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mebeverine and Sensitivity and Specificity

mebeverine has been researched along with Sensitivity and Specificity in 7 studies

mebeverine: RN given refers to parent cpd; structure

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" The developed spectrophotometric methods depend on determination of MEH and DF in the combined dosage form using the successive derivative ratio spectra method which depends on derivatization of the obtained ratio spectra in two steps using methanol as a solvent and measuring MEH at 226."1.39Validated chromatographic and spectrophotometric methods for analysis of some amoebicide drugs in their combined pharmaceutical preparation. ( Abdelaleem, EA; Abdelwahab, NS, 2013)
"Mebeverine was used as the internal standard for both analytes."1.35Validated LC-MS/MS method for determination of Alverine and one of its hydroxy metabolites in human plasma along with its application to a bioequivalence study. ( Gomes, NA; Joshi, SS; Laud, A; Pudage, A; Tandel, JA; Vaidya, VV, 2009)
" The proposed method was applied for analysis of mebeverine in commercially available tablets dosage formulations."1.33A validated chiral HPLC method for the determination of mebeverine HCl enantiomers in pharmaceutical dosage forms and spiked rat plasma. ( Abdine, HH; Aboul-Enein, HY; Radwan, MA, 2006)
"Mebeverine alcohol was used as a model compound, and dog plasma was employed as the biological matrix for these studies."1.28Combined supercritical fluid extraction/solid-phase extraction with octadecylsilane cartridges as a sample preparation technique for the ultratrace analysis of a drug metabolite in plasma. ( Cooper, LM; Liu, H; Pinkston, JD; Raynie, DE; Wehmeyer, KR, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mabrouk, M1
El-Fatatry, H1
Hewala, I1
Emam, E1
Moskaleva, NE1
Baranov, PA1
Mesonzhnik, NV1
Appolonova, SA1
Gomes, NA1
Laud, A1
Pudage, A1
Joshi, SS1
Vaidya, VV1
Tandel, JA1
Abdelaleem, EA1
Abdelwahab, NS1
Radwan, MA1
Abdine, HH1
Aboul-Enein, HY1
Tulich, LJ1
Randall, JL1
Kelm, GR1
Wehmeyer, KR2
Liu, H1
Cooper, LM1
Raynie, DE1
Pinkston, JD1

Other Studies

7 other studies available for mebeverine and Sensitivity and Specificity

ArticleYear
Development and application of a novel, dual-mode gradient, stability-indicating HPLC-DAD method for the simultaneous determination and purity assessment of mebeverine hydrochloride, diloxanide furoate and their corresponding major degradation products in
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 83

    Topics: Administration, Oral; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Furans; G

2013
HPLC-MS/MS method for the simultaneous quantification of desmethylmebeverine acid, mebeverine acid and mebeverine alcohol in human plasma along with its application to a pharmacokinetics study.
    Journal of pharmaceutical and biomedical analysis, 2017, May-10, Volume: 138

    Topics: Chromatography, High Pressure Liquid; Humans; Phenethylamines; Plasma; Reproducibility of Results; S

2017
Validated LC-MS/MS method for determination of Alverine and one of its hydroxy metabolites in human plasma along with its application to a bioequivalence study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jan-15, Volume: 877, Issue:3

    Topics: Chromatography, Liquid; Humans; Least-Squares Analysis; Phenethylamines; Propylamines; Reference Sta

2009
Validated chromatographic and spectrophotometric methods for analysis of some amoebicide drugs in their combined pharmaceutical preparation.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:1

    Topics: Amebicides; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug C

2013
A validated chiral HPLC method for the determination of mebeverine HCl enantiomers in pharmaceutical dosage forms and spiked rat plasma.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Phenethylamines; Rats; Reproducibilit

2006
Determination of two mebeverine metabolites, mebeverine alcohol and desmethylmebeverine alcohol, in human plasma by a dual stable isotope-based gas chromatographic-mass spectrometric method.
    Journal of chromatography. B, Biomedical applications, 1996, Jul-12, Volume: 682, Issue:2

    Topics: Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; I

1996
Combined supercritical fluid extraction/solid-phase extraction with octadecylsilane cartridges as a sample preparation technique for the ultratrace analysis of a drug metabolite in plasma.
    Analytical chemistry, 1992, Apr-01, Volume: 64, Issue:7

    Topics: Animals; Chromatography, Gas; Dogs; Mass Spectrometry; Phenethylamines; Sensitivity and Specificity

1992