g(m3) ganglioside

Description

G(M3) Ganglioside: A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis. [MeSH]

alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:1(15Z)) : A sialotriaosylceramide consisting of beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide(d18:1/24:1(15Z)). [CHeBI]

Cross-References

ID Source	ID
PubMed CID	86583360
CHEBI ID	84989
CHEBI ID	84118
MeSH ID	M0008926

Synonyms (12)

Synonym
monosialoganglioside gm3
monosialodihexosylganglioside
g(m3) ganglioside
CHEBI:84989
alpha-neu5ac-(2->3)-beta-d-gal-(1->4)-beta-d-glc-(1<->1')-cer(d18:1/24:1(15z))
gm3-d18:1/24:1(15z)
(2s,3r,4e)-3-hydroxy-2-[(15z)-tetracos-15-enoylamino]octadec-4-en-1-yl (6r)-5-(acetylamino)-3,5-dideoxy-6-[(1r,2r)-1,2,3-trihydroxypropyl]-beta-lthreo--hex-2-ulopyranonosyl-(2->3)-beta-d-galactopyranosyl-(1->4)-beta-d-glucopyranoside
alpha-neu5ac-(2->3)-beta-d-gal-(1->4)-beta-d-glc-(1<->1)-n-cis-tetracos-15-enoylsphingosine
(2s,3r,4e)-3-hydroxy-2-[(15z)-tetracos-15-enoylamino]octadec-4-en-1-yl 5-acetamido-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranonosyl-(2->3)-beta-d-galactopyranosyl-(1->4)-beta-d-glucopyranoside
nana-gal-glc-ceramide
CHEBI:84118
alpha-neu5ac-(2->3)-beta-d-gal-(1->4)-beta-d-glc-(1<->1)-n-(15z)-tetracos-15-enoylsphingosine

Roles (1)

Role	Description
mouse metabolite	Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).

Drug Classes (3)

Class	Description
sialotriaosylceramide	A ganglioside in which the oligosaccharide portion is composed of a trisaccharide, to which one or more sialic acid residues are attached.
sialodiosylceramide	A ganglioside in which the number of residues in the oligosaccharide chain is two.
alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide	A sialodiosylceramide consisting of the trisaccharide alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide.

Research

Studies (982)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	194 (19.76)	18.7374
1990's	282 (28.72)	18.2507
2000's	261 (26.58)	29.6817
2010's	199 (20.26)	24.3611
2020's	46 (4.68)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	17 (1.68%)	5.53%
Reviews	48 (4.75%)	6.00%
Case Studies	13 (1.29%)	4.05%
Observational	1 (0.10%)	0.25%
Other	931 (92.18%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
g(m2) ganglioside	93	N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine; sialotriaosylceramide	antigen	1976	2023	26.0	medium	0	24	31	23	14	1
n-glycolylneuraminyllactosylceramide	0	sialotriaosylceramide	tumour antigen	0	0		low	0	0	0	0	0	0

