Page last updated: 2024-11-05

arsenamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Arsenamide: Proposed chemotherapeutic agent against filaria and trichomonas. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10749
SCHEMBL ID381665
MeSH IDM0001720

Synonyms (32)

Synonym
disodium salt of the s,s-diester of p-carbamoyldithiobenzenearsonous acid with mercaptoacetic acid
capariside
p-(bis(carboxymethylmercapto)arsino)benzamide
(((4-(aminocarbonyl)phenyl)arsinidine)bis(thio))biacetic acid
bis(carboxymethylmercapto)(p-carbamylphenyl)-arsine
thioarsenite
thiacetarsamidum
4-carbamylphenyl biscarboxymethylthioarsenite
arsenamide
acetic acid, 2,2'-(((4-(aminocarbonyl)phenyl)arsinidene)bis(thio))bis-
dithioglycolyl p-arsenobenzamide
benzamide, p-bis(carboxymethylmercapto)arsino-
thiacetarsamide
brn 3438926
acetic acid, mercapto-, p-carbamoyldithiobenzenearsonite (2:1)
4-carbamylphenyl bis(carboxymethylthio)arsenite
2-[(4-carbamoylphenyl)-(carboxymethylsulfanyl)arsanyl]sulfanylacetic acid
531-72-6
unii-vmf4ely9tz
thiacetarsamide [inn:dcf]
3-16-00-00978 (beilstein handbook reference)
vmf4ely9tz ,
thiacetarsamide [usp]
thiacetarsamide [mi]
2,2'-(((4-(aminocarbonyl)phenyl)arsinidene)bis(thio))bisacetic acid
(((p-carbamoylphenyl)arsylene)dithio)diacetic acid
benzamide, p-bis(carboxymethylmercapto)arsino
thiacetarsamide [mart.]
SCHEMBL381665
DTXSID10201182
Q4796424
AKOS040754184

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
"A microcomputer program using an electronic spreadsheet program was developed to calculate pharmacokinetic values of thiacetarsamide sodium, a drug used to kill the adult heartworm (Dirofilaria immitis) parasite of the dog."( Electronic spreadsheet program for estimating two-compartment intravenous pharmacokinetic parameters by least squares linear regression analysis.
Holmes, RA; McCall, JW; Wilson, RC, 1986
)
0.27

Compound-Compound Interactions

ExcerptReferenceRelevance
"The simultaneous detection of arsenic and sulfur in thioarsenicals was achieved using xenon-based collision-cell inductively coupled plasma (ICP) mass spectrometry (MS) in combination with high-performance liquid chromatography."( Complementary molecular and elemental detection of speciated thioarsenicals using ESI-MS in combination with a xenon-based collision-cell ICP-MS with application to fortified NIST freeze-dried urine.
Caruso, JA; Conklin, SD; Creed, JT; Creed, PA; Ellis, JL; Gallawa, CM; Kubachka, KM; Young, AR, 2008
)
0.35

Dosage Studied

ExcerptRelevanceReference
" Vessels were exposed to thiacetarsamide and dose-response relationships were applied to methacholine and nitroglycerin."( Thiacetarsamide depresses relaxation of canine pulmonary artery in vitro.
Kaiser, L; Maksimowich, DS; Williams, JF, 1996
)
0.29
" Cumulative dose-response relations to norepinephrine, nitroglycerin, and methacholine were determined."( Effect of arsenical drugs on in vitro vascular responses of pulmonary artery from heartworm-infected dogs.
Bell, TG; Kaiser, L; Maksimowich, DS; Williams, JF, 1997
)
0.3
" The CFS-like lethargy, with accompanying symptoms and signs, of the four animals obtained a complete remission after intravenous treatment with this drug at low dosage (0."( Chronic fatigue syndrome in horses: diagnosis and treatment of 4 cases.
Tarello, W, 2001
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (72)

TimeframeStudies, This Drug (%)All Drugs %
pre-199042 (58.33)18.7374
1990's12 (16.67)18.2507
2000's12 (16.67)29.6817
2010's3 (4.17)24.3611
2020's3 (4.17)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 9.91

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index9.91 (24.57)
Research Supply Index4.36 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (9.91)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews5 (6.49%)6.00%
Case Studies7 (9.09%)4.05%
Observational0 (0.00%)0.25%
Other65 (84.42%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]