description available]medium10
nelfinavir[no description available]medium40aryl sulfide;
benzamides;
organic heterobicyclic compound;
phenols;
secondary alcohol;
tertiary amino compound		antineoplastic agent;
HIV protease inhibitor
amprenavir[no description available]medium40carbamate ester;
sulfonamide;
tetrahydrofuryl ester		antiviral drug;
HIV protease inhibitor
rosuvastatin[no description available]medium20dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrimidines;
statin (synthetic);
sulfonamide		anti-inflammatory agent;
antilipemic drug;
cardioprotective agent;
CETP inhibitor;
environmental contaminant;
xenobiotic
carisoprodol[no description available]medium30carbamate estermuscle relaxant
shamixanthone[no description available]medium10cyclic ketone;
phenols;
pyranoxanthene		metabolite
betaine[no description available]medium40amino-acid betaine;
glycine derivative		fundamental metabolite
ethanolamine[no description available]medium20ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
alaproclate[no description available]medium20alpha-amino acid ester
bendazac[no description available]medium20indazoles;
monocarboxylic acid		non-steroidal anti-inflammatory drug;
radical scavenger
bethanechol[no description available]medium40carbamate ester;
quaternary ammonium ion		muscarinic agonist
carbinoxamine[no description available]medium30monochlorobenzenes;
pyridines;
tertiary amino compound		anti-allergic agent;
antiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist
cyclofenil[no description available]medium20organic molecular entity
deferoxamine[no description available]medium100acyclic desferrioxaminebacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore
isoproterenol[no description available]medium430catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
meclizine[no description available]medium60diarylmethane
metaproterenol[no description available]medium30aralkylamino compound;
phenylethanolamines;
resorcinols;
secondary alcohol;
secondary amino compound
metyrapone[no description available]medium30aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
moxisylyte[no description available]medium20monoterpenoid
nialamide[no description available]medium80organonitrogen compound;
organooxygen compound
succinylcholine[no description available]medium50quaternary ammonium ion;
succinate ester		drug allergen;
muscle relaxant;
neuromuscular agent
sulfamethoxazole[no description available]medium20isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
tranexamic acid[no description available]medium20amino acid
mitomycin[no description available]medium20mitomycinalkylating agent;
antineoplastic agent
prednisolone[no description available]medium3011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic
oxandrolone[no description available]medium2017beta-hydroxy steroid;
3-oxo steroid;
anabolic androgenic steroid;
oxa-steroid		anabolic agent;
androgen
kanamycin a[no description available]medium20kanamycinsbacterial metabolite
mebanazine[no description available]medium20benzenes
benziodarone[no description available]medium20aromatic ketone
benzonatate[no description available]medium30benzoate ester;
secondary amino compound;
substituted aniline		anaesthetic;
antitussive
framycetin[no description available]medium90aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
edrophonium bromide[no description available]medium10
dihydroergotamine[no description available]medium20ergot alkaloid;
semisynthetic derivative		dopamine agonist;
non-narcotic analgesic;
serotonergic agonist;
sympatholytic agent;
vasoconstrictor agent
lactulose[no description available]medium20glycosylfructosegastrointestinal drug;
laxative
isosorbide[no description available]medium10organic molecular entity
clomacran[no description available]medium30acridines
clomacran[no description available]medium31acridines
clemastine[no description available]medium20monochlorobenzenes;
N-alkylpyrrolidine		anti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist
cromolyn sodium[no description available]medium10organic sodium saltanti-asthmatic drug;
drug allergen
fenclozic acid[no description available]medium30
laxagetten 4,4'-diacetoxydiphenylpyridylemethane[no description available]medium20
alclofenac[no description available]medium20aromatic ether;
monocarboxylic acid;
monochlorobenzenes		drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
oxyphenisatin[no description available]medium20indoles
clometacin[no description available]medium20N-acylindole
exifone[no description available]medium20benzophenones
oseltamivir[no description available]medium30acetamides;
amino acid ester;
cyclohexenecarboxylate ester;
primary amino compound		antiviral drug;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
environmental contaminant;
prodrug;
xenobiotic
tilbroquinol[no description available]medium20organohalogen compound;
quinolines
ebrotidine[no description available]medium20sulfonamide
isaxonine[no description available]medium20aminopyrimidine
fenoxypropazine[no description available]medium20aromatic ether
nitrefazole[no description available]medium20imidazoles
tamsulosin[no description available]medium205-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamidealpha-adrenergic antagonist;
antineoplastic agent
pralnacasan[no description available]medium20
paromomycin[no description available]medium30amino cyclitol glycoside;
aminoglycoside antibiotic		anthelminthic drug;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug
fiduxosin[no description available]medium20
deferasirox[no description available]medium20benzoic acids;
monocarboxylic acid;
phenols;
triazoles		iron chelator
benzarone[no description available]medium201-benzofurans
tenofovir[no description available]medium30nucleoside analogue;
phosphonic acids		antiviral drug;
drug metabolite;
HIV-1 reverse transcriptase inhibitor
aplaviroc[no description available]medium20
maraviroc[no description available]medium20tropane alkaloid
toremifene[no description available]medium30aromatic ether;
organochlorine compound;
tertiary amine		antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
orlistat[no description available]medium30beta-lactone;
carboxylic ester;
formamides;
L-leucine derivative		anti-obesity agent;
bacterial metabolite;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor
alatrofloxacin[no description available]medium10
oxymetholone[no description available]medium20
benzphetamine[no description available]medium20amphetamines;
tertiary amine		adrenergic uptake inhibitor;
appetite depressant;
dopamine uptake inhibitor;
sympathomimetic agent
su 11248[no description available]medium30monocarboxylic acid amide;
pyrroles		angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
immunomodulator;
neuroprotective agent;
vascular endothelial growth factor receptor antagonist
pafuramidine[no description available]medium20
lu 208075[no description available]medium20diarylmethane
bibx 1382bs[no description available]medium20substituted aniline
chlorhexidine[no description available]medium30biguanides;
monochlorobenzenes		antibacterial agent;
antiinfective agent
pazopanib[no description available]medium20aminopyrimidine;
indazoles;
sulfonamide		angiogenesis modulating agent;
antineoplastic agent;
tyrosine kinase inhibitor;
vascular endothelial growth factor receptor antagonist
tipranavir[no description available]medium30sulfonamideantiviral drug;
HIV protease inhibitor
amg531[no description available]medium10
1-amino-9,10-dioxo-4-(3-sulfamoylanilino)anthracene-2-sulfonic acid[no description available]medium10
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamide[no description available]medium10pyridopyrimidine
4,5-dimethoxy-2-nitrobenzaldehyde[no description available]medium10aromatic ether;
C-nitro compound
schizandrin b[no description available]medium10
wortmannin[no description available]medium30acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
nu 6027[no description available]medium10
ku 55933[no description available]medium10
ic 86621[no description available]medium10aromatic ketone
nu 7441[no description available]medium10dibenzothiophenes
ku-0060648[no description available]medium10dibenzothiophenes
ve 821[no description available]medium10aromatic amide
carnitine[no description available]medium30amino-acid betainehuman metabolite;
mouse metabolite
coumarin[no description available]medium20coumarinsfluorescent dye;
human metabolite;
plant metabolite
guaiacol[no description available]medium20guaiacolsdisinfectant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
expectorant;
plant metabolite
histamine[no description available]medium180aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
histamine[no description available]medium181aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
enprofylline[no description available]medium30oxopurineanti-arrhythmia drug;
anti-asthmatic drug;
bronchodilator agent;
non-steroidal anti-inflammatory drug
acetarsol[no description available]medium10acetamides;
anilide
ethacridine[no description available]medium10acridines
4-(acetylamino)benzeneacetic acid[no description available]medium10acetamides;
anilide
adiphenine[no description available]medium10diarylmethane
aklomide[no description available]medium10carbonyl compound;
organohalogen compound
p-aminohippuric acid[no description available]medium40N-acylglycineDaphnia magna metabolite
amodiaquine[no description available]medium20aminoquinoline;
organochlorine compound;
phenols;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
drug allergen;
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug
amprolium[no description available]medium10pyridinium ioncoccidiostat
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol[no description available]medium10aporphine alkaloid
arecoline[no description available]medium20enoate ester;
methyl ester;
pyridine alkaloid;
tetrahydropyridine		metabolite;
muscarinic agonist
bendroflumethiazide[no description available]medium30benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benserazide[no description available]medium10carbohydrazide;
catechols;
primary alcohol;
primary amino compound		antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
benzothiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
bisacodyl[no description available]medium30diarylmethane
seratrodast[no description available]medium10organic molecular entity
carbamylcholine[no description available]medium10
chloroxylenol[no description available]medium20monochlorobenzenes;
phenols		antiseptic drug;
disinfectant;
molluscicide
aricine[no description available]medium10cinchona alkaloid
cloxyquin[no description available]medium10organochlorine compound;
quinolines
cyclandelate[no description available]medium10carboxylic ester;
secondary alcohol		vasodilator agent
dibenzothiophene[no description available]medium10dibenzothiophenes;
mancude organic heterotricyclic parent		keratolytic drug
dichlorphenamide[no description available]medium20dichlorobenzene;
sulfonamide		antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
ophthalmology drug
dilacor xr[no description available]medium10acetate ester;
aromatic ether;
benzothiazepine;
lactam;
tertiary amino compound
dimethadione[no description available]medium10oxazolidinone
dyclonine[no description available]medium10aromatic ketone;
piperidines		topical anaesthetic
dyphylline[no description available]medium20oxopurine;
propane-1,2-diols		bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
muscle relaxant;
vasodilator agent
ebselen[no description available]medium20benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger
profenamine[no description available]medium20phenothiazines;
tertiary amino compound		adrenergic antagonist;
antidyskinesia agent;
antiparkinson drug;
histamine antagonist;
muscarinic antagonist
ethotoin[no description available]medium20imidazolidine-2,4-dioneanticonvulsant
fenoldopam[no description available]high30benzazepinealpha-adrenergic agonist;
antihypertensive agent;
dopamine agonist;
dopaminergic antagonist;
vasodilator agent
guaifenesin[no description available]medium20methoxybenzenes
hexoprenaline[no description available]medium10
hexamethylene bisacetamide[no description available]medium10acetamides
hydralazine[no description available]medium40azaarene;
hydrazines;
ortho-fused heteroarene;
phthalazines		antihypertensive agent;
vasodilator agent
hydroflumethiazide[no description available]medium30benzothiadiazine;
thiazide		antihypertensive agent;
diuretic
iodoquinol[no description available]medium10monohydroxyquinoline;
organoiodine compound		antiamoebic agent;
antibacterial agent;
antiprotozoal drug;
antiseptic drug
isoetharine[no description available]medium10catecholamine
isoxsuprine[no description available]medium20alkylbenzene
letrozole[no description available]medium20nitrile;
triazoles		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
ly 171883[no description available]medium10acetophenones;
aromatic ether;
phenols;
tetrazoles		anti-asthmatic drug;
leukotriene antagonist
mephenesin[no description available]medium10aromatic ether;
glycerol ether
methocarbamol[no description available]medium30aromatic ether;
carbamate ester;
secondary alcohol
mitotane[no description available]medium20diarylmethane
acecainide[no description available]medium10acetamides;
benzamides		anti-arrhythmia drug
nadolol[no description available]medium20tetralins
nafronyl[no description available]medium10naphthalenes
naftopidil[no description available]medium10piperazines
naphazoline[no description available]medium10naphthalenes
neostigmine[no description available]medium20quaternary ammonium ionantidote to curare poisoning;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
nilvadipine[no description available]medium10dihydropyridine;
isopropyl ester;
methyl ester;
nitrile
nitromide[no description available]medium10
6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one[no description available]medium10isoquinolines
nylidrin[no description available]medium10alkylbenzene
phenacemide[no description available]medium10acetamides
1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate[no description available]medium10pyrroloindole
piracetam[no description available]medium10organonitrogen compound;
organooxygen compound
pirenzepine[no description available]medium20pyridobenzodiazepineanti-ulcer drug;
antispasmodic drug;
muscarinic antagonist
piretanide[no description available]medium10aromatic ether
duodote[no description available]medium20pyridinium ionantidote to organophosphate poisoning;
antidote to sarin poisoning;
cholinergic drug;
cholinesterase reactivator
rofecoxib[no description available]medium10butenolide;
sulfone		analgesic;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
roxarsone[no description available]medium102-nitrophenols;
organoarsonic acid		agrochemical;
animal growth promotant;
antibacterial drug;
coccidiostat
salicylsalicylic acid[no description available]medium20benzoate ester;
benzoic acids;
phenols;
salicylates		antineoplastic agent;
antirheumatic drug;
EC 3.5.2.6 (beta-lactamase) inhibitor;
hypoglycemic agent;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
succinylsulfathiazole[no description available]medium101,3-thiazoles
sulfamerazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen
sulfamethazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antiinfective agent;
antimicrobial agent;
carcinogenic agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
ligand;
xenobiotic
sulfisoxazole[no description available]medium10isoxazoles;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
drug allergen
tetrahydroxy-1,4-quinone[no description available]medium10hydroxybenzoquinonekeratolytic drug
thalidomide[no description available]medium70phthalimides;
piperidones
thiabendazole[no description available]medium201,3-thiazoles;
benzimidazole fungicide;
benzimidazoles		antifungal agrochemical;
antinematodal drug
2-thiosalicylic acid[no description available]medium10sulfanylbenzoic acidantipyretic;
non-narcotic analgesic
tolazoline[no description available]medium10imidazolesalpha-adrenergic antagonist;
antihypertensive agent;
vasodilator agent
tolnaftate[no description available]medium10monothiocarbamic esterantifungal drug
trapidil[no description available]medium10triazolopyrimidines
trimebutine[no description available]medium20trihydroxybenzoic acid
trioxsalen[no description available]medium10psoralensdermatologic drug;
photosensitizing agent
tropicamide[no description available]medium10acetamides
tulobuterol[no description available]medium10organochlorine compound
urapidil[no description available]medium10piperazines
urethane[no description available]medium20carbamate esterfungal metabolite;
mutagen
xylazine[no description available]medium101,3-thiazine;
methylbenzene;
secondary amino compound		alpha-adrenergic agonist;
analgesic;
emetic;
muscle relaxant;
sedative
piperonyl butoxide[no description available]medium10benzodioxolespesticide synergist
penicillin g[no description available]medium20penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope
metaraminol[no description available]medium10phenylethanolaminesalpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent
pentylenetetrazole[no description available]medium80organic heterobicyclic compound;
organonitrogen heterocyclic compound
pentylenetetrazole[no description available]medium81organic heterobicyclic compound;
organonitrogen heterocyclic compound
apomorphine[no description available]medium350aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
ethopabate[no description available]medium10amidobenzoic acid
cysteamine[no description available]medium20amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
methoxamine[no description available]medium10amphetaminesalpha-adrenergic agonist;
antihypotensive agent
cloxacillin[no description available]medium20penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug
zoxazolamine[no description available]medium30benzoxazole
berlition[no description available]medium10dithiolanes;
heterocyclic fatty acid;
lipoic acid;
thia fatty acid		cofactor;
nutraceutical;
prosthetic group
cycloserine[no description available]medium204-amino-1,2-oxazolidin-3-one;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic;
zwitterion		antiinfective agent;
antimetabolite;
antitubercular agent;
metabolite;
NMDA receptor agonist
mepenzolate bromide[no description available]medium10diarylmethane
pantothenic acid[no description available]medium10pantothenic acid;
vitamin B5		antidote to curare poisoning;
geroprotector;
human blood serum metabolite
sulfachlorpyridazine[no description available]medium10organochlorine compound;
pyridazines;
sulfonamide		antibacterial drug;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
phensuximide[no description available]medium10pyrrolidines
synephrine[no description available]medium10ethanolamines;
phenethylamine alkaloid;
phenols		alpha-adrenergic agonist;
plant metabolite
chloroprocaine[no description available]medium10benzoate ester;
monochlorobenzenes		central nervous system depressant;
local anaesthetic;
peripheral nervous system drug
propantheline bromide[no description available]medium10xanthenes
fluorometholone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
dihydralazine[no description available]medium10phthalazines
dimenhydrinate[no description available]medium30diarylmethane
4-(benzoylamino)-2-hydroxybenzoic acid[no description available]medium10benzamides
trimetozine[no description available]medium10morpholines
docosanol[no description available]medium10docosanol;
long-chain primary fatty alcohol		antiviral drug;
plant metabolite
tetramethylpyrazine[no description available]medium10alkaloid;
pyrazines		antineoplastic agent;
apoptosis inhibitor;
bacterial metabolite;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
flurandrenolone[no description available]medium1021-hydroxy steroid
amiloride[no description available]medium250aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker
flumethasone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
floxacillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
(1S,2R)-tranylcypromine[no description available]medium102-phenylcyclopropan-1-amine
parbendazole[no description available]medium10benzimidazoles;
carbamate ester
metergoline[no description available]medium10carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist
capobenic acid[no description available]medium10benzamides
diftalone[no description available]medium10
carbimazole[no description available]medium201,3-dihydroimidazole-2-thiones;
carbamate ester		antithyroid drug;
prodrug
rose bengal b disodium salt[no description available]medium10
carbidopa[no description available]medium20catechols;
hydrazines;
monocarboxylic acid		antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
indalpine[no description available]medium10indoles
lidamidine[no description available]medium10ureas
talniflumate[no description available]medium10benzofurans
dazoxiben[no description available]medium10
remoxipride[no description available]medium30dimethoxybenzene
dopexamine[no description available]medium10catecholamine
lonapalene[no description available]medium10naphthalenes;
organochlorine compound
ipsapirone[no description available]medium10N-arylpiperazine
sematilide[no description available]medium10
remacemide[no description available]medium10stilbenoid
paroxetine hydrochloride[no description available]medium10hydrochlorideantidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor
proxicromil[no description available]medium10
torbafylline[no description available]medium10
enrofloxacin[no description available]medium10cyclopropanes;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		antibacterial agent;
antimicrobial agent;
antineoplastic agent
uk 68798[no description available]medium20aromatic ether;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
potassium channel blocker
mepindolol[no description available]medium10indoles
fpl 52791[no description available]medium10
epanolol[no description available]medium10acetamides
levcromakalim[no description available]medium101-benzopyran
hexylcaine hydrochloride[no description available]medium10
imipenem, anhydrous[no description available]medium10beta-lactam antibiotic allergen;
carbapenems;
zwitterion		antibacterial drug
sr141716[no description available]medium10amidopiperidine;
carbohydrazide;
dichlorobenzene;
monochlorobenzenes;
pyrazoles		anti-obesity agent;
appetite depressant;
CB1 receptor antagonist
fpl 55712[no description available]medium10aromatic ketone
sivelestat[no description available]medium20N-acylglycine;
pivalate ester
fpl-52694[no description available]medium10
ramatroban[no description available]medium10organic molecular entity
xaliproden[no description available]medium10(trifluoromethyl)benzenes;
naphthalenes;
tertiary amino compound;
tetrahydropyridine		serotonergic agonist
n-isobutyrylcysteine[no description available]medium10
dexpanthenol[no description available]medium20amino alcohol;
monocarboxylic acid amide		cholinergic drug;
provitamin
quilostigmine[no description available]medium10pyrroloindole
imiloxan[no description available]medium10benzodioxine
aspartame[no description available]medium10carboxylic acid;
dipeptide zwitterion;
dipeptide;
methyl ester		apoptosis inhibitor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
environmental contaminant;
micronutrient;
nutraceutical;
sweetening agent;
xenobiotic
tempol[no description available]medium10aminoxyls;
hydroxypiperidine		anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
catalyst;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
radical scavenger
vatalanib[no description available]medium10monochlorobenzenes;
phthalazines;
pyridines;
secondary amino compound		angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist
moxifloxacin[no description available]medium20aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug
clevidipine[no description available]medium20dihydropyridine
hyoscyamine[no description available]medium10tropane alkaloid
lactitol[no description available]medium10glycosyl alditolcathartic;
excipient;
laxative
fpl 52757[no description available]medium10
fpl 59257[no description available]medium10
erlotinib[no description available]medium30aromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound		antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor
zeneca zd 6169[no description available]medium10
sibenadet[no description available]medium10
latrepirdine[no description available]medium10methylpyridines;
pyridoindole		geroprotector
ramelteon[no description available]medium20indanes
sorafenib[no description available]medium30(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide		angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor
cortisone[no description available]medium2011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
phenethicillin[no description available]medium10penicillin allergen;
penicillin
ouabain[no description available]medium22011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
salicin[no description available]medium10aromatic primary alcohol;
aryl beta-D-glucoside;
benzyl alcohols		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
linezolid[no description available]high40acetamides;
morpholines;
organofluorine compound;
oxazolidinone		antibacterial drug;
protein synthesis inhibitor
(S)-bicalutamide[no description available]medium10N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
devazepide[no description available]medium101,4-benzodiazepinone;
indolecarboxamide		antineoplastic agent;
apoptosis inducer;
cholecystokinin antagonist;
gastrointestinal drug
halcinonide[no description available]medium10organic molecular entitySMO receptor agonist
metrizamide[no description available]medium10amino sugar
methylthiouracil[no description available]medium10pyrimidone
crotamiton[no description available]medium10
scopolamine[no description available]medium103-hydroxy carboxylic acid
ranitidine[no description available]medium30C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
almokalant[no description available]medium10
vx-745[no description available]medium10aryl sulfide;
dichlorobenzene;
difluorobenzene;
pyrimidopyridazine		anti-inflammatory drug;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
deracoxib[no description available]medium10organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
dasatinib[no description available]medium301,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
2-aminohippuric acid[no description available]medium10N-acylglycine
rs-130830[no description available]medium10
sitagliptin[no description available]medium30triazolopyrazine;
trifluorobenzene		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
environmental contaminant;
hypoglycemic agent;
serine proteinase inhibitor;
xenobiotic
vitamin k semiquinone radical[no description available]medium40
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
pheniramine maleate[no description available]medium10organic molecular entity
homatropine[no description available]medium10tropane alkaloid
levetiracetam[no description available]medium20pyrrolidin-2-onesanticonvulsant;
environmental contaminant;
xenobiotic
ar c67085mx[no description available]medium10
desoximetasone[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
sb 223412[no description available]medium10
enalaprilat anhydrous[no description available]medium20dicarboxylic acid;
dipeptide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
tiotropium[no description available]medium10
nw 1029[no description available]medium10
ici d1542[no description available]medium10
gavestinel[no description available]medium10
tipredane[no description available]medium103-hydroxy steroidandrogen
bentiromide[no description available]medium10dipeptidediagnostic agent;
indicator;
reagent
gemifloxacin[no description available]medium201,8-naphthyridine derivative;
fluoroquinolone antibiotic;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
topoisomerase IV inhibitor
utibapril[no description available]medium10
zd 9379[no description available]medium10
ly 450139[no description available]medium20peptide
cangrelor[no description available]medium10adenosine 5'-phosphate;
aryl sulfide;
nucleoside triphosphate analogue;
organochlorine compound;
organofluorine compound;
secondary amino compound		P2Y12 receptor antagonist;
platelet aggregation inhibitor
sch 527123[no description available]medium10
linaprazan[no description available]medium10
lecozotan[no description available]medium10
ar c155858[no description available]medium10
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one[no description available]medium10methoxybenzenes;
substituted aniline
azd 7545[no description available]medium10benzamides;
monochlorobenzenes;
organofluorine compound;
secondary carboxamide;
sulfone;
tertiary alcohol;
tertiary carboxamide		EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor;
hypoglycemic agent
clavulanate potassium[no description available]medium10potassium saltantibacterial drug;
antimicrobial agent;
EC 3.5.2.6 (beta-lactamase) inhibitor
cytomel[no description available]medium10organic sodium salt
a 967079[no description available]medium10
pht 427[no description available]medium10
dicumarol[no description available]medium20hydroxycoumarinanticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
Hsp90 inhibitor;
vitamin K antagonist
sildenafil[no description available]medium20piperazines;
pyrazolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
leucovorin[no description available]medium20formyltetrahydrofolic acidEscherichia coli metabolite;
mouse metabolite
carbadox[no description available]medium10quinoxaline derivative
fenobam[no description available]medium10ureas
clobetasol propionate[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid		anti-inflammatory drug
rifamycin sv[no description available]medium10acetate ester;
cyclic ketal;
lactam;
macrocycle;
organic heterotetracyclic compound;
polyphenol;
rifamycins		antimicrobial agent;
antitubercular agent;
bacterial metabolite
etomoxir[no description available]medium10aromatic ether
cp 724714[no description available]medium102-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamideantineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
hepatotoxic agent
carbonyl cyanide m-chlorophenyl hydrazone[no description available]medium70hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore
trifluoromethylphenothiazine[no description available]medium10phenothiazines
chloroxine[no description available]medium10monohydroxyquinoline;
organochlorine compound		antibacterial agent;
antifungal drug;
antiseborrheic
trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride[no description available]medium10
levormeloxifene[no description available]medium10
mevastatin[no description available]medium302-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite
artemisinin[no description available]medium40organic peroxide;
sesquiterpene lactone		antimalarial;
plant metabolite
fulvestrant[no description available]high3017beta-hydroxy steroid;
3-hydroxy steroid;
organofluorine compound;
sulfoxide		antineoplastic agent;
estrogen antagonist;
estrogen receptor antagonist
bazedoxifene[no description available]medium10phenylindole
lasofoxifene[no description available]medium10aromatic ether;
N-alkylpyrrolidine;
naphthols;
tetralins		antineoplastic agent;
bone density conservation agent;
cardioprotective agent;
estrogen receptor agonist;
estrogen receptor antagonist
pitavastatin[no description available]medium20cyclopropanes;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
quinolines;
statin (synthetic)		antioxidant
tan 67[no description available]medium10quinolines
alfuzosin[no description available]medium10monocarboxylic acid amide;
quinazolines;
tetrahydrofuranol		alpha-adrenergic antagonist;
antihypertensive agent;
antineoplastic agent
alosetron[no description available]medium10imidazoles;
pyridoindole		antiemetic;
gastrointestinal drug;
serotonergic antagonist
ambenonium[no description available]medium10quaternary ammonium ionEC 3.1.1.8 (cholinesterase) inhibitor
diatrizoic acid[no description available]medium10acetamides;
benzoic acids;
organoiodine compound		environmental contaminant;
radioopaque medium;
xenobiotic
secbutabarbital[no description available]medium10barbiturates
chlorambucil[no description available]medium10aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
chlorcyclizine[no description available]medium10diarylmethane
chlorothiazide[no description available]medium20benzothiadiazineantihypertensive agent;
diuretic
cilostazol[no description available]medium10lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
clonazepam[no description available]medium601,4-benzodiazepinone;
monochlorobenzenes		anticonvulsant;
anxiolytic drug;
GABA modulator
amphetamine[no description available]medium320primary amine
amphetamine[no description available]medium321primary amine
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
doxapram[no description available]medium30morpholines;
pyrrolidin-2-ones		central nervous system stimulant
edrophonium[no description available]medium10phenols;
quaternary ammonium ion		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
flurazepam[no description available]medium201,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
tertiary amino compound		anticonvulsant;
anxiolytic drug;
GABAA receptor agonist;
sedative
fomepizole[no description available]medium10pyrazolesantidote;
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
protective agent
2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1,1-dimethyl-3-pyrrolidin-1-iumyl) ester[no description available]medium10benzenes
guanidine[no description available]medium20carboxamidine;
guanidines;
one-carbon compound
hydroxychloroquine[no description available]medium20aminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug
mepenzolate[no description available]medium10diarylmethane
methadone[no description available]medium50benzenes;
diarylmethane;
ketone;
tertiary amino compound
methadone[no description available]medium51benzenes;
diarylmethane;
ketone;
tertiary amino compound
methazolamide[no description available]medium20sulfonamide;
thiadiazoles
methoxsalen[no description available]medium20aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite
methyclothiazide[no description available]medium10benzothiadiazine
milrinone[no description available]medium20bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
modafinil[no description available]medium10monocarboxylic acid amide;
sulfoxide
naratriptan[no description available]medium10heteroarylpiperidine;
sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
polythiazide[no description available]medium10benzothiadiazine
propantheline[no description available]medium20xanthenes
pyridostigmine[no description available]medium10pyridinium ion
rizatriptan[no description available]medium10tryptaminesanti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
ropinirole[no description available]medium10indolones;
tertiary amine		antidyskinesia agent;
antiparkinson drug;
central nervous system drug;
dopamine agonist
vorinostat[no description available]medium10dicarboxylic acid diamide;
hydroxamic acid		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor
tinidazole[no description available]medium10imidazolesantiamoebic agent;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug
trimethobenzamide[no description available]medium20benzamides;
tertiary amino compound		antiemetic
tyramine[no description available]medium80monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
delavirdine[no description available]medium20aminopyridine;
indolecarboxamide;
N-acylpiperazine;
sulfonamide		antiviral drug;
HIV-1 reverse transcriptase inhibitor
vigabatrin[no description available]medium10gamma-amino acidanticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
zaleplon[no description available]medium10nitrile;
pyrazolopyrimidine		anticonvulsant;
anxiolytic drug;
central nervous system depressant;
sedative
zonisamide[no description available]medium101,2-benzoxazoles;
sulfonamide		anticonvulsant;
antioxidant;
central nervous system drug;
protective agent;
T-type calcium channel blocker
cortisone acetate[no description available]medium10corticosteroid hormone
dextroamphetamine[no description available]medium2201-phenylpropan-2-amineadrenergic agent;
adrenergic uptake inhibitor;
dopamine uptake inhibitor;
dopaminergic agent;
neurotoxin;
sympathomimetic agent
cysteine[no description available]medium10cysteine zwitterion;
cysteine;
L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
flour treatment agent;
human metabolite
glutamine[no description available]medium30amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
methyltestosterone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
enone		anabolic agent;
androgen;
antineoplastic agent
edetic acid[no description available]medium210ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
calcium acetate[no description available]medium10calcium saltchelator
methionine[no description available]medium60aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
oxacillin[no description available]medium10penicillinantibacterial agent;
antibacterial drug
perflutren[no description available]medium10fluoroalkane;
fluorocarbon
fluoxymesterone[no description available]medium1011beta-hydroxy steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid;
fluorinated steroid		anabolic agent;
antineoplastic agent
methsuximide[no description available]medium10organic molecular entity
diethylpropion[no description available]medium10aromatic ketone;
tertiary amine		appetite depressant
methylergonovine[no description available]medium10ergoline alkaloid
aminophylline[no description available]medium40mixturebronchodilator agent;
cardiotonic drug
galantamine[no description available]medium10benzazepine alkaloid fundamental parent;
benzazepine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		antidote to curare poisoning;
cholinergic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant metabolite
nandrolone decanoate[no description available]medium10steroid ester
4-hydroxybutyric acid[no description available]medium104-hydroxy monocarboxylic acid;
hydroxybutyric acid		general anaesthetic;
GHB receptor agonist;
neurotoxin;
sedative
methamphetamine[no description available]medium30amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
pamabrom[no description available]medium10
diphenoxylate[no description available]medium20ethyl ester;
nitrile;
piperidinecarboxylate ester;
tertiary amine		antidiarrhoeal drug
metaxalone[no description available]medium10aromatic ether
spectinomycin[no description available]medium10cyclic acetal;
cyclic hemiketal;
cyclic ketone;
pyranobenzodioxin;
secondary alcohol;
secondary amino compound		antibacterial drug;
antimicrobial agent;
bacterial metabolite
dexbrompheniramine[no description available]medium10brompheniramineanti-allergic agent;
H1-receptor antagonist
megestrol[no description available]medium1017alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
tertiary alpha-hydroxy ketone		antineoplastic agent;
appetite enhancer;
contraceptive drug;
progestin;
synthetic oral contraceptive
carbenicillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
methenamine hippurate[no description available]medium10N-acylglycine
sodium thiosulfate[no description available]medium10inorganic sodium saltantidote to cyanide poisoning;
antifungal drug;
nephroprotective agent
fludarabine phosphate[no description available]medium10nucleoside analogue;
organofluorine compound;
purine arabinonucleoside monophosphate		antimetabolite;
antineoplastic agent;
antiviral agent;
DNA synthesis inhibitor;
immunosuppressive agent;
prodrug
fludrocortisone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
fluorinated steroid;
mineralocorticoid		adrenergic agent;
anti-inflammatory drug
oxcarbazepine[no description available]medium10cyclic ketone;
dibenzoazepine		anticonvulsant;
drug allergen
amikacin[no description available]medium10alpha-D-glucoside;
amino cyclitol glycoside;
aminoglycoside;
carboxamide		antibacterial drug;
antimicrobial agent;
nephrotoxin
vecuronium[no description available]medium10acetate ester;
androstane;
quaternary ammonium ion		drug allergen;
muscle relaxant;
neuromuscular agent;
nicotinic antagonist
mefloquine[no description available]medium20[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanolantimalarial
nitazoxanide[no description available]medium20benzamides;
carboxylic ester
acarbose[no description available]medium10tetrasaccharide derivativeEC 3.2.1.1 (alpha-amylase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
geroprotector;
hypoglycemic agent
miglustat[no description available]medium10piperidines;
tertiary amino compound		anti-HIV agent;
EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
haloperidol decanoate[no description available]medium10organic molecular entity
balsalazide[no description available]medium10
ranolazine[no description available]medium20aromatic amide;
monocarboxylic acid amide;