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
alpha-hydroxyglutarate	0	2-hydroxydicarboxylic acid; dicarboxylic fatty acid	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
alpha-ketoadipic acid	0	oxo dicarboxylic acid	human urinary metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3-hydroxyanthranilic acid	0	aminobenzoic acid; monohydroxybenzoic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3-mercaptopyruvic acid	0	2-oxo monocarboxylic acid; thiol	antidote to cyanide poisoning; Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-carbamoyl-beta-alanine	0	beta-alanine derivative	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
4-aminobutyraldehyde	0	aminobutanal; omega-aminoaldehyde	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
4-hydroxybenzaldehyde	0	hydroxybenzaldehyde	EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
4-hydroxyphenylacetic acid	0	monocarboxylic acid; phenols	fungal metabolite; human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
isocaproaldehyde	0	alpha-CH2-containing aldehyde	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
aminolevulinic acid	0	4-oxo monocarboxylic acid; amino acid zwitterion; delta-amino acid	antineoplastic agent; dermatologic drug; Escherichia coli metabolite; human metabolite; mouse metabolite; photosensitizing agent; plant metabolite; prodrug; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
ethylene glycol	0	ethanediol; glycol	metabolite; mouse metabolite; solvent; toxin	0	0		low	0	0	0	0	0	0
acetaldehyde	0	aldehyde	carcinogenic agent; EC 3.5.1.4 (amidase) inhibitor; electron acceptor; Escherichia coli metabolite; human metabolite; mouse metabolite; mutagen; oxidising agent; Saccharomyces cerevisiae metabolite; teratogenic agent	0	0		low	0	0	0	0	0	0
acetyl phosphate	0	acyl monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
adenine	0	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
agmatine	0	guanidines; primary amino compound	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
allantoic acid	0	ureas	mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
aminoacetone	0	methyl ketone; propanones	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
ammonium hydroxide	0	azane; gas molecular entity; mononuclear parent hydride	EC 3.5.1.4 (amidase) inhibitor; metabolite; mouse metabolite; neurotoxin; NMR chemical shift reference compound; nucleophilic reagent; refrigerant	0	0		low	0	0	0	0	0	0
anthranilic acid	0	aminobenzoic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
betaine aldehyde	0	quaternary ammonium ion	Aspergillus metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
hydrobromic acid	0	gas molecular entity; hydrogen halide; mononuclear parent hydride	mouse metabolite	0	0		low	0	0	0	0	0	0
butyraldehyde	0	butanals	biomarker; Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-butanol	0	alkyl alcohol; primary alcohol; short-chain primary fatty alcohol	human metabolite; mouse metabolite; protic solvent	0	0		low	0	0	0	0	0	0
cadaverine	0	alkane-alpha,omega-diamine	Daphnia magna metabolite; Escherichia coli metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
carbamyl phosphate	0	acyl monophosphate; one-carbon compound	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
carbon monoxide	0	carbon oxide; gas molecular entity; one-carbon compound	biomarker; EC 1.9.3.1 (cytochrome c oxidase) inhibitor; human metabolite; ligand; metabolite; mitochondrial respiratory-chain inhibitor; mouse metabolite; neurotoxin; neurotransmitter; P450 inhibitor; probe; signalling molecule; vasodilator agent	0	0		low	0	0	0	0	0	0
carnitine	0	amino-acid betaine	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
choline	0	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
hydrochloric acid	0	chlorine molecular entity; gas molecular entity; hydrogen halide; mononuclear parent hydride	mouse metabolite	0	0		low	0	0	0	0	0	0
coproporphyrinogen iii	0	coproporphyrinogen	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
aminoethylphosphonic acid	0	phosphonic acids; primary amino compound; zwitterion	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,2-dihydroxy-1,2-dihydronaphthalene	0	dihydronaphthalenes; naphthalenediols	bacterial xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
4-nitrophenylphosphate	0	aryl phosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
trimethylenediamine	0	alkane-alpha,omega-diamine	human metabolite; mouse metabolite; reagent	0	0		low	0	0	0	0	0	0
n(1)-methylnicotinamide	0	pyridinium ion	algal metabolite; anti-inflammatory agent; human urinary metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
phosphonoacetaldehyde	0	phosphonic acids	mouse metabolite	0	0		low	0	0	0	0	0	0
gamma-guanidinobutyric acid	0	guanidines; monocarboxylic acid; zwitterion	fungal metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
phosphoglycolate	0	carboxyalkyl phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hydrogen selenide	0	mononuclear parent hydride; selenium hydride	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
alpha-keto-delta-guanidinovaleric acid	0	2-oxo monocarboxylic acid; zwitterion	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
creatine	0	glycine derivative; guanidines; zwitterion	geroprotector; human metabolite; mouse metabolite; neuroprotective agent; nutraceutical	0	0		low	0	0	0	0	0	0
cytosine	0	aminopyrimidine; pyrimidine nucleobase; pyrimidone	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
3,3-dimethylallyl pyrophosphate	0	prenol phosphate	epitope; Escherichia coli metabolite; mouse metabolite; phosphoantigen	0	0		low	0	0	0	0	0	0
dihydrouracil	0	pyrimidone	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
diethyl phosphate	0	dialkyl phosphate	human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
o,o-diethyl phosphorothionate	0	organic thiophosphate	human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dihydrolipoamide	0	dithiol; monocarboxylic acid amide	cofactor; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
dihydroxyacetone phosphate	0	glycerone phosphates; primary alpha-hydroxy ketone	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
dihydroxyacetone	0	ketotriose; primary alpha-hydroxy ketone	antifungal agent; Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
dimethylglycine	0	amino acid zwitterion; N-methyl-amino acid; N-methylglycines	Daphnia magna metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
ethanolamine	0	ethanolamines; primary alcohol; primary amine	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
formaldehyde	0	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
glycerol	1	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent	2005	2005	19.0	low	0	0	0	1	0	0
glyoxylic acid	0	2-oxo monocarboxylic acid; aldehydic acid	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
glycocyamine	0	guanidinoacetic acids; zwitterion	bacterial metabolite; human metabolite; mouse metabolite; nutraceutical; rat metabolite	0	0		low	0	0	0	0	0	0
carbonic acid	0	carbon oxoacid; chalcocarbonic acid	mouse metabolite	0	0		low	0	0	0	0	0	0
hydrogen carbonate	0	carbon oxoanion	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
histamine	0	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter	0	0		low	0	0	0	0	0	0
hydantoin-5-propionic acid	0	imidazolidine-2,4-dione; monocarboxylic acid	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hydroquinone	0	benzenediol; hydroquinones	antioxidant; carcinogenic agent; cofactor; Escherichia coli metabolite; human xenobiotic metabolite; mouse metabolite; skin lightening agent	0	0		low	0	0	0	0	0	0
hydroxymethylbilane	0	bilanes	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
indole-3-acetaldehyde	0	indoleacetaldehyde	bacterial metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
indoleacetic acid	0	indole-3-acetic acids; monocarboxylic acid	auxin; human metabolite; mouse metabolite; plant hormone; plant metabolite	0	0		low	0	0	0	0	0	0
lactaldehyde	0	hydroxyaldehyde; propanals	mouse metabolite	0	0		low	0	0	0	0	0	0
lipoamide	0	dithiolanes; monocarboxylic acid amide	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyruvaldehyde	1	2-oxo aldehyde; propanals	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	2021	2021	3.0	low	0	0	0	0	0	1
methanol	2	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	1999	2009	20.0	low	0	0	1	1	0	0
melatonin	0	acetamides; tryptamines	anticonvulsant; central nervous system depressant; geroprotector; hormone; human metabolite; immunological adjuvant; mouse metabolite; radical scavenger	0	0		low	0	0	0	0	0	0
n-acetylserotonin	0	acetamides; N-acylserotonin; phenols	antioxidant; human metabolite; mouse metabolite; tropomyosin-related kinase B receptor agonist	0	0		low	0	0	0	0	0	0
naphthalene	0	naphthalenes; ortho-fused bicyclic arene	apoptosis inhibitor; carcinogenic agent; environmental contaminant; mouse metabolite; plant metabolite; volatile oil component	0	0		low	0	0	0	0	0	0
niacinamide	0	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor	0	0		low	0	0	0	0	0	0
niacin	0	pyridine alkaloid; pyridinemonocarboxylic acid; vitamin B3	antidote; antilipemic drug; EC 3.5.1.19 (nicotinamidase) inhibitor; Escherichia coli metabolite; human urinary metabolite; metabolite; mouse metabolite; plant metabolite; vasodilator agent	0	0		low	0	0	0	0	0	0
hydroxide ion	0	oxygen hydride	mouse metabolite	0	0		low	0	0	0	0	0	0
orotic acid	0	pyrimidinemonocarboxylic acid	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
4-nitrophenol	0	4-nitrophenols	human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hexadecanal	0	2,3-saturated fatty aldehyde; long-chain fatty aldehyde	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
parathion	0	C-nitro compound; organic thiophosphate; organothiophosphate insecticide	acaricide; agrochemical; avicide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; mouse metabolite	0	0		low	0	0	0	0	0	0
phenanthrene	0	ortho-fused polycyclic arene; ortho-fused tricyclic hydrocarbon; phenanthrenes	environmental contaminant; mouse metabolite	0	0		low	0	0	0	0	0	0
phenol	0	phenols	antiseptic drug; disinfectant; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phenylacetaldehyde	0	alpha-CH2-containing aldehyde; phenylacetaldehydes	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
phenethylamine	0	alkaloid; aralkylamine; phenylethylamine	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phosphorylcholine	0	phosphocholines	allergen; epitope; hapten; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phosphorylethanolamine	0	phosphoethanolamine; primary amino compound	algal metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
porphobilinogen	0	aralkylamino compound; dicarboxylic acid; pyrroles	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
propylene glycol	0	glycol; propane-1,2-diols	allergen; human xenobiotic metabolite; mouse metabolite; protic solvent	0	0		low	0	0	0	0	0	0
pyridoxal	0	hydroxymethylpyridine; methylpyridines; monohydroxypyridine; pyridinecarbaldehyde; vitamin B6	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyridoxal phosphate	0	methylpyridines; monohydroxypyridine; pyridinecarbaldehyde; vitamin B6 phosphate	coenzyme; cofactor; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyridoxamine	0	aminoalkylpyridine; hydroxymethylpyridine; monohydroxypyridine; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyridoxamine phosphate	0	aminoalkylpyridine; methylpyridines; monohydroxypyridine; vitamin B6 phosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyridoxine	0	hydroxymethylpyridine; methylpyridines; monohydroxypyridine; vitamin B6	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
pyridoxine 5-phosphate	0	vitamin B6 phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
quinolinic acid	1	pyridinedicarboxylic acid	Escherichia coli metabolite; human metabolite; mouse metabolite; NMDA receptor agonist	2014	2014	10.0	low	0	0	0	0	1	0
sarcosine	0	N-alkylglycine zwitterion; N-alkylglycine; N-methyl-amino acid; N-methylglycines	Escherichia coli metabolite; glycine receptor agonist; glycine transporter 1 inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
succinic semialdehyde	0	aldehydic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
tartronate semialdehyde	0	2-hydroxy monocarboxylic acid; 3-oxo monocarboxylic acid; aldehyde	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
taurine	0	amino sulfonic acid; zwitterion	antioxidant; Escherichia coli metabolite; glycine receptor agonist; human metabolite; mouse metabolite; nutrient; radical scavenger; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
thiamine	0	primary alcohol; vitamin B1	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
thymine	0	pyrimidine nucleobase; pyrimidone	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
tryptamine	0	aminoalkylindole; aralkylamino compound; indole alkaloid; tryptamines	human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
uracil	0	pyrimidine nucleobase; pyrimidone	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
uric acid	0	uric acid	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
urea	0	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
uroporphyrinogen iii	0	uroporphyrinogen	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
isopentenyl pyrophosphate	0	prenol phosphate	antigen; antioxidant; epitope; Escherichia coli metabolite; mouse metabolite; phosphoantigen	0	0		low	0	0	0	0	0	0
perillic acid	0	alpha,beta-unsaturated monocarboxylic acid; cyclohexenecarboxylic acid	antineoplastic agent; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
homovanillic acid	0	guaiacols; monocarboxylic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hydroxyindoleacetic acid	0	indole-3-acetic acids	drug metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-methoxytryptamine	0	aromatic ether; primary amino compound; tryptamines	5-hydroxytryptamine 2A receptor agonist; 5-hydroxytryptamine 2B receptor agonist; 5-hydroxytryptamine 2C receptor agonist; antioxidant; cardioprotective agent; human metabolite; mouse metabolite; neuroprotective agent; radiation protective agent; serotonergic agonist	0	0		low	0	0	0	0	0	0
6-hydroxymelatonin	0	acetamides; tryptamines	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
adrenic acid	0	docosatetraenoic acid	mouse metabolite	0	0		low	0	0	0	0	0	0
benzo(a)pyrene	0	ortho- and peri-fused polycyclic arene	carcinogenic agent; mouse metabolite	0	0		low	0	0	0	0	0	0
caffeine	0	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic	0	0		low	0	0	0	0	0	0
chloral hydrate	0	aldehyde hydrate; ethanediol; organochlorine compound	general anaesthetic; mouse metabolite; sedative; xenobiotic	0	0		low	0	0	0	0	0	0
2,5-dihydroxybenzoic acid	0	dihydroxybenzoic acid	EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; fungal metabolite; human metabolite; MALDI matrix material; mouse metabolite	0	0		low	0	0	0	0	0	0
tele-methylhistamine	0	imidazoles; primary amino compound	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
quinone	0	1,4-benzoquinones	cofactor; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,7-dimethylxanthine	0	dimethylxanthine	central nervous system stimulant; human blood serum metabolite; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
theobromine	0	dimethylxanthine	adenosine receptor antagonist; bronchodilator agent; food component; human blood serum metabolite; mouse metabolite; plant metabolite; vasodilator agent	0	0		low	0	0	0	0	0	0
tyramine	0	monoamine molecular messenger; primary amino compound; tyramines	EC 3.1.1.8 (cholinesterase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter	0	0		low	0	0	0	0	0	0
corticosterone	0	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
estriol	0	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid	estrogen; human metabolite; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
sorbitol	0	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent	0	0		low	0	0	0	0	0	0
thymidine	5	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite	1984	1997	31.4	low	0	1	4	0	0	0
hydroxyproline	0	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
thyroxine	0	2-halophenol; iodophenol; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; thyroxine zwitterion; thyroxine	antithyroid drug; human metabolite; mouse metabolite; thyroid hormone	0	0		low	0	0	0	0	0	0
aldosterone	0	11beta-hydroxy steroid; 18-oxo steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid hormone; mineralocorticoid; primary alpha-hydroxy ketone; steroid aldehyde	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
estrone	0	17-oxo steroid; 3-hydroxy steroid; phenolic steroid; phenols	antineoplastic agent; bone density conservation agent; estrogen; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
androsterone	0	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid; C19-steroid	androgen; anticonvulsant; human blood serum metabolite; human metabolite; human urinary metabolite; mouse metabolite; pheromone	0	0		low	0	0	0	0	0	0
etiocholanolone	0	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dehydroepiandrosterone	0	17-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; androstanoid	androgen; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
triiodothyronine	0	2-halophenol; amino acid zwitterion; iodophenol; iodothyronine	human metabolite; mouse metabolite; thyroid hormone	0	0		low	0	0	0	0	0	0
serine	6	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	1978	2006	29.7	low	0	2	2	2	0	0
aspartic acid	1	aspartate family amino acid; aspartic acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; mouse metabolite; neurotransmitter	2004	2004	20.0	low	0	0	0	1	0	0
glutamine	0	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
lysine	2	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	1994	2007	23.5	low	0	0	1	1	0	0
sucrose	0	glycosyl glycoside	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; sweetening agent	0	0		low	0	0	0	0	0	0
uridine monophosphate	0	pyrimidine ribonucleoside 5'-monophosphate; uridine 5'-phosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
uridine diphosphate	0	pyrimidine ribonucleoside 5'-diphosphate; uridine 5'-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
galactose	19	D-galactose; galactopyranose	Escherichia coli metabolite; mouse metabolite	1964	2008	33.2	low	0	6	11	2	0	0
levodopa	0	amino acid zwitterion; dopa; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	allelochemical; antidyskinesia agent; antiparkinson drug; dopaminergic agent; hapten; human metabolite; mouse metabolite; neurotoxin; plant growth retardant; plant metabolite; prodrug	0	0		low	0	0	0	0	0	0
cysteamine	0	amine; thiol	geroprotector; human metabolite; mouse metabolite; radiation protective agent	0	0		low	0	0	0	0	0	0
leucine	0	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
androstenedione	0	17-oxo steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cytidine monophosphate	0	cytidine 5'-phosphate; pyrimidine ribonucleoside 5'-monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cytidine diphosphate	0	cytidine 5'-phosphate; pyrimidine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
uridine triphosphate	0	pyrimidine ribonucleoside 5'-triphosphate; uridine 5'-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
methionine	1	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical	1992	1992	32.0	low	0	0	1	0	0	0
phenylalanine	0	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
desoxycorticosterone	0	20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; mineralocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cytidine	0	cytidines	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
cytidine triphosphate	0	cytidine 5'-phosphate; pyrimidine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-naphthaldehyde	0	naphthaldehyde	mouse metabolite	0	0		low	0	0	0	0	0	0
2-naphthaldehyde	0	naphthaldehyde	mouse metabolite	0	0		low	0	0	0	0	0	0
17-alpha-hydroxyprogesterone	0	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; tertiary alpha-hydroxy ketone	human metabolite; metabolite; mouse metabolite; progestin	0	0		low	0	0	0	0	0	0
ornithine	0	non-proteinogenic L-alpha-amino acid; ornithine	algal metabolite; hepatoprotective agent; mouse metabolite	0	0		low	0	0	0	0	0	0
asparagine	0	amino acid zwitterion; asparagine; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
histidine	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	2014	2014	10.0	low	0	0	0	0	1	0
valine	0	L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid; valine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
threonine	0	amino acid zwitterion; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid; threonine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
tryptophan	1	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	1999	1999	25.0	low	0	0	1	0	0	0
isoleucine	0	aspartate family amino acid; isoleucine; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
arginine	0	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical	0	0		low	0	0	0	0	0	0
methylamine	0	methylamines; one-carbon compound; primary aliphatic amine	mouse metabolite	0	0		low	0	0	0	0	0	0
ethylene oxide	0	gas molecular entity; oxacycle; saturated organic heteromonocyclic parent	allergen; mouse metabolite; mutagen	0	0		low	0	0	0	0	0	0
vinylidene chloride	0	chloroethenes	carcinogenic agent; mouse metabolite; mutagen	0	0		low	0	0	0	0	0	0
trichloroacetaldehyde	0	aldehyde; organochlorine compound	mouse metabolite	0	0		low	0	0	0	0	0	0
trichloroacetic acid	1	monocarboxylic acid; organochlorine compound	carcinogenic agent; metabolite; mouse metabolite	2009	2009	15.0	low	0	0	0	1	0	0
gibberellic acid	0	C19-gibberellin; gibberellin monocarboxylic acid; lactone; organic heteropentacyclic compound	mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
trichloroethylene	0	chloroethenes	inhalation anaesthetic; mouse metabolite	0	0		low	0	0	0	0	0	0
pyridoxic acid	0	hydroxymethylpyridine; methylpyridines; monohydroxypyridine; vitamin B6	human urinary metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-nitronaphthalene	0	mononitronaphthalene	environmental contaminant; mouse metabolite	0	0		low	0	0	0	0	0	0
beta-glucono-1,5-lactone	0	aldono-1,5-lactone; gluconolactone	animal metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-naphthoic acid	0	naphthoic acid	mouse metabolite; xenobiotic metabolite	0	0		low	0	0	0	0	0	0
phosphoribosyl pyrophosphate	0	5-O-phosphono-D-ribofuranosyl diphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
methylphenyl carbinol	0	aromatic alcohol	mouse metabolite	0	0		low	0	0	0	0	0	0
trehalose	0	trehalose	Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
4-hydroxyacetophenone	0	monohydroxyacetophenone	fungal metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
styrene	0	styrenes; vinylarene; volatile organic compound	mouse metabolite; mutagen; plant metabolite	0	0		low	0	0	0	0	0	0
2-phenylacetamide	0	monocarboxylic acid amide	mouse metabolite	0	0		low	0	0	0	0	0	0
4-bromophenol	0	bromophenol	human urinary metabolite; human xenobiotic metabolite; marine metabolite; mouse metabolite; persistent organic pollutant; rat metabolite	0	0		low	0	0	0	0	0	0
ethylene dibromide	0	bromoalkane; bromohydrocarbon	algal metabolite; carcinogenic agent; fumigant; marine metabolite; mouse metabolite; mutagen	0	0		low	0	0	0	0	0	0
bromobenzene	0	bromoarene; bromobenzenes; volatile organic compound	hepatotoxic agent; mouse metabolite; non-polar solvent	0	0		low	0	0	0	0	0	0
2-heptanone	0	dialkyl ketone; methyl ketone	mouse metabolite; pheromone	0	0		low	0	0	0	0	0	0
2,2,2-trichloroethanol	0	chloroethanol	mouse metabolite	0	0		low	0	0	0	0	0	0