monomethoxybenzene;
N-alkylpiperazine;
secondary alcohol
adefovir[no description available]medium206-aminopurines;
ether;
phosphonic acids		antiviral drug;
DNA synthesis inhibitor;
drug metabolite;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent
aromasil[no description available]medium1017-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor;
environmental contaminant;
xenobiotic
clopidogrel[no description available]medium10methyl ester;
monochlorobenzenes;
thienopyridine		anticoagulant;
P2Y12 receptor antagonist;
platelet aggregation inhibitor
tiagabine[no description available]medium10beta-amino acid;
piperidinemonocarboxylic acid;
tertiary amino compound;
thiophenes		anticonvulsant;
GABA reuptake inhibitor
duloxetine[no description available]medium10duloxetine
zolmitriptan[no description available]medium10oxazolidinone;
tryptamines		anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
emtricitabine[no description available]medium20monothioacetal;
nucleoside analogue;
organofluorine compound;
pyrimidone		antiviral drug;
HIV-1 reverse transcriptase inhibitor
tiludronic acid[no description available]medium10organochlorine compound
tirofiban[no description available]medium10L-tyrosine derivative;
piperidines;
sulfonamide		anticoagulant;
fibrin modulating drug;
platelet glycoprotein-IIb/IIIa receptor antagonist
capecitabine[no description available]medium10carbamate ester;
cytidines;
organofluorine compound		antimetabolite;
antineoplastic agent;
prodrug
efavirenz[no description available]medium30acetylenic compound;
benzoxazine;
cyclopropanes;
organochlorine compound;
organofluorine compound		antiviral drug;
HIV-1 reverse transcriptase inhibitor
fenofibric acid[no description available]medium10aromatic ketone;
chlorobenzophenone;
monocarboxylic acid		drug metabolite;
marine xenobiotic metabolite
plerixafor[no description available]medium20azacycloalkane;
azamacrocycle;
benzenes;
crown amine;
secondary amino compound;
tertiary amino compound		anti-HIV agent;
antineoplastic agent;
C-X-C chemokine receptor type 4 antagonist;
immunological adjuvant
histamine phosphate[no description available]medium10phosphate salthistamine agonist
bendamustine[no description available]medium10benzimidazoles
repaglinide[no description available]medium10piperidines
acamprosate[no description available]medium10acetamides;
organosulfonic acid		environmental contaminant;
neurotransmitter agent;
xenobiotic
nebivolol[no description available]medium10chromanes;
diol;
organofluorine compound;
secondary alcohol;
secondary amino compound
hp 873[no description available]high101,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
doripenem[no description available]medium10carbapenems
rivastigmine[no description available]medium10carbamate ester;
tertiary amino compound		cholinergic drug;
EC 3.1.1.8 (cholinesterase) inhibitor;
neuroprotective agent
frovatriptan[no description available]medium10carbazoles
eletriptan[no description available]medium10indoles;
N-alkylpyrrolidine;
sulfone		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
bexarotene[no description available]medium10benzoic acids;
naphthalenes;
retinoid		antineoplastic agent
mci 9038[no description available]medium10peptide
perindopril[no description available]medium10alpha-amino acid ester;
dicarboxylic acid monoester;
ethyl ester;
organic heterobicyclic compound		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
tadalafil[no description available]medium10benzodioxoles;
pyrazinopyridoindole		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
paliperidone[no description available]medium101,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine;
secondary alcohol
nitisinone[no description available]medium10(trifluoromethyl)benzenes;
C-nitro compound;
cyclohexanones;
mesotrione		EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
clofarabine[no description available]medium10adenosines;
organofluorine compound		antimetabolite;
antineoplastic agent
pramipexole[no description available]medium10benzothiazoles;
diamine		antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
radical scavenger
valdecoxib[no description available]medium10isoxazoles;
sulfonamide		antipyretic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
almotriptan[no description available]medium10indoles;
sulfonamide;
tertiary amine		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
desloratadine[no description available]medium10benzocycloheptapyridineanti-allergic agent;
cholinergic antagonist;
drug metabolite;
H1-receptor antagonist
desvenlafaxine[no description available]medium10cyclohexanols;
phenols;
tertiary amino compound		antidepressant;
drug metabolite;
marine xenobiotic metabolite
rufinamide[no description available]medium10aromatic amide;
heteroarene
olmesartan medoxomil[no description available]medium10biphenyls
fosamprenavir[no description available]medium10sulfonamideprodrug
febuxostat[no description available]medium101,3-thiazolemonocarboxylic acid;
aromatic ether;
nitrile		EC 1.17.3.2 (xanthine oxidase) inhibitor
escitalopram[no description available]medium101-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrileantidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
10-propargyl-10-deazaaminopterin[no description available]medium10N-acyl-L-glutamic acid;
pteridines;
terminal acetylenic compound		antimetabolite;
antineoplastic agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
docetaxel anhydrous[no description available]medium10secondary alpha-hydroxy ketone;
tetracyclic diterpenoid		antimalarial;
antineoplastic agent;
photosensitizing agent
atazanavir[no description available]medium20carbohydrazideantiviral drug;
HIV protease inhibitor
ezetimibe[no description available]medium10azetidines;
beta-lactam;
organofluorine compound		anticholesteremic drug;
antilipemic drug;
antimetabolite
ertapenem[no description available]medium10carbapenemcarboxylic acid;
pyrrolidinecarboxamide		antibacterial drug
conivaptan[no description available]medium10benzazepineaquaretic;
vasopressin receptor antagonist
solifenacin[no description available]medium10isoquinolines
dexmethylphenidate[no description available]medium10methyl phenyl(piperidin-2-yl)acetateadrenergic agent
cinacalcet[no description available]medium10(trifluoromethyl)benzenes;
naphthalenes;
secondary amino compound		calcimimetic;
P450 inhibitor
lubiprostone[no description available]medium10
telbivudine[no description available]medium20pyrimidine 2'-deoxyribonucleosideantiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
anidulafungin[no description available]medium10antibiotic antifungal drug;
azamacrocycle;
echinocandin;
heterodetic cyclic peptide;
semisynthetic derivative
17 alpha-hydroxyprogesterone caproate[no description available]medium10corticosteroid hormone
varenicline[no description available]medium10
etravirine[no description available]medium20aminopyrimidine;
aromatic ether;
dinitrile;
organobromine compound		antiviral agent;
HIV-1 reverse transcriptase inhibitor
dronedarone[no description available]medium101-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
darunavir[no description available]medium20carbamate ester;
furofuran;
sulfonamide		antiviral drug;
HIV protease inhibitor
tbc-11251[no description available]medium10benzodioxoles
tolvaptan[no description available]medium10benzazepine;
benzenedicarboxamide		aquaretic;
vasopressin receptor antagonist
lenalidomide[no description available]medium10aromatic amine;
dicarboximide;
isoindoles;
piperidones		angiogenesis inhibitor;
antineoplastic agent;
immunomodulator
regadenoson[no description available]medium10purine nucleoside
lacosamide[no description available]medium10N-acyl-amino acid
vincaleukoblastine[no description available]medium10acetate ester;
indole alkaloid fundamental parent;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
immunosuppressive agent;
microtubule-destabilising agent;
plant metabolite
bortezomib[no description available]medium30amino acid amide;
L-phenylalanine derivative;
pyrazines		antineoplastic agent;
antiprotozoal drug;
protease inhibitor;
proteasome inhibitor
pancuronium[no description available]medium10acetate ester;
steroid ester		cholinergic antagonist;
muscle relaxant;
nicotinic antagonist
miglitol[no description available]medium10piperidines
clindamycin phosphate[no description available]medium10
eplerenone[no description available]medium103-oxo-Delta(4) steroid;
epoxy steroid;
gamma-lactone;
methyl ester;
organic heteropentacyclic compound;
oxaspiro compound;
steroid acid ester		aldosterone antagonist;
antihypertensive agent
tolterodine[no description available]medium10tertiary amineantispasmodic drug;
muscarinic antagonist;
muscle relaxant
darifenacin[no description available]medium101-benzofurans;
monocarboxylic acid amide;
pyrrolidines		antispasmodic drug;
muscarinic antagonist
clindamycin[no description available]medium10
octreotide[no description available]medium10
eptifibatide[no description available]medium10homodetic cyclic peptide;
macrocycle;
organic disulfide		anticoagulant;
platelet aggregation inhibitor
decitabine[no description available]medium102'-deoxyribonucleoside
posaconazole[no description available]medium30aromatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles		trypanocidal drug
micafungin[no description available]medium10antibiotic antifungal drug;
echinocandin		antiinfective agent
riboflavin[no description available]medium30flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
sr 90107[no description available]medium10
meglumine iodipamide[no description available]medium10organoammonium saltradioopaque medium
thyrotropin-releasing hormone[no description available]medium10peptide hormone;
tripeptide		human metabolite
arginine vasopressin[no description available]medium140vasopressincardiovascular drug;
hematologic agent;
mitogen
s 1033[no description available]medium10(trifluoromethyl)benzenes;
imidazoles;
pyridines;
pyrimidines;
secondary amino compound;
secondary carboxamide		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
pyrantel[no description available]medium101,4,5,6-tetrahydropyrimidines;
carboxamidine;
thiophenes		antinematodal drug
eszopiclone[no description available]medium10zopiclonecentral nervous system depressant;
sedative
cancidas[no description available]medium10
lincomycin[no description available]medium10carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite
nelarabine[no description available]medium10beta-D-arabinoside;
monosaccharide derivative;
purine nucleoside		antineoplastic agent;
DNA synthesis inhibitor;
prodrug
dermatan sulfate[no description available]medium10amino disaccharide;
glycosylgalactose derivative;
iduronic acids;
oligosaccharide sulfate
dolasetron[no description available]medium10indolyl carboxylic acid
fospropofol[no description available]medium10alkylbenzene
rasagiline[no description available]medium10indanes;
secondary amine;
terminal acetylenic compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
neuroprotective agent
mivacurium[no description available]medium10isoquinolines
hemabate[no description available]medium10
mycophenolate mofetil[no description available]medium20carboxylic ester;
ether;
gamma-lactone;
phenols;
tertiary amino compound		anticoronaviral agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
immunosuppressive agent;
prodrug
paricalcitol[no description available]medium10hydroxy seco-steroid;
seco-cholestane		antiparathyroid drug
indocyanine green[no description available]medium101,1-diunsubstituted alkanesulfonate;
benzoindole;
cyanine dye
ethamolin[no description available]medium10long-chain fatty acid
alatrofloxacin mesylate[no description available]medium10
estropipate[no description available]medium10piperazinium salt;
steroid sulfate
nabilone[no description available]medium10
vitamin k 1[no description available]medium10phylloquinones;
vitamin K		cofactor;
human metabolite;
plant metabolite
trospium chloride[no description available]medium10
deamino arginine vasopressin[no description available]medium20heterodetic cyclic peptidediagnostic agent;
renal agent;
vasopressin receptor agonist
dexmedetomidine[no description available]medium10medetomidinealpha-adrenergic agonist;
analgesic;
non-narcotic analgesic;
sedative
goserelin[no description available]medium20organic molecular entity
nateglinide[no description available]medium10phenylalanine derivative
silodosin[no description available]medium10indolecarboxamide
verteporfin[no description available]medium20
n-methylscopolamine bromide[no description available]medium10
bleomycin[no description available]medium10bleomycinantineoplastic agent;
metabolite
pregabalin[no description available]medium10gamma-amino acidanticonvulsant;
calcium channel blocker
alvimopan anhydrous[no description available]medium10peptide
aliskiren[no description available]medium10monocarboxylic acid amide;
monomethoxybenzene		antihypertensive agent
palonosetron[no description available]medium10azabicycloalkane;
delta-lactam;
organic heterotricyclic compound		antiemetic;
serotonergic antagonist
rifaximin[no description available]medium10acetate ester;
cyclic ketal;
lactam;
macrocycle;
organic heterohexacyclic compound;
rifamycins;
semisynthetic derivative		antimicrobial agent;
gastrointestinal drug;
orphan drug
everolimus[no description available]medium10cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
primary alcohol;
secondary alcohol		anticoronaviral agent;
antineoplastic agent;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
ixabepilone[no description available]medium101,3-thiazoles;
beta-hydroxy ketone;
epoxide;
lactam;
macrocycle		antineoplastic agent;
microtubule-destabilising agent
cefdinir[no description available]medium10cephalosporin;
ketoxime		antibacterial drug
etonogestrel[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound		contraceptive drug;
female contraceptive drug;
progestin
temsirolimus[no description available]medium10macrolide lactam
dutasteride[no description available]medium10(trifluoromethyl)benzenes;
aza-steroid;
delta-lactam		antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
fesoterodine[no description available]medium10diarylmethane
dexlansoprazole[no description available]medium10benzimidazoles;
sulfoxide
armodafinil[no description available]medium102-[(diphenylmethyl)sulfinyl]acetamidecentral nervous system stimulant;
eugeroic
sincalide[no description available]medium60oligopeptide
tapentadol[no description available]medium10alkylbenzene
pentagastrin[no description available]medium10organic molecular entity
cefditoren[no description available]medium10carboxylic acid;
cephalosporin		antibacterial drug
prasugrel hydrochloride[no description available]medium10
bms 477118[no description available]medium20adamantanes;
azabicycloalkane;
monocarboxylic acid amide;
nitrile;
tertiary alcohol		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent
milnacipran[no description available]medium10acetamides
bivalirudin[no description available]medium10polypeptideanticoagulant;
EC 3.4.21.5 (thrombin) inhibitor
enfuvirtide[no description available]medium10
ganirelix[no description available]medium10polypeptide
teriparatide[no description available]medium10polypeptide
salmon calcitonin[no description available]medium10heterodetic cyclic peptide;
peptide hormone;
polypeptide		bone density conservation agent;
metabolite
ly-146032[no description available]medium10heterodetic cyclic peptide;
lipopeptide antibiotic;
lipopeptide;
macrocycle;
macrolide		antibacterial drug;
bacterial metabolite;
calcium-dependent antibiotics
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide[no description available]medium10polypeptide
exenatide[no description available]medium10
sodium lactate[no description available]medium10lactate salt;
organic sodium salt		food acidity regulator;
food preservative
sodium iothalamate[no description available]medium10
cetrorelix[no description available]medium10oligopeptideantineoplastic agent;
GnRH antagonist
raltegravir[no description available]medium101,2,4-oxadiazole;
dicarboxylic acid amide;
hydroxypyrimidine;
monofluorobenzenes;
pyrimidone;
secondary carboxamide		antiviral drug;
HIV-1 integrase inhibitor
tigecycline[no description available]medium10
fertinex[no description available]medium10
entecavir[no description available]medium202-aminopurines;
oxopurine;
primary alcohol;
secondary alcohol		antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
vardenafil[no description available]medium10imidazotriazine;
N-alkylpiperazine;
N-sulfonylpiperazine		EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
rifapentine[no description available]medium10N-alkylpiperazine;
N-iminopiperazine;
rifamycins		antitubercular agent;
leprostatic drug
bl 4162a[no description available]medium10imidazoquinazolineanticoagulant;
antifibrinolytic drug;
cardiovascular drug;
platelet aggregation inhibitor
tegaserod[no description available]medium20carboxamidine;
guanidines;
hydrazines;
indoles		gastrointestinal drug;
serotonergic agonist
pemetrexed[no description available]medium20N-acyl-L-glutamic acid;
pyrrolopyrimidine		antimetabolite;
antineoplastic agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
EC 2.1.1.45 (thymidylate synthase) inhibitor;
EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
valganciclovir[no description available]medium10L-valyl ester;
purines		antiviral drug;
prodrug
aprepitant[no description available]medium20(trifluoromethyl)benzenes;
cyclic acetal;
morpholines;
triazoles		antidepressant;
antiemetic;
neurokinin-1 receptor antagonist;
peripheral nervous system drug;
substance P receptor antagonist
fosaprepitant[no description available]medium10(trifluoromethyl)benzenes;
cyclic acetal;
morpholines;
phosphoramide;
triazoles		antiemetic;
neurokinin-1 receptor antagonist;
prodrug
levomefolate calcium[no description available]medium10organic calcium saltantidepressant
w 7[no description available]medium2640
lubeluzole[no description available]medium10benzothiazoles
aurintricarboxylic acid[no description available]medium10monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist
candesartan cilexetil[no description available]medium20biphenyls
gw 7647[no description available]medium10aryl sulfide;
monocarboxylic acid;
ureas		PPARalpha agonist
rottlerin[no description available]medium10aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
ellagic acid[no description available]medium10catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent
manoalide[no description available]medium10butenolide;
lactol;
sesterterpenoid		EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
metabolite
3-o-methylfunicone[no description available]medium10
purfalcamine[no description available]medium10
4,5,6,7-tetrabromobenzimidazole[no description available]medium10
cct 128930[no description available]medium10
gdc 0941[no description available]medium10indazoles;
morpholines;
piperazines;
sulfonamide;
thienopyrimidine		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
cetylpyridinium chloride anhydrous[no description available]medium20chloride salt;
organic chloride salt		antiseptic drug;
surfactant
pevonedistat[no description available]medium20cyclopentanols;
indanes;
pyrrolopyrimidine;
secondary amino compound;
sulfamidate		antineoplastic agent;
apoptosis inducer
2-aminoethoxydiphenyl borate[no description available]medium20organoboron compound;
primary amino compound		calcium channel blocker;
IP3 receptor antagonist;
potassium channel opener
chlorocresol[no description available]medium10hydroxytoluene;
monochlorobenzenes		antimicrobial agent;
disinfectant;
ryanodine receptor agonist
4-nonylphenol[no description available]medium10phenolsenvironmental contaminant
2,5-di-tert-butylhydroquinone[no description available]medium10hydroquinones
cgp 37157[no description available]medium20benzothiazepine
chelerythrine[no description available]medium40benzophenanthridine alkaloid;
organic cation		antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
tetrabromobisphenol a[no description available]medium10brominated flame retardant;
bromobisphenol
bisphenol a[no description available]medium10bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
epigallocatechin gallate[no description available]medium20flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite
saikosaponin d[no description available]medium10
3,6-dihydroxyflavone[no description available]medium10
curcumin[no description available]medium20aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
22,23-dihydroavermectin b(1)a[no description available]medium10macrocyclic lactone;
spiroketal
alisol b[no description available]medium10triterpenoid
ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4h-chromene-3-carboxylate[no description available]medium10
biselyngbyaside[no description available]medium10
aminolevulinic acid[no description available]medium204-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid		antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
thioctic acid[no description available]medium10dithiolanes;
heterocyclic fatty acid;
thia fatty acid		fundamental metabolite;
geroprotector
picolinic acid[no description available]medium10pyridinemonocarboxylic acidhuman metabolite;
MALDI matrix material
3-aminobenzamide[no description available]medium10benzamides;
substituted aniline		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
pleconaril[no description available]medium10
4-(2-aminoethyl)benzenesulfonylfluoride[no description available]medium10
alprenolol[no description available]medium10secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
2-aminothiazole[no description available]medium101,3-thiazoles;
primary amino compound
camostat[no description available]medium10benzoate ester;
carboxylic ester;
diester;
guanidines;
tertiary carboxamide		anti-inflammatory agent;
anticoronaviral agent;
antifibrinolytic drug;
antihypertensive agent;
antineoplastic agent;
antiviral agent;
serine protease inhibitor
camphor, (+-)-isomer[no description available]medium10bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
cetylpyridinium[no description available]medium10pyridinium ion
deferiprone[no description available]medium104-pyridonesiron chelator;
protective agent
2-hexyloxybenzamide[no description available]medium10aromatic ether;
benzamides		antifungal agent
gabexate[no description available]medium20benzoate ester
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
fasudil[no description available]medium10isoquinolines;
N-sulfonyldiazepane		antihypertensive agent;
calcium channel blocker;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
geroprotector;
neuroprotective agent;
nootropic agent;
vasodilator agent
miltefosine[no description available]medium10phosphocholines;
phospholipid		anti-inflammatory agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antiprotozoal drug;
apoptosis inducer;
immunomodulator;
protein kinase inhibitor
hexylresorcinol[no description available]medium10resorcinols
beta-thujaplicin[no description available]medium10cyclic ketone;
enol;
monoterpenoid		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiplasmodial drug;
plant metabolite
kojic acid[no description available]medium104-pyranones;
enol;
primary alcohol		Aspergillus metabolite;
EC 1.10.3.1 (catechol oxidase) inhibitor;
EC 1.10.3.2 (laccase) inhibitor;
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 1.4.3.3 (D-amino-acid oxidase) inhibitor;
NF-kappaB inhibitor;
skin lightening agent
lapachol[no description available]medium10
4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide[no description available]medium10benzamides;
hydroxamic acid;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor
mafenide[no description available]medium10aromatic amine
entinostat[no description available]medium10benzamides;
carbamate ester;
primary amino compound;
pyridines;
substituted aniline		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor
ethylmaleimide[no description available]medium110maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
nafamostat[no description available]medium10benzoic acids;
guanidines
osalmide[no description available]medium10organic molecular entity
palmidrol[no description available]medium10endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent
phenazopyridine[no description available]medium10diaminopyridine;
monoazo compound		anticoronaviral agent;
carcinogenic agent;
local anaesthetic;
non-narcotic analgesic
phenylmethylsulfonyl fluoride[no description available]medium10acyl fluorideserine proteinase inhibitor
pimobendan[no description available]medium20benzimidazoles;
pyridazinone		cardiotonic drug;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
pj-34[no description available]medium10phenanthridines;
secondary carboxamide;
tertiary amino compound		angiogenesis inhibitor;
anti-inflammatory agent;
antiatherosclerotic agent;
antineoplastic agent;
apoptosis inducer;
cardioprotective agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
neuroprotective agent
scriptaid[no description available]medium10isoquinolines
sebacic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite;
plant metabolite
fenofibrate[no description available]medium10benzochromenone;
delta-lactone;
naphtho-alpha-pyrone		platelet aggregation inhibitor;
Sir2 inhibitor
trigonelline[no description available]medium10alkaloid;
iminium betaine		food component;
human urinary metabolite;
plant metabolite
tyrphostin a9[no description available]medium10alkylbenzenegeroprotector
vesnarinone[no description available]medium10organic molecular entity
lysine[no description available]medium50aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenylethyl alcohol[no description available]medium10benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite
ficusin[no description available]medium10psoralensplant metabolite
tubercidin[no description available]medium20antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
ribonucleoside		antimetabolite;
antineoplastic agent;
bacterial metabolite
salicylanilide[no description available]medium10benzanilide fungicide;
salicylamides;
salicylanilides
gramine[no description available]medium10aminoalkylindole;
indole alkaloid;
tertiary amino compound		antibacterial agent;
antiviral agent;
plant metabolite;
serotonergic antagonist
aminacrine[no description available]medium40aminoacridines;
primary amino compound		acid-base indicator;
antiinfective agent;
antiseptic drug;
fluorescent dye;
MALDI matrix material;
mutagen
methyl gallate[no description available]medium10gallate esteranti-inflammatory agent;
antioxidant;
plant metabolite
monobenzone[no description available]medium10benzyl etherallergen;
dermatologic drug;
melanin synthesis inhibitor
lucanthone[no description available]medium20thioxanthenesadjuvant;
antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
mutagen;
photosensitizing agent;
prodrug;
schistosomicide drug
cepharanthine[no description available]medium20bisbenzylisoquinoline alkaloid;
isoquinolines
aloe emodin[no description available]medium10aromatic primary alcohol;
dihydroxyanthraquinone		antineoplastic agent;
plant metabolite
osthol[no description available]medium10botanical anti-fungal agent;
coumarins		metabolite
flavanone[no description available]medium10flavanones
phloretic acid[no description available]medium10hydroxy monocarboxylic acidplant metabolite
oleanolic acid[no description available]medium10hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
angelicin[no description available]medium10furanocoumarin
hydroxychloroquine sulfate[no description available]medium10
metformin hydrochloride[no description available]medium10hydrochlorideenvironmental contaminant;
hypoglycemic agent;
xenobiotic
antimycin a[no description available]medium10benzamides;
formamides;
macrodiolide;
phenols		antifungal agent;
mitochondrial respiratory-chain inhibitor;
piscicide
5,5'-dimethyl-2,2'-bipyridyl[no description available]medium10bipyridines
dichlorobenzyl alcohol[no description available]medium10benzyl alcohols;
dichlorobenzene		antiseptic drug
dideoxyadenosine[no description available]medium10adenosines;
purine 2',3'-dideoxyribonucleoside		EC 3.5.4.4 (adenosine deaminase) inhibitor;
EC 4.6.1.1 (adenylate cyclase) inhibitor
3-deazaadenosine[no description available]medium20
ancitabine[no description available]medium10diol;
organic heterotricyclic compound		antimetabolite;
antineoplastic agent;
prodrug
chloropyramine[no description available]medium10aminopyridine
n'-nitrosonornicotine[no description available]medium10pyridines;
pyrrolidines
pyridoxal phosphate[no description available]medium10pyridinecarbaldehyde
oltipraz[no description available]medium101,2-dithiole;
pyrazines		angiogenesis modulating agent;
antimutagen;
antineoplastic agent;
antioxidant;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
neurotoxin;
protective agent;
schistosomicide drug
fiacitabine[no description available]medium10
brequinar[no description available]medium10biphenyls;
monocarboxylic acid;
monofluorobenzenes;
quinolinemonocarboxylic acid		anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor;
immunosuppressive agent;
pyrimidine synthesis inhibitor
imiquimod[no description available]medium10imidazoquinolineantineoplastic agent;
interferon inducer
celgosivir[no description available]medium10
zanamivir[no description available]medium10guanidinesantiviral agent;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
adefovir dipivoxil[no description available]medium106-aminopurines;
carbonate ester;
ether;
organic phosphonate		antiviral drug;
DNA synthesis inhibitor;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent;
prodrug
betulinic acid[no description available]medium10hydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-HIV agent;
anti-inflammatory agent;
antimalarial;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
plant metabolite
arctigenin[no description available]medium10lignan
baicalin[no description available]medium10dihydroxyflavone;
glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative		antiatherosclerotic agent;
antibacterial agent;
anticoronaviral agent;
antineoplastic agent;
antioxidant;
cardioprotective agent;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
ferroptosis inhibitor;
neuroprotective agent;
non-steroidal anti-inflammatory drug;
plant metabolite;
prodrug
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose[no description available]medium10gallate ester;
galloyl beta-D-glucose		anti-inflammatory agent;
antineoplastic agent;
geroprotector;
hepatoprotective agent;
plant metabolite;
radiation protective agent;
radical scavenger
cephalotaxine[no description available]medium10benzazepine alkaloid fundamental parent;
benzazepine alkaloid;
cyclic acetal;
enol ether;
organic heteropentacyclic compound;
secondary alcohol;
tertiary amino compound
desipramine hydrochloride[no description available]medium10hydrochloridedrug allergen
mefloquine hydrochloride[no description available]medium10hydrochloride
propazole[no description available]medium10benzimidazoles
prulifloxacin[no description available]medium10fluoroquinolone antibiotic;
quinolone antibiotic
bergenin[no description available]medium10trihydroxybenzoic acidmetabolite
brinzolamide[no description available]medium10sulfonamide;
thienothiazine		antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
dipropylacetamide[no description available]medium10fatty amidegeroprotector;
metabolite;
teratogenic agent
oxprenolol hydrochloride[no description available]medium10
opipramol hydrochloride[no description available]medium10
moroxydine[no description available]medium10biguanides
thioxolone[no description available]medium10benzoxathioleantiseborrheic
honokiol[no description available]medium20biphenyls
nobiletin[no description available]medium10methoxyflavoneantineoplastic agent;
plant metabolite
lycorine[no description available]medium10indolizidine alkaloidanticoronaviral agent;
antimalarial;
plant metabolite;
protein synthesis inhibitor
leupeptin[no description available]medium40aldehyde;
tripeptide		bacterial metabolite;
calpain inhibitor;
cathepsin B inhibitor;
EC 3.4.21.4 (trypsin) inhibitor;
serine protease inhibitor
tetrandrine[no description available]medium10bisbenzylisoquinoline alkaloid;
isoquinolines
fangchinoline[no description available]medium10aromatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle		anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite
maslinic acid[no description available]medium10dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
plant metabolite
loganin[no description available]medium10beta-D-glucoside;
cyclopentapyran;
enoate ester;
iridoid monoterpenoid;
methyl ester;
monosaccharide derivative;
secondary alcohol		anti-inflammatory agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
EC 3.4.23.46 (memapsin 2) inhibitor;
neuroprotective agent;
plant metabolite
aucubin[no description available]medium10organic molecular entitymetabolite
catalpol[no description available]medium10organic molecular entitymetabolite
n-methyladenosine[no description available]medium10methyladenosine
geniposide[no description available]medium10terpene glycoside
daidzin[no description available]medium107-hydroxyisoflavones 7-O-beta-D-glucoside;
hydroxyisoflavone;
monosaccharide derivative		plant metabolite
sophocarpine[no description available]medium10
marimastat[no description available]medium10hydroxamic acid;
secondary carboxamide		antineoplastic agent;
matrix metalloproteinase inhibitor
elacridar[no description available]medium10
celastrol[no description available]medium10monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory drug;
antineoplastic agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Hsp90 inhibitor;
metabolite
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine[no description available]medium10leucine derivative
vadimezan[no description available]medium10monocarboxylic acid;
xanthones		antineoplastic agent
e 64[no description available]medium20dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor
umifenovir[no description available]medium10indolyl carboxylic acid
safinamide[no description available]medium10amino acid amide
vx 497[no description available]medium10
bcx 1812[no description available]medium103-hydroxy monocarboxylic acid;
acetamides;
cyclopentanols;
guanidines		antiviral drug;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
celastrol methyl ester[no description available]medium10carboxylic ester
resiquimod[no description available]medium10imidazoquinoline
anacardic acid[no description available]medium10hydroxy monocarboxylic acid;
hydroxybenzoic acid		anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
apoptosis inducer;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
neuroprotective agent;
plant metabolite
migalastat[no description available]medium10piperidines
limonin[no description available]medium10epoxide;
furans;
hexacyclic triterpenoid;
lactone;
limonoid;
organic heterohexacyclic compound		inhibitor;
metabolite;
volatile oil component
scutellarin[no description available]medium10glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		antineoplastic agent;
proteasome inhibitor
chelidonine[no description available]medium10alkaloid antibiotic;
alkaloid fundamental parent;
benzophenanthridine alkaloid
4-n-butylresorcinol[no description available]medium10resorcinols
dapivirine[no description available]medium10
nsc 74859[no description available]medium10amidobenzoic acid;
monohydroxybenzoic acid;
tosylate ester		STAT3 inhibitor
berbamine[no description available]medium10bisbenzylisoquinoline alkaloid;
isoquinolines
u-104[no description available]medium10
7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]-1-benzopyran-4-one[no description available]medium10glycoside
tizoxanide[no description available]medium10salicylamides
arbutin[no description available]medium10beta-D-glucoside;
monosaccharide derivative		Escherichia coli metabolite;
plant metabolite
conessine[no description available]medium10steroid alkaloid;
tertiary amino compound		antibacterial agent;
antimalarial;
H3-receptor antagonist;
plant metabolite
cephaelin[no description available]medium10pyridoisoquinoline
(-)-usnic acid[no description available]medium10usnic acidEC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
lycopene[no description available]medium10acyclic caroteneantioxidant;
plant metabolite
roflumilast[no description available]medium10aromatic ether;
benzamides;
chloropyridine;
cyclopropanes;
organofluorine compound		anti-asthmatic drug;
phosphodiesterase IV inhibitor
L-cycloserine[no description available]medium104-amino-1,2-oxazolidin-3-oneanti-HIV agent;
anticonvulsant;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
h 89[no description available]medium30N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
bevirimat[no description available]medium10dicarboxylic acid monoester;
monocarboxylic acid;
pentacyclic triterpenoid		HIV-1 maturation inhibitor;
metabolite
benzyloxycarbonylleucyl-leucyl-leucine aldehyde[no description available]medium40amino aldehyde;
carbamate ester;
tripeptide		proteasome inhibitor
gw 257406x[no description available]medium10
shikonin[no description available]medium10hydroxy-1,4-naphthoquinone
4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide[no description available]medium10tropane alkaloid
cmx 001[no description available]medium10
amd 8664[no description available]medium10
bay 41-4109[no description available]medium10
bay 57-1293[no description available]medium10
2'-c-methylcytidine[no description available]medium10
isoxanthohumol[no description available]medium10flavanones
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide[no description available]medium10aromatic ether
mecarbinate[no description available]medium10
acetyl-aspartyl-glutamyl-valyl-aspartal[no description available]medium10tetrapeptideprotease inhibitor
jrf 12[no description available]medium10
3,4'-dihydroxyflavone[no description available]medium10
3-(3,4-dimethoxyphenyl)propenoic acid[no description available]medium10methoxycinnamic acid
isoferulic acid[no description available]medium10ferulic acidsantioxidant;
biomarker;
metabolite
cyclouridine[no description available]medium10
zucapsaicin[no description available]medium10methoxybenzenes;
phenols
nbd 556[no description available]medium10
4,5,6,7-tetrachloroindan-1,3-dione[no description available]medium10
srpin340[no description available]medium10
pr-619[no description available]medium10
p5091[no description available]medium10
trovirdine[no description available]medium10
fti 277[no description available]medium10
u 0126[no description available]medium10aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
vicriviroc[no description available]medium10(trifluoromethyl)benzenes
telaprevir[no description available]medium10cyclopentapyrrole;
cyclopropanes;
oligopeptide;
pyrazines		antiviral drug;
hepatitis C protease inhibitor;
peptidomimetic
yya-021[no description available]medium10
sb 415286[no description available]medium10C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
tak-220[no description available]medium10
jtk-303[no description available]medium10aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		HIV-1 integrase inhibitor
nbd 557[no description available]medium10
5'-o-caffeoylquinic acid[no description available]medium10cinnamate ester;
cyclitol carboxylic acid		plant metabolite
luteolin-7-glucoside[no description available]medium10beta-D-glucoside;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		antioxidant;
plant metabolite
cyclosporine[no description available]medium10
amentoflavone[no description available]medium10biflavonoid;
hydroxyflavone;
ring assembly		angiogenesis inhibitor;
antiviral agent;
cathepsin B inhibitor;
P450 inhibitor;
plant metabolite
genkwanin[no description available]medium10dihydroxyflavone;
monomethoxyflavone		metabolite
hyperoside[no description available]medium10beta-D-galactoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite
mangostin[no description available]medium10aromatic ether;
phenols;
xanthones		antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite
3-methylquercetin[no description available]medium107-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite
kaempferide[no description available]medium107-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite
orientin[no description available]medium103'-hydroxyflavonoid;
C-glycosyl compound;
tetrahydroxyflavone		antioxidant;
metabolite
scutellarein[no description available]medium10tetrahydroxyflavonemetabolite
trans-2,3',4,5'-tetrahydroxystilbene[no description available]medium10stilbenoid
chicoric acid[no description available]medium10organooxygen compoundgeroprotector;
HIV-1 integrase inhibitor
acteoside[no description available]medium10catechols;
cinnamate ester;
disaccharide derivative;
glycoside;
polyphenol		anti-inflammatory agent;
antibacterial agent;
antileishmanial agent;
neuroprotective agent;
plant metabolite
benzyloxycarbonyl-phe-ala-fluormethylketone[no description available]medium10
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester[no description available]medium10carboxylic ester;
difluorobenzene;
dipeptide;
tert-butyl ester		EC 3.4.23.46 (memapsin 2) inhibitor
casticin[no description available]medium10dihydroxyflavone;
tetramethoxyflavone		apoptosis inducer;
plant metabolite
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one[no description available]medium10dihydroxyflavone;
monomethoxyflavone		antineoplastic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside[no description available]medium10beta-D-glucoside;
resorcinols;
stilbenoid		anti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
cyclooxygenase 2 inhibitor;
platelet aggregation inhibitor
tyrphostin ag 555[no description available]medium10
pd 151746[no description available]medium10
batimastat[no description available]medium10hydroxamic acid;
L-phenylalanine derivative;
organic sulfide;
secondary carboxamide;
thiophenes;
triamide		angiogenesis inhibitor;
antineoplastic agent;
matrix metalloproteinase inhibitor
solanesol[no description available]medium10nonaprenol;
primary alcohol		plant metabolite
pepstatin[no description available]medium10pentapeptide;
secondary carboxamide		bacterial metabolite;
EC 3.4.23.* (aspartic endopeptidase) inhibitor
l 685458[no description available]medium10carbamate ester;
monocarboxylic acid amide;
peptide;
secondary alcohol		EC 3.4.23.46 (memapsin 2) inhibitor;
peptidomimetic
bms 806[no description available]medium10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone[no description available]medium10
tulobuterol hydrochloride[no description available]medium10organic molecular entity
salubrinal[no description available]medium10aminal;
organochlorine compound;
quinolines;
secondary carboxamide;
thioureas
germacrone[no description available]medium10germacrane sesquiterpenoid;
olefinic compound		androgen antagonist;
anti-inflammatory agent;
antifeedant;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antioxidant;
antitussive;
antiviral agent;
apoptosis inducer;
autophagy inducer;
hepatoprotective agent;
insecticide;
neuroprotective agent;
plant metabolite;
volatile oil component
(2e,4e,6e,10e)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid[no description available]medium10
lithospermic acid[no description available]medium10
laq824[no description available]medium10
ekb 569[no description available]medium10aminoquinoline;
monocarboxylic acid amide;
monochlorobenzenes;
nitrile		protein kinase inhibitor
rilpivirine[no description available]medium10aminopyrimidine;
nitrile		EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor
(1Ar,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one[no description available]medium10germacranolide
4,5-di-O-caffeoylquinic acid[no description available]medium10quinic acid
indigo carmine[no description available]medium10
(3S,6S,9S,12R)-3-[(2S)-Butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone[no description available]medium10oligopeptide
vildagliptin[no description available]medium10amino acid amide
belinostat[no description available]medium10hydroxamic acid;
olefinic compound;
sulfonamide		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor
hdac-42[no description available]medium10amidobenzoic acid
gs-7340[no description available]medium106-aminopurines;
ether;
isopropyl ester;
L-alanine derivative;
phosphoramidate ester		antiviral drug;
HIV-1 reverse transcriptase inhibitor;
prodrug
iniparib[no description available]medium10carbonyl compound;
organohalogen compound
n-(2-amino-5-fluorobenzyl)-4-(n-(pyridine-3-acrylyl)aminomethyl)benzamide[no description available]medium10
pri-2205[no description available]medium10
mk 0752[no description available]medium10
givinostat[no description available]medium10carbamate ester
pd 144418[no description available]medium10
bicyclol[no description available]medium10
midostaurin[no description available]medium10benzamides;
gamma-lactam;
indolocarbazole;
organic heterooctacyclic compound		antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
mocetinostat[no description available]medium30aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
rivaroxaban[no description available]medium10aromatic amide;
lactam;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
oxazolidinone;
thiophenes		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
sb 3ct compound[no description available]medium10aromatic ether
ginsenoside rb1[no description available]medium10ginsenoside;
glycoside;
tetracyclic triterpenoid		anti-inflammatory drug;
anti-obesity agent;
apoptosis inhibitor;
neuroprotective agent;
plant metabolite;
radical scavenger
rucaparib[no description available]medium10azepinoindole;
caprolactams;
organofluorine compound;
secondary amino compound		antineoplastic agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-n-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6s)-[no description available]medium10organonitrogen heterocyclic compound;
organosulfur heterocyclic compound
cetilistat[no description available]medium10benzoxazine
ym 201636[no description available]medium10aromatic amide
linagliptin[no description available]medium10aminopiperidine;
quinazolines		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent
azd 6244[no description available]medium10benzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monochlorobenzenes;
organofluorine compound;
secondary amino compound		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
odanacatib[no description available]medium10
apilimod[no description available]medium10
apixaban[no description available]medium10aromatic ether;
lactam;
piperidones;
pyrazolopyridine		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
betrixaban[no description available]medium10benzamides;
guanidines;
monochloropyridine;
monomethoxybenzene;
secondary carboxamide		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
edoxaban[no description available]medium10chloropyridine;
monocarboxylic acid amide;
tertiary amino compound;
thiazolopyridine		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor;
platelet aggregation inhibitor
saracatinib[no description available]medium10aromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound		anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent
n-(3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl)-3-(2-((((1,1-dimethylethyl)amino)carbonyl)amino)-3,3-dimethyl-1-oxobutyl)-6,6-dimethyl-3-azabicyclo(3.1.0)hexan-2-carboxamide[no description available]medium10tripeptide;
ureas		antiviral drug;
hepatitis C protease inhibitor;
peptidomimetic
ly 411575[no description available]medium10dibenzoazepine;
difluorobenzene;
lactam;
secondary alcohol		EC 3.4.23.46 (memapsin 2) inhibitor
galidesivir[no description available]medium10
PB28[no description available]medium10aromatic ether;
piperazines;
tetralins		anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist
degrasyn[no description available]medium10
epoxomicin[no description available]medium10morpholines;
tripeptide		proteasome inhibitor
pha 680632[no description available]medium10
tmc 353121[no description available]medium10
amd 070[no description available]medium10aminoquinoline
danoprevir[no description available]medium10
bms-626529[no description available]medium10
bms-663068[no description available]medium10
amenamevir[no description available]medium10
vx 765[no description available]medium10dipeptide
Dihydrotanshinone I[no description available]medium10abietane diterpenoidanticoronaviral agent
alogliptin[no description available]medium10nitrile;
piperidines;
primary amino compound;
pyrimidines		EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent
fr 180204[no description available]medium10pyrazoles;
ring assembly
quisinostat[no description available]medium10indoles
carfilzomib[no description available]medium10epoxide;
morpholines;
tetrapeptide		antineoplastic agent;
proteasome inhibitor
hcv 796[no description available]medium10
resminostat[no description available]medium10
zk 756326[no description available]medium10aromatic ether
balapiravir[no description available]medium10
trametinib[no description available]medium10acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
deoxyarbutin[no description available]medium10
abexinostat[no description available]medium10benzofurans
silvestrol[no description available]medium10dioxanes;
ether;
methyl ester;
organic heterotricyclic compound		antineoplastic agent;
metabolite
narlaprevir[no description available]medium10azabicyclohexane;
cyclopropanes;
pyrrolidinecarboxamide;
secondary carboxamide;
sulfone;
tertiary carboxamide;
ureas		anticoronaviral agent;
antiviral drug;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
hepatitis C protease inhibitor
teneligliptin[no description available]medium10amino acid amide
dextrothyroxine[no description available]medium20
veliparib[no description available]medium10benzimidazolesEC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
pf 03491390[no description available]medium10
alloin[no description available]medium10anthracenes;
C-glycosyl compound;
cyclic ketone;
phenols		laxative;
metabolite
mdv 3100[no description available]medium10(trifluoromethyl)benzenes;
benzamides;
imidazolidinone;
monofluorobenzenes;
nitrile;
thiocarbonyl compound		androgen antagonist;
antineoplastic agent
bms-650032[no description available]medium10oligopeptide
rg 7128[no description available]medium10
oritavancin[no description available]medium10disaccharide derivative;
glycopeptide;
semisynthetic derivative		antibacterial drug;
antimicrobial agent
uk 453,061[no description available]medium10aromatic ether
N-(2-aminophenyl)-2-pyrazinecarboxamide[no description available]medium10aromatic amide
tegobuvir[no description available]medium10
pf-429242[no description available]medium10
olaparib[no description available]medium10cyclopropanes;
monofluorobenzenes;
N-acylpiperazine;
phthalazines		antineoplastic agent;
apoptosis inducer;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
cx 4945[no description available]medium10
pci 34051[no description available]medium10indolecarboxamide
lomibuvir[no description available]medium10thiophenecarboxylic acid
delanzomib[no description available]medium10C-terminal boronic acid peptide;
phenylpyridine;
secondary alcohol;
threonine derivative		antineoplastic agent;
apoptosis inducer;
proteasome inhibitor
pitavastatin(1-)[no description available]medium10hydroxy monocarboxylic acid anion
GRL-0617[no description available]medium10benzamides;
naphthalenes;
secondary carboxamide;
substituted aniline		anticoronaviral agent;
protease inhibitor
N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]-oxomethyl]-5-isoxazolyl]phenyl]carbamic acid tert-butyl ester[no description available]medium10carbamate ester
niraparib[no description available]medium102-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamideantineoplastic agent;
apoptosis inducer;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
radiosensitizing agent
jzl 184[no description available]medium10benzodioxoles
gsk 650394[no description available]medium10phenylpyridine
oprozomib[no description available]medium10
az 960[no description available]medium10
golgicide a[no description available]medium10diastereoisomeric mixturecis-Golgi ArfGEF GBF inhibitor
cobicistat[no description available]medium101,3-thiazoles;
carbamate ester;
monocarboxylic acid amide;
morpholines;
ureas		P450 inhibitor
bms-790052[no description available]medium10biphenyls;
carbamate ester;
carboxamide;
imidazoles;
valine derivative		antiviral drug;
nonstructural protein 5A inhibitor
ixazomib[no description available]medium10benzamides;
boronic acids;
dichlorobenzene;
glycine derivative		antineoplastic agent;
apoptosis inducer;
drug metabolite;
orphan drug;
proteasome inhibitor
ucph 101[no description available]medium10
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine[no description available]medium10aryl sulfide;
thienopyrimidine
baricitinib[no description available]medium10azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide		anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent
KOM70144[no description available]medium10acetamides;
benzamides;
naphthalenes;
secondary carboxamide		anticoronaviral agent;
protease inhibitor
e-52862[no description available]medium10
ly2811376[no description available]medium10
anagliptin[no description available]medium10amino acid amide
gardiquimod[no description available]medium10
grazoprevir[no description available]medium10aromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative		antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent
abt-450[no description available]medium10
letermovir[no description available]medium10
sofosbuvir[no description available]medium10isopropyl ester;
L-alanyl ester;
nucleotide conjugate;
organofluorine compound;
phosphoramidate ester		antiviral drug;
hepatitis C protease inhibitor;
prodrug
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine[no description available]medium10benzoxazole
blz 945[no description available]medium10
azd3839[no description available]medium10
pf 3084014[no description available]medium10
unc 0638[no description available]medium10quinazolines
gs-9620[no description available]medium10
n-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1h-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide[no description available]medium10
bms 708163[no description available]medium10oxadiazole;
ring assembly
jq1 compound[no description available]medium10carboxylic ester;
organochlorine compound;
tert-butyl ester;
thienotriazolodiazepine		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
bromodomain-containing protein 4 inhibitor;
cardioprotective agent;
ferroptosis inducer
1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone[no description available]medium10
gsk525762a[no description available]medium10benzodiazepine
ML240[no description available]medium10aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound		antineoplastic agent
birinapant[no description available]medium10dipeptide
ly2886721[no description available]medium10
nms-p118[no description available]medium10
tubastatin a[no description available]medium10hydroxamic acid;
pyridoindole;
tertiary amino compound		EC 3.5.1.98 (histone deacetylase) inhibitor
pracinostat[no description available]medium10benzimidazole;
hydroxamic acid;
olefinic compound;
tertiary amino compound		antimalarial;
antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor
spautin-1[no description available]medium10
ldn 57444[no description available]medium10
gsk1210151a[no description available]medium10imidazoquinoline
i-bet726[no description available]medium10
acy-1215[no description available]medium10pyrimidinecarboxylic acid
cudc-907[no description available]medium10
tasquinimod[no description available]medium10
gsk1265744[no description available]medium10difluorobenzene;
monocarboxylic acid amide;
organic heterotricyclic compound;
secondary carboxamide		HIV-1 integrase inhibitor
abt-267[no description available]medium10aromatic amide;
carbamate ester;
dipeptide;
pyrrolidines		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor
abt-333[no description available]medium10aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide		antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor
rgfp966[no description available]medium10
rg2833[no description available]medium10
pi-1840[no description available]medium10
acy-738[no description available]medium10
pelabresib[no description available]medium10monochlorobenzenes;
organic heterotricyclic compound;
primary carboxamide		antineoplastic agent;
bromodomain-containing protein 4 inhibitor
gs-5806[no description available]medium10
doravirine[no description available]medium10
gn6958[no description available]medium10
vx-787[no description available]medium10
ledipasvir[no description available]medium10azaspiro compound;
benzimidazole;
bridged compound;
carbamate ester;
carboxamide;
fluorenes;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organofluorine compound		antiviral drug;
hepatitis C protease inhibitor
gs-5816[no description available]medium10carbamate ester;
ether;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heteropentacyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor
g007-lk[no description available]medium10
4-((1-butyl-3-phenylureido)methyl)-n-hydroxybenzamide[no description available]medium10
selinexor[no description available]medium10
verdinexor[no description available]medium10
cb-839[no description available]medium10
mk-8742[no description available]medium10carbamate ester;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heterotetracyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor;
hepatoprotective agent
atglistatin[no description available]medium10
xen445[no description available]medium10
santacruzamate a[no description available]medium10organonitrogen compound;
organooxygen compound
ldc4297[no description available]medium10aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound		antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
enasidenib[no description available]medium101,3,5-triazines;
aminopyridine;
aromatic amine;
organofluorine compound;
secondary amino compound;
tertiary alcohol		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
s 8932[no description available]medium10aromatic amine;
C-nucleoside;
carboxylic ester;
nitrile;
phosphoramidate ester;
pyrrolotriazine		anticoronaviral agent;
antiviral drug;
prodrug
nu 1025[no description available]medium10phenols;
quinazolines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
4-hydroxyquinazoline[no description available]medium10quinazolines
azilsartan[no description available]medium101,2,4-oxadiazole;
aromatic ether;
benzimidazolecarboxylic acid		angiotensin receptor antagonist;
antihypertensive agent
hesperadin[no description available]medium10
6-bromoindirubin-3'-acetoxime[no description available]medium10
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide[no description available]medium10catechols;
hydrazide;
hydrazone;
naphthols		EC 3.6.5.5 (dynamin GTPase) inhibitor
XL413[no description available]medium10benzofuropyrimidine;
organochlorine compound;
pyrrolidines		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
me0328[no description available]medium10
nvp-tnks656[no description available]medium10
raloxifene hydrochloride[no description available]medium20hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
dan 2163[no description available]medium10aromatic amide;
aromatic amine;
benzamides;
pyrrolidines;
sulfone		environmental contaminant;
second generation antipsychotic;
xenobiotic
quetiapine fumarate[no description available]medium20fumarate salt
adenosine monophosphate[no description available]medium30adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
clopenthixol[no description available]high81N-alkylpiperazine;
primary alcohol;
thioxanthenes		alpha-adrenergic antagonist;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
flupenthixol[no description available]medium122thioxanthenes
paliperidone palmitate[no description available]medium101,2-benzoxazoles;
fatty acid ester;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine
cerium[no description available]medium10f-block element atom;
lanthanoid atom
ruthenium[no description available]medium10iron group element atom;
platinum group metal atom
fullerene c60[no description available]medium10fullerenegeroprotector
mefloquine[no description available]medium30
glycogen[no description available]medium100
semaxinib[no description available]medium10olefinic compound;
oxindoles;
pyrroles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist
pyrroles[no description available]medium40pyrrole;
secondary amine
cardiovascular agents[no description available]medium20
cuprizone[no description available]medium10organonitrogen compound;
organooxygen compound
sq-23377[no description available]medium210cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite
manganese[no description available]medium180elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
fura-2[no description available]medium90
fura-2-am[no description available]medium20
gold[no description available]medium10copper group element atom;
elemental gold
nadp[no description available]medium140
deoxycytidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pirfenidone[no description available]medium10pyridoneantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
erlotinib hydrochloride[no description available]medium20hydrochloride;
terminal acetylenic compound		antineoplastic agent;
protein kinase inhibitor
granisetron[no description available]medium10aromatic amide;
indazoles
rhizoxin[no description available]medium101,3-oxazoles;
epoxide;
macrolide antibiotic		antimitotic;
antineoplastic agent;
metabolite
maytansine[no description available]medium10alpha-amino acid ester;
carbamate ester;
epoxide;
maytansinoid;
organic heterotetracyclic compound;
organochlorine compound		antimicrobial agent;
antimitotic;
antineoplastic agent;
plant metabolite;
tubulin modulator
ansamitocins[no description available]medium10
glycolipids[no description available]medium50
thiazoles[no description available]medium301,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
methacrylic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid
ethylene dimethacrylate[no description available]medium10enoate esterallergen;
cross-linking reagent;
polymerisation monomer
yo-pro 1[no description available]medium10
benzoxazoles[no description available]medium201,3-benzoxazoles;
mancude organic heterobicyclic parent
oligonucleotides[no description available]medium10
alpha-bromonaphthalene[no description available]medium10
bromates[no description available]medium10bromine oxoanion;
monovalent inorganic anion
ophiobolin a[no description available]medium20cyclic ketone;
enal;
oxaspiro compound;
sesterterpenoid;
tertiary alcohol
alpha-synuclein[no description available]medium10
sodium azide[no description available]medium50inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen
calmidazolium[no description available]medium1450imidazolium ionapoptosis inducer;
calmodulin antagonist
mitotracker green fm[no description available]medium20
ganoderic acid b[no description available]medium10
camptothecin[no description available]medium10delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
4,6-dinitro-o-cresol[no description available]medium10dinitrophenol acaricide;
hydroxytoluene;
nitrotoluene		dinitrophenol insecticide;
fungicide;
herbicide
methdilazine[no description available]medium20N-alkylpyrrolidine;
phenothiazines		antipruritic drug;
cholinergic antagonist;
histamine antagonist
as 1842856[no description available]medium10organofluorine compound;
primary amino compound;
quinolinemonocarboxylic acid;
quinolone;
secondary amino compound;
tertiary amino compound		anti-obesity agent;
antineoplastic agent;
apoptosis inducer;
autophagy inhibitor;
forkhead box protein O1 inhibitor;
hypoglycemic agent
carbostyril[no description available]medium40monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
r 59949[no description available]medium10diarylmethane
piperidines[no description available]medium295
muromonab-cd3[no description available]medium10alkaloid;
macrocycle;
organic heteropentacyclic compound;
organonitrogen heterocyclic compound;
oxacycle;
tertiary amino compound		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
IP3 receptor antagonist;
marine metabolite
kn 93[no description available]medium40monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector
u 73122[no description available]medium50aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
oxazoles[no description available]medium501,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
nitrophenols[no description available]medium50
beta-escin[no description available]medium70
phytosterols[no description available]medium10
bongkrekic acid[no description available]medium20ether;
olefinic compound;
tricarboxylic acid		apoptosis inhibitor;
ATP/ADP translocase inhibitor;
bacterial metabolite;
EC 2.5.1.18 (glutathione transferase) inhibitor;
toxin
andrographolide[no description available]medium10carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol		anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite
hki 272[no description available]medium10nitrile;
quinolines		antineoplastic agent;
tyrosine kinase inhibitor
hesperidin[no description available]medium103'-hydroxyflavanones;
4'-methoxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
flavanone glycoside;
monomethoxyflavanone;
rutinoside		mutagen
hesperetin[no description available]medium103'-hydroxyflavanones;
4'-methoxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		antineoplastic agent;
antioxidant;
plant metabolite
pd 98059[no description available]medium20aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
ospemifene[no description available]medium10aromatic ether;
organochlorine compound;
primary alcohol		anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator
trifluoperazine dimaleate[no description available]medium50maleate salt
egtazic acid[no description available]medium1710diether;
tertiary amino compound;
tetracarboxylic acid		chelator
cyclosporine[no description available]medium410
oligomycins[no description available]medium60
cytochrome c-t[no description available]medium60
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid[no description available]medium10
thiourea[no description available]medium30one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
3-methyladenine[no description available]medium20
bromodeoxyuridine[no description available]medium50pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
afimoxifene[no description available]medium40phenols;
tertiary amino compound		antineoplastic agent;
estrogen receptor antagonist;
metabolite
trimetazidine[no description available]medium20aromatic amine
ammonium hydroxide[no description available]medium30azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
pyruvic acid[no description available]medium202-oxo monocarboxylic acidcofactor;
fundamental metabolite
cyclic gmp[no description available]medium3403',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
chetomin[no description available]medium10indoles;
organic disulfide;
organic heteropentacyclic compound		Chaetomium metabolite;
immunosuppressive agent
1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester[no description available]medium90
gamma-aminobutyric acid[no description available]medium190amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
isopropamide iodide[no description available]medium60diarylmethane
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide[no description available]medium190naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide
lignin[no description available]medium20
cobalt[no description available]medium70cobalt group element atom;
metal allergen		micronutrient
cobaltous chloride[no description available]medium20cobalt salt;
inorganic chloride		allergen;
calcium channel blocker;
sensitiser;
two-colour indicator
destruxin a[no description available]medium10
abscisic acid[no description available]medium202-trans-abscisic acid
pempidine[no description available]medium20piperidines
benzethonium[no description available]medium10alkylbenzene
melitten[no description available]medium210
nickel[no description available]medium60metal allergen;
nickel group element atom		epitope;
micronutrient
histidine[no description available]medium30amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
methylbenzethonium chloride[no description available]medium10alkylbenzene
D-fructopyranose[no description available]medium50cyclic hemiketal;
D-fructose;
fructopyranose		sweetening agent
1,2-oleoylphosphatidylcholine[no description available]medium10phosphatidylcholine(1+)
phosphatidylcholines[no description available]medium1901,2-diacyl-sn-glycero-3-phosphocholine
monobromobimane[no description available]medium10organobromine compound;
pyrazolopyrazole		fluorochrome
nicotine n-glucuronide[no description available]medium10iminium betaine;
N-glycosylpyridine		metabolite
n-(6-aminohexyl)-1-naphthalenesulfonamide[no description available]medium370naphthalenes;
sulfonic acid derivative
calpain[no description available]medium40
gigantol[no description available]medium10
uridine diphosphate glucuronic acid[no description available]medium10UDP-D-glucuronic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
eslicarbazepine acetate[no description available]medium10acetate ester;
carboxamide;
dibenzoazepine;
ureas		anticonvulsant;
drug allergen
cytochalasin e[no description available]medium10cytochalasan alkaloidmetabolite
cytochalasin d[no description available]medium130
brefeldin a[no description available]medium20macrolide antibioticPenicillium metabolite
phalloidine[no description available]medium20homodetic cyclic peptide
cytochalasin a[no description available]medium10cytochalasin
1,3-dimethylthiourea[no description available]medium10
hydrogen sulfide[no description available]medium20gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent
sodium bisulfide[no description available]medium10
ro 25-6981[no description available]medium10benzenes;
phenols;
piperidines;
secondary alcohol;
tertiary amino compound		anticonvulsant;
antidepressant;
neuroprotective agent;
NMDA receptor antagonist
dianisidine[no description available]medium10biphenyls
thioproperazine[no description available]high130N-alkylpiperazine;
N-methylpiperazine;
phenothiazines;
sulfonamide		phenothiazine antipsychotic drug
quinazolines[no description available]medium40azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
tanshinone[no description available]medium10abietane diterpenoidanticoronaviral agent
tetrodotoxin[no description available]medium130azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
guanosine triphosphate[no description available]medium80guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
endothelin-1[no description available]medium20
angiotensin ii[no description available]medium250amino acid zwitterion;
angiotensin II		human metabolite
pituitrin[no description available]medium220
dantrolene[no description available]medium150hydrazone;
imidazolidine-2,4-dione		muscle relaxant;
neuroprotective agent;
ryanodine receptor antagonist
inositol 1,4,5-trisphosphate[no description available]medium100myo-inositol trisphosphatemouse metabolite
bradykinin[no description available]medium130oligopeptidehuman blood serum metabolite;
vasodilator agent
thallium[no description available]medium10boron group element atom
4-chloro-7-nitrobenzofurazan[no description available]medium20benzoxadiazole;
C-nitro compound;
organochlorine compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome
n-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine[no description available]medium10N-acylsphingosinefluorescent probe
n-methylaspartate[no description available]medium20amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
kainic acid[no description available]medium50dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
bucladesine[no description available]medium4403',5'-cyclic purine nucleotide
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid[no description available]medium20non-proteinogenic alpha-amino acid
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium380isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
glutamic acid[no description available]medium180glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
rmi 12330a[no description available]medium60
ryanodine[no description available]medium60
gossypol[no description available]medium30
xestospongin a[no description available]medium10
scoparone[no description available]medium10aromatic ether;
coumarins		anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite
sesquiterpenes[no description available]medium40
pyrethrins[no description available]medium10
ng-nitroarginine methyl ester[no description available]medium70alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
veratridine[no description available]medium70
decamethrin[no description available]medium10aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound		agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide
kn 62[no description available]medium100piperazines
indazoles[no description available]medium10indazole
staurosporine[no description available]medium290ammonium ion derivative
chlorophyll a[no description available]medium10chlorophyll;
methyl ester		cofactor
u 73343[no description available]medium20
mlck peptide[no description available]medium10
staurosporine aglycone[no description available]medium50
glycyl-arginyl-glycyl-aspartyl-seryl-proline[no description available]medium10
hydrogen cyanide[no description available]medium10hydracid;
one-carbon compound		Escherichia coli metabolite;
human metabolite;
poison
gliotoxin[no description available]medium10dipeptide;
organic disulfide;
organic heterotetracyclic compound;
pyrazinoindole		antifungal agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
immunosuppressive agent;
mycotoxin;
proteasome inhibitor
osteoprotegerin[no description available]medium10long-chain fatty acid
parstelin[no description available]medium30
amobarbital[no description available]medium262barbiturates
iodine[no description available]medium20diatomic iodinenutrient
prothipendyl[no description available]medium40aromatic amine;
tertiary amino compound
fluorine[no description available]medium120diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
pheniprazine[no description available]medium10amphetamines
phosphorus[no description available]medium40monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
methysergide[no description available]medium40ergoline alkaloid
phenmetrazine[no description available]medium60morpholinesmetabolite;
sympathomimetic agent
choline[no description available]medium130cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
naphthoquinones[no description available]medium10
azides[no description available]medium80pseudohalide anionmitochondrial respiratory-chain inhibitor
cyanides[no description available]medium60pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
neotetrazolium[no description available]medium10
ubiquinone[no description available]medium10
salicylates[no description available]medium60monohydroxybenzoateplant metabolite
deanol[no description available]medium50ethanolamines;
tertiary amine		curing agent;
radical scavenger
benactyzine[no description available]medium200diarylmethane
lithium[no description available]medium295alkali metal atom
beta-aminoethyl isothiourea[no description available]medium10
17-ketosteroids[no description available]medium20
niacinamide[no description available]medium20pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
syrosingopine[no description available]medium10yohimban alkaloid
ergotamine[no description available]medium40peptide ergot alkaloidalpha-adrenergic agonist;
mycotoxin;
non-narcotic analgesic;
oxytocic;
serotonergic agonist;
vasoconstrictor agent
urea[no description available]medium60isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
oxypertine[no description available]medium10organic molecular entity
sucrose[no description available]medium40glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
chlorine[no description available]medium370halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
benzquinamide[no description available]medium10monocarboxylic acid amideantiemetic;
antipsychotic agent;
H1-receptor antagonist;
muscarinic antagonist;
sedative
pipradrol[no description available]medium10diarylmethane
hydroxyindoleacetic acid[no description available]medium70indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
indoleacetic acid[no description available]medium10indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
dihydroxyphenylalanine[no description available]medium90hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
tryptophan[no description available]medium70erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
virginiamycin[no description available]medium10
dalfopristin[no description available]medium10
quinupristin[no description available]medium10cyclodepsipeptide
oxazolidin-2-one[no description available]medium10carbamate ester;
oxazolidinone		metabolite
gadolinium[no description available]medium10f-block element atom;
lanthanoid atom
serine[no description available]medium40L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
7-hydroxy-4-trifluoromethylcoumarin[no description available]medium10
triazoles[no description available]medium101,2,3-triazole
rhodamine 123[no description available]medium30organic cation;
xanthene dye		fluorochrome
lanthanum[no description available]medium260f-block element atom;
lanthanoid atom;
scandium group element atom
lanthanum chloride[no description available]medium60
sudan iii[no description available]medium10azobenzenes;
bis(azo) compound;
naphthols		carcinogenic agent;
fluorochrome;
histological dye
nile red[no description available]medium10aromatic amine;
cyclic ketone;
organic heterotetracyclic compound;
tertiary amino compound		fluorochrome;
histological dye
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene[no description available]medium10BODIPY compound
1,2-dipalmitoylphosphatidylglycerol[no description available]medium10phosphatidylglycerol
1,2-dipalmitoylphosphatidylcholine[no description available]medium30
l 012[no description available]medium10
luminol[no description available]medium20
arachidonic acid[no description available]medium400icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
chondroitin sulfates[no description available]medium10
sepharose[no description available]medium20
lactoferrin[no description available]medium20
transferrin[no description available]medium40
nad[no description available]medium100organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
phosphoserine[no description available]medium60non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative		human metabolite
phosphotyrosine[no description available]medium40L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine		Escherichia coli metabolite;
immunogen
okadaic acid[no description available]medium230ketal
phosphothreonine[no description available]medium30L-threonine derivative;
non-proteinogenic L-alpha-amino acid;
O-phosphoamino acid		Escherichia coli metabolite
vanadates[no description available]medium290trivalent inorganic anion;
vanadium oxoanion		EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
dimyristoylphosphatidylcholine[no description available]medium301,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
cyclin d1[no description available]medium10
dichlororibofuranosylbenzimidazole[no description available]medium10
deacetoxyvinzolidine[no description available]medium30
guanosine 5'-o-(3-thiotriphosphate)[no description available]medium70nucleoside triphosphate analogue
cgp 7930[no description available]medium10alkylbenzene
1-(4-methoxyphenyl)pyridinium[no description available]medium10
daunorubicinol[no description available]medium1013-dihydrodaunorubicin
cadaverine[no description available]medium60alkane-alpha,omega-diamineDaphnia magna metabolite;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite
monodansylcadaverine[no description available]medium50aminonaphthalene;
primary amino compound;
sulfonamide;
tertiary amino compound		EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor;
fluorochrome;
protective agent
leupeptins[no description available]medium60
3-nitropropionic acid[no description available]medium10C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin
diacetyl[no description available]medium10alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite
diacetylmonoxime[no description available]medium10
blister[no description available]medium10cyclic ketone;
pyrroloquinoline;
tertiary alcohol;
tertiary alpha-hydroxy ketone		inhibitor
alamethicin[no description available]medium20
1-methyl-4-phenylpyridinium[no description available]medium10pyridinium ionapoptosis inducer;
herbicide;
human xenobiotic metabolite;
neurotoxin
heme[no description available]medium20
carbachol[no description available]medium360ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
ferric sulfate[no description available]medium10iron molecular entity;
metal sulfate		astringent;
catalyst;
mordant
dithiothreitol[no description available]medium501,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
sphingosine[no description available]medium100sphing-4-eninehuman metabolite;
mouse metabolite
sphingosine 1-phosphate[no description available]medium10sphingoid 1-phosphatemouse metabolite;
signalling molecule;
sphingosine-1-phosphate receptor agonist;
T-cell proliferation inhibitor;
vasodilator agent
hygromycin a[no description available]medium10hydroxycinnamic acidmetabolite
hygromycin b[no description available]medium10
magnesium sulfate[no description available]medium41magnesium salt;
metal sulfate;
organic magnesium salt		anaesthetic;
analgesic;
anti-arrhythmia drug;
anticonvulsant;
calcium channel blocker;
cardiovascular drug;
fertilizer;
tocolytic agent
omega-n-methylarginine[no description available]medium80amino acid zwitterion;
arginine derivative;