acetol	0	methyl ketone; primary alcohol; primary alpha-hydroxy ketone; propanones	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-naphthol	0	naphthol	antinematodal drug; genotoxin; human urinary metabolite; human xenobiotic metabolite; mouse metabolite; radical scavenger	0	0		low	0	0	0	0	0	0
pregnenolone	0	20-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; C21-steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
20-alpha-dihydroprogesterone	0	20-hydroxypregn-4-en-3-one	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
D-proline	0	D-alpha-amino acid zwitterion; D-alpha-amino acid; proline	mouse metabolite	0	0		low	0	0	0	0	0	0
diiodotyrosine	0	diiodotyrosine; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
paraoxon	0	aryl dialkyl phosphate; organophosphate insecticide	EC 3.1.1.7 (acetylcholinesterase) inhibitor; mouse metabolite	0	0		low	0	0	0	0	0	0
aminoimidazole carboxamide	0	aminoimidazole; monocarboxylic acid amide	mouse metabolite	0	0		low	0	0	0	0	0	0
methyl-4-tyramine	0	tyramines	mouse metabolite	0	0		low	0	0	0	0	0	0
citrulline	0	amino acid zwitterion; citrulline	Daphnia magna metabolite; EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; protective agent; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
lithocholic acid	0	bile acid; C24-steroid; monohydroxy-5beta-cholanic acid	geroprotector; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
chenodeoxycholic acid	0	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phosphoadenosine phosphosulfate	0	acyl sulfate; adenosine bisphosphate; purine ribonucleoside bisphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
adenosine phosphosulfate	0	acyl monophosphate; acyl sulfate; adenosine 5'-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
fructose-1,6-diphosphate	0	D-fructofuranose 1,6-bisphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
androstenediol	0	17beta-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid	androgen; human metabolite; mouse metabolite; radiation protective agent	0	0		low	0	0	0	0	0	0
dihydrotestosterone	0	17beta-hydroxy steroid; 17beta-hydroxyandrostan-3-one; 3-oxo-5alpha-steroid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
pyridoxamine dihydrochloride	0	hydrochloride; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
hydroxyhydroquinone	0	benzenetriol	mouse metabolite	0	0		low	0	0	0	0	0	0
18-hydroxycorticosterone	0	11beta-hydroxy steroid; 18-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo steroid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,2-dihydroxynaphthalene	0	naphthalenediol	mouse metabolite	0	0		low	0	0	0	0	0	0
galactitol	0	hexitol	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-hydroxyphenylacetic acid	0	hydroxy monocarboxylic acid; phenols	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
propiolaldehyde	0	terminal acetylenic compound; ynal	mouse metabolite	0	0		low	0	0	0	0	0	0
dehydroepiandrosterone sulfate	0	17-oxo steroid; steroid sulfate	EC 2.7.1.33 (pantothenate kinase) inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phenylphosphate	0	aryl phosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
n-cyclohexylformamide	0	alicyclic compound; formamides	mouse metabolite	0	0		low	0	0	0	0	0	0
deoxycytidine	0	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
deoxyuridine	0	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyadenosine	0	purine 2'-deoxyribonucleoside; purines 2'-deoxy-D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
cytidine diphosphate choline	2	nucleotide-(amino alcohol)s; phosphocholines	human metabolite; mouse metabolite; neuroprotective agent; psychotropic drug; Saccharomyces cerevisiae metabolite	1981	2002	32.5	low	0	1	0	1	0	0
deoxycytidine monophosphate	0	2'-deoxycytidine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-monophosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
nicotinamide mononucleotide	0	nicotinamide mononucleotide	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dihydroferulic acid	0	guaiacols; monocarboxylic acid; phenylpropanoid	antioxidant; human xenobiotic metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyadenosine triphosphate	0	2'-deoxyadenosine 5'-phosphate; purine 2'-deoxyribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
perillaldehyde	0	aldehyde; olefinic compound	human metabolite; mouse metabolite; volatile oil component	0	0		low	0	0	0	0	0	0
fucose	4	fucopyranose; L-fucose	Escherichia coli metabolite; mouse metabolite	1977	2017	32.2	low	0	2	1	0	1	0
uridine diphosphate glucuronic acid	0	UDP-D-glucuronic acid	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
uridine diphosphate galactose	2	UDP-D-galactose	mouse metabolite	1979	1996	36.5	low	0	1	1	0	0	0
1-naphthalenemethanol	0	naphthylmethanol	mouse metabolite	0	0		low	0	0	0	0	0	0
diadenosine tetraphosphate	0	diadenosyl tetraphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
d-glutamate	0	D-alpha-amino acid; glutamic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hydroiodic acid	0	gas molecular entity; hydrogen halide; mononuclear parent hydride	mouse metabolite	0	0		low	0	0	0	0	0	0
iron	0	divalent metal cation; iron cation; monoatomic dication	cofactor; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
trichloroepoxyethane	0	epoxide	mouse metabolite	0	0		low	0	0	0	0	0	0
ursodeoxycholic acid	0	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
glutamic acid	2	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical	2006	2007	17.5	low	0	0	0	2	0	0
adenosine diphosphate ribose	0	ADP-sugar	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
acetylgalactosamine	1	N-acetyl-D-hexosamine; N-acetylgalactosamine	Escherichia coli metabolite; human metabolite; mouse metabolite	1983	1983	41.0	low	0	1	0	0	0	0
phosphopantothenic acid	0	amidoalkyl phosphate	Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
cyromazine	0	triamino-1,3,5-triazine	mouse metabolite; triazine insecticide	0	0		low	0	0	0	0	0	0
glucose, (beta-d)-isomer	1	D-glucopyranose	epitope; mouse metabolite	1981	1981	43.0	low	0	1	0	0	0	0
xanthosine	0	purines D-ribonucleoside; xanthosines	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
thymidine 5'-triphosphate	0	pyrimidine 2'-deoxyribonucleoside 5'-triphosphate; thymidine phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyuridylic acid	0	deoxyuridine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-monophosphate	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-acetylaspartic acid	0	N-acetyl-L-amino acid; N-acyl-L-aspartic acid	antioxidant; human metabolite; mouse metabolite; nutraceutical; rat metabolite	0	0		low	0	0	0	0	0	0
deoxyuridine triphosphate	0	deoxyuridine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-triphosphate	Arabidopsis thaliana metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
homocitrulline	0	amino acid zwitterion; L-lysine derivative; non-proteinogenic L-alpha-amino acid; ureas	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2'-deoxycytidine 5'-triphosphate	0	2'-deoxycytidine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-triphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
aica ribonucleotide	0	1-(phosphoribosyl)imidazolecarboxamide; aminoimidazole	cardiovascular drug; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
obtusifoliol	0	14alpha-methyl steroid; 3beta-sterol	mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
glutathione disulfide	0	glutathione derivative; organic disulfide	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
lathosterol	0	3beta-sterol; C27-steroid; cholestanoid; Delta(7)-sterol	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-methoxyestradiol	0	17beta-hydroxy steroid; 3-hydroxy steroid	angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3'-cmp	0	cytidine 3'-phosphate; pyrimidine ribonucleoside 3'-monophosphate	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cystine	0	cystine zwitterion; cystine; L-cysteine derivative; non-proteinogenic L-alpha-amino acid	EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
phenylacetylglycine	0	monocarboxylic acid amide; monocarboxylic acid; N-acylglycine	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hordenine	0	phenethylamine alkaloid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
7-methylxanthine	0	oxopurine; purine alkaloid	human xenobiotic metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
glutaurine	0	dipeptide zwitterion; dipeptide; L-glutamine derivative; sulfonic acid	anticonvulsant; anxiolytic drug; hormone; human metabolite; mammalian metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
plasmenylserine	0	O-phosphoserine	EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor; EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor; EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
cifostodine	0	2',3'-cyclic pyrimidine nucleotide	Escherichia coli metabolite; mouse metabolite; Mycoplasma genitalium metabolite	0	0		low	0	0	0	0	0	0
n'-methyl-2-pyridone-5-carboxamide	0	methylpyridines; pyridinecarboxamide; pyridone	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-methyluric acid	0	oxopurine	human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cyclopropylamine	0	primary aliphatic amine	mouse metabolite	0	0		low	0	0	0	0	0	0
5-hydroxymethylcytosine	0	aminopyrimidine; aromatic primary alcohol; nucleobase analogue; pyrimidone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2,5-dihydroxybenzaldehyde	0	dihydroxybenzaldehyde	human metabolite; mouse metabolite; Penicillium metabolite	0	0		low	0	0	0	0	0	0
6-hydroxynicotinic acid	0	monohydroxypyridine	Arabidopsis thaliana metabolite; human urinary metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
xanthosine 5'-triphosphate	0	purine ribonucleoside 5'-monophosphate; xanthosine 5'-phosphate	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-naphthalenemethanol	0	naphthylmethanol	mouse metabolite; xenobiotic metabolite	0	0		low	0	0	0	0	0	0
hydroxyindoleacetaldehyde	0	hydroxyindoles; indoleacetaldehyde	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
xanthurenic acid 8-methyl ether	0	aromatic ether; monohydroxyquinoline; quinolinemonocarboxylic acid	carcinogenic agent; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
glucose	0	D-glucopyranose	mouse metabolite	0	0		low	0	0	0	0	0	0
1,3,7-trimethylurate	0	oxopurine	human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-methylxanthine	0	1-methylxanthine	mouse metabolite	0	0		low	0	0	0	0	0	0
3,7-dimethyluric acid	0	oxopurine	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
biocytin	0	azabicycloalkane; L-alpha-amino acid zwitterion; L-lysine derivative; monocarboxylic acid amide; non-proteinogenic L-alpha-amino acid; thiabicycloalkane; ureas	mouse metabolite	0	0		low	0	0	0	0	0	0
d-aspartic acid	0	aspartic acid; D-alpha-amino acid	mouse metabolite	0	0		low	0	0	0	0	0	0
3,4-dihydroxymandelic acid	0	2-hydroxy monocarboxylic acid; catechols	antioxidant; drug metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
coenzyme a	0	adenosine 3',5'-bisphosphate	coenzyme; Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
17-alpha-hydroxypregnenolone	0	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid; hydroxypregnenolone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
mephentermine	0	2-aminooctadecane-1,3-diol	EC 2.7.11.13 (protein kinase C) inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3,4-dihydroxyphenylglycol	0	catechols; tetrol	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
homocysteine	0	amino acid zwitterion; homocysteine; serine family amino acid	fundamental metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,7-dimethyluric acid	0	oxopurine	human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
24-methylenecholesterol	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol	mouse metabolite	0	0		low	0	0	0	0	0	0
succinyl-coenzyme a	0	omega-carboxyacyl-CoA	Escherichia coli metabolite; inhibitor; mouse metabolite	0	0		low	0	0	0	0	0	0
acetoacetyl coa	0	3-oxo-fatty acyl-CoA	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2,8-dihydroxyadenine	0	6-aminopurines; diol; heteroaryl hydroxy compound; oxopurine	human urinary metabolite; mammalian metabolite; mouse metabolite; nephrotoxic agent	0	0		low	0	0	0	0	0	0
5beta-pregnane-3,20-dione	0	20-oxo steroid; 3-oxo-5beta-steroid; C21-steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
zymosterol	0	3beta-sterol; cholestanoid	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
propionyl-coenzyme a	0	acyl-CoA	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
21-deoxycortisol	0	11beta-hydroxy steroid; 17alpha-hydroxy-C21-steroid; deoxycortisol; tertiary alpha-hydroxy ketone	human blood serum metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5,6-dihydrothymine	0	pyrimidone	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
stearoyl-coenzyme a	0	11,12-saturated fatty acyl-CoA; long-chain fatty acyl-CoA	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
imidazoleacetic acid	0	imidazoles; monocarboxylic acid	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-hydroxyphenanthrene	0	phenanthrol	mouse metabolite	0	0		low	0	0	0	0	0	0
2,5-dihydroxypyridine	0	dihydroxypyridine	mouse metabolite	0	0		low	0	0	0	0	0	0
cerium	0	cholesteryl ester	mouse metabolite	0	0		low	0	0	0	0	0	0
zymostenol	0	3beta-sterol; cholestanoid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
16-hydroxydehydroepiandrosterone	0	16alpha-hydroxy steroid; 17-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; androstanoid; secondary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
6,6-dimethyl-2-methylenebicyclo(3.1.1)heptan-3-ol	0	carbobicyclic compound; pinane monoterpenoid; secondary alcohol	GABA modulator; mouse metabolite; plant metabolite; volatile oil component	0	0		low	0	0	0	0	0	0
hydrogen sulfite	0	sulfur oxoanion	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
ecgonine methyl ester	0	methyl ester; tertiary amino compound; tropane alkaloid	analgesic; central nervous system depressant; metabolite; mouse metabolite; opioid analgesic; peripheral nervous system drug	0	0		low	0	0	0	0	0	0
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	0	hydroxylamine; imidazopyridine	carcinogenic agent; genotoxin; human xenobiotic metabolite; mouse metabolite; mutagen; neurotoxin; rat metabolite	0	0		low	0	0	0	0	0	0
fructose 2,6-diphosphate	0	D-fructofuranose 2,6-bisphosphate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cholest-5-en-3 beta,7 alpha-diol	0	3beta-hydroxy-Delta(5)-steroid; 7alpha-hydroxy steroid; oxysterol	mouse metabolite	0	0		low	0	0	0	0	0	0
hypotaurine	0	aminosulfinic acid; zwitterion	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
s-chloromethylglutathione	0	organochlorine compound; S-substituted glutathione	alkylating agent; bacterial xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-acetylamino-6-formylamino-3-methyluracil	0	formamidopyrimidine	mouse metabolite	0	0		low	0	0	0	0	0	0
anserine	0	beta-alanine derivative; dipeptide; zwitterion	animal metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5,6-dihydroxyindole	0	dihydroxyindole	mouse metabolite	0	0		low	0	0	0	0	0	0
androsterone glucuronide	0	beta-D-glucosiduronic acid; steroid glucosiduronic acid	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
estrone-3-glucuronide	0	17-oxo steroid; beta-D-glucosiduronic acid; steroid glucosiduronic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3,4-dihydroxyphenylacetaldehyde	0	alpha-CH2-containing aldehyde; catechols; phenylacetaldehydes	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5,6-dihydroxy-2-indolylcarboxylic acid	0	dihydroxyindole	mouse metabolite	0	0		low	0	0	0	0	0	0
protoporphyrinogen	0	porphyrinogens	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
inositol-3,4,5,6-tetrakisphosphate	0	myo-inositol tetrakisphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
(20s)-20-hydroxycholesterol	0	20-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid; oxysterol	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
24-hydroxycholesterol	0	24-hydroxycholesterol	biomarker; human blood serum metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
phytosphingosine	0	amino alcohol; sphingoid; triol	mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
butyryl-coenzyme a	0	butanoyl-CoAs	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-acetylputrescine	0	N-monoacetylalkane-alpha,omega-diamine; N-substituted putrescine	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
erythrose 4-phosphate	0	erythrose phosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cdp ethanolamine	0	nucleotide-(amino alcohol)s; phosphoethanolamine	mouse metabolite	0	0		low	0	0	0	0	0	0
7 alpha-hydroxy-4-cholesten-3-one	0	3-oxo-Delta(4) steroid; 7alpha-hydroxy steroid; cholestanoid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
galactose-1-phosphate	0	alpha-D-hexose 1-phosphate; D-galactopyranose 1-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
gamma-glutamylcysteine	0	gamma-glutamylcysteine	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
27-hydroxycholesterol	0	26-hydroxycholesterol	apoptosis inducer; human metabolite; mouse metabolite; neuroprotective agent	0	0		low	0	0	0	0	0	0
dehydroalanine	0	2,3-dehydroamino acid; alpha,beta-unsaturated monocarboxylic acid; amino acid zwitterion; enamine; non-proteinogenic alpha-amino acid	alkylating agent; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine	0	1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; phosphatidylcholine 30:0; tetradecanoate ester	mouse metabolite	0	0		low	0	0	0	0	0	0
proline	0	amino acid zwitterion; glutamine family amino acid; L-alpha-amino acid; proline; proteinogenic amino acid	algal metabolite; compatible osmolytes; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
d-glutamine	0	amino acid zwitterion; D-alpha-amino acid; glutamine	mouse metabolite	0	0		low	0	0	0	0	0	0
diquafosol	0	pyrimidine ribonucleoside 5'-tetraphosphate; uridine 5'-phosphate	mouse metabolite; P2Y2 receptor agonist	0	0		low	0	0	0	0	0	0
2'-deoxycytidine diphosphate	0	2'-deoxycytidine phosphate; pyrimidine 2'-deoxyribonucleoside 5'-diphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	0	0		low	0	0	0	0	0	0
19-hydroxytestosterone	0	17beta-hydroxy steroid; 19-hydroxy steroid; 3-oxo-Delta(4) steroid	mouse metabolite	0	0		low	0	0	0	0	0	0
2-hydroxy-1,4-benzoquinone	0	monohydroxy-1,4-benzoquinones	mouse metabolite	0	0		low	0	0	0	0	0	0
3,4-dihydroxyphenylglycolaldehyde	0	catechols; hydroxyaldehyde	human metabolite; mouse metabolite; neurotoxin	0	0		low	0	0	0	0	0	0
sorbitol 6-phosphate	0	alditol 6-phosphate; glucitol phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
adenosine 3'-phosphate-5'-phosphate	0	adenosine bisphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
androsterone sulfate	0	17-oxo steroid; androstanoid; steroid sulfate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
alpha-ribazole	0	1-ribosylbenzimidazole; dimethylbenzimidazole	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3,7,12-trihydroxycoprostane	0	12alpha-hydroxy steroid; 3alpha-hydroxy steroid; 7alpha-hydroxy steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
saccharopine	0	amino acid opine; L-lysine derivative	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
allysine	0	allysine; amino acid zwitterion; aminoadipate semialdehyde; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
orotidylic acid	0	pyrimidine ribonucleoside 5'-monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
beta-ureidoisobutyric acid	0	ureidocarboxylic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
saicar	0	1-(phosphoribosyl)imidazolecarboxamide	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
kynurenine	0	amino acid zwitterion; kynurenine; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
thymidine 5'-diphosphate	0	pyrimidine 2'-deoxyribonucleoside 5'-diphosphate; thymidine phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hydromethylthionine	0	aromatic amine; phenothiazines; tertiary amino compound	bacterial xenobiotic metabolite; fluorochrome; mouse metabolite; rat metabolite	0	0		low	0	0	0	0	0	0
5-hydroxykynuramine	0	hydroxykynurenamine; primary amino compound	mouse metabolite	0	0		low	0	0	0	0	0	0
sedoheptulose 1,7-bisphosphate	0	ketoheptose phosphate; sedoheptulose derivative	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
sedoheptulose 7-phosphate	0	ketoheptose phosphate; sedoheptulose derivative	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
thiocysteine	0	amino acid zwitterion; S-substituted L-cysteine	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
diadenosine triphosphate	0	diadenosyl triphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
carboxyaminoimidazole ribotide	0	1-(phosphoribosyl)imidazole; aminoimidazole; imidazole-4-carboxylic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
isovaleryl-coenzyme a	0	methylbutanoyl-CoA; short-chain fatty acyl-CoA	mouse metabolite	0	0		low	0	0	0	0	0	0
lauroyl-coenzyme a	0	medium-chain fatty acyl-CoA	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
nicotinic acid adenine dinucleotide	0	nicotinic acid dinucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol	0	3beta-sterol	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
phenylacetyl-coenzyme a	0	acyl-CoA	Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-formamidoimidazole-4-carboxamide ribotide	0	1-(phosphoribosyl)imidazolecarboxamide	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
biotin	4	biotins; vitamin B7	coenzyme; cofactor; Escherichia coli metabolite; fundamental metabolite; human metabolite; mouse metabolite; nutraceutical; prosthetic group; Saccharomyces cerevisiae metabolite	1989	2010	27.8	low	0	1	2	1	0	0
campesterol	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; C28-steroid; phytosterols	mouse metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyadenosine triphosphate	0	2'-deoxyadenosine 5'-phosphate; purine 2'-deoxyribonucleoside 5'-diphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cholestane-3,7,12,26-tetrol	0	12alpha-hydroxy steroid; 26-hydroxy steroid; 3alpha-hydroxy steroid; 7alpha-hydroxy steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
gamma-glutamyl phosphate	0	gamma-glutamyl phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-amino-6-ribitylamino-2,4-(1h,3h)pyrimidinedione	0	aminouracil; hydroxypyrimidine	Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
cholic acid	1	12alpha-hydroxy steroid; 3alpha-hydroxy steroid; 7alpha-hydroxy steroid; bile acid; C24-steroid; trihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	1989	1989	35.0	low	0	1	0	0	0	0
sitosterol, (3beta)-isomer	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; C29-steroid; phytosterols; stigmastane sterol	anticholesteremic drug; antioxidant; mouse metabolite; plant metabolite; sterol methyltransferase inhibitor	0	0		low	0	0	0	0	0	0
cortisone	0	11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
androstane-3,17-dione, (5alpha)-isomer	0	3-oxo-5alpha-steroid; androstane-3,17-dione	mouse metabolite	0	0		low	0	0	0	0	0	0
cholesteryl palmitate	0	cholesteryl ester	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
lanosterol	0	14alpha-methyl steroid; 3beta-sterol; tetracyclic triterpenoid	bacterial metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
21-hydroxypregnenolone	0	21-hydroxy steroid; hydroxypregnenolone; primary alpha-hydroxy ketone	mouse metabolite	0	0		low	0	0	0	0	0	0
2-hydroxyestradiol	0	17beta-hydroxy steroid; 2-hydroxy steroid	carcinogenic agent; human metabolite; metabolite; mouse metabolite; prodrug	0	0		low	0	0	0	0	0	0