guanidines;
L-arginine derivative;
non-proteinogenic L-alpha-amino acid
propane[no description available]medium10alkane;
gas molecular entity		food propellant
strontium[no description available]medium50alkaline earth metal atom
iodoacetamide[no description available]medium10
lysophosphatidic acid[no description available]medium101-acyl-sn-glycerol 3-phosphate
cysteine[no description available]medium10cysteiniumfundamental metabolite
merocyanine dye[no description available]medium10
pyrimidinones[no description available]medium10
kaolinite[no description available]medium10aluminosilicate mineral;
mixture		antidiarrhoeal drug;
excipient
substance p[no description available]medium40peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
p-methoxy-n-methylphenethylamine[no description available]medium270aromatic ether;
secondary amino compound		metabolite
sodium fluoride[no description available]medium80fluoride saltmutagen
concanavalin a[no description available]medium140
enkephalin, methionine[no description available]medium60
cetiedil[no description available]medium10azepanes
tetradecanoylphorbol acetate[no description available]medium980acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
phorbols[no description available]medium130diterpene;
terpenoid fundamental parent
oleic acid[no description available]medium50octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
n-formylmethionine leucyl-phenylalanine[no description available]medium190tripeptide
phosphorus radioisotopes[no description available]medium110
tyrosine[no description available]medium90amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
linoleic acid[no description available]medium40octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
benzoyltyrosine ethyl ester[no description available]medium10benzamides;
ethyl ester;
L-tyrosine derivative;
phenols		chromogenic compound
vasoactive intestinal peptide[no description available]medium70
rubidium[no description available]medium70alkali metal atom
6-ketoprostaglandin f1 alpha[no description available]medium100prostaglandins Falphahuman metabolite;
mouse metabolite
muramidase[no description available]medium70
deoxyglucose[no description available]medium110
leukotriene b4[no description available]medium40dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
cyanogen bromide[no description available]medium20
potassium chloride[no description available]medium170inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid[no description available]medium110
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]medium70stilbenoid
nitrates[no description available]medium20monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
16,16-dimethylprostaglandin e2[no description available]medium10cyclopentanones;
monocarboxylic acid;
prostanoid;
secondary allylic alcohol		anti-ulcer drug;
gastrointestinal drug;
radiation protective agent
8-bromo cyclic adenosine monophosphate[no description available]medium1003',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
3,4-dihydroxyphenylacetic acid[no description available]medium90catechols;
dihydroxyphenylacetic acid		human metabolite
fluoracizine[no description available]medium30phenothiazines
phenazepam[no description available]medium40
dihydroalprenolol[no description available]medium30
thiothixene[no description available]medium326thioxanthenes
phenylephrine[no description available]medium100phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
adtn[no description available]medium10
glucagon[no description available]medium140peptide hormone
dibutyryl cyclic gmp[no description available]medium40
1,2-cyclohexanedione[no description available]medium10cyclohexanedione
tiletamine hydrochloride[no description available]medium20
ammonium chloride[no description available]medium50ammonium salt;
inorganic chloride		ferroptosis inhibitor
dihydroergotoxine[no description available]medium10
prenalterol[no description available]medium10aromatic ether
alpha-chymotrypsin[no description available]medium10
adenosine diphosphate[no description available]medium150adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
homocysteine[no description available]medium10amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
homocysteic acid[no description available]medium10homocysteic acidNMDA receptor agonist
hyaluronoglucosaminidase[no description available]medium20
vanadium[no description available]medium110elemental vanadium;
vanadium group element atom		micronutrient
talipexole[no description available]medium20azepine
glyceraldehyde[no description available]medium10aldotriosefundamental metabolite
butaclamol[no description available]medium20
phosphocreatine[no description available]medium30phosphagen;
phosphoamino acid		human metabolite;
mouse metabolite
antimycin a[no description available]medium90amidobenzoic acid
isethionic acid[no description available]medium20alkanesulfonic acidhuman metabolite
gramicidin a[no description available]medium10
1-isoamyl-3-isobutylxanthine[no description available]medium10
cholecystokinin[no description available]medium20
thromboxane b2[no description available]medium80thromboxanes Bhuman metabolite;
mouse metabolite
thromboxanes[no description available]medium20
dinoprost[no description available]medium70monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
oxalic acid[no description available]medium20alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
oxalates[no description available]medium30
22-hydroxycholesterol[no description available]medium10cholanoid
trifluoperazine sulfoxide[no description available]medium60
mercuric chloride[no description available]medium20mercury coordination entitysensitiser
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
chromium[no description available]medium10chromium group element atom;
metal allergen		micronutrient
fucose[no description available]medium10fucopyranose;
L-fucose		Escherichia coli metabolite;
mouse metabolite
digitonin[no description available]medium100
20-alpha-dihydroprogesterone[no description available]medium1020-hydroxypregn-4-en-3-onehuman metabolite;
mouse metabolite
n-formylmethionine[no description available]medium40L-methionine derivative;
N-formyl amino acid;
proteinogenic amino acid		metabolite
palmitoylcarnitine[no description available]medium40O-palmitoylcarnitine;
saturated fatty acyl-L-carnitine		EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
human metabolite;
mouse metabolite
palmitoyl coenzyme a[no description available]medium1011,12-saturated fatty acyl-CoA;
3-substituted propionyl-CoA;
long-chain fatty acyl-CoA;
palmitoyl bioconjugate		Escherichia coli metabolite;
mouse metabolite
chlortetracycline[no description available]medium40
n-formylmethionyl-methionyl-phenylalanine[no description available]medium10
glycerophosphoinositol 4,5-bisphosphate[no description available]medium50
harmaline[no description available]medium10harmala alkaloidoneirogen
galactosamine[no description available]medium20D-galactosamine;
primary amino compound		toxin
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
lead[no description available]medium30carbon group element atom;
elemental lead;
metal atom		neurotoxin
citric acid, anhydrous[no description available]medium40tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
barium[no description available]medium140alkaline earth metal atom;
elemental barium
barium chloride[no description available]medium40barium salt;
inorganic chloride		potassium channel blocker
arsenazo iii[no description available]medium30
hydrogen[no description available]medium50elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
epidermal growth factor[no description available]medium120
adenylyl imidodiphosphate[no description available]medium20adenosine 5'-phosphate
hydroxyl radical[no description available]medium20oxygen hydride;
oxygen radical;
reactive oxygen species
gastrins[no description available]medium30
phosphatidylinositol 4-phosphate[no description available]medium30
glucose-1,6-bisphosphate[no description available]medium30D-glucose 1,6-bisphosphateEscherichia coli metabolite;
human metabolite
1-hexadecyl-2-acetyl-glycero-3-phosphocholine[no description available]medium902-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
2-(4-toluidino)-6-naphthalenesulfonic acid[no description available]medium10
technetium[no description available]medium20manganese group element atom
1-methylimidazole[no description available]medium10imidazoles
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]medium10
lasalocid[no description available]medium10beta-hydroxy ketone;
monocarboxylic acid;
monohydroxybenzoic acid;
oxanes;
oxolanes;
polyether antibiotic;
secondary alcohol;
tertiary alcohol		bacterial metabolite;
coccidiostat;
ionophore
n-hydroxysuccinimide suberic acid ester[no description available]medium10
9,10-dimethyl-1,2-benzanthracene[no description available]medium20ortho-fused polycyclic arene;
tetraphenes		carcinogenic agent
teleocidin b-4[no description available]medium10
threonine[no description available]medium10amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
caseins[no description available]medium30
phorbol-12,13-didecanoate[no description available]medium30
glucose, (beta-d)-isomer[no description available]medium50D-glucopyranoseepitope;
mouse metabolite
amsacrine[no description available]medium20acridines;
aromatic ether;
sulfonamide		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
deoxycholic acid[no description available]medium30bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
guanylyl imidodiphosphate[no description available]medium50nucleoside triphosphate analogue
glycerol[no description available]medium50alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
imidazole[no description available]medium30imidazole
1-methyladenine[no description available]medium10
valinomycin[no description available]medium70cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
carbidopa[no description available]medium20
5-hydroxytryptophan[no description available]medium40hydroxytryptophanhuman metabolite;
neurotransmitter
methylamine[no description available]medium40methylamines;
one-carbon compound;
primary aliphatic amine		mouse metabolite
enkephalin, leucine[no description available]medium60pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
tuftsin[no description available]medium10peptide
thymidine[no description available]medium80pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
cadmium[no description available]medium120cadmium molecular entity;
zinc group element atom
w 12[no description available]medium60naphthalenes;
sulfonic acid derivative
ristocetin[no description available]medium10glycopeptide;
heterodetic cyclic peptide;
macrocycle;
tetrasaccharide derivative		antibacterial drug;
antimicrobial agent;
bacterial metabolite;
platelet-activating factor receptor agonist
hexadimethrine bromide[no description available]medium10
d-ala(2),mephe(4),met(0)-ol-enkephalin[no description available]medium10
theobromine[no description available]medium10dimethylxanthineadenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
prostaglandin f1[no description available]medium10prostaglandins Falphahuman metabolite
1-anilino-8-naphthalenesulfonate[no description available]medium40aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
dihydroxyacetone[no description available]medium10ketotriose;
primary alpha-hydroxy ketone		antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
lysophosphatidylcholines[no description available]medium401-O-acyl-sn-glycero-3-phosphocholine
putrescine[no description available]medium40alkane-alpha,omega-diamineantioxidant;
fundamental metabolite
sidnocarb[no description available]medium10
oxadiazoles[no description available]medium10
carbobenzoxyphenylalanylmethionine[no description available]medium10
caroverine[no description available]medium10quinoxaline derivative
quinoxalines[no description available]medium30mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
darodipine[no description available]medium10
methandrostenolone[no description available]medium10organic molecular entity
fibrinogen[no description available]medium20iditolfungal metabolite
mastoparan[no description available]medium70mastoparans;
peptidyl amide		antimicrobial agent
zy 17617b[no description available]medium130
myelin basic protein[no description available]medium10
2,6-dichloroindophenol[no description available]medium10dichlorobenzene;
quinone imine
tempo[no description available]medium10aminoxyls;
piperidines		catalyst;
ferroptosis inhibitor;
radical scavenger
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid[no description available]medium10chromanol;
monocarboxylic acid;
phenols		antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radical scavenger;
Wnt signalling inhibitor
citrulline[no description available]medium20amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
masoprocol[no description available]medium100nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite
taurine[no description available]medium110amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
hydrogen carbonate[no description available]medium40carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
nitroarginine[no description available]medium40guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
canavanine[no description available]medium20amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		phytogenic insecticide;
plant metabolite
antipyrylazo iii[no description available]medium10
niflumic acid[no description available]medium40aromatic carboxylic acid;
pyridines
resiniferatoxin[no description available]medium20carboxylic ester;
diterpenoid;
enone;
monomethoxybenzene;
organic heteropentacyclic compound;
ortho ester;
phenols;
tertiary alpha-hydroxy ketone		analgesic;
neurotoxin;
plant metabolite;
TRPV1 agonist
pectins[no description available]medium10D-galactopyranuronic acid
1-oleoyl-2-acetylglycerol[no description available]medium801,2-diglyceride
gibberellins[no description available]medium10
sodium cyanide[no description available]medium20cyanide salt;
one-carbon compound;
sodium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor
alanine[no description available]medium40alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
arsenic acid[no description available]medium10arsenic oxoacidEscherichia coli metabolite
1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid[no description available]medium110polyamino carboxylic acid;
tetracarboxylic acid		chelator
n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide[no description available]medium40isoquinolines;
sulfonamide
aluminum[no description available]medium20boron group element atom;
elemental aluminium;
metal atom
fluorexon[no description available]medium10xanthene dyefluorochrome
tert-butylhydroperoxide[no description available]medium50alkyl hydroperoxideantibacterial agent;
oxidising agent
calcein am[no description available]medium102-benzofurans;
acetate ester;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
xanthene dye		fluorochrome
erythrosine[no description available]medium30
sk&f-38393[no description available]medium20benzazepine;
catechols;
secondary amino compound
1h-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-[no description available]medium10benzazepine
bombykol[no description available]medium10long-chain primary fatty alcoholpheromone
muscarine[no description available]medium10monosaccharide
lithium chloride[no description available]medium10inorganic chloride;
lithium salt		antimanic drug;
geroprotector
glycochenodeoxycholic acid[no description available]medium10bile acid glycine conjugatehuman metabolite
leucine[no description available]medium80amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ubenimex[no description available]medium10
thiorphan[no description available]medium10N-acyl-amino acid
mannose[no description available]medium10D-aldohexose;
D-mannose;
mannopyranose		metabolite
cytidine diphosphate choline[no description available]medium10nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
fluorides[no description available]medium20halide anion;
monoatomic fluorine
2-amino-5-phosphonovalerate[no description available]medium10non-proteinogenic alpha-amino acidNMDA receptor antagonist
6-cyano-7-nitroquinoxaline-2,3-dione[no description available]medium20quinoxaline derivative
glycine[no description available]medium60alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
quinpirole[no description available]medium10pyrazoloquinolinedopamine agonist
ergoline[no description available]medium10diamine;
ergoline alkaloid;
indole alkaloid fundamental parent;
indole alkaloid;
organic heterotetracyclic compound
ro13-9904[no description available]medium10
azobis(isobutyronitrile)[no description available]medium10
tetrazepam[no description available]medium10benzodiazepine
transforming growth factor beta[no description available]medium10
spermine[no description available]medium80polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
spermidine[no description available]medium60polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
ifenprodil[no description available]medium20piperidines
phenyl acetate[no description available]medium70benzenes;
phenyl acetates
xylenol orange[no description available]medium10
beta-escin[no description available]medium30triterpenoid saponin
atrial natriuretic factor[no description available]medium30polypeptide
8-((4-chlorophenyl)thio)cyclic-3',5'-amp[no description available]medium203',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
aryl sulfide;
organochlorine compound		protein kinase agonist
chlorethylclonidine[no description available]medium10
aspartic acid[no description available]medium50aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
4-desmethoxyverapamil[no description available]medium10
quisqualic acid[no description available]medium20non-proteinogenic alpha-amino acid
raclopride[no description available]medium20salicylamides
n-n-propylnorapomorphine[no description available]medium10
metylperon[no description available]medium10aromatic ketone
peptide elongation factor 2[no description available]medium40
cadmium chloride[no description available]medium40cadmium coordination entity
metallothionein[no description available]medium10
ly 274614[no description available]medium10
zinc sulfate[no description available]medium20metal sulfate;
zinc molecular entity		fertilizer
n-acetylneuraminic acid[no description available]medium20N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
diamide[no description available]medium101,1'-azobis(N,N-dimethylformamide)
cytidine triphosphate[no description available]medium50cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
inosine triphosphate[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
diazobenzenesulfonic acid[no description available]medium10
phorbol 12,13-dibutyrate[no description available]medium50butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone
nsc 65346[no description available]medium10nucleoside analogueprotein kinase inhibitor
lucifer yellow[no description available]medium10organic lithium saltfluorochrome
nicorandil[no description available]medium10nitrate ester;
pyridinecarboxamide		potassium channel opener;
vasodilator agent
cromakalim[no description available]medium10
n-cyano-n'-(2-nitroxyethyl)-3-pyridinecarboximidamide methanesulfonate[no description available]medium10
lactic acid[no description available]medium702-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
8-bromocyclic gmp[no description available]medium203',5'-cyclic purine nucleotide;
organobromine compound		muscle relaxant;
protein kinase G agonist
charybdotoxin[no description available]medium10
hydrochloric acid[no description available]medium40chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
desethylamiodarone[no description available]medium20aromatic ketone
dibenzepin[no description available]medium10dibenzodiazepine
ethidium[no description available]medium20phenanthridinesfluorochrome;
intercalator
n-(8-aminooctyl)-5-iodonaphthalene-1-sulfonamide[no description available]medium20
maitotoxin[no description available]medium20
safranine t[no description available]medium20organic chloride saltfluorochrome;
histological dye
ferrous citrate[no description available]medium10
capsazepine[no description available]medium10benzazepine;
catechols;
monochlorobenzenes;
thioureas		capsaicin receptor antagonist
rimcazole[no description available]medium10carbazoles
fenton's reagent[no description available]medium10
mustard gas[no description available]medium20ethyl sulfide;
organochlorine compound		alkylating agent;
carcinogenic agent;
vesicant
dimethyl sulfoxide[no description available]medium70sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
fluorescein-5-isothiocyanate[no description available]medium20fluorescein isothiocyanate
n-nitrosomorpholine[no description available]medium10nitrosaminecarcinogenic agent;
mutagen
pimagedine[no description available]medium20guanidines;
one-carbon compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor
ornithine[no description available]medium10non-proteinogenic L-alpha-amino acid;
ornithine		algal metabolite;
hepatoprotective agent;
mouse metabolite
n(g)-iminoethylornithine[no description available]medium10L-alpha-amino acid
tissue plasminogen activator[no description available]medium10alpha-amino acid
technetium tc 99m exametazime[no description available]medium10
n,n'-diphenyl-4-phenylenediamine[no description available]medium10N-substituted diamine;
secondary amino compound		antioxidant
berberine[no description available]medium10alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker
carboxyatractyloside[no description available]medium10
atractyloside[no description available]medium10
resazurin[no description available]medium10phenoxazine
xanthenes[no description available]medium115xanthene
indo-1[no description available]medium10indolesfluorochrome
ucn 1028 c[no description available]medium30
centchroman[no description available]medium10
cdri 85-287[no description available]medium10
brazilin[no description available]medium101-benzopyran
moclobemide[no description available]medium10benzamides;
monochlorobenzenes;
morpholines		antidepressant;
environmental contaminant;
xenobiotic
nordazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative
4-bromophenacyl bromide[no description available]medium60
xanthine[no description available]medium20xanthineSaccharomyces cerevisiae metabolite
guanosine 5'-o-(2-thiodiphosphate)[no description available]medium10nucleoside diphosphate analogue
guanosine diphosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
dizocilpine maleate[no description available]medium10maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine[no description available]medium10cyanine dye;
indolium ion		fluorochrome
carbocyanines[no description available]medium10cyanine dye;
organic iodide salt		fluorochrome
pyrrolidonecarboxylic acid[no description available]medium205-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
benzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
acridine half-mustard[no description available]medium10aminoacridines;
aromatic ether;
organochlorine compound;
secondary amino compound		mutagen
sodium bichromate[no description available]medium10inorganic sodium salt
chromates[no description available]medium10chromium oxoanion;
divalent inorganic anion		oxidising agent
flavin-adenine dinucleotide[no description available]medium30flavin adenine dinucleotide;
vitamin B2		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group
palladium[no description available]medium10metal allergen;
nickel group element atom;
platinum group metal atom
tin[no description available]medium10carbon group element atom;
elemental tin;
metal atom		micronutrient
protein kinase c[no description available]medium10
7,8-dimethylalloxazine[no description available]medium207,8-dimethylbenzo[g]pteridine-2,4-dioneplant metabolite
lumiflavin[no description available]medium10flavin
thiazolidines[no description available]medium10thiazolidine
interleukin-8[no description available]medium20
arabinogalactan[no description available]medium10
arabinose[no description available]medium10L-arabinoseEscherichia coli metabolite;
mouse metabolite
galactose[no description available]medium60D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
apyrase[no description available]medium10
crocin[no description available]medium10
p(3)-1-(2-nitro)phenylethyladenosine 5'-triphosphate[no description available]medium10
phenylalanylalanine[no description available]medium10dipeptide zwitterion;
dipeptide		metabolite
raffinose[no description available]medium40raffinose family oligosaccharide;
trisaccharide		mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ethylisopropylamiloride[no description available]medium20aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker
24,25-dihydroxyvitamin d 3[no description available]medium10
ml 9[no description available]medium30
ml 7[no description available]medium10N-sulfonyldiazepane;
organoiodine compound		EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
fm1 43[no description available]medium10organic bromide salt;
pyridinium salt;
quaternary ammonium salt;
tertiary amine		fluorochrome
tetraethylammonium[no description available]medium20quaternary ammonium ion
venlafaxine hydrochloride[no description available]medium10hydrochloride
cyclohexanol[no description available]medium10cyclohexanols;
secondary alcohol		solvent
u 18666a[no description available]medium20hydrochlorideantiviral agent;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
Hedgehog signaling pathway inhibitor;
nicotinic antagonist;
sterol biosynthesis inhibitor
dinitrofluorobenzene[no description available]medium10C-nitro compound;
organofluorine compound		agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent
calyculin a[no description available]medium10
kt 5720[no description available]medium10carboxylic ester;
gamma-lactam;
hemiaminal;
indolocarbazole;
organic heterooctacyclic compound;
semisynthetic derivative;
tertiary alcohol		EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
adenosine-3',5'-cyclic phosphorothioate[no description available]medium10nucleoside 3',5'-cyclic phosphorothioate
5-(n,n-hexamethylene)amiloride[no description available]medium10aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker
pd 123319[no description available]medium10imidazopyridineangiotensin receptor antagonist;
endothelin receptor antagonist;
vasoconstrictor agent
meglumine[no description available]medium20hexosamine;
secondary amino compound
thiazolyl blue[no description available]medium10organic bromide saltcolorimetric reagent;
dye
dinitrobenzenes[no description available]medium20
diphenic acid[no description available]medium10dicarboxylic acid
pirmagrel[no description available]medium10
eflornithine[no description available]medium10alpha-amino acid;
fluoroamino acid		trypanocidal drug
mdl 72527[no description available]medium10
sodium selenite[no description available]medium10inorganic sodium salt;
selenite salt		nutraceutical
3,4-dihydroxyphenylacetaldehyde[no description available]medium10alpha-CH2-containing aldehyde;
catechols;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
4-aminobenzoic acid[no description available]medium10aminobenzoic acid;
aromatic amino-acid zwitterion		allergen;
Escherichia coli metabolite;
plant metabolite
aristolochic acid i[no description available]medium10aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
4-aminobenzoic acid[no description available]medium10aminobenzoate;
aromatic amino-acid anion		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenanthrenes[no description available]medium20
laurdan[no description available]medium10
2-(methylamino)isobutyric acid[no description available]medium10alanine derivative;
alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
secondary amino compound		human urinary metabolite
2-aminobicyclo(2,2,1)heptane-2-carboxylic acid[no description available]medium10monoterpenoid
1-amino-1,3-dicarboxycyclopentane[no description available]medium10
domoic acid[no description available]medium10L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid;
tricarboxylic acid		algal metabolite;
hapten;
marine metabolite;
neuromuscular agent;
neurotoxin
cycloleucine[no description available]medium10non-proteinogenic alpha-amino acidEC 2.5.1.6 (methionine adenosyltransferase) inhibitor
b 1287[no description available]medium10organic sodium salt
lipid a[no description available]medium10dodecanoate ester;
lipid A;
tetradecanoate ester		Escherichia coli metabolite
e 5531[no description available]medium10
phosphatidylethanol[no description available]medium10
11-cis-retinal[no description available]medium10retinalchromophore;
human metabolite;
mouse metabolite
suramin[no description available]medium10naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
1,4-dihydropyridine[no description available]medium10
dihydropyridines[no description available]medium40
1,3-dibromo-5,5-dimethylhydantoin[no description available]medium10
bromine[no description available]medium20diatomic bromine
hydantoins[no description available]medium10imidazolidine-2,4-dione
trehalose[no description available]medium10trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
glutamyl-leucyl-threonyl-phenylalanyl-threonyl-prolyl-asparaginyl-tryptophanamide[no description available]medium10
diphenylhexatriene[no description available]medium10alkatrienefluorochrome
palmitic acid[no description available]medium20long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite
methoxybenzanthrone[no description available]medium10
cosyntropin[no description available]medium10
piribedil[no description available]medium20N-arylpiperazine
cyamemazine[no description available]medium10phenothiazines
sulfur[no description available]medium10chalcogen;
nonmetal atom		macronutrient
uridine[no description available]medium30uridinesdrug metabolite;
fundamental metabolite;
human metabolite
nordefrin[no description available]medium10catecholamine
phenylphosphonothioic acid, 2-ethyl 2-(4-nitrophenyl) ester[no description available]medium10organic phosphonate;
organothiophosphate insecticide;
phosphonic ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
aminopyrine[no description available]medium20pyrazolone;
tertiary amino compound		antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
oxotremorine[no description available]medium30N-alkylpyrrolidine
4-butyrolactone[no description available]medium10butan-4-olidemetabolite;
neurotoxin
flavin mononucleotide[no description available]medium10
3-amino-6-methyl-5-phenyl-2(1h)-pyridinone[no description available]medium20
uridine triphosphate[no description available]medium10pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
wb 4101[no description available]medium10aromatic ether;
benzodioxine;
secondary amino compound		alpha-adrenergic antagonist
malondialdehyde[no description available]medium30dialdehydebiomarker
methylnitronitrosoguanidine[no description available]medium10nitroso compoundalkylating agent
flunitrazepam[no description available]medium201,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes		anxiolytic drug;
GABAA receptor agonist;
sedative
dicarbine[no description available]medium10
tiapamil hydrochloride[no description available]medium10
neurokinin a[no description available]medium10
neurokinin b[no description available]medium10polypeptide
zinc chloride[no description available]medium20inorganic chloride;
zinc molecular entity		astringent;
disinfectant;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
Lewis acid
fructose 2,6-diphosphate[no description available]medium10D-fructofuranose 2,6-bisphosphatehuman metabolite;
mouse metabolite
antipain[no description available]medium10
1,2-didecanoylglycerol[no description available]medium101,2-diglyceride;
decanoate ester
1,2-dioctanoylglycerol[no description available]medium20
lactobionic acid[no description available]medium10disaccharideantioxidant
diethylhexyl phthalate[no description available]medium10diester;
phthalate ester		androstane receptor agonist;
apoptosis inhibitor;
plasticiser
sipi 549[no description available]medium10
dithionitrobenzoic acid[no description available]medium30nitrobenzoic acid;
organic disulfide		indicator
azidopine[no description available]medium20benzamides
g(m1) ganglioside[no description available]medium20alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide
n-acetylneuraminyl cholesterol[no description available]medium10
desmosine[no description available]medium10aromatic amino acid
hydroxyproline[no description available]medium104-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
phloretin[no description available]medium50dihydrochalconesantineoplastic agent;
plant metabolite
picumast[no description available]medium10
prenylamine lactate[no description available]medium20
aminopterin[no description available]medium10dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen
nitrites[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
trimethyloxamine[no description available]medium10tertiary amine oxideEscherichia coli metabolite;
metabolite;
osmolyte
2-aminoisobutyric acid[no description available]medium102,2-dialkylglycine zwitterion;
2,2-dialkylglycine
n-(8-aminohexyl)-5-iodonaphthalene-1-sulfonamide[no description available]medium20
trinitrobenzenesulfonic acid[no description available]medium10arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
kynurenic acid[no description available]medium10monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
elastin[no description available]medium30oligopeptide
acetylglucosamine[no description available]medium10N-acetyl-D-glucosamineepitope
asparagine[no description available]medium20amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
4-bromo-a-23187[no description available]medium10
s-adenosylhomocysteine[no description available]medium10adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide		cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite
mezerein[no description available]medium30diterpenoid
tolfenamic acid[no description available]medium10aminobenzoic acid;
organochlorine compound;
secondary amino compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
anthralin[no description available]medium10anthracenesantipsoriatic
ud cg 212 cl[no description available]medium10
idazoxan[no description available]medium20benzodioxine;
imidazolines		alpha-adrenergic antagonist
spiroxatrine[no description available]medium10imidazolidines
bmy 7378[no description available]medium10
androstenedione[no description available]medium2017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
c-peptide[no description available]medium10
buserelin[no description available]medium10oligopeptide
thromboplastin[no description available]medium10
neurotensin[no description available]medium30peptide hormonehuman metabolite;
mitogen;
neurotransmitter;
vulnerary
tamoxifen aziridine[no description available]medium10
3-nitrophenol[no description available]medium103-nitrophenols
triphenylphosphine[no description available]medium10benzenes;
tertiary phosphine		NMR chemical shift reference compound;
reducing agent
quin2[no description available]medium50
ha 1004[no description available]medium10isoquinolines
lignans[no description available]medium20
2,3-dibenzylbutane-1,4-diol[no description available]medium10
adenosine diphosphate ribose[no description available]medium20ADP-sugarEscherichia coli metabolite;
mouse metabolite
gamma-linolenic acid[no description available]medium10linolenic acid;
omega-6 fatty acid		human metabolite;
mouse metabolite;
plant metabolite
pyrophosphate[no description available]medium20diphosphate ion
carboprostacyclin[no description available]medium10prostanoid
bamipine[no description available]medium10aromatic amine
chlorphenoxamine[no description available]medium10diarylmethaneanticoronaviral agent
daurisoline[no description available]medium10isoquinolines
dequalinium[no description available]medium10quinolinium ionantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor
methionine sulfoximine[no description available]medium20methionine derivative;
non-proteinogenic alpha-amino acid;
sulfoximide
buthionine sulfoximine[no description available]medium10diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
mannosamine[no description available]medium10D-mannosamine
p-chloromercuribenzoic acid[no description available]medium10chlorine molecular entity;
mercuribenzoic acid
n-methylscopolamine[no description available]medium10
isoxazoles[no description available]medium10isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
alpha-aminopyridine[no description available]medium20
25-hydroxycholesterol[no description available]medium2025-hydroxy steroid;
oxysterol		human metabolite
acetic acid[no description available]medium20monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
mevalonic acid[no description available]medium103,5-dihydroxy-3-methylpentanoic acid
mevalonolactone[no description available]medium104-hydroxy-4-methyloxan-2-onefungal metabolite;
plant metabolite
6-deoxyglucose[no description available]medium10quinovose
cgp 28392[no description available]medium10aromatic ether
adenosine-5'-(n-ethylcarboxamide)[no description available]medium20adenosines;
monocarboxylic acid amide		adenosine A1 receptor agonist;
adenosine A2A receptor agonist;
antineoplastic agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
9-(2-hydroxy-3-nonyl)adenine[no description available]medium10
3,4,5-trimethoxybenzoic acid[no description available]medium10benzoic acids;
methoxybenzenes		human urinary metabolite;
human xenobiotic metabolite;
plant metabolite
metofenazate[no description available]medium30N-alkylpiperazine;
organochlorine compound;
phenothiazines
2',7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester[no description available]medium10
fibrin[no description available]medium20peptide
lithium carbonate[no description available]medium20carbonate salt;
lithium salt		antimanic drug
acetaldehyde[no description available]medium10aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
5-dimethylamiloride[no description available]medium10
thromboxane a2[no description available]medium10epoxy monocarboxylic acid;
thromboxanes A		mouse metabolite
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid[no description available]medium20
bathophenanthroline[no description available]medium20benzenes;
phenanthrolines		chelator
1,7-phenanthroline[no description available]medium30phenanthroline
tosylphenylalanyl chloromethyl ketone[no description available]medium20alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor
inositol-1,3,4,5-tetrakisphosphate[no description available]medium10inositol phosphate
methaqualone[no description available]medium20quinazolinesGABA agonist;
sedative
mersalyl[no description available]medium10
dimethylphenylpiperazinium iodide[no description available]medium20N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
centbutindole[no description available]medium11beta-carbolines
pyrazines[no description available]medium11diazine;
pyrazines		Daphnia magna metabolite
chlorine[no description available]medium20diatomic chlorine;
gas molecular entity		bleaching agent
potassium cyanide[no description available]medium30cyanide salt;
one-carbon compound;
potassium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
neurotoxin
triethanolamine[no description available]medium10amino alcohol;
tertiary amino compound;
triol		buffer;
surfactant
pk 11195[no description available]medium10aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent
eicosapentaenoic acid[no description available]medium10icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical
bw-755c[no description available]medium40
cd 349[no description available]medium10
cobrotoxin[no description available]medium10
alpha-cobratoxin[no description available]medium10
lutetium[no description available]medium10d-block element atom;
lanthanoid atom
terbium[no description available]medium10f-block element atom;
lanthanoid atom
12-o-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate[no description available]medium10
ceruletide[no description available]medium10oligopeptidediagnostic agent;
gastrointestinal drug
chlordiazepoxide, clidinium drug combination[no description available]medium10
quinuclidines[no description available]medium10quinuclidines;
saturated organic heterobicyclic parent
technetium tc 99m medronate[no description available]medium10
flupenthixol decanoate[no description available]medium10
lisuride[no description available]medium10monocarboxylic acid amideantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
serotonergic agonist
benzofurans[no description available]medium20
bis(1,3-diethylthiobarbiturate)trimethineoxonol[no description available]medium10
n-benzyladriamycin-14-valerate[no description available]medium10
nogalamycin[no description available]medium10
menogaril[no description available]medium10
n,n-dibenzyldaunorubicin[no description available]medium10
beta-endorphin[no description available]medium10