epietiocholanolone	0	17-oxo steroid; 3beta-hydroxy steroid; androstanoid	androgen; animal metabolite; human blood serum metabolite; mouse metabolite; rat metabolite	0	0		low	0	0	0	0	0	0
5-hydroxyisourate	0	oxopurine	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
19-hydroxy-4-androstene-3,17-dione	0	17-oxo steroid; 19-hydroxy steroid; 3-oxo steroid; androstanoid	mouse metabolite	0	0		low	0	0	0	0	0	0
taurochenodeoxycholic acid	0	bile acid taurine conjugate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
glyceraldehyde 3-phosphate	0	glyceraldehyde 3-phosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
5'-methylthioadenosine	0	thioadenosine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
5'-deoxyadenosine	0	5'-deoxyribonucleoside; adenosines	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
ribulose 5-phosphate	0	ribulose 5-phosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
xylulose-5-phosphate, (d)-isomer	0	xylulose 5-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
glycerate 1,3-biphosphate	0	2,3-bisphosphoglyceric acid; acyl monophosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
isomaltose	0	glycosylglucose	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
arabinose	0	L-arabinose	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-acetylneuraminic acid	60	N-acetylneuraminic acids	antioxidant; bacterial metabolite; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; human metabolite; mouse metabolite	1984	2023	22.5	low	1	8	24	17	8	3
glucosamine	5	D-glucosamine	Escherichia coli metabolite; geroprotector; mouse metabolite	1977	2000	35.6	low	0	2	3	0	0	0
carnosine	0	amino acid zwitterion; dipeptide	anticonvulsant; antineoplastic agent; antioxidant; Daphnia magna metabolite; geroprotector; human metabolite; mouse metabolite; neuroprotective agent	0	0		low	0	0	0	0	0	0
raffinose	0	raffinose family oligosaccharide; trisaccharide	mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
5-hydroxytryptophan	0	5-hydroxytryptophan; amino acid zwitterion; hydroxy-L-tryptophan; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
xanthosine 5'-triphosphate	0	purine ribonucleoside 5'-triphosphate; xanthosine 5'-phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dopaquinone	0	1,2-benzoquinones; amino acid zwitterion; L-phenylalanine derivative	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
pantetheine	0	pantetheines; thiol	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
galactose	0	D-galactopyranose	epitope; mouse metabolite	0	0		low	0	0	0	0	0	0
galactose	0	D-galactopyranose	mouse metabolite	0	0		low	0	0	0	0	0	0
s-adenosyl-3-methylthiopropylamine	0	adenosines; sulfonium compound	Escherichia coli metabolite; human urinary metabolite; mouse metabolite; rat metabolite	0	0		low	0	0	0	0	0	0
5-diphosphomevalonic acid	0	carboxyalkyl phosphate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
7-dehydrocholesterol	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; cholestanoid; Delta(5),Delta(7)-sterol	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
6-phosphonoglucono-delta-lactone	0	aldonolactone phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
inositol 1,4,5-trisphosphate	0	myo-inositol trisphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
stachyose	0	raffinose family oligosaccharide; tetrasaccharide	mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
desmosterol	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; C27-steroid; cholestanoid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
monoiodotyrosine	0	amino acid zwitterion; L-tyrosine derivative; monoiodotyrosine; non-proteinogenic L-alpha-amino acid	EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n'-formylkynurenine	0	amino acid zwitterion; N-formylkynurenine; non-proteinogenic amino acid derivative; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
ketodihydrosphingosine	0	2-amino-1-hydroxyoctadecan-3-one	mouse metabolite	0	0		low	0	0	0	0	0	0
nicotinamide-beta-riboside	0	N-glycosylnicotinamide; pyridine nucleoside	geroprotector; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
4-hydroxyphenylacetaldehyde	0	alpha-CH2-containing aldehyde; phenylacetaldehydes	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
androstane-3,17-dione, (5beta)-isomer	0	3-oxo-5beta-steroid; androstane-3,17-dione	mouse metabolite	0	0		low	0	0	0	0	0	0
trimethyllysine	0	alpha-amino-acid cation	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
inositol 3,4-bisphosphate	0	myo-inositol bisphosphate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-acetylglucosamine-1-phosphate	0	N-acetyl-D-glucosamine 1-phosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
pantothenylcysteine 4'-phosphate	0	L-cysteine derivative	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
24,25-dihydrolanosterol	0	3beta-sterol; tetracyclic triterpenoid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-methoxyestrone	0	17-oxo steroid; 3-hydroxy steroid; alicyclic ketone; aromatic ether; phenolic steroid; phenols	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dehydroascorbic acid	0	dehydroascorbic acid; vitamin C	coenzyme; mouse metabolite	0	0		low	0	0	0	0	0	0
cortodoxone	0	deoxycortisol; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
estradiol-3-glucuronide	0	17beta-hydroxy steroid; beta-D-glucosiduronic acid; steroid glucosiduronic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
beta-sulfopyruvic acid	0	carboxyalkanesulfonic acid	mouse metabolite	0	0		low	0	0	0	0	0	0
acetyl adenylate	0	5'-acylphosphoadenosin	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
2-hydroxypropylphosphonic acid	0	phosphonic acids; secondary alcohol	mouse metabolite	0	0		low	0	0	0	0	0	0
4,4-dimethylcholesta-8,14,24-trienol	0	3beta-sterol; Delta(14) steroid	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
inositol-1,4,5,6-tetrakisphosphate	0	myo-inositol tetrakisphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
maleic acid	0	butenedioic acid	algal metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
dephosphocoenzyme a	0	adenosine 5'-phosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
arachidonic acid	3	icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid	Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite	1988	1994	32.7	low	0	1	2	0	0	0
n(1)-(5-phosphoribosyl)-5,6-dimethylbenzimidazole	0	1-ribosylbenzimidazole; dimethylbenzimidazole; ribose monophosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
prostaglandin h2	0	olefinic compound; oxylipin; prostaglandins H; secondary alcohol	mouse metabolite	0	0		low	0	0	0	0	0	0
3-hydroxy-3-methylglutaryl-coenzyme a	0	3-hydroxy-3-methylglutaryl-CoA; 3-hydroxy fatty acyl-CoA	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
retinol	1	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite	1978	1978	46.0	low	0	1	0	0	0	0
docosahexaenoate	0	docosahexaenoic acid; omega-3 fatty acid	algal metabolite; antineoplastic agent; Daphnia tenebrosa metabolite; human metabolite; mouse metabolite; nutraceutical	0	0		low	0	0	0	0	0	0
oleic acid	1	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent	1991	1991	33.0	low	0	0	1	0	0	0
farnesyl pyrophosphate	0	farnesyl diphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
geranyl pyrophosphate	0	polyprenyl diphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,5-dihydro-fad	0	flavin adenine dinucleotide	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cocaine	0	benzoate ester; methyl ester; tertiary amino compound; tropane alkaloid	adrenergic uptake inhibitor; central nervous system stimulant; dopamine uptake inhibitor; environmental contaminant; local anaesthetic; mouse metabolite; plant metabolite; serotonin uptake inhibitor; sodium channel blocker; sympathomimetic agent; vasoconstrictor agent; xenobiotic	0	0		low	0	0	0	0	0	0
eicosapentaenoic acid	0	icosapentaenoic acid; omega-3 fatty acid	anticholesteremic drug; antidepressant; antineoplastic agent; Daphnia galeata metabolite; fungal metabolite; micronutrient; mouse metabolite; nutraceutical	0	0		low	0	0	0	0	0	0
s-hydroxymethylglutathione	0	S-substituted glutathione	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
geranylgeranyl pyrophosphate	0	geranylgeranyl diphosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
cytidine monophosphate n-acetylneuraminic acid	2	CMP-N-acyl-beta-neuraminic acid	mouse metabolite	1977	1989	41.0	low	0	2	0	0	0	0
prostaglandin d2	0	prostaglandins D	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
hexanoyl-coenzyme a	0	medium-chain fatty acyl-CoA	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
4-phosphoerythronate	0	4-phosphoerythronic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
colfosceril palmitate	0	1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; phosphatidylcholine 32:0	mouse metabolite; surfactant	0	0		low	0	0	0	0	0	0
lyso-pc	0	1-O-acyl-sn-glycero-3-phosphocholine; lysophosphatidylcholine 16:0	mouse metabolite	0	0		low	0	0	0	0	0	0
riboflavin	0	flavin; vitamin B2	anti-inflammatory agent; antioxidant; cofactor; Escherichia coli metabolite; food colouring; fundamental metabolite; human urinary metabolite; mouse metabolite; photosensitizing agent; plant metabolite	0	0		low	0	0	0	0	0	0
trans-4-coumaric acid	0	4-coumaric acid	food component; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
retinaldehyde	0	retinal; vitamin A	gap junctional intercellular communication inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
squalene	0	triterpene	human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
flavin-adenine dinucleotide	0	flavin adenine dinucleotide; vitamin B2	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; prosthetic group	0	0		low	0	0	0	0	0	0
flavin mononucleotide	0	flavin mononucleotide; vitamin B2	bacterial metabolite; coenzyme; cofactor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
3-hydroxybutyryl-coenzyme a	0	3-hydroxyacyl-CoA; hydroxybutanoyl-CoA	mouse metabolite	0	0		low	0	0	0	0	0	0
malonyl coenzyme a	0	malonyl-CoAs	EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor; Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
palmitoyl coenzyme a	0	11,12-saturated fatty acyl-CoA; 3-substituted propionyl-CoA; long-chain fatty acyl-CoA; palmitoyl bioconjugate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dihydrosphingosine 1-phosphate	0	sphingoid 1-phosphate	mouse metabolite	0	0		low	0	0	0	0	0	0
glycerylphosphorylcholine	0	phosphocholines; sn-glycerol 3-phosphates	Escherichia coli metabolite; human metabolite; mouse metabolite; neuroprotective agent; parasympatholytic; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
caffeic acid	0	caffeic acid	geroprotector; mouse metabolite	0	0		low	0	0	0	0	0	0
coniferyl alcohol	0	guaiacols; phenylpropanoid	animal metabolite; monolignol; mouse metabolite; pheromone; plant metabolite; volatile oil component	0	0		low	0	0	0	0	0	0
cysteine sulfinic acid	0	organosulfinic acid; S-substituted L-cysteine	Escherichia coli metabolite; human metabolite; metabotropic glutamate receptor agonist; mouse metabolite	0	0		low	0	0	0	0	0	0
estrone sulfate	0	17-oxo steroid; steroid sulfate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
raphanusamic acid	0	thiazolidinemonocarboxylic acid	Arabidopsis thaliana metabolite; mouse metabolite; xenobiotic metabolite	0	0		low	0	0	0	0	0	0
isobutyryl-coenzyme a	0	methyl-branched fatty acyl-CoA; short-chain fatty acyl-CoA	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dihydroxycoprostane	0	3alpha-hydroxy steroid; 7alpha-hydroxy steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
glutaryl-coenzyme a	0	glutaryl-CoAs	mouse metabolite	0	0		low	0	0	0	0	0	0
sphingosine	15	sphing-4-enine	human metabolite; mouse metabolite	1977	2021	25.5	low	0	3	7	3	1	1
bilirubin	0	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dinoprostone	2	prostaglandins E	human metabolite; mouse metabolite; oxytocic	1993	2003	26.0	low	0	0	1	1	0	0
dinoprost	0	monocarboxylic acid; prostaglandins Falpha	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
leukotriene a4	0	epoxy fatty acid; leukotriene; long-chain fatty acid; oxylipin; polyunsaturated fatty acid	human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
calcitriol	2	D3 vitamins; hydroxycalciol; triol	antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical	1986	1989	36.5	low	0	2	0	0	0	0
beta carotene	0	carotenoid beta-end derivative; cyclic carotene	antioxidant; biological pigment; cofactor; ferroptosis inhibitor; human metabolite; mouse metabolite; plant metabolite; provitamin A	0	0		low	0	0	0	0	0	0
11-cis-retinal	0	retinal	chromophore; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
leukotriene b4	0	dihydroxy monocarboxylic acid; hydroxy polyunsaturated fatty acid; leukotriene; long-chain fatty acid	human metabolite; mouse metabolite; plant metabolite; vasoconstrictor agent	0	0		low	0	0	0	0	0	0
leukotriene c4	0	leukotriene	bronchoconstrictor agent; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
thromboxane a2	0	epoxy monocarboxylic acid; thromboxanes A	mouse metabolite	0	0		low	0	0	0	0	0	0
15-hydroxy-5,8,11,13-eicosatetraenoic acid	0	(5Z,8Z,11Z,13E)-15-HETE	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-hydroxy-6,8,11,14-eicosatetraenoic acid	0	HETE	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
arachidonic acid 5-hydroperoxide	0	5-HPETE	mouse metabolite	0	0		low	0	0	0	0	0	0
leukotriene d4	0	dipeptide; leukotriene; organic sulfide	bronchoconstrictor agent; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
prostaglandin g2	0	prostaglandins G	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
6-ketoprostaglandin f1 alpha	1	prostaglandins Falpha	human metabolite; mouse metabolite	1993	1993	31.0	low	0	0	1	0	0	0
arachidonic acid omega-9 hydroperoxide	0	HPETE	mouse metabolite	0	0		low	0	0	0	0	0	0
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid, (s)-(e,z,z,z)-isomer	0	15-HPETE	mouse metabolite	0	0		low	0	0	0	0	0	0
gamma-linolenic acid	0	linolenic acid; omega-6 fatty acid	human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
alpha-linolenic acid	0	linolenic acid; omega-3 fatty acid	micronutrient; mouse metabolite; nutraceutical	0	0		low	0	0	0	0	0	0
1-palmitoyl-2-oleoyl-sn-glycerol	0	1,2-diacyl-sn-glycerol; 1-palmitoyl-2-oleoylglycerol	mouse metabolite	0	0		low	0	0	0	0	0	0
epoprostenol	0	prostaglandins I	mouse metabolite	0	0		low	0	0	0	0	0	0
9-hydroxy-10,12-octadecadienoic acid	0	HODE; octadecadienoic acid	human metabolite; metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
thromboxane b2	1	thromboxanes B	human metabolite; mouse metabolite	1993	1993	31.0	low	0	0	1	0	0	0
thromboxane b3	0	thromboxanes B	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
11,12-dihydroxyeicosatrienoic acid	0	DHET	mouse metabolite	0	0		low	0	0	0	0	0	0
14,15-dihydroxyeicosatrienoic acid	0	DHET; diol; secondary allylic alcohol	mouse metabolite	0	0		low	0	0	0	0	0	0
20-hydroxy-5,8,11,14-eicosatetraenoic acid	0	HETE; hydroxy monocarboxylic acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5-oxo-6,8,11,14-eicosatetraenoic acid	0	oxoicosatetraenoic acid	human metabolite; immunomodulator; mouse metabolite	0	0		low	0	0	0	0	0	0
5,6-epoxy-8,11,14-eicosatrienoic acid	0	EET	mouse metabolite	0	0		low	0	0	0	0	0	0
8,9-epoxyeicosatrienoic acid	0	EET	mouse metabolite	0	0		low	0	0	0	0	0	0
1-palmitoyl-2-oleoylphosphatidylethanolamine, (z & r)-isomer	0	1,2-diacyl-sn-glycero-3-phosphoethanolamine; phosphatidylethanolamine 34:1 zwitterion; phosphatidylethanolamine	mouse metabolite	0	0		low	0	0	0	0	0	0
sphingosine 1-phosphate	0	sphingoid 1-phosphate	mouse metabolite; signalling molecule; sphingosine-1-phosphate receptor agonist; T-cell proliferation inhibitor; vasodilator agent	0	0		low	0	0	0	0	0	0
cholesteryl oleate	0	CE(18:1); cholesteryl octadec-9-enoate	mouse metabolite	0	0		low	0	0	0	0	0	0
calcifediol	0	D3 vitamins; diol; hydroxycalciol	bone density conservation agent; human metabolite; metabolite; mouse metabolite; nutraceutical	0	0		low	0	0	0	0	0	0
hyodeoxycholic acid	0	5beta-cholanic acids; 6alpha,20xi-murideoxycholic acid; bile acid; C24-steroid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cerium	0	CE(18:2); cholesteryl octadeca-9,12-dienoate	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
xylulose	0	xylulose	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
11-dehydrocorticosterone	0	11-oxo steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; corticosteroid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
stearidonic acid	0	long-chain fatty acid; octadecatetraenoic acid; omega-3 fatty acid	Daphnia galeata metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
trilinolein	0	1,2-diacyl-3-linoleoylglycerol; 1,3-diacyl-2-linoleoylglycerol; linoleoyl containing 1,2,3-triacyl-sn-glycerol; TG(18:2/18:2/18:2); triglyceride	mouse metabolite	0	0		low	0	0	0	0	0	0
dimyristoylphosphatidylcholine	4	1,2-diacyl-sn-glycero-3-phosphocholine; phosphatidylcholine 28:0; tetradecanoate ester	antigen; mouse metabolite	1993	2011	25.2	low	0	0	3	0	1	0
2,3-oxidosqualene	0	2,3-epoxysqualene	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
deoxyribose	0	deoxypentose	human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
monodehydroascorbate	0	organic radical	mouse metabolite	0	0		low	0	0	0	0	0	0
oleoyl-coenzyme a	0	octadecenoyl-CoA	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
vitamin a2	0	retinoid; vitamin A	human xenobiotic metabolite; marine xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1,2-dioleoylphosphatidylserine	0	phosphatidylserine(18:1/18:1)	mouse metabolite	0	0		low	0	0	0	0	0	0
5-hydroxy-6,8,11,14,17-eicosapentaenoic acid	0	HEPE	mouse metabolite	0	0		low	0	0	0	0	0	0
1-stearoyl-2-linoleoylphosphatidylcholine	0	phosphatidylcholine 36:2	mouse metabolite	0	0		low	0	0	0	0	0	0
1-stearoyl-2-linoleoyl-sn-glycerol	0	1,2-diacyl-sn-glycerol; diacylglycerol 36:2	mouse metabolite	0	0		low	0	0	0	0	0	0
1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine	0	phosphatidylcholine 38:6	mouse metabolite	0	0		low	0	0	0	0	0	0
13(S)-HODE	0	HODE	antineoplastic agent; human xenobiotic metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
1-stearoyl-2-oleoyl-sn-glycerol	0	1,2-diacyl-sn-glycerol; 1-stearoyl-2-oleoylglycerol; diacylglycerol 36:1	mouse metabolite	0	0		low	0	0	0	0	0	0
1-palmitoyl-2-palmitoleoyl-sn-glycero-3-phosphocholine	0	1-acyl-2-palmitoleoyl-sn-glycero-3-phosphocholine; phosphatidylcholine 32:1	mouse metabolite	0	0		low	0	0	0	0	0	0
13-oxo-9,11-octadecadienoic acid	0	13-oxo-9,11-octadecadienoic acid	metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
n-stearoylsphingomyelin	0	sphingomyelin 36:1; sphingomyelin d18:1	mouse metabolite	0	0		low	0	0	0	0	0	0
20,22-dihydroxycholesterol	0	20-hydroxy steroid; 22-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; cholestanoid; oxysterol	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cholesteryl arachidonate	0	cholesteryl icosatetraenoate	antibacterial agent; mouse metabolite	0	0		low	0	0	0	0	0	0
acryloyl-coenzyme a	0	2-enoyl-CoA; monounsaturated fatty acyl-CoA	mouse metabolite	0	0		low	0	0	0	0	0	0
phosphocreatine	0	phosphagen; phosphoamino acid	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
samarium	0	sphingomyelin d18:1/16:0	mouse metabolite	0	0		low	0	0	0	0	0	0
n-palmitoylgalactosylsphingosine	0	HexCer(d18:1/16:0); N-acyl-beta-D-galactosylsphingosine	mouse metabolite	0	0		low	0	0	0	0	0	0
cytidine diphosphate choline	0	nucleotide-(amino alcohol)s; phosphocholines	human metabolite; mouse metabolite; neuroprotective agent; psychotropic drug; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
palmitoylcarnitine	0	O-palmitoylcarnitine; saturated fatty acyl-L-carnitine	EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
s-tetradecanoyl-coenzyme a	0	11,12-saturated fatty acyl-CoA; long-chain fatty acyl-CoA	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
prosomatostatin	0	heterodetic cyclic peptide; peptide hormone	fungal metabolite; mouse metabolite; rat metabolite	0	0		low	0	0	0	0	0	0
phosphatidylcholines	0	phosphatidylcholine 40:6	mouse metabolite	0	0		low	0	0	0	0	0	0
2-ketoarginine	0	2-oxo monocarboxylic acid; zwitterion	human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
cyclosporine	0	keto-disaccharide	mouse metabolite	0	0		low	0	0	0	0	0	0
cyclic gmp	0	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
diguanosine tetraphosphate	0	guanosine 5'-phosphate; purine ribonucleoside 5'-tetraphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
deoxyguanosine	0	purine 2'-deoxyribonucleoside; purines 2'-deoxy-D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
deoxyinosine	0	purine 2'-deoxyribonucleoside; purines 2'-deoxy-D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyguanosine 5'-phosphate	0	deoxyguanosine phosphate; guanyl deoxyribonucleotide; purine 2'-deoxyribonucleoside 5'-monophosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
deoxyguanosine triphosphate	0	deoxyguanosine phosphate; guanyl deoxyribonucleotide; purine 2'-deoxyribonucleoside 5'-triphosphate	Arabidopsis thaliana metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
7,8-dihydroneopterin	0	dihydropterin; neopterins	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
dihydrofolate	0	dihydrofolic acids	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
dihydroneopterin triphosphate	0	dihydropterin; neopterins; pterin phosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
deoxyinosine monophosphate	0	deoxyinosine phosphate; purine 2'-deoxyribonucleoside 5'-monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	0	0		low	0	0	0	0	0	0
2'-deoxyinosine triphosphate	0	deoxyinosine phosphate; purine 2'-deoxyribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
guanosine diphosphate	1	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	1998	1998	26.0	low	0	0	1	0	0	0
gdp-4-keto-6-deoxymannose	0	GDP-sugar	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
guanosine diphosphate mannose	0	GDP-D-mannose	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite	0	0		low	0	0	0	0	0	0
guanosine pentaphosphate	0	guanosine 5'-phosphate; guanosine bisphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
guanosine monophosphate	0	guanosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	biomarker; Escherichia coli metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
guanosine triphosphate	2	guanosine 5'-phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	1990	1998	30.0	low	0	0	2	0	0	0
guanine	0	2-aminopurines; oxopurine; purine nucleobase	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
guanosine tetraphosphate	0	guanosine bisphosphate	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
inosinic acid	0	inosine phosphate; purine ribonucleoside 5'-monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
inosine	0	inosines; purines D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	0	0		low	0	0	0	0	0	0
inosine triphosphate	0	inosine phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
folic acid	0	folic acids; N-acyl-amino acid	human metabolite; mouse metabolite; nutrient	0	0		low	0	0	0	0	0	0
dyspropterin	0	biopterins; tetrahydropterin	human metabolite; metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
leucovorin	0	formyltetrahydrofolic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
5,10-methenyltetrahydrofolate	0	methylenetetrahydrofolic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0
10-formyltetrahydrofolate	0	formyltetrahydrofolic acid	Escherichia coli metabolite; mouse metabolite	0	0		low	0	0	0	0	0	0

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
phosphoserine	2	non-proteinogenic alpha-amino acid; O-phosphoamino acid; serine derivative	human metabolite	1994	2015	19.5	low	0	0	1	0	1	0
acetic acid	2	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent	1989	2013	23.0	low	0	1	0	0	1	0
formic acid	2	monocarboxylic acid	antibacterial agent; astringent; metabolite; protic solvent; solvent	1993	1996	29.5	low	0	0	2	0	0	0
methane	3	alkane; gas molecular entity; mononuclear parent hydride; one-carbon compound	bacterial metabolite; fossil fuel; greenhouse gas	1994	2018	18.3	low	0	0	1	1	1	0
chlorine	1	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite	1993	1993	31.0	low	0	0	1	0	0	0
glycerol	1	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent	2005	2005	19.0	low	0	0	0	1	0	0
kynurenine	1	aromatic ketone; non-proteinogenic alpha-amino acid; substituted aniline	human metabolite	2014	2014	10.0	low	0	0	0	0	1	0
pyruvaldehyde	1	2-oxo aldehyde; propanals	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	2021	2021	3.0	low	0	0	0	0	0	1
methanol	2	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	1999	2009	20.0	low	0	0	1	1	0	0
nickel	1	metal allergen; nickel group element atom	epitope; micronutrient	1994	1994	30.0	low	0	0	1	0	0	0
palmitic acid	3	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite	1992	2006	26.7	low	0	0	2	1	0	0
picolinic acid	1	pyridinemonocarboxylic acid	human metabolite; MALDI matrix material	2014	2014	10.0	low	0	0	0	0	1	0
pyruvic acid	1	2-oxo monocarboxylic acid	cofactor; fundamental metabolite	2022	2022	2.0	low	0	0	0	0	0	1
quinolinic acid	1	pyridinedicarboxylic acid	Escherichia coli metabolite; human metabolite; mouse metabolite; NMDA receptor agonist	2014	2014	10.0	low	0	0	0	0	1	0
1-anilino-8-naphthalenesulfonate	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe	1992	1992	32.0	low	0	0	1	0	0	0
3-methylcholanthrene	1	ortho- and peri-fused polycyclic arene	aryl hydrocarbon receptor agonist; carcinogenic agent	1978	1978	46.0	low	0	1	0	0	0	0
theophylline	1	dimethylxanthine	adenosine receptor antagonist; anti-asthmatic drug; anti-inflammatory agent; bronchodilator agent; drug metabolite; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; fungal metabolite; human blood serum metabolite; immunomodulator; muscle relaxant; vasodilator agent	1989	1989	35.0	low	0	1	0	0	0	0
aspirin	2	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent	1992	1995	30.5	low	0	0	2	0	0	0
bay-k-8644	1	(trifluoromethyl)benzenes; C-nitro compound; dihydropyridine; methyl ester		1994	1994	30.0	low	0	0	1	0	0	0
propiolactone	1	propan-3-olide		2011	2011	13.0	low	0	0	0	0	1	0
chlorpromazine	1	organochlorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; phenothiazine antipsychotic drug	1989	1989	35.0	low	0	1	0	0	0	0
ciprofibrate	1	cyclopropanes; monocarboxylic acid; organochlorine compound	antilipemic drug	1999	1999	25.0	low	0	0	1	0	0	0
clofibric acid	1	aromatic ether; monocarboxylic acid; monochlorobenzenes	anticholesteremic drug; antilipemic drug; antineoplastic agent; herbicide; marine xenobiotic metabolite; PPARalpha agonist	1999	1999	25.0	low	0	0	1	0	0	0
valproic acid	2	branched-chain fatty acid; branched-chain saturated fatty acid	anticonvulsant; antimanic drug; EC 3.5.1.98 (histone deacetylase) inhibitor; GABA agent; neuroprotective agent; psychotropic drug; teratogenic agent	2008	2016	12.0	low	0	0	0	1	1	0
1-phenyl-2-palmitoylamino-3-morpholino-1-propanol	1	benzyl alcohols; fatty amide; morpholines; secondary alcohol; tertiary amino compound		2013	2013	11.0	low	0	0	0	0	1	0
erythrosine	1			1984	1984	40.0	low	0	1	0	0	0	0
ether	1	ether; volatile organic compound	inhalation anaesthetic; non-polar solvent; refrigerant	1996	1996	28.0	low	0	0	1	0	0	0
gentamicin	1			2010	2010	14.0	low	0	0	0	1	0	0
leflunomide	1	(trifluoromethyl)benzenes; isoxazoles; monocarboxylic acid amide	antineoplastic agent; antiparasitic agent; EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; hepatotoxic agent; immunosuppressive agent; non-steroidal anti-inflammatory drug; prodrug; pyrimidine synthesis inhibitor; tyrosine kinase inhibitor	1996	1996	28.0	low	0	0	1	0	0	0
ly 303511	2	N-arylpiperazine		2007	2007	17.0	low	0	0	0	2	0	0
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	1	chromones; morpholines; organochlorine compound	autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector	2007	2007	17.0	low	0	0	0	1	0	0
nocodazole	1	aromatic ketone; benzimidazoles; carbamate ester; thiophenes	antimitotic; antineoplastic agent; microtubule-destabilising agent; tubulin modulator	1995	1995	29.0	low	0	0	1	0	0	0
methylphenidate	1	beta-amino acid ester; methyl ester; piperidines		2011	2011	13.0	low	0	0	0	0	1	0
ethylmaleimide	1	maleimides	anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor	1990	1990	34.0	low	0	0	1	0	0	0
nicardipine	1	benzenes; C-nitro compound; diester; dihydropyridine; methyl ester; tertiary amino compound		1994	1994	30.0	low	0	0	1	0	0	0
oxidopamine	2	benzenetriol; catecholamine; primary amino compound	drug metabolite; human metabolite; neurotoxin	1985	2008	27.5	low	0	1	0	1	0	0
potassium iodide	1	potassium salt	expectorant; radical scavenger	1999	1999	25.0	low	0	0	1	0	0	0
propantheline	1	xanthenes		1989	1989	35.0	low	0	1	0	0	0	0
resorcinol	1	benzenediol; phenolic donor; resorcinols	erythropoietin inhibitor; sensitiser	1996	1996	28.0	low	0	0	1	0	0	0
w 7	1			1999	1999	25.0	low	0	0	1	0	0	0
zinc chloride	1	inorganic chloride; zinc molecular entity	astringent; disinfectant; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; Lewis acid	1993	1993	31.0	low	0	0	1	0	0	0
prednisolone	2	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; drug metabolite; environmental contaminant; immunosuppressive agent; xenobiotic	1995	2013	20.0	low	1	0	1	0	1	0
thymidine	5	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite	1984	1997	31.4	low	0	1	4	0	0	0
dextroamphetamine	1	1-phenylpropan-2-amine	adrenergic agent; adrenergic uptake inhibitor; dopamine uptake inhibitor; dopaminergic agent; neurotoxin; sympathomimetic agent	1985	1985	39.0	low	0	1	0	0	0	0
2-acetylaminofluorene	1	2-acetamidofluorenes	antimitotic; carcinogenic agent; epitope; mutagen	1978	1978	46.0	low	0	1	0	0	0	0
serine	6	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	1978	2006	29.7	low	0	2	2	2	0	0
aspartic acid	1	aspartate family amino acid; aspartic acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; mouse metabolite; neurotransmitter	2004	2004	20.0	low	0	0	0	1	0	0
lysine	2	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	1994	2007	23.5	low	0	0	1	1	0	0
ethinyl estradiol	2	17-hydroxy steroid; 3-hydroxy steroid; terminal acetylenic compound	xenoestrogen	1987	1988	36.5	low	0	2	0	0	0	0
9,10-dimethyl-1,2-benzanthracene	1	ortho-fused polycyclic arene; tetraphenes	carcinogenic agent	1978	1978	46.0	low	0	1	0	0	0	0
apomorphine	1	aporphine alkaloid	alpha-adrenergic drug; antidyskinesia agent; antiparkinson drug; dopamine agonist; emetic; serotonergic drug	1985	1985	39.0	low	0	1	0	0	0	0
bromodeoxyuridine	2	pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent	1977	1992	39.5	low	0	1	1	0	0	0
galactose	19	D-galactose; galactopyranose	Escherichia coli metabolite; mouse metabolite	1964	2008	33.2	low	0	6	11	2	0	0
phenylethyl alcohol	1	benzenes; primary alcohol	Aspergillus metabolite; fragrance; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite	2014	2014	10.0	low	0	0	0	0	1	0
tyrosine	6	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical	1986	2020	22.8	low	0	1	1	3	1	0
lactose	14	lactose		1981	2018	21.0	low	0	2	4	5	3	0
methionine	1	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical	1992	1992	32.0	low	0	0	1	0	0	0
1,2-dipalmitoylphosphatidylcholine	5			1995	2016	19.2	low	0	0	1	3	1	0
cycloheximide	1	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor	1976	1976	48.0	low	0	1	0	0	0	0
egtazic acid	1	diether; tertiary amino compound; tetracarboxylic acid	chelator	1994	1994	30.0	low	0	0	1	0	0	0
chloroform	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant	1999	1999	25.0	low	0	0	1	0	0	0
mannitol	2	mannitol	allergen; antiglaucoma drug; compatible osmolytes; Escherichia coli metabolite; food anticaking agent; food bulking agent; food humectant; food stabiliser; food thickening agent; hapten; metabolite; osmotic diuretic; sweetening agent	2008	2017	11.5	low	2	0	0	1	1	0
histidine	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	2014	2014	10.0	low	0	0	0	0	1	0
n-pentanol	1	pentanol; short-chain primary fatty alcohol	human metabolite; plant metabolite	1996	1996	28.0	low	0	0	1	0	0	0
tryptophan	1	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite	1999	1999	25.0	low	0	0	1	0	0	0
trichloroacetic acid	1	monocarboxylic acid; organochlorine compound	carcinogenic agent; metabolite; mouse metabolite	2009	2009	15.0	low	0	0	0	1	0	0
taurocholic acid	1	amino sulfonic acid; bile acid taurine conjugate	human metabolite	1982	1982	42.0	low	0	1	0	0	0	0
methylprednisolone	2	6-methylprednisolone; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antiemetic; environmental contaminant; neuroprotective agent; xenobiotic	2015	2019	7.0	low	1	0	0	0	2	0
xanthenes	1	xanthene		1994	1994	30.0	low	0	0	1	0	0	0
4-bromophenacyl bromide	1			1984	1984	40.0	low	0	1	0	0	0	0
uridine diphosphate glucose	1	UDP-D-glucose	fundamental metabolite	1978	1978	46.0	low	0	1	0	0	0	0
perylene	1	ortho- and peri-fused polycyclic arene; perylenes		1999	1999	25.0	low	0	0	1	0	0	0
quinazolines	3	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinazolines		1997	2008	20.0	low	0	0	1	2	0	0
cyclopentane	4	cycloalkane; cyclopentanes; volatile organic compound	non-polar solvent	1993	1995	30.2	low	0	0	4	0	0	0
isoxazoles	1	isoxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene		1996	1996	28.0	low	0	0	1	0	0	0
nitroblue tetrazolium	1	organic cation		1985	1985	39.0	low	0	1	0	0	0	0
triphenyltetrazolium	1	organic cation		2005	2005	19.0	low	0	0	0	1	0	0
hydrazine	1	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor	1984	1984	40.0	low	0	1	0	0	0	0
evans blue	1	organic sodium salt	fluorochrome; histological dye; sodium channel blocker; teratogenic agent	2011	2011	13.0	low	0	0	0	0	1	0
diazomethane	1	diazo compound	alkylating agent; antineoplastic agent; carcinogenic agent; poison	2005	2005	19.0	low	0	0	0	1	0	0
methochlorpromazine	1			1989	1989	35.0	low	0	1	0	0	0	0
orcinol	1	5-alkylresorcinol; dihydroxytoluene	Aspergillus metabolite	1997	1997	27.0	low	0	0	1	0	0	0
alpha-aminopyridine	2			2009	2010	14.5	low	0	0	0	2	0	0
cellobiose	1	cellobiose	epitope	2003	2003	21.0	low	0	0	0	1	0	0
malondialdehyde	1	dialdehyde	biomarker	2019	2019	5.0	low	0	0	0	0	1	0
cytidine diphosphate choline	2	nucleotide-(amino alcohol)s; phosphocholines	human metabolite; mouse metabolite; neuroprotective agent; psychotropic drug; Saccharomyces cerevisiae metabolite	1981	2002	32.5	low	0	1	0	1	0	0
potassium hydroxide	1	alkali metal hydroxide		2001	2001	23.0	low	0	0	0	1	0	0
dodecyldimethylamine oxide	1	tertiary amine oxide	detergent; plant metabolite	1990	1990	34.0	low	0	0	1	0	0	0
tricosanoic acid	1	straight-chain saturated fatty acid; very long-chain fatty acid	Daphnia magna metabolite; human metabolite; plant metabolite	2004	2004	20.0	low	0	0	0	1	0	0
fucose	4	fucopyranose; L-fucose	Escherichia coli metabolite; mouse metabolite	1977	2017	32.2	low	0	2	1	0	1	0
uridine diphosphate galactose	2	UDP-D-galactose	mouse metabolite	1979	1996	36.5	low	0	1	1	0	0	0
fluorescein-5-isothiocyanate	1	fluorescein isothiocyanate		1984	1984	40.0	low	0	1	0	0	0	0
mannose	3	D-aldohexose; D-mannose; mannopyranose	metabolite	1977	2017	27.7	low	0	1	1	0	1	0
manganese	3	elemental manganese; manganese group element atom	Escherichia coli metabolite; micronutrient	1982	1995	33.7	low	0	1	2	0	0	0
technetium	1	manganese group element atom		2006	2006	18.0	low	1	0	0	1	0	0
gold	4	copper group element atom; elemental gold		2013	2018	8.8	low	0	0	0	0	4	0
aluminum chloride	1	aluminium coordination entity	Lewis acid	1993	1993	31.0	low	0	0	1	0	0	0
cupric chloride	1	copper molecular entity; inorganic chloride	EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor	1993	1993	31.0	low	0	0	1	0	0	0
acetylglucosamine	5	N-acetyl-D-glucosamine	epitope	1977	2011	24.6	low	0	1	1	2	1	0
ferric chloride	1	iron coordination entity	astringent; Lewis acid	1993	1993	31.0	low	0	0	1	0	0	0
fluorine	1	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound	2004	2004	20.0	low	0	0	0	1	0	0
deuterium oxide	1	deuterated compound; water	NMR solvent	1996	1996	28.0	low	0	0	1	0	0	0
galactose	1			1978	1978	46.0	low	0	1	0	0	0	0
aluminum sulfate	2	aluminium sulfate		2014	2015	9.5	low	1	0	0	0	2	0
tetradecanoylphorbol acetate	12	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator	1984	2008	32.0	low	0	6	4	2	0	0
1-deoxynojirimycin	1	2-(hydroxymethyl)piperidine-3,4,5-triol; piperidine alkaloid	anti-HIV agent; anti-obesity agent; bacterial metabolite; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; plant metabolite	2013	2013	11.0	low	0	0	0	0	1	0
phosphotyrosine	9	L-tyrosine derivative; non-proteinogenic L-alpha-amino acid; O(4)-phosphotyrosine	Escherichia coli metabolite; immunogen	1986	2015	19.9	low	0	1	2	3	3	0
phenyl acetate	2	benzenes; phenyl acetates		1989	1992	33.5	low	0	1	1	0	0	0
8-bromo cyclic adenosine monophosphate	1	3',5'-cyclic purine nucleotide; adenyl ribonucleotide; organobromine compound	antidepressant; protein kinase agonist	1986	1986	38.0	low	0	1	0	0	0	0
tridemorph	1	morpholines; tertiary amino compound	antifungal agrochemical	2002	2002	22.0	low	0	0	0	1	0	0
glutamic acid	2	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical	2006	2007	17.5	low	0	0	0	2	0	0
torpedo	1			1993	1993	31.0	low	0	0	1	0	0	0
azides	1	pseudohalide anion	mitochondrial respiratory-chain inhibitor	2000	2000	24.0	low	0	0	1	0	0	0
zidovudine	1	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor	1999	1999	25.0	low	0	0	1	0	0	0
acetylgalactosamine	1	N-acetyl-D-hexosamine; N-acetylgalactosamine	Escherichia coli metabolite; human metabolite; mouse metabolite	1983	1983	41.0	low	0	1	0	0	0	0
etoposide	2	beta-D-glucoside; furonaphthodioxole; organic heterotetracyclic compound	antineoplastic agent; DNA synthesis inhibitor	2006	2007	17.5	low	0	0	0	2	0	0
n-(2-hydroxypropyl)methacrylamide	1			2008	2008	16.0	low	0	0	0	1	0	0
colforsin	1	acetate ester; cyclic ketone; labdane diterpenoid; organic heterotricyclic compound; tertiary alpha-hydroxy ketone; triol	adenylate cyclase agonist; anti-HIV agent; antihypertensive agent; plant metabolite; platelet aggregation inhibitor; protein kinase A agonist	1992	1992	32.0	low	0	0	1	0	0	0
miglustat	1	piperidines; tertiary amino compound	anti-HIV agent; EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor	2013	2013	11.0	low	0	0	0	0	1	0
fura-2	2			1992	1994	31.0	low	0	0	2	0	0	0
trichloroacetamide	1			2009	2009	15.0	low	0	0	0	1	0	0
octyl glucoside	1	beta-D-glucoside	plant metabolite	1981	1981	43.0	low	0	1	0	0	0	0
glucose, (beta-d)-isomer	1	D-glucopyranose	epitope; mouse metabolite	1981	1981	43.0	low	0	1	0	0	0	0
oseltamivir	1	acetamides; amino acid ester; cyclohexenecarboxylate ester; primary amino compound	antiviral drug; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; environmental contaminant; prodrug; xenobiotic	2020	2020	4.0	low	0	0	0	0	1	0
cholesteryl sulfate	1	steroid sulfate	human metabolite	1997	1997	27.0	low	0	0	1	0	0	0
25-hydroxycholesterol	1	25-hydroxy steroid; oxysterol	human metabolite	1994	1994	30.0	low	0	0	1	0	0	0
metaperiodate	1	iodine oxoacid		1995	1995	29.0	low	0	0	1	0	0	0
2-deoxy-2,3-dehydro-n-acetylneuraminic acid	2	N-acetylneuraminic acids		1989	2008	25.5	low	0	1	0	1	0	0
4-o-methyl-12-o-tetradecanoylphorbol 13-acetate	1			1984	1984	40.0	low	0	1	0	0	0	0
methylumbelliferyl-beta-d-xyloside	1			1993	1993	31.0	low	0	0	1	0	0	0
methyl beta-galactoside	1	beta-D-galactoside; methyl D-galactoside; monosaccharide derivative		1992	1992	32.0	low	0	0	1	0	0	0
fluo-3	1	xanthene dye	fluorochrome	1994	1994	30.0	low	0	0	1	0	0	0
parinaric acid	1	octadecatetraenoic acid		1993	1993	31.0	low	0	0	1	0	0	0
deoxyglucose	2			1978	2002	34.0	low	0	1	0	1	0	0
1-phenyl-2-decanoylamino-3-morpholino-1-propanol	12			1989	2016	20.2	low	0	1	2	6	3	0
caprylates	1	fatty acid anion 8:0; straight-chain saturated fatty acid anion	human metabolite; Saccharomyces cerevisiae metabolite	2014	2014	10.0	low	0	0	0	0	1	0
4-o-alpha-d-galactopyranosyl-d-galactose	1	O-acyl carbohydrate		1995	1995	29.0	low	0	0	1	0	0	0
methyl lactoside	1	disaccharide derivative; methyl glycoside		1992	1992	32.0	low	0	0	1	0	0	0
phytosphingosine	1	amino alcohol; sphingoid; triol	mouse metabolite; Saccharomyces cerevisiae metabolite	2018	2018	6.0	low	0	0	0	0	1	0
chapso	1			1993	1993	31.0	low	0	0	1	0	0	0
carbene	1	carbene; methanediyl		2005	2005	19.0	low	0	0	0	1	0	0
gefitinib	1	aromatic ether; monochlorobenzenes; monofluorobenzenes; morpholines; quinazolines; secondary amino compound; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist	2007	2007	17.0	low	0	0	0	1	0	0
3-deoxyglycero-galacto-nonulosonic acid	1	L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo		1994	1994	30.0	low	0	0	1	0	0	0
angiotensin ii, des-asp(1)-des-arg(2)-ile(5)-	1	organic molecular entity		2014	2014	10.0	low	0	0	0	0	1	0
n-acetylneuraminoyllactose	6			1981	2012	25.0	low	0	2	1	2	1	0
9-o-acetyl-n-acetylneuraminic acid	3	N-acetyl-O-acetylneuraminic acid		1996	2020	18.7	low	0	0	2	0	1	0
glycerophosphoinositol 4,5-bisphosphate	2			2016	2021	5.5	low	0	0	0	0	1	1
n-acetylneuraminosyl(alpha2-6)lactosamine	1	amino trisaccharide; glucosamine oligosaccharide	epitope	1990	1990	34.0	low	0	0	1	0	0	0
neuramin lactitol	2			1992	1996	30.0	high	0	0	2	0	0	0
phorbols	2	diterpene; terpenoid fundamental parent		1986	1986	38.0	low	0	2	0	0	0	0
2-deoxy-lyxo-hexose	1			1993	1993	31.0	low	0	0	1	0	0	0
uridine diphosphate galactosamine	1	UDP-amino sugar		2000	2000	24.0	medium	0	0	1	0	0	0
udp-glucosamine	1	UDP-amino sugar		2000	2000	24.0	low	0	0	1	0	0	0
biotin	4	biotins; vitamin B7	coenzyme; cofactor; Escherichia coli metabolite; fundamental metabolite; human metabolite; mouse metabolite; nutraceutical; prosthetic group; Saccharomyces cerevisiae metabolite	1989	2010	27.8	low	0	1	2	1	0	0
angiotensin ii	1	amino acid zwitterion; angiotensin II	human metabolite	2014	2014	10.0	low	0	0	0	0	1	0
erlotinib hydrochloride	1	hydrochloride; terminal acetylenic compound	antineoplastic agent; protein kinase inhibitor	2023	2023	1.0	low	0	0	0	0	0	1
cholic acid	1	12alpha-hydroxy steroid; 3alpha-hydroxy steroid; 7alpha-hydroxy steroid; bile acid; C24-steroid; trihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	1989	1989	35.0	low	0	1	0	0	0	0
deoxycholic acid	1	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human blood serum metabolite	1981	1981	43.0	low	0	1	0	0	0	0
wortmannin	1	acetate ester; cyclic ketone; delta-lactone; organic heteropentacyclic compound	anticoronaviral agent; antineoplastic agent; autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector; Penicillium metabolite; radiosensitizing agent	2007	2007	17.0	low	0	0	0	1	0	0
dihydropyridines	1			1994	1994	30.0	low	0	0	1	0	0	0
n-acetylneuraminic acid	60	N-acetylneuraminic acids	antioxidant; bacterial metabolite; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; human metabolite; mouse metabolite	1984	2023	22.5	low	1	8	24	17	8	3
glucosamine	5	D-glucosamine	Escherichia coli metabolite; geroprotector; mouse metabolite	1977	2000	35.6	low	0	2	3	0	0	0
elastin	1	oligopeptide		2010	2010	14.0	low	0	0	0	1	0	0
n-acetyllactosamine	1	beta-D-Galp-(1->4)-D-GlcpNAc		1997	1997	27.0	low	0	0	1	0	0	0
puromycin	1	puromycins	antiinfective agent; antimicrobial agent; antineoplastic agent; EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor; EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor; nucleoside antibiotic; protein synthesis inhibitor	1976	1976	48.0	low	0	1	0	0	0	0
n-glycolylneuraminic acid	13	N-acylneuraminic acid		1984	2013	25.7	low	0	4	4	4	1	0
mannosamine	1	D-mannosamine		2006	2006	18.0	low	0	0	0	1	0	0
monensin	1	cyclic hemiketal; monocarboxylic acid; polyether antibiotic; spiroketal	antifungal agent; coccidiostat; ionophore	1996	1996	28.0	low	0	0	1	0	0	0
naringin	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; neohesperidoside	anti-inflammatory agent; antineoplastic agent; metabolite	2016	2016	8.0	low	0	0	0	0	1	0
betadex	5	cyclodextrin		2004	2007	18.8	low	0	0	0	5	0	0
tretinoin	2	retinoic acid; vitamin A	anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule	1978	2007	31.5	low	0	1	0	1	0	0
arachidonic acid	3	icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid	Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite	1988	1994	32.7	low	0	1	2	0	0	0
retinol	1	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite	1978	1978	46.0	low	0	1	0	0	0	0
oleic acid	1	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent	1991	1991	33.0	low	0	0	1	0	0	0
tacrolimus	1	macrolide lactam	bacterial metabolite; immunosuppressive agent	1995	1995	29.0	low	0	0	1	0	0	0
cytidine monophosphate n-acetylneuraminic acid	2	CMP-N-acyl-beta-neuraminic acid	mouse metabolite	1977	1989	41.0	low	0	2	0	0	0	0
h 89	1	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide		1999	1999	25.0	low	0	0	1	0	0	0
enkephalin, leucine	1	pentapeptide; peptide zwitterion	analgesic; delta-opioid receptor agonist; human metabolite; mu-opioid receptor agonist; neurotransmitter; rat metabolite	1984	1984	40.0	low	0	1	0	0	0	0
glycosides	7			1993	2014	23.0	low	0	0	4	2	1	0
isomethyleugenol	6	isomethyleugenol		1977	2009	28.8	low	0	2	1	3	0	0
n-acetylneuraminoyllactose	1			2009	2009	15.0	low	0	0	0	1	0	0
arginine vasopressin	1	vasopressin	cardiovascular drug; hematologic agent; mitogen	1986	1986	38.0	low	0	1	0	0	0	0
hypocrellin b	1			1999	1999	25.0	low	0	0	1	0	0	0
fumonisin b1	3	diester; fumonisin; primary amino compound; triol	carcinogenic agent; metabolite	1997	2013	19.0	low	0	0	1	1	1	0
tamoxifen	1	stilbenoid; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; bone density conservation agent; EC 1.2.3.1 (aldehyde oxidase) inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; estrogen antagonist; estrogen receptor antagonist; estrogen receptor modulator	2002	2002	22.0	low	0	0	0	1	0	0
sodium taurodeoxycholate	1	bile acid taurine conjugate	human metabolite	1981	1981	43.0	low	0	1	0	0	0	0
krn 7000	2	glycophytoceramide; N-acyl-beta-D-galactosylphytosphingosine	allergen; antigen; antineoplastic agent; epitope; immunological adjuvant	2008	2021	9.5	low	0	0	0	1	0	1
rtki cpd	2			1997	2008	21.5	low	0	0	1	1	0	0
safingol	2	amino alcohol		1989	1997	31.0	low	0	1	1	0	0	0
n-(2,4,6-trinitrophenyl-6-n-aminocaproyl)-1,2-dipalmitoylphosphatidylethanolamine	1			1983	1983	41.0	medium	0	1	0	0	0	0
phosphothreonine	1	L-threonine derivative; non-proteinogenic L-alpha-amino acid; O-phosphoamino acid	Escherichia coli metabolite	1994	1994	30.0	low	0	0	1	0	0	0
ovalbumin	1			2006	2006	18.0	low	0	0	0	1	0	0
chloramine-t	1	organic sodium salt	allergen; antifouling biocide; disinfectant	2005	2005	19.0	low	0	0	0	1	0	0
myelin basic protein	1			1994	1994	30.0	low	0	0	1	0	0	0
sphingosine	15	sphing-4-enine	human metabolite; mouse metabolite	1977	2021	25.5	low	0	3	7	3	1	1
dinoprostone	2	prostaglandins E	human metabolite; mouse metabolite; oxytocic	1993	2003	26.0	low	0	0	1	1	0	0
arachidonyltrifluoromethane	1	fatty acid derivative; ketone; olefinic compound; organofluorine compound	EC 3.1.1.4 (phospholipase A2) inhibitor	1998	1998	26.0	low	0	0	1	0	0	0
calcitriol	2	D3 vitamins; hydroxycalciol; triol	antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical	1986	1989	36.5	low	0	2	0	0	0	0
psychosine	1	glycosylsphingoid	human metabolite	1996	1996	28.0	low	0	0	1	0	0	0
hymecromone	1	hydroxycoumarin	antineoplastic agent; hyaluronic acid synthesis inhibitor	1993	1993	31.0	low	0	0	1	0	0	0
alprostadil	2	prostaglandins E	anticoagulant; human metabolite; platelet aggregation inhibitor; vasodilator agent	1989	1992	33.5	low	0	1	1	0	0	0
6-ketoprostaglandin f1 alpha	1	prostaglandins Falpha	human metabolite; mouse metabolite	1993	1993	31.0	low	0	0	1	0	0	0
genistein	1	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor	1995	1995	29.0	low	0	0	1	0	0	0
caffeic acid phenethyl ester	1	alkyl caffeate ester	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiviral agent; immunomodulator; metabolite; neuroprotective agent	2014	2014	10.0	low	0	0	0	0	1	0
thromboxane b2	1	thromboxanes B	human metabolite; mouse metabolite	1993	1993	31.0	low	0	0	1	0	0	0
sphingosine 1-phosphate	1	sphingoid 1-phosphate	mouse metabolite; signalling molecule; sphingosine-1-phosphate receptor agonist; T-cell proliferation inhibitor; vasodilator agent	2010	2010	14.0	low	0	0	0	1	0	0
brefeldin a	7	macrolide antibiotic	Penicillium metabolite	1993	2002	27.1	low	0	0	5	2	0	0
fenretinide	1	monocarboxylic acid amide; retinoid	antineoplastic agent; antioxidant	2002	2002	22.0	low	0	0	0	1	0	0
morphine	1	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic	1987	1987	37.0	low	0	1	0	0	0	0
herbimycin	2	1,4-benzoquinones; lactam; macrocycle	antimicrobial agent; apoptosis inducer; herbicide; Hsp90 inhibitor; tyrosine kinase inhibitor	1995	1999	27.0	low	0	0	2	0	0	0
lysophosphatidylcholines	1	1-O-acyl-sn-glycero-3-phosphocholine		1990	1990	34.0	low	0	0	1	0	0	0
cytochalasin b	1	cytochalasin; lactam; lactone; organic heterotricyclic compound	actin polymerisation inhibitor; metabolite; mycotoxin; platelet aggregation inhibitor	1997	1997	27.0	low	0	0	1	0	0	0
1,2-oleoylphosphatidylcholine	1	phosphatidylcholine(1+)		2003	2003	21.0	low	0	0	0	1	0	0
aluminum	1	boron group element atom; elemental aluminium; metal atom		1993	1993	31.0	low	0	0	1	0	0	0
dimyristoylphosphatidylcholine	4	1,2-diacyl-sn-glycero-3-phosphocholine; phosphatidylcholine 28:0; tetradecanoate ester	antigen; mouse metabolite	1993	2011	25.2	low	0	0	3	0	1	0
cysteine	1	cysteinium	fundamental metabolite	2021	2021	3.0	low	0	0	0	0	0	1
phosphorus	1	monoatomic phosphorus; nonmetal atom; pnictogen	macronutrient	2001	2001	23.0	low	0	0	0	1	0	0
dizocilpine maleate	1	maleate salt; tetracyclic antidepressant	anaesthetic; anticonvulsant; neuroprotective agent; nicotinic antagonist; NMDA receptor antagonist	1993	1993	31.0	low	0	0	1	0	0	0
1,2-dioleoylphosphatidylserine	1	phosphatidylserine(18:1/18:1)	mouse metabolite	2016	2016	8.0	low	0	0	0	0	1	0
ganglioside gm3 lactone	13			1985	2018	24.8	high	0	3	5	3	2	0
cdw17 antigen	26			1987	2012	25.4	medium	0	4	13	6	3	0
ganglioside, gd1b	20			1982	2019	25.2	low	0	4	7	6	3	0
trisialoganglioside gt1	36			1982	2009	29.5	medium	0	12	14	10	0	0
ganglioside, gd2	13			1988	2014	26.2	low	0	2	7	3	1	0
asialo gm1 ganglioside	4			1995	2007	22.2	low	0	0	2	2	0	0
sialosylparagloboside	3			1982	1994	35.3	high	0	1	2	0	0	0
i(3)so3-galactosylceramide	10	galactosylceramide sulfate; N-acyl-beta-D-galactosylsphingosine		1979	2021	28.0	low	0	3	5	1	0	1
beta-escin	1			2004	2004	20.0	low	0	0	0	1	0	0
sq-23377	1	cyclic ether; enol; polyunsaturated fatty acid; very long-chain fatty acid	calcium ionophore; metabolite	2000	2000	24.0	low	0	0	1	0	0	0
enkephalin, leucine-2-alanine	1			1984	1984	40.0	low	0	1	0	0	0	0
dexniguldipine	1	diarylmethane		1994	1994	30.0	low	0	0	1	0	0	0
staurosporine	1	ammonium ion derivative		1999	1999	25.0	low	0	0	1	0	0	0
lipid a	3	dodecanoate ester; lipid A; tetradecanoate ester	Escherichia coli metabolite	1994	2012	18.7	low	0	0	1	1	1	0
g(m2) ganglioside	93	N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine; sialotriaosylceramide	antigen	1976	2023	26.0	medium	0	24	31	23	14	1
tetramethylrhodamine	1	xanthene dye		2007	2007	17.0	low	0	0	0	1	0	0
g(m1) ganglioside	144	alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine; sialotetraosylceramide		1976	2023	27.1	medium	0	42	49	38	13	2
alpha-synuclein	6			2007	2023	10.3	low	0	0	0	2	3	1
tamiphosphor	1			2020	2020	4.0	low	0	0	0	0	1	0
ki 8751	1	aromatic ether		2019	2019	5.0	low	0	0	0	0	1	0
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc	3	amino tetrasaccharide; glucosamine oligosaccharide	epitope	2000	2002	23.0	low	0	0	1	2	0	0
n-acetylmannosamine	1			1988	1988	36.0	low	0	1	0	0	0	0
calcimycin	1	benzoxazole		1976	1976	48.0	low	0	1	0	0	0	0
pituitrin	1			1988	1988	36.0	low	0	1	0	0	0	0
melitten	1			2020	2020	4.0	low	0	0	0	0	1	0
glucagon	1	peptide hormone		1990	1990	34.0	low	0	0	1	0	0	0
prosaptide	1			1996	1996	28.0	low	0	0	1	0	0	0
endothelin-1	1			2001	2001	23.0	low	0	0	0	1	0	0
phosphatidylcholines	6	1,2-diacyl-sn-glycero-3-phosphocholine		1990	2020	19.7	low	0	0	2	2	2	0
calpain	1			2007	2007	17.0	low	0	0	0	1	0	0
lucifer yellow	1	organic lithium salt	fluorochrome	1984	1984	40.0	low	0	1	0	0	0	0
eliglustat	1	benzodioxine; carboxamide; N-alkylpyrrolidine; secondary alcohol	EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor	2014	2014	10.0	low	1	0	0	0	1	0
bucladesine	3	3',5'-cyclic purine nucleotide		1977	1992	38.0	low	0	2	1	0	0	0
ganglioside, gd1a	51			1981	2015	29.0	medium	0	18	16	15	2	0
glycolipids	67			1977	2023	28.5	low	0	22	23	13	8	1
piperidines	1			2014	2014	10.0	low	0	0	0	0	1	0
uridine diphosphate n-acetylgalactosamine	3	nucleotide-sugar oxoanion	human metabolite	1981	2000	36.3	low	0	2	1	0	0	0
diphthamide	1	quaternary ammonium ion		2014	2014	10.0	low	0	0	0	0	1	0
heparitin sulfate	3			1977	2021	19.3	low	0	1	0	0	1	1
epidermal growth factor	24			1984	2021	23.4	low	0	4	7	9	3	1
transforming growth factor beta	3			1994	2020	17.7	low	0	0	1	1	1	0
okadaic acid	1	ketal		1992	1992	32.0	low	0	0	1	0	0	0
1,2-dipalmitoyl-sn-glycero-3-ethylphosphocholine	1			2016	2016	8.0	low	0	0	0	0	1	0
globotriaosylceramide	4			1988	1998	30.0	low	0	1	3	0	0	0
bgp 15	1			2014	2014	10.0	low	0	0	0	0	1	0
ganglioside gm1alpha	1			2014	2014	10.0	low	0	0	0	0	1	0
lewis x antigen	4			1994	2000	26.2	low	0	0	4	0	0	0
humulin s	1			2023	2023	1.0	low	0	0	0	0	0	1
cyclosporine	2			1994	1999	27.5	low	0	0	2	0	0	0
o-acetyl sialic acid	1			2020	2020	4.0	medium	0	0	0	0	1	0
amyloid beta-peptides	1			2010	2010	14.0	low	0	0	0	1	0	0
chondroitin sulfates	1			1977	1977	47.0	low	0	1	0	0	0	0
ganglio-n-triaosylceramide	3			1994	2007	25.3	low	0	0	2	1	0	0
fucosyl gm1 ganglioside	2			1997	2018	16.5	low	0	0	1	0	1	0
guanosine diphosphate	1	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	1998	1998	26.0	low	0	0	1	0	0	0
guanosine triphosphate	2	guanosine 5'-phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	1990	1998	30.0	low	0	0	2	0	0	0
guanosine 5'-o-(3-thiotriphosphate)	1	nucleoside triphosphate analogue		1990	1990	34.0	low	0	0	1	0	0	0
n-glycolylneuraminyllactosylceramide	38	sialotriaosylceramide	tumour antigen	1985	2019	17.8	high	4	2	9	10	17	0
concanavalin a	2			1986	1991	35.5	low	0	1	1	0	0	0
ganglioside, gm4	10			1981	2001	34.9	high	0	6	3	1	0	0
gq1b ganglioside	6			1988	2019	23.8	low	0	1	2	2	1	0
leptin	1			2018	2018	6.0	low	0	0	0	0	1	0
filipin	1			2007	2007	17.0	low	0	0	0	1	0	0