chitosan[no description available]medium10
fenclonine[no description available]medium20phenylalanine derivative
tempocholine[no description available]medium10
bromide[no description available]medium10halide anion;
monoatomic bromine
triiodothyronine, reverse[no description available]medium103,3',5'-triiodothyronine;
amino acid zwitterion
tosyllysine chloromethyl ketone[no description available]medium20sulfonic acid derivative
tosylarginine methyl ester[no description available]medium20guanidines;
L-arginine ester;
methyl ester;
sulfonamide
retinaldehyde[no description available]medium10retinal;
vitamin A		gap junctional intercellular communication inhibitor;
human metabolite;
mouse metabolite
dolichols[no description available]medium10polyterpene
dehydroepiandrosterone sulfate[no description available]medium1017-oxo steroid;
steroid sulfate		EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite;
mouse metabolite
ecdysone[no description available]medium1014alpha-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
6-oxo steroid;
ecdysteroid		prohormone
pyocyanine[no description available]medium10iminium betaine;
phenazines		antibacterial agent;
bacterial metabolite;
biological pigment;
virulence factor
taurochenodeoxycholic acid[no description available]medium10bile acid taurine conjugatehuman metabolite;
mouse metabolite
propentofylline[no description available]medium10oxopurine
antimony[no description available]medium10metalloid atom;
pnictogen
pyroantimonate[no description available]medium10
cdp ethanolamine[no description available]medium10nucleotide-(amino alcohol)s;
phosphoethanolamine		mouse metabolite
cytidine diphosphate[no description available]medium10cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite
quin2-acetoxymethyl ester[no description available]medium10
lhrh, gln(8)-[no description available]medium10
iodine[no description available]medium40halide anion;
monoatomic iodine		human metabolite
1,6-bis(cyclohexyloximinocarbonyl)hexane[no description available]medium10carbamate ester;
organonitrogen compound
phenylalanine[no description available]medium40amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
3-o-methylglucose[no description available]medium10D-aldohexose derivative
preproenkephalin[no description available]medium10
galactose[no description available]medium10
ouabagenin[no description available]medium101-hydroxy steroid;
11alpha-hydroxy steroid;
14beta-hydroxy steroid;
19-hydroxy steroid;
3beta-hydroxy steroid;
5beta-hydroxy steroid		EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene[no description available]medium10
cortodoxone[no description available]medium10deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
triamcinolone acetonide[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
neuropeptide y[no description available]medium10
motilin[no description available]medium10
losartan potassium[no description available]medium10
nimustine[no description available]medium30aminopyrimidine;
N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
anisomycin[no description available]medium10monohydroxypyrrolidine;
organonitrogen heterocyclic antibiotic		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
DNA synthesis inhibitor;
protein synthesis inhibitor
oxazolone[no description available]medium10
clorgyline[no description available]medium10aromatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound		antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor
triphenylethylene[no description available]medium10stilbenoid
stilbenes[no description available]medium10stilbene
sodium dodecyl sulfate[no description available]medium10organic sodium saltdetergent;
protein denaturant
4-toluidine[no description available]medium10aminotoluene
4-nitrophenylphosphate[no description available]medium10aryl phosphatemouse metabolite
cyclosporin d[no description available]medium10
cyclosporin h[no description available]medium10
alpha,beta-methyleneadenosine 5'-triphosphate[no description available]medium10nucleoside triphosphate analogue
5'-adenylyl (beta,gamma-methylene)diphosphonate[no description available]medium10nucleoside triphosphate analogue
valrubicin[no description available]medium20anthracycline;
trifluoroacetamide
ginkgolide b[no description available]medium10
molybdenum[no description available]medium10chromium group element atommicronutrient
molybdate ion[no description available]medium10divalent inorganic anion;
molybdenum oxoanion		Escherichia coli metabolite
1-ethyl-2-pyrrolidinylmethyl-alpha-phenylcyclopentylglycolate, 1-ethyl-3-piperidyl-alpha-phenylcyclopentylglycolate drug combination[no description available]medium10
fluorocitrate[no description available]medium10carbonyl compound
5-hydroxy-6,8,11,14-eicosatetraenoic acid[no description available]medium10HETEhuman metabolite;
mouse metabolite
methylglucoside[no description available]medium10
veratrine[no description available]medium10alkaloid
octopamine[no description available]medium10phenylethanolamines;
tyramines		neurotransmitter
pirarubicin[no description available]medium10anthracycline
acrylamide[no description available]medium10acrylamides;
N-acylammonia;
primary carboxamide		alkylating agent;
carcinogenic agent;
Maillard reaction product;
mutagen;
neurotoxin
pyrimidine dimers[no description available]medium10
strophanthidin[no description available]medium1014beta-hydroxy steroid;
19-oxo steroid;
3beta-hydroxy steroid;
5beta-hydroxy steroid;
cardenolides;
steroid aldehyde
hexacyanoferrate iii[no description available]medium10
dihydrocytochalasin b[no description available]medium10
azepexole[no description available]medium10
barbituric acid[no description available]medium10barbituratesallergen;
xenobiotic
pyridoxal phosphate[no description available]medium20methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phlorhizin[no description available]medium10aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		antioxidant;
plant metabolite
n,n-dimethyltryptamine[no description available]medium10tryptamine alkaloid;
tryptamines
fumarates[no description available]medium21butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
nikethamide[no description available]medium10pyridinecarboxamide
bemegride[no description available]medium20piperidones
tremorine[no description available]medium30N-alkylpyrrolidine
lobeline[no description available]medium10
paraoxon[no description available]medium20aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
chlormadinone acetate[no description available]medium10corticosteroid hormone
pentaerythritol tetranitrate[no description available]medium30pentaerythritol nitrateexplosive;
vasodilator agent
paraldehyde[no description available]medium20trioxanesedative
firefly luciferin[no description available]medium101,3-thiazolemonocarboxylic acid;
benzothiazoles;
imidothioate		luciferin
meclofenoxate[no description available]medium20monocarboxylic acid
sulfites[no description available]medium10divalent inorganic anion;
sulfur oxide;
sulfur oxoanion
2-piperidone[no description available]medium10delta-lactam;
piperidones		EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor
nandrolone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid		human metabolite
chlormethiazole[no description available]medium20thiazoles
morphinans[no description available]medium10isoquinoline alkaloid fundamental parent;
morphinane alkaloid
acid phosphatase[no description available]medium20
chloral hydrate[no description available]medium10aldehyde hydrate;
ethanediol;
organochlorine compound		general anaesthetic;
mouse metabolite;
sedative;
xenobiotic
orotic acid[no description available]medium10pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
pentazocine[no description available]medium10benzazocine
heroin[no description available]medium10morphinane alkaloidmu-opioid receptor agonist;
opioid analgesic;
prodrug
benperidol[no description available]medium30aromatic ketone
chlorisondamine[no description available]medium10isoindoles
vitamin b 12[no description available]medium10
carbonates[no description available]medium10carbon oxoanion
deuterium[no description available]medium10dihydrogen
methylene blue[no description available]medium10organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
carbamates[no description available]medium10amino-acid anion
chloralose[no description available]medium10
sodium hydroxide[no description available]medium10alkali metal hydroxide
psilocybin[no description available]medium10organic phosphate;
tertiary amino compound;
tryptamine alkaloid		fungal metabolite;
hallucinogen;
prodrug;
serotonergic agonist
mescaline[no description available]medium10methoxybenzenes;
phenethylamine alkaloid;
primary amino compound		hallucinogen
sabinene[no description available]medium20thujeneplant metabolite
eye[no description available]medium41
exudates[no description available]medium20
fomesafen[no description available]medium131aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
4-methoxyamphetamine[no description available]medium10
ego[no description available]medium11
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone[no description available]medium50dichlorobenzene;
differentiation-inducing factor;
monomethoxybenzene;
resorcinols		eukaryotic metabolite;
signalling molecule
isomethyleugenol[no description available]medium70isomethyleugenol
torpedo[no description available]medium50
khellin[no description available]medium10furanochromone;
organic heterotricyclic compound;
oxacycle		anti-asthmatic agent;
bronchodilator agent;
cardiovascular drug;
vasodilator agent
3,4-methylenedioxyamphetamine[no description available]medium10benzodioxoles
apnea[no description available]medium10purine nucleoside
humulene[no description available]medium21alpha-humulene
propiomazine[no description available]medium00aromatic ketone;
phenothiazines;
tertiary amino compound		dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
sedative;
serotonergic antagonist
thiopropazate[no description available]medium00acetate ester;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		dopaminergic antagonist;
phenothiazine antipsychotic drug
methiothepin[no description available]medium00aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist
7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol[no description available]low00benzazepine;
organochlorine compound;
tertiary amino compound		dopaminergic antagonist
azaperone[no description available]medium00aminopyridine;
aromatic ketone;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist
butaclamol[no description available]low00amino alcohol;
organic heteropentacyclic compound;
tertiary alcohol;
tertiary amino compound		dopaminergic antagonist
spiramide[no description available]medium00aromatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
serotonergic antagonist
tetrahydropalmatine[no description available]low00an (S)-7,8,13,14-tetrahydroprotoberberine;
berberine alkaloid;
organic heterotetracyclic compound		adrenergic agent;
dopaminergic antagonist;
non-narcotic analgesic
aj 76[no description available]low00secondary amino compound;
tetralins		dopaminergic antagonist
lurasidone[no description available]low001,2-benzisothiazole;
bridged compound;
dicarboximide;
N-arylpiperazine		adrenergic antagonist;
dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
nafadotride[no description available]low00aromatic ether;
naphthalenecarboxamide;
nitrile;
pyrrolidines;
tertiary amino compound		dopaminergic antagonist
lurasidone hydrochloride[no description available]low00hydrochlorideadrenergic antagonist;
dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
pipamperone dihydrochloride[no description available]low00hydrochloridedopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
buclizine[no description available]medium00monochlorobenzenes;
N-alkylpiperazine		antiemetic;
central nervous system depressant;
cholinergic antagonist;
histamine antagonist;
local anaesthetic
zingerone[no description available]low00methyl ketone;
monomethoxybenzene;
phenols		anti-inflammatory agent;
antiemetic;
antioxidant;
flavouring agent;
fragrance;
plant metabolite;
radiation protective agent
alosetron hydrochloride[no description available]low00hydrochlorideantiemetic;
serotonergic antagonist
fk 1052[no description available]low00imidazoles;
organic heterotricyclic compound		antiemetic;
serotonergic antagonist
pachypodol[no description available]low00dihydroxyflavone;
trimethoxyflavone		antiemetic;
plant metabolite
cyclizine hydrochloride[no description available]low00hydrochlorideantiemetic;
central nervous system depressant;
cholinergic antagonist;
H1-receptor antagonist
netupitant[no description available]medium00aminopyridine;
monocarboxylic acid amide;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
toluenes		antiemetic;
neurokinin-1 receptor antagonist
rs 25259-197[no description available]low00hydrochlorideantiemetic;
serotonergic antagonist
rolapitant[no description available]medium00azaspiro compound;
ether;
organofluorine compound;
piperidines;
pyrrolidin-2-ones		antiemetic;
neurokinin-1 receptor antagonist
cupric chloride[no description available]low00copper molecular entity;
inorganic chloride		EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
loceryl[no description available]low00morpholine antifungal drug;
tertiary amino compound		EC 1.14.13.132 (squalene monooxygenase) inhibitor;
EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
fonazine[no description available]low00phenothiazines
mequitazine[no description available]low00phenothiazines
metiazinic acid[no description available]low00phenothiazinesdrug allergen;
non-steroidal anti-inflammatory drug
thiazinamium[no description available]low00phenothiazines
pyrathiazine[no description available]low00phenothiazines
oxomemazine[no description available]low00phenothiazines
piperacetazine[no description available]low00phenothiazines
metopimazine[no description available]low00phenothiazines
sulforidazine[no description available]low00phenothiazines
pipothiazine palmitate[no description available]low00phenothiazines
perphenazine decanoate[no description available]low00phenothiazines
promethazine sulfoxide[no description available]low00phenothiazines
fluphenazine hydrochloride[no description available]low00phenothiazinesanticoronaviral agent
fenethazine[no description available]low00phenothiazines
10H-phenothiazine 5-oxide[no description available]low00phenothiazines
n-methylphenothiazine[no description available]low00phenothiazines
fenoverine[no description available]low00phenothiazines
1-(10-methyl-2-phenothiazinyl)ethanone[no description available]low00phenothiazines
thioproperazine mesylate[no description available]low00phenothiazines
ethacizine[no description available]low00phenothiazines
sk&f 7172-a2[no description available]low00phenothiazines
hydromethylthionine[no description available]low00aromatic amine;
phenothiazines;
tertiary amino compound		bacterial xenobiotic metabolite;
fluorochrome;
mouse metabolite;
rat metabolite
3-[4-(2-hydroxyethyl)-1-piperazinyl]-1-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanone[no description available]low00phenothiazines
chlorpromazine n-oxide[no description available]low00organochlorine compound;
phenothiazines;
tertiary amine oxide		metabolite
10-methyl-3-phenothiazinamine[no description available]low00phenothiazines
1-(2-chloro-10-phenothiazinyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanone[no description available]low00phenothiazines
darunavir ethanolate[no description available]low00phenothiazines
1-(1-benzotriazolyl)-3-(10-phenothiazinyl)-2-propanol[no description available]low00phenothiazines
2-chloro-N-[1-[oxo(10-phenothiazinyl)methyl]-4-piperidinyl]benzamide[no description available]low00phenothiazines
(4-methylphenyl)-(10-phenothiazinyl)methanone[no description available]low00phenothiazines
methotrimeprazine sulfoxide[no description available]low00phenothiazines
benefin[no description available]low00C-nitro compound;
organofluorine compound;
substituted aniline;
tertiary amino compound		agrochemical;
herbicide
cgs 12066[no description available]low00N-arylpiperazine;
organofluorine compound;
pyrroloquinoxaline		serotonergic agonist
fludiazepam[no description available]low001,4-benzodiazepinone;
organochlorine compound;
organofluorine compound		anxiolytic drug
flumequine[no description available]low003-oxo monocarboxylic acid;
organofluorine compound;
pyridoquinoline;
quinolone antibiotic
vanoxerine[no description available]low00ether;
N-alkylpiperazine;
organofluorine compound;
tertiary amino compound		dopamine uptake inhibitor
sb 220025[no description available]low00aminopyrimidine;
imidazoles;
organofluorine compound;
piperidines		angiogenesis inhibitor;
anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
fluoroacetic acid[no description available]low00haloacetic acid;
organofluorine compound		EC 4.2.1.3 (aconitate hydratase) inhibitor
tosufloxacin[no description available]low001,8-naphthyridine derivative;
amino acid;
aminopyrrolidine;
monocarboxylic acid;
organofluorine compound;
primary amino compound;
quinolone antibiotic;
tertiary amino compound
zardaverine[no description available]low00organofluorine compound;
pyridazinone		anti-asthmatic drug;
bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
peripheral nervous system drug
1,1-difluoroethylene[no description available]low00olefinic compound;
organofluorine compound
chloropentafluoroethane[no description available]low00organochlorine compound;
organofluorine compound
2-fluoroadenosine[no description available]low00adenosines;
organofluorine compound
perfluorotributylamine[no description available]low00organofluorine compoundblood substitute;
greenhouse gas;
solvent
5-fluorouridine[no description available]low00organofluorine compound;
uridines		mutagen
5-fluorotryptophan[no description available]low00non-proteinogenic alpha-amino acid;
organofluorine compound;
tryptophan derivative
bromochlorodifluoromethane[no description available]low00one-carbon compound;
organobromine compound;
organochlorine compound;
organofluorine compound
difluoroacetic acid[no description available]low00monocarboxylic acid;
organofluorine compound
fluroxene[no description available]low00organofluorine compound
2,3,4,5,6-pentafluorobenzyl alcohol[no description available]low00benzyl alcohols;
organofluorine compound
2-fluoroadenine[no description available]low00organofluorine compound;
purines		antineoplastic agent
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide[no description available]low00organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides		antifungal agrochemical;
genotoxin
dichlofluanid[no description available]low00organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides		acaricide;
antifungal agrochemical
5-fluorocytidine[no description available]low00cytidines;
organofluorine compound
doxifluridine[no description available]low00organofluorine compound;
pyrimidine 5'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
prodrug
flubendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound		antinematodal drug;
teratogenic agent
flunixin[no description available]low00aminopyridine;
organofluorine compound;
pyridinemonocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
acifluorfen[no description available]low00aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
triflumuron[no description available]low00aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid[no description available]low00aminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		environmental contaminant;
herbicide;
xenobiotic
haloxyfop[no description available]low00aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines
fluazifop-butyl[no description available]low00aromatic ether;
carboxylic ester;
organofluorine compound;
pyridines
gemcitabine hydrochloride[no description available]low00hydrochloride;
organofluorine compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral drug;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
immunosuppressive agent;
radiosensitizing agent
4-fluorofentanyl[no description available]low00monocarboxylic acid amide;
organofluorine compound;
piperidines
heptafluorobutyric anhydride[no description available]low00acyclic carboxylic anhydride;
organofluorine compound		chromatographic reagent
perfluorotripropylamine[no description available]low00organofluorine compoundblood substitute
3-fluoropyruvate[no description available]low002-oxo monocarboxylic acid;
organofluorine compound
halopropane[no description available]low00organofluorine compound
flurithromycin[no description available]low00cyclic ketone;
erythromycin derivative;
organofluorine compound;
semisynthetic derivative		antibacterial drug
fluphenacur[no description available]low00aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound
nucleocidin[no description available]low006-aminopurines;
adenosines;
diol;
organofluorine compound;
sulfamate ester		antibacterial agent;
bacterial metabolite;
nucleoside antibiotic;
protein synthesis inhibitor;
trypanocidal drug
fluoroacetaldehyde[no description available]low00aldehyde;
organofluorine compound		cardiotoxic agent
fc 75[no description available]low00alkyltetrahydrofuran;
organofluorine compound
tetraconazole[no description available]low00dichlorobenzene;
ether;
organofluorine compound;
triazoles
hei 712[no description available]low00organofluorine compound;
quinolone
n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide[no description available]low00dichlorobenzene;
organofluorine compound;
sulfonamide;
triazoles		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
thifluzamide[no description available]low001,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
fludioxonil[no description available]low00benzodioxoles;
nitrile;
organofluorine compound;
pyrroles		androgen antagonist;
antifungal agrochemical;
estrogen receptor agonist
fluquinconazole[no description available]low00conazole fungicide;
dichlorobenzene;
organofluorine compound;
quinazolines;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
cloransulam-methyl[no description available]low00methyl ester;
monochlorobenzenes;
organofluorine compound;
sulfonamide;
triazolopyrimidines		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
fluazifop[no description available]low00aromatic ether;
monocarboxylic acid;
organofluorine compound;
pyridines
dithiopyr[no description available]low00organofluorine compound;
pyridines;
thioester
s 53482[no description available]low00benzoxazine;
dicarboximide;
organofluorine compound;
terminal acetylenic compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide;
teratogenic agent
clodinafop-propargyl[no description available]low00aromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines		agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide
triflusulfuron-methyl[no description available]low001,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide
novaluron[no description available]low00aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound
cyfluthrin[no description available]low00aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester insecticide
fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether[no description available]low00organofluorine compound
florfenicol[no description available]low00organochlorine compound;
organofluorine compound;
secondary alcohol;
secondary carboxamide;
sulfone		antimicrobial agent
sc 58125[no description available]low00organofluorine compound;
pyrazoles;
sulfone		antineoplastic agent;
cyclooxygenase 2 inhibitor
5-fluoromethylornithine[no description available]low00organofluorine compound;
ornithine derivative		EC 2.6.1.13 (ornithine aminotransferase) inhibitor
nitroflurbiprofen[no description available]low00biphenyls;
carboxylic ester;
nitrate ester;
organofluorine compound		cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector;
non-steroidal anti-inflammatory drug;
vasodilator agent
ezogabine[no description available]low00carbamate ester;
organofluorine compound;
secondary amino compound;
substituted aniline		anticonvulsant;
potassium channel modulator
garenoxacin[no description available]low00aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
non-steroidal anti-inflammatory drug
5-fluorowillardiine[no description available]low00L-alanine derivative;
non-proteinogenic L-alpha-amino acid;
organofluorine compound		AMPA receptor agonist
perfluoro-n-methyldecahydroisoquinoline[no description available]low00organofluorine compoundblood substitute
fc 80[no description available]low00alkyltetrahydrofuran;
organofluorine compound
5-fluorouridine 5'-phosphate[no description available]low00organofluorine compound;
pyrimidine ribonucleoside 5'-monophosphate		drug metabolite
canertinib[no description available]low00monochlorobenzenes;
morpholines;
organofluorine compound;
quinazolines		antineoplastic agent;
tyrosine kinase inhibitor
jte 522[no description available]low001,3-oxazoles;
organofluorine compound;
sulfonamide		cyclooxygenase 2 inhibitor
trifluoromethionine[no description available]low00L-methionine derivative;
non-proteinogenic L-alpha-amino acid;
organofluorine compound
cimicoxib[no description available]low00aromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
diflomotecan[no description available]low00epsilon-lactone;
organic heteropentacyclic compound;
organofluorine compound;
organonitrogen heterocyclic compound;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor
5',5',5'-trifluoroleucine[no description available]low00leucine derivative;
non-proteinogenic alpha-amino acid;
organofluorine compound
sorbinil[no description available]low00azaspiro compound;
chromanes;
imidazolidinone;
organofluorine compound;
oxaspiro compound		antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor
2'-deoxy-2-fluoroadenosine[no description available]low00adenosines;
organofluorine compound
8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-yn-1-yl-9H-purin-6-amine[no description available]low006-aminopurines;
acetylenic compound;
methoxybenzenes;
monochlorobenzenes;
organofluorine compound		antineoplastic agent;
Hsp90 inhibitor
efinaconazole[no description available]low00conazole antifungal drug;
olefinic compound;
organofluorine compound;
piperidines;
tertiary alcohol;
tertiary amino compound;
triazole antifungal drug		EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
favipiravir[no description available]low00hydroxypyrazine;
organofluorine compound;
primary carboxamide		anticoronaviral agent;
antiviral drug;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
ck-0944666[no description available]low00benzamides;
indoles;
organofluorine compound		actin polymerisation inhibitor
2-(3-Chloro-2-fluorophenyl)-2,3-dihydroisothiazol-3-one[no description available]low00organofluorine compound
4-[(3-fluorophenyl)methyl-(3-pyridinylmethyl)amino]-4-oxobutanoic acid[no description available]low00organofluorine compound
transfluthrin[no description available]low00carboxylic ester;
cyclopropanes;
organochlorine compound;
organofluorine compound		pyrethroid ester insecticide
4-(4-fluorophenyl)-3H-thiazole-2-thione[no description available]low00organofluorine compound
2-(4-chlorophenyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole[no description available]low00organofluorine compound
N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide[no description available]low00organofluorine compound
1-(cycloheptylideneamino)-3-(4-fluorophenyl)thiourea[no description available]low00organofluorine compound
2-(2-fluorophenyl)-5-phenyl-4-thieno[2,3-d][1,3]oxazinone[no description available]low00organofluorine compound
N-cyano-N'-(2-fluorophenyl)carbamimidothioic acid [2-(tert-butylamino)-2-oxoethyl] ester[no description available]low00organofluorine compound
N-(4-fluorobenzyl)urea[no description available]low00organofluorine compound
N1-(3-chloro-4-fluorophenyl)-2-(methylthio)acetamide[no description available]low00organofluorine compound
ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate[no description available]low00ethyl ester;
monochlorobenzenes;
organofluorine compound;
pyrazoles;
sulfonamide
S-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl] 5-(phenylethynyl)furan-2-carbothioate[no description available]low00acetylenic compound;
furans;
organofluorine compound;
thioester;
triazoles
4-[1-(4-fluorophenyl)ethyl]-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione[no description available]low00organofluorine compound
1-(4-fluorophenyl)-1-cyclopentanecarboxylic acid [2-(2,6-dimethyl-4-morpholinyl)-2-oxoethyl] ester[no description available]low00organofluorine compound
zd 6474[no description available]low00aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine		antineoplastic agent;
tyrosine kinase inhibitor
6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline[no description available]low00organic heterotricyclic compound;
organofluorine compound;
pyridines;
secondary amino compound
1-(4-fluorophenyl)-N-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carbothioamide[no description available]low00organofluorine compound
2-[[2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]thio]acetic acid butyl ester[no description available]low00organofluorine compound
sc 560[no description available]low00aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug
1-[(2-fluorophenyl)methyl]-4-pyrazolamine[no description available]low00organofluorine compound
3-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethyl]-1,1-bis(phenylmethyl)urea[no description available]low00organofluorine compound
ro 60-0175[no description available]low00indoles;
organochlorine compound;
organofluorine compound;
primary amino compound
arachidonyltrifluoromethane[no description available]low00fatty acid derivative;
ketone;
olefinic compound;
organofluorine compound		EC 3.1.1.4 (phospholipase A2) inhibitor
cyhalothrin[no description available]low00aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
sulindac sulfide[no description available]low00aryl sulfide;
monocarboxylic acid;
organofluorine compound		antineoplastic agent;
apoptosis inducer;
non-steroidal anti-inflammatory drug
bw b70c[no description available]low00aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
sulindac sulfone[no description available]low00monocarboxylic acid;
organofluorine compound;
sulfone		apoptosis inducer;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
clodinafop[no description available]low00aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines		EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
phenoxy herbicide
2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one[no description available]low00organic heterotetracyclic compound;
organofluorine compound		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
z-val-ala-asp(ome)-fluoromethylketone[no description available]low00carbamate ester;
organofluorine compound;
tripeptide		apoptosis inhibitor;
protease inhibitor
robenacoxib[no description available]low00aromatic amino acid;
monocarboxylic acid;
organofluorine compound;
phenylacetic acids;
secondary amino compound		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
acrinathrin[no description available]low00cyclopropanecarboxylate ester;
organofluorine compound		pyrethroid ester acaricide;
pyrethroid ester insecticide
bifenthrin[no description available]low00carboxylic ester;
cyclopropanecarboxylate ester;
cyclopropanes;
organochlorine compound;
organofluorine compound		pyrethroid ester acaricide;
pyrethroid ester insecticide
flibanserin[no description available]low00benzimidazoles;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound		antidepressant;
serotonergic agonist;
serotonergic antagonist
ru 58668[no description available]low0017beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
organofluorine compound;
sulfone		anti-estrogen;
antineoplastic agent;
estrogen receptor antagonist
nepicastat[no description available]low001,3-dihydroimidazole-2-thiones;
organofluorine compound;
primary amino compound;
tetralins		EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor
gw 501516[no description available]low001,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound		carcinogenic agent;
PPARbeta/delta agonist
noviflumuron[no description available]low00aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound
flonicamid[no description available]low00nitrile;
organofluorine compound;
pyridinecarboxamide		environmental contaminant;
insecticide;
xenobiotic
4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide[no description available]low00organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
tafluprost[no description available]low00isopropyl ester;
organofluorine compound;
prostaglandins Falpha		prostaglandin receptor agonist
ticagrelor[no description available]low00aryl sulfide;
hydroxyether;
organofluorine compound;
secondary amino compound;
triazolopyrimidines		P2Y12 receptor antagonist;
platelet aggregation inhibitor
am 694[no description available]low00aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid		cannabinoid receptor agonist
NNC 55-0396 (free base)[no description available]low00benzimidazoles;
cyclopropanecarboxylate ester;
organofluorine compound;
tertiary amino compound;
tetralins		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
neuroprotective agent;
potassium channel blocker;
T-type calcium channel blocker
osu 03012[no description available]low00antibiotic antifungal drug;
aromatic amide;
glycine derivative;
organofluorine compound;
phenanthrenes;
pyrazoles		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
vorapaxar[no description available]low00carbamate ester;
lactone;
naphthofuran;
organofluorine compound;
pyridines		cardiovascular drug;
platelet aggregation inhibitor;
protease-activated receptor-1 antagonist
bibw 2992[no description available]low00aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
tyrosine kinase inhibitor
r-138727[no description available]low00organofluorine compound
fluoxastrobin[no description available]low00aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
flumorph[no description available]low00aromatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide
fluopicolide[no description available]low00benzamide fungicide;
benzamides;
dichlorobenzene;
monochloropyridine;
organofluorine compound		antifungal agrochemical
gamendazole[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
dichlorobenzene;
indazoles;
olefinic compound;
organofluorine compound		antispermatogenic agent;
eukaryotic translation elongation factor 1alpha 1 inhibitor;
Hsp90 inhibitor;
synthetic oral contraceptive
tedizolid[no description available]low00carbamate ester;
organofluorine compound;
oxazolidinone;
primary alcohol;
pyridines;
tetrazoles		antimicrobial agent;
drug metabolite;
protein synthesis inhibitor
rx-3117[no description available]low00organofluorine compound;
primary allylic alcohol;
triol		antimetabolite;
antineoplastic agent;
apoptosis inducer;
DNA synthesis inhibitor;
prodrug
picoxystrobin[no description available]low00aromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
bay 63-2521[no description available]low00aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine		antihypertensive agent;
soluble guanylate cyclase activator
penthiopyrad[no description available]low00aromatic amide;
organofluorine compound;
pyrazoles;
thiophenes
tedizolid phosphate[no description available]low00carbamate ester;
organofluorine compound;
oxazolidinone;
phosphate monoester;
pyridines;
tetrazoles		antimicrobial agent;
prodrug;
protein synthesis inhibitor
tavaborole[no description available]low00benzoxaborole;
organofluorine compound		antifungal agent;
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor;
protein synthesis inhibitor
tembotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
finafloxacin[no description available]low00cyclopropanes;
monocarboxylic acid;
nitrile;
organofluorine compound;
quinolone;
secondary amino compound;
tertiary amino compound		antibacterial drug;
antimicrobial agent
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine[no description available]low00aminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate		antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
idelalisib[no description available]low00aromatic amine;
organofluorine compound;
purines;
quinazolines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
zstk474[no description available]low00benzimidazoles;
morpholines;
organofluorine compound;
triamino-1,3,5-triazine		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
trifloxystrobin[no description available]low00methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
organofluorine compound;
oxime O-ether		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide[no description available]low00aromatic amide;
organofluorine compound;
pyrazoles
n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide[no description available]low00aromatic amide;
cyclopropanes;
organofluorine compound;
pyrazoles;
ring assembly
butafenacil[no description available]low00benzoate ester;
diester;
monochlorobenzenes;
olefinic compound;
organofluorine compound		EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
bgt226[no description available]low00aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
buparlisib[no description available]low00aminopyridine;
aminopyrimidine;
morpholines;
organofluorine compound		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
lumacaftor[no description available]low00aromatic amide;
benzodioxoles;
benzoic acids;
cyclopropanes;
organofluorine compound;
pyridines		CFTR potentiator;
orphan drug
ro5126766[no description available]low00aryloxypyrimidine;
coumarins;
organofluorine compound;
pyridines;
sulfamides		antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sulfoxaflor[no description available]low00nitrile;
organofluorine compound;
pyridines;
sulfoximide
ph 797804[no description available]low00aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone		anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
lde225[no description available]low00aminopyridine;
aromatic ether;
benzamides;
biphenyls;
morpholines;
organofluorine compound;
tertiary amino compound		antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist
dafadine D[no description available]low00aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
organofluorine compound;
pyridines		P450 inhibitor
canagliflozin[no description available]low00C-glycosyl compound;
organofluorine compound;
thiophenes		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
florbetapir f 18[no description available]low00(18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline		radioactive imaging agent
navitoclax[no description available]low00aryl sulfide;
monochlorobenzenes;
morpholines;
N-sulfonylcarboxamide;
organofluorine compound;
piperazines;
secondary amino compound;
sulfone;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
dcc-2036[no description available]low00organofluorine compound;
phenylureas;
pyrazoles;
pyridinecarboxamide;
quinolines		tyrosine kinase inhibitor
cabozantinib[no description available]low00aromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines		antineoplastic agent;
tyrosine kinase inhibitor
pexidartinib[no description available]low00aminopyridine;
organochlorine compound;
organofluorine compound;
pyrrolopyridine;
secondary amino compound		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
TAK-580[no description available]low001,3-thiazolecarboxamide;
aminopyrimidine;
chloropyridine;
organofluorine compound;
pyrimidinecarboxamide;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor
dabrafenib[no description available]low001,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor
[5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid[no description available]low00organofluorine compoundnon-steroidal anti-inflammatory drug
torin 1[no description available]low00N-acylpiperazine;
N-arylpiperazine;
organofluorine compound;
pyridoquinoline;
quinolines		antineoplastic agent;
mTOR inhibitor
ro 4929097[no description available]low00dibenzoazepine;
dicarboxylic acid diamide;
lactam;
organofluorine compound		EC 3.4.23.46 (memapsin 2) inhibitor
torin 2[no description available]low00aminopyridine;
organofluorine compound;
primary amino compound;
pyridoquinoline		antineoplastic agent;
mTOR inhibitor
gsk2656157[no description available]low00biaryl;
indoles;
methylpyridines;
organofluorine compound;
pyrrolopyrimidine;
tertiary carboxamide		antineoplastic agent;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
PERK inhibitor
N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide[no description available]low00aromatic amide;
bridged compound;
olefinic compound;
organochlorine compound;
organofluorine compound;
pyrazoles
vericiguat[no description available]low00aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine		antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent
pacific blue succinimidyl ester[no description available]low00hydroxycoumarin;
N-hydroxysuccinimide ester;
organofluorine compound		fluorochrome
3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide[no description available]low00aromatic amide;
monocarboxylic acid amide;
organofluorine compound;
pyrazoles;
trichlorobenzene
oxathiapiprolin[no description available]low001,3-thiazoles;
isoxazoline;
N-acylpiperidine;
organofluorine compound;
pyrazoles;
tertiary carboxamide
5-[[5-(4-fluoro-2-hydroxyphenyl)-2-furanyl]methylidene]thiazolidine-2,4-dione[no description available]low00halophenol;
organofluorine compound
LimKi 3[no description available]low001,3-thiazoles;
dichlorobenzene;
organofluorine compound;
pyrazoles;
secondary carboxamide		LIM kinase inhibitor
ivosidenib[no description available]low00cyanopyridine;
monochlorobenzenes;
organofluorine compound;
pyrrolidin-2-ones;
secondary carboxamide;
tertiary carboxamide		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
praliciguat[no description available]low00aminopyrimidine;
isoxazoles;
monofluorobenzenes;
organofluorine compound;
pyrazoles;
secondary amino compound;
tertiary alcohol		anti-inflammatory agent;
antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent
MMP-9-IN-1[no description available]low00aromatic compound;
organic sulfide;
organofluorine compound;
pyrimidone;
secondary carboxamide		antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor
5-(2,5-difluorophenyl)-N-(2-oxolanylmethyl)-6H-1,3,4-thiadiazin-2-amine[no description available]low00organofluorine compound
nirmatrelvir[no description available]low00azabicyclohexane;
nitrile;
organofluorine compound;
pyrrolidin-2-ones;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
eprazinone[no description available]low00aromatic ketone;
ether;
N-alkylpiperazine		mucolytic
fleroxacin[no description available]low00difluorobenzene;
fluoroquinolone antibiotic;
monocarboxylic acid;
N-alkylpiperazine;
quinolines		antibacterial drug;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
gbr 12935[no description available]low00ether;
N-alkylpiperazine;
tertiary amino compound		dopamine uptake inhibitor
nan 190[no description available]low00N-alkylpiperazine;
N-arylpiperazine;
phthalimides		serotonergic antagonist
proglumetacin[no description available]low00aromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
n-methylquipazine[no description available]low00aminoquinoline;
N-alkylpiperazine;
N-arylpiperazine		serotonergic agonist
razoxane[no description available]low00N-alkylpiperazine
1-(3-chloro-5-benzo[b][1]benzoxepinyl)-4-methylpiperazine[no description available]low00N-alkylpiperazine;
organic heterotricyclic compound
triforine[no description available]low00amide fungicide;
formamides;
N-alkylpiperazine;
organochlorine compound		allergen;
antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
pefloxacin[no description available]low00fluoroquinolone antibiotic;
monocarboxylic acid;
N-alkylpiperazine;
N-arylpiperazine;
quinolone antibiotic;
quinolone		antibacterial drug;
antiinfective agent;
DNA synthesis inhibitor
dotarizine[no description available]low00cyclic ketal;
dioxolane;
N-alkylpiperazine		calcium channel blocker;
serotonergic antagonist;
vasodilator agent
difloxacin[no description available]low00fluoroquinolone antibiotic;
monocarboxylic acid;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
quinolone antibiotic;
quinolone		antibacterial drug;
Mycoplasma genitalium metabolite
amperozide[no description available]low00diarylmethane;
monofluorobenzenes;
N-alkylpiperazine;
secondary carboxamide;
ureas		anxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist
1-benzylpiperazine[no description available]low00N-alkylpiperazineenvironmental contaminant;
psychotropic drug;
serotonergic agonist;
xenobiotic
tandospirone[no description available]low00bridged compound;
dicarboximide;
N-alkylpiperazine;
N-arylpiperazine;
pyrimidines		antidepressant;
anxiolytic drug
gr 127935[no description available]low001,2,4-oxadiazole;
benzamides;
N-alkylpiperazine;
N-arylpiperazine
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine[no description available]low00(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist
brl 15572[no description available]low00monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist
vilazodone[no description available]low001-benzofurans;
indoles;
monocarboxylic acid amide;
N-alkylpiperazine;
N-arylpiperazine;
nitrile		antidepressant;
serotonergic agonist;
serotonin uptake inhibitor
scio-469[no description available]low00aromatic amide;
aromatic ketone;
chloroindole;
dicarboxylic acid diamide;
indolecarboxamide;
monofluorobenzenes;
N-acylpiperazine;
N-alkylpiperazine		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
masitinib[no description available]low001,3-thiazoles;
benzamides;
N-alkylpiperazine;
pyridines		antineoplastic agent;
antirheumatic drug;
tyrosine kinase inhibitor
sotrastaurin[no description available]low00indoles;
maleimides;
N-alkylpiperazine;
N-arylpiperazine;
quinazolines		anticoronaviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunosuppressive agent
erastin[no description available]low00aromatic ether;
diether;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
quinazolines;
tertiary carboxamide		antineoplastic agent;
ferroptosis inducer;
voltage-dependent anion channel inhibitor
at 13387[no description available]low00benzamides;
isoindoles;
N-alkylpiperazine;
resorcinols;
tertiary carboxamide		antineoplastic agent;
Hsp90 inhibitor
2-[4-(1,4-dithiepan-6-yl)-1-propan-2-yl-2-piperazinyl]ethanol[no description available]low00N-alkylpiperazine
tg101209[no description available]low00N-alkylpiperazine;
N-arylpiperazine;
pyrimidines;
secondary amino compound;
sulfonamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
lrrk2-in1[no description available]low00aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
ML-210[no description available]low00C-nitro compound;
diarylmethane;
isoxazoles;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
tertiary carboxamide		antineoplastic agent;
EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer;
prodrug
aripiprazole lauroxil[no description available]low00aromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone		H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist
abt-199[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea[no description available]low00aminopyrimidine;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
phenylureas		antineoplastic agent;
fibroblast growth factor receptor antagonist
gsk343[no description available]low00aminopyridine;
indazoles;
N-alkylpiperazine;
N-arylpiperazine;
pyridone;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
DDR1-IN-1[no description available]low00(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
hg-9-91-01[no description available]low00aminopyrimidine;
dimethoxybenzene;
N-alkylpiperazine;
N-arylpiperazine;
phenylureas;
secondary amino compound		antineoplastic agent;
salt-inducible kinase 2 inhibitor
mirodenafil[no description available]low00aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
hoe 33342[no description available]low00bibenzimidazole;
N-methylpiperazine		fluorochrome
bisbenzimidazole[no description available]low00bibenzimidazole;
N-methylpiperazine		anthelminthic drug;
fluorochrome
1-methylpiperazine[no description available]low00N-methylpiperazine
1,1-dimethyl-4-acetylpiperazinium[no description available]low00N-methylpiperazine
bosutinib[no description available]low00aminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound		antineoplastic agent;
tyrosine kinase inhibitor
amocarzine[no description available]low00C-nitro compound;
N-methylpiperazine;
secondary amino compound;
thioureas		antinematodal drug
azd2858[no description available]low00aromatic amine;
N-methylpiperazine;
pyrazines;
pyridines;
secondary carboxamide;
sulfonamide		antineoplastic agent;
bone density conservation agent;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
Wnt signalling activator
ponatinib[no description available]low00(trifluoromethyl)benzenes;
acetylenic compound;
benzamides;
imidazopyridazine;
N-methylpiperazine		antineoplastic agent;
tyrosine kinase inhibitor
asp3026[no description available]low00aromatic amine;
diamino-1,3,5-triazine;
monomethoxybenzene;
N-methylpiperazine;
piperidines;
secondary amino compound;
sulfone		antimalarial;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
entrectinib[no description available]low00benzamides;
difluorobenzene;
indazoles;
N-methylpiperazine;
oxanes;
secondary amino compound;
secondary carboxamide		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
gilteritinib[no description available]low00aromatic amine;
monomethoxybenzene;
N-methylpiperazine;
oxanes;
piperidines;
primary carboxamide;
pyrazines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
2019 Novel Coronavirus Disease0low10
2019 Novel Coronavirus Infection0low10
2019-nCoV Disease0low10
2019-nCoV Infection0low10
48,XXYY Syndrome0low10
49,XXXXY Syndrome0low10
A-V Dissociation0low10
Abdominal Epilepsy0low10
Abdominal Migraine0low20
Abnormal Movements0low10
Abnormalities, Autosome0low50
Abnormalities, Chromosomal0low50
Abnormalities, Chromosome0low50
Abnormalities, Congenital0low10
Abnormalities, Drug-Induced0low70
Abnormalities, Multiple0low10
Abnormalities, Musculoskeletal0low10
Abnormalities, Urogenital0low10
Abnormality, Heart0low20
Abscess, Amebic0low10
Absence Seizure0low90
Absence Seizures0low90
Academic Disorder, Developmental0low20
Acanthamebiasis0low10
Acanthamoeba Infection0low10
Acanthamoeba Meningoencephalitis0low10
Acantholysis Bullosa0low10
Acathisia, Drug-Induced0low20
Ache0low50
Acid Aspiration Syndrome0low10
Acidosis0low20
Acquired Immune Deficiency Syndrome0low10
Acquired Immuno-Deficiency Syndrome0low10
Acquired Immunodeficiency Syndrome0low10
Actinic Reticuloid Syndrome0low20
Action Tremor0medium61
Acute Brain Injuries0low20
Acute Confusional Migraine0low20
Acute Confusional Senile Dementia0low10
Acute Disease0medium238
Acute Edematous Pancreatitis0low20
Acute Kidney Failure0low20
Acute Kidney Injury0low20
Acute Kidney Insufficiency0low20
Acute Liver Injury, Drug-Induced0low160
Acute Myelogenous Leukemia0low20
Acute Myeloid Leukemia0low20
Acute Myeloid Leukemia with Maturation0low20
Acute Myeloid Leukemia without Maturation0low20
Acute Pancreatitis0low20
Acute Porphyria0low10
Acute Post-Traumatic Stress Disorder0low10
Acute Promyelocytic Leukemia0low10
Acute Renal Failure0low20
Acute Renal Injury0low20
Acute Renal Insufficiency0low20
Acute Rheumatic Fever0low10
Adam-Stokes Attacks0low10
Adams-Stokes Syndrome0low10
Adenocarcinoma0low80
Adenocarcinoma Of Kidney0low10
Adenocarcinoma of Lung0low20
Adenocarcinoma, Basal Cell0low80
Adenocarcinoma, Granular Cell0low80
Adenocarcinoma, Oxyphilic0low80
Adenocarcinoma, Renal0low10
Adenocarcinoma, Renal Cell0low10
Adenocarcinoma, Tubular0low80
Adenoma0low10
Adenoma Sebaceum0low10
Adenoma, Basal Cell0low10
Adenoma, beta-Cell0low60
Adenoma, Follicular0low10
Adenoma, Islet Cell0low80
Adenoma, Malignant0low80
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Trabecular0low10
Adjustment Disorder0low60
Adjustment Disorders0low60
Adolescent Gynecomastia0low10
Adrenal Cancer0low60
Adrenal Gland Cancer0low60
Adrenal Gland Hyperfunction0low10
Adrenal Gland Hypofunction0low20
Adrenal Gland Neoplasms0low60
Adrenal Hyperplasia, Congenital0low10
Adrenal Insufficiency0low20
Adrenal Neoplasm0low60
Adrenocortical Hyperfunction0low10
Adrenogenital Syndrome0low10
Adult Learning Disabilities0low20
Adult Learning Disorders0low20
Adverse Drug Event0low60
Adverse Drug Reaction0low60
Affective Disorders, Psychotic0low10
Affective Psychosis, Bipolar0medium352
African Lymphoma0low20
Age-Related Osteoporosis0low20
Aggression0medium171
Aging0low100
Agitation, Psychomotor0low30
Agranulocytosis0low20
AIDS0low10
AIDS Seroconversion0low10
AIDS Seropositivity0low10
Air Sickness0low20
Airsickness0low20
Akathisia0low30
Akathisia, Drug-Induced0low20
Akathisia, Tardive0low20
Akinetic-Rigid Variant of Huntington Disease0low40
Alcohol Abuse0medium122
Alcohol Addiction0medium122
Alcohol Amnestic Disorder0low10
Alcohol Amnestic Syndrome0low10
Alcohol Dependence0medium122
Alcohol Related Neurodevelopmental Disorder0low10
Alcohol Use Disorder0medium122
Alcohol Withdrawal Associated Autonomic Hyperactivity0low10
Alcohol Withdrawal Delirium0low10
Alcohol Withdrawal Hallucinosis0low10
Alcohol Withdrawal-Induced Delirium Tremens0low10
Alcohol-Induced Amnestic Psychosis0low10
Alcohol-Induced Amnestic Syndrome0low10
Alcohol-Induced Dysmnesic Psychosis0low10
Alcohol-Induced Dysmnesic Syndrome0low10
Alcohol-Induced Persisting Amnestic Disorder0low10
Alcohol-Related Birth Defects0low10
Alcoholic Cirrhosis0low10
Alcoholic Intoxication0low20
Alcoholic Intoxication, Chronic0medium122
Alcoholism0medium122
Allergic Reaction0low10
Allergy0low10
Allergy, Drug0low50
Allodynia0low20
Allodynia, Mechanical0low20
Allodynia, Tactile0low20
Allodynia, Thermal0low20
Alloxan Diabetes0low40
Alveolitis, Fibrosing0low10
Alzheimer Dementia0low10
Alzheimer Disease0low10
Alzheimer Disease, Early Onset0low10
Alzheimer Disease, Late Onset0low10
Alzheimer Sclerosis0low10
Alzheimer Syndrome0low10
Alzheimer Type Senile Dementia0low10
Alzheimer-Type Dementia (ATD)0low10
Alzheimer's Disease0low10
Alzheimer's Disease, Focal Onset0low10
Alzheimer's Diseases0low10
Ambiguous Genitalia0low20
Amebiasis0low10
Amebic Meningoencephalitis0low10
Ameboma0low10
Amelia0low10
Amenorrhea0low20
Amentia0medium101
AML M30low10
Amnesia0low20
Amnesia-Memory Loss0low20
Amnesia, Dissociative0low20
Amnesia, Global0low20
Amnesia, Hysterical0low20
Amnesia, Tactile0low20
Amnesia, Temporary0low20
Amnestic Psychosis, Alcohol-Induced0low10
Amnestic State0low20
Amoebiasis0low10
Amygdalo-Hippocampal Epilepsy0low10
Anankastic Personality0low90
Anaplastic Astrocytoma0low40
Anasarca0low50
Androgenization0low10
Anemia, Aplastic0low10
Anemia, Fanconi0low10
Anemia, Hypoplastic0low10
Anemia, Sickle Cell0medium41
Anesthesia0low30
Anesthesia Related Hyperthermia0low40
Angina Pectoris0low20
Angioedema0low10
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
Angioneurotic Edema0low10
Angor Pectoris0low20
Animal Mammary Carcinoma0low10
ANLL0low20
Anniversary Reaction0low60
Anochlesia0low180
Anomalous Ventricular Excitation Syndrome0low10
Anorexia Nervosa0low10
Anoxemia0low40
Anoxia0low40
Anoxia-Ischemia, Brain0low10
Anoxia-Ischemia, Cerebral0low10
Anoxic-Ischemic Encephalopathy0low10
Anterior Choroidal Artery Infarction0low10
Anterior Circulation Transient Ischemic Attack0low50
Anterior Fascicular Block0low10
Anti-HIV Positivity0low10
Antibiotic-Associated Colitis0low10
Antidiuretic Hormone, Inappropriate Secretion0low20
Antisocial Behavior0medium21
Antisocial Personality0medium21
Antisocial Personality Disorder0medium21
Anxiety0medium365
Anxiety Disorders0medium264
Anxiety Neuroses0medium264
Anxiety States, Neurotic0medium264
Aplastic Anaemia0low10
Aplastic Anemia0low10
Apoplexy0low10
Appetite Disorders0low20
Aprosodia0medium21
Aprosodic Speech0medium21
Aqueductal Stenosis0low10
Argyria0low10
Arrhythmia0low70
Arrhythmias, Cardiac0low70
Arrythmia0low70
Arterial Inflammation0low10
Arteriosclerosis0low90
Arteritis0low10
Arthritis, Acute Rheumatic0low10
Arthritis, Degenerative0low10
Arthritis, Rheumatic, Acute0low10
Arthritis, Rheumatoid0low10
Arthroses0low10
Arthrosis0low10
As If Personality0medium82
Ascites0low10
Aspiration Pneumonia0low10
Asterixis0low10
Asthma0medium41
Asthma, Bronchial0medium41
Astrocytoma0low40
Astrocytoma, Grade I0low40
Astrocytoma, Grade II0low40
Astrocytoma, Grade III0low40
Astrocytoma, Grade IV0medium151
Astrocytoma, Protoplasmic0low40
Astrocytoma, Subependymal Giant Cell0low40
Astroglioma0low40
Asystole0low20
Ataxia0low10
Ataxia Telangiectasia0low10
Ataxia Telangiectasia Syndrome0low10
Ataxia-Telangiectasia0low10
Ataxia, Appendicular0low10
Ataxia, Limb0low10
Ataxia, Motor0low10
Ataxia, Sensory0low10
Ataxia, Truncal0low10
Ataxy0low10
Atherosclerotic Parkinsonism0medium202
Athetoid Movements0low20
Athetosis0low20
Atonic Absence Seizure0low90
Atonic Absence Seizures0low90
Atonic Seizure0low90
Atonic Seizures0low90
Atopic Hypersensitivity0low10
Atrial Septal Defect0low10
Atrial Septal Defect Ostium Primum0low10
Atrial Septal Defects0low10
Atrioventricular Dissociation0low10
Auditory Vertigo0low10
Aura0medium102
Aural Vertigo0low10
Auriculo-Ventricular Dissociation0low10
Auriculoventricular Accessory Pathway Syndrome0low10
Autism0medium11
Autism, Early Infantile0medium11
Autism, Infantile0medium11
Autistic Disorder0medium11
Autoimmune Disease0low10
Autoimmune Diseases0low10
Autokinetic Effect0low20
Autokinetic Illusions0low20
Autonomic Hyperactivity, Alcohol Withdrawal Associated0low10
Autosomal Chromosome Disorders0low10
Autosomal Dominant Juvenile Parkinson Disease0low60
Autosomal Dominant Juvenile Parkinsonism0low60
Autosomal Dominant Parkinsonism0low60
Autosomal Recessive Juvenile Parkinson Disease0low60
Autosomal Recessive Juvenile Parkinsonism0low60
Autosomal Recessive Parkinsonism0low60
Autosome Abnormalities0low50
Autotomy Human0low40
Avoidant Personality Disorder0medium82
Awakening Epilepsy0medium102
B16 Melanoma0low20
Back Ache0medium11
Back Pain0medium11
Back Pain with Radiation0medium11
Back Pain without Radiation0medium11
Backache0medium11
Bacterial Disease0low20
Bacterial Infection0low20
Bacterial Infections0low20
Balamuthia Infection0low10
Balamuthia mandrillaris CNS Infection0low10
Balamuthia mandrillaris Meningoencephalitis0low10
Ballismus0low10
Bartholin-Patau Syndrome0low10
Basal Ganglia Diseases0medium286
Basal Ganglia Disorders0medium286
Basophilic Leukemia, Acute0low20
Behavior Disorders0medium998
Benign Focal Epilepsy, Childhood0low10
Benign Infantile Myoclonic Epilepsy0low10
Benign Neoplasms0low190
Benign Neoplasms, Brain0medium141
Benign Occipital Epilepsy0low10
Benign Occipital Epilepsy, Childhood0low10
Benign Psychomotor Epilepsy, Childhood0low30
Beriberi, Cerebral0low10
beta-Cell Tumor0low60
Bilateral Headache0low30
Bile Duct Cancer0low20
Bile Duct Neoplasms0low20
Bile Duct Obstruction0low20
Biliary Stasis0low20
Bilirubinemia0low10
Bipolar Disorder0medium352
Bipolar Mood Disorder0medium352
Birth Defects0low10
Birth Weight0low10
Black Death0low10
Black Plague0low10
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Bleb0low10
Bleeding0low10
Blepharoptosis0low20
Blepharospasm0low10
Blepharospasm-Oromandibular Dyskinesia0low20
Blepharospasm-Oromandibular Dystonia0low20
Blepharospasm-Oromandibular Dystonia Syndrome0low20
Blepharospasm-Oromandibular Dystonia Syndrome, Idiopathic0low20
Blister0low10
Blood Diseases0low10
Blood Poisoning0low20
Blood Pressure, High0low90
Blood Pressure, Low0medium51
Blood Protein Disorders0low10
Bloodstream Infection0low20
Bodily Distress Disorder0low20
Body Dysmorphic Disorders0low10
Body Image Disfunction0low10
Body Image Disorders0low10
Body Weight0medium163
Bone Cancer0low20
Bone Diseases, Metabolic0low20
Bone Loss, Age-Related0low20
Bone Loss, Osteoclastic0low50
Bone Marrow Neoplasms0low10
Bone Neoplasms0low20
Bone Resorption0low50
Borderline Personality Disorder0medium42
Bordetella pertussis Infection, Respiratory0low10
Botulism0low10
Botulism, Infantile0low10
Botulism, Toxico-Infectious0low10
Bourneville Disease0low10
Bourneville Phakomatosis0low10
Bourneville Syndrome0low10
Bourneville-Pringle Disease0low10
Bourneville-Pringle's Disease0low10
Bourneville's Disease0low10
Bourneville's Syndrome0low10
Bovine Diseases0low10
Bradyarrhythmia0low10
Bradyarrhythmias0low10
Bradycardia0low10
Brain Anoxia-Ischemia0low10
Brain Cancer0medium141
Brain Damage, Chronic0medium91
Brain Diseases0low90
Brain Disorders0low90
Brain Edema0low40
Brain Hemorrhage, Cerebral0low20
Brain Hypoxia-Ischemia0low10
Brain Injuries0low20
Brain Injuries, Acute0low20
Brain Injuries, Focal0low20
Brain Injuries, Traumatic0low10
Brain Ischemia0low10
Brain Ischemia-Anoxia0low10
Brain Ischemia-Hypoxia0low10
Brain Lacerations0low20
Brain Metastases0medium141
Brain Neoplasm, Primary0medium141
Brain Neoplasms0medium141
Brain Neoplasms, Benign0medium141
Brain Neoplasms, Malignant0medium141
Brain Neoplasms, Malignant, Primary0medium141
Brain Neoplasms, Primary Malignant0medium141
Brain Stem Ischemia, Transient0low50
Brain Stem Transient Ischemic Attack0low50
Brain Swelling0low40
Brain TIA0low50
Brain Tumor, Primary0medium141
Brain Tumor, Recurrent0medium141
Brain Tumors0medium141
Brain Vascular Disorders0low20
Brainstem Ischemia, Transient0low50
Brainstem Transient Ischemic Attack0low50
Break-Bone Fever0low10
Breakbone Fever0low10
Breast Cancer0medium122
Breast Carcinoma0medium122
Breast Neoplasms0medium122
Breast Tumors0medium122
Briquet Syndrome0low10
Bronchial Asthma0medium41
Bronchial Diseases0low10
Bronchial Hyperreactivity0low10
Bronchial Spasm0low10
Bronchitis0low10
Bronchospasm0low10
Brueghel Syndrome0low20
Bruxism0low10
Bruxomania0low10
Bubonic Plague0low10
Bulla0low10
Bullae0low10
Bullous Lesion0low10
Bundle Branch Block0low10
Bundle-Branch Block0low10
Burkitt Cell Leukemia0low20
Burkitt Leukemia0low20
Burkitt Lymphoma0low20
Burkitt Tumor0low20
Burkitt's Leukemia0low20
Burkitt's Lymphoma0low20
Burkitt's Tumor0low20
Burns0low20
Burns, Chemical0low10
C gattii Infection0low20
C neoformans Infection0low20
C. gattii Infection0low20
C. neoformans Infection0low20
Callous-Unemotional Traits0low50
Cancer0low190
Cancer of Bile Duct0low20
Cancer of Bladder0low10
Cancer of Bone0low20
Cancer of Brain0medium141
Cancer of Breast0medium122
Cancer of Colon0low50
Cancer of Head0low10
Cancer of Head and Neck0low10
Cancer of Kidney0low20
Cancer of Liver0low70
Cancer of Lung0low150
Cancer of Nasopharynx0low10
Cancer of Neck0low10
Cancer of Ovary0low20
Cancer of Pancreas0low140
Cancer of Pituitary0low160
Cancer of Prostate0low20
Cancer of Skin0low60
Cancer of Stomach0low20
Cancer of the Adrenal Gland0low60
Cancer of the Bile Duct0low20
Cancer of the Bladder0low10
Cancer of the Bone0low20
Cancer of the Brain0medium141
Cancer of the Breast0medium122
Cancer of the Colon0low50
Cancer of the Head0low10
Cancer of the Head and Neck0low10
Cancer of the Kidney0low20
Cancer of the Liver0low70
Cancer of the Lung0low150
Cancer of the Nasopharynx0low10
Cancer of the Neck0low10
Cancer of the Ovary0low20
Cancer of the Pancreas0low140
Cancer of the Pituitary0low160
Cancer of the Prostate0low20
Cancer of the Skin0low60
Cancer of the Stomach0low20
Cancer of the Thymus0low10
Cancer of the Thyroid0low20
Cancer of Thymus0low10
Cancer of Thyroid0low20
Cancer, Hepatocellular0low70
Cancer, Radiation-Induced0low10
Candida Infection0low20
Candidiasis0low20
Candidiasis, Oral0low10
Canine Diseases0low10
Car Sickness0low20
Carbon Monoxide Poisoning0low10
Carbon Tetrachloride Poisoning0low30
Carcinogenesis0low10
Carcinoma0low50
Carcinoma 256, Walker0low10
Carcinoma, Anaplastic0low50
Carcinoma, Cribriform0low80
Carcinoma, Ductal0low10
Carcinoma, Ductal, Pancreatic0low10
Carcinoma, Ehrlich Tumor0low90
Carcinoma, Epidermoid0low60
Carcinoma, Granular Cell0low80
Carcinoma, Hepatocellular0low100
Carcinoma, Hypernephroid0low10
Carcinoma, Non-Small Cell Lung0low30
Carcinoma, Non-Small-Cell Lung0low30
Carcinoma, Oat Cell0low20
Carcinoma, Pancreatic Ductal0low10
Carcinoma, Planocellular0low60
Carcinoma, Renal Cell0low10
Carcinoma, Small Cell0low20
Carcinoma, Spindle-Cell0low50
Carcinoma, Squamous0low60
Carcinoma, Squamous Cell0low60
Carcinoma, Squamous Cell of Head and Neck0low10
Carcinoma, Thymic0low10
Carcinoma, Tubular0low80
Carcinoma, Undifferentiated0low50
Carcinomatosis0low50
Carcinosarcoma 256, Walker0low10
Cardiac Arrest0low20
Cardiac Arrhythmia0low70
Cardiac Arrhythmias0low70
Cardiac Death0low10
Cardiac Diseases0low10
Cardiac Disorders0low10
Cardiac Dysrhythmia0low70
Cardiac Failure0low40
Cardiac Hypertrophy0low20
Cardiac Neurosis0low10
Cardiac Septal Defect0low10
Cardiac Septal Defects0low10
Cardiac Toxicity0low10
Cardiomegaly0low20
Cardiometabolic Syndrome0low10
Cardiomyopathies0low30
Cardiomyopathies, Primary0low30
Cardiomyopathies, Secondary0low30
Cardiopulmonary Arrest0low20
Cardiotoxicity0low10
Cardiovascular Diseases0low30
Cardiovascular Stroke0low60
Carditis0low20
Carotid Circulation Transient Ischemic Attack0low50
Carsickness0low20
Catalepsy0low180
Cataleptic Attacks0low10
Cataplexy0low10
Cataract0low20
Cataract, Membranous0low20
Catarrh0low10
Catatonia0low100
Catatonia, Malignant0low100
Catatonia, Organic0low100
Catatonic Rigidity0low10
Catatonic Schizophrenia0low40
Cattle Diseases0low10
Cavernitis, Fibrous0medium21
CCl4 Poisoning0low30
Celiac Disease0low10
Celiac Sprue0low10
Cell Transformation, Neoplastic0low40
Cell Transformation, Viral0low50
Cellulitis0low10
Central European Encephalitis0low10
Central Hypothyroidism0low40
Central Nervous System Disease0low10
Central Nervous System Diseases0low10
Central Nervous System Disorder0low10
Central Nervous System Disorders0low10
Central Nervous System Disorders, Intracranial0low90
Central Nervous System Intracranial Disorders0low90
Central Nervous System Neoplasm0low10
Central Nervous System Neoplasms0low10
Central Nervous System Neoplasms, Primary0low10
Central Nervous System Protozoal Infections0low10
Central Nervous System Tumor0low10
Central Nervous System Tumors0low10
Centrala nervsystemets sjukdomar@sv0low10
Cephalalgia0low30
Cephalgia0low30
Cephalgia Syndromes0low10
Cephalodynia0low30
Cerea Flexibilitas0low180
Cerebral Anoxia-Ischemia0low10
Cerebral Astrocytoma0low40
Cerebral Edema0low40
Cerebral Edema, Cytotoxic0low40
Cerebral Edema, Vasogenic0low40
Cerebral Hemorrhage0low20
Cerebral Hypoxia-Ischemia0low10
Cerebral Infarct0low10
Cerebral Infarction0low10
Cerebral Infarction, Left Hemisphere0low10
Cerebral Infarction, Right Hemisphere0low10
Cerebral Ischemia0low10
Cerebral Ischemia-Anoxia0low10
Cerebral Ischemia-Hypoxia0low10
Cerebral Ischemia, Transient0low50
Cerebral Parenchymal Hemorrhage0low20
Cerebral Protozoal Infections0low10
Cerebral Pseudosclerosis0low10
Cerebral Sclerosis0low10
Cerebral Stroke0low10
Cerebral Ventriculomegaly0low10
Cerebral, Left Hemisphere, Infarction0low10
Cerebral, Right Hemisphere, Infarction0low10
Cerebromeningitis0low10
Cerebrovascular Accident0low10
Cerebrovascular Accident, Acute0low10
Cerebrovascular Apoplexy0low10
Cerebrovascular Diseases0low20
Cerebrovascular Disorders0low20
Cerebrovascular Insufficiency0low20
Cerebrovascular Moyamoya Disease0low10
Cerebrovascular Occlusion0low20
Cerebrovascular Stroke0low10
Cervical Migraine Syndrome0low20
Chemical and Drug Induced Liver Injury0low160
Chemical Burns0low10
Chemical Dependence0medium151
Chemically-Induced Liver Toxicity0low160
Child Behavior Disorders0medium81
Child Development Deviations0low10
Child Development Disorders0low10
Child Development Disorders, Pervasive0low10
Child Development Disorders, Specific0low10
Childhood Behavior Disorders0medium81
Childhood Benign Focal Epilepsy0low10
Childhood Benign Occipital Epilepsy0low10
Childhood Benign Psychomotor Epilepsy0low30
Childhood Cerebral Astrocytoma0low40
Childhood Schizophrenia0medium103
Childhood Tic Disorders0low10
Childhood Torsion Disease0medium21
Childhood-Onset Schizophrenia0medium103
Chloasma0low10
Cholangiocarcinoma0low20
Cholangiocellular Carcinoma0low20
Cholecystitis0low10
Cholelithiasis0low20
Cholera Infantum0low20
Cholestasis0low20
Chorea0low80
Chorea Disorders0low80
Chorea Syndromes0low80
Chorea, Benign Hereditary0low80
Chorea, Chronic Progressive0low80
Chorea, Chronic Progressive Hereditary (Huntington)0low40
Chorea, Rheumatic0low80
Chorea, Senile0low80
Chorea, Sydenham0low80
Choreatic Disorders0low80
Choreatic Syndromes0low80
Choreic Movement0low80
Choreiform Movement0low80
Choroby OUN@pl0low10
Chromophil Renal Cell Carcinoma0low10
Chromophobe Renal Cell Carcinoma0low10
Chromosomal Aberrations0low50
Chromosomal Disorders0low10
Chromosome 13 Duplication0low10
Chromosome 13 Trisomy Syndrome0low10
Chromosome 6-Linked Autosomal Recessive Parkinsonism0low60
Chromosome Aberrations0low50
Chromosome Abnormalities0low50
Chromosome Abnormality Disorders0low10
Chromosome Deletion0low10
Chromosome Disorders0low10
Chronic Actinic Dermatitis0low20
Chronic Daily Headache0low10
Chronic Disease0medium6637
Chronic Encephalopathy0medium91
Chronic Headache0low10
Chronic Idiopathic Intestinal Pseudo-Obstruction0low10
Chronic Illness0medium6637
Chronic Insomnia0low40
Chronic Lung Injury0low10
Chronic Motor and Vocal Tic Disorder0medium72
Chronic Motor or Vocal Tic Disorder0low10
Chronic Post-Traumatic Stress Disorder0low10
Chronic Progressive Hereditary Chorea (Huntington)0low40
Chronically Ill0medium6637
Cirrhosis0low10
Cirrhosis, Liver0low10
Classical Dengue0low10
Classical Dengue Fever0low10
Claustrophobia0low30
Clear Cell Renal Carcinoma0low10
Clear Cell Renal Cell Carcinoma0low10
Cleft Palate0low10
Cleft Palate, Isolated0low10
Clerambault Syndrome0medium102
Clonic Seizure0low90
Clonic Seizures0low90
Clostridioides difficile Infection0low10
Clostridioides Infections0low10
Clostridioides perfringens Food Poisoning0low10
Clostridioides perfringens Infections0low10
Clostridioides sordellii Infection0low10
Clostridium botulinum Infection0low10
Clostridium difficile Infection0low10
Clostridium difficile Infections0low10
Clostridium Enterocolitis0low10
Clostridium Infections0low10
Clostridium perfringens Food Poisoning0low10
Clostridium perfringens Infections0low10
Clostridium sordellii Infection0low10
Clostridium sordellii Infections0low10
Clostridium tetani Infection0low20
Cluttering0medium21
CNS Disease0low10
CNS Diseases0low10
CNS Disorders, Intracranial0low90
CNS Neoplasm0low10
CNS Neoplasms0low10
CNS Protozoal Infections0low10
Coagulation, Disseminated Intravascular0low10
Coarse Tremor0medium61
Cognition Disorders0low40
Cogwheel Rigidity0low10
Cold, Common0low10
Colitis Gravis0low10
Colitis, Pseudomembranous0low10
Colitis, Ulcerative0low10
Collecting Duct Carcinoma0low10
Collecting Duct Carcinoma (Kidney)0low10
Collecting Duct Carcinoma of the Kidney0low10
Colon Cancer0low50
Colon Neoplasms0low50
Colonic Cancer0low50
Colonic Diseases0low10
Colonic Neoplasms0low50
Colorectal Cancer0low10
Colorectal Carcinoma0low10
Colorectal Neoplasms0low10
Colorectal Tumors0low10
Coma0low60
Coma, Hyperglycemic Hyperosmolar Nonketotic0low10
Comatose0low60
Combined Multiple Motor and Vocal Tic Disorder0medium72
Combined Vocal and Multiple Motor Tic Disorder0medium72
Common Cold0low10
Communicating Hydrocephalus0low10
Complete Trisomy 13 Syndrome0low10
Complex Partial Seizure0low90
Complex Partial Seizures0low90
Complication, Postoperative0low20
Complications, Pregnancy0low60
Conduct Disorder0low50
Congenital Abnormalities0low10
Congenital Adrenal Hyperplasia0low10
Congenital Defects0low10
Congenital Heart Defect0low20
Congenital Heart Defects0low20
Congenital Heart Disease0low20
Congenital Hydrocephalus0low10
Congenital Micrognathia0low10
Congenital Micrognathism0low10
Congenital Short Bowel Syndrome0low10
Congenital Zika Syndrome0low20
Congenital Zika Virus Infection0low20
Congestive Heart Failure0low40
Congestive Ophthalmopathy0low10
Consciousness, Loss of0low10
Consumption Coagulopathy0low10
Contact Dermatitis0low20
Continuous Tremor0medium61
Convulsion0low90
Convulsion, Non-Epileptic0low90
Convulsions0low90
Convulsive Seizure0low90
Convulsive Seizures0low90
Coordination Impairment0low10
Copper Storage Disease0low10
Cornea Injuries0low10
Corneal Abrasions0low10
Corneal Damage0low10
Corneal Injuries0low10
Corneal Opacity0low20
Corneal Scar0low10
Corneal Trauma0low10
Coronary Disease0low90
Coronary Heart Disease0low90
Coronavirus Disease 20190low10
Coronavirus Disease-190low10
Cortical Lewy Body Disease0low10
Coryza, Acute0low10
COVID-190low10
COVID-19 Pandemic0low10
COVID-19 Pandemics0low10
COVID-19 Virus Disease0low10
COVID-19 Virus Infection0low10
COVID190low10
Cramp0low10
Cranial Pain0low30
Craniocerebral Injuries0low10
Craniocerebral Trauma0low10
Crescendo Transient Ischemic Attacks0low50
Crushing Skull Injury0low10
Cryptococcosis0low20
Cryptococcus gattii Infection0low20
Cryptococcus Infection0low20
Cryptococcus Infections0low20
Cryptococcus neoformans Infection0low20
Cryptogenic Infantile Spasms0low10
Cryptogenic Myoclonic Epilepsy0low10
Cryptogenic West Syndrome0low10
Curling Ulcer0low20
Curling's Ulcer0low20
CVA (Cerebrovascular Accident)0low10
Cystic Echinococcosis0low10
Cystic Fibrosis0low30
Cystic Fibrosis of Pancreas0low30
Cysts, Hydatid0low10
Cytogenetic Aberrations0low50
Cytogenetic Abnormalities0low50
Cytotoxic Brain Edema0low40
Cytotoxic Cerebral Edema0low40
Darkness Tremor0medium61
Day Blindness0low20
Death0low10
Death, Sudden0low20
Defects, Congenital0low10
Defects, Congenital Heart0low20
Deficiency, Mental0medium162
Deficiency, Oxygen0low40
Deficiency, Vitamin D0low30
Deformities0low10
Deglutition Disorders0medium21
Delayed Effects, Prenatal Exposure0low10
Delayed Hypersensitivity0low20
Delayed Onset Post-Traumatic Stress Disorder0low10
Delirium0low40
Delirium of Mixed Origin0low40
Delirium Tremens0low10
Delirium Tremens, Alcohol Withdrawal Induced0low10
Delirium, Dementia, Amnestic, Cognitive Disorders0medium102
Delusional Disorder0medium287
Dementia0medium101
Dementia Praecox0medium35997
Dementia, Alzheimer Type0low10
Dementia, Lewy Body0low10
Dementia, Presenile0low10
Dementia, Primary Senile Degenerative0low10
Dementia, Senile0low10
Dengue0low10
Dengue Fever0low10
Depression0medium707
Depression, Bipolar0medium352
Depression, Endogenous0medium371
Depression, Involutional0medium121
Depression, Neurotic0medium371
Depression, Reactive0low60
Depression, Reactive, Psychotic0low10
Depression, Unipolar0medium371
Depressive Disorder0medium371
Depressive Disorder, Major0medium121
Depressive Syndrome0medium371
Dermatitis Medicamentosa0low30
Dermatitis Venenata0low20
Dermatitis, Actinic0low20
Dermatitis, Adverse Drug Reaction0low30
Dermatitis, Contact0low20
Dermatitis, Contact, Phototoxic0low30
Dermatitis, Occupational0low10
Dermatitis, Phototoxic0low30
Dermatoses0low50
Dermatosis0low50
Dermatosis, Industrial0low10
Determination of Death0low10
Development Disorders, Child0low10
Developmental Academic Disability0low20
Developmental Academic Disorder0low20
Developmental Delay Disorders0low10
Developmental Disabilities0low10
Developmental Disabilities of Scholastic Skills0low20
Developmental Disorders of Scholastic Skills0low20
Developmental Psychomotor Disorders0low10
Dextro-Looped Transposition of the Great Arteries0low10
Di Guglielmo Disease0low30
Di Guglielmo's Disease0low30
Diabetes Mellitus0medium11
Diabetes Mellitus, Adult-Onset0low10
Diabetes Mellitus, Experimental0low40
Diabetes Mellitus, Ketosis-Resistant0low10
Diabetes Mellitus, Maturity-Onset0low10
Diabetes Mellitus, Non Insulin Dependent0low10
Diabetes Mellitus, Non-Insulin-Dependent0low10
Diabetes Mellitus, Noninsulin Dependent0low10
Diabetes Mellitus, Noninsulin-Dependent0low10
Diabetes Mellitus, Slow-Onset0low10
Diabetes Mellitus, Stable0low10
Diabetes Mellitus, Type 20low10
Diabetes Mellitus, Type II0low10
Diagnosis, Psychiatric0medium998
Diarrhea0low50
Diffuse Large B-Cell Lymphoma0low10
Diffuse Large-Cell Lymphoma0low10
Diffuse Lewy Body Disease0low10
Diffuse Mixed Small and Large Cell Lymphoma0low10
Diffuse Mixed-Cell Lymphoma0low10
Diffuse Small Cleaved-Cell Lymphoma0low10
Diffuse Undifferentiated Lymphoma0low10
Diffuse, Large B-Cell, Lymphoma0low10
Digestive Epilepsy0low10
DIMS (Disorders of Initiating and Maintaining Sleep)0low40
Disabilities, Developmental0low10
Disability, Intellectual0medium162
Disc, Herniated0low20
Disease0low30
Disease Exacerbation0low10
Disease Models, Animal0low230
Disease Progression0low10
Disease, Pulmonary0low10
Diseases, Metabolic0low20
Diseases, Occupational0low30
Diseases, Pulmonary0low10
Disk Prolapse0low20
Disk, Herniated0low20
Disorder, Borderline Personality0medium42
Disorders of Initiating and Maintaining Sleep0low40
Disorders of Sex Development0low20
Disorders of Sexual Development0low20
Disruptive, Impulse Control, and Conduct Disorders0medium11
Disseminated Coagulation, Intravascular0low10
Disseminated Intravascular Coagulation0low10
Dissociation0low20
Dissociative Disorders0low20
Dissociative Identity Disorder0low10
Dissociative Reaction0low20
Distorted Hearing0low10
Doenu00E7as do Sistema Nervoso Central@pt0low10
Dog Diseases0low10
Doose Syndrome0low10
Dravet Syndrome0low10
Drop Attack0low10
Dropsy0low50
Drug Abuse0medium151
Drug Addiction0medium151
Drug Allergy0low50
Drug Dependence0medium151
Drug Eruptions0low30
Drug Habituation0medium151
Drug Hypersensitivity0low50
Drug Overdose0low50
Drug Side Effects0low60
Drug Toxicity0low60
Drug Use Disorders0medium151
Drug Withdrawal Symptoms0medium242
Drug-Induced Abnormalities0low70
Drug-Induced Acute Liver Injury0low160
Drug-Induced Akathisia0low20
Drug-Induced Liver Disease0low160
Drug-Induced Liver Injury0low160
Drug-Related Side Effects and Adverse Reactions0low60
Drunkenness0low20
Dual Personality0low10
Duct-Cell Carcinoma of the Pancreas0low10
Duct-Cell Carcinoma, Pancreas0low10
Ductal Carcinoma0low10
Ductal Carcinoma of the Pancreas0low10
Duodenal Ulcer0low20
Dysacusis0low10
Dysarthosis0low10
Dysarthria0low10
Dysarthria, Flaccid0low10
Dysarthria, Guttural0low10
Dysarthria, Mixed0low10
Dysarthria, Scanning0low10
Dysarthria, Spastic0low10
Dyscoordination0low10
Dysembryoma0low10
Dysglossia0medium21
Dyskinesia Syndromes0medium4610
Dyskinesia, Drug-Induced0low210
Dyskinesia, Medication-Induced0low210
Dyskinesias0low10
Dyskinesias, Paroxysmal0low80
Dyslalia0medium21
Dysmetabolic Syndrome X0low10
Dyspepsia0low10
Dysphagia0medium21
Dyssocial Behavior0medium21
Dyssynergia0low10
Dysthyroid Ophthalmopathy0low10
Dystonia0low60
Dystonia Deformans Musculorum0medium21
Dystonia Deformans Progressiva0medium21
Dystonia Musculorum Deformans0medium21
Dystonia, Diurnal0low60
Dystonia, Limb0low60
Dystonia, Paroxysmal0low60
E coli Infections0low30
E. coli Infection0low30
Early Awakening0low40
Early Childhood Epilepsy, Myoclonic0low10
Early Childhood, Myoclonic Epilepsy0low10
Early Onset Alzheimer Disease0low10
Eating and Feeding Disorders0low20
Eating Disorders0low20
Echinococcosis0low10
Echinococcus Granulosus Infection0low10
Echinococcus Infection0low10
Ectromelia0low10
Eczema, Contact0low20
Edema0low50
Edema, Pulmonary0low10
Edemas, Pulmonary0low10
Edematous Ophthalmopathy0low10
Effect, Autokinetic0low20
Effort Syndrome0low10
Ehrlich Ascites Tumor0low90
Electrolytes0low10
Electron Transport Chain Deficiencies, Mitochondrial0low10
Elevated Cholesterol0low30
Embryopathies0low10
Emergencies0low10
Emesis0low90
Empyema, Gall Bladder0low10
Empyema, Gallbladder0low10
Encephalitis, Central European0low10
Encephalitis, European Tick-Borne0low10
Encephalitis, Far Eastern Russian0low10
Encephalitis, Louping Ill0low10
Encephalitis, Polio0low10
Encephalitis, Russian Spring-Summer0low10
Encephalitis, Tick-Borne0low10
Encephalomeningitis0low10
Encephalon Diseases0low90
Encephalopathy0low90
Encephalopathy, Anoxic-Ischemic0low10
Encephalopathy, Chronic0medium91
Encephalopathy, Gayet-Wernicke0low10
Encephalopathy, Hepatic0low10
Encephalopathy, Hepatocerebral0low10
Encephalopathy, Hypoxic-Ischemic0low10
Encephalopathy, Ischemic0low10
Encephalopathy, Myoclonic0low10
Encephalopathy, Portal-Systemic0low10
Encephalopathy, Portosystemic0low10
Encephalopathy, Toxic0low10
Encephalopathy, Traumatic0low10
Encephalopathy, Wernicke0low10
Encephalopathy, Wernicke's0low10
End Of Life0low10
End-Of-Life0low10
Enfermedades del Sistema Nervioso Central@es0low10
Enlarged Heart0low20
Entamoeba histolytica Infection0low10
Entamoeba Infections0low10
Entamoebiasis0low10
Enteric Neuropathy0low10
Enteritis, Pseudomembranous0low10
Enterocolitis, Pseudomembranous0low10
Entomophthoramycosis0low10
Eosinophilia0low10
Eosinophilia, Tropical0low10
Epidemic Acute Poliomyelitis0low10
Epidermolysis Bullosa0low10
Epilepsies, Myoclonic0low10
Epilepsies, Partial0low10
Epilepsy0medium102
Epilepsy, Benign Occipital0low10
Epilepsy, Benign Psychomotor, Childhood0low30
Epilepsy, Cryptogenic0medium102
Epilepsy, Early Childhood, Myoclonic0low10
Epilepsy, Focal0low10
Epilepsy, Lateral Temporal0low30
Epilepsy, Localization-Related0low10
Epilepsy, Myoclonic, Early Childhood0low10
Epilepsy, Myoclonic, Infantile0low10
Epilepsy, Myoclonic, Infantile, Benign0low10
Epilepsy, Myoclonic, Infantile, Severe0low10
Epilepsy, Myoclonus0low10
Epilepsy, Partial0low10
Epilepsy, Simple Partial0low10
Epilepsy, Temporal Lobe0low30
Epilepsy, Uncinate0low30
Epileptic Seizure0low90
Epileptic Seizures0low90
Epiloia0low10
Epithelial Neoplasms, Malignant0low50
Epithelial Tumors, Malignant0low50
Epithelioma0low50
ER-Negative PR-Negative HER2-Negative Breast Cancer0low20
ER-Negative PR-Negative HER2-Negative Breast Neoplasms0low20
Erythema0low20
Erythremic Myelosis0low30
Erythroblastic Leukemia, Acute0low30
Erythroleukemia0low30
Escherichia coli Infections0low30
Esophageal Dysphagia0medium21
Etat Marbre0medium4610
Ethanol Abuse0medium122
European Tick-Borne Encephalitis0low10
Excitement, Psychomotor0low30
Experimental Diabetes Mellitus0low40
Experimental Hepatoma0low40
Experimental Hepatomas0low40
Experimental Leukemia0low120
Experimental Leukemias0low120
Experimental Liver Neoplasms0low40
Experimental Mammary Neoplasms0low10
Experimental Melanoma0low20
Experimental Melanomas0low20
Experimental Neoplasms0low190
Experimental Parkinson Disease0low60
Experimental Parkinsonism0low60
Experimental Parkinsonism, MPTP-Induced0low60
Extensor Rigidity0low10