Condition	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
(pPNET) Peripheral Primitive Neuroectodermal Tumors	1	1994	1994	30.0	low	0	0	1	0	0	0
2019 Novel Coronavirus Disease	2	2020	2023	2.5	low	0	0	0	0	1	1
Abnormal Deep Tendon Reflex	1	2000	2000	24.0	low	0	0	1	0	0	0
Abortion, Habitual	1	1995	1995	29.0	low	0	0	1	0	0	0
Abortion, Recurrent	1	1995	1995	29.0	low	0	0	1	0	0	0
Absence Seizure	2	2001	2022	12.5	low	0	0	0	1	0	1
Acetyl-CoA:alpha-Glucosaminide N-Acetyltransferase Deficiency	9	1980	2021	15.0	low	0	1	0	2	5	1
Ache	1	2016	2016	8.0	low	0	0	0	0	1	0
Acid beta-Glucosidase Deficiency	5	1984	2014	19.2	low	1	1	0	3	1	0
Acquired Immune Deficiency Syndrome	2	1993	1994	30.5	low	0	0	2	0	0	0
Acquired Immunodeficiency Syndrome	2	1993	1994	30.5	low	0	0	2	0	0	0
Acrania	1	1991	1991	33.0	low	0	0	1	0	0	0
Actinobacillus Infections	1	2005	2005	19.0	low	0	0	0	1	0	0
Action Tremor	1	2000	2000	24.0	low	0	0	1	0	0	0
Acute Autoimmune Neuropathy	3	2001	2019	11.3	low	0	0	0	1	2	0
Acute Confusional Senile Dementia	4	2009	2022	10.0	low	0	0	0	2	1	1
Acute Disease	2	2006	2015	13.5	low	1	0	0	1	1	0
Acute Myelogenous Leukemia	5	1985	1988	38.0	low	0	5	0	0	0	0
Acute Promyelocytic Leukemia	2	1989	1993	33.0	low	0	1	1	0	0	0
Acute Relapsing Multiple Sclerosis	2	2001	2003	22.0	low	0	0	0	2	0	0
ADDH	1	2011	2011	13.0	low	0	0	0	0	1	0
Adenocarcinoma	11	1979	2011	24.6	low	0	1	4	4	2	0
Adenocarcinoma Of Kidney	2	2000	2004	22.0	low	0	0	1	1	0	0
Adenocarcinoma of Lung	1	2011	2011	13.0	low	0	0	0	0	1	0
Adenocarcinoma, Basal Cell	11	1979	2011	24.6	low	0	1	4	4	2	0
Adjuvant Arthritis	1	2012	2012	12.0	low	0	0	0	0	1	0
Adrenoleukodystrophy, Autosomal Neonatal Form	1	2001	2001	23.0	low	0	0	0	1	0	0
Adult GM1 Gangliosidosis	1	1992	1992	32.0	low	0	0	1	0	0	0
Adult Neuronal Ceroid Lipofuscinosis	2	2014	2018	8.0	low	0	0	0	0	2	0
Adult Refsum Disease	1	2001	2001	23.0	low	0	0	0	1	0	0
African Lymphoma	1	1995	1995	29.0	low	0	0	1	0	0	0
Aging	10	1978	2021	23.5	low	0	2	3	3	1	1
Alcohol Abuse	1	1988	1988	36.0	low	0	1	0	0	0	0
Alcoholism	1	1988	1988	36.0	low	0	1	0	0	0	0
Alloxan Diabetes	4	2003	2018	11.8	low	0	0	0	1	3	0
alpha-L-Iduronidase Deficiency	1	1980	1980	44.0	low	0	1	0	0	0	0
ALS - Amyotrophic Lateral Sclerosis	1	2015	2015	9.0	low	0	0	0	0	1	0
Alzheimer Disease	4	2009	2022	10.0	low	0	0	0	2	1	1
Amaurosis	1	2004	2004	20.0	low	0	0	0	1	0	0
Amaurotic Familial Idiocy	1	1983	1983	41.0	low	0	1	0	0	0	0
Amyloid Angiopathy, Cerebral	1	2009	2009	15.0	low	0	0	0	1	0	0
Amyloid Deposits	1	2022	2022	2.0	low	0	0	0	0	0	1
Amyotrophic Lateral Sclerosis	1	2015	2015	9.0	low	0	0	0	0	1	0
Anaplastic Astrocytoma	4	1980	1994	36.2	low	0	3	1	0	0	0
Anemia, Hemolytic	1	2001	2001	23.0	low	0	0	0	1	0	0
Anemia, Hemolytic, Acquired	1	2001	2001	23.0	low	0	0	0	1	0	0
Angioblastic Meningioma	3	1989	2021	24.0	low	0	1	1	0	0	1
Angiogenesis, Pathologic	5	1992	2021	18.4	low	0	0	2	2	0	1
Animal Mammary Carcinoma	1	2016	2016	8.0	low	0	0	0	0	1	0
Anochlesia	1	2000	2000	24.0	low	0	0	1	0	0	0
Anxiety	1	2014	2014	10.0	low	0	0	0	0	1	0
Aortic Diseases	3	1999	2009	21.0	low	0	0	1	2	0	0
Arachnoidal Cerebellar Sarcoma, Circumscribed	1	1997	1997	27.0	low	0	0	1	0	0	0
Argentaffinoma	1	2007	2007	17.0	low	0	0	0	1	0	0
ARSA Deficiency	1	1980	1980	44.0	low	0	1	0	0	0	0
ARSB Deficiency	1	1980	1980	44.0	low	0	1	0	0	0	0
Arteriosclerosis	10	1977	2001	30.6	low	0	3	6	1	0	0
Arteriosclerosis, Coronary	1	1999	1999	25.0	low	0	0	1	0	0	0
Arthritis, Degenerative	3	1995	2017	16.0	low	0	0	1	0	2	0
Arthritis, Rheumatoid	1	2012	2012	12.0	low	0	0	0	0	1	0
Ascites	1	1984	1984	40.0	low	0	1	0	0	0	0
Astheno Teratozoospermia	1	2021	2021	3.0	low	0	0	0	0	0	1
Astrocytoma	4	1980	1994	36.2	low	0	3	1	0	0	0
Astrocytoma, Grade IV	3	1988	2001	29.7	low	0	1	1	1	0	0
Asymmetric Diabetic Proximal Motor Neuropathy	1	1999	1999	25.0	low	0	0	1	0	0	0
Ataxia	1	2000	2000	24.0	low	0	0	1	0	0	0
Atherogenesis	3	2009	2021	7.7	low	0	0	0	1	1	1
Atheroma	2	2019	2021	4.0	low	0	0	0	0	1	1
Atherosclerosis	3	2009	2021	7.7	low	0	0	0	1	1	1
Atrial Fibrillation	1	2014	2014	10.0	low	0	0	0	0	1	0
Attention Deficit Disorder with Hyperactivity	1	2011	2011	13.0	low	0	0	0	0	1	0
Aura	4	2004	2016	11.8	low	0	0	0	1	3	0
Auricular Fibrillation	1	2014	2014	10.0	low	0	0	0	0	1	0
Autoimmune Diabetes	3	2005	2018	12.0	low	0	0	0	1	2	0
Autoimmune Disease	1	2010	2010	14.0	low	0	0	0	1	0	0
Autoimmune Diseases	1	2010	2010	14.0	low	0	0	0	1	0	0
B16 Melanoma	34	1987	2020	25.8	low	0	8	16	8	2	0
Basophilic Leukemia, Acute	1	2000	2000	24.0	low	0	0	1	0	0	0
Benign Cerebellar Neoplasms	1	1997	1997	27.0	low	0	0	1	0	0	0
Benign Meningeal Neoplasms	2	1989	1990	34.5	low	0	1	1	0	0	0
Benign Neoplasms	25	1980	2020	15.8	low	0	1	5	6	13	0
Benign Neoplasms, Brain	9	1979	2019	27.1	low	0	2	4	2	1	0
Berger Disease	1	1992	1992	32.0	low	0	0	1	0	0	0
Besnier-Boeck Disease	1	2010	2010	14.0	low	0	0	0	1	0	0
Birth Weight	1	2016	2016	8.0	low	0	0	0	0	1	0
Bladder Cancer	6	2001	2013	19.0	low	0	0	0	5	1	0
Blindness	1	2004	2004	20.0	low	0	0	0	1	0	0
Blood Pressure, High	1	1988	1988	36.0	low	0	1	0	0	0	0
Body Weight	3	2002	2016	15.3	low	0	0	0	2	1	0
Bovine Diseases	1	2003	2003	21.0	low	0	0	0	1	0	0
Bowel Diseases, Inflammatory	1	2014	2014	10.0	low	0	0	0	0	1	0
Brain Diseases	1	1980	1980	44.0	low	0	1	0	0	0	0
Brain Disorders	1	1980	1980	44.0	low	0	1	0	0	0	0
Brain Ischemia	2	2005	2015	14.0	low	0	0	0	1	1	0
Brain Neoplasms	9	1979	2019	27.1	low	0	2	4	2	1	0
Breast Cancer	16	1991	2023	21.1	low	4	0	7	5	3	1
Breast Neoplasms	16	1991	2023	21.1	low	4	0	7	5	3	1
Bronchial Neoplasms	1	2007	2007	17.0	low	0	0	0	1	0	0
Bulbar Palsy	3	2006	2018	12.7	low	0	0	0	2	1	0
Burkitt Lymphoma	1	1995	1995	29.0	low	0	0	1	0	0	0
Calcification, Pathologic	1	1994	1994	30.0	low	0	0	1	0	0	0
Calcinosis	1	1994	1994	30.0	low	0	0	1	0	0	0
Campylobacter Infection	1	2004	2004	20.0	low	0	0	0	1	0	0
Cancer of Colon	11	1983	2020	25.2	low	0	2	3	5	1	0
Cancer of Esophagus	1	1991	1991	33.0	low	0	0	1	0	0	0
Cancer of Eye	1	2008	2008	16.0	low	1	0	0	1	0	0
Cancer of Head	2	1989	2018	20.5	low	0	1	0	0	1	0
Cancer of Kidney	4	1983	2004	27.5	low	0	1	2	1	0	0
Cancer of Liver	6	1978	2013	32.3	low	0	2	3	0	1	0
Cancer of Lung	23	1979	2018	20.4	low	2	2	6	8	7	0
Cancer of Mouth	2	1986	2012	25.0	low	0	1	0	0	1	0
Cancer of Ovary	5	1986	2022	19.0	low	0	1	1	1	1	1
Cancer of Pancreas	2	1983	1991	37.0	low	0	1	1	0	0	0
Cancer of Rectum	1	1983	1983	41.0	low	0	1	0	0	0	0
Cancer of Skin	14	1988	2020	23.9	low	1	2	5	6	1	0
Cancer of Stomach	4	1991	2001	30.0	low	0	0	3	1	0	0
Cancer of the Retina	1	2015	2015	9.0	low	0	0	0	0	1	0
Cancer of the Thyroid	1	1990	1990	34.0	low	0	0	1	0	0	0
Cancer of the Uterus	1	1996	1996	28.0	low	0	0	1	0	0	0
Carbohydrate Metabolism, Inborn Error	1	1984	1984	40.0	low	0	1	0	0	0	0
Carbohydrate-Deficient Glycoprotein Syndrome	1	2019	2019	5.0	low	0	0	0	0	1	0
Carcinogenesis	1	2013	2013	11.0	low	0	0	0	0	1	0
Carcinoid Tumor	1	2007	2007	17.0	low	0	0	0	1	0	0
Carcinoma	3	1990	2019	20.3	low	0	0	1	1	1	0
Carcinoma, Anaplastic	3	1990	2019	20.3	low	0	0	1	1	1	0
Carcinoma, Basal Cell	2	1992	1992	32.0	low	0	0	2	0	0	0
Carcinoma, Basal Cell, Pigmented	2	1992	1992	32.0	low	0	0	2	0	0	0
Carcinoma, Ductal, Breast	1	2006	2006	18.0	low	1	0	0	1	0	0
Carcinoma, Epidermoid	10	1979	2007	28.4	low	0	3	4	3	0	0
Carcinoma, Hepatocellular	5	1978	2015	22.2	low	0	1	1	0	3	0
Carcinoma, Large Cell	1	2007	2007	17.0	low	0	0	0	1	0	0
Carcinoma, Lewis Lung	4	2006	2016	13.2	low	0	0	0	2	2	0
Carcinoma, Non-Small Cell Lung	12	1997	2018	13.0	low	1	0	1	4	7	0
Carcinoma, Non-Small-Cell Lung	12	1997	2018	13.0	low	1	0	1	4	7	0
Carcinoma, Oat Cell	2	1979	2007	31.0	low	1	1	0	1	0	0
Carcinoma, Papillary	1	1990	1990	34.0	low	0	0	1	0	0	0
Carcinoma, Renal Cell	2	2000	2004	22.0	low	0	0	1	1	0	0
Carcinoma, Small Cell	2	1979	2007	31.0	low	1	1	0	1	0	0
Carcinoma, Squamous Cell	10	1979	2007	28.4	low	0	3	4	3	0	0
Carcinoma, Transitional Cell	1	2002	2002	22.0	low	0	0	0	1	0	0
Cardiac Failure	1	2014	2014	10.0	low	0	0	0	0	1	0
Cardiometabolic Syndrome	3	2011	2015	10.7	low	0	0	0	0	3	0
Cataract	1	1982	1982	42.0	low	0	1	0	0	0	0
Cataract, Membranous	1	1982	1982	42.0	low	0	1	0	0	0	0
Cell Transformation, Neoplastic	9	1977	2005	33.2	low	0	5	0	4	0	0
Cell Transformation, Viral	1	1990	1990	34.0	low	0	0	1	0	0	0
Cerebral Amyloid Angiopathy	1	2009	2009	15.0	low	0	0	0	1	0	0
Cerebral Infarction, Middle Cerebral Artery	1	2005	2005	19.0	low	0	0	0	1	0	0
Cerebral Ischemia	2	2005	2015	14.0	low	0	0	0	1	1	0
Cerebro-Hepato-Renal Syndrome	1	2001	2001	23.0	low	0	0	0	1	0	0
Chancroid	1	2006	2006	18.0	low	0	0	0	1	0	0
Cherry Red Spot Myoclonus Syndrome	5	1980	1989	39.8	low	0	5	0	0	0	0
Child Development Deviations	1	2004	2004	20.0	low	0	0	0	1	0	0
Cholelithiasis	1	1991	1991	33.0	low	0	0	1	0	0	0
Choriocarcinoma	1	1996	1996	28.0	low	0	0	1	0	0	0
Chromosome Deletion	1	1990	1990	34.0	low	0	0	1	0	0	0
Chronic Progressive Multiple Sclerosis	1	2003	2003	21.0	low	0	0	0	1	0	0
Cirrhosis	1	2020	2020	4.0	low	0	0	0	0	1	0
Cirrhosis, Liver	1	1991	1991	33.0	low	0	0	1	0	0	0
Clinically Isolated CNS Demyelinating Syndrome	3	1994	2001	25.7	low	0	0	2	1	0	0
Colitis Gravis	2	2014	2015	9.5	low	0	0	0	0	2	0
Colitis, Granulomatous	2	2014	2015	9.5	low	0	0	0	0	2	0
Colitis, Ulcerative	2	2014	2015	9.5	low	0	0	0	0	2	0
Colonic Neoplasms	11	1983	2020	25.2	low	0	2	3	5	1	0
Colorectal Cancer	3	1999	2021	15.3	low	0	0	1	1	0	1
Colorectal Neoplasms	3	1999	2021	15.3	low	0	0	1	1	0	1
Condition, Preneoplastic	1	1978	1978	46.0	low	0	1	0	0	0	0
Congenital Disorders of Glycosylation	1	2019	2019	5.0	low	0	0	0	0	1	0
Corneal Diseases	1	2011	2011	13.0	low	0	0	0	0	1	0
Coronary Artery Disease	1	1999	1999	25.0	low	0	0	1	0	0	0
Coronavirus Infections	1	2020	2020	4.0	low	0	0	0	0	1	0
Cranial Nerve II Diseases	1	2019	2019	5.0	low	0	0	0	0	1	0
Crohn Disease	2	2014	2015	9.5	low	0	0	0	0	2	0
Cytomegalovirus	1	1992	1992	32.0	low	0	0	1	0	0	0
Deafness, Transitory	1	2011	2011	13.0	low	0	0	0	0	1	0
Deficiency, Vitamin D	1	2011	2011	13.0	low	0	0	0	0	1	0
Degenerative Disease, Nervous System, Hereditary	1	2021	2021	3.0	low	0	0	0	0	0	1
Degenerative Diseases, Central Nervous System	1	2016	2016	8.0	low	0	0	0	0	1	0
Dementia Praecox	1	1988	1988	36.0	low	0	1	0	0	0	0
Demyelinating Diseases	3	1994	2001	25.7	low	0	0	2	1	0	0
Dental Granuloma	1	2001	2001	23.0	low	0	0	0	1	0	0
Dermatoses	2	1989	2008	25.5	low	1	1	0	1	0	0
Developmental Disabilities	1	2004	2004	20.0	low	0	0	0	1	0	0
Diabetes Mellitus	2	2011	2014	11.5	low	0	0	0	0	2	0
Diabetes Mellitus, Adult-Onset	13	1999	2020	13.2	low	0	0	1	4	8	0
Diabetes Mellitus, Type 1	3	2005	2018	12.0	low	0	0	0	1	2	0
Diabetes Mellitus, Type 2	13	1999	2020	13.2	low	0	0	1	4	8	0
Diabetic Feet	1	2017	2017	7.0	low	0	0	0	0	1	0
Diabetic Foot	1	2017	2017	7.0	low	0	0	0	0	1	0
Diabetic Glomerulosclerosis	4	2003	2015	15.0	low	0	0	0	2	2	0
Diabetic Nephropathies	4	2003	2015	15.0	low	0	0	0	2	2	0
Diabetic Neuropathies	1	1999	1999	25.0	low	0	0	1	0	0	0
Diabetic Retinopathy	1	2005	2005	19.0	low	0	0	0	1	0	0
Diarrhea	2	2003	2011	17.0	low	0	0	0	1	1	0
Diffuse Parenchymal Lung Disease	1	2010	2010	14.0	low	0	0	0	1	0	0
Disease Exacerbation	8	1997	2016	17.8	low	0	0	3	2	3	0
Disease Models, Animal	30	2000	2022	12.0	low	0	0	1	10	17	2
Diseases, Metabolic	3	2010	2022	7.3	low	0	0	0	1	1	1
Dysembryoma	2	1981	2000	33.5	low	0	1	1	0	0	0
Dyskinesia, Drug-Induced	1	1989	1989	35.0	low	1	1	0	0	0	0
Dyskinesia, Medication-Induced	1	1989	1989	35.0	low	1	1	0	0	0	0
Dysplastic Nevus Syndrome, Hereditary	1	2020	2020	4.0	low	0	0	0	0	1	0
E coli Infections	2	1993	2003	26.0	low	0	0	1	1	0	0
Eccentro-Osteochondrodysplasia	1	1980	1980	44.0	low	0	1	0	0	0	0
EHS Tumor	2	1982	2011	27.5	low	0	1	0	0	1	0
Elevated Cholesterol	1	2018	2018	6.0	low	0	0	0	0	1	0
Epilepsy	4	2004	2016	11.8	low	0	0	0	1	3	0
ER-Negative PR-Negative HER2-Negative Breast Cancer	1	2019	2019	5.0	low	0	0	0	0	1	0
Escherichia coli Infections	2	1993	2003	26.0	low	0	0	1	1	0	0
Esophageal Neoplasms	1	1991	1991	33.0	low	0	0	1	0	0	0