Extrahepatic Cholangiocarcinoma0low20
Extrapyramidal Disorders0medium286
Extrapyramidal Rigidity0low10
Extravascular Hemolysis0low150
Eye Diseases0low30
Eye Disorders0low30
Eyelid Diseases0low10
FAE (Fetal Alcohol Effects)0low10
Fainting0low10
False Bundle-Branch Block Syndrome0low10
Familial Alzheimer Disease (FAD)0low10
Familial Dementia0medium101
Familial Juvenile Parkinsonism0low60
Familial Parkinson Disease, Autosomal Recessive0low60
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Far Eastern Russian Encephalitis0low10
Fascicular Block0low10
FASD0low10
Fasting Hypoglycemia0low10
Fatigue0low10
Fatty Liver0low10
Feeding and Eating Disorders0low20
Feeding Disorders0low20
Fetal Alcohol Spectrum Disorder0low10
Fetal Alcohol Spectrum Disorders0low10
Fetal Alcohol Syndrome0low10
Fetal Anomalies0low10
Fetal Cerebral Ventriculomegaly0low10
Fetal Diseases0low10
Fetal Malformations0low10
Fever0low50
Fever, Zika0low20
Fibrillary Astrocytoma0low40
Fibrocystic Disease of Pancreas0low30
Fibrosarcoma0low10
Fibroses, Pulmonary0low10
Fibrosis0low10
Fibrosis, Liver0low10
Fibrosis, Pulmonary0low10
Fine Tremor0medium61
Finger Injuries0low10
Fistula0low10
Flexibility, Waxy0low180
Focal Brain Injuries0low20
Focal Neurologic Deficits0low30
Focal Onset Alzheimer's Disease0low10
Focal Seizure Disorder0low10
Foodborne Botulism0low10
Forehead Trauma0low10
Fra(X) Syndrome0low10
Fragile X Mental Retardation Syndrome0low10
Fragile X Syndrome0low10
Fragile X-F Mental Retardation Syndrome0low10
FRAXA Syndrome0low10
FRAXE Syndrome0low10
Freckles0low10
Frigidity0low10
Frontal Region Trauma0low10
Frostbite0low10
Fugue0low20
Fulminant Hepatic Failure with Cerebral Edema0low10
Functional Gastrointestinal Disorders0low20
Fused Legs and Feet0low10
Gait Disorders, Animal0low10
Galactorrhea0low20
Gallbladder Inflammation0low10
Gallstone Disease0low20
Gastric Acid Aspiration Syndrome0low10
Gastric Cancer0low20
Gastric Cancer, Familial Diffuse0low20
Gastric Diseases0low10
Gastric Neoplasms0low20
Gastric Stasis0low10
Gastric Ulcer0low20
Gastritis0low30
Gastroduodenal Ulcer0low20
Gastroenteritis0low10
Gastrointestinal Diseases0low20
Gastrointestinal Disorders0low20
Gastrointestinal Disorders, Functional0low20
Gastroparesis0low10
Gayet-Wernicke Encephalopathy0low10
Gegenhalten0low10
Gelastic Epilepsy0low10
Gelineau Syndrome0low10
Gelineau's Syndrome0low10
Gemistocytic Astrocytoma0low40
Generalized Absence Seizure0low90
Generalized Absence Seizures0low90
Generalized Headache0low30
Generalized Tonic-Clonic Seizures0low90
Genetic Predisposition0low10
Genetic Predisposition to Disease0low10
Genetic Susceptibility0low10
Genital Ambiguity0low20
Genitourinary Abnormalities0low10
Germinoblastoma0low30
Giant Cell Glioblastoma0medium151
Giant Osteoid Osteoma0low10
Giardia duodenalis Infection0low20
Giardia Infection0low20
Giardia intestinalis Infection0low20
Giardia lamblia Infection0low20
Giardiasis0low20
Gilles de la Tourette Disorder0medium72
Gilles de la Tourette Syndrome0medium72
Gilles de la Tourette's Disease0medium72
Gilles De La Tourette's Syndrome0medium72
Glial Cell Tumors0low140
Glioblastoma0medium151
Glioblastoma Multiforme0medium151
Glioma0low140
Glioma, Astrocytic0low40
Glomerulonephritis, Lupus0low10
Glossitis0low10
Gluten Enteropathy0low10
Gluten-Sensitive Enteropathy0low10
Granulocytic Leukemia0low10
Granulocytic Leukemia, Chronic0low10
Granulocytopenia0low20
Granuloma0low10
Granulomas0low10
Graves Ophthalmopathy0low10
Graves Orbitopathy0low10
Grawitz Tumor0low10
Group A Strep Infection0low10
Group A Streptococcal Infection0low10
Group A Streptococcal Infections0low10
Group B Strep Infection0low10
Group B Streptococcal Infection0low10
Group B Streptococcal Infections0low10
Growth Retardation, Facial Abnormalities, and Central Nervous System Dysfunction0low10
Gynecomastia0low10
Habit Chorea0low10
Habit Spasm0low10
Habituation Spasm0low10
Haemolysis0low150
Halitosis0low10
Hallervorden-Spatz Disease0low10
Hallervorden-Spatz Syndrome0low10
Hallucination of Body Sensation0medium202
Hallucinations0medium202
Hallucinations, Auditory0medium202
Hallucinations, Dissociative0medium202
Hallucinations, Elementary0medium202
Hallucinations, Formed, of People0medium202
Hallucinations, Gustatory0medium202
Hallucinations, Hypnagogic0medium202
Hallucinations, Hypnapompic0medium202
Hallucinations, Internal Body Sensation0medium202
Hallucinations, Kinesthetic0medium202
Hallucinations, Mood Congruent0medium202
Hallucinations, Mood Incongruent0medium202
Hallucinations, Olfactory0medium202
Hallucinations, Organic0medium202
Hallucinations, Reflex0medium202
Hallucinations, Sensory0medium202
Hallucinations, Somatic0medium202
Hallucinations, Tactile0medium202
Hallucinations, Verbal Auditory0medium202
Hallucinations, Visual0medium202
Hallucinations, Visual, Formed0medium202
Hallucinations, Visual, Unformed0medium202
Hammond Disease0low20
Hammond's Disease0low20
Hansen Disease0low10
Hansen's Disease0low10
Harding Passey Melanoma0low20
HbS Disease0medium41
Head and Neck Cancer0low10
Head and Neck Neoplasm0low10
Head and Neck Neoplasms0low10
Head and Neck Squamous Cell Carcinoma0low10
Head And Neck Squamous Cell Carcinomas0low10
Head Cancer0low10
Head Injuries0low10
Head Injuries, Multiple0low10
Head Injury, Minor0low10
Head Injury, Open0low10
Head Injury, Superficial0low10
Head Neoplasm0low10
Head Neoplasms0low10
Head Pain0low30
Head Trauma0low10
Head, Neck Neoplasms0low10
Headache0low30
Headache Disorders0low10
Headache Syndromes0low10
Headache, Intractable0low10
Headache, Migraine0low20
Headache, Tension0low10
Hearing Disorders0low10
Heart Abnormalities0low20
Heart Arrest0low20
Heart Attack0low60
Heart Block0low10
Heart Decompensation0low40
Heart Defect, Congenital0low20
Heart Defects, Congenital0low20
Heart Disease, Ischemic0low20
Heart Diseases0low10
Heart Disorders0low10
Heart Enlargement0low20
Heart Failure0low40
Heart Failure, Congestive0low40
Heart Failure, Left-Sided0low40
Heart Failure, Right-Sided0low40
Heart Hypertrophy0low20
Heart Septal Defect0low10
Heart Septal Defects0low10
Heart Septal Defects, Atrial0low10
Heart, Malformation Of0low20
Heat Collapse0low10
Heat Exhaustion0low10
Heat Prostration0low10
Hebephrenic Schizophrenia0medium21
Hematologic Diseases0low10
Hematological Diseases0low10
Hemeralopia0low20
Hemiballism0low10
Hemiballismus0low10
Hemicrania0low30
Hemicrania Migraine0low20
Hemimelia0low10
Hemoglobin S Disease0medium41
Hemoglobinuria, Paroxysmal0low10
Hemolysis0low150
Hemorrhage0low10
Hemorrhage, Cerebral0low20
Hemorrhage, Cerebrum0low20
Hemorrhage, Subarachnoid0low20
Hemorrhagic Diathesis0low10
Hemorrhagic Disorders0low10
Henneberg Syndrome0low10
Hepatic Cancer0low70
Hepatic Cirrhosis0low10
Hepatic Cirrhosis, Alcoholic0low10
Hepatic Coma0low10
Hepatic Encephalopathy0low10
Hepatic Form of Wilson Disease0low10
Hepatic Neoplasms0low70
Hepatic Stupor0low10
Hepatitis0low20
Hepatitis A0low10
Hepatitis C0low10
Hepatitis, Drug-Induced0low160
Hepatitis, Infectious0low10
Hepatitis, Toxic0low160
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted0low10
Hepato-Neurologic Wilson Disease0low10
Hepatocellular Cancer0low70
Hepatocellular Carcinoma0low100
Hepatocerebral Degeneration0low10
Hepatocerebral Encephalopathy0low10
Hepatolenticular Degeneration0low10
Hepatolenticular Degeneration Syndrome0low10
Hepatoma0low100
Hepatoma, Experimental0low40
Hepatoma, Morris0low40
Hepatoma, Novikoff0low40
Hepatomas, Experimental0low40
Hereditary Chorea0low80
Hereditary Progressive Chorea Without Dementia0low80
Hermaphroditism0low20
Herniated Disc0low20
Herniated Disk0low20
Herpes Simplex0low10
Herpes Simplex Virus Infection0low10
High Cholesterol Levels0low30
Hirsutism0low10
Histiocytic Lymphoma0low10
Histiocytic Lymphoma, Diffuse0low10
HIV Antibody Positivity0low10
HIV Coinfection0low20
HIV Infections0low20
HIV Seroconversion0low10
HIV Seropositivity0low10
HNSCC0low10
Hospital-Acquired Condition0low30
HTLV-III Infections0low20
HTLV-III Seroconversion0low10
HTLV-III Seropositivity0low10
HTLV-III-LAV Infections0low20
Human Mammary Carcinoma0medium122
Huntington Chorea0low40
Huntington Chronic Progressive Hereditary Chorea0low40
Huntington Disease0low40
Huntington Disease, Akinetic-Rigid Variant0low40
Huntington Disease, Juvenile0low40
Huntington Disease, Juvenile-Onset0low40
Huntington Disease, Late Onset0low40
Huntington's Chorea0low40
Huntington's Disease0low40
Hydatid Cyst0low10
Hydatid Disease0low10
Hydatidosis0low10
Hydrocephalus0low10
Hydrocephalus Ex-Vacuo0low10
Hydrocephaly0low10
Hydronephrosis0low10
Hydrops0low50
Hydroxymethylbilane Synthase Deficiency0low10
Hymenolepiasis0low20
Hymenolepis Infection0low20
Hyperactivity, Motor0low40
Hyperadrenalism0low10
Hyperadrenocorticism0low10
Hyperalgesia0low20
Hyperalgesia, Mechanical0low20
Hyperalgesia, Primary0low20
Hyperalgesia, Secondary0low20
Hyperalgesia, Tactile0low20
Hyperalgesia, Thermal0low20
Hyperalgesic Sensations0low20
Hyperalgia0low20
Hyperalgia, Mechanical0low20
Hyperalgia, Primary0low20
Hyperalgia, Secondary0low20
Hyperammonemia0low10
Hyperbilirubinemia0low10
Hypercalcemia0low10
Hypercholesteremia0low30
Hypercholesterolemia0low30
Hypercorticism0low10
Hyperemesis Gravidarum0low10
Hyperglycemia0medium21
Hyperglycemia, Postprandial0medium21
Hyperglycemic Hyperosmolar Nonketotic Coma0low10
Hyperkinesia0low40
Hyperkinesia, Generalized0low40
Hyperkinesis0low40
Hyperkinetic Heart Syndrome0low10
Hyperkinetic Movements0low40
Hypernatremia0low10
Hypernephroma0low10
Hyperosmolar Hyperglycemic Nonketotic Coma0low10
Hyperosmolar Hyperglycemic State0low10
Hyperosmolar Hyperglycemic Syndrome0low10
Hyperosmolar Nonketotic Coma0low10
Hyperplasia0low20
Hyperplasia, Congenital Adrenal0low10
Hyperprolactinaemia0low20
Hyperprolactinemia0low20
Hyperpyrexia, Malignant0low40
Hypersensitivity0low10
Hypersensitivity, Atopic0low10
Hypersensitivity, Contact0low20
Hypersensitivity, Delayed0low20
Hypersensitivity, Drug0low50
Hypersensitivity, Immediate0low10
Hypersensitivity, Tuberculin-Type0low20
Hypersensitivity, Type I0low10
Hypersensitivity, Type IV0low20
Hypertension0low90
Hypertension, Pulmonary0low20
Hyperthermia of Anesthesia0low40
Hyperthermia, Malignant0low40
Hyperthyroid0low20
Hyperthyroidism0low20
Hypertrichosis0low10
Hypertrophy0low30
Hypoactive Sexual Desire Disorder0low10
Hypoadrenalism0low20
Hypochondriacal Neuroses0low30
Hypochondriasis0low30
Hypogalactia0low50
Hypoglycemia0low10
Hypokalemia0low10
Hyponatremia0low30
Hypopharyngeal Cancer0low10
Hypopharyngeal Neoplasms0low10
Hypopharyngeal Squamous Cell Carcinoma0low10
Hypopotassemia0low10
Hypospermatogenesis0low10
Hypotension0medium51
Hypotension, Orthostatic0low20
Hypotension, Postural0low20
Hypotension, Vascular0medium51
Hypothermia0low50
Hypothermia, Accidental0low50
Hypothyroidism0low40
Hypoxemia0low40
Hypoxia0low40
Hypoxia-Ischemia, Brain0low10
Hypoxia-Ischemia, Cerebral0low10
Hypoxic-Ischemic Encephalopathy0low10
Hypsarrhythmia0low10
Hysteria0low10
Hysteria, Dissociative0low20
Hysterical Neuroses0low10
Iatrogenic Disease0low30
Icterus0low40
Icterus Gravis Neonatorum0low10
Idiocy0medium162
Idiopathic Blepharospasm-Oromandibular Dystonia Syndrome0low20
Idiopathic Diffuse Interstitial Pulmonary Fibrosis0low10
Idiopathic Headache0low10
Idiopathic Myoclonic Epilepsy0low10
Idiopathic Orofacial Dyskinesia0low20
Idiopathic Parkinson Disease0medium193
Idiopathic Parkinson's Disease0medium193
Idiopathic Proctocolitis0low10
Idiopathic Torsion Dystonia0medium21
IgA Vasculitis0low10
IgE-Mediated Hypersensitivity0low10
Illuminating Gas Poisoning0low10
Illusions0low20
Illusions, Auditory0low20
Illusions, Kinesthetic0low20
Illusions, Tactile0low20
Illusions, Visual0low20
Immunodeficiency Syndrome, Acquired0low10
Immunologic Deficiency Syndrome, Acquired0low10
Impulse Control Disorders0medium11
Impulse-Control Disorders0medium11
Impulse-Ridden Personality0medium82
Inadequate Personality0medium82
Inadequate Sleep0low20
Inappropriate ADH Syndrome0low20
Inappropriate Prolactin Secretion0low20
Inappropriate Prolactin Secretion Syndrome0low20
Inappropriate Vasopressin Secretion Syndrome0low20
Incipient Schizophrenia0low20
Incontinentia Pigmenti Achromians0low30
Incoordination0low10
Indigestion0low10
Industrial Dermatosis0low10
Infant Botulism0low10
Infant Gynecomastia0low10
Infant, Newborn, Diseases0low10
Infantile Paralysis0low10
Infantile Severe Myoclonic Epilepsy0low10
Infantile Spasms0low10
Infarction, Cerebral0low10
Infarction, Cerebral, Left Hemisphere0low10
Infarction, Cerebral, Right Hemisphere0low10
Infarction, Left Hemisphere, Cerebral0low10
Infarction, Right Hemisphere, Cerebral0low10
Infection, Bacterial0low20
Infection, Central Nervous System, Protozoal0low10
Infection, Toxoplasma gondii0low10
Infection, Wound0low10
Infections, Bacterial0low20
Infections, Clostridium0low10
Infections, E coli0low30
Infections, Escherichia coli0low30
Infections, Meningococcal0low10
Infections, Nematode0low10
Infections, Plasmodium0low20
Infections, Protozoal, Central Nervous System0low10
Infections, Salmonella0low10
Infections, Staphylococcal0low10
Infections, Streptococcal0low10
Infectious Hepatitis0low10
Inferior Dislocation0low10
Infertility, Male0low10
Inflammation0low30
Inflammatory Bowel Disease, Ulcerative Colitis Type0low10
Inflammatory Rheumatism0low10
Injuries0low10
Injuries and Wounds0low10
Injuries, Acute Brain0low20
Injuries, Brain0low20
Injuries, Craniocerebral0low10
Injuries, Finger0low10
Injuries, Head0low10
Injuries, Spinal0low10
Injuries, Spinal Cord0low20
Injuries, Whiplash0low10
Injuries, Wounds0low10
Injury, Brain, Traumatic0low10
Injury, Ischemia-Reperfusion0low90
Injury, Myocardial Reperfusion0low20
Injury, Reperfusion0low90
Innate Inflammatory Response0low30
Insomnia0low40
Insomnia Disorder0low40
Insufficient Sleep0low20
Insufficient Sleep Syndrome0low20
Insulin Resistance0low10
Insulin Resistance Syndrome X0low10
Insulin Sensitivity0low10
Insulinoma0low60
Insuloma0low60
Intellectual Development Disorder0medium162
Intellectual Disability0medium162
Intention Tremor0medium61
Intermittent Explosive Disorder0medium11
Intermittent Tremor0medium61
Intersex Conditions0low20
Intersexuality0low20
Interstitial Cell Tumor0low20
Intervertebral Disc Displacement0low20
Intervertebral Disk Displacement0low20
Intestinal Diseases0low10
Intestinal Diseases, Parasitic0low10
Intestinal Obstruction0low20
Intestinal Pseudo-Obstruction0low10
Intestinal Pseudo-Obstruction, Idiopathic0low10
Intestinal Pseudoobstruction0low10
Intoxication, Alcoholic0low20
Intracerebral Hemorrhage0low20
Intracranial Astrocytoma0low40
Intracranial Central Nervous System Disorders0low90
Intracranial CNS Disorders0low90
Intracranial Edema0low40
Intracranial Neoplasms0medium141
Intracranial Vascular Disorders0low20
Intrahepatic Cholangiocarcinoma0low20
Intravascular Coagulation, Disseminated0low10
Intravascular Disseminated Coagulation0low10
Intravascular Hemolysis0low150
Invasiveness, Neoplasm0low20
Involuntary Movements0low10
Involuntary Quiver0medium61
Iodamoebiasis0low10
Iron Overload0low10
Ischemia0low60
Ischemia-Anoxia, Brain0low10
Ischemia-Anoxia, Cerebral0low10
Ischemia-Hypoxia, Brain0low10
Ischemia-Hypoxia, Cerebral0low10
Ischemia-Reperfusion Injury0low90
Ischemia, Cerebral0low10
Ischemia, Myocardial0low20
Ischemic Attack, Transient0low50
Ischemic Encephalopathy0low10
Ischemic Heart Disease0low20
Ischemic-Hypoxic Encephalopathy0low10
Island Cell Tumor0low80
Islet Cell Tumor0low80
Islet of Langerhans Tumor0low80
Itching0low10
Ito Syndrome0low30
Jackknife Seizures0low10
Jacksonian Seizure0low90
Jaundice0low40
Jaundice, Hemolytic0low40
Jaundice, Neonatal0low10
Joint Dislocations0low10
Joint Subluxations0low10
Juvenile Huntington Disease0low40
Juvenile Parkinson Disease0low60
Juvenile Parkinson Disease, Autosomal Dominant0low60
Juvenile Parkinson Disease, Autosomal Recessive0low60
Juvenile Parkinsonism, Autosomal Dominant0low60
Juvenile Parkinsonism, Autosomal Recessive0low60
Juvenile Pilocytic Astrocytoma0low40
Juvenile-Onset Huntington Disease0low40
Kahler Disease0low30
Kandinsky Syndrome0medium102
Kanner's Syndrome0medium11
Kaposi Disease0low10
Kaposi's Disease0low10
Keratoderma Blennorrhagicum0low10
Keratoma0low10
Keratosis0low10
Keratosis Blennorrhagica0low10
Keskushermoston sairaudet@fi0low10
Kidney Cancer0low20
Kidney Diseases0low30
Kidney Failure, Acute0low20
Kidney Insufficiency, Acute0low20
Kidney Neoplasms0low20
Kinnier-Wilson Disease0low10
Kleptomania0medium11
Klinefelter Syndrome0low10
Klinefelter Syndrome, Variants0low10
Klinefelter's Syndrome0low10
Korsakoff Psychosis0low10
Korsakoff Syndrome0low10
Kussmaul Aphasia0low10
Kussmaul's Aphasia0low10
Lack of Coordination0low10
Lactation Disorders0low50
Lambliasis0low20
Lameness, Animal0low10
Large Lymphoid Lymphoma, Diffuse0low10
Large-Cell Lymphoma, Diffuse0low10
Laryngeal Diseases0low10
Laryngeal Perichondritis0low10
Laryngeal Squamous Cell Carcinoma0low10
Larynx Diseases0low10
Lassitude0low10
Late Effects, Prenatal Exposure0low10
Late Onset Alzheimer Disease0low10
Late-Onset Huntington Disease0low40
Latent Schizophrenia0low20
Learning Disabilities0low20
Learning Disorders0low20
Learning Disorders, Adult0low20
Learning Disturbance0low20
Left Bundle-Branch Block0low10
Left Hemisphere, Cerebral Infarction0low10
Left Hemisphere, Infarction, Cerebral0low10
Left-Sided Heart Failure0low40
Lens Opacities0low20
Lenticulostriate Disorders0medium286
Leprosy0low10
Leprosy, Cutaneous0low10
Leprosy, Lepromatous0low10
Leprosy, Nodular0low10
Lethal Catatonia0low100
Leucocythaemia0low10
Leucocythemia0low10
Leukemia0low10
Leukemia L 12100low90
Leukemia L12100low90
Leukemia Model, Animal0low120
Leukemia P3880low110
Leukemia, Acute Myelogenous0low20
Leukemia, Acute Myeloid0low20
Leukemia, Acute Promyelocytic0low10
Leukemia, Basophilic, Acute0low20
Leukemia, Chronic Myelogenous0low10
Leukemia, Chronic Myeloid0low10
Leukemia, Erythroblastic, Acute0low30
Leukemia, Experimental0low120
Leukemia, Granulocytic0low10
Leukemia, Granulocytic, Chronic0low10
Leukemia, Lymphoblastic, Burkitt-Type0low20
Leukemia, Lymphocytic, L30low20
Leukemia, Lymphocytic, T Cell0low10
Leukemia, Lymphocytic, T-Cell0low10
Leukemia, Monocytic, Chronic0low10
Leukemia, Myeloblastic, Acute0low20
Leukemia, Myelocytic0low10
Leukemia, Myelocytic, Acute0low20
Leukemia, Myelocytic, Chronic0low10
Leukemia, Myelogenous0low10
Leukemia, Myelogenous, Acute0low20
Leukemia, Myelogenous, Chronic0low10
Leukemia, Myelogenous, Chronic, BCR-ABL Positive0low10
Leukemia, Myelogenous, Ph1 Positive0low10
Leukemia, Myelogenous, Ph1-Positive0low10
Leukemia, Myeloid0low10
Leukemia, Myeloid, Acute0low20
Leukemia, Myeloid, Acute, M10low20
Leukemia, Myeloid, Acute, M20low20
Leukemia, Myeloid, Acute, M30low10
Leukemia, Myeloid, Acute, M60low30
Leukemia, Myeloid, Chronic0low10
Leukemia, Myeloid, Ph1 Positive0low10
Leukemia, Myeloid, Ph1-Positive0low10
Leukemia, Myeloid, Philadelphia Positive0low10
Leukemia, Myeloid, Philadelphia-Positive0low10
Leukemia, Nonlymphoblastic, Acute0low20
Leukemia, Nonlymphocytic, Acute0low20
Leukemia, Progranulocytic0low10
Leukemia, Promyelocytic, Acute0low10
Leukemia, T-Cell0low10
Leukemias, Experimental0low120
Leukoma0low20
Lewy Body Dementia0low10
Lewy Body Disease0low10
Lewy Body Disease, Cortical0low10
Lewy Body Disease, Diffuse0low10
Lewy Body Parkinson Disease0medium193
Lewy Body Parkinson's Disease0medium193
Lewy Body Type Senile Dementia0low10
Leydig Cell Tumor0low20
Libman-Sacks Disease0low20
Lightning Attacks0low10
Limb Cramp0low10
Lingual-Facial-Buccal Dyskinesia0low10
Linguofacial Dyskinesia0low10
Liver Cancer0low70
Liver Cancer, Adult0low100
Liver Cell Carcinoma0low100
Liver Cell Carcinoma, Adult0low100
Liver Cirrhosis0low10
Liver Cirrhosis, Alcoholic0low10
Liver Diseases0low20
Liver Dysfunction0low20
Liver Fibrosis0low10
Liver Injury, Drug-Induced0low160
Liver Injury, Drug-Induced, Acute0low160
Liver Neoplasms0low70
Liver Neoplasms, Experimental0low40
Liver Steatosis0low10
Local Neoplasm Recurrence0medium11
Local Neoplasm Recurrences0medium11
Lock Jaw0low10
Lockjaw0low10
Locoregional Neoplasm Recurrence0medium11
Long Sleeper Syndrome0low30
Louis-Bar Syndrome0low10
Louping Ill Encephalitis0low10
Low Blood Pressure0medium51
Low Bone Density0low20
Low Bone Mineral Density0low20
Low Sperm Count0low10
Lung Adenocarcinoma0low20
Lung Cancer0low150
Lung Diseases0low10
Lung Injuries0low10
Lung Injury0low10
Lung Neoplasms0low150
Lupus Erythematosus Disseminatus0low20
Lupus Erythematosus, Systemic0low20
Lupus Glomerulonephritis0low10
Lupus Nephritis0low10
Luxatio Erecta0low10
Lymphatic Sarcoma0low10
Lymphocytic Leukemia, L30low20
Lymphocytic Leukemia, T-Cell0low10
Lymphoma0low30
Lymphoma, Atypical Diffuse Small Lymphoid0low10
Lymphoma, Burkitt0low20
Lymphoma, Diffuse0low10
Lymphoma, Diffuse Large-Cell0low10
Lymphoma, Diffuse, Mixed Lymphocytic-Histiocytic0low10
Lymphoma, High-Grade0low10
Lymphoma, Histiocytic0low10
Lymphoma, Histiocytic, Diffuse0low10
Lymphoma, Intermediate-Grade0low10
Lymphoma, Large B-Cell, Diffuse0low10
Lymphoma, Large Cell, Diffuse0low10
Lymphoma, Large Lymphoid, Diffuse0low10
Lymphoma, Large-Cell, Diffuse0low10
Lymphoma, Low-Grade0low10
Lymphoma, Malignant0low30
Lymphoma, Mixed0low10
Lymphoma, Mixed Cell, Diffuse0low10
Lymphoma, Mixed Lymphocytic-Histiocytic0low10
Lymphoma, Mixed Small and Large Cell, Diffuse0low10
Lymphoma, Mixed-Cell0low10
Lymphoma, Mixed-Cell, Diffuse0low10
Lymphoma, Non-Hodgkin0low10
Lymphoma, Non-Hodgkin, Familial0low10
Lymphoma, Non-Hodgkin's0low10
Lymphoma, Non-Hodgkins0low10
Lymphoma, Nonhodgkin's0low10
Lymphoma, Nonhodgkins0low10
Lymphoma, Pleomorphic0low10
Lymphoma, Small and Large Cleaved-Cell, Diffuse0low10
Lymphoma, Small Cleaved Cell, Diffuse0low10
Lymphoma, Small Cleaved-Cell, Diffuse0low10
Lymphoma, Small Non-Cleaved-Cell0low10
Lymphoma, Small Noncleaved-Cell0low10
Lymphoma, T-Cell0low10
Lymphoma, Undifferentiated0low10
Lymphoma, Undifferentiated, Diffuse0low10
Lymphosarcoma0low10
M3 ANLL0low10
Macropsia0low20
Maculopapular Drug Eruption0low30
Maculopapular Exanthem0low30
Major Depressive Disorder0medium121
Maladie du systu00E8me nerveux central@fr0low10
Malaria0low20
Malattie del sistema nervoso centrale@it0low10
Male Breast Enlargement0low10
Malignancy0low190
Malignant Epithelial Neoplasms0low50
Malignant Glioma0low140
Malignant Hyperpyrexia0low40
Malignant Hyperthermia0low40
Malignant Melanoma0low50
Malignant Neoplasm of Breast0medium122
Malignant Neoplasms0low190
Malignant Neoplasms, Brain0medium141
Malignant Primary Brain Neoplasms0medium141
Malignant Primary Brain Tumors0medium141
Malignant Tumor of Breast0medium122
Malignant Tumor of Urinary Bladder0low10
Mammary Cancer0medium122
Mammary Carcinoma, Animal0low10
Mammary Carcinoma, Human0medium122
Mammary Neoplasm, Human0medium122
Mammary Neoplasms0low10
Mammary Neoplasms, Animal0low10
Mammary Neoplasms, Experimental0low10
Mammary Neoplasms, Human0medium122
Mandibular Micrognathia0low10
Mandibular Micrognathism0low10
Manic Depression0medium352
Manic Disorder0medium352
Manic-Depressive Psychosis0medium352
Manifestations, Neurologic0low30
Manifestations, Neurological0low30
Mar (X) Syndrome0low10
Marchiafava-Micheli Syndrome0low10
Marginal Ulcer0low20
Marker X Syndrome0low10
Marsh Fever0low20
Martin-Bell Syndrome0low10
Masochism0low10
Masseter Muscle Spasm0low10
Masseter Spasm0low10
Massive Tremor0medium61
Mast-Cell Sarcoma0low10
Mastocytoma, Malignant0low10
Maturity-Onset Diabetes0low10
Maturity-Onset Diabetes Mellitus0low10
Mechanical Allodynia0low20
Mechanical Hyperalgesia0low20
Medically Unexplained Syndrome0low10
Medically Unexplained Syndromes0low10
Medication-Induced Dyskinesia0low210
Meige Syndrome0low20
Melancholia0medium371
Melancholia, Involutional0medium121
Melanism0low10
Melanoma0low50
Melanoma, B160low20
Melanoma, Cloudman S910low20
Melanoma, Experimental0low20
Melanoma, Harding-Passey0low20
Melanomas, Experimental0low20
Melanosis0low10
Melasma0low10
Mendelson Syndrome0low10
Mendelson's Syndrome0low10
Meniere Disease0low10
Meniere's Disease0low10
Meniere's Syndrome0low10
Meningeal Plague0low10
Meningococcal Disease0low10
Meningococcal Infections0low10
Meningoencephalitis0low10
Meningoencephalitis, Protozoal0low10
Meniscitis0medium11
Menopause0low40
Mental Deficiency0medium162
Mental Disorders0medium998
Mental Disorders, Organic0medium102
Mental Disorders, Severe0medium998
Mental Illness0medium998
Mental Retardation0medium162
Mental Retardation, Psychosocial0medium162
Mental Retardation, X-Linked, Associated With Fragile Site Fraxe0low10
Mental Retardation, X-Linked, Associated With Marxq280low10
Mermaid Malformation0low10
Mermaid Syndrome0low10
Metabolic Acidosis0low20
Metabolic Bone Diseases0low20
Metabolic Cardiovascular Syndrome0low10
Metabolic Diseases0low20
Metabolic Syndrome0low10
Metabolic Syndrome X0low10
Metabolic X Syndrome0low10
Metamorphopsia0low20
Metastase0medium21
Metastases, Neoplasm0medium21
Metastasis0medium21
Metastasis, Neoplasm0medium21
Microglossia0low10
Micrognathia0low10
Micrognathism0low10
Micropsia0low20
Migraine0low20
Migraine Disorders0low20
Migraine Headache0low20
Migraine Variant0low20
Milk-Alkali Syndrome0low10
Mitochondrial Diseases0low10
Mitochondrial Disorders0low10
Mitochondrial Electron Transport Chain Deficiencies0low10
Mitochondrial Respiratory Chain Deficiencies0low10
Mixed Glioma0low140
Mixed Small and Large Cell Lymphoma, Diffuse0low10
Mixed-Cell Lymphoma0low10
Mixed-Cell Lymphoma, Diffuse0low10
MODY0low10
Moniliasis0low20
Moniliasis, Oral0low10
Monocytic Leukemia, Chronic0low10
Monosomy, Partial0low10
Mood Disorders, Psychotic0low10
Moral Injury0low10
Morbilliform Drug Reaction0low30
Morbilliform Exanthem0low30
Morgellon's0low20
Morgellons0low20
Morgellons Disease0low20
Morgellons Syndrome0low20
Mosaic Trisomy 13 Syndrome0low10
Motion Sickness0low20
Motor or Vocal Tic Disorder, Chronic0low10
Motor Tic Disorders0low10
Movement Disorder Syndromes0medium4610
Movement Disorders0medium4610
Moya-Moya Disease0low10
Moyamoya Disease0low10
Moyamoya Disease, Classic0low10
Moyamoya Disease, Primary0low10
Moyamoya Disease, Secondary0low10
Moyamoya Syndrome0low10
MPTP-Induced Experimental Parkinsonism0low60
MS (Multiple Sclerosis)0low10
Mu00E9niu00E8re Disease0low10
Mu00E9niu00E8re's Disease0low10
Mu00E9niu00E8re's Vertigo0low10
Mucoviscidosis0low30
Multiple Abnormalities0low10
Multiple Head Injuries0low10
Multiple Identity Disorder0low10
Multiple Motor and Vocal Tic Disorder, Combined0medium72
Multiple Myeloma0low30
Multiple Personalities0low10
Multiple Personality Disorder0low10
Multiple Sclerosis0low10
Multiple Sclerosis, Acute Fulminating0low10
Muscle Contraction0medium551
Muscle Cramp0low10
Muscle Disorders0low20
Muscle Dystonia0low60
Muscle Relaxation0low60
Muscle Rigidity0low10
Muscle Spasm0low30
Muscular Cramp0low10
Muscular Diseases0low20
Muscular Spasm0low30
Musculoskeletal Abnormalities0low10
Mutism0low10
Mutism, Conversion0low10
Mutism, Elective0low10
Mutism, Organic0low10
Mutism, Selective0low10
Mutism, Voluntary0low10
Myeloblastic Leukemia, Acute0low20
Myelocytic Leukemia0low10
Myelocytic Leukemia, Acute0low20
Myelocytic Leukemia, Chronic0low10
Myelogenous Leukemia0low10
Myelogenous Leukemia, Acute0low20
Myelogenous Leukemia, Chronic0low10
Myelogenous Leukemia, Ph1-Positive0low10
Myeloid Leukemia0low10
Myeloid Leukemia, Acute0low20
Myeloid Leukemia, Acute, M10low20
Myeloid Leukemia, Acute, M20low20
Myeloid Leukemia, Acute, M30low10
Myeloid Leukemia, Acute, M60low30
Myeloid Leukemia, Chronic0low10
Myeloid Leukemia, Ph1-Positive0low10
Myeloid Leukemia, Philadelphia-Positive0low10
Myeloma-Multiple0low30
Myeloma, Multiple0low30
Myeloma, Plasma-Cell0low30
Myelomatosis0low30
Myelopathy, Traumatic0low20
Myocardial Diseases0low30
Myocardial Diseases, Primary0low30
Myocardial Diseases, Secondary0low30
Myocardial Failure0low40
Myocardial Infarct0low60
Myocardial Infarction0low60
Myocardial Ischemia0low20
Myocardial Ischemic Reperfusion Injury0low20
Myocardial Reperfusion Injury0low20
Myocardiopathies0low30
Myocarditis0low20
Myoclonic Absence Epilepsy0low10
Myoclonic Astatic Epilepsy0low10
Myoclonic Encephalopathy0low10
Myoclonic Epilepsy0low10
Myoclonic Epilepsy, Benign Infantile0low10
Myoclonic Epilepsy, Early Childhood0low10
Myoclonic Epilepsy, Infantile0low10
Myoclonic Epilepsy, Infantile, Benign0low10
Myoclonic Epilepsy, Infantile, Severe0low10
Myoclonic Epilepsy, Severe Infantile0low10
Myoclonic Epilepsy, Severe, Of Infancy0low10
Myoclonic Jerk0low10
Myoclonic Jerking0low10
Myoclonic Seizure0low90
Myoclonic Seizure Disorder0low10
Myoclonic Seizures0low90
Myoclonus0low10
Myoclonus Simplex0low10
Myoclonus, Action0low10
Myoclonus, Eyelid0low10
Myoclonus, Intention0low10
Myoclonus, Lower Extremity0low10
Myoclonus, Nocturnal0low10
Myoclonus, Oculopalatal0low10
Myoclonus, Palatal0low10
Myoclonus, Segmental0low10
Myoclonus, Sleep0low10
Myoclonus, Upper Extremity0low10
Myopathic Conditions0low20
Myopathic Ophthalmopathy0low10
Myopathies0low20
Myxedema0low10
Naegleria fowleri Infection0low10
Naegleria fowleri Meningoencephalitis0low10
Narcissistic Personality Disorder0medium82
Narcolepsy0low10
Narcolepsy-Cataplexy Syndrome0low10
Narcoleptic Syndrome0low10
Nasal Catarrh0low10
Nasopharyngeal Cancer0low10
Nasopharyngeal Carcinoma0low10
Nasopharyngeal Neoplasms0low10
Nasopharynx Cancer0low10
Nasopharynx Neoplasms0low10
Nausea0low60
Near-Death Experience0low10
Neck Cancer0low10
Neck Neoplasm0low10
Neck Neoplasms0low10
Necrosis0low60
Nematode Infections0low10
nemoci centru00E1lnu00EDho nervovu00E9ho systu00E9mu@cs0low10
Neonatal Diseases0low10
Neonatal Jaundice0low10
Neoplasia0low190
Neoplasm0low190
Neoplasm Invasion0low20
Neoplasm Invasiveness0low20
Neoplasm Metastases0medium21
Neoplasm Metastasis0medium21
Neoplasm Recurrence, Local0medium11
Neoplasm Recurrence, Locoregional0medium11
Neoplasm Recurrences, Local0medium11
Neoplasms0low190
Neoplasms, Adrenal Gland0low60
Neoplasms, Benign0low190
Neoplasms, Bile Duct0low20
Neoplasms, Bladder0low10
Neoplasms, Bone0low20
Neoplasms, Bone Marrow0low10
Neoplasms, Brain0medium141
Neoplasms, Brain, Benign0medium141
Neoplasms, Brain, Malignant0medium141
Neoplasms, Brain, Primary0medium141
Neoplasms, Breast0medium122
Neoplasms, Central Nervous System0low10
Neoplasms, Colonic0low50
Neoplasms, Colorectal0low10
Neoplasms, Experimental0low190
Neoplasms, Experimental Liver0low40
Neoplasms, Experimental Mammary0low10
Neoplasms, Gastric0low20
Neoplasms, Head0low10
Neoplasms, Head and Neck0low10
Neoplasms, Hepatic0low70
Neoplasms, Hypopharyngeal0low10
Neoplasms, Intracranial0medium141
Neoplasms, Kidney0low20
Neoplasms, Liver0low70
Neoplasms, Lung0low150
Neoplasms, Malignant Epithelial0low50
Neoplasms, Mammary0low10
Neoplasms, Nasopharyngeal0low10
Neoplasms, Neck0low10
Neoplasms, Ovarian0low20
Neoplasms, Pancreatic0low140
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Neoplasms, Pulmonary0low150
Neoplasms, Radiation-Induced0low10
Neoplasms, Skin0low60
Neoplasms, Stomach0low20
Neoplasms, Thymic0low10
Neoplasms, Thymus0low10
Neoplasms, Thyroid0low20
Neoplasms, Upper Aerodigestive Tract0low10
Neoplastic Cell Transformation0low40
Neoplastic Transformation, Cell0low40
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Nephritis, Lupus0low10
Nephroid Carcinoma0low10
Nerve Pain0medium11
Nervous System Diseases0low30
Nervous System Disorders0low30
Nervous System Poisoning0low10
Nesidioblastoma0low80
Neuralgia0medium11
Neuralgia, Atypical0medium11
Neuralgia, Iliohypogastric Nerve0medium11
Neuralgia, Ilioinguinal0medium11
Neuralgia, Perineal0medium11
Neuralgia, Stump0medium11
Neuralgia, Supraorbital0medium11
Neuralgia, Vidian0medium11
Neurasthenia0low20
Neurasthenic Neuroses0low20
Neurilemmoma0low10
Neurilemoma0low10
Neurinoma0low10
Neuroaxonal Dystrophy, Juvenile-Onset0low10
Neuroblastoma0low80
Neurocirculatory Asthenia0low10
Neurocognitive Disorders0medium102
Neurodegeneration With Brain Iron Accumulation 10low10
Neurodegeneration with Brain Iron Accumulation Type 10low10
Neurodynia0medium11
Neurohepatic Degeneration0low10
Neuroleptic Malignant Syndrome0low190
Neuroleptic-Induced Neuroleptic Malignant Syndrome0low190
Neuroleptic-Malignant Syndrome, Neuroleptic Induced0low190
Neurologic Deficits0low30
Neurologic Disorders0low30
Neurologic Dysfunction0low30
Neurologic Findings0low30
Neurologic Manifestation0low30
Neurologic Manifestations0low30
Neurologic Signs0low30
Neurologic Signs and Symptoms0low30
Neurologic Symptoms0low30
Neurologic Voice Disorder0low10
Neurological Disorders0low30
Neurological Manifestations0low30
Neuropathic Pain0medium11
Neuroretinitis0medium11
Neuroses0medium212
Neuroses, Anxiety0medium264
Neuroses, Neurasthenic0low20
Neuroses, Phobic0low30
Neuroses, Post-Traumatic0low10
Neuroses, Posttraumatic0low10
Neurosis, Depressive0medium371
Neurosis, Hypochondriacal0low30
Neurosis, Obsessive-Compulsive0low90
Neurotic Disorders0medium212
Neurotoxic Disorders0low10
Neurotoxicity Syndromes0low10
Neurotoxin Diseases0low10
Neurotoxin Disorders0low10
Newborn Gynecomastia0low10
NIDDM0low10
Niemann-Pick Disease0low10
Niemann-Pick Diseases0low10
NMS (Neuroleptic Malignant Syndrome)0low190
Nociceptive Pain0low10
Nodding Spasm0low10
Non-Epileptic Seizure0low90
Non-Epileptic Seizures0low90
Non-Hodgkin Lymphoma0low10
Non-Hodgkin's Lymphoma0low10
Non-Small Cell Lung Cancer0low30
Non-Small Cell Lung Carcinoma0low30
Non-Small-Cell Lung Carcinoma0low30
Nonepileptic Seizure0low90
Nonepileptic Seizures0low90
Noninsulin-Dependent Diabetes Mellitus0low10
Nonketotic Hyperglycemic Coma0low10
Nonketotic Hyperosmolar Coma0low10
Nonlymphoblastic Leukemia, Acute0low20
Nonlymphocytic Leukemia, Acute0low20
Nonorganic Insomnia0low40
Nonpsychotic Organic Brain Syndrome0medium102
Nonsmall Cell Lung Cancer0low30
Nuchal Rigidity0low10
Oat Cell Carcinoma0low20
Obesity0medium31
Obsessive-Compulsive Disorder0low90
Obstructive Hydrocephalus0low10
Occipital Lobe Epilepsy0low10
Occipital Region Trauma0low10
Occipital Trauma0low10
Occupational Dermatitis0low10
Occupational Diseases0low30
Occupational Illnesses0low30
Ocular Headache0low30
Ocular Toxoplasmosis0low10
Odontalgia0low10
Oesophageal Squamous Cell Carcinoma0low10
Oligoasthenoteratozoospermia0low10
Oligoastrocytoma, Mixed0low40
Oligospermia0low10
Oligozoospermia0low10
Oncogenesis0low10
Open Head Injury0low10
Ophthalmopathies, Thyroid-Associated0low10
Ophthalmopathy, Infiltrative0low10
Ophthalmopathy, Thyroid-Associated0low10
Oppenheim-Ziehen Disease0medium21
Oral Cavity Squamous Cell Carcinoma0low10
Oral Dyskinesia0low10
Oral Manifestations0low10
Oral Squamous Cell Carcinoma0low10
Oral Squamous Cell Carcinomas0low10
Oral Tongue Squamous Cell Carcinoma0low10
Oral-Facial Dyskinesia0low10
Organic Brain Syndrome, Nonpsychotic0medium102
Organic Catatonic Disorder0low100
Organic Mental Disorders0medium102
Organic Mental Disorders, Psychotic0medium102
Organic Mental Disorders, Substance-Induced0medium151
Organophosphate Poisoning0low10
Organophosphorus Poisoning0low10
Organothiophosphate Poisoning0low10
Organothiophosphonate Poisoning0low10
Orgasmic Disorder0low10
Orofacial Dyskinesia0low10
Oropharyngeal Dysphagia0medium21
Oropharyngeal Squamous Cell Carcinoma0low10
Orthostatic Headache0low30
Orthostatic Hypotension0low20
Osteoarthritis0low10
Osteoarthrosis0low10
Osteoarthrosis Deformans0low10
Osteoblastoma0low10
Osteochondritis0medium11
Osteoclastic Bone Loss0low50
Osteogenic Sarcoma0low20
Osteoma, Giant Osteoid0low10
Osteopenia0low20
Osteoporosis0low20
Osteoporosis, Age-Related0low20
Osteoporosis, Involutional0low20
Osteoporosis, Post-Traumatic0low20
Osteoporosis, Senile0low20
Osteosarcoma0low20
Osteosarcoma Tumor0low20
Ostium Secundum Atrial Septal Defect0low10
Otogenic Vertigo0low10
Ovarian Cancer0low20
Ovarian Diseases0low10
Ovarian Neoplasms0low20
Ovary Cancer0low20
Ovary Neoplasms0low20
Overinclusion0low40
Overweight0low10
Oxidative Phosphorylation Deficiencies0low10
Oxygen Deficiency0low40
P388D(1) Leukemia0low110
Pain0low50
Pain Disorder0low10
Pain, Burning0low50
Pain, Crushing0low50
Pain, Intractable0low30
Pain, Migratory0low50
Pain, Radiating0low50
Pain, Splitting0low50
Palmoplantaris Pustulosis0low10
Palsy0low20
Paludism0low20
Panayiotopoulos Syndrome0low10
Pancreas Cancer0low140
Pancreas Neoplasms0low140
Pancreatic Cancer0low140
Pancreatic Cystic Fibrosis0low30
Pancreatic Duct Cell Carcinoma0low10
Pancreatic Ductal Carcinoma0low10
Pancreatic Islet Cell Tumors0low80
Pancreatic Neoplasms0low140
Pancreatic Parenchyma with Edema0low20
Pancreatic Parenchymal Edema0low20
Pancreatitis0low20
Pancreatitis, Acute0low20
Pancreatitis, Acute Edematous0low20
Pantothenate Kinase-Associated Neurodegeneration0low10
Papillary Renal Cell Carcinoma0low10
Paracousis0low10
Paracusis0low10
Paralysis0low20
Paralysis Agitans0medium193
Paralytic Ileus0low10
Paranoia0medium356
Paranoid Disorders0medium356
Paranoid Psychoses0medium356
Paranoid Schizophrenia0medium287
Paraphrenia, Involutional0medium121
Parasite Infections0low10
Parasitic Diseases0low10
Parasitic Infections0low10
Parasitic Intestinal Diseases0low10
Parenterally-Transmitted Non-A, Non-B Hepatitis0low10
Parietal Region Trauma0low10
Parkinson Disease0medium193
Parkinson Disease 20low60
Parkinson Disease 2, Autosomal Recessive Juvenile0low60
Parkinson Disease Autosomal Recessive, Early Onset0low60
Parkinson Disease, Autosomal Dominant. Juvenile0low60
Parkinson Disease, Experimental0low60
Parkinson Disease, Familial, Autosomal Recessive0low60
Parkinson Disease, Idiopathic0medium193
Parkinson Disease, Juvenile0low60
Parkinson Disease, Juvenile, Autosomal Dominant0low60
Parkinson Disease, Juvenile, Autosomal Recessive0low60
Parkinson Disease, Secondary0medium202
Parkinson Disease, Secondary Vascular0medium202
Parkinson Disease, Symptomatic0medium202
Parkinson's Disease0medium193
Parkinson's Disease, Idiopathic0medium193
Parkinson's Disease, Lewy Body0medium193
Parkinsonian Diseases0low60
Parkinsonian Disorders0low60
Parkinsonian Syndrome0low60
Parkinsonian Syndromes0low60
Parkinsonism0low60
Parkinsonism, Early Onset, with Diurnal Fluctuation0low60
Parkinsonism, Early-Onset, With Diurnal Fluctuation0low60
Parkinsonism, Experimental0low60
Parkinsonism, Juvenile0low60
Parkinsonism, Juvenile, Autosomal Dominant0low60
Parkinsonism, Juvenile, Autosomal Recessive0low60
Parkinsonism, Secondary0medium202
Parkinsonism, Symptomatic0medium202
Paroxysmal Cold Hemoglobinuria0low10
Paroxysmal Dyskinesias0low80
Paroxysmal Hemoglobinuria0low10
Paroxysmal Hemoglobinuria, Cold0low10
Paroxysmal Hemoglobinuria, Nocturnal0low10
Paroxysmal Nerve Pain0medium11
Paroxysmal Nocturnal Hemoglobinuria0low10
Paroxysmal Sleep0low10
Partial Epilepsy0low10
Partial Fetal Alcohol Syndrome0low10
Partial Monosomy0low10
Partial Seizure0low90
Partial Seizure Disorder0low10
Partial Seizures0low90
Partial Seizures, Simple, Consciousness Preserved0low10
Passive Tremor0medium61
Patau Syndrome0low10
Patau's Syndrome0low10
Pathologic Angiogenesis0low10
Pathologic Neovascularization0low10
PBGD Deficiency0low10
Penile Fibromatosis0medium21
Penile Induration0medium21
Peptic Ulcer0low20
Pericarditis0low10
Perinatal Subarachnoid Hemorrhage0low20
Periorbital Headache0low30
Peripancreatic Fat Necrosis0low20
Peritonitis0low10
Pernicious Vomiting of Pregnancy0low10
Persistent Ostium Primum0low10
Persistent Tremor0medium61
Personality Disorder, Antisocial0medium21
Personality Disorder, Borderline0medium42
Personality Disorder, Schizotypal0low20
Personality Disorders0medium82
Pertussis0low10
Pervasive Child Development Disorders0low10
Pervasive Development Disorders0low10
Petechiae0low10
Petit Mal Convulsion0low90
Peyronie Disease0medium21
Peyronie's Disease0medium21
Phacomatosis, Bourneville0low10
Phakomatosis, Bourneville0low10
Pheochromocytoma0low50
Pheochromocytoma, Extra-Adrenal0low50
Phlegmon0low10
Phobia, School0low30
Phobias0low30
Phobic Disorders0low30
Phobic Neuroses0low30
Phocomelia0low10
Photodermatitis0low20
Photosensitivity Disorders0low20
Photosensitization0low20
Phototoxic Contact Dermatitis0low30
Phototoxic Dermatitis0low30
Phototoxicity0low30
Phycomycosis0low10
Physiological Neonatal Jaundice0low10
Pigmentary Pallidal Atrophy0low10
Pigmentary Pallidal Degeneration0low10
Pigmentation Disorders0low30
Pill Rolling Tremor0medium61
Pilocytic Astrocytoma0low40
Pituitary Adenoma0low160
Pituitary Cancer0low160
Pituitary Carcinoma0low160
Pituitary Neoplasms0low160
Pituitary Tumors0low160
PKAN Neuroaxonal Dystrophy, Juvenile-Onset0low10
Plague0low10
Plasma Cell Myeloma0low30
Plasma Cell Tumor0low10
Plasmacytoma0low10
Plasmocytoma0low10
Plasmodium Infections0low20
Plastic Induration of the Penis0medium21
Plegia0low20
Pleuropericarditis0low10
Pneumonia, Aspiration0low10
Pneumonic Plague0low10
Poisoning0low80
Poisoning, Blood0low20
Poisoning, Carbon Monoxide0low10
Poisoning, Carbon Tetrachloride0low30
Poisoning, CCl40low30
Poisoning, Illuminating Gas0low10
Poisoning, Nervous System0low10
Polio0low10
Polio Encephalitis0low10
Poliomyelitis0low10
Poliomyelitis Infection0low10
Poliomyelitis, Acute0low10
Poliomyelitis, Nonpoliovirus0low10
Poliomyelitis, Preparalytic0low10
Polyarthritis Rheumatica0low10
Polymyoclonus0low10
Porphobilinogen Deaminase Deficiency0low10
Porphyria0low20
Porphyria, Acute Intermittent0low10
Porphyria, Swedish Type0low10
Porphyrias0low20
Porphyrin Disorder0low20
Portal-Systemic Encephalopathy0low10
Portosystemic Encephalopathy0low10