Experimental Hepatoma	3	1979	1990	38.3	low	0	2	1	0	0	0
Experimental Leukemia	1	1989	1989	35.0	low	0	1	0	0	0	0
Experimental Mammary Neoplasms	6	1992	2021	22.3	low	0	0	3	2	0	1
Experimental Neoplasms	4	1977	2015	36.2	low	0	3	0	0	1	0
Extravascular Hemolysis	2	1985	1996	33.5	low	0	1	1	0	0	0
Eye Cancer, Retinoblastoma	2	1988	2015	22.5	low	0	1	0	0	1	0
Familial Waldenstrom's Macroglobulinaemia	1	1978	1978	46.0	low	0	1	0	0	0	0
Fibrosarcoma	1	1990	1990	34.0	low	0	0	1	0	0	0
Fibrosis	1	2020	2020	4.0	low	0	0	0	0	1	0
Fisher Syndrome	1	2019	2019	5.0	low	0	0	0	0	1	0
Fowl Paralysis	1	1982	1982	42.0	low	0	1	0	0	0	0
G(M2) Gangliosidoses	3	2007	2016	11.7	low	0	0	0	1	2	0
Gallstone Disease	1	1991	1991	33.0	low	0	0	1	0	0	0
Ganglioside Storage Diseases	5	1978	2001	38.2	low	0	4	0	1	0	0
Gangliosidoses	5	1978	2001	38.2	low	0	4	0	1	0	0
Gangliosidoses, GM2	3	2007	2016	11.7	low	0	0	0	1	2	0
Gangliosidosis, GM1	1	1992	1992	32.0	low	0	0	1	0	0	0
Gargoylism, Hunter Syndrome	1	2017	2017	7.0	low	0	0	0	0	1	0
Gastric Ulcer	1	2013	2013	11.0	low	0	0	0	0	1	0
Gaucher Disease	5	1984	2014	19.2	low	1	1	0	3	1	0
Gelineau Syndrome	1	2015	2015	9.0	low	0	0	0	0	1	0
Genetic Predisposition	1	2016	2016	8.0	low	0	0	0	0	1	0
Germinoblastoma	3	1991	2019	17.0	low	1	0	1	0	2	0
Glial Cell Tumors	12	1984	2005	29.8	low	0	4	5	3	0	0
Glioblastoma	3	1988	2001	29.7	low	0	1	1	1	0	0
Glioma	12	1984	2005	29.8	low	0	4	5	3	0	0
Glomerulonephritis, IGA	1	1992	1992	32.0	low	0	0	1	0	0	0
Glomerulonephritis, Lupus	1	2020	2020	4.0	low	0	0	0	0	1	0
Granulocytic Leukemia	4	1985	1989	37.0	low	0	4	0	0	0	0
Granulocytic Leukemia, Chronic	2	1991	2009	24.0	low	0	0	1	1	0	0
Grippe	3	2007	2019	10.3	low	0	0	0	1	2	0
Guillain-Barre Syndrome	3	2001	2019	11.3	low	0	0	0	1	2	0
Hansen Disease	1	1986	1986	38.0	low	0	1	0	0	0	0
Head and Neck Neoplasms	2	1989	2018	20.5	low	0	1	0	0	1	0
Hearing Loss	1	2011	2011	13.0	low	0	0	0	0	1	0
Heart Failure	1	2014	2014	10.0	low	0	0	0	0	1	0
Helicobacter Infections	1	1992	1992	32.0	low	0	0	1	0	0	0
Hematologic Malignancies	1	2019	2019	5.0	low	1	0	0	0	1	0
Hematologic Neoplasms	1	2019	2019	5.0	low	1	0	0	0	1	0
Hematoma	1	2010	2010	14.0	low	0	0	0	1	0	0
Hemolysis	2	1985	1996	33.5	low	0	1	1	0	0	0
Hepatocellular Carcinoma	5	1978	2015	22.2	low	0	1	1	0	3	0
HIV Coinfection	3	1996	2013	21.7	low	0	0	2	0	1	0
HIV Infections	3	1996	2013	21.7	low	0	0	2	0	1	0
Hymenolepiasis	1	1995	1995	29.0	low	0	0	1	0	0	0
Hyperactivity, Motor	1	2011	2011	13.0	low	0	0	0	0	1	0
Hypercholesterolemia	1	2018	2018	6.0	low	0	0	0	0	1	0
Hyperplasia	2	1978	1989	40.5	low	0	2	0	0	0	0
Hypertension	1	1988	1988	36.0	low	0	1	0	0	0	0
Hypertrophy	1	2003	2003	21.0	low	0	0	0	1	0	0
Hypokalemia	1	2001	2001	23.0	low	0	0	0	1	0	0
Idiopathic Parkinson Disease	5	2010	2023	6.4	low	0	0	0	1	2	2
Inclusion Body Myopathy, Sporadic	1	2010	2010	14.0	low	0	0	0	1	0	0
Infarction, Middle Cerebral Artery	1	2005	2005	19.0	low	0	0	0	1	0	0
Infections, Coronavirus	1	2020	2020	4.0	low	0	0	0	0	1	0
Infections, Helicobacter	1	1992	1992	32.0	low	0	0	1	0	0	0
Infections, Orthomyxoviridae	1	2019	2019	5.0	low	0	0	0	0	1	0
Infections, Pasteurella	1	2011	2011	13.0	low	0	0	0	0	1	0
Infections, Reoviridae	1	2012	2012	12.0	low	0	0	0	0	1	0
Inflammation	5	1996	2022	10.2	low	0	0	1	0	2	2
Inflammatory Bowel Diseases	1	2014	2014	10.0	low	0	0	0	0	1	0
Influenza, Human	3	2007	2019	10.3	low	0	0	0	1	2	0
Injuries, Spinal	1	2015	2015	9.0	low	1	0	0	0	1	0
Injury, Ischemia-Reperfusion	1	2015	2015	9.0	low	0	0	0	0	1	0
Innate Inflammatory Response	5	1996	2022	10.2	low	0	0	1	0	2	2
Insulin Resistance	20	2002	2023	13.3	low	1	0	0	10	8	2
Insulin Sensitivity	20	2002	2023	13.3	low	1	0	0	10	8	2
Interstitial Cell Tumor	1	1984	1984	40.0	low	0	1	0	0	0	0
Intestinal Diseases	1	1993	1993	31.0	low	0	0	1	0	0	0
Invasiveness, Neoplasm	9	1997	2013	19.8	low	0	0	1	7	1	0
Ischemia	1	1993	1993	31.0	low	0	0	1	0	0	0
Kahler Disease	2	1994	2006	24.0	low	0	0	1	1	0	0
Kidney Diseases	1	1992	1992	32.0	low	0	0	1	0	0	0
Kidney Neoplasms	4	1983	2004	27.5	low	0	1	2	1	0	0
Kidney, Polycystic	1	2010	2010	14.0	low	0	0	0	1	0	0
Leprosy	1	1986	1986	38.0	low	0	1	0	0	0	0
Leucocythaemia	2	2002	2012	17.0	low	0	0	0	1	1	0
Leukemia	2	2002	2012	17.0	low	0	0	0	1	1	0
Leukemia L 1210	1	2011	2011	13.0	low	0	0	0	0	1	0
Leukemia L5178	1	1989	1989	35.0	low	0	1	0	0	0	0
Leukemia, Basophilic, Acute	1	2000	2000	24.0	low	0	0	1	0	0	0
Leukemia, Lymphoblastic, Acute, T Cell	1	1991	1991	33.0	low	0	0	1	0	0	0
Leukemia, Lymphocytic	3	1986	2013	28.7	low	0	2	0	0	1	0
Leukemia, Lymphoid	3	1986	2013	28.7	low	0	2	0	0	1	0
Leukemia, Myelogenous, Chronic, BCR-ABL Positive	2	1991	2009	24.0	low	0	0	1	1	0	0
Leukemia, Myeloid	4	1985	1989	37.0	low	0	4	0	0	0	0
Leukemia, Myeloid, Acute	5	1985	1988	38.0	low	0	5	0	0	0	0
Leukemia, Pre-B-Cell	1	1991	1991	33.0	low	0	0	1	0	0	0
Leukemia, Promyelocytic, Acute	2	1989	1993	33.0	low	0	1	1	0	0	0
Leukemic Infiltration	1	1998	1998	26.0	low	0	0	1	0	0	0
Leukodystrophy, Metachromatic	1	1980	1980	44.0	low	0	1	0	0	0	0
Lipidoses	3	1977	1980	46.0	low	0	3	0	0	0	0
Liver Cirrhosis	1	1991	1991	33.0	low	0	0	1	0	0	0
Liver Neoplasms	6	1978	2013	32.3	low	0	2	3	0	1	0
Local Neoplasm Recurrence	3	2012	2022	6.3	low	0	0	0	0	2	1
Lung Adenocarcinoma	1	2011	2011	13.0	low	0	0	0	0	1	0
Lung Diseases, Interstitial	1	2010	2010	14.0	low	0	0	0	1	0	0
Lung Neoplasms	23	1979	2018	20.4	low	2	2	6	8	7	0
Lupus Nephritis	1	2020	2020	4.0	low	0	0	0	0	1	0
Lymph Node Metastasis	1	1991	1991	33.0	low	0	0	1	0	0	0
Lymphocytopenia	1	2011	2011	13.0	low	0	0	0	0	1	0
Lymphoma	3	1991	2019	17.0	low	1	0	1	0	2	0
Lymphoma, T-Cell	1	1995	1995	29.0	low	0	0	1	0	0	0
Lymphopenia	1	2011	2011	13.0	low	0	0	0	0	1	0
Lysosomal Enzyme Disorders	3	1992	2010	24.7	low	0	0	2	1	0	0
Lysosomal Enzyme Disorders, Nervous System	1	2007	2007	17.0	low	0	0	0	1	0	0
Malignant Melanoma	55	1984	2023	25.8	low	3	13	22	13	6	1
Medulloblastoma	1	1997	1997	27.0	low	0	0	1	0	0	0
Melanoma	55	1984	2023	25.8	low	3	13	22	13	6	1
Meningeal Neoplasms	2	1989	1990	34.5	low	0	1	1	0	0	0
Meningioma	3	1989	2021	24.0	low	0	1	1	0	0	1
Metabolic Diseases	3	2010	2022	7.3	low	0	0	0	1	1	1
Metabolic Syndrome	3	2011	2015	10.7	low	0	0	0	0	3	0
Metastase	13	1993	2019	19.2	low	0	0	7	2	4	0
Mole, Skin	2	1988	2002	29.0	low	0	1	0	1	0	0
Monosomy	1	1990	1990	34.0	low	0	0	1	0	0	0
Mouth Neoplasms	2	1986	2012	25.0	low	0	1	0	0	1	0
MS (Multiple Sclerosis)	1	1998	1998	26.0	low	0	0	1	0	0	0
Mucopolysaccharidoses	1	1980	1980	44.0	low	0	1	0	0	0	0
Mucopolysaccharidosis	1	1980	1980	44.0	low	0	1	0	0	0	0
Mucopolysaccharidosis I	1	1980	1980	44.0	low	0	1	0	0	0	0
Mucopolysaccharidosis II	1	2017	2017	7.0	low	0	0	0	0	1	0
Mucopolysaccharidosis III	9	1980	2021	15.0	low	0	1	0	2	5	1
Mucopolysaccharidosis IV	1	1980	1980	44.0	low	0	1	0	0	0	0
Mucopolysaccharidosis VI	1	1980	1980	44.0	low	0	1	0	0	0	0
Multiple Myeloma	2	1994	2006	24.0	low	0	0	1	1	0	0
Multiple Sclerosis	1	1998	1998	26.0	low	0	0	1	0	0	0
Multiple Sclerosis, Chronic Progressive	1	2003	2003	21.0	low	0	0	0	1	0	0
Multiple Sclerosis, Relapsing-Remitting	2	2001	2003	22.0	low	0	0	0	2	0	0
Muscle Contraction	1	2000	2000	24.0	low	0	0	1	0	0	0
Myositis, Inclusion Body	1	2010	2010	14.0	low	0	0	0	1	0	0
Narcolepsy	1	2015	2015	9.0	low	0	0	0	0	1	0
Necrosis	1	2013	2013	11.0	low	0	0	0	0	1	0
Neoplasm Metastasis	13	1993	2019	19.2	low	0	0	7	2	4	0
Neoplasms	25	1980	2020	15.8	low	0	1	5	6	13	0
Neoplasms, Bronchial	1	2007	2007	17.0	low	0	0	0	1	0	0
Neoplasms, Nervous System	1	2005	2005	19.0	low	0	0	0	1	0	0
Neoplasms, Otorhinolaryngologic	1	1989	1989	35.0	low	0	1	0	0	0	0
Nervous System Diseases	1	1998	1998	26.0	low	0	0	1	0	0	0
Nervous System Disorders	1	1998	1998	26.0	low	0	0	1	0	0	0
Neural Tube Defects	1	1991	1991	33.0	low	0	0	1	0	0	0
Neuroblastoma	19	1976	2005	32.8	low	0	8	8	3	0	0
Neurocutaneous Disorders	1	2014	2014	10.0	low	0	0	0	0	1	0
Neurodegenerative Diseases	1	2016	2016	8.0	low	0	0	0	0	1	0
Neuroectodermal Tumors	1	2011	2011	13.0	low	0	0	0	0	1	0
Neuroectodermal Tumors, Primitive, Peripheral	1	1994	1994	30.0	low	0	0	1	0	0	0
Neuronal Ceroid-Lipofuscinoses	2	2014	2018	8.0	low	0	0	0	0	2	0
Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia	4	2008	2017	11.5	low	0	0	0	1	3	0
Nevi, Melanocytic	2	1992	2012	22.0	low	0	0	1	0	1	0
Nevus, Pigmented	2	1992	2012	22.0	low	0	0	1	0	1	0
Niemann-Pick Disease	1	1984	1984	40.0	low	0	1	0	0	0	0
Niemann-Pick Disease, Type C	4	2008	2017	11.5	low	0	0	0	1	3	0
Niemann-Pick Diseases	1	1984	1984	40.0	low	0	1	0	0	0	0
Obesity	7	2009	2022	8.1	low	0	0	0	1	5	1
Optic Nerve Diseases	1	2019	2019	5.0	low	0	0	0	0	1	0
Orthomyxoviridae Infections	1	2019	2019	5.0	low	0	0	0	0	1	0
Osteoarthritis	3	1995	2017	16.0	low	0	0	1	0	2	0
Ovarian Neoplasms	5	1986	2022	19.0	low	0	1	1	1	1	1
Pain	1	2016	2016	8.0	low	0	0	0	0	1	0
Pancreatic Neoplasms	2	1983	1991	37.0	low	0	1	1	0	0	0
Parkinson Disease	5	2010	2023	6.4	low	0	0	0	1	2	2
Periapical Cyst	1	2001	2001	23.0	low	0	0	0	1	0	0
Periapical Diseases	1	2001	2001	23.0	low	0	0	0	1	0	0
Peripheral Nerve Diseases	1	2016	2016	8.0	low	0	0	0	0	1	0
Peripheral Nervous System Diseases	1	2016	2016	8.0	low	0	0	0	0	1	0
Peroxisomal Disorders	1	2001	2001	23.0	low	0	0	0	1	0	0
Plasma Cell Tumor	1	2011	2011	13.0	low	0	0	0	0	1	0
Plasmacytoma	1	2011	2011	13.0	low	0	0	0	0	1	0
Pneumonia, Viral	1	2020	2020	4.0	low	0	0	0	0	1	0
Polycystic Kidney Diseases	1	2010	2010	14.0	low	0	0	0	1	0	0
Potassium Deficiency	1	2001	2001	23.0	low	0	0	0	1	0	0
Poultry Diseases	1	2003	2003	21.0	low	0	0	0	1	0	0
Precancerous Conditions	1	1978	1978	46.0	low	0	1	0	0	0	0
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1	1991	1991	33.0	low	0	0	1	0	0	0
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1	1991	1991	33.0	low	0	0	1	0	0	0
Pregnancy	16	1979	2012	29.6	low	0	5	8	1	2	0
Proteinuria	2	2003	2020	12.5	low	0	0	0	1	1	0
Recrudescence	1	2007	2007	17.0	low	0	0	0	1	0	0
Rectal Neoplasms	1	1983	1983	41.0	low	0	1	0	0	0	0
Reflex, Abnormal	1	2000	2000	24.0	low	0	0	1	0	0	0
Reperfusion Injury	1	2015	2015	9.0	low	0	0	0	0	1	0
Retinoblastoma	2	1988	2015	22.5	low	0	1	0	0	1	0
Rheumatoid Arthritis	1	2012	2012	12.0	low	0	0	0	0	1	0
Rotavirus Infections	2	1998	2011	19.5	low	0	0	1	0	1	0
Salmonella Infections, Animal	1	2003	2003	21.0	low	0	0	0	1	0	0
Sarcoidosis	1	2010	2010	14.0	low	0	0	0	1	0	0
Sarcoma	1	2019	2019	5.0	low	0	0	0	0	1	0
Sarcoma, Epithelioid	1	2019	2019	5.0	low	0	0	0	0	1	0
Schizophrenia	1	1988	1988	36.0	low	0	1	0	0	0	0
Seizures	2	2001	2022	12.5	low	0	0	0	1	0	1
Sensitivity and Specificity	5	1990	2014	19.8	low	0	0	2	1	2	0
Skin Diseases	2	1989	2008	25.5	low	1	1	0	1	0	0
Skin Neoplasms	14	1988	2020	23.9	low	1	2	5	6	1	0
Small Fiber Neuropathy	1	2016	2016	8.0	low	0	0	0	0	1	0
Sphingolipid Storage Diseases	2	1992	1995	30.5	low	0	0	2	0	0	0
Stomach Neoplasms	4	1991	2001	30.0	low	0	0	3	1	0	0
Stomach Ulcer	1	2013	2013	11.0	low	0	0	0	0	1	0
Swine Diseases	1	1998	1998	26.0	low	0	0	1	0	0	0
Symptom Cluster	2	2003	2004	20.5	low	0	0	0	2	0	0
Syndrome	2	2003	2004	20.5	low	0	0	0	2	0	0
T-Cell Lymphoma	1	1995	1995	29.0	low	0	0	1	0	0	0
Tauopathies	1	2021	2021	3.0	low	0	0	0	0	0	1
Tay-Sachs Disease	1	1983	1983	41.0	low	0	1	0	0	0	0
Teratoma	2	1981	2000	33.5	low	0	1	1	0	0	0
Tetraploid	1	2010	2010	14.0	low	0	0	0	1	0	0
Thyroid Neoplasms	1	1990	1990	34.0	low	0	0	1	0	0	0
Tremor	1	2000	2000	24.0	low	0	0	1	0	0	0
Triple Negative Breast Neoplasms	1	2019	2019	5.0	low	0	0	0	0	1	0
Urinary Bladder Neoplasms	6	2001	2013	19.0	low	0	0	0	5	1	0
Uterine Neoplasms	1	1996	1996	28.0	low	0	0	1	0	0	0
Uveal Neoplasms	1	1996	1996	28.0	low	0	0	1	0	0	0
Vitamin D Deficiency	1	2011	2011	13.0	low	0	0	0	0	1	0
Vitiligo	1	2008	2008	16.0	low	1	0	0	1	0	0
Waldenstrom Macroglobulinemia	1	1978	1978	46.0	low	0	1	0	0	0	0
Wallerian Degeneration	1	2000	2000	24.0	low	0	0	1	0	0	0
Weight Loss	1	2009	2009	15.0	low	0	0	0	1	0	0
Weight Reduction	1	2009	2009	15.0	low	0	0	0	1	0	0
Zellweger Syndrome	1	2001	2001	23.0	low	0	0	0	1	0	0

Safety/Toxicity (6)

Article	Year
Antibody-dependent cell-mediated cytotoxicity induced by active immunotherapy based on racotumomab in non-small cell lung cancer patients. Cancer immunology, immunotherapy : CII, , Volume: 67, Issue:8	2018
Increased Expression of Simple Ganglioside Species GM2 and GM3 Detected by MALDI Imaging Mass Spectrometry in a Combined Rat Model of Aβ Toxicity and Stroke. PloS one, , Volume: 10, Issue:6	2015
Synthesis and cytotoxicity assay of four ganglioside GM3 analogues. European journal of medicinal chemistry, , Mar-21, Volume: 75	2014
Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody. Molecular immunology, , Volume: 48, Issue:8	2011
Toxicity of a GM3 cancer vaccine in Macaca fascicularis monkey: a 12-month study. Human & experimental toxicology, , Volume: 21, Issue:5	2002
Induction of nitric oxide production by ganglioside GM3 in murine peritoneal macrophages activated for tumor cytotoxicity. In vivo (Athens, Greece), , Volume: 12, Issue:3

Pharmacokinetics (2)

Article	Year
Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids. The Analyst, , Mar-07, Volume: 136, Issue:5	2011
Fluorescence-topographic NSOM directly visualizes peak-valley polarities of GM1/GM3 rafts in cell membrane fluctuations. Journal of lipid research, , Volume: 49, Issue:10	2008

Dosage (2)

Article	Year
Correction of murine mucopolysaccharidosis type IIIA central nervous system pathology by intracerebroventricular lentiviral-mediated gene delivery. The journal of gene medicine, , Volume: 16, Issue:11-12
No difference in glycosphingolipid metabolism and mitochondrial function in glucocorticoid-induced insulin resistance in healthy men. The Journal of clinical endocrinology and metabolism, , Volume: 98, Issue:3	2013

Interactions (1)

Article	Year
Clinical study of ganglioside (GM) combined with methylprednisolone (MP) for early acute spinal injury. Pakistan journal of pharmaceutical sciences, , Volume: 28, Issue:2 Suppl	2015