Post Traumatic Stress Disorder0low10
Post-Traumatic Hydrocephalus0low10
Post-Traumatic Myelopathy0low20
Post-Traumatic Stress Disorders0low10
Post-Traumatic Tic Disorder0low10
Postabsorptive Hypoglycemia0low10
Posterior Choroidal Artery Infarction0low10
Posterior Circulation Transient Ischemic Attack0low50
Posterior Fascicular Block0low10
Postoperative Complications0low20
Postpartum Amenorrhea0low20
Postprandial Hyperglycemia0medium21
Postprandial Hypoglycemia0low10
Posttraumatic Stress Disorders0low10
Powassan Encephalitis0low10
Powassan Virus Disease0low10
Predisposition, Genetic0low10
Pregnancy0low620
Pregnancy Complications0low60
Prenatal Exposure Delayed Effects0low10
Prescription Drug Abuse0medium151
Presenile Alzheimer Dementia0low10
Presyncope0low10
Primary Amebic Meningoencephalitis0low10
Primary Brain Neoplasms0medium141
Primary Central Nervous System Neoplasm0low10
Primary Central Nervous System Neoplasms0low10
Primary Hyperthyroidism0low20
Primary Hypothyroidism0low40
Primary Insomnia0low40
Primary Malignant Brain Neoplasms0medium141
Primary Malignant Brain Tumors0medium141
Primary Myocardial Diseases0low30
Primary Parkinsonism0medium193
Primary Peritonitis0low10
Primary Senile Degenerative Dementia0low10
Progranulocytic Leukemia0low10
Progressive Chorea, Chronic Hereditary (Huntington)0low40
Progressive Chorea, Hereditary, Chronic (Huntington)0low40
Progressive Intracranial Occlusive Arteropathy (Moyamoya)0low10
Progressive Lenticular Degeneration0low10
Progressive Torsion Spasm0medium21
Prolactin Hypersecretion Syndrome0low20
Prolactin, Inappropriate Secretion0low20
Prolapsed Disc0low20
Prolapsed Disk0low20
Promyelocytic Leukemia, Acute0low10
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Cancer0low20
Prostatic Neoplasms0low20
Proteinuria0low10
Protozoal Infections, Central Nervous System0low10
Protozoal Infections, Cerebral0low10
Protozoal Meningoencephalitis0low10
Pruritis0low10
Pruritus0low10
Pseudo-Obstruction, Intestinal0low10
Pseudoakathisia0low20
Pseudoaphakia0low20
Pseudocoma0low60
Pseudohermaphroditism0low20
Pseudointestinal Obstruction Syndrome0low10
Pseudomembranous Colitis0low10
Pseudomembranous Enteritis0low10
Pseudomembranous Enterocolitis0low10
Pseudoneurotic Schizophrenia0low20
Pseudoobstructive Syndrome0low10
Pseudopsychopathic Schizophrenia0low20
Pseudosclerosis0low10
Psoriasis0low10
Psychiatric Diagnosis0medium998
Psychiatric Diseases0medium998
Psychiatric Disorders0medium998
Psychiatric Illness0medium998
Psychogenic Headache0low10
Psychomotor Agitation0low30
Psychomotor Disorders0low10
Psychomotor Disorders, Developmental0low10
Psychomotor Hyperactivity0low30
Psychomotor Impairment0low10
Psychomotor Restlessness0low30
Psychoneuroses0medium212
Psychopathic Personality0medium21
Psychophysiologic Disorders0medium81
Psychophysiological Disorders0medium81
Psychophysiological Insomnia0low40
Psychoses0medium1008
Psychoses, Affective0low10
Psychoses, Alcoholic0medium61
Psychoses, Drug0medium101
Psychoses, Manic-Depressive0medium352
Psychoses, Paranoid0medium356
Psychoses, Substance-Induced0medium101
Psychoses, Toxic0medium101
Psychoses, Traumatic0medium102
Psychosexual Disorders0low10
Psychosexual Dysfunctions0low10
Psychosis0medium1008
Psychosis, Brief Reactive0medium1008
Psychosis, Involutional0medium121
Psychosis, Manic-Depressive0medium352
Psychosomatic Disorders0medium81
Psychotic Affective Disorders0low10
Psychotic Mood Disorders0low10
PT-NANBH0low10
Ptosis, Eyelid0low20
PTSD0low10
Puerperal Disorders0low50
Pulmonary Cancer0low150
Pulmonary Cystic Fibrosis0low30
Pulmonary Disease0low10
Pulmonary Diseases0low10
Pulmonary Edema0low10
Pulmonary Edemas0low10
Pulmonary Fibroses0low10
Pulmonary Fibrosis0low10
Pulmonary Hypertension0low20
Pulmonary Injury0low10
Pulmonary Neoplasms0low150
Pulmonic Plague0low10
Pulsatile Tinnitus0low10
Purpura0low10
Pustular Psoriasis of Palms and Soles0low10
Pustulosis of Palms and Soles0low10
Pustulosis Palmaris et Plantaris0low10
Pyaemia0low20
Pyemia0low20
Pyohemia0low20
Pyrexia0low50
Quincke's Edema0low10
Radiation-Induced Cancer0low10
Radiation-Induced Neoplasms0low10
Ramsay Hunt Paralysis Syndrome0low60
Reactive Disorders0low60
Reactive Hypoglycemia0low10
Reaven Syndrome X0low10
Rebound Insomnia0low40
Recrudescence0medium135
Recurrence0medium135
Recurrence, Local Neoplasm0medium11
Recurrence, Locoregional Neoplasm0medium11
Recurrences, Local Neoplasm0medium11
Refractory Pain0low30
Relapse0medium135
REM Sleep Deprivation0low20
Remission, Spontaneous0low20
Remittent Fever0low20
Renal Artery Obstruction0low10
Renal Artery Stenosis0low10
Renal Cancer0low20
Renal Carcinoma0low10
Renal Cell Cancer0low10
Renal Cell Carcinoma0low10
Renal Cell Carcinoma, Papillary0low10
Renal Collecting Duct Carcinoma0low10
Renal Failure, Acute0low20
Renal Insufficiency, Acute0low20
Renal Neoplasms0low20
Reperfusion Damage0low90
Reperfusion Injury0low90
Reperfusion Injury, Myocardial0low20
Research-Related Injuries0low10
Respiration Disorders0low10
Respiratory Chain Deficiencies, Mitochondrial0low10
Rest Tremor0medium61
Resting Tremor0medium61
Restlessness0low30
Retardation, Mental0medium162
Reticulolymphosarcoma0low30
Reticulosarcoma0low10
Reticulum Cell Sarcoma0low10
Reticulum-Cell Sarcoma0low10
Retinal Diseases0low10
Retinitis0medium11
Retro-Ocular Headache0low30
Rhabdomyolysis0low10
Rheumatic Arthritis0low10
Rheumatic Chorea0low80
Rheumatic Fever0low10
Rheumatism, Acute Articular0low10
Rheumatism, Articular, Acute0low10
Rheumatoid Arthritis0low10
Rhinencephalic Epilepsy0low10
Rhinitis0low10
Rhinolalia0medium21
Right Bundle-Branch Block0low10
Right Hemisphere, Cerebral Infarction0low10
Right Hemisphere, Infarction, Cerebral0low10
Right-Sided Heart Failure0low40
Rigidity, Muscular0low10
Ringing-Buzzing-Tinnitus0low10
Russian Spring-Summer Encephalitis0low10
SAH (Subarachnoid Hemorrhage)0low20
Salaam Attacks0low10
Salaam Seizures0low10
Salivary Gland Diseases0low10
Salmonella Infections0low10
Salmonella Infections, Animal0low10
Salmonellosis0low10
Sappinia diploidea Meningoencephalitis0low10
Sarcoma, Germinoblastic0low30
Sarcoma, Lymphatic0low10
Sarcoma, Mast-Cell0low10
Sarcoma, Osteogenic0low20
Sarcoma, Reticulum-Cell0low10
Sarcomatoid Renal Cell Carcinoma0low10
SARS Coronavirus 2 Infection0low10
SARS-CoV-2 Infection0low10
Saturnine Tremor0medium61
Schamberg Disease0low30
Schamberg's Disease0low30
Schizoaffective Disorder0medium1008
Schizophrenia0medium35997
Schizophrenia, Borderline0low20
Schizophrenia, Catatonic0low40
Schizophrenia, Childhood0medium103
Schizophrenia, Disorganized0medium21
Schizophrenia, Hebephrenic0medium21
Schizophrenia, Latent0low20
Schizophrenia, Paranoid0medium287
Schizophrenia, Pseudoneurotic0low20
Schizophrenic Disorders0medium35997
Schizophreniform Catatonia0low100
Schizophreniform Disorders0medium1008
Schizotypal Personality Disorder0low20
Scholastic Skills Development Disorders0low20
Schwannoma0low10
Schwannomatosis, Plexiform0low10
Schwartz-Bartter Syndrome0low20
Sclerosis Tuberosa0low10
Sclerosis, Disseminated0low10
Scoliosis0low10
Sea Sickness0low20
Seasickness0low20
Secondary Hypothyroidism0low40
Secondary Insomnia0low40
Secondary Myocardial Diseases0low30
Secondary Parkinsonism0medium202
Secondary Peritonitis0low10
Secondary Vascular Parkinson Disease0medium202
Seizure0low90
Seizure Disorder0medium102
Seizure Disorder, Focal0low10
Seizure Disorder, Partial0low10
Seizures0low90
Seizures, Auditory0low90
Seizures, Clonic0low90
Seizures, Convulsive0low90
Seizures, Epileptic0low90
Seizures, Focal0low90
Seizures, Generalized0low90
Seizures, Gustatory0low90
Seizures, Motor0low90
Seizures, Olfactory0low90
Seizures, Sensory0low90
Seizures, Somatosensory0low90
Seizures, Tonic0low90
Seizures, Tonic-Clonic0low90
Seizures, Vertiginous0low90
Seizures, Vestibular0low90
Seizures, Visual0low90
Selective Mutism0low10
Self Mutilating Behavior0low40
Self Mutilation0low40
Senile Chorea0low80
Senile Dementia, Acute Confusional0low10
Senile Dementia, Alzheimer Type0low10
Senile Osteoporosis0low20
Senile Paranoid Dementia0medium101
Senile Tremor0medium61
Sensitivity and Specificity0low40
Sensitivity, Contact0low20
Sepsis0low20
Septicemia0low20
Septicemic Plague0low10
Severe Infantile Myoclonic Epilepsy0low10
Severe Jaundice in Neonate0low10
Severe Jaundice in Newborn0low10
Severe Myoclonic Epilepsy Of Infancy0low10
Severe Myoclonic Epilepsy, Infantile0low10
Severe Sepsis0low20
Sex Development Disorders0low20
Sex Differentiation Disorders0low20
Sex Disorders0low10
Sexual Arousal Disorder0low10
Sexual Aversion Disorder0low10
Sexual Development Disorders0low20
Sexual Differentiation Disorders0low20
Sexual Disorders, Physiological0low10
Sexual Dysfunction, Physiological0low10
Sexual Dysfunctions, Physiological0low10
Sexual Dysfunctions, Psychological0low10
Sexual Masochism0low10
Sharp Headache0low30
Short Sleep Phenotype0low30
Short Sleeper Syndrome0low30
SIADH0low20
Sick Headache0low20
Sickle Cell Anemia0medium41
Sickle Cell Disease0medium41
Sickle Cell Disorders0medium41
Sickling Disorder Due to Hemoglobin S0medium41
Side Effects of Drugs0low60
Simple Partial Seizures0low10
Single Seizure0low90
Sirenomelia0low10
Sirenomelia Sequence0low10
Sirenomelus0low10
Skin and Subcutaneous Tissue Disorders0low50
Skin Cancer0low60
Skin Diseases0low50
Skin Neoplasms0low60
Sleep Debt0low20
Sleep Deprivation0low20
Sleep Disorders0low30
Sleep Fragmentation0low20
Sleep Initiation and Maintenance Disorders0low40
Sleep Initiation Dysfunction0low40
Sleep Insufficiency0low20
Sleep Wake Disorders0low30
Sleep-Related Neurogenic Tachypnea0low30
Sleeplessness0low40
Slipped Disc0low20
Slipped Disk0low20
Small Cell Carcinoma0low20
Small Cleaved-Cell Lymphoma, Diffuse0low10
Small Non-Cleaved-Cell Lymphoma0low10
Small Noncleaved-Cell Lymphoma0low10
Sociopathic Personality0medium21
Somatic Pain0low10
Somatization Disorder0low10
Somatoform Disorders0low10
Spasm0low30
Spasm, Ciliary Body0low30
Spasm, Generalized0low30
Spasmophilia0low10
Spasms, Infantile0low10
Spasmus Nutans0low10
Speech Disorders0medium21
Spinal Cord Contusion0low20
Spinal Cord Injuries0low20
Spinal Cord Laceration0low20
Spinal Cord Transection0low20
Spinal Cord Trauma0low20
Spinal Diseases0medium11
Spinal Injuries0low10
Spontaneous Oto-Acoustic Emission Tinnitus0low10
Sprue0low10
Sprue, Celiac0low10
Sprue, Nontropical0low10
Squamous Cell Carcinoma0low60
Squamous Cell Carcinoma of Head and Neck0low10
Squamous Cell Carcinoma of Larynx0low10
Squamous Cell Carcinoma of the Head and Neck0low10
Squamous Cell Carcinoma of the Larynx0low10
Squamous Cell Carcinoma of the Mouth0low10
Squamous Cell Carcinoma of the Nasal Cavity0low10
Squamous Cell Carcinoma, Head And Neck0low10
SREDIu0160NJI u017DIVu010CANI SUSTAV, BOLESTI@hr0low10
St. Vitus's Dance0low80
Stammering0low40
Staphylococcal Infections0low10
Staphylococcus aureus Infection0low10
Static Tremor0medium61
Status Cataplexicus0low10
Status Marmoratus0medium4610
Status Migrainosus0low20
Steatohepatitis0low10
Steatosis of Liver0low10
Stenocardia0low20
Sterility, Male0low10
Stokes-Adams Attacks0low10
Stokes-Adams Syndrome0low10
Stomach Cancer0low20
Stomach Diseases0low10
Stomach Neoplasms0low20
Stomach Ulcer0low20
Streptococcal Infections0low10
Streptozocin Diabetes0low40
Streptozotocin Diabetes0low40
Stress Disorder, Post Traumatic0low10
Stress Disorders, Post-Traumatic0low10
Stress Disorders, Posttraumatic0low10
Stress Headache0low10
Stroke0low10
Stroke, Acute0low10
Stuttering0low40
Stuttering, Acquired0low40
Stuttering, Adult0low40
Stuttering, Childhood0low40
Stuttering, Developmental0low40
Stuttering, Familial Persistent 10low40
Sub-Fertility, Male0low10
Subacute Delirium0low40
Subarachnoid Hemorrhage0low20
Subarachnoid Hemorrhage, Aneurysmal0low20
Subarachnoid Hemorrhage, Intracranial0low20
Subarachnoid Hemorrhage, Spontaneous0low20
Subclinical Seizure0low10
Subcortical Infarction0low10
Subependymal Giant Cell Astrocytoma0low40
Subfertility, Male0low10
Substance Abuse0medium151
Substance Addiction0medium151
Substance Dependence0medium151
Substance Use0medium151
Substance Use Disorders0medium151
Substance Withdrawal Syndrome0medium242
Substance-Induced Psychoses0medium101
Substance-Related Disorders0medium151
Subwakefullness Syndrome0low30
Sudden Death0low20
Suffering, Physical0low50
Superficial Head Injury0low10
Susceptibility, Genetic0low10
Swallowing Disorders0medium21
Sydenham Chorea0low80
Sydenham's Chorea0low80
Sykdommer i sentralnervesystemet@no0low10
Symptom Cluster0low200
Symptomatic Infantile Spasms0low10
Symptomatic Myoclonic Epilepsy0low10
Symptomatic Parkinson Disease0medium202
Symptomatic West Syndrome0low10
Syncopal Episode0low10
Syncopal Vertigo0low10
Syncope0low10
Syncope, Cardiogenic0low10
Syncope, Carotid Sinus0low10
Syncope, Convulsive0low10
Syncope, Deglutitional0low10
Syncope, Effort0low10
Syncope, Hyperventilation0low10
Syncope, Micturition0low10
Syncope, Postural0low10
Syncope, Situational0low10
Syncope, Stokes-Adams0low10
Syncope, Tussive0low10
Syndrome0low200
Syndrome of Inappropriate ADH (SIADH) Secretion0low20
Syndrome X, Insulin Resistance0low10
Syndrome X, Metabolic0low10
Syndrome, Blepharospasm-Oromandibular Dystonia0low20
Systemic Lupus Erythematosus0low20
T Lymphocytic Leukemia0low10
T-Cell Leukemia0low10
T-Cell Lymphoma0low10
T-Lymphocytic Leukemia0low10
T-Lymphotropic Virus Type III Infections, Human0low20
Tachyarrhythmia0low10
Tachycardia0low10
Tactile Allodynia0low20
Tardive Oral Dyskinesia0low10
TBI (Traumatic Brain Injury)0low10
TBIs (Traumatic Brain Injuries)0low10
Teeth Grinding Disorder0low10
Telangiectasia, Cerebello-Oculocutaneous0low10
Temporal Region Trauma0low10
Tension Headache0low10
Tension-Type Headache0low10
Tension-Vascular Headache0low10
Tensor Palatini Induced Tinnitus0low10
Tensor Tympani Induced Tinnitus0low10
Teratoid Tumor0low10
Teratoma0low10
Teratoma, Benign0low10
Teratoma, Cystic0low10
Teratoma, Immature0low10
Teratoma, Malignant0low10
Teratoma, Mature0low10
Testicular Diseases0low10
Tetanilla0low10
Tetanus0low20
Tetany0low10
Tetany, Neonatal0low10
Thalassemia0low10
Thalassemias0low10
Thermal Allodynia0low20
Thesaurismosis0low20
Thoracic Diseases0low10
Throbbing Headache0low30
Thrombocytopenia0low10
Thrombopenia0low10
Thrush0low10
Thymic Cancer0low10
Thymic Neoplasms0low10
Thymic Tumors0low10
Thymoma0low10
Thymus Cancer0low10
Thymus Neoplasms0low10
Thymus Tumors0low10
Thyroid Adenoma0low20
Thyroid Cancer0low20
Thyroid Carcinoma0low20
Thyroid Neoplasms0low20
Thyroid-Associated Ophthalmopathies0low10
Thyroid-Associated Ophthalmopathy0low10
Thyroid-Stimulating Hormone Deficiency0low40
TIA (Transient Ischemic Attack)0low50
Tic0low10
Tic Disorder, Chronic Motor or Vocal0low10
Tic Disorder, Combined Vocal and Multiple Motor0medium72
Tic Disorder, Post-Traumatic0low10
Tic Disorder, Transient0low10
Tic Disorders0low10
Tic Disorders, Childhood0low10
Tic Disorders, Motor0low10
Tic Disorders, Vocal0low10
Tic, Gestural0low10
Tic, Motor0low10
Tic, Transient0low10
Tic, Vocal0low10
Tick-Borne Encephalitis0low10
Tics0low10
Tinnitus0low10
Tinnitus of Vascular Origin0low10
Tinnitus, Clicking0low10
Tinnitus, Leudet0low10
Tinnitus, Leudet's0low10
Tinnitus, Noise Induced0low10
Tinnitus, Objective0low10
Tinnitus, Spontaneous Oto-Acoustic Emission0low10
Tinnitus, Subjective0low10
Tinnitus, Tensor Palatini Induced0low10
Tinnitus, Tensor Tympani Induced0low10
Tissue Pain0low10
Todd Paralysis0low20
Todd's Paralysis0low20
Tonelessness Syndrome0low10
Tongue Diseases0low10
Tonic Clonic Seizure0low90
Tonic Seizure0low90
Tonic Seizures0low90
Tonic-Clonic Seizure0low90
Tonic-Clonic Seizures0low90
Toothache0low10
Torsion Disease of Childhood0medium21
Torsion Dystonia0medium21
Torulosis0low20
Tourette Disease0medium72
Tourette Disorder0medium72
Tourette Syndrome0medium72
Tourette's Disease0medium72
Tourette's Disorder0medium72
Tourette's Syndrome0medium72
Toxic Encephalitis0low10
Toxic Hepatitis0low160
Toxic Psychoses0medium101
Toxicity, Drug0low60
Toxico-Infectious Botulism0low10
Toxoplasma gondii Infection0low10
Toxoplasmosis0low10
Toxoplasmosis, Ocular0low10
Transformation, Neoplastic Cell0low40
Transformation, Viral Cell0low50
Transient Insomnia0low40
Transient Ischemic Attack0low50
Transient Ischemic Attack, Anterior Circulation0low50
Transient Ischemic Attack, Brain Stem0low50
Transient Ischemic Attack, Brainstem0low50
Transient Ischemic Attack, Carotid Circulation0low50
Transient Ischemic Attack, Posterior Circulation0low50
Transient Ischemic Attack, Vertebrobasilar Circulation0low50
Transient Ischemic Attacks, Crescendo0low50
Transient Situational Disturbance0low60
Transient Tic Disorder0low10
Transposition of Great Arteries0low10
Transposition of Great Vessels0low10
Transvestic Fetishism0low10
Transvestism0low10
Trauma0low10
Trauma, Brain0low10
Trauma, Head0low10
Traumatic Brain Injury0low10
Traumatic Encephalopathy0low10
Tremor0medium61
Tremor, Limb0medium61
Tremor, Muscle0medium61
Tremor, Neonatal0medium61
Tremor, Nerve0medium61
Tremor, Perioral0medium61
Tremor, Rubral0low10
Tremor, Semirhythmic0medium61
Triple Negative Breast Cancer0low20
Triple Negative Breast Neoplasms0low20
Triple-Negative Breast Cancer0low20
Triple-Negative Breast Neoplasm0low20
Trismus0low10
Trisomy 130low10
Trisomy 13 Syndrome0low10
Trisomy 13 Syndromes0low10
Tropical Eosinophilia0low10
TSH Deficiency0low40
Tuberculin-Type Hypersensitivity0low20
Tuberculosis, Drug-Resistant0low20
Tuberculosis, MDR0low20
Tuberculosis, Multi-Drug Resistant0low20
Tuberculosis, Multidrug-Resistant0low20
Tuberose Sclerosis0low10
Tuberous Sclerosis0low10
Tuberous Sclerosis Complex0low10
Tumorigenesis0low10
Tumorigenic Transformation0low40
Tumors0low190
Tumors, Breast0medium122
Tumors, Central Nervous System0low10
Type 2 Diabetes0low10
Type 2 Diabetes Mellitus0low10
Type I Hypersensitivity0low10
Type IV Hypersensitivity0low20
u041Du0415u0420u0412u041Du041Eu0419 u0421u0418u0421u0422u0415u041Cu042B u0426u0415u041Du0422u0420u0410u041Bu042Cu041Du041Eu0419 u0411u041Eu041Bu0415u0417u041Du0418@ru0low10
u4E2Du67A2u795Eu7D4Cu7CFBu75BEu60A3@ja0low10
UADT Neoplasm0low10
UADT Neoplasms0low10
Ulcerative Colitis0low10
Uncinate Seizures0low10
Unconscious State0low10
Unconsciousness0low10
Undifferentiated Lymphoma0low10
Unilateral Headache0low30
Unipolar Depression0medium371
Upper Aerodigestive Tract Neoplasm0low10
Upper Aerodigestive Tract Neoplasms0low10
UPS Deficiency0low10
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Urinary Incontinence, Stress0low10
Urinary Stress Incontinence0low10
Urinary Tract Infections0low20
Urogenital Abnormalities0low10
Uroporphyrinogen Synthase Deficiency0low10
Urticaria, Giant0low10
Vascular Accident, Brain0low10
Vascular Diseases, Intracranial0low20
Vascular Hypotension0medium51
Vascular Origin Tinnitus0low10
Vasogenic Brain Edema0low40
Vasogenic Cerebral Edema0low40
Ventricular Pre-Excitation with Arrhythmia0low10
Verbal Fluency Disorders0medium21
Verruca0low10
Vertebrobasilar Circulation Transient Ischemic Attack0low50
Vertebrogenic Pain Syndrome0medium11
Vertex Headache0low30
Vertigo, Aural0low10
Vesication0low10
Viral Cell Transformation0low50
Viral Diseases0low10
Viral Infections0low10
Virilism0low10
Virilization0low10
Virus Diseases0low10
Virus Infections0low10
Visceral Myopathy0low10
Visceral Steatosis0low10
Vision Disability0low20
Vision Disorders0low20
Visual Disorders0low20
Visual Impairment0low20
Vitamin D Deficiency0low30
Vocal Tic Disorders0low10
Voice Disorder, Neurologic0low10
Voice Disorders0low10
Voice Disturbance0low10
Voice Fatigue0low10
Vomiting0low90
Warts0low10
Water Intoxication0low10
Weight Gain0low10
Wernicke Disease0low10
Wernicke Encephalopathy0low10
Wernicke Polioencephalitis, Superior Hemorrhagic0low10
Wernicke Superior Hemorrhagic Polioencephalitis0low10
Wernicke Syndrome0low10
Wernicke-Korsakoff Syndrome0low10
Wernicke's Disease0low10
Wernicke's Encephalopathy0low10
Wernicke's Polioencephalitis, Superior Hemorrhagic0low10
Wernicke's Superior Hemorrhagic Polioencephalitis0low10
Wernicke's Syndrome0low10
West Syndrome0low10
Westphal-Strumpell Syndrome0low10
Wet Lung0low10
Whiplash Injuries0low10
Whooping Cough0low10
Wilson Disease0low10
Wilson Disease, Hepatic Form0low10
Wilson's Disease0low10
Withdrawal Symptoms0medium242
Wolf-Parkinson-White Syndrome0low10
Wolff-Parkinson-White Syndrome0low10
Wound Botulism0low10
Wound Infection0low10
Wounds0low10
Wounds and Injuries0low10
Wounds and Injury0low10
Wounds, Injury0low10
WPW Syndrome0low10
X-Linked Mental Retardation and Macroorchidism0low10
Xeroderma Pigmentosum0low10
XXXY Males0low10
XXY Syndrome0low10
XXY Trisomy0low10
Xxyy Syndrome0low10
Yersinia pestis Infection0low10
Zentralnervensystemkrankheiten@de0low10
Ziekte, centraalzenuwstelsel-@nl0low10
Zika Fever0low20
Zika Virus Disease0low20
Zika Virus Infection0low20
ZikV Infection0low20
Zygomycosis0low10

Research Highlights

Safety/Toxicity (37)

ArticleYear
Novel in vivo potential of trifluoperazine to ameliorate doxorubicin-induced cardiotoxicity involves suppression of NF-κB and apoptosis.
Life sciences, Oct-15, Volume: 283		2021
A randomized, double-blind, comparison of the efficacy and safety of low-dose olanzapine plus low-dose trifluoperazine versus full-dose olanzapine in the acute treatment of schizophrenia.
Schizophrenia research, Volume: 185		2017
Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity.
Neurobiology of aging, Volume: 35, Issue: 7		2014
Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice.
Toxicology and applied pharmacology, Oct-15, Volume: 264, Issue: 2		2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology, Volume: 7, Issue: 12		2011
Developing structure-activity relationships for the prediction of hepatotoxicity.
Chemical research in toxicology, Jul-19, Volume: 23, Issue: 7		2010
Differential involvement of mitochondrial permeability transition in cytotoxicity of 1-methyl-4-phenylpyridinium and 6-hydroxydopamine.
Molecular and cellular biochemistry, Volume: 289, Issue: 1-2		2006
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Current drug discovery technologies, Volume: 1, Issue: 4		2004
Effect of bilirubin on toxicity induced by trifluoperazine, dibucaine and praziquantel to erythrocytes.
Life sciences, Jul-13, Volume: 69, Issue: 8		2001
Effect of the polyamine oxidase inactivator MDL 72527 on N(1)-(n-octanesulfonyl)spermine toxicity.
The international journal of biochemistry & cell biology, Volume: 32, Issue: 10		2000
The effect of trifluoperazine on the genotoxicity of bleomycin in cultured human lymphocytes.
Drug and chemical toxicology, Volume: 23, Issue: 2		2000
The mutagenic and toxic effects of bleomycin and trifluoperazine in Drosophila melanogaster.
Drug and chemical toxicology, Volume: 22, Issue: 2		1999
Cyclosporin A and trifluoperazine, two resistance-modulating agents, increase ivermectin neurotoxicity in mice.
Pharmacology & toxicology, Volume: 84, Issue: 3		1999
Effect of calmodulin-inhibitors and verapamil on the nephrotoxicity of cadmium in rat.
Toxicology letters, Mar-16, Volume: 95, Issue: 1		1998
Effect of nifedipine, verapamil, diltiazem and trifluoperazine on acetaminophen toxicity in mice.
Archives of toxicology, Volume: 70, Issue: 2		1995
Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (adriamycin)-resistant P388 mouse leukemia cells.
Cancer research, Volume: 44, Issue: 11		1984
Natural killer cell cytotoxicity: role of calmodulin.
Biochemical and biophysical research communications, Jun-15, Volume: 121, Issue: 2		1984
Selective cytotoxicity of calmidazolium and trifluoperazine for cycling versus noncycling C3H10T1/2 cells in vitro.
Cancer research, Volume: 46, Issue: 1		1986
Active target cell processes, possibly involving receptor-mediated endocytosis, are critical for expression of cytotoxicity by natural killer cell-derived cytolytic factor.
Cellular immunology, Oct-01, Volume: 102, Issue: 1		1986
Modulation of adriamycin and N-trifluoroacetyladriamycin-14-valerate induced effects on cell cycle traverse and cytotoxicity in P388 mouse leukemia cells by caffeine and the calmodulin inhibitor trifluoperazine.
Cancer research, Volume: 46, Issue: 11		1986
Ca2+-calmodulin regulates the induction and expression of macrophage cytotoxicity.
Journal of biological response modifiers, Volume: 6, Issue: 2		1987
Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular doxorubi
Biochemical pharmacology, Jan-15, Volume: 37, Issue: 2		1988
Modulation in vitro and in vivo of cytotoxicity but not cellular levels of doxorubicin by the calmodulin inhibitor trifluoperazine is dependent on the level of resistance.
British journal of cancer, Volume: 58, Issue: 3		1988
Calmodulin inhibitor trifluoperazine selectively enhances cytotoxic effects of strong vs weak DNA binding antitumor drugs in doxorubicin-resistant P388 mouse leukemia cells.
Biochemical and biophysical research communications, Sep-16, Volume: 131, Issue: 2		1985
In vivo toxicity of phenothiazines to cells of a transplantable tumor.
Cancer chemotherapy and pharmacology, Volume: 16, Issue: 3		1986
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
Molecular pharmacology, Volume: 27, Issue: 3		1985
Chemical modulation of bleomycin induced toxicity.
International journal of radiation oncology, biology, physics, Volume: 12, Issue: 8		1986
Interaction of bleomycin, hyperthermia and a calmodulin inhibitor (trifluoperazine) in mouse tumour cells: I. In vitro cytotoxicity.
British journal of cancer, Volume: 53, Issue: 1		1986
Tamoxifen and trifluoroperazine (Stelazine) potentiate cytostatic/cytotoxic effects of P-30 protein, a novel protein possessing anti-tumor activity.
Cell and tissue kinetics, Volume: 23, Issue: 3		1990
Modulation of doxorubicin-induced chromosomal damage by calmodulin inhibitors and its relationship to cytotoxicity in progressively doxorubicin-resistant tumor cells.
Biochemical pharmacology, Oct-01, Volume: 40, Issue: 7		1990
Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leukemia ce
Biochemical pharmacology, Jun-15, Volume: 41, Issue: 12		1991
Potentiation of cisplatin cytotoxicity in human ovarian carcinoma cell lines by trifluoperazine, a calmodulin inhibitor.
Gynecologic oncology, Volume: 46, Issue: 1		1992
Extra pyramidal side effects associated with paroxetine.
West of England medical journal, Volume: 107, Issue: 3		1992
Toxoplasmosis masquerading as a psychotropic side effect.
The Journal of clinical psychiatry, Volume: 39, Issue: 7		1978
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Acta psychiatrica Scandinavica, Volume: 51, Issue: 2		1975
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (12)

ArticleYear
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Volume: 28, Issue: 3		2003
Effect of chronic trifluoperazine administration and subsequent withdrawal on the production and persistence of perioral behaviours in two rat strains.
Psychopharmacology, Volume: 112, Issue: 4		1993
Evidence for dopamine mediation of submissive gestures in the stumptail macaque monkey.
Pharmacology, biochemistry, and behavior, Volume: 14 Suppl 1		1981
[Various methods of overcoming secondary resistance to treatment developing in relation to adaptation to psychotropic drugs during long-term treatment (clinico-experimental study)].
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), Volume: 84, Issue: 8		1984
Functional increase in striatal dopaminergic activity following continuous long-term treatment with trifluoperazine.
Neuroscience letters, Apr-06, Volume: 45, Issue: 3		1984
Alterations in [Met5]- and [Leu5]enkephalin and neurotensin content in basal ganglia induced by the long-term administration of dopamine agonist and antagonist drugs to rats.
European journal of pharmacology, Nov-04, Volume: 130, Issue: 3		1986
Chronic trifluoperazine treatment does not induce lipid peroxidation in the rat cortex.
Neuroscience letters, May-19, Volume: 76, Issue: 3		1987
Chronic pharmacological manipulation of dopamine receptors in brain.
Neuropharmacology, Volume: 26, Issue: 7B		1987
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
Journal of medicinal chemistry, Volume: 29, Issue: 3		1986
Modulation by adriamycin, daunomycin, verapamil, and trifluoperazine of the biochemical processes linked to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Cancer research, Oct-01, Volume: 49, Issue: 19		1989
The effect of neuroleptics on serum prolactin in schizophrenic patients.
Archives of general psychiatry, Volume: 33, Issue: 3		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (22)

ArticleYear
Photochemical and Pharmacokinetic Characterization of Orally Administered Chemicals to Evaluate Phototoxic Risk.
Journal of pharmaceutical sciences, Volume: 108, Issue: 3		2019
Assessment of Three-Drug Combination Pharmacodynamic Interactions in Pancreatic Cancer Cells.
The AAPS journal, 06-27, Volume: 20, Issue: 5		2018
Regulatory volume decrease in Leishmania mexicana: effect of anti-microtubule drugs.
Memorias do Instituto Oswaldo Cruz, Volume: 108, Issue: 1		2013
Effects of medium calcium, and agents affecting cytoskeletal function, on cellular volume and morphology in liver tissue in vitro.
Journal of cellular biochemistry, Volume: 113, Issue: 6		2012
Calcium and cytoskeleton signaling during cell volume regulation in isolated nematocytes of Aiptasia mutabilis (Cnidaria: Anthozoa).
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Volume: 147, Issue: 1		2007
Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells.
Journal of cellular physiology, Volume: 189, Issue: 3		2001
Amino acid efflux and cell volume regulation in cerebrocortical minislices prepared from chronically hyponatraemic and hypernatraemic rats.
Neurochemistry international, Volume: 35, Issue: 6		1999
Volume-dependent taurine release from cultured astrocytes requires permissive [Ca(2+)](i) and calmodulin.
The American journal of physiology, Volume: 277, Issue: 4		1999
Taurine efflux and the regulation of cell volume in incubated slices of rat cerebral cortex.
Biochimica et biophysica acta, Mar-10, Volume: 1221, Issue: 1		1994
Potassium and taurine release are highly correlated with regulatory volume decrease in neonatal primary rat astrocyte cultures.
Journal of neurochemistry, Volume: 63, Issue: 3		1994
The Na(+)-independent taurine influx in flounder erythrocytes and its association with the volume regulatory taurine efflux.
The Journal of experimental biology, Volume: 186		1994
Induction of 86Rb fluxes by Ca2+ and volume changes in thymocytes and their isolated membranes.
Journal of cellular physiology, Volume: 116, Issue: 3		1983
Volume-induced anion conductance in human B lymphocytes is cation independent.
The American journal of physiology, Volume: 245, Issue: 1		1983
Na+,Cl- cotransport in Ehrlich ascites tumor cells activated during volume regulation (regulatory volume increase).
The Journal of membrane biology, Volume: 76, Issue: 3		1983
Involvement of calcium and cytoskeleton in gallbladder epithelial cell volume regulation.
The American journal of physiology, Volume: 248, Issue: 1 Pt 1		1985
A pharmacokinetic study of trifluoperazine in two ethnic populations.
Psychopharmacology, Volume: 95, Issue: 3		1988
Osmotic and phorbol ester-induced activation of Na+/H+ exchange: possible role of protein phosphorylation in lymphocyte volume regulation.
The Journal of cell biology, Volume: 101, Issue: 1		1985
Evidence of calmodulin involvement in cell volume recovery following hypo-osmotic stress.
Cell calcium, Volume: 10, Issue: 3		1989
Involvement of cell calcium and transmembrane potential in control of hepatocyte volume.
Hepatology (Baltimore, Md.), Volume: 13, Issue: 5		1991
Efflux and accumulation of amino nitrogen in relation to the volume of rat renal inner medullary cells exposed to media of variable osmolality.
Biochimica et biophysica acta, Feb-03, Volume: 1133, Issue: 3		1992
Volume regulation in rat pheochromocytoma cultured cells submitted to hypoosmotic conditions.
Archives internationales de physiologie, de biochimie et de biophysique, Volume: 99, Issue: 1		1991
Regulatory volume decrease by cultured non-pigmented ciliary epithelial cells.
Experimental eye research, Volume: 54, Issue: 2		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (9)

ArticleYear
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
Cell death & disease, 09-26, Volume: 9, Issue: 10		2018
Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs.
Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue: 29		2007
Radioimmunoassay for trifluoperazine in human plasma.
British journal of clinical pharmacology, Volume: 12, Issue: 2		1981
A gas chromatographic mass spectrometric assay for plasma trifluoperazine concentrations following single doses.
Biomedical mass spectrometry, Volume: 9, Issue: 5		1982
Relative bioavailability of a commercial trifluoperazine tablet formulation using a radioimmunoassay technique.
Journal of pharmaceutical sciences, Volume: 73, Issue: 2		1984
Effects of phenothiazines and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide on rat colonic absorption of cefmetazole.
Journal of pharmacobio-dynamics, Volume: 9, Issue: 5		1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (48)

ArticleYear
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
Turk psikiyatri dergisi = Turkish journal of psychiatry,Summer, Volume: 33, Issue: 2		2022
Photochemical and Pharmacokinetic Characterization of Orally Administered Chemicals to Evaluate Phototoxic Risk.
Journal of pharmaceutical sciences, Volume: 108, Issue: 3		2019
A randomized, double-blind, comparison of the efficacy and safety of low-dose olanzapine plus low-dose trifluoperazine versus full-dose olanzapine in the acute treatment of schizophrenia.
Schizophrenia research, Volume: 185		2017
Repurposing ospemifene for potentiating an antigen-specific immune response.
Menopause (New York, N.Y.), Volume: 24, Issue: 4		2017
Salvia miltiorrhiza causes tonic contraction in rat ileum through Ca²⁺-calmodulin pathway.
Journal of ethnopharmacology, Aug-01, Volume: 142, Issue: 3		2012
Risperidone and olanzapine versus another first generation antipsychotic in patients with schizophrenia inadequately responsive to first generation antipsychotics.
Pharmacopsychiatry, Volume: 45, Issue: 2		2012
FDA-approved drug labeling for the study of drug-induced liver injury.
Drug discovery today, Volume: 16, Issue: 15-16		2011
Spectrophotometric determination of isopropamide iodide and trifluoperazine hydrochloride in presence of trifluoperazine oxidative degradate.
Drug testing and analysis, Volume: 2, Issue: 4		2010
[Prescription of traditional neuroleptics in the remission period for schizophrenic patients with excess of body mass caused by atypical antipsychotics].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, Volume: 107, Issue: 2		2007
THE EFFECT OF PHENOTHIAZINES ON THE ELECTROCARDIOGRAM.
Canadian Medical Association journal, Sep-05, Volume: 91		1964
Effects of trifluoperazine on the contraction kinetics of the isolated intact tracheal and pulmonary artery smooth muscle.
The Thoracic and cardiovascular surgeon, Volume: 50, Issue: 1		2002
Cellular signalling of PCH-induced pigment aggregation in the crustacean Macrobrachium potiuna erythrophores.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Volume: 167, Issue: 8		1997
A systematic review and critical comparison of internal standards for the routine liquid chromatographic assay of amiodarone and desethylamiodarone.
Therapeutic drug monitoring, Volume: 18, Issue: 2		1996
Protection in the late stages of paracetamol-induced liver cell injury with fructose, cyslosporin A and trifluoperazine.
Toxicology, Mar-18, Volume: 107, Issue: 3		1996
Divalent cation channels activated by phenothiazines in membrane of rat ventricular myocytes.
The Journal of membrane biology, Volume: 147, Issue: 2		1995
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
The Journal of pharmacology and experimental therapeutics, Volume: 265, Issue: 1		1993
Overdosage of misoprostol in pregnancy.
American journal of obstetrics and gynecology, Volume: 171, Issue: 2		1994
Study of the activation mechanism of adriamycin on rat mast cells.
Agents and actions, Volume: 42, Issue: 3-4		1994
Inhibition by trifluoperazine of glycogenolytic effects of phenylephrine, vasopressin, and angiotensin II.
Endocrinologia japonica, Volume: 29, Issue: 3		1982
Inhibition by calmodulin antagonists of glioblast DNA synthesis and morphological changes induced by glia maturation factor.
Brain research, Volume: 255, Issue: 4		1982
[Various methods of overcoming secondary resistance to treatment developing in relation to adaptation to psychotropic drugs during long-term treatment (clinico-experimental study)].
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), Volume: 84, Issue: 8		1984
Proteoglycan production by bovine granulosa cells in vitro occurs in response to fsh.
Molecular and cellular endocrinology, Volume: 29, Issue: 1		1983
Phenothiazines cause a shift in the cAMP dose-response: selection of resistant variants in a murine thymoma line.
Journal of cellular physiology, Volume: 119, Issue: 1		1984
Trifluoperazine antagonizes postsynaptic alpha 1-but not alpha 2-adrenoceptor-mediated pressor responses in the rat.
European journal of pharmacology, Oct-15, Volume: 105, Issue: 3-4		1984
Membrane effects of phenothiazines in yeasts. I. Stimulation of calcium and potassium fluxes.
Biochimica et biophysica acta, Sep-07, Volume: 733, Issue: 2		1983
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
Pharmacology, biochemistry, and behavior, Volume: 12, Issue: 1		1980
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
British journal of pharmacology, Volume: 34, Issue: 2		1968
Persistent phenothiazine dyskinesia treated with tetrabenazine.
British medical journal, Oct-02, Volume: 4, Issue: 5778		1971
Joint cholinergic-serotonergic control of neocortical and hippocampal electrical activity in relation to behavior: effects of scopolamine, ditran, trifluoperazine and amphetamine.
Physiology & behavior, Volume: 38, Issue: 1		1986
Cytogenetic effects of trifluoperazine in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Volume: 25, Issue: 8		1987
Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C.
Diabetes, Volume: 37, Issue: 11		1988
Calmodulin-independent inhibition of platelet phospholipase A2 by calmodulin antagonists.
Archives of biochemistry and biophysics, May-01, Volume: 246, Issue: 2		1986
Behavioral interaction of adenosine and trifluoperazine in mice.
Neuroscience letters, Jan-07, Volume: 53, Issue: 1		1985
[Studies on the gap junctional intercellular communication (GJIC) of human stomach carcinoma cells in comparison with normal cells and the effect of the tumor promoter, TPA].
Shi yan sheng wu xue bao, Volume: 22, Issue: 2		1989
Use of neuroleptics after an episode of neuroleptic malignant syndrome.
Canadian journal of psychiatry. Revue canadienne de psychiatrie, Volume: 34, Issue: 4		1989
In vivo characterization of combination antitumor chemotherapy with calcium channel blockers and cis-diamminedichloroplatinum(II).
Cancer research, Jun-01, Volume: 49, Issue: 11		1989
Induced interphase cell retraction: its reversal and EGF potentiation.
Tissue & cell, Volume: 21, Issue: 3		1989
Inhibitory effects of calcium channel agonists on renin release from rat kidney cortical slices.
The Journal of pharmacology and experimental therapeutics, Volume: 241, Issue: 3		1987
Involvement of cell calcium and transmembrane potential in control of hepatocyte volume.
Hepatology (Baltimore, Md.), Volume: 13, Issue: 5		1991
Extra pyramidal side effects associated with paroxetine.
West of England medical journal, Volume: 107, Issue: 3		1992
[Effect of pharmacologic substances on the dominance-submission relationship in a pair of rats].
Biulleten' eksperimental'noi biologii i meditsiny, Volume: 86, Issue: 9		1978
A double-blind comparison of loxitane--loxapine succinate and trifluoperazine hydrochloride in chronic schizophrenic patients.
Diseases of the nervous system, Volume: 36, Issue: 6		1975
Efficacy of loxapine in the treatment of paranoid schizophrenia.
Psychopharmacology, Jan-31, Volume: 51, Issue: 2		1977
High-dosage and versatile drug therapy with treatment-resistant psychotic patients.
Hospital & community psychiatry, Volume: 27, Issue: 1		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (6)

ArticleYear
Characterizing the interactions of the antipsychotic drug trifluoperazine with bovine serum albumin: Probing the drug-protein and drug-drug interactions using multi-spectroscopic approaches.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Feb-05, Volume: 226		2020
Assessment of Three-Drug Combination Pharmacodynamic Interactions in Pancreatic Cancer Cells.
The AAPS journal, 06-27, Volume: 20, Issue: 5		2018
Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction.
Pharmacological research, Volume: 110		2016
Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
British journal of cancer, Volume: 67, Issue: 6		1993
In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii.
Antimicrobial agents and chemotherapy, Volume: 38, Issue: 6		1994
Drug interaction with cardiac and skeletal muscle troponin C.
Biomedical science, Volume: 1, Issue: 1		1990
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]